Ing. B.D.M. Boeser-Nunnink publications

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Publications Ing. B.D.M. Boeser-Nunnink

Position
Laboratory technician
Main activities
Research
Specialisation
Molecular biology; Virology
Focus of research

Function of hiv

2018

  • Francesco DD, Verboeket SO, Underwood J, Bagkeris E, Wit FW, Mallon PWG, Winston A, Reiss P, Sabin CA [Contributors: Babalis D, Boffito M, Burgess L, Mallon P, Post F, Sabin CA, Sachikonye M, Winston A, Anderson J, Asboe D, Garvey L, Pozniak A, Vera J, Williams I, Clarke A, Bexley A, Richardson C, Kirk S, Gleig R, Bracchi M, Pagani N, Cerrone M, Bradshaw D, Ferretti F, Higgs C, Seah E, Fletcher S, Anthonipillai M, Moyes A, Deats K, Syed I, Matthews C, Fernando P, Chiwome C, Hardwick S, Mguni S, Clark R, Nevin-Dolan R, Pelluri S, Campbell L, Yurdakul S, Okumu S, Pollard L, Santana-Suarez B, Macken A, Ghavani-Kia B, Maher J, Byrne M, Flaherty A, Babu S, Otiko D, Phillips L, Laverick R, Beynon M, Salz AL, Severn A, Underwood J, Tembo L, Stott M, McDonald L, Dransfield F, Whitehouse A, Johnson M, Ngwu N, Hemat N, Jones M, Carroll A, Kinloch S, Youle M, Madge S, de Francesco D, Bagkeris E, Reiss P, Wit FWNM, van der Valk M, Schouten J , Kooij KW, van Zoest RA, Verheij E, Verboeket SO, Elsenga BC, Prins M, Schim van der Loeff MF , del Grande L, Olthof V, Dijkstra M, Zaheri S, Hillebregt MMJ, Ruijs YMC, Benschop DP, El Berkaoui A, Kootstra NA, Harskamp-Holwerda AM, Maurer I, Ruiz MMM, Girigorie AF, Boeser-Nunnink B, Zikkenheiner W, Janssen FR, Geerlings SE, Goorhuis A, Hovius JWR, Nellen FJB, van der Poll T, Prins JM, Wiersinga WJ, van Vugt M, de Bree G, van Eden J, van Hes AMH, Pijnappel FJJ, Weijsenfeld A, Smalhout S, van Duinen M, Hazenberg A, Postema PG, Bisschop PHLT, Serlie MJM, Lips P, Dekker E, van der Velde N, Willemsen JMR, Vogt L, Portegies P, Schmand BA, Geurtsen GJ , Verbraak FD, Demirkaya N , Visser I, Schadé A, Nieuwkerk PT, Langebeek N, van Steenwijk RP, Dijkers E, Majoie CBLM, Caan MWA, van Lunsen HW, Nievaard MAF, van den Born BJH, Stroes ESG, Mulder WMC, van Oorspronk S]] , Patterns of Co-occurring Comorbidities in People Living With HIV. OPEN FORUM INFECT DI 2018;5 (11):ofy272 [PubMed]
  • van Zoest RA, Underwood J, de Francesco D, Sabin CA, Cole JH, Wit FW, Caan MWA, Kootstra NA, Fuchs D, Zetterberg H, Majoie CBLM, Portegies P, Winston A, Sharp DJ, Gisslén M, Reiss P [Contributors: Reiss P, Winston A, Wit FW, Prins M, Schim van der Loeff MF , Schouten J , Schmand B, Geurtsen GJ , Sharp DJ, Caan MWA, Majoie C, Villaudy J, Berkhout B, Kootstra NA, Gisslén M, Pasternak A, Sabin CA, Guaraldi G, Bürkle A, Libert C, Franceschi C, Kalsbeek A, Fliers E, Hoeijmakers J, Pothof J, van der Valk M, Bisschop PH, Portegies P, Zaheri S, Burger D, Cole JH, Zikkenheiner W, Janssen FR, Underwood J, Kooij KW, van Zoest RA, Doyle N, Schim van der Loeff M, Schmand BA, Verheij E, Verboeket SO, Elsenga BC, Hillebregt MMJ, Ruijs YMC, Benschop DP, Tembo L, McDonald L, Stott M, Legg K, Lovell A, Erlwein O, Kingsley C, Norsworthy P, Mullaney S, Kruijer T, del Grande L, Olthof V, Visser GR, May L, Verbraak F, Demirkaya N , Visser I, Majoie CBLM, Su T, Leech R, Huguet J, Frankin E, van der Kuyl A, Weijer K, Siteur-van Rijnstra E, Harskamp-Holwerda AM, Maurer I, Mangas Ruiz MM, Girigorie AF, Boeser-Nunnink B, Bisschop PHLT, de Graaff-Teulen M, Dewaele S, Garagnani P, Pirazzini C, Capri M, Dall'Olio F, Chiricolo M, Salvioli S, Fuchs D, Zetterberg H, Weber D, Grune T, Jansen EHJM, de Francesco D, Sindlinger T, Oehlke S]] , Structural Brain Abnormalities in Successfully Treated HIV Infection: Associations With Disease and Cerebrospinal Fluid Biomarkers. J INFECT DIS 2018;217 (1):69-81 [PubMed]

2017

  • Booiman T, Wit FW, Maurer I, de Francesco D, Sabin CA, Harskamp AM, Prins M, Garagnani P, Pirazzini C, Franceschi C, Fuchs D, Gisslén M, Winston A, Reiss P, Kootstra NA [Contributors: Reiss P, Wit FWNM, Schouten J , Kooij KW, van Zoest RA, Elsenga BC, Janssen FR, Heidenrijk M, Zikkenheiner W, van der Valk M, Kootstra NA, Booiman T, Harskamp-Holwerda AM, Boeser-Nunnink B, Maurer I, Mangas Ruiz MM, Girigorie AF, Villaudy J, Frankin E, Pasternak A, Berkhout B, van der Kuyl T, Portegies P, Schmand BA, Geurtsen GJ , ter Stege JA, Klein Twennaar M, Majoie CBLM, Caan MWA, Su T, Weijer K, Bisschop PHLT, Kalsbeek A, Wezel M, Visser I, Ruhé HG, Franceschi C, Garagnani P, Pirazzini C, Capri M, Dall'Olio F, Chiricolo M, Salvioli S, Hoeijmakers J, Pothof J, Prins M, Martens M, Moll S, Berkel J, Totté M, Kovalev S, Gisslén M, Fuchs D, Zetterberg H, Winston A, Underwood J, McDonald L, Stott M, Legg K, Lovell A, Erlwein O, Doyle N, Kingsley C, Sharp DJ, Leech R, Cole JH, Zaheri S, Hillebregt MMJ, Ruijs YMC, Benschop DP, Burger D, de Graaff-Teulen M, Guaraldi G, Bürkle A, Sindlinger T, Moreno-Villanueva M, Keller A, Sabin C, de Francesco D, Libert C, Dewaele S]] , High Cellular Monocyte Activation in People Living With Human Immunodeficiency Virus on Combination Antiretroviral Therapy and Lifestyle-Matched Controls Is Associated With Greater Inflammation in Cerebrospinal Fluid. OPEN FORUM INFECT DI 2017;4 (3):ofx108 [PubMed]

2016

  • Cobos Jiménez V, Wit FWNM, Joerink M, Maurer I, Harskamp AM, Schouten J, Prins M, van Leeuwen EMM, Booiman T, Deeks SG, Reiss P, Kootstra NA [Contributors: Reiss P, Wit FWNM, van der Valk M, Schouten J , Kooij KW, van Zoest RA, Elsenga BC, Prins M, Martens M, Moll S, Berkel J, Totté M, Visser GR, Kovalev S, Zaheri S, Hillebregt MMJ, Ruijs YMC, Benschop DP, Reis P, Janssen FR, Heidenrijk M, Zikkenheiner W, Boumans L, Kootstra NA, Harskamp-Holwerda AM, Maurer I, Mangas Ruiz MM, Girigorie AF, Boeser-Nunnink B, Geerlings SE, Godfried MH, Goorhuis A, Hovius JWR, Nellen FJB, van der Meer JTM, van der Poll T, Prins JM, Wiersinga WJ, van Eden J, van Hes AMH, Mutschelknauss M, Nobel HE, Pijnappel FJJ, Westerman AM, de Jong J, Postema PG, Bisschop PHLT, Serlie MJM, Lips P, Dekker E, de Rooij SEJA, Willemsen JMR, Vogt L, Portegies P, Schmand BA, Geurtsen GJ , ter Stege JA, Klein Twennaar M, van Eck-Smit BLF, de Jong M, Richel DJ, Verbraak FD, Demirkaya N , Visser I, Ruhé HG, Nieuwkerk PT, van Steenwijk RP, Dijkers E, Majoie CBLM, Caan MWA, Su T, van Lunsen HW, Nievaard MAF, van den Born BJH, Stroes ESG, Mulder WMC]] , T-Cell Activation Independently Associates With Immune Senescence in HIV-Infected Recipients of Long-term Antiretroviral Treatment. J INFECT DIS 2016;214 (2):216-225 [PubMed]
  • Cornelissen M, Euler Z, van den Kerkhof TLGM, van Gils MJ, Boeser-Nunnink BDM, Kootstra NA, Zorgdrager F, Schuitemaker H, Prins JM, Sanders RW, van der Kuyl AC, The Neutralizing Antibody Response in an Individual with Triple HIV-1 Infection Remains Directed at the First Infecting Subtype. AIDS RES HUM RETROV 2016;32 (10-11):1135-1142 [PubMed]
  • Kooij KW, Wit FWNM, Booiman T, van der Valk M, Schim van der Loeff MF, Kootstra NA, Reiss P [Contributors: Reiss P, Wit FWNM, van der Valk M, Schouten J , Kooij KW, van Zoest RA, Verheij E, Elsenga BC, Prins M, Schim van der Loeff MF , Martens M, Moll S, Berkel J, Totté M, Visser GR, May L, Kovalev S, Newsum A, Dijkstra M, Zaheri S, Hillebregt MMJ, Ruijs YMC, Benschop DP, El Berkaoui A, Zikkenheiner W, Janssen FR, Kootstra NA, Harskamp-Holwerda AM, Maurer I, Booiman T, Ruiz MMM, Girigorie AF, Boeser-Nunnink B, Geerlings SE, Godfried MH, Goorhuis A, Hovius JWR, van der Meer JTM, Nellen FJB, van der Poll T, Prins JM, Wiersinga WJ, van Vugt M, de Bree G, van Eden J, van Hes AMH, Mutschelknauss M, Nobel HE, Pijnappel FJJ, Bijsterveld M, Weijsenfeld A, Smalhout S, de Jong J, Postema PG, Bisschop PHLT, Serlie MJM, Lips P, Dekker E, van der Velde N, Willemsen JMR, Vogt L, Portegies P, Schmand BA, Geurtsen GJ , Verbraak FD, Demirkaya N , Visser I, Schadé A, Nieuwkerk PT, Langebeek N, van Steenwijk RP, Dijkers E, Majoie CBLM, Caan MWA, Su T, van Lunsen HW, Nievaard MAF, van den Born BJH, Stroes ESG, Mulder WMC]] , Cigarette Smoking and Inflammation, Monocyte Activation, and Coagulation in HIV-Infected Individuals Receiving Antiretroviral Therapy, Compared With Uninfected Individuals. J INFECT DIS 2016;214 (12):1817-1821 [PubMed]
  • Ploquin MJ, Madec Y, Casrouge A, Huot N, Passaes C, Lécuroux C, Essat A, Boufassa F, Jacquelin B, Jochems SP, Petitjean G, Angin M, Gärtner K, Garcia-Tellez T, Noël N, Booiman T, Boeser-Nunnink BD, Roques P, Saez-Cirion A, Vaslin B, Dereudre-Bosquet N, Barré-Sinoussi F, Ghislain M, Rouzioux C, Lambotte O, Albert ML, Goujard C, Kootstra N, Meyer L, Müller-Trutwin MC, Elevated Basal Pre-infection CXCL10 in Plasma and in the Small Intestine after Infection Are Associated with More Rapid HIV/SIV Disease Onset. PLOS PATHOG 2016;12 (8):e1005774 [PubMed]
  • van den Kerkhof TLGM, de Taeye SW, Boeser-Nunnink BD, Burton DR, Kootstra NA, Schuitemaker H, Sanders RW, van Gils MJ, HIV-1 escapes from N332-directed antibody neutralization in an elite neutralizer by envelope glycoprotein elongation and introduction of unusual disulfide bonds. RETROVIROLOGY 2016;13 (1):48 [PubMed]
  • van den Kerkhof TLGM, van Gils MJ, Boeser-Nunnink BD, Burger JA, Schuitemaker H, Sanders RW, Probability of N332 glycan occupancy on HIV-1 gp120 modulates sensitivity to broadly neutralizing antibodies. AIDS 2016;30 (14):2179-2184 [PubMed]

2014

  • van den Kerkhof TLGM, Euler Z, van Gils MJ, Boeser-Nunnink BD, Schuitemaker H, Sanders RW, Early development of broadly reactive HIV-1 neutralizing activity in elite neutralizers. AIDS 2014;28 (8):1237-1240 [PubMed]

2013

  • Euler Z, van Gils MJ, Boeser-Nunnink BD, Schuitemaker H, van Manen D, Genome-wide association study on the development of cross-reactive neutralizing antibodies in HIV-1 infected individuals. PLOS ONE 2013;8 (1):e54684 [PubMed]
  • van den Kerkhof TLGM, Feenstra KA, Euler Z, van Gils MJ, Rijsdijk LWE, Boeser-Nunnink BD, Heringa J, Schuitemaker H, Sanders RW, HIV-1 envelope glycoprotein signatures that correlate with the development of cross-reactive neutralizing activity. RETROVIROLOGY 2013;10 (1):102 [PubMed]

2012

  • Bol SM, Booiman T, van Manen D, Bunnik EM, van Sighem AI, Sieberer M, Boeser-Nunnink B, de Wolf F, Schuitemaker H, Portegies P, Kootstra NA, van 't Wout AB, Single Nucleotide Polymorphism in Gene Encoding Transcription Factor Prep1 Is Associated with HIV-1-Associated Dementia. PLOS ONE 2012;7 (2):e30990 [PubMed]
  • Edo-Matas D, Rachinger A, Setiawan LC, Boeser-Nunnink BD, van 't Wout AB, Lemey P, Schuitemaker H, The evolution of human immunodeficiency virus type-1 (HIV-1) envelope molecular properties and coreceptor use at all stages of infection in an HIV-1 donor-recipient pair. VIROLOGY 2012;422 (1):70-80 [PubMed]

2011

  • Euler Z, Bunnik EM, Burger JA, Boeser-Nunnink BDM, Grijsen ML, Prins JM, Schuitemaker H, Activity of broadly neutralizing antibodies, including PG9, PG16, and VRC01, against recently transmitted subtype B HIV-1 variants from early and late in the epidemic. J VIROL 2011;85 (14):7236-7245 [PubMed]
  • Schellens IMM, Navis M, van Deutekom HWM, Boeser-Nunnink B, Berkhout B, Kootstra N, Miedema F, Keşmir C, Schuitemaker H, van Baarle D, Borghans JAM, Loss of HIV-1-derived cytotoxic T lymphocyte epitopes restricted by protective HLA-B alleles during the HIV-1 epidemic. AIDS 2011;25 (14):1691-1700 [PubMed]
  • van Gils MJ, Bunnik EM, Boeser-Nunnink BD, Burger JA, Terlouw-Klein M, Verwer N, Schuitemaker H, Longer V1V2 region with increased number of potential N-linked glycosylation sites in the HIV-1 envelope glycoprotein protects against HIV-specific neutralizing antibodies. J VIROL 2011;85 (14):6986-6995 [PubMed]
  • van Manen D, Delaneau O, Kootstra NA, Boeser-Nunnink BD, Limou S, Bol SM, Burger JA, Zwinderman AH, Moerland PD, van 't Slot R, Zagury JF, van 't Wout AB, Schuitemaker H, Genome-wide association scan in HIV-1-infected individuals identifying variants influencing disease course. PLOS ONE 2011;6 (7):e22208 [PubMed]
  • van Manen D, Gras L, Boeser-Nunnink BD, van Sighem AI, Maurer I, Mangas Ruiz MM, Harskamp AM, Steingrover R, Prins JM, de Wolf F, van 't Wout AB, Schuitemaker H, Rising HIV-1 viral load set point at a population level coincides with a fading impact of host genetic factors on HIV-1 control. AIDS 2011;25 (18):2217-2226 [PubMed]

2010

  • Bunnik EM, Euler Z, Welkers MRA, Boeser-Nunnink BDM, Grijsen ML, Prins JM, Schuitemaker H, Adaptation of HIV-1 envelope gp120 to humoral immunity at a population level. NAT MED 2010;16 (9):995-997 [PubMed]
  • Edo-Matas D, van Gils MJ, Bowles EJ, Navis M, Rachinger A, Boeser-Nunnink B, Stewart-Jones GB, Kootstra NA, Wout ABvt, Schuitemaker H, Genetic composition of replication competent clonal HIV-1 variants isolated from peripheral blood mononuclear cells (PBMC), HIV-1 proviral DNA from PBMC and HIV-1 RNA in serum in the course of HIV-1 infection. VIROLOGY 2010;405 (2):492-504 [PubMed]
  • van Manen D, Kootstra NA, Boeser-Nunnink B, Handulle MAM, van 't Wout AB, Schuitemaker H, Association of HLA-C and HCP5 gene regions with the clinical course of HIV-1 infection (vol 23, pg 19, 2009). AIDS 2010;24 (6):939

2009

  • van Manen D, Kootstra NA, Boeser-Nunnink B, Handulle MA, Vanʼt Wout AB, Schuitemaker H, Association of HLA-C and HCP5 gene regions with the clinical course of HIV-1 infection. AIDS 2009;23 (1):19-28 [PubMed]

2007

  • Bunnik EM, Quakkelaar ED, van Nuenen AC, Boeser-Nunnink B, Schuitemaker H, Increased neutralization sensitivity of recently emerged CXCR4-using human immunodeficiency virus type 1 strains compared to coexisting CCR5-using variants from the same patient. J VIROL 2007;81 (2):525-531 [PubMed]
  • Quakkelaar ED, Beaumont T, van Nuenen AC, van Alphen FPJ, Boeser-Nunnink BDM, van 't Wout AB, Schuitemaker H, T cell line passage can select for pre-existing neutralization-sensitive variants from the quasispecies of primary human immunodeficiency virus type-1 isolates. VIROLOGY 2007;359 (1):92-104 [PubMed]
  • Quakkelaar ED, Bunnik EM, van Alphen FPJ, Boeser-Nunnink BDM, van Nuenen AC, Schuitemaker H, Escape of human immunodeficiency virus type 1 from broadly neutralizing antibodies is not associated with a reduction of viral replicative capacity in vitro. VIROLOGY 2007;363 (2):447-453 [PubMed]
  • Quakkelaar ED, van Alphen FPJ, Boeser-Nunnink BDM, van Nuenen AC, Pantophlet R, Schuitemaker H, Susceptibility of recently transmitted subtype B human immunodeficiency virus type 1 variants to broadly neutralizing antibodies. J VIROL 2007;81 (16):8533-8542 [PubMed]

2005

  • van der Bij AK, Kloosterboer N, Prins M, Boeser-Nunnink B, Geskus RB, Lange JMA, Coutinho RA, Schuitemaker H, GB virus C coinfection and HIV-1 disease progression: The Amsterdam Cohort Study. J INFECT DIS 2005;191 (5):678-685 [PubMed]
  • van der Bij AK, Kloosterboer N, Prins M, Boeser-Nunnink B, Geskus RB, Lange JMA, Coutinho RA, Schuitemaker H, GB virus C infection and survival in the Amsterdam Cohort study - Reply to George and to Stapleton et al. J INFECT DIS 2005;191 (12):2158-2160

2004

  • Stalmeijer EHB, van Rij RP, Boeser-Nunnink B, Visser JA, Naarding MA, Schols D, Schuitemaker H, In vivo evolution of X4 human immunodeficiency virus type 1 variants in the natural course of infection coincides with decreasing sensitivity to CXCR4 antagonists. J VIROL 2004;78 (6):2722-2728 [PubMed]

2003

  • Koning FA, Kwa D, Boeser-Nunnink B, Dekker J, Vingerhoed J, Hiemstra H, Schuitemaker H, Decreasing sensitivity to RANTES (regulated on activation, normally T cell-expressed and -secreted) neutralization of CC chemokine receptor 5-using, non-syncytium-inducing virus variants in the course of human immunodeficiency virus type 1 infection. J INFECT DIS 2003;188 (6):864-872 [PubMed]
  • Kwa D, Boeser-Nunnink B, Schuitemaker H, Lack of evidence for an association between a polymorphism in CX3CR1 and the clinical course of HIV infection or virus phenotype evolution. AIDS 2003;17 (5):759-761 [PubMed]
  • Kwa D, van Rij RP, Boeser-Nunnink B, Vingerhoed J, Schuitemaker H, Association between an interleukin-4 promoter polymorphism and the acquisition of CXCR4 using HIV-1 variants. AIDS 2003;17 (7):981-985 [PubMed]
  • Kwa D, Vingerhoed J, Boeser B, Schuitemaker H, Increased in vitro cytopathicity of CC chemokine receptor 5-restricted human immunodeficiency virus type 1 primary isolates correlates with a progressive clinical course of infection. J INFECT DIS 2003;187 (9):1397-1403 [PubMed]

2001

  • Kwa D, Vingerhoed J, Boeser-Nunnink B, Broersen S, Schuitemaker H, Cytopathic effects of non-syncytium-inducing and syncytium-inducing human immunodeficiency virus type 1 variants on different CD4(+)-T-cell subsets are determined only by coreceptor expression. J VIROL 2001;75 (21):10455-10459 [PubMed]

1997

  • Bruisten SM, Oudshoorn P, van Swieten P, Boeser-Nunnink B, van Aarle P, Tondreau SP, Cuypers HT, Stability of HIV-1 RNA in blood during specimen handling and storage prior to amplification by NASBA-QT. J VIROL METHODS 1997;67 (2):199-207 [PubMed]

1994

  • Bresters D, Schipper ME, Reesink HW, Boeser-Nunnink BD, Cuypers HT, The duration of fixation influences the yield of HCV cDNA-PCR products from formalin-fixed, paraffin-embedded liver tissue. J VIROL METHODS 1994;48 (2-3):267-272 [PubMed]

1992

  • Bresters D, Cuypers HT, Reesink HW, Chamuleau RA, Schipper ME, Boeser-Nunnink BD, Lelie PN, Jansen PL, Detection of hepatitis C viral RNA sequences in fresh and paraffin-embedded liver biopsy specimens of non-A, non-B hepatitis patients. J HEPATOL 1992;15 (3):391-395 [PubMed]
  • Schuuring E, Verhoeven E, van Tinteren H, Peterse JL, Nunnink B, Thunnissen FB, Devilee P, Cornelisse CJ, van de Vijver MJ, Mooi WJ, Amplification of genes within the chromosome 11q13 region is indicative of poor prognosis in patients with operable breast cancer. CANCER RES 1992;52 (19):5229-5234 [PubMed]