PhD M.A. Brehm

foto

PhD M.A. Brehm

Position
Research Associate
Main activities
Research, Other
Specialisation
gait studies in neurmuscular disorders and cerebral palsy
Focus of research

Research focuses on functioning of patients with neuromuscular diseases (postpoliomyelitis syndrome (PPS)) and children with cerebral palsy (CP), including intervention studies on lower limb orthoses. Other areas of focus include reliability research on walking energy expenditure measures and on aerobic and anaerobic fitness testing.

Key publications
  • Brehm Merel-Anne, Harlaar Jaap, Schwartz Michael Effect of ankle-foot orthoses on walking efficiency and gait in children with cerebral palsy Journal of rehabilitation medicine 2008;40 (7):529-534 [PubMed]
  • Kempen J. C. E., Harlaar J., van der Kooi A. J., de Groot I. J. M., van den Bergen J. C., Niks E. H., Verschuuren J. J. G. M., Brehm M. A. Reliability of the walking energy cost test and the six-minute walk test in boys with Duchenne muscular dystrophy Neuromuscular disorders 2014;24 (3):216-221 [PubMed]
  • Kerkum Yvette L., Harlaar Jaap, Buizer Annemieke I., van den Noort Josien C., Becher Jules G., Brehm Merel-Anne An individual approach for optimizing ankle-foot orthoses to improve mobility in children with spastic cerebral palsy walking with excessive knee flexion Gait & posture 2016;46:104-111 [PubMed]
  • Kerkum Yvette L., Buizer Annemieke I., van den Noort Josien C., Becher Jules G., Harlaar Jaap, Brehm Merel-Anne The Effects of Varying Ankle Foot Orthosis Stiffness on Gait in Children with Spastic Cerebral Palsy Who Walk with Excessive Knee Flexion PLoS ONE 2015;10 (11):e0142878 [PubMed]
  • Brehm Merel-Anne, Kempen Jiska C. E., van der Kooi Anneke J., de Groot Imelda J. M., van den Bergen Janneke C., Verschuuren Jan J. G. M., Niks Erik H., Harlaar Jaap Age-related longitudinal changes in metabolic energy expenditure during walking in boys with Duchenne muscular dystrophy PLoS ONE 2014;9 (12):e115200 [PubMed]
All Publications
Curriculum Vitae

Personal Information

Name: Brehm
First name: Merel (female)
Birth date: 29/06/1976

Academic qualifications

  • Doctorate (PhD) in Human Movement Sciences; Faculty of Medicine, VU University Amsterdam, The Netherlands. 21/06/2007, Thesis title ‘The clinical assessment of energy expenditure in pathological gait'
  • Master's (MSc) in Human Movement Sciences; Faculty of Human Movement Sciences, VU University Amsterdam,  31/10/2001
  • Bachelor's in Occupational Therapy; Faculty of Occupational therapy, Hogeschool van Amsterdam, 31/01/1998

Employment history

  • 01/01/2010 – recent          0.87 fte/permanent appointment as senior iresearcher at the Department of Rehabilitation of the AMC
  • 15/07/2007 – 31/12/2009: 1.0 fte/fixed-term appointment as post-doc researcher at the Department of Rehabilitation Medicine of the VUmc
  • 01/04/2005 – 01/07/2005: 1.0 fte/stipendium appointment as PhD student at Gillette Children’s Speciality Healthcare, St Paul, USA
  • 01/11/2001 – 15/07/2007: 1.0 fte/fixed-term appointment as PhD student at the Department of Rehabilitation Medicine of the VUmc
  • 01/01/2001 – 01/01/2002: 0.2 fte/fixed-term appointment as assistant researcher at the Faculty of Human Movement Sciences, VU University
  • 01/04/2000 – 01/08/2000: 1.0 fte/fixed-term appointment as an occupational therapist at the Heliomare Rehabilitation Center, Wijk aan Zee.

 

 Grants, scholarships and prizes

  • 2005: Stipendium for a research internship (3-months) on the effects of ankle-foot orthoses in children with cerebral palsy at the Gillette Children’s Hospital in St Paul, USA. Principal applicant: Mrs. dr. M.A Brehm; The stipendium was granted by the KNAW Ter Meulen fonds. (€7.250, 1.0 fte)
  • 2007: Grant for a 2-year implementation project (‘Development of an orthotic guideline’) Principal applicant: Mrs. dr. M.A Brehm; collaborative applicants: Prof. dr. F. Nollet and Prof. dr. J. Dekker. The grant was subsidized by ZonMw (2e top down implementatieronde van het programma Revalidatieonderzoek. (€70.000, 0.5 fte)
  • 2009: Grant for a 2-year guideline project on orthotics. Principal applicant: Mrs. dr. M.A Brehm; collaborative applicant: Prof. dr. F. Nollet. The grant was subsidized by the SKMS (Stichting Kwaliteitsgelden Medisch Specialisten). (€68.000, 0.5 fte)
  • 2009: Grant for a 1-year innovation project (‘Development of a digital physical examination application’). Principal applicant: Mrs. dr. M.A Brehm; collaborative applicants: dr. ir. J. Harlaar and Mrs. Lia Out. The grant was subsidized by ZonMw (Innovatieprogramma Revalidatie). (€40.000)
  • 2010: Grant for a 4-year PhD-project on the effects of ankle-foot orthoses on mobility and participation in children cerebral palsy. Principal applicant: Mrs. dr. M.A Brehm; collaborative applicants: Prof J. Becher and dr. ir. J Harlaar. The grant was subsidized by the Phelps Stichting, the Johanna Kinderfonds, and the Adriaan Stichting. (€330.000)
  • 2010: Grant for a 1-year innovation project. Principal applicant: Mrs. dr. A. Dallmeijer; collaborative applicants: Mrs. dr. M.A Brehm, dr. ir. J. Harlaar, mrs. Dr. A Buizer and Mrs. Dr. P van Schie. The grant was subsidized by ZonMw (Innovatieprogramma Revalidatie). (€45.000)
  • 2014: Grant for a 1-year implementation project (FACTS-2-NMD+). Principal applicants: dr. M.A. Brehm and prof. dr. F Nollet. ZonMw subsidized the grant. (€30.000)
  • 2014: Grant for a 4-year PhD-project. Principal applicants: dr. M.A. Brehm and prof. dr. F Nollet. The grant was subsidized by the Prinses Beatrix Spierfonds. (€249.117)
  • 2015/2016: Grant for a 2-year research project. Principal applicant: dr. M.A. Brehm. The grant was subsidized by the Phelps stichting voor spastici and the Johanna Kinderfonds. (€120.000).

 Supervision of PhD students/co-promotor  

  • Mrs. Y.L. Kerkum. March 7 2016. Maximizing the efficacy of Ankle-Foot Orthoses in children with cerebral palsy; Promoters: Prof. dr. J.G. Becher and Prof. dr. ir.  J. Harlaar, co-promoters: dr. M.A. Brehm and dr. A.I. Buizer.
  • Mrs. S. Koopman. October 13 2016. Treating fatigue in post-polio syndrome; Promoters: Prof dr. F. Nollet and Prof. dr. M. de Visser, co-promoters: dr. J.A. Beelen and dr. M.A. Brehm
  • Mrs H.E. Ploeger. Start 2012. The application of dorsiflexion-stopped ankle foot orthoses in polio survivors with calf muscle weakness; Promoter: Prof dr. F. Nollet. co-promoters: dr. M.A. Brehm and dr. S.A. Bus.
  • Mr. N.F. Waterval. Start 2014. Precision orthotics: optimizing ankle foot orthoses to improve mobility in neuromuscular diseases. Promoters: Prof. dr. F Nollet and Prof. dr. ir.  J. Harlaar, co-promoter: dr. M.A. Brehm.
Research programmes

Prof. MD PhD F. Nollet (Improving functioning in complex rehabilitation populations)

PhD J.A.J.M. Beelen (Optimizing quality of care in the rehabilitation care pathways: neurological rehabilitation and children rehabilitation)

PhD S.A. Bus (Lower-extremity biomechanics and injury prevention in health and disease)

Current research funding
  • AMC
  • Crediteurenadm. VUmc, p/a Profource Service Center
  • Fior & Gentz Orthopдdietechnik
  • ZonMw