Dr. J. Aten publications

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Publications Dr. J. Aten

Position
Scientific staff member (UD)
Main activities
Research, Teaching
Specialisation
pathology, immunology
Focus of research
  • Pathobiology of the glomerular visceral epithelial cell in development of nephrotic syndrome.
  • Pathogenesis of renal fibrosis.

2018

  • Rampanelli E, Ochodnicky P, Vissers JP, Butter LM, Claessen N, Calcagni A, Kors L, Gethings LA, Bakker SJ, de Borst MH, Navis GJ, Liebisch G, Speijer D, van den Bergh Weerman MA, Jung B, Aten J, Steenbergen E, Schmitz G, Ballabio A, Florquin S, Aerts JM, Leemans JC, Excessive dietary lipid intake provokes an acquired form of lysosomal lipid storage disease in the kidney. J PATHOL 2018;246 (4):470-484 [PubMed]

2017

  • Kinashi H, Falke LL, Nguyen TQ, Bovenschen N, Aten J, Leask A, Ito Y, Goldschmeding R, Connective tissue growth factor regulates fibrosis-associated renal lymphangiogenesis. KIDNEY INT 2017;92 (4):850-863 [PubMed]

2016

  • Marques ARA, Gabriel TL, Aten J, van Roomen CPAA, Ottenhoff R, Claessen N, Alfonso P, Irún P, Giraldo P, Aerts JMFG, van Eijk M, Gpnmb Is a Potential Marker for the Visceral Pathology in Niemann-Pick Type C Disease. PLOS ONE 2016;11 (1):e0147208 [PubMed]
  • Tol MJ, Ottenhoff R, van Eijk M, Zelcer N, Aten J, Houten SM, Geerts D, van Roomen C, Bierlaagh MC, Scheij S, Hoeksema MA, Aerts JM, Bogan JS, Dorn GW 2nd, Argmann CA, Verhoeven AJ, A PPARγ-Bnip3 Axis Couples Adipose Mitochondrial Fusion-Fission Balance to Systemic Insulin Sensitivity. DIABETES 2016;65 (9):2591-2605 [PubMed]
  • Vlahu CA, Aten J, de Graaff M, van Veen H, Everts V, de Waart DR, Struijk DG, Krediet RT, New Insights into the Effects of Chronic Kidney Failure and Dialysate Exposure on the Peritoneum. PERITON DIALYSIS INT 2016;36 (6):614-622 [PubMed]

2015

  • Arai H, Hayashi H, Takahashi K, Koide S, Sato W, Hasegawa M, Yamaguchi Y, Aten J, Ito Y, Yuzawa Y, Tubulointerstitial fibrosis in patients with IgG4-related kidney disease: pathological findings on repeat renal biopsy. RHEUMATOL INT 2015;35 (6):1093-1101 [PubMed]
  • Gerritsen KGF, Leeuwis JW, Koeners MP, Bakker SJL, van Oeveren W, Aten J, Tarnow L, Rossing P, Wetzels JFM, Joles JA, Kok RJ, Goldschmeding R, Nguyen TQ, Elevated Urinary Connective Tissue Growth Factor in Diabetic Nephropathy Is Caused by Local Production and Tubular Dysfunction. J DIABETES RES 2015;2015:539787 [PubMed]
  • Herrera Moro Chao D, Kallemeijn WW, Marques ARA, Orre M, Ottenhoff R, van Roomen C, Foppen E, Renner MC, Moeton M, van Eijk M, Boot RG, Kamphuis W, Hol EM, Aten J, Overkleeft HS, Kalsbeek A, Aerts JMFG, Visualization of Active Glucocerebrosidase in Rodent Brain with High Spatial Resolution following In Situ Labeling with Fluorescent Activity Based Probes. PLOS ONE 2015;10 (9):e0138107 [PubMed]
  • Jebbink JM, Boot RG, Keijser R, Moerland PD, Aten J, Veenboer GJM, van Wely M, Buimer M, Ver Loren van Themaat E, Aerts JMFG, van der Post JAM, Afink GB, Ris-Stalpers C, Increased glucocerebrosidase expression and activity in preeclamptic placenta. PLACENTA 2015;36 (2):160-169 [PubMed]
  • Marques ARA, Aten J, Ottenhoff R, van Roomen CPAA, Herrera Moro D, Claessen N, Vinueza Veloz MF, Zhou K, Lin Z, Mirzaian M, Boot RG, de Zeeuw CI, Overkleeft HS, Yildiz Y, Aerts JMFG, Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice. PLOS ONE 2015;10 (8):e0135889 [PubMed]
  • Vlahu CA, de Graaff M, Aten J, Struijk DG, Krediet RT, Lymphangiogenesis and Lymphatic Absorption Are Related and Increased in Chronic Kidney Failure, Independent of Exposure to Dialysis Solutions. ADV PERIT DIAL 2015;31:21-25 [PubMed]

2014

  • Bakker PJ, Butter LM, Kors L, Teske GJD, Aten J, Sutterwala FS, Florquin S, Leemans JC, Nlrp3 is a key modulator of diet-induced nephropathy and renal cholesterol accumulation. KIDNEY INT 2014;85 (5):1112-1122 [PubMed]
  • Gabriel TL, Tol MJ, Ottenhof R, van Roomen C, Aten J, Claessen N, Hooibrink B, de Weijer B, Serlie MJ, Argmann C, van Elsenburg L, Aerts JMFG, van Eijk M, Lysosomal stress in obese adipose tissue macrophages contributes to MITF-dependent Gpnmb induction. DIABETES 2014;63 (10):3310-3323 [PubMed]
  • Gaspar P, Kallemeijn WW, Strijland A, Scheij S, van Eijk M, Aten J, Overkleeft HS, Balreira A, Zunke F, Schwake M, Sá Miranda C, Aerts JMFG, Action myoclonus-renal failure syndrome: diagnostic applications of activity-based probes and lipid analysis. J LIPID RES 2014;55 (1):138-145 [PubMed]
  • van Weeghel M, Ofman R, Argmann CA, Ruiter JPN, Claessen N, Oussoren SV, Wanders RJA, Aten J, Houten SM, Identification and characterization of Eci3, a murine kidney-specific Δ3,Δ2-enoyl-CoA isomerase. FASEB J 2014;28 (3):1365-1374 [PubMed]

2013

  • Sokolović A, van Roomen CPAA, Ottenhoff R, Scheij S, Hiralall JK, Claessen N, Aten J, Oude Elferink RPJ, Groen AK, Sokolović M, Fasting reduces liver fibrosis in a mouse model for chronic cholangiopathies. BBA-MOL BASIS DIS 2013;1832 (10):1482-1491 [PubMed]

2012

  • Kallemeijn WW, Li KY, Witte MD, Marques ARA, Aten J, Scheij S, Jiang J, Willems LI, Voorn-Brouwer TM, van Roomen CPAA, Ottenhoff R, Boot RG, van den Elst H, Walvoort MTC, Florea BI, Codée JDC, van der Marel GA, Aerts JMFG, Overkleeft HS, Novel Activity-Based Probes for Broad-Spectrum Profiling of Retaining beta-Exoglucosidases In Situ and In Vivo. ANGEW CHEM INT EDIT 2012;51 (50):12529-12533 [PubMed]
  • Lombardo E, van Roomen CPAA, van Puijvelde GH, Ottenhoff R, van Eijk M, Aten J, Kuiper J, Overkleeft HS, Groen AK, Verhoeven AJ, Aerts JMFG, Bietrix F, Correction of Liver Steatosis by a Hydrophobic Iminosugar Modulating Glycosphingolipids Metabolism. PLOS ONE 2012;7 (10):e38520-(10 p.) [PubMed]
  • Rops ALWMM, van den Hoven MJ, Veldman BA, Salemink S, Vervoort G, Elving LD, Aten J, Wetzels JF, van der Vlag J, Berden JHM, Urinary heparanase activity in patients with Type 1 and Type 2 diabetes. NEPHROL DIAL TRANSPL 2012;27 (7):2853-2861 [PubMed]
  • Sachs N, Claessen N, Aten J, Kreft M, Teske GJD, Koeman A, Zuurbier CJ, Janssen H, Sonnenberg A, Blood pressure influences end-stage renal disease of Cd151 knockout mice. J CLIN INVEST 2012;122 (1):348-358 [PubMed]
  • van Maldegem F, Wormhoudt TAM, Mulder MMS, Oud MECM, Schilder-Tol E, Musler AR, Aten J, Saeed P, Kersten MJ , Pals ST, van Noesel CJM, Bende RJ, Chlamydia psittaci-negative ocular adnexal marginal zone B-cell lymphomas have biased V(H)4-34 immunoglobulin gene expression and proliferate in a distinct inflammatory environment. LEUKEMIA 2012;26 (7):1647-1653 [PubMed]

2011

  • Aerts JM, Boot RG, van Eijk M, Groener J, Bijl N, Lombardo E, Bietrix FM, Dekker N, Groen AK, Ottenhoff R, van Roomen C, Aten J, Serlie M, Langeveld M, Wennekes T, Overkleeft HS, Glycosphingolipids and insulin resistance. ADV EXP MED BIOL 2011;721:99-119 [PubMed]
  • Bakermans AJ, Geraedts TR, van Weeghel M, Denis S, João Ferraz M, Aerts JMFG, Aten J, Nicolay K, Houten SM, Prompers JJ, Fasting-induced myocardial lipid accumulation in long-chain acyl-CoA dehydrogenase knockout mice is accompanied by impaired left ventricular function. CIRC-CARDIOVASC IMAG 2011;4 (5):558-565 [PubMed]
  • Ito Y. Connective tissue growth factor in renal development and injury. s.l.: s.n.; 2011. 227p. ISBN 9789090262949 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Matsuo S, Weening JJ; copromotor(s): Goldschmeding R, Aten J)
  • Ito Y, Aten J, Nguyen TQ, Joles JA, Matsuo S, Weening JJ, Goldschmeding R, Involvement of Connective Tissue Growth Factor in Human and Experimental Hypertensive Nephrosclerosis. NEPHRON EXP NEPHROL 2011;117 (1):e9-e20 [PubMed]
  • Reuwer A, van Eijk M, Houttuijn-Bloemendaal F, van der Loos C, Claessen N, Teeling P, Kastelein JJ, Hamann J, Goffin V, von der Thüsen J, Twickler M, Aten J, The prolactin receptor is expressed in macrophages within human carotid atherosclerotic plaques: a role for prolactin in atherogenesis?. J ENDOCRINOL 2011;208 (2):107-117 [PubMed]

2010

  • Aerts JM, Boot RG, van Eijk M, Groener J, Bijl N, Lombardo E, Bietrix FM, Dekker N, Groen AK, Ottenhoff R, van Roomen C, Aten J, Serlie M, Langeveld M, Wennekes T, Overkleeft HS. Glycosphingolipids and insulin resistance in: Cowart A, editor. Sphingolipids and Metabolic Disease. S.l.: Landes Bioscience and Springer Science; 2010., p. 20-41
  • de Boer OJ, van der Meer JJ, Teeling P, van der Loos CM, Idu MM, van Maldegem F, Aten J, van der Wal AC, Differential expression of interleukin-17 family cytokines in intact and complicated human atherosclerotic plaques. J PATHOL 2010;220 (4):499-508 [PubMed]
  • Ito Y, Goldschmeding R, Kasuga H, Claessen N, Nakayama M, Yuzawa Y, Sawai A, Matsuo S, Weening JJ, Aten J, Expression patterns of connective tissue growth factor and of TGF-beta isoforms during glomerular injury recapitulate glomerulogenesis. AM J PHYSIOL-RENAL 2010;299 (3):F545-F558 [PubMed]
  • Kroening S, Neubauer E, Wullich B, Aten J, Goppelt-Struebe M, Characterization of connective tissue growth factor expression in primary cultures of human tubular epithelial cells: modulation by hypoxia. AM J PHYSIOL-RENAL 2010;298 (3):F796-F806 [PubMed]
  • Mizutani M, Ito Y, Mizuno M, Nishimura H, Suzuki Y, Hattori R, Matsukawa Y, Imai M, Oliver N, Goldschmeding R, Aten J, Krediet RT, Yuzawa Y, Matsuo S, Connective tissue growth factor (CTGF/CCN2) is increased in peritoneal dialysis patients with high peritoneal solute transport rate. AM J PHYSIOL-RENAL 2010;298 (3):F721-F733 [PubMed]
  • Witte MD, Kallemeijn WW, Aten J, Li KY, Strijland A, Donker-Koopman WE, van den Nieuwendijk AMCH, Bleijlevens B, Kramer G, Florea BI, Hooibrink B, Hollak CEM, Ottenhoff R, Boot RG, van der Marel GA, Overkleeft HS, Aerts JMFG, Ultrasensitive in situ visualization of active glucocerebrosidase molecules. NAT CHEM BIOL 2010;6 (12):907-913 [PubMed]

2009

  • Bijl N, Sokolović M, Vrins C, Langeveld M, Moerland PD, Ottenhoff R, van Roomen CPAA, Claessen N, Boot RG, Aten J, Groen AK, Aerts JMFG, van Eijk M, Modulation of Glycosphingolipid Metabolism Significantly Improves Hepatic Insulin Sensitivity and Reverses Hepatic Steatosis in Mice. HEPATOLOGY 2009;50 (5):1431-1441 [PubMed]
  • van Eijk M, Aten J, Bijl N, Ottenhoff R, van Roomen CPAA, Dubbelhuis PF, Seeman I, Ghauharali-van der Vlugt K, Overkleeft HS, Arbeeny C, Groen AK, Aerts JMFG, Reducing Glycosphingolipid Content in Adipose Tissue of Obese Mice Restores Insulin Sensitivity, Adipogenesis and Reduces Inflammation. PLOS ONE 2009;4 (3):e4723 [PubMed]

2008

  • Nguyen TQ, Roestenberg P, van Nieuwenhoven FA, Bovenschen N, Li Z, Xu L, Oliver N, Aten J, Joles JA, Vial C, Brandan E, Lyons KM, Goldschmeding R, CTGF Inhibits BMP-7 Signaling in Diabetic Nephropathy. J AM SOC NEPHROL 2008;19 (11):2098-2107 [PubMed]

2007

  • Aerts JM, Ottenhoff R, Powlson AS, Grefhorst A, van Eijk M, Dubbelhuis PF, Aten J, Kuipers F, Serlie MJ, Wennekes T, Sethi JK, O'Rahilly S, Overkleeft HS, Pharmacological inhibition of glucosylceramide synthase enhances insulin sensitivity. DIABETES 2007;56 (5):1341-1349 [PubMed]
  • Celie JWAM, Rutjes NWP, Keuning ED, Soininen R, Heljasvaara R, Pihlajaniemi T, Dräger AM, Zweegman S, Kessler FL, Beelen RHJ, Florquin S, Aten J, van den Born J, Subendothelial heparan sulfate proteoglycans become major L-selectin and monocyte chemoattractant protein-1 ligands upon renal ischemia/reperfusion. AM J PATHOL 2007;170 (6):1865-1878 [PubMed]
  • van Westrhenen R, Aten J, Hajji N, de Boer OJ, Kunne C, de Waart DR, Krediet RT, Cyclosporin A induces peritoneal fibrosis and angiogenesis during chronic peritoneal exposure to a glucose-based, lactate-buffered dialysis solution in the rat. BLOOD PURIFICAT 2007;25 (5-6):466-472 [PubMed]

2006

  • Roestenberg P, van Nieuwenhoven FA, Joles JA, Trischberger C, Martens PP, Oliver N, Aten J, Höppener JW, Goldschmeding R, Temporal expression profile and distribution pattern indicate a role of connective tissue growth factor (CTGF/CCN-2) in diabetic nephropathy in mice. AM J PHYSIOL-RENAL 2006;290 (6):F1344-F1354 [PubMed]
  • Smeets B, Steenbergen MLM, Dijkman HBPM, Verrijp KN, te Loeke NAJM, Aten J, Steenbergen EJ, Wetzels JFM, Angiotensin converting enzyme inhibition prevents development of collapsing focal segmental glomerulosclerosis in Thy-1.1 transgenic mice. NEPHROL DIAL TRANSPL 2006;21 (11):3087-3097 [PubMed]
  • van den Hoven MJ, Rops AL, Bakker MA, Aten J, Rutjes N, Roestenberg P, Goldschmeding R, Zcharia E, Vlodavsky I, van der Vlag J, Berden JH, Increased expression of heparanase in overt diabetic nephropathy. KIDNEY INT 2006;70 (12):2100-2108 [PubMed]

2005

  • Brinkman J, Wijburg FA, Hollak CE, Groener JE, Verhoek M, Scheij S, Aten J, Boot RG, Aerts JM, Plasma chitotriosidase and CCL18: Early biochemical surrogate markers in type B Niemann-Pick disease. J INHERIT METAB DIS 2005;28 (1):13-20 [PubMed]
  • Nauta AJ, de Haij S, Bottazzi B, Mantovani A, Borrias MC, Aten J, Rastaldi MP, Daha MR, van Kooten C, Roos A, Human renal epithelial cells produce the long pentraxin PTX3. KIDNEY INT 2005;67 (2):543-553 [PubMed]
  • van Westrhenen R, Aten J, Aberra M, Dragt CAM, Deira G, Krediet RT, Effects of inhibition of the polyol pathway during chronic peritoneal exposure to a dialysis solution. PERITON DIALYSIS INT 2005;25 (Suppl. 3):S18-S21 [PubMed]

2004

  • Kanemoto K, Usui J, Nitta K, Horita S, Harada A, Koyama A, Aten J, Nagata M, In situ expression of connective tissue growth factor in human crescentic glomerulonephritis. VIRCHOWS ARCH 2004;444 (3):257-263 [PubMed]
  • Rouschop KMA, Sewnath ME, Claessen N, Roelofs JJTH, Hoedemaeker I, van der Neut R, Aten J, Pals ST, Weening JJ, Florquin S, CD44 deficiency increases tubular damage but reduces renal fibrosis in obstructive nephropathy. J AM SOC NEPHROL 2004;15 (3):674-686 [PubMed]
  • van den Berg JG. Immune-mediated podocyte injury and the idiopathic nephrotic syndrome. S.l.: s.n.; 2004. 97p. ISBN 90-9018524-0 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Weening JJ; copromotor(s): Aten J)
  • van der Straaten HM, Canninga-van Dijk MR, Verdonck LF, Castigliego D, Borst HPE, Aten J, Fijnheer R, Extra-domain-A fibronectin: a new marker of fibrosis in cutaneous graft-versus-host disease. J INVEST DERMATOL 2004;123 (6):1057-1062 [PubMed]

2003

  • Kanemoto K, Usui J, Tomari S, Yokoi H, Mukoyama M, Aten J, Weening JJ, Nagata M, Connective tissue growth factor participates in scar formation of crescentic glomerulonephritis. LAB INVEST 2003;83 (11):1615-1625 [PubMed]
  • Lam S, van der Geest RN, Verhagen NAM, van Nieuwenhoven FA, Blom IE, Aten J, Goldschmeding R, Daha MR, van Kooten C, Connective tissue growth factor and IGF-I are produced by human renal fibroblasts and cooperate in the induction of collagen production by high glucose. DIABETES 2003;52 (12):2975-2983 [PubMed]
  • Roelofs JJTH, Rowshani AT, van den Berg JG, Claessen N, Aten J, ten Berge IJM, Weening JJ, Florquin S, Expression of urokinase plasminogen activator and its receptor during acute renal allograft rejection. KIDNEY INT 2003;64 (5):1845-1853 [PubMed]
  • Smit LA, Bende RJ, Aten J, Guikema JEJ, Aarts WM, van Noesel CJM, Expression of activation-induced cytidine deaminase is confined to B-cell non-Hodgkin's lymphomas of germinal-center phenotype. CANCER RES 2003;63 (14):3894-3898 [PubMed]
  • Spliet WGM, Aronica E, Ramkema M, Aten J, Troost D, Increased expression of connective tissue growth factor in amyotrophic lateral sclerosis human spinal cord. ACTA NEUROPATHOL 2003;106 (5):449-457 [PubMed]

2002

  • Bijl M, Dijstelbloem HM, Oost WW, Bootsma H, Derksen RHWM, Aten J, Limburg PC, Kallenberg CGM, IgG subclass distribution of autoantibodies differs between renal and extra-renal relapses in patients with systemic lupus erythematosus. RHEUMATOLOGY 2002;41 (1):62-67 [PubMed]
  • van den Berg JG, Aten J, Annink C, Ravesloot JH, Weber E, Weening JJ, Interleukin-4 and -13 promote basolateral secretion of H(+) and cathepsin L by glomerular epithelial cells. AM J PHYSIOL-RENAL 2002;282 (1):F26-F33 [PubMed]

2001

  • Blom IE, van Dijk AJ, Wieten L, Duran K, Ito Y, Kleij L, deNichilo M, Rabelink TJ, Weening JJ, Aten J, Goldschmeding R, In vitro evidence for differential involvement of CTGF, TGFbeta, and PDGF-BB in mesangial response to injury. NEPHROL DIAL TRANSPL 2001;16 (6):1139-1148 [PubMed]
  • Dammers PM, Bun JC, Bellon B, Kroese FG, Aten J, Bos NA, Immunoglobulin VH-gene usage of autoantibodies in mercuric chloride-induced membranous glomerulopathy in the rat. IMMUNOLOGY 2001;103 (2):199-209 [PubMed]
  • Florquin S, Roos A, Groothoff JW, Claessen N, van Gijlswijk-Janssen DJ, Aten J, Davin JC, Weening JJ, Severe non-proliferative lupus nephritis with predominant sub-endothelial IgA deposits. NEPHROL DIAL TRANSPL 2001;16 (7):1479-1482 [PubMed]
  • Ito Y, Goldschmeding R, Bende R, Claessen N, Chand M, Kleij L, Rabelink T, Weening J, Aten J, Kinetics of connective tissue growth factor expression during experimental proliferative glomerulonephritis. J AM SOC NEPHROL 2001;12 (3):472-484 [PubMed]
  • Roos A, Neeft M, Engelen L, Schilder-Tol EJ, Kunzendorf U, Weening JJ, Aten J, The immune dysregulatory compound mercuric chloride induces integrin-mediated T-lymphocyte adhesion. IMMUNOLOGY 2001;102 (1):31-38 [PubMed]
  • van Kooij M, de Groot K, van Vugt H, Aten J, Snoek M, Genotype versus phenotype: conflicting results in mapping a lung tumor susceptibility locus to the G7c recombination interval in the mouse MHC class III region. IMMUNOGENETICS 2001;53 (8):656-661 [PubMed]

2000

  • Aten J, Roos A, Claessen N, Schilder-Tol EJ, ten Berge IJ, Weening JJ, Strong and selective glomerular localization of CD134 ligand and TNF receptor-1 in proliferative lupus nephritis. J AM SOC NEPHROL 2000;11 (8):1426-1438 [PubMed]
  • de Vree JM, Ottenhoff R, Bosma PJ, Smith AJ, Aten J, Oude Elferink RP, Correction of liver disease by hepatocyte transplantation in a mouse model of progressive familial intrahepatic cholestasis. GASTROENTEROLOGY 2000;119 (6):1720-1730 [PubMed]
  • Goldschmeding R, Aten J, Ito Y, Blom I, Rabelink T, Weening JJ, Connective tissue growth factor: just another factor in renal fibrosis?. NEPHROL DIAL TRANSPL 2000;15 (3):296-299 [PubMed]
  • van den Berg JG, Aten J, Chand MA, Claessen N, Dijkink L, Wijdenes J, Lakkis FG, Weening JJ, Interleukin-4 and interleukin-13 act on glomerular visceral epithelial cells. J AM SOC NEPHROL 2000;11 (3):413-422 [PubMed]
  • van den Wijngaard RM, Aten J, Scheepmaker A, Le Poole IC, Tigges AJ, Westerhof W, Das PK, Expression and modulation of apoptosis regulatory molecules in human melanocytes: significance in vitiligo. BRIT J DERMATOL 2000;143 (3):573-581 [PubMed]

1998

  • de Vree JM, Jacquemin E, Sturm E, Cresteil D, Bosma PJ, Aten J, Deleuze JF, Desrochers M, Burdelski M, Bernard O, Oude Elferink RP, Hadchouel M, Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis. P NATL ACAD SCI USA 1998;95 (1):282-287 [PubMed]
  • Ito Y, Aten J, Bende RJ, Oemar BS, Rabelink TJ, Weening JJ, Goldschmeding R, Expression of connective tissue growth factor in human renal fibrosis. KIDNEY INT 1998;53 (4):853-861 [PubMed]
  • Roos A, Claessen N, Schilder-Tol EJ, Weening JJ, Aten J, Differential expression of T-cell adhesion molecules and LFA-1-dependent intercellular adhesion in HgCl2-induced autoimmunity and immune suppression. SCAND J IMMUNOL 1998;48 (4):389-396 [PubMed]
  • Roos A, Schilder-Tol EJ, Chand MA, Claessen N, Lakkis FG, Pascual DW, Weening JJ, Aten J, Differential regulation of expression of the MHC class II molecules RT1.B and RT1.D on rat B lymphocytes: effects of interleukin-4, interleukin-13 and interferon-gamma. IMMUNOLOGY 1998;93 (1):33-40 [PubMed]
  • Roos A, Schilder-Tol EJ, Weening JJ, Aten J, Strong expression of CD134 (OX40), a member of the TNF receptor family, in a T helper 2-type cytokine environment. J LEUKOCYTE BIOL 1998;64 (4):503-510 [PubMed]
  • Wever PC, Aten J, Rentenaar RJ, Hack CE, Koopman G, Weening JJ, ten Berge IJ, Apoptotic tubular cell death during acute renal allograft rejection. CLIN NEPHROL 1998;49 (1):28-34 [PubMed]

1997

  • Roos A, Claessen N, Schilder-Tol EJ, Chand MA, Weening JJ, Aten J, Thiol levels in CD134-defined subsets of rat T lymphocytes: possible implications for HgCl2-induced immune dysregulation. BIOCHEM BIOPH RES CO 1997;240 (2):452-457 [PubMed]
  • Roos A, Schilder-Tol EJ, Chand MA, Weening JJ, Aten J, HgCl2 and IL4 differentially modify expression of major histocompatibility complex class II molecules RT1.B and RT1.D in B lymphocytes from brown Norway and Lewis rats. TRANSPL P 1997;29 (3):1675-1676 [PubMed]

1996

  • Roos A, Claessen N, Weening JJ, Aten J, Enhanced T lymphocyte expression of LFA-1, ICAM-1, and the TNF receptor family member OX40 in HgCl2-induced systemic autoimmunity. SCAND J IMMUNOL 1996;43 (5):507-518 [PubMed]

1995

  • Aten J, Prigent P, Poncet P, Blanpied C, Claessen N, Druet P, Hirsch F, Mercuric chloride-induced programmed cell death of a murine T cell hybridoma. I. Effect of the proto-oncogene Bcl-2. CELL IMMUNOL 1995;161 (1):98-106 [PubMed]
  • Aten J, Veninga A, Coers W, Sonnenberg A, Timpl R, Claessen N, van Eendenburg JD, de Heer E, Weening JJ, Autoantibodies to the laminin P1 fragment in HgCl2-induced membranous glomerulopathy. AM J PATHOL 1995;146 (6):1467-1480 [PubMed]
  • Prigent P, Poncet P, Aten J, Blanpied C, Chand A, Février M, Druet P, Hirsch F, Mercuric chloride-induced programmed cell death of a murine T cell hybridoma. II. Opposite effect of interleukin-2 and interleukin-4. CELL IMMUNOL 1995;161 (1):107-111 [PubMed]
  • Troost D, Aten J, Morsink F, de Jong JM, Apoptosis in ALS is not restricted to motoneurons: Bcl-2 expression is increased in post-central cortex, adjacent to the affected motor cortex. J NEUROL SCI 1995;129 (Suppl):79-80 [PubMed]
  • Troost D, Aten J, Morsink F, de Jong JM, Apoptosis in amyotrophic lateral sclerosis is not restricted to motor neurons. Bcl-2 expression is increased in unaffected post-central gyrus. NEUROPATH APPL NEURO 1995;21 (6):498-504 [PubMed]
  • van der Meide PH, de Labie MC, Botman CA, Aten J, Weening JJ, Nitric oxide suppresses IFN-gamma production in the spleen of mercuric chloride-exposed brown Norway rats. CELL IMMUNOL 1995;161 (2):195-206 [PubMed]
  • van der Meide PH, Groenestein RJ, de Labie MC, Aten J, Weening JJ, Susceptibility to mercuric chloride-induced glomerulonephritis is age-dependent: study of the role of IFN-gamma. CELL IMMUNOL 1995;162 (1):131-137 [PubMed]

1993

  • Prigent P, Blanpied C, Aten J, Hirsch F, A safe and rapid method for analyzing apoptosis-induced fragmentation of DNA extracted from tissues or cultured cells. J IMMUNOL METHODS 1993;160 (1):139-140 [PubMed]
  • van der Meide PH, de Labie MC, Botman CA, van Bennekom WP, Olsson T, Aten J, Weening JJ, Mercuric chloride down-regulates T cell interferon-gamma production in brown Norway but not in Lewis rats; role of glutathione. EUR J IMMUNOL 1993;23 (3):675-681 [PubMed]

1992

  • Aten J, Stet RJ, Wagenaar-Hilbers JP, Weening JJ, Fleuren GJ, Nieuwenhuis P, Glomerulopathy induced by graft-versus-host reaction in the rat. Requirement of donor CD4+ T lymphocytes and MHC class II incompatibility at the lymphoid compartment. SCAND J IMMUNOL 1992;35 (1):93-105 [PubMed]
  • Aten J, Veninga A, Bruijn JA, Prins FA, de Heer E, Weening JJ, Antigenic specificities of glomerular-bound autoantibodies in membranous glomerulopathy induced by mercuric chloride. CLIN IMMUNOL IMMUNOPATHOL 1992;63 (1):89-102 [PubMed]

1991

  • Aten J, Veninga A, de Heer E, Rozing J, Nieuwenhuis P, Hoedemaeker PJ, Weening JJ, Susceptibility to the induction of either autoimmunity or immunosuppression by mercuric chloride is related to the major histocompatibility complex class II haplotype. EUR J IMMUNOL 1991;21 (3):611-616 [PubMed]
  • Hoedemaeker PJ, Aten J, Hogendoorn PC, Kawasaki K, van Leer EH, de Heer E, Fleuren GJ, Pathogenesis of glomerulonephritis: experimental models revisited. ADV NEPHROL NECKER HOSP 1991;20:73-90 [PubMed]

1988

  • Aten J, Bosman CB, de Heer E, Hoedemaeker PJ, Weening JJ, Cyclosporin A induces long-term unresponsiveness in mercuric chloride-induced autoimmune glomerulonephritis. CLIN EXP IMMUNOL 1988;73 (2):307-311 [PubMed]
  • Aten J, Bosman CB, Rozing J, Stijnen T, Hoedemaeker PJ, Weening JJ, Mercuric chloride-induced autoimmunity in the brown Norway rat. Cellular kinetics and major histocompatibility complex antigen expression. AM J PATHOL 1988;133 (1):127-138 [PubMed]

1985

  • Kroese FG, Opstelten D, Wubbena AS, Deenen GJ, Aten J, Schwander EH, de Leij L, Nieuwenhuis P, Monoclonal antibodies to rat B lymphocyte (sub-)populations. ADV EXP MED BIOL 1985;186:81-89 [PubMed]