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Prof. MD PhD J. Kluin

Positions
Medical Specialist, Full Professor
Main activities
Patient care
Specialisation
Congenital cardiac surgery in pediatric and adult patients. Heart valve reconstruction surgery.
Focus of research

- regenerative medicine

- heart valve tissue engineering

- imaging (4D flow MRI) of cardiac defects

- surgery for aortic valve regurgitation and aortic aneurysms

- congenital heart surgery

- surgery for asymptomatic patients with severe mitral regurgitation

- aortic valve homeostasis

Key publications
  • Kluin Jolanda, Talacua Hanna, Smits Anthal I. P. M., Emmert Maximilian Y., Brugmans Marieke C. P., Fioretta Emanuela S., Dijkman Petra E., Söntjens Serge H. M., Duijvelshoff Renée, Dekker Sylvia, Janssen-van den Broek Marloes W. J. T., Lintas Valentina, Vink Aryan, Hoerstrup Simon P., Janssen Henk M., Dankers Patricia Y. W., Baaijens Frank P. T., Bouten Carlijn V. C. In situ heart valve tissue engineering using a bioresorbable elastomeric implant - From material design to 12 months follow-up in sheep Biomaterials 2017;125:101-117 [PubMed]
  • de Heer Linda M., Budde Ricardo P. J., Mali Willem P. Th M., de Vos Alexander M., van Herwerden Lex A., Kluin Jolanda Aortic root dimension changes during systole and diastole: evaluation with ECG-gated multidetector row computed tomography international journal of cardiovascular imaging 2011;27 (8):1195-1204 [PubMed]
  • Hjortnaes Jesper, Shapero Kayle, Goettsch Claudia, Hutcheson Joshua D., Keegan Joshua, Kluin Jolanda, Mayer John E., Bischoff Joyce, Aikawa Elena Valvular interstitial cells suppress calcification of valvular endothelial cells Atherosclerosis 2015;242 (1):251-260 [PubMed]
  • Houthuizen Patrick, van Garsse Leen A. F. M., Poels Thomas T., de Jaegere Peter, van der Boon Robert M. A., Swinkels Ben M., ten Berg Jurriën M., van der Kley Frank, Schalij Martin J., Baan Jan, Cocchieri Ricardo, Brueren Guus R. G., van Straten Albert H. M., den Heijer Peter, Bentala Mohamed, van Ommen Vincent, Kluin Jolanda, Stella Pieter R., Prins Martin H., Maessen Jos G., Prinzen Frits W. Left Bundle-Branch Block Induced by Transcatheter Aortic Valve Implantation Increases Risk of Death Circulation 2012;126 (6):720-728 [PubMed]
  • Onsea Kevin, Agostoni Pierfrancesco, Samim Mariam, Voskuil Michiel, Kluin Jolanda, Budde Ricardo, Hendrikse Jeroen, Ramjankhan Faiz, van Klarenbosch Jan, Doesburg Pieter, Sieswerda Gertjan, Stella Pieter First-in-man experience with a new embolic deflection device in transcatheter aortic valve interventions EuroIntervention 2012;8 (1):51-56 [PubMed]
All Publications
Research programmes

Prof. MD PhD J. Kluin (Translational research in cardio-thoracic surgery and the application of regenerative medicine technologies)

- heart valve tissue engineering

- aortic valve homeostasis and pathology

- hybrid heart development

- imaging

PhD Students
MD R. Janssen

Current research funding
  • AMC
  • AMC (Vrijgesteld)
  • BRITISH HEART FOUNDATION
  • Daiichi-Sankyo Nederland B.V.
  • Europese Unie
  • Heart Valve Society
  • Nederlandse Hartstichting
  • Stichting AMC Foundation