Prof. dr. S. Florquin publications

foto

Publications Prof. dr. S. Florquin

Position
Professor
Main activities
Patient care, Research
Specialisation
Pathologist
Focus of research

Immunopathology of renal transplantation.

The role of innate immunity in renal damage and repair. 

2018

  • Bouatou Y, Kers J, Chevalier-Florquin MSN, Claessen N, Nguyen TQ, Damman J, Proença H, Roelofs JJTH, Florquin S, Diagnostic accuracy of immunofluorescence versus immunoperoxidase staining to distinguish immune complex-mediated glomerulonephritis and C3 dominant glomerulopathy. HISTOPATHOLOGY 2018;72 (4):601-608 [PubMed]
  • Bouatou Y, Stokman G, Claessen N, Roelofs JJTH, Bemelman F, Kers J, Florquin S, Aryl hydrocarbon receptor expression by macrophages and lymphocytes within infiltrates in BK polyomavirus associated nephropathy. TRANSPL IMMUNOL 2018;47:18-21 [PubMed]
  • Eymael J, Sharma S, Loeven MA, Wetzels JF, Mooren F, Florquin S, Deegens JK, Willemsen BK, Sharma V, van Kuppevelt TH, Bakker MA, Ostendorf T, Moeller MJ, Dijkman HB, Smeets B, van der Vlag J, CD44 is required for the pathogenesis of experimental crescentic glomerulonephritis and collapsing focal segmental glomerulosclerosis. KIDNEY INT 2018;93 (3):626-642 [PubMed]
  • Falix FA, Oosterveld MJS, Florquin S, Groothoff JW, Bouts AHM, Diagnostic dilemmas in a girl with acute glomerulonephritis: Answers. PEDIATR NEPHROL 2018;33 (1):65-69 [PubMed]
  • Falix FA, Oosterveld MJS, Florquin S, Groothoff JW, Bouts AHM, Diagnostic dilemmas in a girl with acute glomerulonephritis: Questions. PEDIATR NEPHROL 2018;33 (1):63-64 [PubMed]
  • Jansen MPB. The role of platelets in acute kidney injury. S.l.: s.n.; 2018. 203p. ISBN 789463801454 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Florquin S; copromotor(s): Roelofs JJTH)
  • Jansen MPB, Florquin S, Roelofs JJTH, The role of platelets in acute kidney injury. NAT REV NEPHROL 2018;14 (7):457-471 [PubMed]
  • Jansen MPB, Pulskens WP, Butter LM, Florquin S, Juffermans NP, Roelofs JJTH, Leemans JC, MITOCHONDRIAL DNA IS RELEASED IN URINE OF SIRS PATIENTS WITH ACUTE KIDNEY INJURY AND CORRELATES WITH SEVERITY OF RENAL DYSFUNCTION. SHOCK 2018;49 (3):301-310 [PubMed]
  • Jansen MPB, Pulskens WPC, Uil M, Claessen N, Nieuwenhuizen G, Standaar D, Hau CM, Nieuwland R, Florquin S, Bemelman FJ, Leemans JC, Roelofs JJTH, Urinary mitochondrial deoxyribonucleic acid associates with delayed graft function following renal transplantation. NEPHROL DIAL TRANSPL 2018;ahead of print [PubMed]
  • Kors L, Rampanelli E, Stokman G, Butter LM, Held NM, Claessen N, Larsen PWB, Verheij J, Zuurbier CJ, Liebisch G, Schmitz G, Girardin SE, Florquin S, Houtkooper RH, Leemans JC, Deletion of NLRX1 increases fatty acid metabolism and prevents diet-induced hepatic steatosis and metabolic syndrome. BBA-MOL BASIS DIS 2018;1864 (5 Part A):1883-1895 [PubMed]
  • Multon S, Pesesse L, Weatherspoon A, Florquin S, van de Poel JF, Martin P, Vincke G, Hoyoux R, Marée R, Verpoorten D, Bonnet P, Quatresooz P, Defaweux V, Un « Massive Open Online Course » (MOOC) sur des travaux pratiques en histologie : un objectif, un outil, un public varié ! Retour sur une première expérience. ANN PATHOL 2018;38 (2):76-84 [PubMed]
  • Rampanelli E, Ochodnicky P, Vissers JP, Butter LM, Claessen N, Calcagni A, Kors L, Gethings LA, Bakker SJ, de Borst MH, Navis GJ, Liebisch G, Speijer D, van den Bergh Weerman MA, Jung B, Aten J, Steenbergen E, Schmitz G, Ballabio A, Florquin S, Aerts JM, Leemans JC, Excessive dietary lipid intake provokes an acquired form of lysosomal lipid storage disease in the kidney. J PATHOL 2018;246 (4):470-484 [PubMed]
  • Stroo I, Emal D, Butter LM, Teske GJ, Claessen N, Dessing MC, Girardin SE, Florquin S, Leemans JC, No difference in renal injury and fibrosis between wild-type and NOD1/NOD2 double knockout mice with chronic kidney disease induced by ureteral obstruction. BMC NEPHROL 2018;19 (1):78 [PubMed]
  • Tammaro A. Immune-mediated mechanisms of (mal)adaptive renal tissue repair. S.l.: s.n.; 2018. 187p. ISBN 9789463750622 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Florquin S; copromotor(s): Dessing MC, Leemans JC)
  • Tammaro A, Florquin S, Brok M, Claessen N, Butter LM, Teske GJD, de Boer OJ, Vogl T, Leemans JC, Dessing MC, S100A8/A9 promotes parenchymal damage and renal fibrosis in obstructive nephropathy. CLIN EXP IMMUNOL 2018;193 (3):361-375 [PubMed]
  • Uil M, Scantlebery AML, Butter LM, Larsen PWB, de Boer OJ, Leemans JC, Florquin S, Roelofs JJTH, Combining streptozotocin and unilateral nephrectomy is an effective method for inducing experimental diabetic nephropathy in the 'resistant' C57Bl/6J mouse strain. SCI REP-UK 2018;8 (1):5542 [PubMed]
  • van Lieshout MHP, de Vos AF, Dessing MC, de Porto APNA, de Boer OJ, de Beer R, Terpstra S, Florquin S, van't Veer C, van der Poll T, ASC and NLRP3 impair host defense during lethal pneumonia caused by serotype 3 Streptococcus pneumoniae in mice. EUR J IMMUNOL 2018;48 (1):66-79 [PubMed]
  • van Sandwijk MS, de Vries APJ, Bakker SJL, ten Berge IJM, Berger SP, Bouatou YR, de Fijter JW, Florquin S, Homan van der Heide JJ, Idu MM, Krikke C, van der Pant KAMI, Reinders ME, Ringers J, van der Weerd NC, Bemelman FJ, Sanders JSS, Early Steroid Withdrawal Compared With Standard Immunosuppression in Kidney Transplantation - Interim Analysis of the Amsterdam-Leiden-Groningen Randomized Controlled Trial. TRANSPLANT DIRECT 2018;4 (6):e354 [PubMed]
  • Waasdorp M. Protease-activated receptors in diabetic nephropathy and renal fibrosis. S.l.: s.n.; 2018. 170p. ISBN 9789463800709 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): van der Poll T, Florquin S; copromotor(s): Spek CA, Duitman JW)
  • Waasdorp M, de Rooij DM, Florquin S, Duitman J, Spek CA, Protease-activated receptor-1 contributes to renal injury and interstitial fibrosis during chronic obstructive nephropathy. J CELL MOL MED 2018;ahead of print [PubMed]
  • Waasdorp M, Duitman J, Florquin S, Spek CA, Vorapaxar treatment reduces mesangial expansion in streptozotocin-induced diabetic nephropathy in mice. ONCOTARGET 2018;9 (31):21655-21662 [PubMed]
  • Waasdorp M, Duitman JW, Florquin S, Spek CA, Erratum: Protease activated receptor 2 in diabetic nephropathy: a double edged sword. AM J TRANSL RES 2018;10 (7):2220 [PubMed]

2017

  • Anas AA, Claushuis TAM, Mohan RA, Christoffels VM, Aidinis V, Florquin S, van't Veer C, Hou B, de Vos AF, van der Poll T, Epithelial Myeloid-Differentiation Factor 88 Is Dispensable during Klebsiella Pneumonia. AM J RESP CELL MOL 2017;56 (5):648-656 [PubMed]
  • Bellur SS, Lepeytre F, Vorobyeva O, Troyanov S, Cook HT, Roberts ISD [Contributors: Alpers CE, Amore A, Barratt J, Berthoux F, Bonsib S, Bruijn JA, Cattran DC, Coppo R, D'Agati V, D'Amico G, Emancipator S, Emma F, Feehally J, Ferrario F, Fervenza FC, Florquin S, Fogo A, Geddes CC, Groene HJ, Haas M, Herzenberg AM, Hill PA, Hogg RJ, Hsu SI, Jennette JC, Joh K, Julian BA, Kawamura T, Lai FM, Li LS, Li PKT, Liu ZH, Mackinnon B, Mezzano S, Schena FP, Tomino Y, Walker PD, Wang H, Weening JJ, Yoshikawa N, Zhang H]] , Evidence from the Oxford Classification cohort supports the clinical value of subclassification of focal segmental glomerulosclerosis in IgA nephropathy. KIDNEY INT 2017;91 (1):235-243 [PubMed]
  • Bemelman FJ, de Fijter JW, Kers J, Meyer C, Peters-Sengers H, de Maar EF, van der Pant KAMI, de Vries APJ, Sanders JS, Zwinderman A, Idu MM, Berger S, Reinders MEJ, Krikke C, Bajema IM, van Dijk MC, ten Berge IJM, Ringers J, Lardy J, Roelen D, Moes DJ, Florquin S, Homan van der Heide JJ, Early Conversion to Prednisolone/Everolimus as an Alternative Weaning Regimen Associates With Beneficial Renal Transplant Histology and Function: The Randomized-Controlled MECANO Trial. AM J TRANSPLANT 2017;17 (4):1020-1030 [PubMed]
  • Emal D, Rampanelli E, Stroo I, Butter LM, Teske GJ, Claessen N, Stokman G, Florquin S, Leemans JC, Dessing MC, Depletion of Gut Microbiota Protects against Renal Ischemia-Reperfusion Injury. J AM SOC NEPHROL 2017;28 (5):1450-1461 [PubMed]
  • Falix FA, Bennebroek CAM, van der Zwaag B, Lapid-Gortzak R, Florquin S, Oosterveld MJS, A novel mutation of laminin beta 2 (LAMB2) in two siblings with renal failure. EUR J PEDIATR 2017;176 (4):515-519 [PubMed]
  • García-Laorden MI, Stroo I, Terpstra S, Florquin S, Medema JP, van T Veer C, de Vos AF, van der Poll T, Escherichia coli Peritonitis and Sepsis. MEDIAT INFLAMM 2017;2017:4137563 [PubMed]
  • Jansen MPB, Emal D, Teske GJD, Dessing MC, Florquin S, Roelofs JJTH, Release of extracellular DNA influences renal ischemia reperfusion injury by platelet activation and formation of neutrophil extracellular traps. KIDNEY INT 2017;91 (2):352-364 [PubMed]
  • Maicas N, van der Vlag J, Bublitz J, Florquin S, Bakker-van Bebber M, Dinarello CA, Verweij V, Masereeuw R, Joosten LA, Hilbrands LB, Human Alpha-1-Antitrypsin (hAAT) therapy reduces renal dysfunction and acute tubular necrosis in a murine model of bilateral kidney ischemia-reperfusion injury. PLOS ONE 2017;12 (2):e0168981 [PubMed]
  • Mesarosova L, Ochodnicky P, Leemans JC, Florquin S, Krenek P, Klimas J, High glucose induces HGF-independent activation of Met receptor in human renal tubular epithelium. J RECEPT SIG TRANSD 2017;37 (6):535-542 [PubMed]
  • Ochodnicky P, Lattenist L, Ahdi M, Kers J, Uil M, Claessen N, Leemans JC, Florquin S, Meijers JCM, Gerdes VEA, Roelofs JJTH, Increased Circulating and Urinary Levels of Soluble TAM Receptors in Diabetic Nephropathy. AM J PATHOL 2017;187 (9):1971-1983 [PubMed]
  • Rampanelli E, Orsó E, Ochodnicky P, Liebisch G, Bakker PJ, Claessen N, Butter LM, van den Bergh Weerman MA, Florquin S, Schmitz G, Leemans JC, Metabolic injury-induced NLRP3 inflammasome activation dampens phospholipid degradation. SCI REP-UK 2017;7 (1):2861 [PubMed]
  • Riool M, Dirks AJ, Jaspers V, de Boer L, Loontjens TJ, van der Loos CM, Florquin S, Apachitei I, Rijk LN, Keul HA, Zaat SA, A chlorhexidine-releasing epoxy-based coating on titanium implants prevents Staphylococcus aureus experimental biomaterial-associated infection. EUR CELLS MATER 2017;33:143-157 [PubMed]
  • Stokman G, Kors L, Bakker PJ, Rampanelli E, Claessen N, Teske GJD, Butter L, van Andel H, van den Bergh Weerman MA, Larsen PWB, Dessing MC, Zuurbier CJ, Girardin SE, Florquin S, Leemans JC, NLRX1 dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity. J EXP MED 2017;214 (8):2405-2420 [PubMed]
  • Tammaro A, Derive M, Gibot S, Leemans JC, Florquin S, Dessing MC, TREM-1 and its potential ligands in non-infectious diseases: from biology to clinical perspectives. PHARMACOL THERAPEUT 2017;177:81-95 [PubMed]
  • Tammaro A, Kers J, Emal D, Stroo I, Teske GJD, Butter LM, Claessen N, Damman J, Derive M, Navis GJ, Florquin S, Leemans JC, Dessing MC, Effect of TREM-1 blockade and single nucleotide variants in experimental renal injury and kidney transplantation (vol 6, 38275, 2016). SCI REP-UK 2017;7:44163 [PubMed]
  • van den Hoogen MWF, Steenbergen EJ, Baas MC, Florquin S, Hilbrands LB, Absence of Intragraft B Cells in Rejection Biopsies After Rituximab Induction Therapy: Consequences for Clinical Outcome. TRANSPLANT DIRECT 2017;3 (4):e143 [PubMed]
  • Waasdorp M, Duitman J, Florquin S, Spek AC, Protease activated receptor 2 in diabetic nephropathy: a double edged sword. AM J TRANSL RES 2017;9 (10):4512-4520 [PubMed]

2016

  • Achouiti A, de Vos AF, van 't Veer C, Florquin S, Tanck MW, Nawroth PP, Bierhaus A, van der Poll T, van Zoelen MAD, Receptor for Advanced Glycation End Products (RAGE) Serves a Protective Role during Klebsiella pneumoniae - Induced Pneumonia. PLOS ONE 2016;11 (1):e0141000 [PubMed]
  • Anas AA, de Vos AF, Hoogendijk AJ, van Lieshout MHP, van Heijst JWJ, Florquin S, Li Z, van 't Veer C, van der Poll T, Endoplasmic reticulum chaperone gp96 in macrophages is essential for protective immunity during Gram-negative pneumonia. J PATHOL 2016;238 (1):74-84 [PubMed]
  • Anas AA, van Lieshout MHP, Claushuis TAM, de Vos AF, Florquin S, de Boer OJ, Hou B, van't Veer C, van der Poll T, Lung epithelial MyD88 drives early pulmonary clearance of Pseudomonas aeruginosa by a flagellin dependent mechanism. AM J PHYSIOL-LUNG C 2016;311 (2):L219-L228 [PubMed]
  • Barbour SJ, Espino-Hernandez G, Reich HN, Coppo R, Roberts ISD, Feehally J, Herzenberg AM, Cattran DC [Contributors: Bavbek N, Cook T, Troyanov S, Alpers C, Amore A, Barratt J, Berthoux F, Bonsib S, Bruijn J, D'Agati V, D'Amico G, Emancipator S, Emmal F, Ferrario F, Fervenza F, Florquin S, Fogo A, Geddes C, Groene H, Haas M, Hill P, Hogg R, Hsu S, Hunley T, Hladunewich M, Jennette C, Joh K, Julian B, Kawamura T, Lai F, Leung C, Li L, Li P, Liu Z, Massat A, MacKinnon B, Mezzano S, Schena F, Tomino Y, Walker P, Wang H, Weening J, Yoshikawa N, Zhang H, Coppo R, Cattran DC, Cook HT, Feehally J, Roberts I, Tesar V, Maixnerova D, Lundberg S, Gesualdo L, Emma F, Fuiano L, Beltrame G, Rollino C, Camilla R, Peruzzi L, Praga M, Feriozzi S, Polci R, Segoloni G, Colla L, Pani A, Angioi A, Piras L, Cancarini G, Ravera S, Durlik M, Moggia E, Ballarin J, Di Giulio S, Pugliese F, Serriello I, Caliskan Y, Sever M, Kilicaslan I, Locatelli F, del Vecchio L, Wetzels JFM, Peters H, Berg U, Carvalho F, da Costa Ferreira AC, Maggio M, Wiecek A, Ots-Rosenberg M, Magistroni R, Topaloglu R, Bilginer Y, D'amico M, Stangou M, Giacchino F, Goumenos D, Kalliakmani P, Gerolymos M, Galesic K, Siamopoulos K, Balafa O, Galliani M, Stratta P, Quaglia M, Bergia R, Cravero R, Salvadori M, Cirami L, Fellstrom B, Kloster Smerud H, Stellato T, Egido J, Martin C, Floege J, Eitner F, Lupo A, Bernich P, Mene P, Morosetti M, van Kooten C, Rabelink T, Reinders MEJ, Boria Grinyo JM, Cusinato S, Benozzi L, Savoldi S, Licata C, Mizerska-Wasiak M, Martina G, Messuerotti A, Dal Canton A, Esposito C, Migotto C, Triolo G, Mariano F, Pozzi C, Boero R, Bellur S, Mazzucco G, Giannakakis C, Honsova E, Sundelin B, Di Palma AM, Gutierrez E, Asunis AM, Tardanico R, Perkowska-Ptasinska A, Arce Terroba J, Fortunato M, Pantzaki A, Ozluk Y, Steenbergen E, Soderberg M, Riispere Z, Furci L, Orhan D, Kipgen D, Casartelli D, Galesic Ljubanovic D, Gakiopoulou H, Bertoni E, Cannata Ortiz P, Karkoszka H, Groene HJ, Stoppacciaro A, Bajema I, Fulladosa Oliveras X, Maldyk J, Ioachim E]] , The MEST score provides earlier risk prediction in lgA nephropathy. KIDNEY INT 2016;89 (1):167-175 [PubMed]
  • Bueters RRG, Jeronimus-Klaasen A, Maicas N, Florquin S, van den Heuvel LP, Schreuder MF, The Effects of Early Postnatal Diuretics Treatment on Kidney Development and Long-Term Kidney Function in Wistar Rats. NEPHRON 2016;132 (2):110-118 [PubMed]
  • Dessing MC, Kers J, Damman J, Navis GJ, Florquin S, Leemans JC, Donor and recipient genetic variants in NLRP3 associate with early acute rejection following kidney transplantation. SCI REP-UK 2016;6:36315 [PubMed]
  • García-Laorden MI, Stroo I, Blok DC, Florquin S, Medema JP, de Vos AF, van der Poll T, Granzymes A and B Regulate the Local Inflammatory Response during Klebsiella pneumoniae Pneumonia. J INNATE IMMUN 2016;8 (3):258-268 [PubMed]
  • Hoelbeek J, Duivenvoorden R, de Boer OJ, Claessen N, van den Bergh Weerman MA, Roelofs JJTH, Kers J, ten Berge IJM, Florquin S, Unique Renal Manifestation of Type I Cryoglobulinemia, With Massive Crystalloid Deposits in Glomerular Histiocytes, Podocytes, and Endothelial Cells. AM J CLIN PATHOL 2016;145 (2):282-285 [PubMed]
  • Kers J. Determinants of acute and chronic renal allograft injury. S.l.: s.n.; 2016. 383p. ISBN 978-94-6299-351-8 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Florquin S, ten Berge RJM; copromotor(s): Bemelman FJ, Dessing MC)
  • Lattenist L. The Protein C system in renal disease. S.l.: s.n.; 2016. 213p. ISBN 978-94-91602-62-7 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Florquin S; copromotor(s): Roelofs JJTH)
  • Lattenist L, Jansen MPB, Teske G, Claessen N, Meijers JCM, Rezaie AR, Esmon CT, Florquin S, Roelofs JJTH, Activated protein C protects against renal ischaemia/reperfusion injury, independent of its anticoagulant properties. THROMB HAEMOSTASIS 2016;116 (1):124-133 [PubMed]
  • Lattenist L, Ochodnický P, Ahdi M, Claessen N, Leemans JC, Satchell SC, Florquin S, Gerdes VE, Roelofs JJTH, Renal endothelial protein C receptor expression and shedding during diabetic nephropathy. J THROMB HAEMOST 2016;14 (6):1171-1182 [PubMed]
  • Sonneveld R, Hoenderop JGJ, Stavenuiter AWD, Ferrantelli E, Baltissen MPA, Dijkman HB, Florquin S, Rops AL, Wetzels JFM, Berden JHM, van der Vlag J, Nijenhuis T, 1,25-Vitamin D3 Deficiency Induces Albuminuria. AM J PATHOL 2016;186 (4):794-804 [PubMed]
  • Stokman G, Kers J, Yapici Ü, Hoelbeek JJ, Claessen N, de Boer OJ, Netea MG, Hilbrands L, Bemelman FJ, ten Berge IJM, Florquin S, Predominant Tubular Interleukin-18 Expression in Polyomavirus-Associated Nephropathy. TRANSPLANTATION 2016;100 (10):e88-e95 [PubMed]
  • Tammaro A, Kers J, Emal D, Stroo I, Teske GJD, Butter LM, Claessen N, Damman J, Derive M, Navis G, Florquin S, Leemans JC, Dessing MC, Effect of TREM-1 blockade and single nucleotide variants in experimental renal injury and kidney transplantation. SCI REP-UK 2016;6:38275 [PubMed]
  • van der Meer AJ, Achouiti A, van der Ende A, Soussan AA, Florquin S, de Vos A, Zeerleder SS, van der Poll T, Toll-like receptor 9 enhances bacterial clearance and limits lung consolidation in murine pneumonia caused by methicillin resistant Staphylococcus aureus. MOL MED 2016;22:292-299 [PubMed]
  • Waasdorp M, Duitman J, Florquin S, Spek CA, Protease-activated receptor-1 deficiency protects against streptozotocin-induced diabetic nephropathy in mice. SCI REP-UK 2016;6:33030 [PubMed]
  • Yapici Ü, Kers J, Slavujevic-Letic I, Stokman G, Roelofs JJTH, van Aalderen MC, Groothoff JW, de Boer OJ, van der Pant KAMI, Claessen N, Hilbrands LB, Bemelman FJ, ten Berge IJM, Florquin S, Intragraft Blood Dendritic Cell Antigen-1-Positive Myeloid Dendritic Cells Increase during BK Polyomavirus-Associated Nephropathy. J AM SOC NEPHROL 2016;27 (8):2502-2510 [PubMed]

2015

  • Achouiti A, Vogl T, van der Meer AJ, Stroo I, Florquin S, de Boer OJ, Roth J, Zeerleder S, van 't Veer C, de Vos AF, van der Poll T, Myeloid-related protein-14 deficiency promotes inflammation in staphylococcal pneumonia. EUR RESPIR J 2015;46 (2):464-473 [PubMed]
  • Bakker PJ. Tissue-specific roles of the pattern recognition receptors NLRP3, NLRX1 and TLR9 in sterile inflammatory kidney disease. S.l.: s.n.; 2015. 160p. [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Florquin S; copromotor(s): Leemans JC)
  • Bakker PJ, Scantlebery AM, Butter LM, Claessen N, Teske GJD, van der Poll T, Florquin S, Leemans JC, TLR9 Mediates Remote Liver Injury following Severe Renal Ischemia Reperfusion. PLOS ONE 2015;10 (9):e0137511 [PubMed]
  • Bueters RRG, Klaasen A, Maicas N, Florquin S, van den Heuvel LP, Schreuder MF, Impact of Early Postnatal NSAID Treatment on Nephrogenesis in Wistar Rats. BIRTH DEFECTS RES B 2015;104 (5):218-226 [PubMed]
  • Dessing MC, Kers J, Damman J, Leuvenink HGD, van Goor H, Hillebrands JL, Hepkema BG, Snieder H, van den Born J, de Borst MH, Bakker SJL, Navis GJ, Ploeg RJ, Florquin S, Seelen M, Leemans JC, Toll-Like Receptor Family Polymorphisms Are Associated with Primary Renal Diseases but Not with Renal Outcomes Following Kidney Transplantation. PLOS ONE 2015;10 (10):e0139769 [PubMed]
  • Dessing MC, Tammaro A, Pulskens WP, Teske GJ, Butter LM, Claessen N, van Eijk M, van der Poll T, Vogl T, Roth J, Florquin S, Leemans JC, The calcium-binding protein complex S100A8/A9 has a crucial role in controlling macrophage-mediated renal repair following ischemia/reperfusion. KIDNEY INT 2015;87 (1):85-94 [PubMed]
  • de Vos AF, Dessing MC, Lammers AJJ, de Porto APNA, Florquin S, de Boer OJ, de Beer R, Terpstra S, Bootsma HJ, Hermans PW, van 't Veer C, van der Poll T, The polysaccharide capsule of Streptococcus pneumonia partially impedes MyD88-mediated immunity during pneumonia in mice. PLOS ONE 2015;10 (2):e0118181 [PubMed]
  • Hommes TJ, Dessing MC, Veer Cvt, Florquin S, Colonna M, de Vos AF, van der Poll T, Role of Triggering Receptor Expressed on Myeloid Cells-1/3 in Klebsiella-Derived Pneumosepsis. AM J RESP CELL MOL 2015;53 (5):647-655 [PubMed]
  • Hommes TJ, van Lieshout MH, van 't Veer C, Florquin S, Bootsma HJ, Hermans PW, de Vos AF, van der Poll T, Role of Nucleotide-Binding Oligomerization Domain-Containing (NOD) 2 in Host Defense during Pneumococcal Pneumonia. PLOS ONE 2015;10 (12):e0145138 [PubMed]
  • Kers J, Florquin S, Generation of Alloreactive-Anergized Tr1 Cells From Patients on Dialysis for the Induction of Renal Transplant Tolerance: Are We There Yet?. TRANSPLANTATION 2015;99 (8):1551-1552 [PubMed]
  • Lattenist L, Teske G, Claessen N, Florquin S, Conway EM, Roelofs JJTH, The lectin like domain of thrombomodulin is involved in the defence against pyelonephritis. THROMB RES 2015;136 (6):1325-1331 [PubMed]
  • Oosterveld MJS, Garrelfs MR, Hoppe B, Florquin S, Roelofs JJTH, van den Heuvel LP, Amann K, Davin JC, Bouts AHM, Schriemer PJ, Groothoff JW, Eculizumab in Pediatric Dense Deposit Disease. CLIN J AM SOC NEPHRO 2015;10 (10):1773-1782 [PubMed]
  • Scicluna BP, van Lieshout MH, Blok DC, Florquin S, van der Poll T, Modular Transcriptional Networks of the Host Pulmonary Response during Early and Late Pneumococcal Pneumonia. MOL MED 2015;21 (1):430-441 [PubMed]
  • Sentís A, Kers J, Yapici U, Claessen N, Roelofs JJTH, Bemelman FJ, ten Berge IJM, Florquin S, The prognostic significance of glomerular infiltrating leukocytes during acute renal allograft rejection. TRANSPL IMMUNOL 2015;33 (3):168-175 [PubMed]
  • Smid BE, Hollak CEM, Poorthuis BJHM, van den Bergh Weerman MA, Florquin S, Kok WEM, Lekanne Deprez RH, Timmermans J, Linthorst GE, Diagnostic dilemmas in Fabry disease: a case series study on GLA mutations of unknown clinical significance. CLIN GENET 2015;88 (2):161-166 [PubMed]
  • Stroo I, Claessen N, Teske GJD, Butter LM, Florquin S, Leemans JC, Deficiency for the chemokine monocyte chemoattractant protein-1 aggravates tubular damage after renal ischemia/reperfusion injury. PLOS ONE 2015;10 (4):e0123203 [PubMed]
  • van den Hoogen MWF, Kamburova EG, Baas MC, Steenbergen EJ, Florquin S, M Koenen HJP, Joosten I, Hilbrands LB, Rituximab as Induction Therapy After Renal Transplantation: A Randomized, Double-Blind, Placebo-Controlled Study of Efficacy and Safety. AM J TRANSPLANT 2015;15 (2):407-416 [PubMed]
  • van der Tol L, Svarstad E, Ortiz A, Tøndel C, Oliveira JP, Vogt L, Waldek S, Hughes DA, Lachmann RH, Terryn W, Hollak CE, Florquin S, van den Bergh Weerman MA, Wanner C, West ML, Biegstraaten M, Linthorst GE, Chronic kidney disease and an uncertain diagnosis of Fabry disease: Approach to a correct diagnosis. MOL GENET METAB 2015;114 (2):242-247 [PubMed]
  • van Lieshout MHP, Florquin S, Vanʼt Veer C, de Vos AF, van der Poll T, TIR-Domain-Containing Adaptor-Inducing Interferon-β (TRIF) Mediates Antibacterial Defense during Gram-Negative Pneumonia by Inducing Interferon-x03B3. J INNATE IMMUN 2015;7 (6):637-646 [PubMed]

2014

  • Achouiti A, Vogl T, Endeman H, Mortensen BL, Laterre PF, Wittebole X, van Zoelen MAD, Zhang Y, Hoogerwerf JJ, Florquin S, Schultz MJ, Grutters JC, Biesma DH, Roth J, Skaar EP, van 't Veer C, de Vos AF, van der Poll T, Myeloid-related protein-8/14 facilitates bacterial growth during pneumococcal pneumonia. THORAX 2014;69 (11):1034-1042 [PubMed]
  • Bakker PJ, Butter LM, Claessen N, Teske GJD, Sutterwala FS, Florquin S, Leemans JC, A tissue-specific role for Nlrp3 in tubular epithelial repair after renal ischemia/reperfusion. AM J PATHOL 2014;184 (7):2013-2022 [PubMed]
  • Bakker PJ, Butter LM, Kors L, Teske GJD, Aten J, Sutterwala FS, Florquin S, Leemans JC, Nlrp3 is a key modulator of diet-induced nephropathy and renal cholesterol accumulation. KIDNEY INT 2014;85 (5):1112-1122 [PubMed]
  • Blok DC, van Lieshout MHP, Hoogendijk AJ, Florquin S, de Boer OJ, Garlanda C, Mantovani A, van't Veer C, de Vos AF, van der Poll T, Single immunoglobulin interleukin-1 receptor-related molecule impairs host defense during pneumonia and sepsis caused by Streptococcus pneumoniae. J INNATE IMMUN 2014;6 (4):542-552 [PubMed]
  • Duitman J, Borensztajn KS, Pulskens WPC, Leemans JC, Florquin S, Spek CA, CCAAT-enhancer binding protein delta (C/EBPδ) attenuates tubular injury and tubulointerstitial fibrogenesis during chronic obstructive nephropathy. LAB INVEST 2014;94 (1):89-97 [PubMed]
  • Duitman J, Ruela-de-Sousa RR, Shi K, de Boer OJ, Borensztajn KS, Florquin S, Peppelenbosch MP, Spek CA, Protease activated receptor-1 deficiency diminishes bleomycin-induced skin fibrosis. MOL MED 2014;20:410-416 [PubMed]
  • Duitman JW. Infectious diseases and fibrotic disorders: potential novel targets. s.l.: s.n.; 2014. 194p. ISBN 9789088918636 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Florquin S, van der Poll T; copromotor(s): Spek A, Peppelenbosch MP)
  • Hommes TJ, Hoogendijk AJ, Dessing MC, van't Veer C, Florquin S, Colonna M, de Vos AF, van der Poll T, Triggering receptor expressed on myeloid cells-1 (TREM-1) improves host defence in pneumococcal pneumonia. J PATHOL 2014;233 (4):357-367 [PubMed]
  • Hommes TJ, Hoogendijk AJ, Dessing MC, van't Veer C, Florquin S, de Vos AF, van der Poll T, DNAX-Activating Protein of 12 kDa Impairs Host Defense in Pneumococcal Pneumonia. CRIT CARE MED 2014;42 (12):E783-E790 [PubMed]
  • Leemans JC, Kors L, Anders HJ, Florquin S, Pattern recognition receptors and the inflammasome in kidney disease. NAT REV NEPHROL 2014;10 (7):398-414 [PubMed]
  • Oosterveld MJS, Florquin S, van den Bergh Weerman M, Vogt L, The zebra among horses: extensive abnormalities in a kidney biopsy without clinical signs of kidney disease. Fabry's disease. NETH J MED 2014;72 (6):331, 335-335 [PubMed]
  • Pulskens WP, Butter LM, Teske GJ, Claessen N, Dessing MC, Flavell RA, Sutterwala FS, Florquin S, Leemans JC, Nlrp3 prevents early renal interstitial edema and vascular permeability in unilateral ureteral obstruction. PLOS ONE 2014;9 (1):e85775 [PubMed]
  • Rampanelli E. CD44, TLR4, TREM-1/DAP12 in renal injury, inflammation and fibrosis. s.l.: s.n.; 2014. 191p. ISBN 9789461824349 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Florquin S; copromotor(s): Leemans JC)
  • Rampanelli E, Rouschop KMA, Claessen N, Teske GJD, Pals ST, Leemans JC, Florquin S, Opposite role of CD44-standard and CD44-variant-3 in tubular injury and development of renal fibrosis during chronic obstructive nephropathy. KIDNEY INT 2014;86 (3):558-569 [PubMed]
  • Smid BE, van der Tol L, Cecchi F, Elliott PM, Hughes DA, Linthorst GE, Timmermans J, Weidemann F, West ML, Biegstraaten M, Lekanne Deprez RH, Florquin S, Postema PG, Tomberli B, van der Wal AC, van den Bergh Weerman MA, Hollak CE, Uncertain diagnosis of Fabry disease: consensus recommendation on diagnosis in adults with left ventricular hypertrophy and genetic variants of unknown significance. INT J CARDIOL 2014;177 (2):400-408 [PubMed]
  • Stokman G, Qin Y, Booij TH, Ramaiahgari S, Lacombe M, Dolman MEM, van Dorenmalen KMA, Teske GJD, Florquin S, Schwede F, van de Water B, Kok RJ, Price LS, Epac-Rap signaling reduces oxidative stress in the tubular epithelium. J AM SOC NEPHROL 2014;25 (7):1474-1485 [PubMed]
  • ten Berge I, Heutinck K, Yapici U, Stokman G, Florquin S, van Kooten C, Garcia-Romo G, Ruben J, van de Vrie M, Hilbrands L, Michelo C, Joosten I, van den Heuvel H, Claas F, The interplay between antiviral immunity and allo-immune reactivity after renal transplantation Consortium between the Centres Amsterdam, Leiden and Nijmegen (ALLOVIR). TRANSPL IMMUNOL 2014;31 (4):191-194 [PubMed]
  • van Lieshout MHP, Anas AA, Florquin S, Hou B, van't Veer C, de Vos AF, van der Poll T, Hematopoietic but not endothelial cell MyD88 contributes to host defense during gram-negative pneumonia derived sepsis. PLOS PATHOG 2014;10 (9):e1004368 [PubMed]
  • van Lieshout MH, Scicluna BP, Florquin S, van der Poll T, NLRP3 and ASC differentially affect the lung transcriptome during pneumococcal pneumonia. AM J RESP CELL MOL 2014;50 (4):699-712 [PubMed]

2013

  • Achouiti A, de Vos AF, de Beer R, Florquin S, van 't Veer C, van der Poll T, Limited role of the receptor for advanced glycation end products during Streptococcus pneumoniae bacteremia. J INNATE IMMUN 2013;5 (6):603-612 [PubMed]
  • Achouiti A, van der Meer AJ, Florquin S, Yang H, Tracey KJ, van 't Veer C, de Vos AF, van der Poll T, High-mobility group box 1 and the receptor for advanced glycation end products contribute to lung injury during Staphylococcus aureus pneumonia. CRIT CARE 2013;17 (6):R296 [PubMed]
  • Baas MC, Gerdes VEA, ten Berge IJM, Heutinck KM, Florquin S, Meijers JCM, Bemelman FJ, Treatment with everolimus is associated with a procoagulant state. THROMB RES 2013;132 (2):307-311 [PubMed]
  • Baas MC, Kers J, Florquin S, de Fijter JW, van der Heide JJH, van den Bergh Weerman MA, ten Berge IJM, Bemelman FJ, Cyclosporine versus everolimus: effects on the glomerulus. CLIN TRANSPLANT 2013;27 (4):535-540 [PubMed]
  • Blok DC, de Vos AF, Florquin S, van der Poll T, Role of interleukin 1 receptor like 1 (ST2) in gram-negative and gram-positive sepsis in mice. SHOCK 2013;40 (4):290-296 [PubMed]
  • Blok DC, van der Sluijs KF, Florquin S, de Boer OJ, van 't Veer C, de Vos AF, van der Poll T, Limited anti-inflammatory role for interleukin-1 receptor like 1 (ST2) in the host response to murine postinfluenza pneumococcal pneumonia. PLOS ONE 2013;8 (3):e58191 [PubMed]
  • Duitman J, Schouten M, Groot AP, Borensztajn KS, Daalhuisen JB, Florquin S, van der Poll T, Spek CA, CCAAT/enhancer-binding protein delta facilitates bacterial dissemination during pneumococcal pneumonia in a platelet-activating factor receptor-dependent manner (vol 109, pg 9113, 2012). P NATL ACAD SCI USA 2013;110 (37):15163 [PubMed]
  • Duitman J, Teske GJD, Butter LM, Leemans JC, Florquin S, Spek CA, CCAAT/enhancer-binding protein delta (C/EBPδ) plays a minor role in renal host defense against uropathogenic Escherichia coli. TRANSPL INFECT DIS 2013;15 (3):E119-E121 [PubMed]
  • Kers J, Florquin S, Eosinophil-targeted therapy: not the panacea for antibody-mediated rejection?. AM J TRANSPLANT 2013;13 (10):2522-2523 [PubMed]
  • Lattenist L, Kers J, Claessen N, ten Berge IJM, Bemelman FJ, Florquin S, Roelofs JJTH, Renal and urinary levels of endothelial protein C receptor correlate with acute renal allograft rejection. PLOS ONE 2013;8 (5):e64994 [PubMed]
  • Rampanelli E, Dessing MC, Claessen N, Teske GJD, Joosten SPJ, Pals ST, Leemans JC, Florquin S, CD44-deficiency attenuates the immunologic responses to LPS and delays the onset of endotoxic shock-induced renal inflammation and dysfunction. PLOS ONE 2013;8 (12):e84479 [PubMed]
  • Rampanelli E, Rouschop K, Teske GJD, Claessen N, Leemans JC, Florquin S, CD44v3-v10 reduces the profibrotic effects of TGF-β1 and attenuates tubular injury in the early stage of chronic obstructive nephropathy. AM J PHYSIOL-RENAL 2013;305 (10):F1445-F1454 [PubMed]
  • Schreinemachers MCJM, Bemelman FJ, Idu MM, van Donselaar-van der Pant KAMI, van de Berg PJEJ, Reitsma JB, Legemate DA, Florquin S, ten Berge IJM, Doorschodt BM, van Gulik TM, First clinical experience with polysol solution: pilot study in living kidney transplantation. TRANSPL P 2013;45 (1):38-45 [PubMed]
  • Tammaro A, Stroo I, Rampanelli E, Blank F, Butter LM, Claessen N, Takai T, Colonna M, Leemans JC, Florquin S, Dessing MC, Role of TREM1-DAP12 in renal inflammation during obstructive nephropathy. PLOS ONE 2013;8 (12):e82498 [PubMed]
  • van Aalderen MC, Yapici Ü, van der Pol JA, de Reijke TM, van Donselaar-van der Pant KAMI, Florquin S, Bemelman FJ, ten Berge IJM, Polyomavirus BK in the pathogenesis of bladder cancer. NETH J MED 2013;71 (1):26-28 [PubMed]

2012

  • Achouiti A, Vogl T, Urban CF, Röhm M, Hommes TJ, van Zoelen MAD, Florquin S, Roth J, van 't Veer C, de Vos AF, van der Poll T, Myeloid-Related Protein-14 Contributes to Protective Immunity in Gram-Negative Pneumonia Derived Sepsis. PLOS PATHOG 2012;8 (10):e1002987 [PubMed]
  • Aslami H, Haitsma JJ, Hofstra JJ, Florquin S, Dos Santos C, Streutker C, Zhang H, Levi M, Slutsky AS, Schultz MJ, Plasma-derived human antithrombin attenuates ventilator-induced coagulopathy but not inflammation in a Streptococcus pneumoniae pneumonia model in rats. J THROMB HAEMOST 2012;10 (3):399-410 [PubMed]
  • Dessing MC, Pulskens WP, Teske GJ, Butter LM, van der Poll T, Yang H, Tracey KJ, Nawroth PP, Bierhaus A, Florquin S, Leemans JC, RAGE Does Not Contribute to Renal Injury and Damage upon Ischemia/Reperfusion-Induced Injury. J INNATE IMMUN 2012;4 (1):80-85 [PubMed]
  • Duitman J, Hoogendijk AJ, Groot AP, Ruela de Sousa RR, van der Poll T, Florquin S, Spek CA, CCAAT-Enhancer Binding Protein Delta (C/EBP delta) Protects Against Klebsiella pneumoniae-Induced Pulmonary Infection: Potential Role for Macrophage Migration. J INFECT DIS 2012;206 (12):1826-1835 [PubMed]
  • Duitman J, Schouten M, Groot AP, Daalhuisen JB, Florquin S, van der Poll T, Spek CA, CCAAT/enhancer-binding protein delta facilitates bacterial dissemination during pneumococcal pneumonia in a platelet-activating factor receptor-dependent manner. P NATL ACAD SCI USA 2012;109 (23):9113-9118 [PubMed]
  • Heutinck KM, Kassies J, Florquin S, ten Berge IJM, Hamann J, Rowshani AT, SerpinB9 expression in human renal tubular epithelial cells is induced by triggering of the viral dsRNA sensors TLR3, MDA5 and RIG-I. NEPHROL DIAL TRANSPL 2012;27 (7):2746-2754 [PubMed]
  • Heutinck KM, Rowshani AT, Kassies J, Claessen N, van Donselaar-van der Pant KAMI, Bemelman FJ, Eldering E, van Lier RAW, Florquin S, ten Berge IJM, Hamann J, Viral double-stranded RNA sensors induce antiviral, pro-inflammatory, and pro-apoptotic responses in human renal tubular epithelial cells. KIDNEY INT 2012;82 (6):664-675 [PubMed]
  • Hoogerwerf JJ, van der Windt GJW, Blok DC, Hoogendijk AJ, de Vos AF, van 't Veer C, Florquin S, Kobayashi KS, Flavell RA, van der Poll T, Interleukin-1 Receptor-Associated Kinase M-Deficient Mice Demonstrate an Improved Host Defense during Gram-negative Pneumonia. MOL MED 2012;18 (7):1067-1075 [PubMed]
  • Kager LM, van der Windt GJW, Wieland CW, Florquin S, van 't Veer C, van der Poll T, Plasminogen activator inhibitor type I may contribute to transient, non-specific changes in immunity in the subacute phase of murine tuberculosis. MICROBES INFECT 2012;14 (9):748-755 [PubMed]
  • Lammers AJJ, de Porto APNA, de Boer OJ, Florquin S, van der Poll T, The role of TLR2 in the host response to pneumococcal pneumonia in absence of the spleen. BMC INFECT DIS 2012;12 (1):139 [PubMed]
  • Leemans JC, Butter LM, Teske GJD, Stroo I, Pulskens WP, Florquin S, The Toll Interleukin-1 Receptor (IL-1R) 8/Single Ig Domain IL-1R-Related Molecule Modulates the Renal Response to Bacterial Infection. INFECT IMMUN 2012;80 (11):3812-3820 [PubMed]
  • Meijer-Jorna LB. Angiogenesis in congenital vascular malformations - a dynamic view on a static lesion -. s.l.: s.n.; 2012. 197p. ISBN 9789461908865 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Florquin S, van der Horst CMAM; copromotor(s): van der Wal AC)
  • Meijer-Jorna LB, van der Loos CM, Teeling P, de Boer OJ, Florquin S, van der Horst CMAM, van der Wal AC, Proliferation and maturation of microvessels in arteriovenous malformations - expression patterns of angiogenic and cell cycle-dependent factors. J CUTAN PATHOL 2012;39 (6):610-620 [PubMed]
  • Pulskens WPC. Pattern recognition receptors, sensing re(n)al danger. s.l.: s.n.; 2012. 203p. ISBN 9789090266664 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Florquin S; copromotor(s): Leemans JC)
  • Stroo I. Mechanisms of renal injury and repair. Role of stem cells, chemokines and the nodosome. s.l.: s.n.; 2012. 175p. ISBN 9789090264943 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Florquin S; copromotor(s): Leemans JC)
  • Stroo I, Butter LM, Claessen N, Teske GJ, Rubino SJ, Girardin SE, Florquin S, Leemans JC, Phenotyping of Nod1/2 double deficient mice and characterization of Nod1/2 in systemic inflammation and associated renal disease. BIOL OPEN 2012;1 (12):1239-1247 [PubMed]
  • Tonneijck L, Florquin S, Korte MR, Schut NH, Fibrosing Pericarditis in a Patient with Encapsulating Peritoneal Sclerosis. PERITON DIALYSIS INT 2012;32 (6):660-662 [PubMed]
  • van de Berg PJEJ, Hoevenaars EC, Yong SL, van Donselaar-van der Pant KAMI, van Tellingen A, Florquin S, van Lier RAW, Bemelman FJ, ten Berge IJM, Circulating lymphocyte subsets in different clinical situations after renal transplantation. IMMUNOLOGY 2012;136 (2):198-207 [PubMed]
  • van de Berg PJEJ, Yong SL, Koch SD, Lardy N, van Donselaar-van der Pant KAMI, Florquin S, Bemelman FJ, van Lier RAW, ten Berge IJM, Characteristics of alloreactive T cells measured before renal transplantation. CLIN EXP IMMUNOL 2012;168 (2):241-250 [PubMed]
  • van der Windt GJW, Blok DC, Hoogerwerf JJ, Lammers AJJ, de Vos AF, van't Veer C, Florquin S, Kobayashi KS, Flavell RA, van der Poll T, Interleukin 1 Receptor-Associated Kinase M Impairs Host Defense During Pneumococcal Pneumonia. J INFECT DIS 2012;205 (12):1849-1857 [PubMed]
  • van Zoelen MAD, Wieland CW, van der Windt GJW, Florquin S, Nawroth PP, Bierhaus A, van der Poll T, Receptor for advanced glycation end products is protective during murine tuberculosis. MOL IMMUNOL 2012;52 (3-4):183-189 [PubMed]
  • Yapici Ü, Roelofs JJTH, Florquin S, The Importance of Testing Anti-IL-17 Antibodies From Different Suppliers. AM J TRANSPLANT 2012;12 (2):504-505 [PubMed]

2011

  • de Boer OJ, Teeling P, Jansen M, Ploegmakers H, van der Loos CM, Kummer JA, Florquin S, van der Wal AC, Spatial Differences in the Presence of FOXP3(+) and GranzymeB(+) T Cells between the Intra- and Extravascular Compartments in Renal Allograft Vasculopathy. PLOS ONE 2011;6 (4):e18656 [PubMed]
  • Doorschodt BM, Schreinemachers MCJM, Behbahani M, Florquin S, Weis J, Staat M, Tolba RH, Hypothermic Machine Perfusion of Kidney Grafts: Which Pressure is Preferred?. ANN BIOMED ENG 2011;39 (3):1051-1059 [PubMed]
  • Hoogerwerf JJ, Leendertse M, Wieland CW, de Vos AF, de Boer JD, Florquin S, van der Poll T, Loss of Suppression of Tumorigenicity 2 (ST2) Gene Reverses Sepsis-induced Inhibition of Lung Host Defense in Mice. AM J RESP CRIT CARE 2011;183 (7):932-940 [PubMed]
  • Lammers AJ, de Porto AP, Florquin S, de Boer OJ, Bootsma HJ, Hermans PW, van der Poll T, Enhanced vulnerability for Streptococcus pneumoniae sepsis during asplenia is determined by the bacterial capsule. IMMUNOBIOLOGY 2011;216 (8):863-870 [PubMed]
  • van der Windt GJW, Hoogendijk AJ, de Vos AF, Kerver ME, Florquin S, van der Poll T, The role of CD44 in the acute and resolution phase of the host response during pneumococcal pneumonia. LAB INVEST 2011;91 (4):588-597 [PubMed]
  • van der Windt GJW, Hoogendijk AJ, Schouten M, Hommes TJ, de Vos AF, Florquin S, van der Poll T, Osteopontin Impairs Host Defense During Pneumococcal Pneumonia. J INFECT DIS 2011;203 (12):1850-1858 [PubMed]
  • van der Windt GJW, Schouten M, Zeerleder S, Florquin S, van der Poll T, CD44 Is Protective during Hyperoxia-Induced Lung Injury. AM J RESP CELL MOL 2011;44 (3):377-383 [PubMed]
  • van 't Veer C, van den Pangaart PS, Kruijswijk D, Florquin S, de Vos AF, van der Poll T, Delineation of the role of Toll-like receptor signaling during peritonitis by a gradually growing pathogenic Escherichia coli. J BIOL CHEM 2011;286 (42):36603-36618 [PubMed]
  • van Zoelen MAD, Verstege MI, Draing C, de Beer R, Veer CVt, Florquin S, Bresser P, van der Zee JS, te Velde AA, von Aulock S, van der Poll T, Endogenous MCP-1 promotes lung inflammation induced by LPS and LTA. MOL IMMUNOL 2011;48 (12-13):1468-1476 [PubMed]
  • Wösten-van Asperen RM, Lutter R, Specht PA, Moll GN, van Woensel JB, van der Loos CM, van Goor H, Kamilic J, Florquin S, Bos AP, Acute respiratory distress syndrome leads to reduced ratio of ACE/ACE2 activities and is prevented by angiotensin-(1-7) or an angiotensin II receptor antagonist. J PATHOL 2011;225 (4):618-627 [PubMed]
  • Yapici Ü, Kers J, Bemelman FJ, Roelofs JJTH, Groothoff JW, van der Loos CM, van Donselaar-van der Pant KAMI, Idu MM, Claessen N, ten Berge IJM, Florquin S, Interleukin-17 positive cells accumulate in renal allografts during acute rejection and are independent predictors of worse graft outcome. TRANSPL INT 2011;24 (10):1008-1017 [PubMed]

2010

  • Coppo R, Troyanov S, Camilla R, Hogg RJ, Cattran DC, Cook HT, Feehally J, Roberts ISD, Amore A, Alpers CE, Barratt J, Berthoux F, Bonsib S, Bruijn JA, D'Agati V, D'Amico G, Emancipator SN, Emma F, Ferrario F, Fervenza FC, Florquin S, Fogo AB, Geddes CC, Groene HJ, Haas M, Herzenberg AM, Hill PA, Hsu SI, Jennette JC, Joh K, Julian BA, Kawamura T, Lai FM, Li LS, Li PK, Liu ZH, Mezzano S, Schena FP, Tomino Y, Walker PD, Wang H, Weening JJ, Yoshikawa N, Zhang H, The Oxford IgA nephropathy clinicopathological classification is valid for children as well as adults. KIDNEY INT 2010;77 (10):921-927 [PubMed]
  • Cox-Brinkman J, van den Bergh Weerman MA, Wijburg FA, Aerts JMFG, Florquin S, van der Lee JH, Hollak CEM, Ultrastructural Analysis of Dermal Fibroblasts in Mucopolysaccharidosis Type I: Effects of Enzyme Replacement Therapy and Hematopoietic Cell Transplantation. ULTRASTRUCT PATHOL 2010;34 (3):126-132 [PubMed]
  • Dessing MC, Bemelman FJ, Claessen N, ten Berge IJM, Florquin S, Leemans JC, Intragraft Toll-like receptor profiling in acute renal allograft rejection. NEPHROL DIAL TRANSPL 2010;25 (12):4087-4092 [PubMed]
  • Dessing MC, Butter LM, Teske GJ, Claessen N, van der Loos CM, Vogl T, Roth J, van der Poll T, Florquin S, Leemans JC, S100A8/A9 Is Not Involved in Host Defense against Murine Urinary Tract Infection. PLOS ONE 2010;5 (10):e13394 [PubMed]
  • Kers J, Xu-Dubois YC, Rondeau E, Claessen N, Idu MM, Roelofs JJTH, Bemelman FJ, ten Berge IJM, Florquin S, Intragraft Tubular Vimentin and CD44 Expression Correlate With Long-Term Renal Allograft Function and Interstitial Fibrosis and Tubular Atrophy. TRANSPLANTATION 2010;90 (5):502-509 [PubMed]
  • Pulskens WP, Rampanelli E, Teske GJ, Butter LM, Claessen N, Luirink IK, Poll Tvd, Florquin S, Leemans JC, TLR4 Promotes Fibrosis but Attenuates Tubular Damage in Progressive Renal Injury. J AM SOC NEPHROL 2010;21 (8):1299-1308 [PubMed]
  • Schreinemachers MCJM. Preclinical evvaluation of a new organ preservation solution. s.l.: s.n.; 2010. 183p. ISBN 9789090253596 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Florquin S, Tolba R; copromotor(s): Bemelman FJ)
  • Schreinemachers MCJM, Doorschodt BM, Florquin S, van den Bergh Weerman MA, Zernecke A, Idu MM, Tolba RH, van Gulik TM, Pulsatile perfusion preservation of warm ischaemia-damaged experimental kidney grafts. BRIT J SURG 2010;97 (3):349-358 [PubMed]
  • Stokman G, Stroo I, Claessen N, Teske GJD, Florquin S, Leemans JC, SDF-1 provides morphological and functional protection against renal ischaemia/reperfusion injury. NEPHROL DIAL TRANSPL 2010;25 (12):3852-3859 [PubMed]
  • Stokman G, Stroo I, Claessen N, Teske GJD, Weening JJ, Leemans JC, Florquin S, Stem Cell Factor Expression after Renal Ischemia Promotes Tubular Epithelial Survival. PLOS ONE 2010;5 (12):e14386 [PubMed]
  • Stroo I, Stokman G, Teske GJD, Raven A, Butter LM, Florquin S, Leemans JC, Chemokine expression in renal ischemia/reperfusion injury is most profound during the reparative phase. INT IMMUNOL 2010;22 (6):433-442 [PubMed]
  • van der Meer JJ. The role of inflammation and infection in the pathogenesis of atheroclerosis. s.l.: s.n.; 2010. 129p. ISBN 9789090250786 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Florquin S; copromotor(s): van der Wal AC, de Boer OJ)
  • van der Windt GJW, Florquin S, de Vos AF, van't Veer C, Queiroz KCS, Liang J, Jiang D, Noble PW, van der Poll T, CD44 Deficiency Is Associated with Increased Bacterial Clearance but Enhanced Lung Inflammation During Gram-Negative Pneumonia. AM J PATHOL 2010;177 (5):2483-2494 [PubMed]
  • van der Windt GJW, Hoogerwerf JJ, de Vos AF, Florquin S, van der Poll T, Osteopontin promotes host defense during Klebsiella pneumoniae-induced pneumonia. EUR RESPIR J 2010;36 (6):1337-1345 [PubMed]
  • van der Windt GJW, van 't Veer C, Florquin S, van der Poll T, CD44 deficiency is associated with enhanced Escherichia coli-induced proinflammatory cytokine and chemokine release by peritoneal macrophages. INFECT IMMUN 2010;78 (1):115-124 [PubMed]
  • van der Windt GJW, Wiersinga WJ, Wieland CW, Tjia ICSI, Day NP, Peacock SJ, Florquin S, van der Poll T, Osteopontin Impairs Host Defense during Established Gram-Negative Sepsis Caused by Burkholderia pseudomallei (Melioidosis). PLOS NEGLECT TROP D 2010;4 (8):e806 [PubMed]
  • van Ham SM, Heutinck KM, Jorritsma T, Bemelman FJ, Strik MCM, Vos W, Muris JJF, Florquin S, ten Berge IJM, Rowshani AT, Urinary granzyme A mRNA is a biomarker to diagnose subclinical and acute cellular rejection in kidney transplant recipients. KIDNEY INT 2010;78 (10):1033-1040 [PubMed]
  • van Zoelen MAD, Achouiti A, Schmidt AM, Yang H, Florquin S, Tracey KJ, van der Poll T, Ligands of the receptor for advanced glycation end products, including high-mobility group box 1, limit bacterial dissemination during Escherichia coli peritonitis. CRIT CARE MED 2010;38 (6):1414-1422 [PubMed]
  • Wieland CW, Florquin S, van der Poll T, Toll-like receptor 9 is not important for host defense against Haemophilus influenzae. IMMUNOBIOLOGY 2010;215 (11):910-914 [PubMed]
  • Wiersinga WJ, Calandra T, Kager LM, van der Windt GJW, Roger T, le Roy D, Florquin S, Peacock SJ, Sweep FCGJ, van der Poll T, Expression and Function of Macrophage Migration Inhibitory Factor (MIF) in Melioidosis. PLOS NEGLECT TROP D 2010;4 (2):e605 [PubMed]
  • Wösten-van Asperen RM, Lutter R, Specht PAC, van Woensel JB, van der Loos CM, Florquin S, Lachmann B, Bos AP, Ventilator-Induced Inflammatory Response in Lipopolysaccharide-Exposed Rat Lung Is Mediated by Angiotensin-Converting Enzyme. AM J PATHOL 2010;176 (5):2219-2227 [PubMed]

2009

  • Baas MC, van Donselaar KAMI, Florquin S, van Binnendijk RS, ten Berge IJM, Bemelman FJ, Mumps: Not an Innocent Bystander in Solid Organ Transplantation. AM J TRANSPLANT 2009;9 (9):2186-2189 [PubMed]
  • Bos EM, Leuvenink HGD, Snijder PM, Kloosterhuis NJ, Hillebrands JL, Leemans JC, Florquin S, van Goor H, Hydrogen Sulfide-Induced Hypometabolism Prevents Renal Ischemia/Reperfusion Injury. J AM SOC NEPHROL 2009;20 (9):1901-1905 [PubMed]
  • Cattran DC, Coppo R, Cook HT, Feehally J, Roberts ISD, Troyanov S, Alpers CE, Amore A, Barratt J, Berthoux F, Bonsib S, Bruijn JA, D'Agati V, D'Amico G, Emancipator S, Emma F, Ferrario F, Fervenza FC, Florquin S, Fogo A, Geddes CC, Groene HJ, Haas M, Herzenberg AM, Hill PA, Hogg RJ, Hsu SI, Jennette JC, Joh K, Julian BA, Kawamura T, Lai FM, Leung CB, Li LS, Li PKT, Liu ZH, Mackinnon B, Mezzano S, Schena FP, Tomino Y, Walker PD, Wang H, Weening JJ, Yoshikawa N, Zhang H, The Oxford classification of IgA nephropathy: rationale, clinicopathological correlations, and classification. KIDNEY INT 2009;76 (5):534-545 [PubMed]
  • Doorschodt BM, Schreinemachers MCJM, Florquin S, Lai W, Sitzia M, Zernecke A, Tolba RH, Evaluation of a novel system for hypothermic oxygenated pulsatile perfusion preservation. INT J ARTIF ORGANS 2009;32 (10):728-738 [PubMed]
  • Florquin S. Membranoproliferatieve glomerulonefritis in: Bajema IM, Bruijn JA, editors. Praktische Nefropathologie 2009. Leiden: s.n.; 2009., p. 49-62
  • Florquin S. Tubulo-interstitiële nefritis in: Bajema IM, Bruijn JA, editors. Praktische Nefropathologie 2009. Leiden: s.n.; 2009., p. 179-196
  • Giebelen IAJ, Leendertse M, Florquin S, van der Poll T, Stimulation of acetylcholine receptors impairs host defence during pneumococcal pneumonia. EUR RESPIR J 2009;33 (2):375-381 [PubMed]
  • Iyer SS, Pulskens WP, Sadler JJ, Butter LM, Teske GJ, Ulland TK, Eisenbarth SC, Florquin S, Flavell RA, Leemans JC, Sutterwala FS, Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome. P NATL ACAD SCI USA 2009;106 (48):20388-20393 [PubMed]
  • Leemans JC, Butter LM, Pulskens WPC, Teske GJD, Claessen N, van der Poll T, Florquin S, The Role of Toll-Like Receptor 2 in Inflammation and Fibrosis during Progressive Renal Injury. PLOS ONE 2009;4 (5):e5704 [PubMed]
  • Leendertse M, Willems RJ, Giebelen IA, Florquin S, van den Pangaart PS, Bonten MJ, van der Poll T, Cecal ligation and puncture induced sepsis impairs host defense against Enterococcus faecium peritonitis. INTENS CARE MED 2009;35 (5):924-932 [PubMed]
  • Leendertse M, Willems RJL, Oei GA, Florquin S, Bonten MJM, van der Poll T, Intestinal Enterococcus faecium Colonization Improves Host Defense during Polymicrobial Peritonitis. J INFECT DIS 2009;200 (5):735-744 [PubMed]
  • Roberts ISD, Cook HT, Troyanov S, Alpers CE, Amore A, Barratt J, Berthoux F, Bonsib S, Bruijn JA, Cattran DC, Coppo R, D'Agati V, D'Amico G, Emancipator S, Emma F, Feehally J, Ferrario F, Fervenza FC, Florquin S, Fogo A, Geddes CC, Groene HJ, Haas M, Herzenberg AM, Hill PA, Hogg RJ, Hsu SI, Jennette JC, Joh K, Julian BA, Kawamura T, Lai FM, Li LS, Li PKT, Liu ZH, Mackinnon B, Mezzano S, Schena FP, Tomino Y, Walker PD, Wang H, Weening JJ, Yoshikawa N, Zhang H, The Oxford classification of IgA nephropathy: pathology definitions, correlations, and reproducibility. KIDNEY INT 2009;76 (5):546-556 [PubMed]
  • Roelofs JJ, Florquin S. Tubulointerstitial Injury in IgA Nephropathy in: Lai KN, editors. Recent Advances in IgA Nephropathy. Hong Kong, China: World Scientific Publishing Co. Pte. Ltd.; 2009., p. 55-68
  • Roelofs JJTH, Rouschop KMA, Teske GJD, Wagenaar GTM, Claessen N, Weening JJ, van der Poll T, Florquin S, Endogenous tissue-type plasminogen activator is protective during ascending urinary tract infection. NEPHROL DIAL TRANSPL 2009;24 (3):801-808 [PubMed]
  • Roelofs JJTH, Teske GJD, Bonta PI, de Vries CJM, Meijers JCM, Weening JJ, van der Poll T, Florquin S, Plasminogen activator inhibitor-1 regulates neutrophil influx during acute pyelonephritis. KIDNEY INT 2009;75 (1):52-59 [PubMed]
  • Schreinemachers MCJM, Doorschodt BM, Florquin S, Idu MM, Tolba RH, van Gulik TM, Improved renal function of warm ischemically damaged kidneys using polysol. TRANSPL P 2009;41 (1):32-35 [PubMed]
  • Schreinemachers MCJM, Doorschodt BM, Florquin S, Tolba RH, Comparison of Preservation Solutions for Washout of Kidney Grafts: An Experimental Study. TRANSPL P 2009;41 (10):4072-4079 [PubMed]
  • Schreinemachers MCJM, Doorschodt BM, Florquin S, van den Bergh Weerman MA, Reitsma JB, Lai W, Sitzia M, Minor TM, Tolba RH, van Gulik TM, Improved preservation and microcirculation with POLYSOL after transplantation in a porcine kidney autotransplantation model. NEPHROL DIAL TRANSPL 2009;24 (3):816-824 [PubMed]
  • Schut ES, Brouwer MC, de Gans J, Florquin S, Troost D, van de Beek D, Delayed cerebral thrombosis after initial good recovery from pneumococcal meningitis. NEUROLOGY 2009;73 (23):1988-1995 [PubMed]
  • Stegenga ME, Florquin S, de Vos AF, van der Poll T, The thiazolidinedione ciglitazone reduces bacterial outgrowth and early inflammation during Streptococcus pneumoniae pneumonia in mice. CRIT CARE MED 2009;37 (2):614-618 [PubMed]
  • Stroo I, Stokman G, Teske GJD, Florquin S, Leemans JC, Haematopoietic stem cell migration to the ischemic damaged kidney is not altered by manipulating the SDF-1/CXCR4-axis. NEPHROL DIAL TRANSPL 2009;24 (7):2082-2088 [PubMed]
  • van der Windt GJW, Wieland CW, Wiersinga WJ, Florquin S, van der Poll T, Osteopontin is not crucial to protective immunity during murine tuberculosis. IMMUNOLOGY 2009;128 (1 Suppl):e766-e776 [PubMed]
  • van Zoelen MAD, Florquin S, de Beer R, Pater JM, Verstege MI, Meijers JCM, van der Poll T, Urokinase Plasminogen Activator Receptor-Deficient Mice Demonstrate Reduced Hyperoxia-Induced Lung Injury. AM J PATHOL 2009;174 (6):2182-2189 [PubMed]
  • van Zoelen MAD, Schmidt AM, Florquin S, Receptor for advanced glycation end products facilitates host defense during Escherichia coli-induced abdominal sepsis in mice (vol 200, pg 765, 2009). J INFECT DIS 2009;200 (10):1629
  • van Zoelen MAD, Schmidt AM, Florquin S, Meijers JC, de Beer R, de Vos AF, Nawroth PP, Bierhaus A, van der Poll T, Receptor for Advanced Glycation End Products Facilitates Host Defense during Escherichia coli-Induced Abdominal Sepsis in Mice. J INFECT DIS 2009;200 (5):765-773 [PubMed]
  • van Zoelen MAD, Schouten M, de Vos AF, Florquin S, Meijers JCM, Nawroth PP, Bierhaus A, van der Poll T, The Receptor for Advanced Glycation End Products Impairs Host Defense in Pneumococcal Pneumonia. J IMMUNOL 2009;182 (7):4349-4356 [PubMed]
  • van Zoelen MAD, van der Sluijs KF, Achouiti A, Florquin S, Braun-Pater JM, Yang H, Nawroth PP, Tracey KJ, Bierhaus A, van der Poll T, Receptor for advanced glycation end products is detrimental during influenza A virus pneumonia. VIROLOGY 2009;391 (2):265-273 [PubMed]
  • van Zoelen MAD, Vogl T, Foell D, van Veen SQ, van Till JWO, Florquin S, Tanck MW, Wittebole X, Laterre PF, Boermeester MA, Roth J, van der Poll T, Expression and Role of Myeloid-related Protein-14 in Clinical and Experimental Sepsis. AM J RESP CRIT CARE 2009;180 (11):1098-1106 [PubMed]
  • van Zoelen MAD, Yang H, Florquin S, Meijers JCM, Akira S, Arnold B, Nawroth PP, Bierhaus A, Tracey KJ, van der Poll T, Role of toll-like receptors 2 and 4, and the receptor for advanced glycation end products in high-mobility group box 1-induced inflammation in vivo. SHOCK 2009;31 (3):280-284 [PubMed]
  • Wieland CW, van der Windt GJW, Florquin S, McKenzie ANJ, van der Poll T, ST2 deficient mice display a normal host defense against pulmonary infection with Mycobacterium tuberculosis. MICROBES INFECT 2009;11 (4):524-530 [PubMed]
  • Yapici U, Bemelman FJ, Scheepstra CG, Roelofs JJTH, Claessen N, van der Loos C, van Donselaar-van der Pant K, Bouts AHM, Idu MM, Rowshani AT, ten Berge IJM, Florquin S, Intragraft FOXP3 Protein or mRNA During Acute Renal Allograft Rejection Correlates With Inflammation, Fibrosis, and Poor Renal Outcome. TRANSPLANTATION 2009;87 (9):1377-1380 [PubMed]

2008

  • Alegre ML, Leemans J, Le Moine A, Florquin S, de Wilde V, Chong A, Goldman M, The multiple facets of toll-like receptors in transplantation biology. TRANSPLANTATION 2008;86 (1):1-9 [PubMed]
  • Buonocore S, Haddou NO, Moore F, Florquin S, Paulart F, Heirman C, Thielemans K, Goldman M, Flamand V, Neutrophil-dependent tumor rejection and priming of tumoricidal CD8+ T cell response induced by dendritic cells overexpressing CD95L. J LEUKOCYTE BIOL 2008;84 (3):713-720 [PubMed]
  • Celie JWAM, Reijmers RM, Slot EM, Beelen RHJ, Spaargaren M, ter Wee PM, Florquin S, van den Born J, Tubulointerstitial heparan sulfate proteoglycan changes in human renal diseases correlate with leukocyte influx and proteinuria. AM J PHYSIOL-RENAL 2008;294 (1):F253-F263 [PubMed]
  • Choi G, Hofstra JJH, Roelofs JJTH, Rijneveld AW, Bresser P, van der Zee JS, Florquin S, van der Poll T, Levi M, Schultz MJ, Antithrombin inhibits bronchoalveolar activation of coagulation and limits lung injury during Streptococcus pneumoniae pneumonia in rats. CRIT CARE MED 2008;36 (1):204-210 [PubMed]
  • Dessing MC, Florquin S, Paton JC, van der Poll T, Toll-like receptor 2 contributes to antibacterial defence against pneumolysin-deficient pneumococci. CELL MICROBIOL 2008;10 (1):237-246 [PubMed]
  • Florquin S. Membranoproliferatieve glomerulonefritis in: Bajema IM, Bruijn JA, editors. Praktische nefropathologie 2008. Leiden: Boerhaave Commissie vor Postacademisch Onderwijs in de Geneeskunde, Leids Universitair Medisch Centrum; 2008., p. 47-60
  • Florquin S. Tubulo-interstitiële nefritis in: Bajema IM, Bruijn JA, editors. Praktische nefropathologie 2008. Leiden: Boerhaave Commissie vor Postacademisch Onderwijs in de Geneeskunde, Leids Universitair Medisch Centrum; 2008., p. 175-190
  • Giebelen IAJ, Le Moine A, van den Pangaart PS, Sadis C, Goldman M, Florquin S, van der Poll T, Deficiency of alpha7 cholinergic receptors facilitates bacterial clearance in Escherichia coli peritonitis. J INFECT DIS 2008;198 (5):750-757 [PubMed]
  • Grootscholten C, Bajema IM, Florquin S, Steenbergen EJ, Peutz-Kootstra CJ, Goldschmeding R, Bijl M, Hagen EC, van Houwelingen HC, Derksen RHWM, Berden JHM, Interobserver agreement of scoring of histopathological characteristics and classification of lupus nephritis. NEPHROL DIAL TRANSPL 2008;23 (1):223-230 [PubMed]
  • Leendertse M, Willems RJL, Giebelen IAJ, van den Pangaart PS, Wiersinga WJ, de Vos AF, Florquin S, Bonten MJM, van der Poll T, TLR2-dependent MyD88 signaling contributes to early host defense in murine Enterococcus faecium peritonitis. J IMMUNOL 2008;180 (7):4865-4874 [PubMed]
  • Pulskens WP, Teske GJ, Butter LM, Roelofs JJ, van der Poll T, Florquin S, Leemans JC, Toll-Like Receptor-4 Coordinates the Innate Immune Response of the Kidney to Renal Ischemia/Reperfusion Injury. PLOS ONE 2008;3 (10):e3596 [PubMed]
  • Renckens R, Roelofs JJTH, Stegenga ME, Florquin S, Levi M, Carmeliet P, van't Veer C, van der Poll T, Transgenic tissue-type plasminogen activator expression improves host defense during Klebsiella pneumonia. J THROMB HAEMOST 2008;6 (4):660-668 [PubMed]
  • Renckens R, van Westerloo DJ, Roelofs JJTH, Pater JM, Schultz MJ, Florquin S, van der Poll T, Acute phase response impairs host defense against Pseudomonas aeruginosa pneumonia in mice. CRIT CARE MED 2008;36 (2):580-587 [PubMed]
  • Roelofs JJ, Abramowicz D, Florquin S. Immunomodulators: interleukins, interferons, and IV immunoglobulin in: De Broe ME, Porter GA, Bennett WM, Deray G, editors. Clinical Nephrotoxins - Renal Injury from Drugs and Chemicals, Third Edition. S.l.: Springer; 2008., p. 683-698
  • Scheepstra C, Bemelman FJ, van der Loos C, Rowshani AT, van Donselaar-van der Pant KAMI, Idu MM, ten Berge IJM, Florquin S, B cells in cluster or in a scattered pattern do not correlate with clinical outcome of renal allograft rejection. TRANSPLANTATION 2008;86 (6):772-778 [PubMed]
  • Stokman G. Mechanisms of tubular damage and repair in renal injury. s.l.: s.n.; 2008. 157p. ISBN 9789090231013 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Florquin S, Weening JJ; copromotor(s): Leemans JC)
  • Stokman G, Leemans JC, Stroo I, Hoedemaeker I, Claessen N, Teske GJD, Weening JJ, Florquin S, Enhanced mobilization of bone marrow cells does not ameliorate renal fibrosis. NEPHROL DIAL TRANSPL 2008;23 (2):483-491 [PubMed]
  • van Zoelen MAD, Florquin S, Meijers JCM, de Beer R, de Vos AF, de Boer OJ, van der Poll T, Platelet-activating factor receptor contributes to host defense against Pseudomonas aeruginosa pneumonia but is not essential for the accompanying inflammatory and procoagulant response. J IMMUNOL 2008;180 (5):3357-3365 [PubMed]
  • Wieland CW, van der Windt GJW, Wiersinga WJ, Florquin S, van der Poll T, CD14 contributes to pulmonary inflammation and mortality during murine tuberculosis. IMMUNOLOGY 2008;125 (2):272-279 [PubMed]
  • Wösten-van Asperen RM, Lutter R, Haitsma JJ, Merkus MP, van Woensel JB, Florquin S, Lachmann B, Bos AP, Pulmonary Angiotensin-converting Enzyme Mediates Ventilator-induced Lung Injury in Rats. PROC AM THORAC SOC 2008;5 (3):371 [PubMed]
  • Wösten-van Asperen RM, Lutter R, Haitsma JJ, Merkus MP, van Woensel JB, van der Loos CM, Florquin S, Lachmann B, Bos AP, ACE mediates ventilator-induced lung injury in rats via angiotensin II but not bradykinin. EUR RESPIR J 2008;31 (2):363-371 [PubMed]

2007

  • Alegre ML, Florquin S, Goldman M, Cellular mechanisms underlying acute graft rejection: time for reassessment. CURR OPIN IMMUNOL 2007;19 (5):563-568 [PubMed]
  • Celie JWAM, Rutjes NWP, Keuning ED, Soininen R, Heljasvaara R, Pihlajaniemi T, Dräger AM, Zweegman S, Kessler FL, Beelen RHJ, Florquin S, Aten J, van den Born J, Subendothelial heparan sulfate proteoglycans become major L-selectin and monocyte chemoattractant protein-1 ligands upon renal ischemia/reperfusion. AM J PATHOL 2007;170 (6):1865-1878 [PubMed]
  • Choi G, Hofstra JJH, Roelofs JJTH, Florquin S, Bresser P, Levi M, van der Poll T, Schultz MJ, Recombinant human activated protein C inhibits local and systemic activation of coagulation without influencing inflammation during Pseudomonas aeruginosa pneumonia in rats. CRIT CARE MED 2007;35 (5):1362-1368 [PubMed]
  • Dessing MC, Knapp S, Florquin S, de Vos AF, van der Poll T, CD14 facilitates invasive respiratory tract infection by Streptococcus pneumoniae. AM J RESP CRIT CARE 2007;175 (6):604-611 [PubMed]
  • Dessing MC, van der Sluijs KF, Florquin S, Akira S, van der Poll T, Toll-like receptor 2 does not contribute to host response during postinfluenza pneumococcal pneumonia. AM J RESP CELL MOL 2007;36 (5):609-614 [PubMed]
  • Dessing MC, van der Sluijs KF, Florquin S, van der Poll T, CD14 plays a limited role during influenza A virus infection in vivo. IMMUNOL LETT 2007;113 (1):47-51 [PubMed]
  • Dessing MC, van der Sluijs KF, Florquin S, van der Poll T, Monocyte chemoattractant protein 1 contributes to an adequate immune response in influenza pneumonia. CLIN IMMUNOL 2007;125 (3):328-336 [PubMed]
  • Dinant S, Vetelainen RL, Florquin S, van Vliet AK, van Gulik TM, IL-10 attenuates hepatic I/R injury and promotes hepatocyte proliferation. J SURG RES 2007;141 (2):176-182 [PubMed]
  • Grootscholten C, Bajema IM, Florquin S, Steenbergen EJ, Peutz-Kootstra CJ, Goldschmeding R, Bijl M, Hagen EC, van Houwelingen HC, Derksen RHWM, Berden JHM, Treatment with cyclophosphamide delays the progression of chronic lesions more effectively than does treatment with azathioprine plus methylprednisolone in patients with proliferative lupus nephritis. ARTHRITIS RHEUM-US 2007;56 (3):924-937 [PubMed]
  • Renckens R, Roelofs JJTH, Bonta PI, Florquin S, de Vries CJM, Levi M, Carmeliet P, van't Veer C, van der Poll T, Plasminogen activator inhibitor type 1 is protective during severe Gram-negative pneumonia. BLOOD 2007;109 (4):1593-1601 [PubMed]
  • Roelofs JJTH. The fibrinolytic system in renal disease. s.l.: s.n.; 2007. 157p. ISBN 9789090219110 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Florquin S, Weening JJ; copromotor(s): )
  • Sadis C, Teske G, Stokman G, Kubjak C, Claessen N, Moore F, Loi P, Diallo B, Barvais L, Goldman M, Florquin S, Le Moine A, Nicotine protects kidney from renal ischemia/reperfusion injury through the cholinergic anti-inflammatory pathway. PLOS ONE 2007;2 (5):e469 [PubMed]
  • van Well GTJ, Wieland CW, Florquin S, Roord JJ, van der Poll T, van Furth AM, A new murine model to study the pathogenesis of tuberculous meningitis. J INFECT DIS 2007;195 (5):694-697 [PubMed]
  • Wieland CW, Florquin S, van der Poll T, Interleukin 18 participates in the early inflammatory response and bacterial clearance during pneumonia caused by nontypeable Haemophilus influenzae. INFECT IMMUN 2007;75 (10):5068-5072 [PubMed]
  • Wieland CW, Koppel EA, den Dunnen J, Florquin S, McKenzie ANJ, van Kooyk Y, van der Poll T, Geijtenbeek TBH, Mice lacking SIGNR1 have stronger T helper 1 responses to Mycobacterium tuberculosis. MICROBES INFECT 2007;9 (2):134-141 [PubMed]
  • Wiersinga WJ, Wieland CW, Dessing MC, Chantratita N, Cheng AC, Limmathurotsakul D, Chierakul W, Leendertse M, Florquin S, de Vos AF, White N, Dondorp AM, Day NP, Peacock SJ, van der Poll T, Toll-like receptor 2 impairs host defense in gram-negative sepsis caused by Burkholderia pseudomallei (Melioidosis). PLOS MED 2007;4 (7):e248-1280 [PubMed]
  • Wiersinga WJ, Wieland CW, van der Windt GJW, de Boer A, Florquin S, Dondorp A, Day NP, Peacock SJ, van der Poll T, Endogenous interleukin-18 improves the early antimicrobial host response in severe melioidosis. INFECT IMMUN 2007;75 (8):3739-3746 [PubMed]
  • Zwijnenburg PJG, van der Poll T, Florquin S, Polfliet MMJ, van den Berg TK, Dijkstra CD, Roord JJ, Hack CE, van Furth AM, C1 inhibitor treatment improves host defense in pneumococcal meningitis in rats and mice. J INFECT DIS 2007;196 (1):115-123 [PubMed]

2006

  • Davin JC, Olie KH, Verlaak R, Horuz F, Florquin S, Weening JJ, Groothoff JW, Strain L, Goodship THJ, Complement factor H-associated atypical hemolytic uremic syndrome in monozygotic twins: concordant presentation, discordant response to treatment. AM J KIDNEY DIS 2006;47 (2):e27-e30 [PubMed]
  • Dessing MC, de Vos AF, Florquin S, van der Poll T, Monocyte chemoattractant protein 1 does not contribute to protective immunity against pneumococcal pneumonia. INFECT IMMUN 2006;74 (12):7021-7023 [PubMed]
  • de Waard V, Hansen HR, Spronk HHM, Timmerman JJ, Pannekoek H, Florquin S, Reitsma PH, ten Cate H, Differential expression of tissue factor mRNA and protein expression in murine sepsis. The role of the granulocyte revisited. THROMB HAEMOSTASIS 2006;95 (2):348-353 [PubMed]
  • Keller TT, van der Sluijs KF, de Kruif MD, Gerdes VEA, Meijers JCM, Florquin S, van der Poll T, van Gorp ECM, Brandjes DPM, Büller HR, Levi M, Effects on coagulation and fibrinolysis induced by influenza in mice with a reduced capacity to generate activated protein C and a deficiency in plasminogen activator inhibitor type 1. CIRC RES 2006;99 (11):1261-1269 [PubMed]
  • Knapp S, Florquin S, Golenbock DT, van der Poll T, Pulmonary lipopolysaccharide (LPS)-binding protein inhibits the LPS-induced lung inflammation in vivo. J IMMUNOL 2006;176 (5):3189-3195 [PubMed]
  • Knapp S, Wieland CW, Florquin S, Pantophlet R, Dijkshoorn L, Tshimbalanga N, Akira S, van der Poll T, Differential roles of CD14 and toll-like receptors 4 and 2 in murine Acinetobacter pneumonia. AM J RESP CRIT CARE 2006;173 (1):122-129 [PubMed]
  • Leemans JC, Wieland CW, Florquin S, van der Poll T, Vervoordeldonk MJBM, Mice overexpressing p40 in lungs have reduced leucocyte influx and slightly impaired resistance during tuberculosis. IMMUNOLOGY 2006;117 (3):409-418 [PubMed]
  • Maris NA, Florquin S, van't Veer C, de Vos AF, Buurman W, Jansen HM, van der Poll T, Inhalation of beta 2 agonists impairs the clearance of nontypable Haemophilus influenzae from the murine respiratory tract. RESP RES 2006;7:57 [PubMed]
  • Renckens R, Roelofs JJTH, Florquin S, de Vos AF, Lijnen HR, van't Veer C, van der Poll T, Matrix metalloproteinase-9 deficiency impairs host defense against abdominal sepsis. J IMMUNOL 2006;176 (6):3735-3741 [PubMed]
  • Renckens R, Roelofs JJTH, Florquin S, de Vos AF, Pater JM, Lijnen HR, Carmeliet P, van 't Veer C, van der Poll T, Endogenous tissue-type plasminogen activator is protective during Escherichia coli-induced abdominal sepsis in mice. J IMMUNOL 2006;177 (2):1189-1196 [PubMed]
  • Renckens R, Roelofs JJTH, Florquin S, van der Poll T, Urokinase-type plasminogen activator receptor plays a role in neutrophil migration during lipopolysaccharide-induced peritoneal inflammation but not during Escherichia coli-induced peritonitis. J INFECT DIS 2006;193 (4):522-530 [PubMed]
  • Renckens R, Roelofs JJTH, Knapp S, de Vos AF, Florquin S, van der Poll T, The acute-phase response and serum amyloid A inhibit the inflammatory response to Acinetobacter baumannii Pneumonia. J INFECT DIS 2006;193 (2):187-195 [PubMed]
  • Rijneveld AW, Weijer S, Bresser P, Florquin S, Vlasuk GP, Rote WE, Spek CA, Reitsma PH, van der Zee JS, Levi M, van der Poll T, Local activation of the tissue factor-factor VIIa pathway in patients with pneumonia and the effect of inhibition of this pathway in murine pneumococcal pneumonia. CRIT CARE MED 2006;34 (6):1725-1730 [PubMed]
  • Roelofs JJTH, Rouschop KMA, Leemans JC, Claessen N, de Boer AM, Frederiks WM, Lijnen HR, Weening JJ, Florquin S, Tissue-type plasminogen activator modulates inflammatory responses and renal function in ischemia reperfusion injury. J AM SOC NEPHROL 2006;17 (1):131-140 [PubMed]
  • Roelofs JJTH, Rouschop KMA, Teske GJD, Claessen N, Weening JJ, van der Poll T, Florquin S, The urokinase plasminogen activator receptor is crucially involved in host defense during acute pyelonephritis. KIDNEY INT 2006;70 (11):1942-1947 [PubMed]
  • Roos-van Groningen MC, Scholten EM, Lelieveld PM, Rowshani AT, Baelde HJ, Bajema IM, Florquin S, Bemelman FJ, de Heer E, de Fijter JW, Bruijn JA, Eikmans M, Molecular comparison of calcineurin inhibitor-induced fibrogenic responses in protocol renal transplant biopsies. J AM SOC NEPHROL 2006;17 (3):881-888 [PubMed]
  • Rouschop KMA. CD44 in renal disease: friend or foe?. S.l.: s.n.; 2006. 171p. ISBN 9789052910956 [UvA Dissertations Online] Proefschrift Universiteit van Amsterdam. (Promotor(s): Weening JJ, Pals ST; copromotor(s): Florquin S)
  • Rouschop KMA, Claessen N, Pals ST, Weening JJ, Florquin S, CD44 disruption prevents degeneration of the capillary network in obstructive nephropathy via reduction of TGF-beta1-induced apoptosis. J AM SOC NEPHROL 2006;17 (3):746-753 [PubMed]
  • Rouschop KMA, Roelofs JJTH, Sylva M, Rowshani AT, ten Berge IJM, Weening JJ, Florquin S, Renal expression of CD44 correlates with acute renal allograft rejection. KIDNEY INT 2006;70 (6):1127-1134 [PubMed]
  • Rouschop KMA, Sylva M, Teske GJD, Hoedemaeker I, Pals ST, Weening JJ, van der Poll T, Florquin S, Urothelial CD44 facilitates Escherichia coli infection of the murine urinary tract. J IMMUNOL 2006;177 (10):7225-7232 [PubMed]
  • Rowshani AT, Scholten EM, Bemelman F, Eikmans M, Idu M, Roos-van Groningen MC, van Groningen MCR, Surachno JS, Mallat MJK, Paul LC, de Fijter JW, Bajema IM, ten Berge I, Florquin S, No difference in degree of interstitial Sirius red-stained area in serial biopsies from area under concentration-over-time curves-guided cyclosporine versus tacrolimus-treated renal transplant recipients at one year. J AM SOC NEPHROL 2006;17 (1):305-312 [PubMed]
  • Scholten EM, Rowshani AT, Cremers S, Bemelman FJ, Eikmans M, van Kan E, Mallat MJ, Florquin S, Surachno J, ten Berge IJ, Bajema IM, de Fijter JW, Untreated rejection in 6-month protocol biopsies is not associated with fibrosis in serial biopsies or with loss of graft function. J AM SOC NEPHROL 2006;17 (9):2622-2632 [PubMed]
  • van der Sluijs KF, Nijhuis M, Levels JHM, Florquin S, Mellor AL, Jansen HM, van der Poll T, Lutter R, Influenza-induced expression of indoleamine 2,3-dioxygenase enhances interleukin-10 production and bacterial outgrowth during secondary pneumococcal pneumonia. J INFECT DIS 2006;193 (2):214-222 [PubMed]
  • van der Sluijs KF, van Elden LJR, Nijhuis M, Schuurman R, Florquin S, Shimizu T, Ishii S, Jansen HM, Lutter R, van der Poll T, Involvement of the platelet-activating factor receptor in host defense against Streptococcus pneumoniae during postinfluenza pneumonia. AM J PHYSIOL-LUNG C 2006;290 (1):L194-L199 [PubMed]
  • van der Sluijs KF, van Elden LJR, Xiao Y, Arens R, Nijhuis M, Schuurman R, Florquin S, Jansen HM, Lutter R, van der Poll T, IL-12 deficiency transiently improves viral clearance during the late phase of respiratory tract infection with influenza A virus in mice. ANTIVIR RES 2006;70 (2):75-84 [PubMed]
  • van Veen SQ, Levi M, van Vliet AK, Florquin S, van Gulik TM, Boermeester MA, Peritoneal lavage with activated protein C alters compartmentalized coagulation and fibrinolysis and improves survival in polymicrobial peritonitis. CRIT CARE MED 2006;34 (11):2799-2805 [PubMed]
  • van Westerloo DJ, Giebelen IA, Florquin S, Bruno MJ, Larosa GJ, Ulloa L, Tracey KJ, van der Poll T, The vagus nerve and nicotinic receptors modulate experimental pancreatitis severity in mice. GASTROENTEROLOGY 2006;130 (6):1822-1830 [PubMed]
  • Vedder AC, Strijland A, van den Bergh Weerman MA, Florquin S, Aerts JMFG, Hollak CEM, Manifestations of Fabry disease in placental tissue. J INHERIT METAB DIS 2006;29 (1):106-111 [PubMed]
  • Wieland CW, Florquin S, Pater JM, Weijer S, van der Poll T, CD4+ cells play a limited role in murine lung infection with Mycobacterium kansasii. AM J RESP CELL MOL 2006;34 (2):167-173 [PubMed]
  • Wieland CW, Florquin S, Pater JM, Weijer S, van der Poll T, Interleukin-1 contributes to an effective clearance of Mycobacterium kansasii from the respiratory tract. MICROBES INFECT 2006;8 (9-10):2409-2413 [PubMed]
  • Wieland CW, Kerver ME, Florquin S, Nolte MA, Borst J, van Lier R, van Oers MHJ, van der Poll T, CD27 contributes to the early systemic immune response to Mycobacterium tuberculosis infection but does not affect outcome. INT IMMUNOL 2006;18 (11):1531-1539 [PubMed]
  • Wieland CW, Stegenga ME, Florquin S, Fantuzzi G, van der Poll T, Leptin and host defense against Gram-positive and Gram-negative pneumonia in mice. SHOCK 2006;25 (4):414-419 [PubMed]

2005

  • Branger J, Leemans JC, Florquin S, Speelman P, Golenbock DT, van der Poll T, Lipopolysaccharide binding protein-deficient mice have a normal defense against pulmonary mycobacterial infection. CLIN IMMUNOL 2005;116 (2):174-181 [PubMed]
  • Koppel EA, Wieland CW, van den Berg VCM, Litjens M, Florquin S, van Kooyk Y, van der Poll T, Geijtenbeek TBH, Specific ICAM-3 grabbing nonintegrin-related 1 (SIGNR1) expressed by marginal zone macrophages is essential for defense against pulmonary Streptococcus pneumoniae infection. EUR J IMMUNOL 2005;35 (10):2962-2969 [PubMed]
  • Leemans JC, Stokman G, Claessen N, Rouschop KM, Teske GJD, Kirschning CJ, Akira S, van der Poll T, Weening JJ, Florquin S, Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney. J CLIN INVEST 2005;115 (10):2894-2903 [PubMed]
  • Leemans JC, Thepen T, Weijer S, Florquin S, van Rooijen N, van de Winkel JG, van der Poll T, Macrophages play a dual role during pulmonary tuberculosis in mice. J INFECT DIS 2005;191 (1):65-74 [PubMed]
  • Olie KH, Goodship THJ, Verlaak R, Florquin S, Groothoff JW, Strain L, Weening JJ, Davin JC, Posttransplantation cytomegalovirus-induced recurrence of atypical hemolytic uremic syndrome associated with a factor H mutation: Successful treatment with intensive plasma exchanges and ganciclovir. AM J KIDNEY DIS 2005;45 (1):E12-E15 [PubMed]
  • Renckens R, Roelofs JJTH, de Waard V, Florquin S, Lijnen HR, Carmeliet P, van der Poll T, The role of plasminogen activator inhibitor type 1 in the inflammatory response to local tissue injury. J THROMB HAEMOST 2005;3 (5):1018-1025 [PubMed]
  • Renckens R, Roelofs JJTH, ter Horst SAJ, van 't Veer C, Havik SR, Florquin S, Wagenaar GTM, Meijers JCM, van der Poll T, Absence of thrombin-activatable fibrinolysis inhibitor protects against sepsis-induced liver injury in mice. J IMMUNOL 2005;175 (10):6764-6771 [PubMed]
  • Rijneveld AW, de Vos AF, Florquin S, Verbeek JS, van der Poll T, CD11b limits bacterial outgrowth and dissemination during murine pneumococcal pneumonia. J INFECT DIS 2005;191 (10):1755-1760 [PubMed]
  • Rouschop KMA, Roelofs JJTH, Claessen N, da Costa Martins P, Zwaginga JJ, Pals ST, Weening JJ, Florquin S, Protection against renal ischemia reperfusion injury by CD44 disruption. J AM SOC NEPHROL 2005;16 (7):2034-2043 [PubMed]
  • Rouschop KMA, Roelofs JJTH, Rowshani AT, Leemans JC, van der Poll T, ten Berge IJM, Weening JJ, Florquin S, Pre-transplant plasma and cellular levels of CD44 correlate with acute renal allograft rejection. NEPHROL DIAL TRANSPL 2005;20 (10):2248-2254 [PubMed]
  • Sommeijer DW, Florquin S, Hoedemaker I, Timmerman JJ, Reitsma PH, ten Cate H, Renal tissue factor expression is increased in streptozotocin-induced diabetic mice. NEPHRON EXP NEPHROL 2005;101 (3):86-94 [PubMed]
  • Stokman G, Leemans JC, Claessen N, Weening JJ, Florquin S, Hematopoietic stem cell mobilization therapy accelerates recovery of renal function independent of stem cell contribution. J AM SOC NEPHROL 2005;16 (6):1684-1692 [PubMed]
  • van der Sluijs KF, van Elden LJR, Arens R, Nijhuis M, Schuurman R, Florquin S, Kwakkel J, Akira S, Jansen HM, Lutter R, van der Polls T, Enhanced viral clearance in interleukin-18 gene-deficient mice after pulmonary infection with influenza A virus. IMMUNOLOGY 2005;114 (1):112-120 [PubMed]
  • van Westerloo DJ, Florquin S, de Boer AM, Daalhuisen J, de Vos AF, Bruno MJ, van der Poll T, Therapeutic effects of troglitazone in experimental chronic pancreatitis in mice. AM J PATHOL 2005;166 (3):721-728 [PubMed]
  • van Westerloo DJ, Giebelen IAJ, Florquin S, Daalhuisen J, Bruno MJ, de Vos AF, Tracey KJ, van der Poll T, The cholinergic anti-inflammatory pathway regulates the host response during septic peritonitis. J INFECT DIS 2005;191 (12):2138-2148 [PubMed]
  • van Westerloo DJ, Knapp S, van't Veer C, Buurman WA, de Vos AF, Florquin S, van der Poll T, Aspiration pneumonitis primes the host for an exaggerated inflammatory response during pneumonia. CRIT CARE MED 2005;33 (8):1770-1778 [PubMed]
  • Weijer S, Florquin S, van der Poll T, Endogenous interleukin-12 improves the early antimicrobial host response to murine Escherichia coli peritonitis. SHOCK 2005;23 (1):54-58 [PubMed]
  • Weijer S, Wieland CW, Florquin S, van der Poll T, A thrombomodulin mutation that impairs activated protein C generation results in uncontrolled lung inflammation during murine tuberculosis. BLOOD 2005;106 (8):2761-2768 [PubMed]
  • Wieland CW, Florquin S, Chan ED, Leemans JC, Weijer S, Verbon A, Fantuzzi G, van der Poll T, Pulmonary Mycobacterium tuberculosis infection in leptin-deficient ob/ob mice. INT IMMUNOL 2005;17 (11):1399-1408 [PubMed]
  • Wieland CW, Florquin S, Maris NA, Hoebe K, Beutler B, Takeda K, Akira S, van der Poll T, The MyD88-dependent, but not the MyD88-independent, pathway of TLR4 signaling is important in clearing nontypeable Haemophilus influenzae from the mouse lung. J IMMUNOL 2005;175 (9):6042-6049 [PubMed]

2004

  • Branger J, Florquin S, Knapp S, Leemans JC, Pater JM, Speelman P, Golenbock DT, van der Poll T, LPS-binding protein-deficient mice have an impaired defense against Gram-negative but not Gram-positive pneumonia. INT IMMUNOL 2004;16 (11):1605-1611 [PubMed]
  • Branger J, Knapp S, Weijer S, Leemans JC, Pater JM, Speelman P, Florquin S, van der Poll T, Role of Toll-like receptor 4 in gram-positive and gram-negative pneumonia in mice. INFECT IMMUN 2004;72 (2):788-794 [PubMed]
  • Branger J, Leemans JC, Florquin S, Weijer S, Speelman P, van der Poll T, Toll-like receptor 4 plays a protective role in pulmonary tuberculosis in mice. INT IMMUNOL 2004;16 (3):509-516 [PubMed]
  • Branger J, Wieland CW, Florquin S, Maris NA, Pater JM, Speelman P, Shimizu T, Ishii S, van der Poll T, Platelet-activating factor receptor-deficient mice show an unaltered clearance of nontypeable Haemophilus influenzae from their respiratory tract. SHOCK 2004;22 (6):543-547 [PubMed]
  • Buonocore S, Flamand V, Claessen N, Heeringa P, Goldman M, Florquin S, Dendritic cells overexpressing Fas-ligand induce pulmonary vasculitis in mice. CLIN EXP IMMUNOL 2004;137 (1):74-80 [PubMed]
  • Florquin S. Membranoproliferatieve glomerulonefritis in: Bruijn JA, editor. Praktische nefropathologie. Leiden: LUMC; 2004., p. 65-78
  • Florquin S. Tubulo-interstitiële nefritis in: Bruijn JA, editor. Praktische nefropathologie. Leiden: LUMC; 2004., p. 163-178
  • Knapp S, Hareng L, Rijneveld AW, Bresser P, van der Zee JS, Florquin S, Hartung T, van der Poll T, Activation of neutrophils and inhibition of the proinflammatory cytokine response by endogenous granulocyte colony-stimulating factor in murine pneumococcal pneumonia. J INFECT DIS 2004;189 (8):1506-1514 [PubMed]
  • Knapp S, Wieland CW, van 't Veer C, Takeuchi O, Akira S, Florquin S, van der Poll T, Toll-like receptor 2 plays a role in the early inflammatory response to murine pneumococcal pneumonia but does not contribute to antibacterial defense. J IMMUNOL 2004;172 (5):3132-3138 [PubMed]
  • Leemans JC, te Velde AA, Florquin S, Bennink RJ, de Bruin K, van Lier RAW, van der Poll T, Hamann J, The epidermal growth factor-seven transmembrane (EGF-TM7) receptor CD97 is required for neutrophil migration and host defense. J IMMUNOL 2004;172 (2):1125-1131 [PubMed]
  • Maris NA, van der Sluijs KF, Florquin S, de Vos AF, Pater JM, Jansen HM, van der Poll T, Salmeterol, a beta(2)-receptor agonist, attenuates lipopolysaccharide-induced lung inflammation in mice. AM J PHYSIOL-LUNG C 2004;286 (6):L1122-L1128 [PubMed]
  • Olie KH, Florquin S, Groothoff JW, Verlaak R, Strain L, Goodship THJ, Weening JJ, Davin JC, Atypical relapse of hemolytic uremic syndrome after transplantation. PEDIATR NEPHROL 2004;19 (10):1173-1176 [PubMed]
  • Rijneveld AW, Weijer S, Florquin S, Esmon CT, Meijers JCM, Speelman P, Reitsma PH, ten Cate H, van der Poll T, Thrombomodulin mutant mice with a strongly reduced capacity to generate activated protein C have an unaltered pulmonary immune response to respiratory pathogens and lipopolysaccharide. BLOOD 2004;103 (5):1702-1709 [PubMed]
  • Rijneveld AW, Weijer S, Florquin S, Speelman P, Shimizu T, Ishii S, van der Poll T, Improved host defense against pneumococcal pneumonia in platelet-activating factor receptor-deficient mice. J INFECT DIS 2004;189 (4):711-716 [PubMed]
  • Rouschop KMA, Sewnath ME, Claessen N, Roelofs JJTH, Hoedemaeker I, van der Neut R, Aten J, Pals ST, Weening JJ, Florquin S, CD44 deficiency increases tubular damage but reduces renal fibrosis in obstructive nephropathy. J AM SOC NEPHROL 2004;15 (3):674-686 [PubMed]
  • Rowshani AT, Florquin S, Bemelman F, Kummer JA, Hack CE, ten Berge IJM, Hyperexpression of the granzyme B inhibitor PI-9 in human renal allografts: A potential mechanism for stable renal function in patients with subclinical rejection. KIDNEY INT 2004;66 (4):1417-1422 [PubMed]
  • Schoenmakers SHHF, Groot AP, Florquin S, Reitsma PH, Spek CA, Blood cell-derived tissue factor influences host response during murine endotoxemia. BLOOD CELL MOL DIS 2004;32 (2):325-333 [PubMed]
  • van den Berg JG, van den Bergh Weerman MA, Assmann KJM, Weening JJ, Florquin S, Podocyte foot process effacement is not correlated with the level of proteinuria in human glomerulopathies. KIDNEY INT 2004;66 (5):1901-1906 [PubMed]
  • van der Sluijs KF, van Elden LJR, Nijhuis M, Schuurman R, Pater JM, Florquin S, Goldman M, Jansen HM, Lutter R, van der Poll T, IL-10 is an important mediator of the enhanced susceptibility to pneumococcal pneumonia after influenza infection. J IMMUNOL 2004;172 (12):7603-7609 [PubMed]
  • van Westerloo DJ, Schultz MJ, Bruno MJ, de Vos AF, Florquin S, van der Poll T, Acute pancreatitis in mice impairs bacterial clearance from the lungs, whereas concurrent pneumonia prolongs the course of pancreatitis. CRIT CARE MED 2004;32 (10):1997-2001 [PubMed]
  • Weijer S, Schoenmakers SHHF, Florquin S, Levi M, Vlasuk GP, Rote WE, Reitsma PH, Spek CA, van der Poll T, Inhibition of the tissue factor/factor VIIa pathway does not influence the inflammatory or antibacterial response to abdominal sepsis induced by Escherichia coli in mice. J INFECT DIS 2004;189 (12):2308-2317 [PubMed]
  • Wieland CW, Knapp S, Florquin S, de Vos AF, Takeda K, Akira S, Golenbock DT, Verbon A, van der Poll T, Non-mannose-capped lipoarabinomannan induces lung inflammation via toll-like receptor 2. AM J RESP CRIT CARE 2004;170 (12):1367-1374 [PubMed]

2003

  • Dörffler-Melly J, de Kruif M, Schwarte LA, Franco RF, Florquin S, Spek CA, Ince C, Reitsma PH, ten Cate H, Functional thrombomodulin deficiency causes enhanced thrombus growth in a murine model of carotid artery thrombosis. BASIC RES CARDIOL 2003;98 (6):347-352 [PubMed]
  • Florquin S, Rouschop KMA, Reciprocal functions of hepatocyte growth factor and transforming growth factor-beta1 in the progression of renal diseases: a role for CD44?. KIDNEY INT 2003;64 (Suppl. 86):S15-S20 [PubMed]
  • Knapp S, de Vos AF, Florquin S, Golenbock DT, van der Poll T, Lipopolysaccharide binding protein is an essential component of the innate immune response to Escherichia coli peritonitis in mice. INFECT IMMUN 2003;71 (12):6747-6753 [PubMed]
  • Knapp S, Leemans JC, Florquin S, Branger J, Maris NA, Pater J, van Rooijen N, van der Poll T, Alveolar macrophages have a protective antiinflammatory role during murine pneumococcal pneumonia. AM J RESP CRIT CARE 2003;167 (2):171-179 [PubMed]
  • Leemans JC, Florquin S, Heikens M, Pals ST, van der Neut R, van der Poll T, CD44 is a macrophage binding site for Mycobacterium tuberculosis that mediates macrophage recruitment and protective immunity against tuberculosis. J CLIN INVEST 2003;111 (5):681-689 [PubMed]
  • Leemans JC, Heikens M, van Kessel KPM, Florquin S, van der Poll T, Lipoteichoic acid and peptidoglycan from Staphylococcus aureus synergistically induce neutrophil influx into the lungs of mice. CLIN DIAGN LAB IMMUN 2003;10 (5):950-953 [PubMed]
  • Levi M, Dörffler-Melly J, Reitsma P, Buller H, Florquin S, van der Poll T, Carmeliet P, Aggravation of endotoxin-induced disseminated intravascular coagulation and cytokine activation in heterozygous protein-C-deficient mice. BLOOD 2003;101 (12):4823-4827 [PubMed]
  • Meijer RT, Surachno S, Yong SL, Bemelman FJ, Florquin S, ten Berge IJM, Schellekens PTA, Treatment of acute kidney allograft rejection with a non-mitogenic CD3 antibody. CLIN EXP IMMUNOL 2003;133 (3):485-492 [PubMed]
  • Rijneveld AW, Florquin S, Bresser P, Levi M, de Waard V, Lijnen R, van der Zee JS, Speelman P, Carmeliet P, van der Poll T, Plasminogen activator inhibitor type-1 deficiency does not influence the outcome of murine pneumococcal pneumonia. BLOOD 2003;102 (3):934-939 [PubMed]
  • Rijneveld AW, Florquin S, Hartung T, Speelman P, van der Poll T, Anti-tumor necrosis factor antibody impairs the therapeutic effect of ceftriaxone in murine pneumococcal pneumonia. J INFECT DIS 2003;188 (2):282-285 [PubMed]
  • Rijneveld AW, Florquin S, Speelman P, Edwards CK, Dinarello CA, van der Poll T, Interleukin-1 receptor antagonist transiently impairs antibacterial defense but not survival in murine pneumococcal pneumonia. EUR CYTOKINE NETW 2003;14 (4):242-245 [PubMed]
  • Roelofs JJTH, Rowshani AT, van den Berg JG, Claessen N, Aten J, ten Berge IJM, Weening JJ, Florquin S, Expression of urokinase plasminogen activator and its receptor during acute renal allograft rejection. KIDNEY INT 2003;64 (5):1845-1853 [PubMed]
  • Schultz MJ, Knapp S, Florquin S, Pater J, Takeda K, Akira S, van der Poll T, Interleukin-18 impairs the pulmonary host response to Pseudomonas aeruginosa. INFECT IMMUN 2003;71 (4):1630-1634 [PubMed]
  • van der Sluijs KF, van Elden L, Nijhuis M, Schuurman R, Florquin S, Jansen HM, Lutter R, van der Poll T, Toll-like receptor 4 is not involved in host defense against respiratory tract infection with Sendai virus. IMMUNOL LETT 2003;89 (2-3):201-206 [PubMed]
  • Weijer S, Leemans JC, Florquin S, Shimizu T, Ishii S, van der Poll T, Host response of platelet-activating factor receptor-deficient mice during pulmonary tuberculosis. IMMUNOLOGY 2003;109 (4):552-556 [PubMed]
  • Weijer S, Sewnath ME, de Vos AF, Florquin S, van der Sluis K, Gouma DJ, Takeda K, Akira S, van der Poll T, Interleukin-18 facilitates the early antimicrobial host response to Escherichia coli peritonitis. INFECT IMMUN 2003;71 (10):5488-5497 [PubMed]
  • Zwijnenburg PJG, Polfliet MMJ, Florquin S, van den Berg TK, Dijkstra CD, van Deventer SJH, Roord JJ, van der Poll T, van Furth AM, CXC-chemokines KC and macrophage inflammatory protein-2 (MIP-2) synergistically induce leukocyte recruitment to the central nervous system in rats. IMMUNOL LETT 2003;85 (1):1-4 [PubMed]
  • Zwijnenburg PJG, van der Poll T, Florquin S, Akira S, Takeda K, Roord JJ, van Furth AM, Interleukin-18 gene-deficient mice show enhanced defense and reduced inflammation during pneumococcal meningitis. J NEUROIMMUNOL 2003;138 (1-2):31-37 [PubMed]
  • Zwijnenburg PJG, van der Poll T, Florquin S, Roord JJ, van Furth AM, IL-1 receptor type 1 gene-deficient mice demonstrate an impaired host defense against pneumococcal meningitis. J IMMUNOL 2003;170 (9):4724-4730 [PubMed]
  • Zwijnenburg PJG, van der Poll T, Florquin S, Roord JJ, van Furth AM, Interleukin-10 negatively regulates local cytokine and chemokine production but does not influence antibacterial host defense during murine pneumococcal meningitis. INFECT IMMUN 2003;71 (4):2276-2279 [PubMed]

2002

  • Florquin S, Nunziata R, Claessen N, van den Berg FM , Pals ST, Weening JJ, CD44 expression in IgA nephropathy. AM J KIDNEY DIS 2002;39 (2):407-414 [PubMed]
  • Juffermans NP, Leemans JC, Florquin S, Verbon A, Kolk AH, Speelman P, van Deventer SJH, van der Poll T, CpG oligodeoxynucleotides enhance host defense during murine tuberculosis. INFECT IMMUN 2002;70 (1):147-152 [PubMed]
  • Lauw FN, Branger J, Florquin S, Speelman P, van Deventer SJH, Akira S, van der Poll T, IL-18 improves the early antimicrobial host response to pneumococcal pneumonia. J IMMUNOL 2002;168 (1):372-378 [PubMed]
  • Leemans JC, Vervoordeldonk MJBM, Florquin S, van Kessel KP, van der Poll T, Differential role of interleukin-6 in lung inflammation induced by lipoteichoic acid and peptidoglycan from Staphylococcus aureus. AM J RESP CRIT CARE 2002;165 (10):1445-1450 [PubMed]
  • Lettinga KD, Florquin S, Speelman P, van Ketel R, van der Poll T, Verbon A, Toll-like receptor 4 is not involved in host defense against pulmonary Legionella pneumophila infection in a mouse model. J INFECT DIS 2002;186 (4):570-573 [PubMed]
  • Rijneveld AW, Lauw FN, Schultz MJ, Florquin S, te Velde AA, Speelman P, van Deventer SJH, van der Poll T, The role of interferon-gamma in murine pneumococcal pneumonia. J INFECT DIS 2002;185 (1):91-97 [PubMed]
  • Rijneveld AW, Levi M, Florquin S, Speelman P, Carmeliet P, van der Poll T, Urokinase receptor is necessary for adequate host defense against pneumococcal pneumonia. J IMMUNOL 2002;168 (7):3507-3511 [PubMed]
  • Rijneveld AW, van den Dobbelsteen GP, Florquin S, Standiford TJ, Speelman P, van Alphen L, van der Poll T, Roles of interleukin-6 and macrophage inflammatory protein-2 in pneumolysin-induced lung inflammation in mice. J INFECT DIS 2002;185 (1):123-126 [PubMed]
  • Schultz MJ, Rijneveld AW, Florquin S, Edwards CK, Dinarello CA, van der Poll T, Role of interleukin-1 in the pulmonary immune response during Pseudomonas aeruginosa pneumonia. AM J PHYSIOL-LUNG C 2002;282 (2):L285-L290 [PubMed]
  • Verbon A, Leemans JC, Weijer S, Florquin S, van der Poll T, Mice lacking the multidrug resistance protein 1 have a transiently impaired immune response during tuberculosis. CLIN EXP IMMUNOL 2002;130 (1):32-36 [PubMed]

2001

  • Florquin S, Roos A, Groothoff JW, Claessen N, van Gijlswijk-Janssen DJ, Aten J, Davin JC, Weening JJ, Severe non-proliferative lupus nephritis with predominant sub-endothelial IgA deposits. NEPHROL DIAL TRANSPL 2001;16 (7):1479-1482 [PubMed]
  • Florquin S, van den Berg JG, Olszyna DP, Claessen N, Opal SM, Weening JJ, van der Poll T, Release of urokinase plasminogen activator receptor during urosepsis and endotoxemia. KIDNEY INT 2001;59 (6):2054-2061 [PubMed]
  • Langermans JA, Andersen P, van Soolingen D, Vervenne RA, Frost PA, van der Laan T, van Pinxteren LA, van den Hombergh J, Kroon S, Peekel I, Florquin S, Thomas AW, Divergent effect of bacillus Calmette-Guérin (BCG) vaccination on Mycobacterium tuberculosis infection in highly related macaque species: implications for primate models in tuberculosis vaccine research. P NATL ACAD SCI USA 2001;98 (20):11497-11502 [PubMed]
  • Lauw FN, Florquin S, Speelman P, van Deventer SJ, van der Poll T, Role of endogenous interleukin-12 in immune response to staphylococcal enterotoxin B in mice. INFECT IMMUN 2001;69 (9):5949-5952 [PubMed]
  • Leemans JC, Juffermans NP, Florquin S, van Rooijen N, Vervoordeldonk MJ, Verbon A, van Deventer SJ, van der Poll T, Depletion of alveolar macrophages exerts protective effects in pulmonary tuberculosis in mice. J IMMUNOL 2001;166 (7):4604-4611 [PubMed]
  • Noël C, Florquin S, Goldman M, Braun MY, Chronic exposure to superantigen induces regulatory CD4(+) T cells with IL-10-mediated suppressive activity. INT IMMUNOL 2001;13 (4):431-439 [PubMed]
  • Olszyna DP, Florquin S, Sewnath M, Branger J, Speelman P, van Deventer SJ, Strieter RM, van der Poll T, CXC chemokine receptor 2 contributes to host defense in murine urinary tract infection. J INFECT DIS 2001;184 (3):301-307 [PubMed]
  • Rijneveld AW, Florquin S, Branger J, Speelman P, van Deventer SJ, van der Poll T, TNF-alpha compensates for the impaired host defense of IL-1 type I receptor-deficient mice during pneumococcal pneumonia. J IMMUNOL 2001;167 (9):5240-5246 [PubMed]
  • Schultz MJ, Rijneveld AW, Florquin S, Speelman P, van Deventer SJ, van der Poll T, Impairment of host defence by exotoxin A in Pseudomonas aeruginosa pneumonia in mice. J MED MICROBIOL 2001;50 (9):822-827 [PubMed]
  • Zwijnenburg PJ, van der Poll T, Florquin S, van Deventer SJ, Roord JJ, van Furth AM, Experimental pneumococcal meningitis in mice: a model of intranasal infection. J INFECT DIS 2001;183 (7):1143-1146 [PubMed]

2000

  • Juffermans NP, Florquin S, Camoglio L, Verbon A, Kolk AH, Speelman P, van Deventer SJ, van der Poll T, Interleukin-1 signaling is essential for host defense during murine pulmonary tuberculosis. J INFECT DIS 2000;182 (3):902-908 [PubMed]
  • van Velthuysen ML, Florquin S, Glomerulopathy associated with parasitic infections. CLIN MICROBIOL REV 2000;13 (1):55-66, table of contents [PubMed]

1999

  • de Heer E, Aaldering L, Florquin S, T cell subsets in experimental lupus nephritis: modulation by bacterial superantigen. NEPHROL DIAL TRANSPL 1999;14 (Suppl. 1):14-16 [PubMed]
  • Delaunois A, Florquin S, Segura P, Montano LM, Vargas MH, Gustin P, Interactions between cytochrome P-450 activities and ozone-induced modulatory effects on endothelial permeability in rabbit lungs: influence of gender. INHAL TOXICOL 1999;11 (11):999-1014 [PubMed]

1997

  • Florquin S, Aaldering L, Superantigens: a tool to gain new insight into cellular immunity. RES IMMUNOL 1997;148 (6):373-386 [PubMed]

1996

  • Florquin S, Amraoui Z, Goldman M, Persistent production of TH2-type cytokines and polyclonal B cell activation after chronic administration of staphylococcal enterotoxin B in mice. J AUTOIMMUN 1996;9 (5):609-615 [PubMed]
  • Florquin S, Goldman M, Immunoregulatory mechanisms of T-cell-dependent shock induced by a bacterial superantigen in mice. INFECT IMMUN 1996;64 (9):3443-3445 [PubMed]

1995

  • Florquin S, Amraoui Z, Goldman M, T cells made deficient in interleukin-2 production by exposure to staphylococcal enterotoxin B in vivo are primed for interferon-gamma and interleukin-10 secretion. EUR J IMMUNOL 1995;25 (5):1148-1153 [PubMed]

1994

  • Delvaux A, Donckier V, Bruyns C, Florquin S, Gérard C, Amraoui Z, Abramowicz D, Goldman M, Velu T, Effects of systemic administration of rIL-10 in an in vivo model of alloreactivity. TRANSPLANTATION 1994;58 (8):972-974 [PubMed]
  • Donckier V, Abramowicz D, Bruyns C, Florquin S, Vanderhaeghen ML, Amraoui Z, Dubois C, Vandenabeele P, Goldman M, IFN-gamma prevents Th2 cell-mediated pathology after neonatal injection of semiallogenic spleen cells in mice. J IMMUNOL 1994;153 (6):2361-2368 [PubMed]
  • Florquin S, Amraoui Z, Abramowicz D, Goldman M, Systemic release and protective role of IL-10 in staphylococcal enterotoxin B-induced shock in mice. J IMMUNOL 1994;153 (6):2618-2623 [PubMed]
  • Florquin S, Amraoui Z, Dubois C, Decuyper J, Goldman M, The protective role of endogenously synthesized nitric oxide in staphylococcal enterotoxin B-induced shock in mice. J EXP MED 1994;180 (3):1153-1158 [PubMed]
  • Florquin S, Goldman M, T cell subsets in glomerular diseases. SPRINGER SEMIN IMMUN 1994;16 (1):71-80 [PubMed]
  • Goldman M, Marchant A, Florquin S, Velu T, Rôle de l'interleukine-10 dans la régulation des résponses immunes en pathologie infectieuse. REV MED BRUX 1994;15 (2):61-65 [PubMed]

1993

  • Bloom RD, Florquin S, Singer GG, Brennan DC, Kelley VR, Colony stimulating factor-1 in the induction of lupus nephritis. KIDNEY INT 1993;43 (5):1000-1009 [PubMed]

1992

  • Abramowicz D, Pradier O, Marchant A, Florquin S, de Pauw L, Vereerstraeten P, Kinnaert P, Vanherweghem JL, Goldman M, Induction of thromboses within renal grafts by high-dose prophylactic OKT3. LANCET 1992;339 (8796):777-778 [PubMed]
  • Díaz Gallo C, Jevnikar AM, Brennan DC, Florquin S, Pacheco-Silva A, Kelley VR, Autoreactive kidney-infiltrating T-cell clones in murine lupus nephritis. KIDNEY INT 1992;42 (4):851-859 [PubMed]
  • Doutrelepont JM, Abramowicz D, Florquin S, de Pauw L, Goldman M, Kinnaert P, Vereerstraeten P, Early recurrence of hemolytic uremic syndrome in a renal transplant recipient during prophylactic OKT3 therapy. TRANSPLANTATION 1992;53 (6):1378-1379 [PubMed]
  • Jacobs F, Byl B, Bourgeois N, Coremans-Pelseneer J, Florquin S, Depré G, van de Stadt J, Adler M, Gelin M, Thys JP, Trichoderma viride infection in a liver transplant recipient. MYCOSES 1992;35 (11-12):301-303 [PubMed]

1991

  • Alegre ML, Depierreux M, Florquin S, Abramowicz D, de Pauw L, Kinnaert P, Vereerstraeten P, Goldman M, Néphrotoxicité des anticorps monoclonaux anti-CD3. NEPHROLOGIE 1991;12 (1):42-45 [PubMed]
  • Alegre ML, Vandenabeele P, Depierreux M, Florquin S, Deschodt-Lanckman M, Flamand V, Moser M, Leo O, Urbain J, Fiers W, Cytokine release syndrome induced by the 145-2C11 anti-CD3 monoclonal antibody in mice: prevention by high doses of methylprednisolone. J IMMUNOL 1991;146 (4):1184-1191 [PubMed]
  • Florquin S, Abramowicz D, de Heer E, Bruijn JA, Doutrelepont JM, Goldman M, Hoedemaeker P, Renal immunopathology in murine host-versus-graft disease. KIDNEY INT 1991;40 (5):852-861 [PubMed]

1990

  • Alegre M, Depierreux M, Florquin S, Najdovski T, Vandenabeele P, Abramowicz D, Leo O, Deschodt-Lanckman M, Goldman M, Acute toxicity of anti-CD3 monoclonal antibody in mice: a model for OKT3 first dose reactions. TRANSPL P 1990;22 (4):1920-1921 [PubMed]