Dr. P.B. Lirk MSc publications

foto

Publications Dr. P.B. Lirk MSc

Position
Scientific staff member (UD)
Main activities
Patient care, Research
Specialisation
Anesthesiology
Focus of research

Regional Anesthesia and Pain Medicine

- Neurotoxicity of local anaesthetics

- Epigenetic effects of anaesthetic drugs

- Regional anesthesia in patients with diabetic neuropathy

- (Sono-) Anatomy for regional anesthesia

- Coordinating investigator PLATA study (ESA Clinical Trials Network)

 

Technology in Anesthesia

- Local Coordinator, Multicentre Perioperative Outcomes Group (MPOG)

 

 

2019

  • Ridderikhof ML , de Kruif E, Stevens MF, Baumann HM, Lirk PB, Goslings JC, Hollmann MW, Ultrasound guided supra-inguinal Fascia Iliaca Compartment Blocks in hip fracture patients: An alternative technique. AM J EMERG MED 2019;ahead of print [PubMed]

2018

  • Bos EME, Haumann J, de Quelerij M, Vandertop WP, Kalkman CJ, Hollmann MW, Lirk P, Haematoma and abscess after neuraxial anaesthesia: a review of 647 cases. BRIT J ANAESTH 2018;120 (4):693-704 [PubMed]
  • Bos EME, Schut ME, de Quelerij M, Kalkman CJ, Hollmann MW, Lirk P, Trends in practice and safety measures of epidural analgesia: Report of a national survey. ACTA ANAESTH SCAND 2018;62 (10):1466-1472 [PubMed]
  • Hulst AH, Polderman JAW, Kooij FO, Vittali D, Lirk P, Hollmann MW, DeVries JH, Preckel B, Hermanides J, Comparison of perioperative glucose regulation in patients with type 1 vs type 2 diabetes mellitus: A retrospective cross-sectional study. ACTA ANAESTH SCAND 2018;ahead of print [PubMed]
  • Kirmeier E, Eriksson LI, Lewald H, Jonsson Fagerlund M, Hoeft A, Hollmann M, Meistelman C, Hunter JM, Ulm K, Blobner M [Contributors: Leva B, Harlet P, Feijten P, Damster S, Blobner M, Eriksson LI, Hollmann M, Hunter J, Jonsson Fagerlund M, Kirmeier E, Lewald H, Meistelman C, Ulm K, Dum E, Von Lutterotti T, Köstenberger M, Lercher H, Neuwersch S, Knotzer J, Kotzinger O, Gferer G, Pitterle M, Sparr H, Berger MM, Danninger T, Kopp K, Kunit C, Ausserer J, Hoelbling D, Khuenl-Brady K, Paal P, Pehboeck D, Potocnik M, Smitz C, Vercauteren M, Verheyen V, Cammu G, Gavranović Z, Maldini B, Goranović T, Klancir T, Kovačević M, Markić A, Mazul Sunko B, Nesek Adam V, Milić M, Sojčić N, Vitković B, Nováková A, Večeřa L, Harazim H, Kosinová M, Smékalová O, Štourač P, Dzurňáková P, Lišková K, Volfová I, Afshari A, Ekelund K, Elme A, Karjagin J, Sõrmus A, Toim H, Junke E, Allaouchiche B, Boselli E, Bouvet L, Danguy des Déserts M, Nguyen BV, Pardey Bracho GF, Saby S, Bois G, Leuvrey M, Mathis C, Moeglen A, Philippe S, Scalco L, Schmidt-Mutter C, Stoerckel M, Carise E, Debaene B, Frasca D, Ernst T, Gottschalk A, V Tiesenhausen A, Rueffert H, Baumüller E, Foerster U, Ripke F, Stäuble C, Lipski F, Luippold M, Roth W, Rupprecht K, Schmidt-Ehrenberg F, Zucker TP, Bergmann N, Bischoff P, Mittelstädt L, Wallner J, Buerkle H, Goebel U, Kaufmann K, Pohl H, Rotter MT, Spaeth J, Wirth S, Zachoval C, Schax C, Spielmann A, Standl T, Feggeler J, Bankewitz C, Baumgarten G, Ellerkmann R, Fellmann T, Fleischer A, Günther U, Guttenthaler V, Hack Y, Hoeft A, Kirchgäßner K, Männer O, Marchand B, Schurig M, Struck R, van Zyl R, Weber S, Wittmann M, Kranke P, Kranke E, Balandin A, Kraus S, Kraus C, Metterlein T, Schönberg C, Unterbuchner C, Werkmann M, Ziegleder R, Gkinas D, Oloktsidou E, Papapostolou K, Tsaousi G, Gkiokas G, Stamelos M, Theodoraki K, Stroumpoulis K, Valsamidis D, Mavrommati E, Tanou V, Tsiftsi A, Vassilakis G, Katsika E, Korfiotis D, Serchan P, Chatzimicali A, Papaioannou A, Syrogianni P, Batistaki C, Kyttari A, Matsota P, Buggy D, Prchalova M, Ní Eochagáin A, Keane H, Darwish I, Elghouty E, Toninelli A, Bucolo GE, Monea MC, Vicari Sottosanti LG, Barletti V, Bonicolini E, Gambino I, Meli A, Romagnoli S, Stera C, Campesato M, Copeta F, Di Giacinto I, Melotti RM, Sorella MC, Toni J, Vecchiatini T, Vissicchio D, Fullin G, Grassetto A, Serafini E, Zampieri S, Gambale G, Malewski G, Morri D, Tartaglione M, Ciardo S, Taddei S, Corso RM, Gioia A, Legrottaglie AM, Maitan S, Zampone S, Bifulco F, Cascella M, Cuomo A, Maciariello M, Pota V, Schiavone V, Aletti G, Amigoni M, Butturini F, Giovannoni C, Mokini Z, Pesenti A, Vitale G, Baiardo Redaelli M, Bellandi M, Belletti A, Beretta L, Bignami E, Casiraghi GM, Febres D, Guarnieri M, Landoni G, Manfredini L, Martino EA, Nardelli P, Pasin L, Saleh O, Spada A, Zambon M, Zangrillo A, Barbera F, Cricca V, Orlando A, Ragazzi R, Spadaro S, Verri M, Volta CA, Fusari M, Mescolini S, Negri M, Terenzoni M, Zani G, Carrieri C, Montillo G, Nardin G, Lorenzini L, Brazzi L, Floris L, Liperi C, Pistidda L, Sales G, Cinnella G, Lombardi FS, Menga MR, Mirabella L, Petta R, Di Mauro P, Fumagalli J, Marrazzo F, Tommasino C, Cortegiani A, Giarratano A, Montalto F, Raineri SM, Russotto V, Brazzoni M, de Flaviis A, Deana C, Della Rocca G, Pompei L, Toretti I, Vilardi A, Guadagnin GM, Gecaj-Gashi A, Hashimi M, Katanolli F, Baliuliene V, Bernotaite M, Bilskiene D, Bubliauskas A, Bukauskas T, Karbonskiene A, Keraitiene G, Macas A, Rimaitis K, Rimaitis M, Trepenaitis D, Zavackiene A, Dimitrovski A, Kuzmanovska B, Gievski V, Radoeshki A, Shosholcheva M, Beurskens C, Eberl S, Hemmes S, Hermanides J, Hermanns H, Koers L, Kooij F, Lirk P, Polderman J, Preckel B, Wensing C, Schultz M, Stevens M, Koopman-van Gemert AWMM, Bouwman A, Koolen E, van der Beek T, Buhre WF, Kudrashou A, Schreiber JU, van Zundert T, de Boer HD, Hettiarachchi RM, Umc R, Fernando A, Scheffer GJ, Inan T, van Dasselaar N, van Poorten F, Verdouw B, Numan S, van Klei WA, van Zaane B, Boer C, van Duivenvoorde Y, van Beek R, Zonneveldt H, Hestenes S, Melbybråthen G, Rial E, Aslam T, Bjønness T, Lindholm E, Ringvold EM, Andersen E, Kummen L, Rasmussen A, Rudjord A, Feyling A, Heier T, Siamansour TS, Kanski A, Starczewska M, Borecka-Kedzierska M, Gilowska K, Gornik-Wlaszczuk E, Kucharski R, Majewski J, Borys M, Czuczwar M, Piwowarczyk P, Potreć B, Rypulak E, Sysiak J, Garlak J, Żukowski M, Calhau R, Carreteiro J, Parente S, Costa G, Cunha M, Domingues S, Marinheiro L, Moura F, Tarroso M, Vasconcelos P, Castelo-Branco L, Neves M, Pinto R, Santos S, Azevedo P, Carmona C, Oliveira I, Branco T, Casal M, Correia de Barros F, Esteves S, Ferreira L, Machado H, Madeira I, Mascarenhas C, Moreira Z, Pereira M, Pina P, Sá J, Sá Couto P, Antunes P, Assunção JP, Barros A, Ferreira P, Pereira C, Pinho-Oliveira V, Rato A, Ribeiro S, Rodrigues P, Vico M, Cernea D, Dragoescu A, Stanculescu A, Grintescu I, Mirea L, Ologoiu D, Tiganiuc L, Badarau V, Cîndea I, Cocu S, Dîrzu DS, Hagău N, Balan C, Daniliuc A, Ionităv V, Filipescu D, Paunescu A, Droc G, Stefan OM, Vaida S, Voicu A, Marcu A, Popescu M, Tomescu D, Tudor A, Badescu R, Godoroja D, Balescu-Arion C, Moise A, Dascalu C, Grigoras I, Parfeni A, Ristescu I, Cantor A, Cimpeanu L, Horhota L, Bandrabur D, Almasy E, Barsan V, Copotoiu S, Szederjesi J, Fedorov S, Galushka S, Gavrilov R, Lazarev K, Chervjakov I, Gritsan A, Gritsan G, Korolkov O, Anipchenko N, Lugovoy A, Ovezov A, Jovic M, Milojevic M, Sagic J, Unic-Stojanovic D, Dinic V, Jankovic R, Savić N, Bozić T, Popovic R, Stanisavljević S, Vukcevic D, Stošić B, Neskovic V, Rondovic G, Vukovic R, Humplíková S, Michalov M, Mráz P, Polakovičová L, Stanek O, Tarabová K, Bilic A, Kasnik D, Kompan J, Uranjek J, Wegiel Leskiewicz A, Borstnar K, Gerjevic B, Ursic T, Dolinar J, Hribar R, Zupančič D, Grynyuk A, Janez B, Jenko M, Markovič Bozič J, Marusič-Gaser K, Novak-Jankovič V, Spindler-Vesel A, Voje M, Vrecič-Slabe S, López Alvarez A, Padin Barreiro L, Sanchez Sanchez YE, Casanova I, Errando CL, Granell M, Diaz Gomez TV, Lisi A, Perez Tejero G, Vargas Munoz AM, Fernández Castineira A, Pérez Soto A, Ferrando C, Garcia-Perez ML, Miñana A, Moreno T, Pastor E, Romero E, Soro M, Cabrera Díaz I, Pérez García A, Valldeperas Ferrer S, Vidal Mitjans P, Agudelo Montoya ME, Becerra Cayetano IA, Delgado Garcia I, Moro Velasco C, Navarro Perez R, Tardaguila Sancho P, India I, Pinol S, Unzueta C, Belmonte Cuenca J, Castro Arranz C, Soler Pedrola M, Valldeperas Hernandez MI, Ayas Montero B, Lluch Oltra A, Perez Caballero P, Calderon A, Callejo A, Casero LM, Gonzalez M, Guerrero Diez M, Jimenez R, Kadaoui SD, Levstek M, Lopez Lopez E, Martin Ayuso M, Novillo M, Perez-Cerda F, Real Navacerrada MI, Vullo PA, Abad Gurumeta A, Baltasar Isabel J, Brogly N, Gilsanz Rodriguez F, Herrera Hueso B, Iannuccelli F, Suarez de la Rica A, Bermudez Lopez M, Jimenez Gomez B, Lopez Rodríguez M, Naveiro Pan A, Pico Veloso J, Ayuso M, Moreno R, de Salut Mar P, Benitez-Cano A, Fernández-Candil J, López E, Moltó L, Santiveri FX, Cervantes O, Martinez E, Moret E, Ródenas F, Ekengren P, Sem V, Smole D, Wikström E, Gillberg L, Granstrom A, Khudhur A, Oldner A, Schening A, Åslin B, Wallden J, Westberg H, Wallberg H, Andersson P, Rundgren M, Walther Sturesson L, Broms J, Divander MB, Ewaldsson C, Joelsson-Alm E, Svensén C, Byttner A, Bergmark K, Gottfridsson P, Molin A, Blokhin I, Jonikaite L, Semenas E, Alkış N, Can ÖS, Güçlü Ç, Meço BC, Turhan SÇ, Karadağ S, Baytaş V, Gunenc F, Hancı V, Kucukguclu S, Kuvaki B, Ozbilgin S, Akgün FN, Şanli Karip C, Turan G, Kabakov B, Bowen L, Frost V, Mac Gregor MG, Smee E, Blethyn K, Harris B, Rogers E, Varsani N, Wade A, Clark S, Knowlden P, Lowicka M, Ryszka M, Hua A, Loganathan V, Mrozek K, Norrie K, Vizcaychipi MP, Haldar J, Jain V, Klucniks A, Allan A, Cope S, Furneval J, Koneti KK, Palugniok R, Chinery E, Morgan M, Zsisku L, Cowton A, Limb J, Rafi A, Ramasamy R, Abigail P, Gallacher S, Hyams B, Minto G, Avvai M, Desai T, Kumar V, Thornley H, Linton F, Moreton S, Pulletz M, Richardson L, Pugh R, Shobha R, Wright S, Achaibar K, Bidd H, Blunt N, Booth J, Chondhury P, Christodoudiles G, Cronin J, Dumitrescu A, Hafisayena A, Leong M, Meier S, Rajput Z, Ramessur S, Taylor E, Trethowan B, Collyer T, Featherstone J, Moull A, Abernethy C, Balaji P, Greenwood A, Henderson K, Husnain A, Hussein A, Martinson V, Pickering D, Ramachandran R, Smith N, Sultanpori A, Debreceni G, Hales D, Hanna-Jumma S, Lau G, Rich N, Bowrey S, Girotra V, Mushambi M, Patil A, Baluch SN, Heaton J, Leonardi S, Rose BO, Christie E, Kelly M, Goel V, Saul D, Sinha A, Chishti A, Scott C, Saunders D, Sinclair R, Allan K, Baker T, Barber K, Dhillon P, Fox B, King S, Oduro-Dominah L, Reavley C, Soto C, Brohi F, Paranthaman P, Siddiqi K, Hunt J, Rousseau G, Skinner A, Stancombe L, Garg S, Barcraft-Barnes H, Camsooksai J, Colvin C, Jenkins S, Patch S, Reschreiter H, Tbaily L, Ritchie K, Nightingale J, Sinha A, Giles J, Harvey O, Nicholas C, Weller D, Hormis A, Boxall L, Curley K, Helliwell L, Ilett K, Kidd L, Nadolski M, Potter A, Telford R, Martin J, Townley S, Doolan J, Michlig S, Murthy BVS, Rushton A, Scanlon D, Gosavi S, Zuleika M, Armstrong E, Holland J, McCourt K, Montgomery C, O'Reilly R, Reid J, Shields M, Delroy-Buelles I, Gaynor J, Schopflin C, Watson D, Chandler B, Harper D, Ellis H, Sanghera S, Frey C, Adam E, Bartlett P, Beauchamp N, Blincoe T, Charnock R, Cox N, Edwards M, Hawkins L, Leggett S, McGill N, Wilson R, Mckee R, Mukhtar K, Bishop L, Gupta P, Ilyas C, Lumb A, Plotnikova O, Rao R, Singh R, Tan HE, Amey I, Baird Y, Carter A, Highgate J, Margalef J, Margarson M, Moore S, Murray H, Standley T, Allcock C, Baron K, Merotra S, Farid N, Sonksen J, Bell S, Blaylock H, Kushakovsky V, Cirstea E, Franke U, Swan L, Davies K, Edwards J, John J, Steen J, Craig J, Willett E, Wood L, Brear T, Downes C, Humphries R, Melbourne S, Rogerson D, Sarno S, Moore F, Muniyappa S, Siddaiah N, Barnett G, Bradley T, de Selincourt G, Melia A, Mercer P, Montgomery J, Awad N, Dedhia J, Joachim S, Razaque U, Hayes C, Passey S, Pramod N, Rajamanickam T, Sebestian S, Singh P, Sundara Rajan R, Williams B, Duncan L, Kent M, Sehgal S, Somanath S, Clayton M, Dabrowska D, Georghiou M, Humphreys S, Kubitzek C, Baird C, Hodgson K, Irwin F, Midgley S, Steel E, Suying O, Davies S, Gibson A, Smith T]] , Post-anaesthesia pulmonary complications after use of muscle relaxants (POPULAR): a multicentre, prospective observational study. LANCET RESP MED 2018;ahead of print [PubMed]
  • Lirk P, Hollmann MW, Strichartz G, The Science of Local Anesthesia: Basic Research, Clinical Application, and Future Directions. ANESTH ANALG 2018;126 (4):1381-1392 [PubMed]
  • Mungroop TH, Bond MJ, Lirk P, Busch OR, Hollmann MW, Veelo DP, Besselink MG, Preperitoneal or Subcutaneous Wound Catheters as Alternative for Epidural Analgesia in Abdominal Surgery: A Systematic Review and Meta-analysis. ANN SURG 2018;ahead of print [PubMed]
  • Ridderikhof ML, Lirk P, Goddijn H, Vandewalle E, Schinkel E, van Dieren S, Kemper EM, Hollmann MW, Goslings JC, Acetaminophen or Nonsteroidal Anti-Inflammatory Drugs in Acute Musculoskeletal Trauma: A Multicenter, Double-Blind, Randomized, Clinical Trial. ANN EMERG MED 2018;71 (3):357-368.e8 [PubMed]
  • ten Hoope W, Hollmann MW, de Bruin K, Verberne HJ, Verkerk AO, Tan HL, Verhamme C, Horn J, Rigaud M, Picardi S, Lirk P, Pharmacodynamics and Pharmacokinetics of Lidocaine in a Rodent Model of Diabetic Neuropathy. ANESTHESIOLOGY 2018;128 (3):609-619 [PubMed]

2017

  • Bos EME, Hollmann MW, Lirk P, Safety and efficacy of epidural analgesia. CURR OPIN ANESTHESIO 2017;30 (6):736-742 [PubMed]
  • Lee LO, Bateman BT, Kheterpal S, Klumpner TT, Housey M, Aziz MF, Hand KW, MacEachern M, Goodier CG, Bernstein J, Bauer ME [Contributors: Lirk P , Wilczak J, Soto R, Tom S, Cuff G, Biggs DA, Coffman T, Saager L, Levy WJ, Godbold M, Pace NL, Wethington KL, Paganelli WC, Durieux ME, Domino KB, Nair B, Ehrenfeld JM, Wanderer JP, Schonberger RB]] , Risk of Epidural Hematoma after Neuraxial Techniques in Thrombocytopenic Parturients A Report from the Multicenter Perioperative Outcomes Group. ANESTHESIOLOGY 2017;126 (6):1053-1064 [PubMed]
  • Mungroop TH, van Samkar G, Geerts BF, van Dieren S, Besselink MG, Veelo DP, Lirk P, Serum levels of bupivacaine after pre-peritoneal bolus vs. epidural bolus injection for analgesia in abdominal surgery: A safety study within a randomized controlled trial. PLOS ONE 2017;12 (6):e0178917 [PubMed]
  • Rahiri J, Tuhoe J, Svirskis D, Lightfoot NJ, Lirk PB, Hill AG, Systematic review of the systemic concentrations of local anaesthetic after transversus abdominis plane block and rectus sheath block. BRIT J ANAESTH 2017;118 (4):517-526 [PubMed]
  • Ridderikhof ML, Schyns FJ, Schep NW, Lirk P, Hollmann MW, Goslings JC, Emergency Department Pain Management in Adult Patients With Traumatic Injuries Before and After Implementation of a Nurse-Initiated Pain Treatment Protocol Utilizing Fentanyl for Severe Pain. J EMERG MED 2017;52 (4):417-425 [PubMed]
  • Sekandarzad MW, van Zundert AAJ, Lirk PB, Doornebal CW, Hollmann MW, Perioperative Anesthesia Care and Tumor Progression. ANESTH ANALG 2017;124 (5):1697-1708 [PubMed]
  • ten Hoope W, Hollmann MW, Atchabahian A, Rigaud M, Kerkhoffs GM, Lirk P, Baumann HM, Minimum local anesthetic volumes for a selective saphenous nerve block: a dose-finding study. MINERVA ANESTESIOL 2017;83 (2):183-190 [PubMed]
  • ten Hoope W, Looije M, Lirk P, Regional anesthesia in diabetic peripheral neuropathy. CURR OPIN ANESTHESIO 2017;30 (5):627-631 [PubMed]
  • van Beek R, Zonneveldt HJ, van der Ploeg T, Steens J, Lirk P, Hollmann MW, In patients undergoing fast track total knee arthroplasty, addition of buprenorphine to a femoral nerve block has no clinical advantage A prospective, double-blinded, randomized, placebo controlled trial. MEDICINE 2017;96 (27):e7393 [PubMed]
  • van Samkar G, Hermanns H, Lirk P, Hollmann MW, Stevens MF, Influence on number of top-ups after implementing patient controlled epidural analgesia: A cohort study. PLOS ONE 2017;12 (10):e0186225 [PubMed]

2016

  • Heschl S, Hallmann B, Zilke T, Gemes G, Schoerghuber M, Auer-Grumbach M, Quehenberger F, Lirk P, Hogan Q, Rigaud M, Diabetic neuropathy increases stimulation threshold during popliteal sciatic nerve block. BRIT J ANAESTH 2016;116 (4):538-545 [PubMed]
  • Kirchmair L, Ströhle M, Löscher WN, Kreutziger J, Voelckel WG, Lirk P, Neurophysiological effects of needle trauma and intraneural injection in a porcine model: a pilot study. ACTA ANAESTH SCAND 2016;60 (3):393-399 [PubMed]
  • Mungroop TH, Veelo DP, Busch OR, van Dieren S, van Gulik TM, Karsten TM, de Castro SM, Godfried MB, Thiel B, Hollmann MW, Lirk P, Besselink MG, Continuous wound infiltration versus epidural analgesia after hepato-pancreato-biliary surgery (POP-UP): a randomised controlled, open-label, non-inferiority trial. LANCET GASTROENTEROL HEPATOL 2016;1 (2):105-113 [PubMed]
  • Piegeler T, Hollmann MW, Borgeat A, Lirk P, Do Amide Local Anesthetics Play a Therapeutic Role in the Perioperative Management of Cancer Patients?. INT ANESTHESIOL CLIN 2016;54 (4):e17-e32 [PubMed]
  • Reina MA, Lirk P, Puigdellívol-Sánchez A, Mavar M, Prats-Galino A, Human Lumbar Ligamentum Flavum Anatomy for Epidural Anesthesia: Reviewing a 3D MR-Based Interactive Model and Postmortem Samples. ANESTH ANALG 2016;122 (3):903-907 [PubMed]
  • Ridderikhof ML, Leenders N, Goddijn H, Schep NW, Lirk P, Goslings JC, Hollmann MW, Anesthesia with topical lidocaine hydrochloride gauzes in acute traumatic wounds in triage, a pilot study. INT EMERG NURS 2016;28:25-28 [PubMed]
  • van Loon AM, Fahrenfort JJ, van der Velde B, Lirk PB, Vulink NCC, Hollmann MW, Scholte HS, Lamme VAF, NMDA Receptor Antagonist Ketamine Distorts Object Recognition by Reducing Feedback to Early Visual Cortex. CEREB CORTEX 2016;26 (5):1986-1996 [PubMed]
  • Verlinde M, Hollmann MW, Stevens MF, Hermanns H, Werdehausen R, Lirk P, Local Anesthetic-Induced Neurotoxicity. INT J MOL SCI 2016;17 (3):339 [PubMed]

2015

  • Frkovic V, Ward C, Preckel B, Lirk P, Hollmann MW, Stevens MF, Wegener JT, Influence of arm position on ultrasound visibility of the axillary brachial plexus. EUR J ANAESTH 2015;32 (11):771-780 [PubMed]
  • Lirk P. The Ligamentum Flavum in: Reina MA, de Andres JA, Hadzic A, Prats-Galino A, Sala-Blanch X, van Zundert AAJ, editors. Atlas of Functional Anatomy for Regional Anesthesia and Pain Medicine : Human Structure, Ultrastructure and 3D Reconstruction Images. New York: Springer; 2015., p. 639-650
  • Lirk P, Fiegl H, Weber NC, Hollmann MW, Epigenetics in the perioperative period. BRIT J PHARMACOL 2015;172 (11):2748-2755 [PubMed]
  • Lirk P, Verhamme C, Boeckh R, Stevens MF, ten Hoope W, Gerner P, Blumenthal S, de Girolami U, van Schaik IN, Hollmann MW, Picardi S, Effects of early and late diabetic neuropathy on sciatic nerve block duration and neurotoxicity in Zucker diabetic fatty rats. BRIT J ANAESTH 2015;114 (2):319-326 [PubMed]
  • Mungroop TH, Veelo DP, Busch OR, van Dieren S, van Gulik TM, Karsten TM, de Castro SM, Godfried MB, Thiel B, Hollmann MW, Lirk P, Besselink MG, Continuous wound infiltration or epidural analgesia for pain prevention after hepato-pancreato-biliary surgery within an enhanced recovery program (POP-UP trial): study protocol for a randomized controlled trial. TRIALS 2015;16 (1):562 [PubMed]
  • Picardi S, Lirk P, Blobner M, Schönherr ME, Hollmann MW, Adjuvanzien in der modernen Anästhesie - Magnesium. ANASTH INTENSIV NOTF 2015;50 (6):380-387 [PubMed]
  • Picardi S, Lirk P, Boeckh R, Hollmann MW, Adjuvanzien in der modernen Anästhesie - Lidocain. ANASTH INTENSIV NOTF 2015;50 (5):322-327 [PubMed]

2014

  • Lirk P. Local anesthetics: New insights into risks and benefits. S.l.: s.n.; 2014. 322p. ISBN 9789088919008 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Hollmann MW; copromotor(s): Hauck-Weber NC, Stevens MF)
  • Lirk P, Hollmann MW, Ondansetron: a new therapeutic option to attenuate postoperative cognitive dysfunction and delirium?. MINERVA ANESTESIOL 2014;80 (4):407-409 [PubMed]
  • Lirk P, Hollmann MW, Outcome after regional anesthesia: weighing risks and benefits. MINERVA ANESTESIOL 2014;80 (5):610-618 [PubMed]
  • Lirk P, Hollmann MW, Fleischer M, Weber NC, Fiegl H, Lidocaine and ropivacaine, but not bupivacaine, demethylate deoxyribonucleic acid in breast cancer cells in vitro. BRIT J ANAESTH 2014;113 (Suppl. 1):i32-i38 [PubMed]
  • Lirk P, Picardi S, Hollmann MW, Local anaesthetics: 10 essentials. EUR J ANAESTH 2014;31 (11):575-585 [PubMed]
  • McDonough J, Lirk P, QTc interval prolongation: a real concern or exaggerated threat?. GASTROENTEROL NURS 2014;37 (6):446-449 [PubMed]
  • Picardi S, Stevens MF, Hahnenkamp K, Durieux ME, Lirk P, Hollmann MW, Time-dependent modulation of muscarinic m1/m3 receptor signalling by local anaesthetics. BRIT J ANAESTH 2014;112 (2):370-379 [PubMed]

2013

  • Gemes G, Koopmeiners A, Rigaud M, Lirk P, Sapunar D, Bangaru ML, Vilceanu D, Garrison SR, Ljubkovic M, Mueller SJ, Stucky CL, Hogan QH, Failure of action potential propagation in sensory neurons: mechanisms and loss of afferent filtering in C-type units after painful nerve injury. J PHYSIOL-LONDON 2013;591 (4):1111-1131 [PubMed]
  • Lirk P, Berger R, Hollmann MW, Fiegl H, Lidocaine time- and dose-dependently demethylates deoxyribonucleic acid in breast cancer cell lines in vitro [Erratum]. BRIT J ANAESTH 2013;110 (1):165
  • Lirk P, Rutten MVH, Haller I, Stevens MF, Laudolff-Birmingham J, Hollmann M, Birmingham B, Management of the patient with diabetic peripheral neuropathy presenting for peripheral regional anesthesia: a European survey and review of literature. MINERVA ANESTESIOL 2013;79 (9):1039-1048 [PubMed]
  • Lirk P, Stadlbauer KH, Hollmann MW, ESA Clinical Trials Network 2012: PLATA--Prevention of Phantom Limb Pain After Transtibial Amputation: randomised, double-blind, controlled, multicentre trial comparing optimised intravenous pain control versus optimised intravenous pain control plus regional anaesthesia. EUR J ANAESTH 2013;30 (5):202-204 [PubMed]
  • Meuwese JDI, van Loon AM, Scholte HS, Lirk PB, Vulink NCC, Hollmann MW, Lamme VAF, NMDA receptor antagonist ketamine impairs feature integration in visual perception. PLOS ONE 2013;8 (11):e79326 [PubMed]
  • Picardi S, Cartellieri S, Groves D, Hahnenekamp K, Gerner P, Durieux ME, Stevens MF, Lirk P, Hollmann MW, Local anesthetic-induced inhibition of human neutrophil priming: the influence of structure, lipophilicity, and charge. REGION ANESTH PAIN M 2013;38 (1):9-15 [PubMed]
  • Ridderikhof ML, Lirk P, Schep NW, Hoeberichts A, Goddijn WT, Luitse JSK, Kemper EM, Dijkgraaf MGW, Hollmann MW, Goslings JC, The PanAM study: a multi-center, double-blinded, randomized, non-inferiority study of paracetamol versus non-steroidal anti-inflammatory drugs in treating acute musculoskeletal trauma. BMC EMERG MED 2013;13 (1):19 [PubMed]

2012

  • Hermanides J, Hollmann MW, Stevens MF, Lirk P, Failed epidural: causes and management. BRIT J ANAESTH 2012;109 (2):144-154 [PubMed]
  • Lirk P, Berger R, Hollmann MW, Fiegl H, Lidocaine time- and dose-dependently demethylates deoxyribonucleic acid in breast cancer cell lines in vitro. BRIT J ANAESTH 2012;109 (2):200-207 [PubMed]
  • Lirk P, Flatz M, Haller I, Hausott B, Blumenthal S, Stevens MF, Suzuki S, Klimaschewski L, Gerner P, In Zucker Diabetic Fatty Rats, Subclinical Diabetic Neuropathy Increases In Vivo Lidocaine Block Duration But Not In Vitro Neurotoxicity. REGION ANESTH PAIN M 2012;37 (6):601-606 [PubMed]
  • Lirk P, Haller I, Wong CA, Management of spinal anaesthesia-induced hypotension for caesarean delivery: a European survey. EUR J ANAESTH 2012;29 (9):452-453 [PubMed]
  • Stevens MF. Mechanisms of neuro- and cytotoxicity of local anesthetics and their adjuvants. s.l.: s.n.; 2012. 169p. [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Hollmann MW; copromotor(s): Lirk PB)

2011

  • Lirk P, Birmingham B, Hogan Q, Regional anesthesia in patients with preexisting neuropathy. INT ANESTHESIOL CLIN 2011;49 (4):144-165 [PubMed]

2010

  • Lirk P, Kleber N, Mitterschiffthaler G, Keller C, Benzer A, Putz G, Pulmonary effects of bupivacaine, ropivacaine, and levobupivacaine in parturients undergoing spinal anaesthesia for elective caesarean delivery: a randomised controlled study. INT J OBSTET ANESTH 2010;19 (3):287-292 [PubMed]
  • Ong CKS, Seymour RA, Lirk P, Merry AF, Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain. ANESTH ANALG 2010;110 (4):1170-1179 [PubMed]

2008

  • Hogan Q, Lirk P, Poroli M, Rigaud M, Fuchs A, Fillip P, Ljubkovic M, Gemes G, Sapunar D, Restoration of calcium influx corrects membrane hyperexcitability in injured rat dorsal root ganglion neurons. ANESTH ANALG 2008;107 (3):1045-1051 [PubMed]
  • Kirchmair L, Lirk P, Colvin J, Mitterschiffthaler G, Moriggl B, Lumbar plexus and psoas major muscle: not always as expected. REGION ANESTH PAIN M 2008;33 (2):109-114 [PubMed]
  • Lirk P, Haller I, Colvin HP, Lang L, Tomaselli B, Klimaschewski L, Gerner P, In vitro, inhibition of mitogen-activated protein kinase pathways protects against bupivacaine- and ropivacaine-induced neurotoxicity. ANESTH ANALG 2008;106 (5):1456-64, table of contents [PubMed]
  • Lirk P, Poroli M, Rigaud M, Fuchs A, Fillip P, Huang CY, Ljubkovic M, Sapunar D, Hogan Q, Modulators of calcium influx regulate membrane excitability in rat dorsal root ganglion neurons. ANESTH ANALG 2008;107 (2):673-685 [PubMed]
  • Rigaud M, Filip P, Lirk P, Fuchs A, Gemes G, Hogan Q, Guidance of block needle insertion by electrical nerve stimulation: a pilot study of the resulting distribution of injected solution in dogs. ANESTHESIOLOGY 2008;109 (3):473-478 [PubMed]
  • Schmutzhard J, Rieder J, Deibl M, Schwentner IM, Schmid S, Lirk P , Abraham I, Gunkel AR, Pilot study: volatile organic compounds as a diagnostic marker for head and neck tumors. HEAD NECK-J SCI SPEC 2008;30 (6):743-749 [PubMed]

2007

  • Fridrich P, Colvin HP, Zizza A, Wasan AD, Lukanich J, Lirk P, Saria A, Zernig G, Hamp T, Gerner P, Phase 1A safety assessment of intravenous amitriptyline. J PAIN 2007;8 (7):549-555 [PubMed]
  • Haller I, Lirk P, Keller C, Wang GK, Gerner P, Klimaschewski L, Differential neurotoxicity of tricyclic antidepressants and novel derivatives in vitro in a dorsal root ganglion cell culture model. EUR J ANAESTH 2007;24 (8):702-708 [PubMed]
  • Hung YC, Chen CY, Lirk P, Wang CF, Cheng JK, Chen CC, Wang GK, Gerner P, Magnesium sulfate diminishes the effects of amide local anesthetics in rat sciatic-nerve block. REGION ANESTH PAIN M 2007;32 (4):288-295 [PubMed]
  • Lirk P, Haller I, Colvin HP, Frauscher S, Kirchmair L, Gerner P, Klimaschewski L, In vitro, lidocaine-induced axonal injury is prevented by peripheral inhibition of the p38 mitogen-activated protein kinase, but not by inhibiting caspase activity. ANESTH ANALG 2007;105 (6):1657-64, table of contents [PubMed]
  • Ong CKS, Lirk P, Tan CH, Seymour RA, An evidence-based update on nonsteroidal anti-inflammatory drugs. CLIN MED RES 2007;5 (1):19-34 [PubMed]

2006

  • Almeling M, Schega L, Witten F, Lirk P, Wulf K, Validity of cycle test in air compared to underwater cycling. UNDERSEA HYPERBAR M 2006;33 (1):45-53 [PubMed]
  • Haller I, Hausott B, Tomaselli B, Keller C, Klimaschewski L, Gerner P, Lirk P, Neurotoxicity of lidocaine involves specific activation of the p38 mitogen-activated protein kinase, but not extracellular signal-regulated or c-jun N-terminal kinases, and is mediated by arachidonic acid metabolites. ANESTHESIOLOGY 2006;105 (5):1024-1033 [PubMed]
  • Lirk P, Haller I, Hausott B, Ingorokva S, Deibl M, Gerner P, Klimaschewski L, The neurotoxic effects of amitriptyline are mediated by apoptosis and are effectively blocked by inhibition of caspase activity. ANESTH ANALG 2006;102 (6):1728-1733 [PubMed]
  • Lirk P, Haller I, Myers RR, Klimaschewski L, Kau YC, Hung YC, Gerner P, Mitigation of direct neurotoxic effects of lidocaine and amitriptyline by inhibition of p38 mitogen-activated protein kinase in vitro and in vivo. ANESTHESIOLOGY 2006;104 (6):1266-1273 [PubMed]

2005

  • Friesenecker BE, Peer R, Rieder J, Lirk P, Knotzer H, Hasibeder WR, Mayr AJ, Dünser MW, Craniotomy during ECMO in a severely traumatized patient. ACTA NEUROCHIR 2005;147 (9):993-6; discussion 996 [PubMed]
  • Fuchs A, Lirk P, Stucky C, Abram SE, Hogan QH, Painful nerve injury decreases resting cytosolic calcium concentrations in sensory neurons of rats. ANESTHESIOLOGY 2005;102 (6):1217-1225 [PubMed]
  • Lechner M, Karlseder A, Niederseer D, Lirk P, Neher A, Rieder J, Tilg H, H. pylori infection increases levels of exhaled nitrate. HELICOBACTER 2005;10 (5):385-390 [PubMed]
  • Lechner M, Lirk P, Rieder J, Inducible nitric oxide synthase (iNOS) in tumor biology: the two sides of the same coin. SEMIN CANCER BIOL 2005;15 (4):277-289 [PubMed]
  • Lirk P, Colvin JM, Biebl M, Mitterschiffthaler G, Moser PL, Lorenz IH, Kolbitsch C, Bewertung eines Anatomieworkshops für die Regionalanästhesieausbildung. ANAESTHESIST 2005;54 (4):327-332 [PubMed]
  • Lirk P, Colvin J, Steger B, Colvin HP, Keller C, Rieder J, Kolbitsch C, Moriggl B, Incidence of lower thoracic ligamentum flavum midline gaps. BRIT J ANAESTH 2005;94 (6):852-855 [PubMed]
  • Moser B, Bodrogi F, Eibl G, Lechner M, Rieder J, Lirk P, Mass spectrometric profile of exhaled breath--field study by PTR-MS. RESP PHYSIOL NEUROBI 2005;145 (2-3):295-300 [PubMed]
  • Ong CKS, Lirk P, Seymour RA, Jenkins BJ, The efficacy of preemptive analgesia for acute postoperative pain management: a meta-analysis. ANESTH ANALG 2005;100 (3):757-73, table of contents [PubMed]
  • Ong CKS, Lirk P, Tan JMH, Sow BWY, The analgesic efficacy of intravenous versus oral tramadol for preventing postoperative pain after third molar surgery. J ORAL MAXIL SURG 2005;63 (8):1162-1168 [PubMed]
  • Ong KS, Seymour RA, Yeo JF, Ho KH, Lirk P, The efficacy of preoperative versus postoperative rofecoxib for preventing acute postoperative dental pain: a prospective randomized crossover study using bilateral symmetrical oral surgery. CLIN J PAIN 2005;21 (6):536-542 [PubMed]
  • Pinggera GM, Lirk P , Bodogri F, Herwig R, Steckel-Berger G, Bartsch G, Rieder J, Urinary acetonitrile concentrations correlate with recent smoking behaviour. BJU INT 2005;95 (3):306-309 [PubMed]
  • Rieder J, Lirk P, Bodrogi F, Sawires M, Gruber G, Hoffmann G, Cisatracurium, but not mivacurium, induces apoptosis in human umbilical vein endothelial cells in vitro. EUR J ANAESTH 2005;22 (1):16-19 [PubMed]
  • Sapunar D, Ljubkovic M, Lirk P, McCallum JB, Hogan QH, Distinct membrane effects of spinal nerve ligation on injured and adjacent dorsal root ganglion neurons in rats. ANESTHESIOLOGY 2005;103 (2):360-376 [PubMed]
  • von Goedecke A, Keller C, Moriggl B, Wenzel V, Bale R, Deibl M, Moser P, Lirk P, An anatomic landmark to simplify subclavian vein cannulation: the "deltoid tuberosity". ANESTH ANALG 2005;100 (3):623-8, table of contents [PubMed]

2004

  • Dünser MW, Ohlbauer M, Rieder J, Zimmermann I, Ruatti H, Schwabegger AH, Bodrogi F, Huemer GM, Friesenecker BE, Mayr AJ, Lirk P, Critical care management of major hydrofluoric acid burns: a case report, review of the literature, and recommendations for therapy. BURNS 2004;30 (4):391-398 [PubMed]
  • Hinteregger M, Zschiegner F, Lirk P, Ladner E, Goeschl A, Gaber O, Moser P, Lorenz I, Kolbitsch C, A new guidance device facilitates percutaneous puncture of the foramen ovale in human cadavers. CAN J ANAESTH 2004;51 (10):990-992 [PubMed]
  • Keller C, Brimacombe J, Bittersohl J, Lirk P, von Goedecke A, Aspiration and the laryngeal mask airway: three cases and a review of the literature. BRIT J ANAESTH 2004;93 (4):579-582 [PubMed]
  • Keller C, Brimacombe J, Lirk P, Pühringer F, Failed obstetric tracheal intubation and postoperative respiratory support with the ProSeal laryngeal mask airway. ANESTH ANALG 2004;98 (5):1467-70, table of contents [PubMed]
  • Keller C, Brimacombe J, Moriggl B, Lirk P, von Goedecke A, In cadavers, directly measured mucosal pressures are similar for the Unique and the Soft Seal laryngeal mask airway devices. CAN J ANAESTH 2004;51 (8):834-837 [PubMed]
  • Keller C, Brimacombe J, von Goedecke A, Lirk P, Airway protection with the ProSeal laryngeal mask airway in a child. PEDIATR ANESTH 2004;14 (12):1021-1022 [PubMed]
  • Lirk P, Bodrogi F, Deibl M, Kähler CM, Colvin J, Moser B, Pinggera G, Raifer H, Rieder J, Schobersberger W, Quantification of recent smoking behaviour using proton transfer reaction-mass spectrometry (PTR-MS). WIEN KLIN WOCHENSCHR 2004;116 (1-2):21-25 [PubMed]
  • Lirk P, Keller C, Colvin J, Colvin H, Rieder J, Maurer H, Moriggl B, Unintentional arterial puncture during cephalic vein cannulation: case report and anatomical study. BRIT J ANAESTH 2004;92 (5):740-742 [PubMed]
  • Lirk P, Keller C, Colvin J, Rieder J, Wulf K, Anaesthetic management of the Prader-Willi syndrome. EUR J ANAESTH 2004;21 (10):831-833 [PubMed]
  • Lirk P, Longato S, Rieder J, Klimaschewski L, Cisatracurium, but not mivacurium, inhibits survival and axonal growth of neonatal and adult rat peripheral neurons in vitro. NEUROSCI LETT 2004;365 (2):153-155 [PubMed]
  • Lirk P, Messner H, Deibl M, Mitterschiffthaler G, Colvin J, Steger B, Rieder J, Keller C, Accuracy in estimating the correct intervertebral space level during lumbar, thoracic and cervical epidural anaesthesia. ACTA ANAESTH SCAND 2004;48 (3):347-349 [PubMed]
  • Lirk P, Moriggl B, Colvin J, Keller C, Kirchmair L, Rieder J, Kolbitsch C, The incidence of lumbar ligamentum flavum midline gaps. ANESTH ANALG 2004;98 (4):1178-80, table of contents [PubMed]
  • Moser B, Lirk P, Lechner M, Gottardis M, General anaesthesia in a patient with motor neuron disease. EUR J ANAESTH 2004;21 (11):921-923 [PubMed]
  • Smolle M, Keller C, Pinggera G, Deibl M, Rieder J, Lirk P, Clear hydro-gel, compared to ointment, provides improved eye comfort after brief surgery. CAN J ANAESTH 2004;51 (2):126-129 [PubMed]

2003

  • Lirk P, Bodrogi F, Raifer H, Greiner K, Ulmer H, Rieder J, Elective haemodialysis increases exhaled isoprene. NEPHROL DIAL TRANSPL 2003;18 (5):937-941 [PubMed]
  • Lirk P, Kolbitsch C, Putz G, Colvin J, Colvin HP, Lorenz I, Keller C, Kirchmair L, Rieder J, Moriggl B, Cervical and high thoracic ligamentum flavum frequently fails to fuse in the midline. ANESTHESIOLOGY 2003;99 (6):1387-1390 [PubMed]
  • Lirk P, Rieder J, Schuerholz A, Keller C, Anaesthetic implications of Robinow syndrome. PEDIATR ANESTH 2003;13 (8):725-727 [PubMed]
  • Lorenz IH, Schubert HM, Lirk P, Moser PL, Hohlrieder M, Schlimp C, Hackl JM, Kolbitsch C, Evaluierung eines etablierten Universitätslehrganges für Krankenhausmanagement durch telefonische Befragung ehemaliger Teilnehmer. ANASTH INTENSIV NOTF 2003;38 (5):349-358 [PubMed]
  • Rieder J, Gruber G, Bodrogi F, Lirk P, Hoffmann G, Anaphylactoid reaction to cisatracurium may be explained by atracurium metabolites. ANESTH ANALG 2003;96 (1):301; author reply 301 [PubMed]
  • Rieder J, Keller C, Hoffmann G, Lirk P, Moscow theatre siege and anaesthetic drugs. LANCET 2003;361 (9363):1131 [PubMed]
  • Rieder J, Lirk P, Hoffmann G, Neopterin as a potential modulator of tumor cell growth and proliferation. MED HYPOTHESES 2003;60 (4):531-534 [PubMed]
  • Summer G, Lirk P, Hoerauf K, Riccabona U, Bodrogi F, Raifer H, Deibl M, Rieder J, Schobersberger W, Sevoflurane in exhaled air of operating room personnel. ANESTH ANALG 2003;97 (4):1070-3, table of contents [PubMed]

2002

  • Gruber G, Lirk P, Amann A, Keller C, Schobersberger W, Hoffmann G, Fuchs D, Rieder J, Neopterin as a marker of immunostimulation: an investigation in anaesthetic workplaces. ANAESTHESIA 2002;57 (8):747-750 [PubMed]
  • Lirk P, Hoffmann G, Rieder J, Inducible nitric oxide synthase--time for reappraisal. CURR DRUG TARGETS INFLAMM ALLERGY 2002;1 (1):89-108 [PubMed]
  • Rieder J, Keller C, Brimacombe J, Gruber G, Lirk P, Summer G, Amann A, Monitoring pollution by proton-transfer-reaction mass spectrometry during paediatric anaesthesia with positive pressure ventilation via the laryngeal mask airway or uncuffed tracheal tube. ANAESTHESIA 2002;57 (7):663-666 [PubMed]
  • Rieder J, Lirk P, Neonatal atracurium toxicity may be explained by atracurium moieties. PEDIATR ANESTH 2002;12 (7):656-657 [PubMed]

2001

  • Rieder J, Lirk P, Ebenbichler C, Gruber G, Prazeller P, Lindinger W, Amann A, Analysis of volatile organic compounds: possible applications in metabolic disorders and cancer screening. WIEN KLIN WOCHENSCHR 2001;113 (5-6):181-185 [PubMed]
  • Rieder J, Lirk P, Summer G, Gunkel A, Riccabona U, Innerhofer P, Amann A, Exposure to sevoflurane in otorhinolaryngologic operations. CAN J ANAESTH 2001;48 (9):934 [PubMed]
  • Rieder J, Prazeller P, Boehler M, Lirk P, Lindinger W, Amann A, Online monitoring of air quality at the postanesthetic care unit by proton-transfer-reaction mass spectrometry. ANESTH ANALG 2001;92 (2):389-392 [PubMed]