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V.E.A. Gerdes MD PhD

Position
Medical Specialist
Main activities
Education, Patient care, Research
Specialisation
Internal medicine, vascular medicine
Focus of research

Obesity and treatment of obesity

Diabetes

Vascular medicine

 

Key publications
  • Boerlage Thomas C. C., Westerink Floris, van de Laar Arnold W. J. M., Hutten Barbara A., Brandjes Desiderius P. M., Gerdes Victor E. A. Gastrointestinal symptoms before and after laparoscopic Roux-en-Y gastric bypass: a longitudinal assessment Surgery for obesity and related diseases 2019;15 (6):871-877 [PubMed]
  • Gerards Maaike C., Venema Gerdien E., Patberg Kornelis W., Kross Martijn, Potter van Loon Bert Jan, Hageman Ilse M. G., Snijders Dominic, Brandjes Dees P. M., Hoekstra Joost B. L., Vriesendorp Titia M., Gerdes Victor E. A. Dapagliflozin for prednisone-induced hyperglycemia in acute exacerbation of chronic obstructive pulmonary disease Diabetes, obesity & metabolism 2018;20 (5):1306-1310 [PubMed]
  • Celik Funda, Huitema Alwin D. R., Hooijberg Jan H., van de Laar Arnold W. J. M., Brandjes Dees P. M., Gerdes Victor E. A. Fixed-dose enoxaparin after bariatric surgery: the influence of body weight on peak anti-xa levels Obesity surgery 2015;25 (4):628-634 [PubMed]
  • Aarts Floor, Radhakishun Nalini N. E., van Vliet Mariska, Geenen Rinie, Von Rosenstiel Ines A., Hinnen Chris, Beijnen Jos H., Brandjes Dees P. M., Diamant Michaela, Gerdes Victor E. A. Gastric bypass may promote weight loss in overweight partners Journal of the American Board of Family Medicine 2015;28 (1):90-96 [PubMed]
  • Boerlage Thomas C C, Westerink Floris, Poland Dennis C W, Huibregtse Inge L, Acherman Yair I Z, Gerdes Victor E A Fecal Calprotectin, Elastase, and Alpha-1-Antitrypsin Levels After Roux-en-Y Gastric Bypass; Calprotectin Is Significantly Elevated in the Majority of Patients Obesity surgery 2016;26 (12):2974-2980 [PubMed]
All Publications
Curriculum Vitae

Victor Gerdes is internist at the department of vascular medicine and the laboratory for experimental vascular medicine of the Amsterdam UMC, location AMC, and the department of obesity surgery of the Spaarne Gasthuis. Between 2003 and 2018 he was internist at the Slotervaart Hospital / MC Slotervaart were he performed, besides his cinical work and teaching, several research projects. For this he built and funded together with his collaegues his own group of PhD candidates. The focus of his research is vascular medicine and diabetes, with in the last years more and more emphasis on the treatment of severe obesity. 

Studies on the effects of hormones and endocrine disorders on thrombosis and haemostasis were performed in collaboration prof DMP Brandjes (Slotervaart / AMC) as well as with the AMC (prof HR Buller, prof JCM Meijers, prof E Fliers), LUMC (prof FR Rosendaal, prof SC Cannegieter) and Varese (dr A Squizzato). For studies on diabetes (complications, ethnicity, effect of corticosteroids) he collaborated with the AMC (prof JBL Hoekstra, dr F Holleman) and Isala Zwolle (dr T Vriesendorp). Studies on the influence of infections on thrombosis and haemostasis were performed together with prof ECM van Gorp and prof DPM Brandjes and the AMC (prof HR Buller and prof JCM Meijers). Together with prof B Loos of ACTA he has performed several studies on the relationship between diabetes, periodontitis and other oral complications. From 2007 together with the surgeons he built a rapidly growing team for obesity surgery. Along with the clinical work studies on the effects of obesity surgery on thrombosis and bleeding, on psychological aspects, on gastrointestinal symptoms and symptomatic gallstone disease and on metabolic effects were designed and performed.

Two large projects were started at the Slotervaart and are at present continued at the Spaarne Gasthuis, were the obesity surgery team continues after closure of the MC Slotervaart, together with the AMC. The first is the Baria study: in this project 500 severe obese patients are followed before and at least 2 years after surgery. Collection of fecal microbiome, clinical data, metabolic characteristics, metabolites, psychological datais performed before and the years after surgery along with biopsies of liver, fat tissue, intestinal tissue and portal vein blood sample, in order to investigate how microbiome  and metabolites influence NAFLD and diabetes. Many additional studies will be performed using these unique data. This project is a collaboration of the AMC (prof M Nieuwdorp, prof AK Groen), Spaarne Gasthuis, University of Goteborg, University of Copenhagen and UMCG, supported by grants from NNF, SKWOSZ, Spaarne Gasthuis and UMCG. The second project is the Upgrade study, double blind placebo controled RCT on the effect of 6 months of ursodeocycholic acid on symptomatic gallstone disease after bariatric surgery. A total of 972 have been included at the MC Slotervaart, OLVG and MC Lelystad and are in follow-up until the beginning of 2021. The study is a collaboration between the Spaarne Gasthuis and the AMC and supported by grants form ZonMW, SKWOSZ and Zambon. 

Current research funding
  • Vascular Research Network BV