MD PhD J. Fraessdorf


MD PhD J. Fraessdorf

Medical Specialist
Main activities
Patient care, Other
Emergency care, MedEvac, cardiac anesthesiology, Hyperbaric medicine, loco-regional anesthesia,
Focus of research

myocardial protection, preconditioning, postconditioning, mechanisms of anesthetic induced tissue protection

Key publications
  • Frässdorf Jan, Borowski Andreas, Ebel Dirk, Feindt Peter, Hermes Manuel, Meemann Thomas, Weber René, Müllenheim Jost, Weber Nina C., Preckel Benedikt, Schlack Wolfgang Impact of preconditioning protocol on anesthetic-induced cardioprotection in patients having coronary artery bypass surgery Journal of thoracic and cardiovascular surgery 2009;137 (6):1436-42, 1442.e1-2 [PubMed]
  • Fräßdorf Jan, Huhn Ragnar, Niersmann Corinna, Weber Nina C., Schlack Wolfgang, Preckel Benedikt, Hollmann Markus W. Morphine induces preconditioning via activation of mitochondrial K(Ca) channels La morphine provoque le préconditionnement par l'activation des canaux mitochondriaux K(Ca) Canadian journal of anaesthesia = Journal canadien d'anesthésie 2010;57 (8):767-773 [PubMed]
  • Fräßdorf Jan, Huhn Ragnar, Weber Nina C., Ebel Dirk, Wingert Nadja, Preckel Benedikt, Toma Octavian, Schlack Wolfgang, Hollmann Markus W. Sevoflurane-induced Preconditioning Impact of Protocol and Aprotinin Administration on Infarct Size and Endothelial Nitric-Oxide Synthase Phosphorylation in the Rat Heart In Vivo Anesthesiology 2010;113 (6):1289-1298 [PubMed]
  • Fräßdorf J., de Hert S., Schlack W. Anaesthesia and myocardial ischaemia/reperfusion injury British journal of anaesthesia 2009;103 (1):89-98 [PubMed]
  • Frässdorf Jan, Weber Nina C., Obal Detlef, Toma Octavian, Müllenheim Jost, Kojda Georg, Preckel Benedikt, Schlack Wolfgang Morphine induces late cardioprotection in rat hearts in vivo: the involvement of opioid receptors and nuclear transcription factor kappaB Anesthesia and analgesia 2005;101 (4):934-41, table of contents [PubMed]
All Publications
Research programmes

Prof. MD PhD M.W. Hollmann (Organprotection)

Prof. MA MD PhD B. Preckel (Patient safety, procedural sedation, cardiovascular protection, optimizing perioperative metabolism, cerebral perfusion, Wireless Monitoring)