Dr. A. Lok publications


Publications Dr. A. Lok

PhD student
Main activities
Patient care, Research
Biological psychiatry
Focus of research

Biological psychiatry. MDD, PTSD.


  • Bergfeld IO, Mantione M, Figee M, Schuurman PR, Lok A , Denys D, Treatment-resistant depression and suicidality. J AFFECT DISORDERS 2018;235:362-367 [PubMed]
  • Lok A , Frijling JL, van Zuiden M, Posttraumatische stressstoornis. NED TIJDSCHR GENEESKD 2018;161:D1905 [PubMed]
  • ter Horst DM, Schene AH, Figueroa CA, Assies J , Lok A , Bockting CLH, Ruhé HG, Mocking RJT, Cortisol, dehydroepiandrosterone sulfate, fatty acids, and their relation in recurrent depression. PSYCHONEUROENDOCRINO 2018;100:203-212 [PubMed]


  • van Zuiden M, Haverkort SQ, Tan Z, Daams J, Lok A , Olff M, DHEA and DHEA-S levels in posttraumatic stress disorder: A meta-analytic review. PSYCHONEUROENDOCRINO 2017;84:76-82 [PubMed]
  • Vermeulen E, Stronks K, Snijder MB, Schene AH, Lok A , de Vries JH, Visser M, Brouwer IA, Nicolaou M, A combined high-sugar and high-saturated-fat dietary pattern is associated with more depressive symptoms in a multi-ethnic population: the HELIUS (Healthy Life in an Urban Setting) study. PUBLIC HEALTH NUTR 2017;20 (13):2374-2382 [PubMed]


  • de Vries GJ, Mocking R, Lok A , Assies J, Schene A, Olff M, Fatty acid concentrations in patients with posttraumatic stress disorder compared to healthy controls. J AFFECT DISORDERS 2016;205:351-359 [PubMed]


  • Assies J, Mocking RJT, Lok A , Koeter MWJ, Bockting CLH, Visser I , Pouwer F, Ruhé HG , Schene AH, Erythrocyte fatty acid profiles and plasma homocysteine, folate and vitamin B6 and B12 in recurrent depression: Implications for co-morbidity with cardiovascular disease. PSYCHIAT RES 2015;229 (3):992-998 [PubMed]
  • de Vries GJ, Lok A , Mocking R, Assies J, Schene A, Olff M, Altered one-carbon metabolism in posttraumatic stress disorder. J AFFECT DISORDERS 2015;184:277-285 [PubMed]
  • Mocking RJT , Pellikaan CM, Lok A , Assies J , Ruhé HG, Koeter MW, Visser I, Bockting CL, Olff M, Schene AH, DHEAS and cortisol/DHEAS-ratio in recurrent depression: State, or trait predicting 10-year recurrence?. PSYCHONEUROENDOCRINO 2015;59:91-101 [PubMed]


  • Assies J , Mocking RJT , Lok A , Ruhé HG, Pouwer F, Schene AH, Effects of oxidative stress on fatty acid- and one-carbon-metabolism in psychiatric and cardiovascular disease comorbidity. ACTA PSYCHIAT SCAND 2014;130 (3):163-180 [PubMed]
  • Lok A , Mocking RJT , Assies J , Koeter MW, Bockting CL, de Vries GJ, Visser I, Derks EM, Kayser M, Schene AH, The one-carbon-cycle and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism in recurrent major depressive disorder; influence of antidepressant use and depressive state?. J AFFECT DISORDERS 2014;166:115-123 [PubMed]


  • Bockting CLH, Mocking RJ, Lok A , Koeter MWJ, Schene AH, Therapygenetics: the 5HTTLPR as a biomarker for response to psychological therapy?. MOL PSYCHIATR 2013;18 (7):744-745 [PubMed]
  • Lok A. Time after Time; biological factors in the course of recurrent depression. s.l.: s.n.; 2013. 271p. ISBN 9789088917455 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Schene AH, Bockting CLH; copromotor(s): Koeter MWJ, Assies J)
  • Lok A , Bockting CLH, Koeter MWJ, Snieder H, Assies J , Mocking RJT , Vinkers CH, Kahn RS, Boks MP, Schene AH, Interaction between the MTHFR C677T polymorphism and traumatic childhood events predicts depression. TRANSL PSYCHIAT 2013;3:e288 [PubMed]
  • Mocking RJT, Lok A , Assies J, Koeter MWJ, Visser I , Ruhé HG , Bockting CLH, Schene AH, Ala54Thr fatty acid-binding protein 2 (FABP2) polymorphism in recurrent depression: associations with fatty acid concentrations and waist circumference. PLOS ONE 2013;8 (12):e82980 [PubMed]
  • Mocking RJT, Ruhé HG , Assies J, Lok A , Koeter MWJ, Visser I , Bockting CLH, Schene AH, Relationship between the hypothalamic-pituitary-adrenal-axis and fatty acid metabolism in recurrent depression. PSYCHONEUROENDOCRINO 2013;38 (9):1607-1617 [PubMed]


  • Bockting CLH, Lok A , Visser I , Assies J, Koeter MW, Schene AH, Lower cortisol levels predict recurrence in remitted patients with recurrent depression: A 5.5 year prospective study. PSYCHIAT RES 2012;200 (2-3):281-287 [PubMed]
  • Lok A , Assies J, Koeter MWJ, Bockting CLH, Wouters LF, Mocking RJT, Schene AH, Sustained medically unexplained physical symptoms in euthymic patients with recurrent depression: Predictive value for recurrence and associations with omega 3- and 6 fatty acids and 5-HTTLPR?. J AFFECT DISORDERS 2012;136 (3):604-611 [PubMed]
  • Lok A , Mocking RJT, Ruhé HG , Visser I , Koeter MWJ, Assies J, Bockting CLH, Olff M, Schene AH, Longitudinal hypothalamic-pituitary-adrenal axis trait and state effects in recurrent depression. PSYCHONEUROENDOCRINO 2012;37 (7):892-902 [PubMed]
  • Mocking RJT, Assies J, Koeter MWJ, Ruhé HG , Lok A , Schene AH, Bimodal Distribution of Fatty Acids in Recurrent Major Depressive Disorder. BIOL PSYCHIAT 2012;71 (1):E3-E5 [PubMed]
  • Mocking RJT, Assies J, Lok A , Ruhé HG , Koeter MWJ, Visser I , Bockting CLH, Schene AH, Statistical Methodological Issues in Handling of Fatty Acid Data: Percentage or Concentration, Imputation and Indices. LIPIDS 2012;47 (5):541-547 [PubMed]


  • de Boer J, Lok A , van 't Verlaat E, Duivenvoorden HJ, Bakker AB, Smit BJ, Work-related critical incidents in hospital-based health care providers and the risk of post-traumatic stress symptoms, anxiety, and depression: a meta-analysis. SOC SCI MED 2011;73 (2):316-326 [PubMed]


  • Assies J, Pouwer F, Lok A , Mocking RJT, Bockting CLH, Visser I , Abeling NGGM, Duran M, Schene AH, Plasma and Erythrocyte Fatty Acid Patterns in Patients with Recurrent Depression: A Matched Case-Control Study. PLOS ONE 2010;5 (5):e10635 [PubMed]
  • Lok A , Visscher TLS, Koeter MWJ, Assies J , Bockting CLH, Verschuren WMM, Gill A, Schene AH, The 'Weight' of Recurrent Depression: A Comparison between Individuals with Recurrent Depression and the General Population and the Influence of Antidepressants. PSYCHOTHER PSYCHOSOM 2010;79 (6):386-388 [PubMed]


  • Bermond B, Surachno S, Lok A , ten Berge IJM, Plasmans B, Kox C, Schuller E, Schellekens PTA, Hamel R, Memory functions in prednisone-treated kidney transplant patients. CLIN TRANSPLANT 2005;19 (4):512-517 [PubMed]


  • Assies J , Lok A , Bockting CL, Weverling GJ, Lieverse R, Visser I, Abeling NGGM, Duran M, Schene AH, Fatty acids and homocysteine levels in patients with recurrent depression: an explorative pilot study. PROSTAG LEUKOTR ESS 2004;70 (4):349-356 [PubMed]