Dr. M.E. Doorenspleet MSc publications

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Publications Dr. M.E. Doorenspleet MSc

Position
PhD student
Main activities
Research
Specialisation
B-cell receptor repertoires in (auto)immunity
Focus of research

B-cell receptor repertoires in (auto)immunity

The genetics of rheumatoid arthritis

2018

  • Musters A, Klarenbeek PL, Doorenspleet ME, Balzaretti G, Esveldt REE, van Schaik BDC, Jongejan A, Tas SW, van Kampen AHC, Baas F, de Vries N, In Rheumatoid Arthritis, Synovitis at Different Inflammatory Sites Is Dominated by Shared but Patient-Specific T Cell Clones. J IMMUNOL 2018;201 (2):417-422 [PubMed]
  • Roos E, Hubers LM, Coelen RJS, Doorenspleet ME, de Vries N, Verheij J, Beuers U, van Gulik TM, IgG4-Associated Cholangitis in Patients Resected for Presumed Perihilar Cholangiocarcinoma: a 30-Year Tertiary Care Experience. AM J GASTROENTEROL 2018;113 (5):765-772 [PubMed]
  • Visser A, Doorenspleet ME, de Vries N, Spijkervet FKL, Vissink A, Bende RJ, Bootsma H, Kroese FGM, Bos NA, Acquisition of N-Glycosylation Sites in Immunoglobulin Heavy Chain Genes During Local Expansion in Parotid Salivary Glands of Primary Sjögren Patients. FRONT IMMUNOL 2018;9:491 [PubMed]

2017

  • Doorenspleet ME. Standing out of the crowd: Adaptive immune cells in the pathogenesis and prediction of rheumatoid arthritis and IgG4-related disease. S.l.: s.n.; 2017. 194p. ISBN 9789462336278 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Tak PP, Baas F; copromotor(s): de Vries N, Beuers UHW)
  • Doorenspleet ME , Westera L, Peters CP, Hakvoort TBM, Esveldt RE, Vogels E, van Kampen AHC, Baas F, Buskens C, Bemelman WA, D'Haens G, Ponsioen CY, te Velde AA, de Vries N, van den Brink GR, Profoundly Expanded T-cell Clones in the Inflamed and Uninflamed Intestine of Patients With Crohn's Disease. J CROHNS COLITIS 2017;11 (7):831-839 [PubMed]
  • Reshetova P, van Schaik BDC, Klarenbeek PL, Doorenspleet ME, Esveldt REE, Tak PP, Guikema JEJ, de Vries N, van Kampen AHC, Computational Model Reveals Limited Correlation between Germinal Center B-Cell Subclone Abundancy and Affinity: Implications for Repertoire Sequencing. FRONT IMMUNOL 2017;8:221 [PubMed]
  • Tak PP, Doorenspleet ME, de Hair MJH, Klarenbeek PL, van Beers-Tas MH, van Kampen AHC, van Schaardenburg D, Gerlag DM, Baas F, de Vries N, Dominant B cell receptor clones in peripheral blood predict onset of arthritis in individuals at risk for rheumatoid arthritis. ANN RHEUM DIS 2017;76 (11):1924-1930 [PubMed]

2016

  • Doorenspleet ME, Hubers LM, Culver EL, Maillette de Buy Wenniger LJ, Klarenbeek PL, Chapman RW, Baas F, van de Graaf SF, Verheij J, van Gulik TM, Barnes E, Beuers U, de Vries N, Immunoglobulin G4(+) B-cell receptor clones distinguish immunoglobulin G 4-related disease from primary sclerosing cholangitis and biliary/pancreatic malignancies. HEPATOLOGY 2016;64 (2):501-507 [PubMed]

2015

  • Beuers U, Hubers LM, Doorenspleet M, Maillette de Buy Wenniger L, Klarenbeek PL, Boonstra K, Ponsioen C, Rauws E, de Vries N, IgG4-Associated Cholangitis--A Mimic of PSC. DIGEST DIS 2015;33 (Suppl. 2):176-180 [PubMed]
  • Hubers LM, Maillette de Buy Wenniger LJ, Doorenspleet ME, Klarenbeek PL, Verheij J, Rauws EA, van Gulik TM, Oude Elferink RPJ, van de Graaf SFJ, de Vries N, Beuers U, IgG4-associated cholangitis: a comprehensive review. CLIN REV ALLERG IMMU 2015;48 (2-3):198-206 [PubMed]
  • Klarenbeek PL, Doorenspleet ME, Esveldt REE, van Schaik BDC, Lardy N, van Kampen AHC, Tak PP, Plenge RM, Baas F, de Bakker PIW, de Vries N, Somatic Variation of T-Cell Receptor Genes Strongly Associate with HLA Class Restriction. PLOS ONE 2015;10 (10):e0140815 [PubMed]
  • Remmerswaal EBM, Klarenbeek PL, Alves NL, Doorenspleet ME, van Schaik BDC, Esveldt REE, Idu MM, van Leeuwen EMM, van der Bom-Baylon N, van Kampen AHC, Koch SD, Pircher H, Bemelman FJ, ten Brinke A, Baas F, ten Berge IJM, van Lier RAW, de Vries N, Clonal evolution of CD8+ T cell responses against latent viruses: relationship among phenotype, localization, and function. J VIROL 2015;89 (1):568-580 [PubMed]

2014

  • Beuers U, Maillette de Buy Wenniger LJ, Doorenspleet M, Hubers L, Verheij J, van Gulik T, van de Graaf SFJ, de Vries N, IgG4-associated cholangitis. DIGEST DIS 2014;32 (5):605-608 [PubMed]
  • Doorenspleet ME , Klarenbeek PL, de Hair MJH, van Schaik BDC, Esveldt REE, van Kampen AHC, Gerlag DM, Musters A, Baas F, Tak PP, de Vries N, Rheumatoid arthritis synovial tissue harbours dominant B-cell and plasma-cell clones associated with autoreactivity. ANN RHEUM DIS 2014;73 (4):756-762 [PubMed]
  • van Schaik B, Klarenbeek P, Doorenspleet M, van Kampen A, Moody DB, de Vries N, van Rhijn I, Discovery of invariant T cells by next-generation sequencing of the human TCR α-chain repertoire. J IMMUNOL 2014;193 (10):5338-5344 [PubMed]

2013

  • Cui J, Stahl EA, Saevarsdottir S, Miceli C, Diogo D, Trynka G, Raj T, Mirkov MU, Canhao H, Ikari K, Terao C, Okada Y, Wedrén S, Askling J, Yamanaka H, Momohara S, Taniguchi A, Ohmura K, Matsuda F, Mimori T, Gupta N, Kuchroo M, Morgan AW, Isaacs JD, Wilson AG, Hyrich KL, Herenius M, Doorenspleet ME, Tak PP, Crusius JBA, van der Horst-Bruinsma IE, Wolbink GJ, van Riel PLCM, van de Laar M, Guchelaar HJ, Shadick NA, Allaart CF, Huizinga TWJ, Toes REM, Kimberly RP, Bridges SL Jr, Criswell LA, Moreland LW, Fonseca JE, de Vries N, Stranger BE, de Jager PL, Raychaudhuri S, Weinblatt ME, Gregersen PK, Mariette X, Barton A, Padyukov L, Coenen MJH, Karlson EW, Plenge RM, Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis. PLOS GENET 2013;9 (3):e1003394 [PubMed]
  • Maillette de Buy Wenniger LJ, Doorenspleet ME, Klarenbeek PL, Verheij J, Baas F, Elferink RPO, Tak PP, de Vries N, Beuers U, Immunoglobulin G4+ clones identified by next-generation sequencing dominate the B cell receptor repertoire in immunoglobulin G4 associated cholangitis. HEPATOLOGY 2013;57 (6):2390-2398 [PubMed]
  • Maillette de Buy Wenniger LJ, Doorenspleet ME, Verheij J, de Vries N, Beuers U, IgG4-gerelateerde ziekte. NED TIJDSCHR GENEESKD 2013;157 (46):A6476 [PubMed]
  • Plenge RM, Greenberg JD, Mangravite LM, Derry JMJ, Stahl EA, Coenen MJH, Barton A, Padyukov L, Klareskog L, Gregersen PK, Mariette X, Moreland LW, Bridges SL Jr, de Vries N, Huizinga TWJ, Guchelaar HJ, Friend SH, Stolovitzky G [Contributors: Cui J, Stahl EA, Saevarsdottir S, Miceli C, Diogo D, Mirkov NN, Canhao H, Ikari K, Terao C, Okada Y, Wedri S, Askling J, Yamanaka H, Momohara S, Taniguchi A, Ohmura K, Matsuda F, Mimori T, Gupta N, Kuchroo M, Morgan AW, Isaacs JD, Wilson AG, Hyrich KL, Herenius M, Doorenspleet ME, Tak PP, Crusius JBA, van der Horst-Bruinsma IE, Wolbink GJ, van Riel PLCM, van de Laar M, Guchelaar HJ, Shadick NA, Allaart CF, Huizinga TWJ, Toes REM, Kimberly RP, Bridges SL Jr, Criswell LA, Moreland LW, Fonseca E, de Vries N, Raychaudhuri S, Weinblatt ME, Gregersen PK, Mariette X, Barton A, Alfredsson L, Klareskog L, Padyukov L, Coenen MJH, Karlson EW, Kremer J, Greenberg JD, Plenge RM]] , Crowdsourcing genetic prediction of clinical utility in the Rheumatoid Arthritis Responder Challenge. NAT GENET 2013;45 (5):468-469 [PubMed]
  • van Rhijn I, Kasmar A, de Jong A, Gras S, Bhati M, Doorenspleet ME, de Vries N, Godfrey DI, Altman JD, de Jager W, Rossjohn J, Moody DB, A conserved human T cell population targets mycobacterial antigens presented by CD1b. NAT IMMUNOL 2013;14 (7):706-713 [PubMed]

2012

  • Cantaert T, Doorenspleet ME, Francosalinas G, Paramarta JE, Klarenbeek PL, Tiersma Y, van der Loos CM, de Vries N, Tak PP, Baeten DL, Increased numbers of CD5+ B lymphocytes with a regulatory phenotype in spondylarthritis. ARTHRITIS RHEUM-US 2012;64 (6):1859-1868 [PubMed]
  • Klarenbeek PL, de Hair MJH, Doorenspleet ME , van Schaik BDC, Esveldt REE, van de Sande MGH, Cantaert T, Gerlag DM, Baeten D, van Kampen AHC, Baas F, Tak PP, de Vries N, Inflamed target tissue provides a specific niche for highly expanded T-cell clones in early human autoimmune disease. ANN RHEUM DIS 2012;71 (6):1088-1093 [PubMed]
  • Klarenbeek PL, Remmerswaal EBM, ten Berge IJM, Doorenspleet ME , van Schaik BDC, Esveldt REE, Koch SD, ten Brinke A, van Kampen AHC, Bemelman FJ, Tak PP, Baas F, de Vries N, van Lier RAW, Deep sequencing of antiviral T-cell responses to HCMV and EBV in humans reveals a stable repertoire that is maintained for many years. PLOS PATHOG 2012;8 (9):e1002889 [PubMed]