S.L. Yong publications


Publications S.L. Yong

Laboratory technician
Main activities
Focus of research

Kidney transplantation Immunology


  • van den Heuvel H, Heutinck KM, van der Meer-Prins EMW, Yong SL, van Miert PPMC, Anholts JDH, Franke-van Dijk MEI, Zhang XQ, Roelen DL, ten Berge RJM, Claas FHJ, Allo-HLA Cross-Reactivities of Cytomegalovirus-, Influenza-, and Varicella Zoster Virus-Specific Memory T Cells Are Shared by Different Healthy Individuals. AM J TRANSPLANT 2017;17 (8):2033-2044 [PubMed]


  • Heutinck KM, Yong SL, Tonneijck L, van den Heuvel H, van der Weerd NC, van der Pant KAMI, Bemelman FJ, Claas FHJ, ten Berge IJM, Virus-Specific CD8(+) T Cells Cross-Reactive to Donor-Alloantigen Are Transiently Present in the Circulation of Kidney Transplant Recipients Infected With CMV and/or EBV. AM J TRANSPLANT 2016;16 (5):1480-1491 [PubMed]


  • Havenith SHC, Remmerswaal EBM, Bemelman FJ, Yong SL, van Donselaar-van der Pant KAMI, van Lier RAW, ten Berge IJM, Rapid T cell repopulation after rabbit anti-thymocyte globulin (rATG) treatment is driven mainly by cytomegalovirus. CLIN EXP IMMUNOL 2012;169 (3):292-301 [PubMed]
  • van de Berg PJEJ, Hoevenaars EC, Yong SL, van Donselaar-van der Pant KAMI, van Tellingen A, Florquin S, van Lier RAW, Bemelman FJ, ten Berge IJM, Circulating lymphocyte subsets in different clinical situations after renal transplantation. IMMUNOLOGY 2012;136 (2):198-207 [PubMed]
  • van de Berg PJEJ, Yong SL, Koch SD, Lardy N, van Donselaar-van der Pant KAMI, Florquin S, Bemelman FJ, van Lier RAW, ten Berge IJM, Characteristics of alloreactive T cells measured before renal transplantation. CLIN EXP IMMUNOL 2012;168 (2):241-250 [PubMed]
  • van de Berg PJEJ, Yong SL, Remmerswaal EBM, van Lier RAW, ten Berge IJM, Cytomegalovirus-Induced Effector T Cells Cause Endothelial Cell Damage. CLIN VACCINE IMMUNOL 2012;19 (5):772-779 [PubMed]


  • Hertoghs KML, Moerland PD, van Stijn A, Remmerswaal EBM, Yong SL, van de Berg PJEJ, van Ham SM, Baas F, ten Berge IJM, van Lier RAW, Molecular profiling of cytomegalovirus-induced human CD8+ T cell differentiation. J CLIN INVEST 2010;120 (11):4077-4090 [PubMed]
  • van de Berg PJEJ, Griffiths SJ, Yong SL, Macaulay R, Bemelman FJ, Jackson S, Henson SM, ten Berge IJM, Akbar AN, van Lier RAW, Cytomegalovirus Infection Reduces Telomere Length of the Circulating T Cell Pool. J IMMUNOL 2010;184 (7):3417-3423 [PubMed]


  • Nikolaeva N, Bemelman FJ, Yong SL, Verschuur A, van Lier RAW, ten Berge IJM, The pyrimidin analogue cyclopentenyl cytosine induces alloantigen-specific non-responsiveness of human T lymphocytes. CLIN EXP IMMUNOL 2008;151 (2):348-358 [PubMed]
  • Sankatsing SUC, Prins JM, Yong SLL, Roelofsen J, van Kuilenburg ABP, Kewn S, Back DJ, Bemelman FJ, ten Berge IJM, Mycophenolate mofetil inhibits T-cell proliferation in kidney transplant recipients without lowering intracellular dGTP and GTP. TRANSPL INT 2008;21 (11):1066-1071 [PubMed]
  • van Stijn A, Rowshani AT, Yong SL, Baas F, Roosnek E, ten Berge IJM, van Lier RAW, Human cytomegalovirus infection induces a rapid and sustained change in the expression of NK cell receptors on CD8+ T cells. J IMMUNOL 2008;180 (7):4550-4560 [PubMed]


  • Uss E, Yong SL, Hooibrink B, van Lier RAW, ten Berge IJM, Rapamycin enhances the number of alloantigen-induced human CD103+CD8+ regulatory T cells in vitro. TRANSPLANTATION 2007;83 (8):1098-1106 [PubMed]


  • Nikolaeva N, Bemelman FJ, Yong SL, van Lier RAW, ten Berge IJM, Rapamycin does not induce anergy but inhibits expansion and differentiation of alloreactive human T cells. TRANSPLANTATION 2006;81 (3):445-454 [PubMed]


  • Bemelman F, Yong SL, Tissingh R, Schellekens P, ten Berge I, Suppression extends to major histocompatibility antigens linked to tolerizing minor histocompatibility antigens, but not the other way round. TRANSPL INT 2005;18 (4):423-428 [PubMed]
  • Rowshani AT, Strik MCM, Molenaar R, Yong SL, Wolbink AM, Bemelman FJ, Hack CE, ten Berge IJM, The granzyme B inhibitor SERPINB9 (protease inhibitor 9) circulates in blood and increases on primary cytomegalovirus infection after renal transplantation. J INFECT DIS 2005;192 (11):1908-1911 [PubMed]
  • van Leeuwen EMM, de Bree GJ, Remmerswaal EBM, Yong SL, Tesselaar K, ten Berge IJM, van Lier RAW, IL-7 receptor alpha chain expression distinguishes functional subsets of virus-specific human CD8+ T cells. BLOOD 2005;106 (6):2091-2098 [PubMed]


  • Gamadia LE, van Leeuwen EMM, Remmerswaal EBM, Yong SL, Surachno S, Wertheim-van Dillen PME, ten Berge IJM, van Lier RAW, The size and phenotype of virus-specific T cell populations is determined by repetitive antigenic stimulation and environmental cytokines. J IMMUNOL 2004;172 (10):6107-6114 [PubMed]
  • Rowshani AT, Uss A, Yong SL, van Lier RAW, ten Berge IJM, Effects of CD25 monoclonal antibody on proliferative and effector functions of alloactivated human T cells in vitro. EUR J IMMUNOL 2004;34 (3):882-899 [PubMed]


  • Meijer RT, Surachno S, Yong SL, Bemelman FJ, Florquin S, ten Berge IJM, Schellekens PTA, Treatment of acute kidney allograft rejection with a non-mitogenic CD3 antibody. CLIN EXP IMMUNOL 2003;133 (3):485-492 [PubMed]


  • Bemelman FJ, Yong S, Parlevliet KJ, Surachno S, Schellekens PTA, ten Berge RJM, No long-term benefit of low-dose OKT3 induction therapy in non to moderately immunized renal allograft recipients. TRANSPL P 2002;34 (8):3165-3167 [PubMed]


  • Meijer RT, Yong SL, Surachno S, ten Berge IJ, Schellekens PT, Treatment of acute kidney allograft rejection with the nonmitogenic CD3 mAb CLB T3/4.A (IgA-CD3): absence of a correlation of clinical responsiveness with inhibition of lymphocyte reactivity in vitro. TRANSPL P 2001;33 (1-2):1229-1230 [PubMed]
  • Meijer RT, Yong SL, ten Berge IJ, van Lier RA, Schellekens PT, Non FcR-binding murine antihuman CD3 monoclonal antibody is capable of productive TCR signalling and induces proliferation in the presence of costimulation. CLIN EXP IMMUNOL 2001;123 (3):511-519 [PubMed]
  • van Praag RM, Prins JM, Roos MT, Schellekens PT, ten Berge IJ, Yong SL, Schuitemaker H, Eerenberg AJ, Jurriaans S, de Wolf F, Fox CH, Goudsmit J, Miedema F, Lange JM, OKT3 and IL-2 treatment for purging of the latent HIV-1 reservoir in vivo results in selective long-lasting CD4+ T cell depletion. J CLIN IMMUNOL 2001;21 (3):218-226 [PubMed]


  • Enomoto DN, Mekkes JR, Bossuyt PM, Yong SL, Out TA, Hoekzema R, de Rie MA, Schellekens PT, ten Berge IJ, de Borgie CA, Bos JD, Treatment of patients with systemic sclerosis with extracorporeal photochemotherapy (photopheresis). J AM ACAD DERMATOL 1999;41 (6):915-922 [PubMed]
  • Prins JM, Jurriaans S, van Praag RM, Blaak H, van Rij R, Schellekens PT, ten Berge IJ, Yong SL, Fox CH, Roos MT, de Wolf F, Goudsmit J, Schuitemaker H, Lange JM, Immuno-activation with anti-CD3 and recombinant human IL-2 in HIV-1-infected patients on potent antiretroviral therapy. AIDS 1999;13 (17):2405-2410 [PubMed]


  • Enomoto DN, Schellekens PT, Yong SL, ten Berge IJ, Mekkes JR, Bos JD, Extracorporeal photochemotherapy (photopheresis) induces apoptosis in lymphocytes: a possible mechanism of action of PUVA therapy. PHOTOCHEM PHOTOBIOL 1997;65 (1):177-180 [PubMed]
  • Stronkhorst A, Radema S, Yong SL, Bijl H, ten Berge IJ, Tytgat GN, van Deventer SJ, CD4 antibody treatment in patients with active Crohn's disease: a phase 1 dose finding study. GUT 1997;40 (3):320-327 [PubMed]
  • van der Vliet HJ, Wever PC, van Diepen FN, Yong SL, ten Berge IJ, Quantification of Bax/Bcl-2 ratios in peripheral blood lymphocytes, monocytes and granulocytes and their relation to susceptibility to anti-Fas (anti-CD95)-induced apoptosis. CLIN EXP IMMUNOL 1997;110 (2):324-328 [PubMed]


  • Bemelman FJ, Buysmann S, Yong SL, van Diepen FN, Schellekens PT, ten Berge RJ, Biphasic granulocytopenia after administration of the first dose of OKT3. J LAB CLIN MED 1995;126 (6):571-579 [PubMed]
  • Buysmann S, van Diepen FN, Yong SL, Surachno S, Schellekens PT, ten Berge RJ, Mechanism of lymphocytopenia following administration of corticosteroids. TRANSPL P 1995;27 (1):871-872 [PubMed]
  • Parlevliet KJ, Bemelman FJ, Yong SL, Hack CE, Surachno J, Wilmink JM, ten Berge IJ, Schellekens PT, Toxicity of OKT3 increases with dosage: a controlled study in renal transplant recipients. TRANSPL INT 1995;8 (2):141-146 [PubMed]
  • Parlevliet KJ, Chamuleau ME, Yong SL, Raasveld MH, ten Berge IJ, Schellekens PT, Effects of anti-CD3 monoclonal antibodies on functional activity of lymphocytes: studies in vivo and in vitro. CLIN EXP IMMUNOL 1995;99 (2):155-159 [PubMed]


  • Parlevliet KJ, ten Berge IJ, Yong SL, Surachno J, Wilmink JM, Schellekens PT, In vivo effects of IgA and IgG2a anti-CD3 isotype switch variants. J CLIN INVEST 1994;93 (6):2519-2525 [PubMed]
  • ten Berge IJ, Parlevliet KJ, Yong SL, Surachno J, Wilmink JM, Schellekens PT, Toxicity of IgA anti-CD3 isotype switch variant in vivo. TRANSPL P 1994;26 (6):3150 [PubMed]


  • Rambukkana A, Das PK, Burggraaf JD, Yong S, Faber WR, Thole JE, Harboe M, Heterogeneity of monoclonal antibody-reactive epitopes on mycobacterial 30-kilodalton-region proteins and the secreted antigen 85 complex and demonstration of antigen 85B on the Mycobacterium leprae cell wall surface. INFECT IMMUN 1992;60 (12):5172-5181 [PubMed]
  • van der Werf TS, Das PK, van Soolingen D, Yong S, van der Mark TW, van den Akker R, Sero-diagnosis of tuberculosis with A60 antigen enzyme-linked immunosorbent assay: failure in HIV-infected individuals in Ghana. MED MICROBIOL IMMUN 1992;181 (2):71-76 [PubMed]


  • van der Werf TS, Koëter GH, Das PK, Yong S, Monoclonal ELISA to detect active tuberculosis. LANCET 1990;336 (8729):1516 [PubMed]


  • Bloemena E, van Oers MH, Weinreich S, Yong SL, Schellekens PT, Cyclosporine A does not prevent expression of biologically active IL 2 receptors in vitro. TRANSPL P 1988;20 (2 Suppl 2):131-135 [PubMed]
  • Bloemena E, van Oers MH, Weinreich S, Yong SL, Schellekens PT, Prednisolone and cyclosporin A exert differential inhibitory effects on T-cell proliferation in vitro. CLIN IMMUNOL IMMUNOPATHOL 1988;48 (3):380-391 [PubMed]
  • van der Heyden AA, van Oers MH, Cornelissen P, Yong SL, Wilmink JM, Schellekens PT, The influence of cyclosporine A treatment on immune responsiveness in vitro and in vivo in kidney transplant recipients. TRANSPL P 1988;20 (2 Suppl 2):190-195 [PubMed]


  • ten Berge RJ, Sauerwein HP, Yong SL, Schellekens PT, Administration of prednisolone in vivo affects the ratio of OKT4/OKT8 and the LDH-isoenzyme pattern of human T lymphocytes. CLIN IMMUNOL IMMUNOPATHOL 1984;30 (1):91-103 [PubMed]