Dr. R. Nieuwland publications

foto

Publications Dr. R. Nieuwland

Position
Scientific staff member (UD)
Main activities
Research, Teaching
Specialisation
Biologist
Focus of research

Detection and function of extracellular vesicles (microparticles, exosomes) and platelets in health and disease.

2019

  • Thery C, Witwer KW, Aikawa E, Jose Alcaraz M, Anderson JD, Andriantsitohaina R, Antoniou A, Arab T, Archer F, Atkin-Smith GK, Ayre DC, Bach JM, Bachurski D, Baharvand H, Balaj L, Baldacchino S, Bauer NN, Baxter AA, Bebawy M, Beckham C, Zavec AB, Benmoussa A, Berardi AC, Bergese P, Bielska E, Blenkiron C, Bobis-Wozowicz S, Boilard E, Boireau W, Bongiovanni A, Borras FE, Bosch S, Boulanger CM, Breakefield X, Breglio AM, Brennan MA, Brigstock DR, Brisson A, Broekman MLD, Bromberg JF, Bryl-Gorecka P, Buch S, Buck AH, Burger D, Busatto S, Buschmann D, Bussolati B, Buzas EI, Byrd JB, Camussi G, Carter DRF, Caruso S, Chamley LW, Chang YT, Chaudhuri AD, Chen C, Chen S, Cheng L, Chin AR, Clayton A, Clerici SP, Cocks A, Cocucci E, Coffey RJ, Cordeiro-da-Silva A, Couch Y, Coumans FAW, Coyle B, Crescitelli R, Criado MF, D'Souza-Schorey C, Das S, de Candia P, de Santana EF, de Wever O, del Portillo HA, Demaret T, Deville S, Devitt A, Dhondt B, Di Vizio D, Dieterich LC, Dolo V, Dominguez Rubio AP, Dominici M, Dourado MR, Driedonks TAP, Duarte FV, Duncan HM, Eichenberger RM, Ekstrom K, Andaloussi SEL, Elie-Caille C, Erdbrugger U, Falcon-Perez JM, Fatima F, Fish JE, Flores-Bellver M, Forsonits A, Frelet-Barrand A, Fricke F, Fuhrmann G, Gabrielsson S, Gamez-Valero A, Gardiner C, Gaertner K, Gaudin R, Gho YS, Giebel B, Gilbert C, Gimona M, Giusti I, Goberdhan DCI, Goergens A, Gorski SM, Greening DW, Gross JC, Gualerzi A, Gupta GN, Gustafson D, Handberg A, Haraszti RA, Harrison P, Hegyesi H, Hendrix A, Hill AF, Hochberg FH, Hoffmann KF, Holder B, Holthofer H, Hosseinkhani B, Hu G, Huang Y, Huber V, Hunt S, Ibrahim AGE, Ikezu T, Inal JM, Isin M, Ivanova A, Jackson HK, Jacobsen S, Jay SM, Jayachandran M, Jenster G, Jiang L, Johnson SM, Jones JC, Jong A, Jovanovic-Talisman T, Jung S, Kalluri R, Kano SI, Kaur S, Kawamura Y, Keller ET, Khamari D, Khomyakova E, Khvorova A, Kierulf P, Kim KP, Kislinger T, Klingeborn M, Klinke DJ II, Kornek M, Kosanovic MM, Kovacs AF, Kraemer-Albers EM, Krasemann S, Krause M, Kurochkin IV, Kusuma GD, Kuypers S, Laitinen S, Langevin SM, Languino LR, Lannigan J, Lasser C, Laurent LC, Lavieu G, Lazaro-Ibanez E, Le Lay S, Lee MS, Lee YXF, Lemos DS, Lenassi M, Leszczynska A, Li ITS, Liao K, Libregts SF, Ligeti E, Lim R, Lim SK, Line A, Linnemannstoens K, Llorente A, Lombard CA, Lorenowicz MJ, Lorincz AM, Lotvall J, Lovett J, Lowry MC, Loyer X, Lu Q, Lukomska B, Lunavat TR, Maas SLN, Malhi H, Marcilla A, Mariani J, Mariscal J, Martens-Uzunova ES, Martin-Jaular L, Martinez MC, Martins VR, Mathieu M, Mathivanan S, Maugeri M, McGinnis LK, McVey MJ, Meckes DG Jr, Meehan KL, Mertens I, Minciacchi VR, Moller A, Jorgensen MM, Morales-Kastresana A, Morhayim J, Mullier F, Muraca M, Musante L, Mussack V, Muth DC, Myburgh KH, Najrana T, Nawaz M, Nazarenko I, Nejsum P, Neri C, Neri T, Nieuwland R, Nimrichter L, Nolan JP, Hoen ENMNT, Hooten NN, O'Driscoll L, O'Grady T, O'Loghlen A, Ochiya T, Olivier M, Ortiz A, Ortiz LA, Osteikoetxea X, Ostegaard O, Ostrowski M, Park J, Pegtel DM, Peinado H, Perut F, Pfaffl MW, Phinney DG, Pieters BCH, Pink RC, Pisetsky DS, von Strandmann EP, Polakovicova I, Poon IKH, Powell BH, Prada I, Pulliam L, Quesenberry P, Radeghieri A, Raffai RL, Raimondo S, Rak J, Ramirez MI, Raposo G, Rayyan MS, Regev-Rudzki N, Ricklefs FL, Robbins PD, Roberts DD, Rodrigues SC, Rohde E, Rome S, Rouschop KMA, Rughetti A, Russell AE, Saa P, Sahoo S, Salas-Huenuleo E, Sanchez C, Saugstad JA, Saul MJ, Schiffelers RM, Schneider R, Schoyen TH, Scott A, Shahaj E, Sharma S, Shatnyeva O, Shekari F, Shelke GV, Shetty AK, Shiba K, Siljander PRM, Silva AM, Skowronek A, Snyder OL II, Soares RP, Sodar BW, Soekmadji C, Sotillo J, Stahl PD, Stoorvogel W, Stott SL, Strasser EF, Swift S, Tahara H, Tewari M, Timms K, Tiwari S, Tixeira R, Tkach M, Toh WS, Tomasini R, Torrecilhas AC, Pablo Tosar J, Toxavidis V, Urbanelli L, Vader P, van Balkom BWM, van der Grein SG, van Deun J, van Herwijnen MJC, van Keuren-Jensen K, van Niel G, van Royen ME, van Wijnen AJ, Helena Vasconcelos M, Vechetti IJ Jr, Veit TD, Vella LJ, Velot E, Verweij FJ, Vestad B, Vinas JL, Visnovitz T, Vukman KV, Wahlgren J, Watson DC, Wauben MHM, Weaver A, Webber JP, Weber V, Wehman AM, Weiss DJ, Welsh JA, Wendt S, Wheelock AM, Wiener Z, Witte L, Wolfram J, Xagorari A, Xander P, Xu J, Yan X, Yanez-Mo M, Yin H, Yuana Y, Zappulli V, Zarubova J, Zekas V, Zhang JY, Zhao Z, Zheng L, Zheutlin AR, Zickler AM, Zimmermann P, Zivkovic AM, Zocco D, Zuba-Surma EK, Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. J EXTRACELL VESICLES 2019;ahead of print

2018

  • Clayton A, Buschmann D, Byrd JB, Carter DRF, Cheng L, Compton C, Daaboul G, Devitt A, Manuel Falcon-Perez J, Gardiner C, Gustafson D, Harrison P, Helmbrecht C, Hendrix A, Hill A, Hoffman A, Jones JC, Kalluri R, Kang JY, Kirchner B, Lasser C, Lawson C, Lenassi M, Levin C, Llorente A, Martens-Uzunova ES, Moeller A, Musante L, Ochiya T, Pink RC, Tahara H, Wauben MHM, Webber JP, Welsh JA, Witwer KW, Yin H, Nieuwland R, Summary of the ISEV workshop on extracellular vesicles as disease biomarkers, held in Birmingham, UK, during December 2017. J EXTRACELL VESICLES 2018;7 (1):1473707
  • de Rond L, Coumans FAW, Nieuwland R, van Leeuwen TG, van der Pol E, Deriving Extracellular Vesicle Size From Scatter Intensities Measured by Flow Cytometry. CURR PROTOC CYTOM 2018;86 (1):e43 [PubMed]
  • de Rond L, van der Pol E, Hau CM, Varga Z, Sturk A, van Leeuwen TG, Nieuwland R, Coumans FAW, Comparison of Generic Fluorescent Markers for Detection of Extracellular Vesicles by Flow Cytometry. CLIN CHEM 2018;64 (4):680-689 [PubMed]
  • Gasecka A, Nieuwland R, Budnik M, Dignat-George F, Eyileten C, Harrison P, Huczek Z, Kapłon-Cieślicka A, Lacroix R, Opolski G, Pluta K, van der Pol E, Postuła M, Leroyer A, Siljander P, Sturk A, Filipiak KJ, Randomized controlled trial protocol to investigate the antiplatelet therapy effect on extracellular vesicles (AFFECT EV) in acute myocardial infarction. PLATELETS 2018;ahead of print [PubMed]
  • Gasecka A, Nieuwland R, van der Pol E, Hajji N, Ćwiek A, Pluta K, Konwerski M, Filipiak KJ, P2Y12 antagonist ticagrelor inhibits the release of procoagulant extracellular vesicles from activated platelets: Preliminary results. CARDIOL J 2018;ahead of print [PubMed]
  • Gąsecka A, van der Pol E, Nieuwland R, Stępień E, Extracellular vesicles in post-infarct ventricular remodelling. KARDIOL POL 2018;76 (1):69-76 [PubMed]
  • Jansen MPB, Pulskens WPC, Uil M, Claessen N, Nieuwenhuizen G, Standaar D, Hau CM, Nieuwland R, Florquin S, Bemelman FJ, Leemans JC, Roelofs JJTH, Urinary mitochondrial deoxyribonucleic acid associates with delayed graft function following renal transplantation. NEPHROL DIAL TRANSPL 2018;ahead of print [PubMed]
  • Karimi N, Cvjetkovic A, Jang SC, Crescitelli R, Hosseinpour Feizi MA, Nieuwland R, Lötvall J, Lässer C, Detailed analysis of the plasma extracellular vesicle proteome after separation from lipoproteins. CELL MOL LIFE SCI 2018;75 (15):2873-2886 [PubMed]
  • Kastelein AW, Vos LMC, de Jong KH, van Baal JOAM, Nieuwland R, van Noorden CJF, Roovers JPWR, Lok CAR, Embryology, Anatomy, Physiology and Pathophysiology of the Peritoneum and the Peritoneal Vasculature. SEMIN CELL DEV BIOL 2018;ahead of print [PubMed]
  • Nieuwland R, Falcon-Perez JM, Soekmadji C, Boilard E, Carter D, Buzas EI, Essentials of extracellular vesicles: posters on basic and clinical aspects of extracellular vesicles. J EXTRACELL VESICLES 2018;7 (1):1548234 [PubMed]
  • Peters AL, Vlaar APJ, van Bruggen R, de Korte D, Meijers JCM, Nieuwland R, Juffermans NP, Transfusion of autologous extracellular vesicles from stored red blood cells does not affect coagulation in a model of human endotoxemia. TRANSFUSION 2018;58 (6):1486-1493 [PubMed]
  • Rank A, Nieuwland R, Köhler A, Franz C, Waidhauser J, Toth B, Human bone marrow contains high levels of extracellular vesicles with a tissue-specific subtype distribution. PLOS ONE 2018;13 (12):e0207950 [PubMed]
  • Rikkert LG, van der Pol E, van Leeuwen TG, Nieuwland R, Coumans FAW, Centrifugation affects the purity of liquid biopsy-based tumor biomarkers. CYTOM PART A 2018;93 (12):1207-1212 [PubMed]
  • Smit KF, Konkel M, Kerindongo R, Landau MA, Zuurbier CJ, Hollman MW, Preckel B, Nieuwland R, Albrecht M, Weber NC, Helium alters the cytoskeleton and decreases permeability in endothelial cells cultured in vitro through a pathway involving Caveolin-1. SCI REP-UK 2018;8 (4768):--- [PubMed]
  • Thery C, Witwer KW, Aikawa E, Jose Alcaraz M, Anderson JD, Andriantsitohaina R, Antoniou A, Arab T, Archer F, Atkin-Smith GK, Ayre DC, Bach JM, Bachurski D, Baharvand H, Balaj L, Baldacchino S, Bauer NN, Baxter AA, Bebawy M, Beckham C, Zavec AB, Benmoussa A, Berardi AC, Bergese P, Bielska E, Blenkiron C, Bobis-Wozowicz S, Boilard E, Boireau W, Bongiovanni A, Borras FE, Bosch S, Boulanger CM, Breakefield X, Breglio AM, Brennan MA, Brigstock DR, Brisson A, Broekman MLD, Bromberg JF, Bryl-Gorecka P, Buch S, Buck AH, Burger D, Busatto S, Buschmann D, Bussolati B, Buzas EI, Byrd JB, Camussi G, Carter DRF, Caruso S, Chamley LW, Chang YT, Chen C, Chen S, Cheng L, Chin AR, Clayton A, Clerici SP, Cocks A, Cocucci E, Coffey RJ, Cordeiro-da-Silva A, Couch Y, Coumans FAW, Coyle B, Crescitelli R, Criado MF, D'Souza-Schorey C, Das S, Chaudhuri AD, de Candia P, de Santana EF, de Wever O, del Portillo HA, Demaret T, Deville S, Devitt A, Dhondt B, Di Vizio D, Dieterich LC, Dolo V, Dominguez Rubio AP, Dominici M, Dourado MR, Driedonks TAP, Duarte FV, Duncan HM, Eichenberger RM, Ekstrom K, Andaloussi SEL, Elie-Caille C, Erdbrugger U, Falcon-Perez JM, Fatima F, Fish JE, Flores-Bellver M, Forsonits A, Frelet-Barrand A, Fricke F, Fuhrmann G, Gabrielsson S, Gamez-Valero A, Gardiner C, Gaertner K, Gaudin R, Gho YS, Giebel B, Gilbert C, Gimona M, Giusti I, Goberdhan DCI, Goergens A, Gorski SM, Greening DW, Gross JC, Gualerzi A, Gupta GN, Gustafson D, Handberg A, Haraszti RA, Harrison P, Hegyesi H, Hendrix A, Hill AF, Hochberg FH, Hoffmann KF, Holder B, Holthofer H, Hosseinkhani B, Hu G, Huang Y, Huber V, Hunt S, Ibrahim AGE, Ikezu T, Inal JM, Isin M, Ivanova A, Jackson HK, Jacobsen S, Jay SM, Jayachandran M, Jenster G, Jiang L, Johnson SM, Jones JC, Jong A, Jovanovic-Talisman T, Jung S, Kalluri R, Kano SI, Kaur S, Kawamura Y, Keller ET, Khamari D, Khomyakova E, Khvorova A, Kierulf P, Kim KP, Kislinger T, Klingeborn M, Klinke DJ II, Kornek M, Kosanovic MM, Kovacs AF, Kraemer-Albers EM, Krasemann S, Krause M, Kurochkin IV, Kusuma GD, Kuypers S, Laitinen S, Langevin SM, Languino LR, Lannigan J, Lasser C, Laurent LC, Lavieu G, Lazaro-Ibanez E, Le Lay S, Lee MS, Lee YXF, Lemos DS, Lenassi M, Leszczynska A, Li ITS, Liao K, Libregts SF, Ligeti E, Lim R, Lim SK, Line A, Linnemannstoens K, Llorente A, Lombard CA, Lorenowicz MJ, Lorincz AM, Lotvall J, Lovett J, Lowry MC, Loyer X, Lu Q, Lukomska B, Lunavat TR, Maas SLN, Malhi H, Marcilla A, Mariani J, Mariscal J, Martens-Uzunova ES, Martin-Jaular L, Martinez MC, Martins VR, Mathieu M, Mathivanan S, Maugeri M, McGinnis LK, McVey MJ, Meckes DG Jr, Meehan KL, Mertens I, Minciacchi VR, Moller A, Jorgensen MM, Morales-Kastresana A, Morhayim J, Mullier F, Muraca M, Musante L, Mussack V, Muth DC, Myburgh KH, Najrana T, Nawaz M, Nazarenko I, Nejsum P, Neri C, Neri T, Nieuwland R, Nimrichter L, Nolan JP, Nolte-'t Hoen ENM, Hooten NN, O'Driscoll L, O'Grady T, O'Loghlen A, Ochiya T, Olivier M, Ortiz A, Ortiz LA, Osteikoetxea X, Ostegaard O, Ostrowski M, Park J, Pegtel DM, Peinado H, Perut F, Pfaffl MW, Phinney DG, Pieters BCH, Pink RC, Pisetsky DS, von Strandmann EP, Polakovicova I, Poon IKH, Powell BH, Prada I, Pulliam L, Quesenberry P, Radeghieri A, Raffai RL, Raimondo S, Rak J, Ramirez MI, Raposo G, Rayyan MS, Regev-Rudzki N, Ricklefs FL, Robbins PD, Roberts DD, Rodrigues SC, Rohde E, Rome S, Rouschop KMA, Rughetti A, Russell AE, Saa P, Sahoo S, Salas-Huenuleo E, Sanchez C, Saugstad JA, Saul MJ, Schiffelers RM, Schneider R, Schoyen TH, Scott A, Shahaj E, Sharma S, Shatnyeva O, Shekari F, Shelke GV, Shetty AK, Shiba K, Siljander PRM, Silva AM, Skowronek A, Snyder OL II, Soares RP, Sodar BW, Soekmadji C, Sotillo J, Stahl PD, Stoorvogel W, Stott SL, Strasser EF, Swift S, Tahara H, Tewari M, Timms K, Tiwari S, Tixeira R, Tkach M, Toh WS, Tomasini R, Torrecilhas AC, Pablo Tosar J, Toxavidis V, Urbanelli L, Vader P, van Balkom BWM, van der Grein SG, van Deun J, van Herwijnen MJC, van Keuren-Jensen K, van Niel G, van Royen ME, van Wijnen AJ, Helena Vasconcelos M, Vechetti IJ Jr, Veit TD, Vella LJ, Velot E, Verweij FJ, Vestad B, Vinas JL, Visnovitz T, Vukman KV, Wahlgren J, Watson DC, Wauben MHM, Weaver A, Webber JP, Weber V, Wehman AM, Weiss DJ, Welsh JA, Wendt S, Wheelock AM, Wiener Z, Witte L, Wolfram J, Xagorari A, Xander P, Xu J, Yan X, Yanez-Mo M, Yin H, Yuana Y, Zappulli V, Zarubova J, Zekas V, Zhang JY, Zhao Z, Zheng L, Zheutlin AR, Zickler AM, Zimmermann P, Zivkovic AM, Zocco D, Zuba-Surma EK, Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. J EXTRACELL VESICLES 2018;7 (1):1535750
  • van Baal JOAM, van Noorden CJF, Nieuwland R, van de Vijver KK, Sturk A, van Driel WJ, Kenter GG, Lok CAR, Development of Peritoneal Carcinomatosis in Epithelial Ovarian Cancer: A Review. J HISTOCHEM CYTOCHEM 2018;66 (2):67-83 [PubMed]
  • van der Pol E, de Rond L, Coumans FAW, Gool EL, Böing AN, Sturk A, Nieuwland R, van Leeuwen TG, Absolute sizing and label-free identification of extracellular vesicles by flow cytometry. NANOMED-NANOTECHNOL 2018;14 (3):801-810 [PubMed]
  • van der Pol E, Sturk A, van Leeuwen T, Nieuwland R, Coumans F, Standardization of extracellular vesicle measurements by flow cytometry through vesicle diameter approximation. J THROMB HAEMOST 2018;16 (6):1236-1245 [PubMed]
  • van Es N, Hisada Y, Di Nisio M, Cesarman G, Kleinjan A, Mahé I, Otten HM, Kamphuisen PW, Berckmans RJ, Büller HR, Mackman N, Nieuwland R, Extracellular vesicles exposing tissue factor for the prediction of venous thromboembolism in patients with cancer: A prospective cohort study. THROMB RES 2018;166:54-59 [PubMed]
  • Varga Z, van der Pol E, Pálmai M, Garcia-Diez R, Gollwitzer C, Krumrey M, Fraikin JL, Gasecka A, Hajji N, van Leeuwen TG, Nieuwland R, Hollow organosilica beads as reference particles for optical detection of extracellular vesicles. J THROMB HAEMOST 2018;16 (8):1646-1655 [PubMed]
  • Yu Y , Böing AN, Hau CM, Hajji N, Ruf W, Sturk A, Nieuwland R, Tissue Factor Coagulant Activity is Regulated by the Plasma Membrane Microenvironment. THROMB HAEMOSTASIS 2018;118 (6):990-1000 [PubMed]
  • Yu Y, Gool E, Berckmans RJ, Coumans FAW, Barendrecht AD, Maas C, van der Wel NN, Altevogt P, Sturk A, Nieuwland R, Extracellular vesicles from human saliva promote hemostasis by delivering coagulant tissue factor to activated platelets. J THROMB HAEMOST 2018;16 (6):1153-1163 [PubMed]

2017

  • Aatonen M, Valkonen S, Böing A, Yuana Y, Nieuwland R, Siljander P, Isolation of Platelet-Derived Extracellular Vesicles. METHODS MOL BIOL 2017;1545 (-):177-188 [PubMed]
  • Cointe S, Judicone C, Robert S, Mooberry MJ, Poncelet P, Wauben M, Nieuwland R, Key NS, Dignat-George F, Lacroix R, Standardization of microparticle enumeration across different flow cytometry platforms: results of a multicenter collaborative workshop. J THROMB HAEMOST 2017;15 (1):187-193 [PubMed]
  • Coumans FAW, Brisson AR, Buzas EI, Dignat-George F, Drees EEE, El-Andaloussi S, Emanueli C, Gasecka A, Hendrix A, Hill AF, Lacroix R, Lee Y, van Leeuwen TG, Mackman N, Mäger I, Nolan JP, van der Pol E, Pegtel DM, Sahoo S, Siljander PRM, Sturk G, de Wever O, Nieuwland R, Methodological Guidelines to Study Extracellular Vesicles. CIRC RES 2017;120 (10):1632-1648 [PubMed]
  • Coumans FAW, Gool EL, Nieuwland R, Bulk immunoassays for analysis of extracellular vesicles. PLATELETS 2017;28 (3):242-248 [PubMed]
  • Gasecka A, Böing AN, Filipiak KJ, Nieuwland R, Platelet extracellular vesicles as biomarkers for arterial thrombosis. PLATELETS 2017;28 (3):228-234 [PubMed]
  • Gool EL, Stojanovic I, Schasfoort RBM, Sturk A, van Leeuwen TG, Nieuwland R, Terstappen LWMM, Coumans FAW, Surface Plasmon Resonance is an Analytically Sensitive Method for Antigen Profiling of Extracellular Vesicles. CLIN CHEM 2017;63 (10):1633-1641 [PubMed]
  • Hezel MEv, Nieuwland R, Bruggen Rv, Juffermans NP, The Ability of Extracellular Vesicles to Induce a Pro-Inflammatory Host Response. INT J MOL SCI 2017;18 (6):1285 [PubMed]
  • Karamat FA, Horjus DL, Haan YC, van der Woude L, Schaap MC, Oudman I, van Montfrans GA, Nieuwland R, Salomons GS, Clark JF, Brewster LM, The acute effect of beta-guanidinopropionic acid versus creatine or placebo in healthy men (ABC-Trial): A randomized controlled first-in-human trial. BRIT J CLIN PHARMACO 2017;83 (12):2626-2635 [PubMed]
  • Peters AL, Vervaart MAT, van Bruggen R, de Korte D, Nieuwland R, Kulik W, Vlaar APJ, Non-polar lipids accumulate during storage of transfusion products and do not contribute to the onset of transfusion-related acute lung injury. VOX SANG 2017;112 (1):25-32 [PubMed]
  • Ridger VC, Boulanger CM, Angelillo-Scherrer A, Badimon L, Blanc-Brude O, Bochaton-Piallat ML, Boilard E, Buzas EI, Caporali A, Dignat-George F, Evans PC, Lacroix R, Lutgens E, Ketelhuth DFJ, Nieuwland R, Toti F, Tunon J, Weber C, Hoefer IE, Microvesicles in vascular homeostasis and diseases. Position Paper of the European Society of Cardiology (ESC) Working Group on Atherosclerosis and Vascular Biology. THROMB HAEMOSTASIS 2017;117 (7):1296-1316 [PubMed]
  • Sebaihi N, de Boeck B, Yuana Y, Nieuwland R, Petry J, Dimensional characterization of extracellular vesicles using atomic force microscopy. MEAS SCI TECHNOL 2017;28 (3):034006
  • Valkonen S, van der Pol E, Böing A, Yuana Y, Yliperttula M, Nieuwland R, Laitinen S, Siljander PRM, Biological reference materials for extracellular vesicle studies. EUR J PHARM SCI 2017;98:4-16 [PubMed]
  • van Baal JOAM, van de Vijver KK, Nieuwland R, van Noorden CJF, van Driel WJ, Sturk A, Kenter GG, Rikkert LG, Lok CAR, The histophysiology and pathophysiology of the peritoneum. TISSUE CELL 2017;49 (1):95-105 [PubMed]
  • van Es N, Di Nisio M, Cesarman G, Kleinjan A, Otten HM, Mahé I, Wilts IT, Twint DC, Porreca E, Arrieta O, Stépanian A, Smit K, de Tursi M, Bleker SM, Bossuyt PM, Nieuwland R, Kamphuisen PW, Büller HR, Comparison of risk prediction scores for venous thromboembolism in cancer patients: a prospective cohort study. HAEMATOLOGICA 2017;102 (9):1494-1501 [PubMed]
  • Witwer KW, Soekmadji C, Hill AF, Wauben MH, Buzás EI, Di Vizio D, Falcon-Perez JM, Gardiner C, Hochberg F, Kurochkin IV, Lötvall J, Mathivanan S, Nieuwland R, Sahoo S, Tahara H, Torrecilhas AC, Weaver AM, Yin H, Zheng L, Gho YS, Quesenberry P, Théry C, Updating the MISEV minimal requirements for extracellular vesicle studies: building bridges to reproducibility. J EXTRACELL VESICLES 2017;6 (1):1396823 [PubMed]

2016

  • de Stoppelaar SF, Claushuis TAM, Schaap MCL, Hou B, van der Poll T, Nieuwland R, van 't Veer C, Toll-Like Receptor Signalling Is Not Involved in Platelet Response to Streptococcus pneumoniae In Vitro or In Vivo. PLOS ONE 2016;11 (6):e0156977 [PubMed]
  • Franz C, Böing AN, Montag M, Strowitzki T, Markert UR, Mastenbroek S, Nieuwland R, Toth B, Extracellular vesicles in human follicular fluid do not promote coagulation. REPROD BIOMED ONLINE 2016;33 (5):652-655 [PubMed]
  • Kok MGM, Mandolini C, Moerland PD, de Ronde MWJ, Sondermeijer BM, Halliani A, Nieuwland R, Cipollone F, Creemers EE, Meijers JCM, Pinto-Sietsma SJ, Low miR-19b-1-5p expression in isolated platelets after aspirin use is related to aspirin insensitivity. INT J CARDIOL 2016;203:262-263 [PubMed]
  • Nicolet A, Meli F, van der Pol E, Yuana Y, Gollwitzer C, Krumrey M, Cizmar P, Buhr E, Petry J, Sebaihi N, de Boeck B, Fokkema V, Bergmans R, Nieuwland R, Inter-laboratory comparison on the size and stability of monodisperse and bimodal synthetic reference particles for standardization of extracellular vesicle measurements. MEAS SCI TECHNOL 2016;27 (3):035701
  • Straat M, Boing AN, Tuip-de Boer A, Nieuwland R, Juffermans NP, Extracellular Vesicles from Red Blood Cell Products Induce a Strong Pro-Inflammatory Host Response, Dependent on Both Numbers and Storage Duration. TRANSFUS MED HEMOTH 2016;43 (4):302-305
  • Straat M, van Hezel ME, Böing A, Tuip-de Boer A, Weber N, Nieuwland R, van Bruggen R, Juffermans NP, Monocyte-mediated activation of endothelial cells occurs only after binding to extracellular vesicles from red blood cell products, a process mediated by β-integrin. TRANSFUSION 2016;56 (12):3012-3020 [PubMed]
  • van der Pol E, Böing AN, Gool EL, Nieuwland R, Recent developments in the nomenclature, presence, isolation, detection and clinical impact of extracellular vesicles. J THROMB HAEMOST 2016;14 (1):48-56 [PubMed]
  • van der Pol E, Mudde YD, Coumans FAW, van Leeuwen TG, Sturk A, Nieuwland R, Wound scabs protect regenerating tissue against harmful ultraviolet radiation. MED HYPOTHESES 2016;96:39-41 [PubMed]
  • van Eijndhoven MAJ, Zijlstra JM, Groenewegen NJ, Drees EEE, van Niele S, Baglio SR, Koppers-Lalic D, van der Voorn H, Libregts SFWM, Wauben MHM, de Menezes RX, van Weering JRT, Nieuwland R, Visser L, van den Berg A, de Jong D, Pegtel DM, Plasma vesicle miRNAs for therapy response monitoring in Hodgkin lymphoma patients. JCI INSIGHT 2016;1 (19):e89631 [PubMed]
  • Vogel R, Coumans FAW, Maltesen RG, Böing AN, Bonnington KE, Broekman ML, Broom MF, Buzás EI, Christiansen G, Hajji N, Kristensen SR, Kuehn MJ, Lund SM, Maas SLN, Nieuwland R, Osteikoetxea X, Schnoor R, Scicluna BJ, Shambrook M, de Vrij J, Mann SI, Hill AF, Pedersen S, A standardized method to determine the concentration of extracellular vesicles using tunable resistive pulse sensing. J EXTRACELL VESICLES 2016;5:31242 [PubMed]

2015

  • Ayers L, Nieuwland R, Kohler M, Kraenkel N, Ferry B, Leeson P, Dynamic microvesicle release and clearance within the cardiovascular system: triggers and mechanisms. CLIN SCI 2015;129 (11):915-931 [PubMed]
  • Balvers K, Curry N, Kleinveld DJB, Böing AN, Nieuwland R, Goslings JC, Juffermans NP, Endogenous microparticles drive the proinflammatory host immune response in severely injured trauma patients. SHOCK 2015;43 (4):317-321 [PubMed]
  • de Boer JD, Berger M, Majoor CJ , Kager LM, Meijers JCM, Terpstra S, Nieuwland R, Boing AN, Lutter R, Wouters D, van Mierlo GJ, Zeerleder SS, Bel EH, van't Veer C, de Vos AF, van der Zee JS, van der Poll T, Activated protein C inhibits neutrophil migration in allergic asthma: a randomised trial. EUR RESPIR J 2015;46 (6):1636-1644 [PubMed]
  • Gardiner C, Harrison P, Belting M, Böing A, Campello E, Carter BS, Collier ME, Coumans F, Ettelaie C, van Es N, Hochberg FH, Mackman N, Rennert RC, Thaler J, Rak J, Nieuwland R, Extracellular vesicles, tissue factor, cancer and thrombosis - discussion themes of the ISEV 2014 Educational Day. J EXTRACELL VESICLES 2015;4:UNSP 26901 [PubMed]
  • Kim DK, Lee J, Kim SR, Choi DS, Yoon YJ, Kim JH, Go G, Nhung D, Hong K, Jang SC, Kim SH, Park KS, Kim OY, Park HT, Seo JH, Aikawa E, Baj-Krzyworzeka M, van Balkom BWM, Belting M, Blanc L, Bond V, Bongiovanni A, Borràs FE, Buée L, Buzás EI, Cheng L, Clayton A, Cocucci E, Dela Cruz CS, Desiderio DM, Di Vizio D, Ekström K, Falcon-Perez JM, Gardiner C, Giebel B, Greening DW, Gross JC, Gupta D, Hendrix A, Hill AF, Hill MM, Nolte-'t Hoen E, Hwang DW, Inal J, Jagannadham MV, Jayachandran M, Jee YK, Jørgensen M, Kim KP, Kim YK, Kislinger T, Lässer C, Lee DS, Lee H, van Leeuwen J, Lener T, Liu ML, Lötvall J, Marcilla A, Mathivanan S, Möller A, Morhayim J, Mullier F, Nazarenko I, Nieuwland R, Nunes DN, Pang K, Park J, Patel T, Pocsfalvi G, del Portillo H, Putz U, Ramirez MI, Rodrigues ML, Roh TY, Royo F, Sahoo S, Schiffelers R, Sharma S, Siljander P, Simpson RJ, Soekmadji C, Stahl P, Stensballe A, Stępień E, Tahara H, Trummer A, Valadi H, Vella LJ, Wai SN, Witwer K, Yáñez-Mó M, Youn H, Zeidler R, Gho YS, EVpedia: a community web portal for extracellular vesicles research. BIOINFORMATICS 2015;31 (6):933-939 [PubMed]
  • Smit KF, Kerindongo RP, Böing A, Nieuwland R, Hollmann MW, Preckel B, Weber NC, Effects of helium on inflammatory and oxidative stress-induced endothelial cell damage. EXP CELL RES 2015;337 (1):37-43 [PubMed]
  • van der Meijden PEJ, Ozaki Y, Ruf W, de Laat B, Mutch N, Diamond S, Nieuwland R, Peters TC, Heestermans M, Kremers RMW, Moorlag M, Boender J, Ünlü B, Reitsma PH, Theme 1: Pathogenesis of venous thromboembolism (and post-thrombotic syndrome). THROMB RES 2015;136 (Suppl. 1):S3-S7 [PubMed]
  • van der Pol E. Detection of extracellular vesicles: size does matter. S.l.: s.n.; 2015. 222p. ISBN 9789462950696 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): van Leeuwen AGJM, Sturk A; copromotor(s): Nieuwland R)
  • van Es N, Bleker S, Sturk A, Nieuwland R, Clinical Significance of Tissue Factor-Exposing Microparticles in Arterial and Venous Thrombosis. SEMIN THROMB HEMOST 2015;41 (7):718-727 [PubMed]
  • Yuana Y, Böing AN, Grootemaat AE, van der Pol E, Hau CM, Cizmar P, Buhr E, Sturk A, Nieuwland R, Handling and storage of human body fluids for analysis of extracellular vesicles. J EXTRACELL VESICLES 2015;4:29260 [PubMed]

2014

  • Böing AN, van der Pol E, Grootemaat AE, Coumans FAW, Sturk A, Nieuwland R, Single-step isolation of extracellular vesicles by size-exclusion chromatography. J EXTRACELL VESICLES 2014;3:23430 [PubMed]
  • Coumans FAW, van der Pol E, Böing AN, Hajji N, Sturk G, van Leeuwen TG, Nieuwland R, Reproducible extracellular vesicle size and concentration determination with tunable resistive pulse sensing. J EXTRACELL VESICLES 2014;3:25922 [PubMed]
  • de Jong JSSG, Nieuwland R, Meijers JCM, Korporaal SJ, Akkerman JWN, Wilde AAAM, Dekker LRC, Altered platelet contents in survivors of early ischemic ventricular fibrillation: preliminary findings. PLATELETS 2014;25 (1):71-74 [PubMed]
  • Horjus DL, Nieuwland R, Boateng KB, Schaap MCL, van Montfrans GA, Clark JF, Sturk A, Brewster LM, Creatine kinase inhibits ADP-induced platelet aggregation. SCI REP-UK 2014;4:6551 [PubMed]
  • Majoor CJ , van de Pol MA, Kamphuisen PW, Meijers JCM, Molenkamp R, Wolthers KC, van der Poll T, Nieuwland R, Johnston SL, Sterk PJ, Bel EHD, Lutter R, van der Sluijs KF, Evaluation of coagulation activation after rhinovirus infection in patients with asthma and healthy control subjects: an observational study. RESP RES 2014;15 (1):14 [PubMed]
  • Tersteeg C, Heijnen HF, Eckly A, Pasterkamp G, Urbanus RT, Maas C, Hoefer IE, Nieuwland R, Farndale RW, Gachet C, de Groot PG, Roest M, FLow-Induced PRotrusions ( FLIPRs) A Platelet-Derived Platform for the Retrieval of Microparticles by Monocytes and Neutrophils. CIRC RES 2014;114 (5):780-791 [PubMed]
  • van der Pol E, Coumans FAW, Grootemaat AE, Gardiner C, Sargent IL, Harrison P, Sturk A, van Leeuwen TG, Nieuwland R, Particle size distribution of exosomes and microvesicles determined by transmission electron microscopy, flow cytometry, nanoparticle tracking analysis, and resistive pulse sensing. J THROMB HAEMOST 2014;12 (7):1182-1192 [PubMed]
  • van der Pol E, Coumans FAW, Sturk A, Nieuwland R, van Leeuwen TG, Refractive Index Determination of Nanoparticles in Suspension Using Nanoparticle Tracking Analysis. NANO LETT 2014;14 (11):6195-6201 [PubMed]
  • van Es N, Sturk A, Middeldorp S, Nieuwland R, Effects of cancer on platelets. SEMIN ONCOL 2014;41 (3):311-318 [PubMed]
  • Varga Z, Yuana Y, Grootemaat AE, van der Pol E, Gollwitzer C, Krumrey M, Nieuwland R, Towards traceable size determination of extracellular vesicles. J EXTRACELL VESICLES 2014;3:23298 [PubMed]
  • Yuana Y, Levels J, Grootemaat A , Sturk A, Nieuwland R, Co-isolation of extracellular vesicles and high-density lipoproteins using density gradient ultracentrifugation. J EXTRACELL VESICLES 2014;3:23262 [PubMed]

2013

  • Böing AN, Stap J, Hau CM, Afink GB, Ris-Stalpers C, Reits EA, Sturk A, van Noorden CJF, Nieuwland R, Active caspase-3 is removed from cells by release of caspase-3-enriched vesicles. BBA-MOL CELL RES 2013;1833 (8):1844-1852 [PubMed]
  • de Peuter OR, Verberne HJ, Kok WE, van den Bogaard B, Schaap MC, Nieuwland R, Meijers JCM, Somsen GA, Bakx A, Kamphuisen PW, Differential effects of nonselective versus selective β-blockers on cardiac sympathetic activity and hemostasis in patients with heart failure. J NUCL MED 2013;54 (10):1733-1739 [PubMed]
  • de Stoppelaar SF, van't Veer C, van den Boogaard FE, Nieuwland R, Hoogendijk AJ, de Boer OJ, Roelofs JJTH, van der Poll T, Protease activated receptor 4 limits bacterial growth and lung pathology during late stage Streptococcus pneumoniae induced pneumonia in mice. THROMB HAEMOSTASIS 2013;110 (3):582-592 [PubMed]
  • Franz C, Böing AN, Hau CM, Montag M, Strowitzki T, Nieuwland R, Toth B, Procoagulant tissue factor-exposing vesicles in human seminal fluid. J REPROD IMMUNOL 2013;98 (1-2):45-51 [PubMed]
  • Kleinjan A. Venous thrombosis in cancer patients: prediction, diagnosis and management. s.l.: s.n.; 2013. 225p. ISBN 9789461823175 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Büller HR, Kamphuisen PW; copromotor(s): Nieuwland R, Di Nisio M)
  • Smit KF, Oei GTML, Brevoord D, Stroes ES, Nieuwland R, Schlack WS, Hollmann MW, Weber NC, Preckel B, Helium induces preconditioning in human endothelium in vivo. ANESTHESIOLOGY 2013;118 (1):95-104 [PubMed]
  • van der Pol E, Coumans F, Varga Z, Krumrey M, Nieuwland R, Innovation in detection of microparticles and exosomes. J THROMB HAEMOST 2013;11 (Suppl. 1):36-45 [PubMed]
  • van Rijsingen IAW, Bakker A, Azim D, Hermans-van Ast JF, van der Kooi AJ, van Tintelen JP, van den Berg MP, Christiaans I, Lekanne dit Deprez RH, Wilde AAM, Zwinderman AH, Meijers JCM, Grootemaat AE, Nieuwland R, Pinto YM, Pinto-Sietsma SJ, Lamin A/C mutation is independently associated with an increased risk of arterial and venous thromboembolic complications. INT J CARDIOL 2013;168 (1):472-477 [PubMed]
  • Yuana Y, Sturk A, Nieuwland R, Extracellular vesicles in physiological and pathological conditions. BLOOD REV 2013;27 (1):31-39 [PubMed]
  • Zakhrabova-Zwiauer OM, Verkerk AO, de Jong JSSG, Sturk A, Nieuwland R, Tan HL, Acetylsalicylic acid prevents platelet-induced proarrhythmic effects on intracellular Ca2+ homeostasis in ventricular myocytes. INT J CARDIOL 2013;167 (1):303-305 [PubMed]

2012

  • Kalra H, Simpson RJ, Ji H, Aikawa E, Altevogt P, Askenase P, Bond VC, Borràs FE, Breakefield X, Budnik V, Buzas E, Camussi G, Clayton A, Cocucci E, Falcon-Perez JM, Gabrielsson S, Gho YS, Gupta D, Harsha HC, Hendrix A, Hill AF, Inal JM, Jenster G, Krämer-Albers EM, Lim SK, Llorente A, Lötvall J, Marcilla A, Mincheva-Nilsson L, Nazarenko I, Nieuwland R, Nolte-'t Hoen ENM, Pandey A, Patel T, Piper MG, Pluchino S, Prasad TSK, Rajendran L, Raposo G, Record M, Reid GE, Sánchez-Madrid F, Schiffelers RM, Siljander P, Stensballe A, Stoorvogel W, Taylor D, Thery C, Valadi H, van Balkom BWM, Vázquez J, Vidal M, Wauben MHM, Yáñez-Mó M, Zoeller M, Mathivanan S, Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation. PLOS BIOL 2012;10 (12):e1001450 [PubMed]
  • Kleinjan A, Böing AN, Sturk A, Nieuwland R, Microparticles in vascular disorders: How tissue factor-exposing vesicles contribute to pathology and physiology. THROMB RES 2012;130 (1):S71-S73 [PubMed]
  • Lemkes BA, Bähler L, Kamphuisen PW, Stroobants AK, van den Dool EJ, Hoekstra JB, Nieuwland R, Gerdes VE, Holleman F, The influence of aspirin dose and glycemic control on platelet inhibition in patients with type 2 diabetes mellitus. J THROMB HAEMOST 2012;10 (4):639-646 [PubMed]
  • Lok CAR, Snijder KS, Nieuwland R, van der Post JAM, de Vos P, Faas MM, Microparticles of Pregnant Women and Preeclamptic Patients Activate Endothelial Cells in the Presence of Monocytes. AM J REPROD IMMUNOL 2012;67 (3):206-215 [PubMed]
  • Nieuwland R, van der Pol E, Gardiner C, Sturk A. Platelet-Derived Microparticles in: Michelson AD, editor. Platelets. 3rd ed. San Diego: Academic Press; 2012., p. 453-467
  • Rank A, Liebhardt S, Zwirner J, Burges A, Nieuwland R, Toth B, Circulating Microparticles in Patients with Benign and Malignant Ovarian Tumors. ANTICANCER RES 2012;32 (5):2009-2014 [PubMed]
  • Rank A, Nieuwland R, Nikolajek K, Rösner S, Wallwiener LM, Hiller E, Toth B, Hormone replacement therapy leads to increased plasma levels of platelet derived microparticles in postmenopausal women. ARCH GYNECOL OBSTET 2012;285 (4):1035-1041 [PubMed]
  • Rank A, Nieuwland R, Roesner S, Nikolajek K, Hiller E, Toth B, Climacteric Lowers Plasma Levels of Platelet-Derived Microparticles: A Pilot Study in Pre-versus Postmenopausal Women. ACTA HAEMATOL-BASEL 2012;128 (1):53-59 [PubMed]
  • Sturk A, Nieuwland R, Cell-derived vasicles in health and disease. NED TIJDSCHR KLIN CHEM LABORATORIUMGENEESKD 2012;37:65-68
  • Tushuizen ME. Postprandial dysmetabolism and cell-derived microparticles as cardiovascular risk factors in metabolic syndrome and type 2 diabetes mellitus. s.l.: s.n.; 2012. -p. Proefschrift VU, Diabetes Centrum, afd Interne Geneeeskunde. (Promotor(s): Diamant M, Sturk A; copromotor(s): Nieuwland R)
  • Tushuizen ME, Diamant M, Peypers EG, Hoek FJ, Heine RJ, Sturk A, Nieuwland R, Postprandial changes in the phospholipid composition of circulating microparticles are not associated with coagulation activation. THROMB RES 2012;130 (1):115-121 [PubMed]
  • van den Akker J, van Weert A, Afink G, Bakker ENTP, van der Pol E, Böing AN, Nieuwland R, VanBavel E, Transglutaminase 2 is secreted from smooth muscle cells by transamidation-dependent microparticle formation. AMINO ACIDS 2012;42 (2-3):961-973 [PubMed]
  • van der Pol E, Böing AN, Harrison P, Sturk A, Nieuwland R, Classification, Functions, and Clinical Relevance of Extracellular Vesicles. PHARMACOL REV 2012;64 (3):676-705 [PubMed]
  • van der Pol E, van Gemert MJC, Sturk A, Nieuwland R, van Leeuwen TG, Single vs. swarm detection of microparticles and exosomes by flow cytometry. J THROMB HAEMOST 2012;10 (5):919-930 [PubMed]
  • van Doormaal FF, Kleinjan A, Berckmans RJ, Mackman N, Manly D, Kamphuisen PW, Richel DJ, Büller HR, Sturk A, Nieuwland R, Coagulation activation anc microparticle-associated coagulant activity in cancer patients An exploratory prospective study. THROMB HAEMOSTASIS 2012;108 (1):160-165 [PubMed]

2011

  • Ayers L, Kohler M, Harrison P, Sargent I, Dragovic R, Schaap M, Nieuwland R, Brooks SA, Ferry B, Measurement of circulating cell-derived microparticles by flow cytometry: Sources of variability within the assay. THROMB RES 2011;127 (4):370-377 [PubMed]
  • Berckmans RJ, Sturk A, van Tienen LM, Schaap MCL, Nieuwland R, Cell-derived vesicles exposing coagulant tissue factor in saliva. BLOOD 2011;117 (11):3172-3180 [PubMed]
  • Biró E, van den Goor JM, de Mol BA, Schaap MC, Ko LY, Sturk A, Hack CE, Nieuwland R, Complement activation on the surface of cell-derived microparticles during cardiac surgery with cardiopulmonary bypass - is retransfusion of pericardial blood harmful?. PERFUSION-UK 2011;26 (1):21-29 [PubMed]
  • Böing AN. Microparticles. Mediators of cellular and environmental homeostasis. s.l.: s.n.; 2011. 209p. ISBN 9789491211126 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Sturk A; copromotor(s): Nieuwland R)
  • de Jong JSSG, Verkerk AO, van Borren MMGJ, Zakhrabova-Zwiauer OM, Nieuwland R, Meijers JCM, Akkerman JWN, Wilde AAM, Tan HL, Dekker LRC, Activated human platelet products induce proarrhythmic effects in ventricular myocytes. J MOL CELL CARDIOL 2011;51 (3):347-356 [PubMed]
  • Juffermans NP, Prins DJ, Vlaar APJ, Nieuwland R, Binnekade JM, TRANSFUSION-RELATED RISK OF SECONDARY BACTERIAL INFECTIONS IN SEPSIS PATIENTS: A RETROSPECTIVE COHORT STUDY. SHOCK 2011;35 (4):355-359 [PubMed]
  • Nieuwland R, van der Post JAM, Lok CAR, Kenter G, Sturk A, Microparticles and exosomes in gynecologic neoplasias. SEMIN THROMB HEMOST 2011;37 (1):95 [PubMed]
  • Rank A, Nieuwland R, Crispin A, Grützner S, Iberer M, Toth B, Pihusch R, Clearance of platelet microparticles in vivo. PLATELETS 2011;22 (2):111-116 [PubMed]
  • Rank A, Nieuwland R, Delker R, Pihusch V, Wilkowski R, Toth B, Kolb HJ, Pihusch R, Surveillance of megakaryocytic function by measurement of CD61-exposing microparticles in allogeneic hematopoietic stem cell recipients. CLIN TRANSPLANT 2011;25 (3):E233-E242 [PubMed]
  • Rank A, Nieuwland R, Liebhardt S, Iberer M, Grützner S, Toth B, Pihusch R, Apheresis platelet concentrates contain platelet-derived and endothelial cell-derived microparticles. VOX SANG 2011;100 (2):179-186 [PubMed]
  • Rank A, Nieuwland R, Toth B, Pihusch V, Delker R, Hiller E, Kolb HJ, Pihusch R, Microparticles for diagnosis of graft-versus-host disease after allogeneic stem transplantation. TRANSPLANTATION 2011;92 (2):244-250 [PubMed]
  • Tushuizen ME, Diamant M, Sturk A, Nieuwland R, Cell-Derived Microparticles in the Pathogenesis of Cardiovascular Disease Friend or Foe?. ARTERIOSCL THROM VAS 2011;31 (1):4-9 [PubMed]
  • van der Post JAM, Lok CAR, Boer K, Sturk A, Sargent IL, Nieuwland R, The Functions of Microparticles in Pre-Eclampsia. SEMIN THROMB HEMOST 2011;37 (2):146-152 [PubMed]
  • Vlaar APJ, Kulik W, Nieuwland R, Peters CP, Tool ATJ, van Bruggen R, Juffermans NP, de Korte D, Accumulation of bioactive lipids during storage of blood products is not cell but plasma derived and temperature dependent. TRANSFUSION 2011;51 (11):2358-2366 [PubMed]

2010

  • Liebhardt S, Ditsch N, Nieuwland R, Rank A, Jeschke U, VON Koch F, Friese K, Toth B, CEA-, Her2/neu-, BCRP- and Hsp27-positive Microparticles in Breast Cancer Patients. ANTICANCER RES 2010;30 (5):1707-1712 [PubMed]
  • Nieuwland R, Sturk A, Why do cells release vesicles?. THROMB RES 2010;125 (Suppl. 1):S49-S51 [PubMed]
  • Nieuwland R, van der Post JAM, Lok Gemma CAR, Kenter G, Sturk A, Microparticles and Exosomes in Gynecologic Neoplasias. SEMIN THROMB HEMOST 2010;36 (8):925-929 [PubMed]
  • Rank A, Nieuwland R, Delker R, Köhler A, Toth B, Pihusch V, Wilkowski R, Pihusch R, Cellular origin of platelet-derived microparticles in vivo. THROMB RES 2010;126 (4):E255-E259 [PubMed]
  • van der Pol E, Hoekstra AG, Sturk A, Otto C, van Leeuwen TG, Nieuwland R, Optical and non-optical methods for detection and characterization of microparticles and exosomes. J THROMB HAEMOST 2010;8 (12):2596-2607 [PubMed]
  • van der Zee PM. Biomarkers in ischemic cardiiac syndromes. s.l.: s.n.; 2010. 161p. ISBN 9789461080875 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): de Winter RJ, Sturk A; copromotor(s): Nieuwland R, Verberne HJ)
  • van der Zee PM, Biró E, Trouw LA, Ko Y, de Winter RJ, Hack CE, Sturk A, Nieuwland R, C-reactive protein in myocardial infarction binds to circulating microparticles but is not associated with complement activation. CLIN IMMUNOL 2010;135 (3):490-495 [PubMed]
  • van Eijk IC, Tushuizen ME, Sturk A, Dijkmans BAC, Boers M, Voskuyl AE, Diamant M, Wolbink GJ, Nieuwland R, Nurmohamed MT, Circulating microparticles remain associated with complement activation despite intensive anti-inflammatory therapy in early rheumatoid arthritis. ANN RHEUM DIS 2010;69 (7):1378-1382 [PubMed]
  • Vlaar APJ, Hofstra JJ, Kulik W, van Lenthe H, Nieuwland R, Schultz MJ, Levi MM, Roelofs JJTH, Tool ATJ, de Korte D, Juffermans NP, Supernatant of stored platelets causes lung inflammation and coagulopathy in a novel in vivo transfusion model. BLOOD 2010;116 (8):1360-1368 [PubMed]
  • Vlaar APJ, Hofstra JJ, Levi M, Kulik W, Nieuwland R, Tool ATJ, Schultz MJ, de Korte D, Juffermans NP, Supernatant of Aged Erythrocytes Causes Lung Inflammation and Coagulopathy in a "Two-Hit" In Vivo Syngeneic Transfusion Model. ANESTHESIOLOGY 2010;113 (1):92-103 [PubMed]

2009

  • Böing AN, Hau CM, Sturk A, Nieuwland R, Human alternatively spliced tissue factor is not secreted and does not trigger coagulation. J THROMB HAEMOST 2009;7 (8):1423-1426 [PubMed]
  • Gerrits AJ, Koekman CA, Yildirim C, Nieuwland R, Akkerman JWN, Insulin inhibits tissue factor expression in monocytes. J THROMB HAEMOST 2009;7 (1):198-205 [PubMed]
  • Kramer MCA, Nieuwland R, Sturk A, de Winter RJ, Routinebepaling bloedplaatjesremming niet zinvol. Bij gebruik acetylsalicylzuur of clopidogrel. NED TIJDSCHR GENEESKD 2009;153 (5):190-195 [PubMed]
  • Lok CAR, Jebbink J, Nieuwland R, Faas MM, Boer K, Sturk A, van der Post JAM, Leukocyte Activation and Circulating Leukocyte-Derived Microparticles in Preeclampsia. AM J REPROD IMMUNOL 2009;61 (5):346-359 [PubMed]
  • Lok CAR, Nieuwland R, Boer K, Sturk A, Post JAMvd, The clinics and etiology of preeclampsia. CURR WOMENS HEALTH REV 2009;5:157-166
  • Nicu EA, van der Velden U, Nieuwland R, Everts V, Loos BG, Elevated platelet and leukocyte response to oral bacteria in periodontitis. J THROMB HAEMOST 2009;7 (1):162-170 [PubMed]
  • Papapanagiotou D, Nicu EA, Bizzarro S, Gerdes VEA, Meijers JC, Nieuwland R, van der Velden U, Loos BG, Periodontitis is associated with platelet activation. ATHEROSCLEROSIS 2009;202 (2):605-611 [PubMed]
  • Reuwer AQ, Nieuwland R, Fernandez I, Goffin V, van Tiel CM, Schaap MCL, Berckmans RJ, Kastelein JJP, Twickler MTB, Prolactin does not affect human platelet aggregation or secretion. THROMB HAEMOSTASIS 2009;101 (6):1119-1127 [PubMed]
  • van Beers EJ, Schaap MCL, Berckmans RJ, Nieuwland R, Sturk A, van Doormaal FF, Meijers JCM, Biemond BJ, Circulating erythrocyte-derived microparticles are associated with coagulation activation in sickle cell disease. HAEMATOLOGICA 2009;94 (11):1513-1519 [PubMed]
  • van Doormaal FF, Kleinjan A, Di Nisio M, Büller HR, Nieuwland R, Cell-derived microvesicles and cancer. NETH J MED 2009;67 (7):266-273 [PubMed]
  • Vedder AC, Biró E, Aerts JMFG, Nieuwland R, Sturk G, Hollak CEM, Plasma markers of coagulation and endothelial activation in Fabry disease: impact of renal impairment. NEPHROL DIAL TRANSPL 2009;24 (10):3074-3081 [PubMed]

2008

  • Biró E. Cell-derived microparticles. Composition and function. s.l.: s.n.; 2008. 257p. ISBN 9789090235721 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Sturk A; copromotor(s): Nieuwland R)
  • Biró E , Tak PP, Sturk A, Hack CE, Nieuwland R, Targeting complement in rheumatoid arthritis. CURR RHEUMATOL REV 2008;4:235-245
  • Böing AN, Hau CM, Sturk A, Nieuwland R, Platelet microparticles contain active caspase 3. PLATELETS 2008;19 (2):96-103 [PubMed]
  • Buimer M, Lok CAR, Nieuwland R, Ris-Stalpers C, van der Post JAM, Placental corticotrophin-releasing hormone mRNA and microparticles in maternal plasma are not measures of placental shedding of debris: a rebuttal. J THROMB HAEMOST 2008;6 (10):1837-8; author reply 1838-9 [PubMed]
  • Diamant M, Tushuizen ME, Abid-Hussein MN, Hau CM, Böing AN, Sturk A, Nieuwland R, Simvastatin-induced endothelial cell detachment and microparticle release are prenylation dependent. THROMB HAEMOSTASIS 2008;100 (3):489-497 [PubMed]
  • Hussein MNA. Endothelial cell-derived microparticles. s.l.: s.n.; 2008. 169p. ISBN 9789090224831 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Sturk A; copromotor(s): Nieuwland R)
  • Hussein MNA, Boeing AN, Biro E, Hoek FJ, Vogel GMT, Meuternan DG, Sturk A, Nieuwland R, Phospholipid composition of in vitro endothelial microparticles and their in vivo thrombogenic properties. THROMB RES 2008;121 (6):865-871 [PubMed]
  • Lok CA, Böing A, Sargent I, Sooranna S, van der Post J, Nieuwland R, Sturk A, Circulating Platelet-derived and Placenta-derived Microparticles Expose Flt-1 in Preeclampsia. REPROD SCI 2008;15 (10):1002-1010 [PubMed]
  • Lok CAR. Microparticles in pregnancy and preeclampsia. s.l.: s.n.; 2008. 215p. ISBN 9789090229362 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): van der Post JAM, Sturk A; copromotor(s): Boer K, Nieuwland R)
  • Lok CAR, van der Post JAM, Sargent IL, Hau CM, Sturk A, Boer K, Nieuwland R, Changes in microparticle numbers and cellular origin during pregnancy and preeclampsia. HYPERTENS PREGNANCY 2008;27 (4):344-360 [PubMed]
  • Nieuwland R, Cellular origin of microparticles exposing tissue factor in cancer: a mixed double?. J THROMB HAEMOST 2008;6 (9):1514-1516 [PubMed]
  • Nieuwland R, Stroobants AK, Sturk A, Hemostase anno 2008. NED TIJDSCHR KLIN CHEM LABORATORIUMGENEESKD 2008;33 (4):223-228
  • Stroobants AK, Nieuwland R, Sturk A, Hemostase anno 2008. TROMNIBUS 2008;3:45-52
  • Toth B, Nieuwland R, Kern M, Rogenhofer N, Berkmans R, Rank A, Lohse P, Friese K, Thaler CJ, Systemic changes in haemostatic balance are not associated with increased levels of circulating microparticles in women with recurrent spontaneous abortion. AM J REPROD IMMUNOL 2008;59 (2):159-166 [PubMed]
  • Toth B, Nieuwland R, Liebhardt S, Ditsch N, Steinig K, Stieber P, Rank A, Göhring P, Thaler CJ, Friese K, Bauerfeind I, Circulating microparticles in breast cancer patients: a comparative analysis with established biomarkers. ANTICANCER RES 2008;28 (2A):1107-1112 [PubMed]
  • van den Goor JMMH. Clinical aspects of blood activation in open-heart surgery. s.l.: s.n.; 2008. 161p. ISBN 9789090235547 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Eijsman L, de Mol BAJM; copromotor(s): Nieuwland R, van Oeveren W)
  • van den Goor J, Saxby B, Tijssen J, Wesnes K, de Mol B, Nieuwland R, Improvement of cognitive test performance in patients undergoing primary CABG and other CPB-assisted cardiac procedures. PERFUSION-UK 2008;23 (5):267-273 [PubMed]

2007

  • Abid Hussein MN, Böing AN, Sturk A, Hau CM, Nieuwland R, Inhibition of microparticle release triggers endothelial cell apoptosis and detachment. THROMB HAEMOSTASIS 2007;98 (5):1096-1107 [PubMed]
  • Biró E, Lok CAR, Hack CE, van der Post JAM, Schaap MCL, Sturk A, Nieuwland R, Cell-derived microparticles and complement activation in preeclampsia versus normal pregnancy. PLACENTA 2007;28 (8-9):928-935 [PubMed]
  • Biro E, Nieuwland R, Hack CE, Sturk A, Complement activatie op micropartikels. NED TIJDSCHR KLIN CHEM LABORATORIUMGENEESKD 2007;32:170-173
  • Biro E, Nieuwland R, Tak PP, Pronk LM, Schaap MCL, Sturk A, Hack CE, Activated complement components and complement activator molecules on the surface of cell-derived microparticles in patients with rheumatoid arthritis and healthy individuals. ANN RHEUM DIS 2007;66 (8):1085-1092 [PubMed]
  • Boing AN, Sturk A, Nieuwland R, Microparticles and thrombosis. INT REV THROMB 2007;2:29-35
  • Lok CAR, Nieuwland R, Sturk A, Hau CM, Boer K, VanBavel E, Vanderpost JAM, Microparticle-associated P-selectin reflects platelet activation in preeclampsia. PLATELETS 2007;18 (1):68-72 [PubMed]
  • Nieuwland R, Sturk A, Aspirine en clopidogrel resistentie. TROMNIBUS 2007;35:47-51
  • Nieuwland R, Sturk A. Platet-derived microparticles in: Michelson AD, editor. Platelets [second edition]. New York: Academic Press; 2007., p. 403-413
  • Toth B, Lok CAR, Böing A, Diamant M, van der Post JAM, Friese K, Nieuwland R, Microparticles and exosomes: impact on normal and complicated pregnancy. AM J REPROD IMMUNOL 2007;58 (5):389-402 [PubMed]
  • Toth B, Nikolajek K, Rank A, Nieuwland R, Lohse P, Pihusch V, Friese K, Thaler CJ, Gender-specific and menstrual cycle dependent differences in circulating microparticles. PLATELETS 2007;18 (7):515-521 [PubMed]
  • Tushuizen ME, Nieuwland R, Rustemeijer C, Hensgens BE, Sturk A, Heine RJ, Diamant M, Elevated endothelial microparticles following consecutive meals are associated with vascular endothelial dysfunction in type 2 diabetes. DIABETES CARE 2007;30 (3):728-730 [PubMed]
  • van den Goor JM, Nieuwland R, Rutten PM, Tijssen JG, Hau C, Sturk A, Eijsman L, de Mol BA, Retransfusion of pericardial blood does not trigger systemic coagulation during cardiopulmonary bypass. EUR J CARDIO-THORAC 2007;31 (6):1029-1036 [PubMed]
  • van den Goor JM, Nieuwland R, van Oeveren W, Rutten PM, Tijssen JG, Hau CM, Sturk A, Eijsman L, de Mol BA, Cell Saver device efficiently removes cell-derived microparticles during cardiac surgery. J THORAC CARDIOV SUR 2007;134 (3):798-799 [PubMed]

2006

  • de Pont ACJM, Bouman CSC, Bakhtiari K, Schaap MCL, Nieuwland R, Sturk A, Hutten BA, de Jonge E, Vroom MB, Meijers JCM, Büller HR, Predilution versus postdilution during continuous venovenous hemofiltration: a comparison of circuit thrombogenesis. ASAIO J 2006;52 (4):416-422 [PubMed]
  • Lok CAR, Böing AN, Reitsma PH, van der Post JAM, van Bavel E, Boer K, Sturk A, Nieuwland R, Expression of inflammation-related genes in endothelial cells is not directly affected by microparticles from preeclamptic patients. J LAB CLIN MED 2006;147 (6):310-320 [PubMed]
  • Nieuwland R, Sturk A. Platelet-derived microparticles in: Michelson AD, editor. Platelets. Burlington MA: Academic Press; 2006., p. 403-413
  • Tushuizen ME, Nieuwland R, Scheffer PG, Sturk A, Heine RJ, Diamant M, Two consecutive high-fat meals affect endothelial-dependent vasodilation, oxidative stress and cellular microparticles in healthy men. J THROMB HAEMOST 2006;4 (5):1003-1010 [PubMed]
  • van der Zee PM, Biró E, Ko Y, de Winter RJ, Hack CE, Sturk A, Nieuwland R, P-selectin- and CD63-exposing platelet microparticles reflect platelet activation in peripheral arterial disease and myocardial infarction. CLIN CHEM 2006;52 (4):657-664 [PubMed]

2005

  • Abid Hussein MN, Nieuwland R, Hau CM, Evers LM, Meesters EW, Sturk A, Cell-derived microparticles contain caspase 3 in vitro and in vivo. J THROMB HAEMOST 2005;3 (5):888-896 [PubMed]
  • Berckmans RJ, Nieuwland R, Kraan MC, Schaap MCL, Pots D, Smeets TJM, Sturk A, Tak PP, Synovial microparticles from arthritic patients modulate chemokine and cytokine release by synoviocytes. ARTHRITIS RES THER 2005;7 (3):R536-R544 [PubMed]
  • Biró E, Akkerman JWN, Hoek FJ, Gorter G, Pronk LM, Sturk A, Nieuwland R, The phospholipid composition and cholesterol content of platelet-derived microparticles: a comparison with platelet membrane fractions. J THROMB HAEMOST 2005;3 (12):2754-2763 [PubMed]
  • Onland W, Böing AN, Meijer AB, Schaap MCL, Nieuwland R, Haasnoot K, Sturk A, Peters M, Congenital deficiency of factor XIII caused by two missense mutations in a Dutch family. HAEMOPHILIA 2005;11 (5):539-547 [PubMed]

2004

  • Berckmans RJ. Microparticles, coagulation and inflammation. S.l.: s.n.; 2004. 198p. ISBN 90-9018498-8 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Hack CE, Sturk A; copromotor(s): Nieuwland R)
  • Diamant M, Tushuizen ME, Sturk A, Nieuwland R, Cellulaire micropartikels en vaatschade. II. Functionele eigenschappen en klinische betekenis. NED TIJDSCHR GENEESKD 2004;148 (28):1380-1384 [PubMed]
  • Diamant M, Tushuizen ME, Sturk A, Nieuwland R, Cellulaire micropartikels en vaatschade. I. Structuur, detectie en ontstaanswijze. NED TIJDSCHR GENEESKD 2004;148 (28):1376-1380 [PubMed]
  • Diamant M, Tushuizen ME, Sturk A, Nieuwland R, Cellular microparticles: new players in the field of vascular disease?. EUR J CLIN INVEST 2004;34 (6):392-401 [PubMed]
  • Jy W, Horstman LL, Jimenez JJ, Ahn YS, Biró E, Nieuwland R, Sturk A, Dignat-George F, Sabatier F, Camoin-Jau L, Sampol J, Hugel B, Zobairi F, Freyssinet JM, Nomura S, Shet AS, Key NS, Hebbel RP, Measuring circulating cell-derived microparticles. J THROMB HAEMOST 2004;2 (10):1842-1851 [PubMed]
  • van den Goor J, Nieuwland R, van den Brink A , van Oeveren W, Rutten P, Tijssen J, Eijsman L, Reduced complement activation during cardiopulmonary bypass does not affect the postoperative acute phase response. EUR J CARDIO-THORAC 2004;26 (5):926-931 [PubMed]

2003

  • Abid Hussein MN, Meesters EW, Osmanovic N, Romijn FPHTM, Nieuwland R, Sturk A, Antigenic characterization of endothelial cell-derived microparticles and their detection ex vivo. J THROMB HAEMOST 2003;1 (11):2434-2443 [PubMed]
  • Biró E, Sturk-Maquelin KN, Vogel GMT, Meuleman DG, Smit MJ, Hack CE, Sturk A, Nieuwland R, Human cell-derived microparticles promote thrombus formation in vivo in a tissue factor-dependent manner. J THROMB HAEMOST 2003;1 (12):2561-2568 [PubMed]
  • Maquelin KN. Platelet activation and microparticles in the pericardial cavity during cardiopulmonary bypass. S.l.: s.n.; 2003. 141p. ISBN 90-9016721-8 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Eijsman L, Hack CE; copromotor(s): Nieuwland R)
  • Sturk-Maquelin KN, Nieuwland R, Romijn FPHTM, Eijsman L, Hack CE, Sturk A, Pro- and non-coagulant forms of non-cell-bound tissue factor in vivo. J THROMB HAEMOST 2003;1 (9):1920-1926 [PubMed]
  • van den Goor JM, van den Brink A, Nieuwland R, van Oeveren W, Rutten PM, Tepaske R, Tijssen JG, Sturk A, de Mol BA, Eijsman L, Generation of platelet-derived microparticles in patients undergoing cardiac surgery is not affected by complement activation. J THORAC CARDIOV SUR 2003;126 (4):1101-1106 [PubMed]
  • Vanlandschoot P, van Houtte F, Hoek F, Nieuwland R, Leroux-Roels G, Saccharomyces cerevisiae-derived HBsAg preparations differ in their attachment to monocytes, immune-suppressive potential, and T-cell immunogenicity. J MED VIROL 2003;70 (4):513-519 [PubMed]
  • VanWijk MJ, VanBavel E, Sturk A, Nieuwland R, Microparticles in cardiovascular diseases. CARDIOVASC RES 2003;59 (2):277-287 [PubMed]

2002

  • Berckmans RJ, Nieuwland R, Tak PP, Böing AN, Romijn FPHTM, Kraan MC, Breedveld FC, Hack CE, Sturk A, Cell-derived microparticles in synovial fluid from inflamed arthritic joints support coagulation exclusively via a factor VII-dependent mechanism. ARTHRITIS RHEUM-US 2002;46 (11):2857-2866 [PubMed]
  • Diamant M, Nieuwland R, Pablo RF, Sturk A, Smit JWA, Radder JK, Elevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus. CIRCULATION 2002;106 (19):2442-2447 [PubMed]
  • Knijff-Dutmer EAJ, Koerts J, Nieuwland R, Kalsbeek-Batenburg EM, van de Laar MAFJ, Elevated levels of platelet microparticles are associated with disease activity in rheumatoid arthritis. ARTHRITIS RHEUM-US 2002;46 (6):1498-1503 [PubMed]
  • Nauta AJ, Trouw LA, Daha MR, Tijsma O, Nieuwland R, Schwaeble WJ, Gingras AR, Mantovani A, Hack EC, Roos A, Direct binding of C1q to apoptotic cells and cell blebs induces complement activation. EUR J IMMUNOL 2002;32 (6):1726-1736 [PubMed]
  • VanWijk MJ, Boer K, Berckmans RJ, Meijers JCM, van der Post JAM, Sturk A, VanBavel E, Nieuwland R, Enhanced coagulation activation in preeclampsia: the role of APC resistance, microparticles and other plasma constituents. THROMB HAEMOSTASIS 2002;88 (3):415-420 [PubMed]
  • VanWijk MJ, Nieuwland R, Boer K, van der Post JAM, VanBavel E, Sturk A, Microparticle subpopulations are increased in preeclampsia: Possible involvement in vascular dysfunction?. AM J OBSTET GYNECOL 2002;187 (2):450-456 [PubMed]
  • VanWijk MJ, Svedas E, Boer K, Nieuwland R, VanBavel E, Kublickiene KR, Isolated microparticles, but not whole plasma, from women with preeclampsia impair endothelium-dependent relaxation in isolated myometrial arteries from healthy pregnant women. AM J OBSTET GYNECOL 2002;187 (6):1686-1693 [PubMed]
  • Weerheim AM, Kolb AM, Sturk A, Nieuwland R, Phospholipid composition of cell-derived microparticles determined by one-dimensional high-performance thin-layer chromatography. ANAL BIOCHEM 2002;302 (2):191-198 [PubMed]

2001

  • Berckmans RJ, Nieuwland R, Böing AN, Romijn FP, Hack CE, Sturk A, Cell-derived microparticles circulate in healthy humans and support low grade thrombin generation. THROMB HAEMOSTASIS 2001;85 (4):639-646 [PubMed]
  • Biró E , Nieuwland R, Wester JP, Haas FJ, Sturk A, Laboratoriumdiagnostiek van heparine-geïnduceerde trombocytopenie. TIJDSCHR BELG VER LAB TECHN 2001;28:5-15

2000

  • Biró E , Nieuwland R, Wester JP, Haas FJ, Sturk A, Laboratoriumdiagnostiek van heparine-geïnduceerde trombocytopenie. NED TIJDSCHR KLIN CHEM LABORATORIUMGENEESKD 2000;25:300-305
  • Maquelin KN, Nieuwland R, Lentjes EG, Böing AN, Mochtar B, Eijsman L, Sturk A, Aprotinin administration in the pericardial cavity does not prevent platelet activation. J THORAC CARDIOV SUR 2000;120 (3):552-557 [PubMed]
  • Nieuwland R, Berckmans RJ, McGregor S, Böing AN, Romijn FP, Westendorp RG, Hack CE, Sturk A, Cellular origin and procoagulant properties of microparticles in meningococcal sepsis. BLOOD 2000;95 (3):930-935 [PubMed]