Prof. MD PhD W.S. Schlack


Prof. MD PhD W.S. Schlack

Full Professor
Main activities
Education, Patient care, Other
Focus of research

Anesthesia for the cardiac risk patient

Carioprotective effects of anesthetic agents and anesthetic strategies

Key publications
  • Schlack Wolfgang S., Boermeester Marja A. Patient safety during anaesthesia: incorporation of the WHO safe surgery guidelines into clinical practice Current opinion in anaesthesiology 2010;23 (6):754-758 [PubMed]
  • Frässdorf Jan, Borowski Andreas, Ebel Dirk, Feindt Peter, Hermes Manuel, Meemann Thomas, Weber René, Müllenheim Jost, Weber Nina C., Preckel Benedikt, Schlack Wolfgang Impact of preconditioning protocol on anesthetic-induced cardioprotection in patients having coronary artery bypass surgery Journal of thoracic and cardiovascular surgery 2009;137 (6):1436-42, 1442.e1-2 [PubMed]
All Publications
Curriculum Vitae

Training and Academic Career:
• Anaesthesia training at the Johannes-Hospital Dortmund, Prof. Dr. R. Purschke (1989-92) with a focus on cardiac anaesthesia
• 1991 Promotion University of Bonn (“Dr. med.”) “Cellular and humoral parameters in the bronchoalveolar lavage fluid”
• Scientific assistant in cardiac physiology, University of Düsseldorf, Prof. Dr. J. Schrader (1992-95)
• Since 1996, senior anaesthetist (= consultant), Dept. of Anaesthesiology, University Hospital Düsseldorf, Prof. Dr. J. Tarnow
• 1998 Habilitation University of Düsseldorf (Dr. med. habil. & nomination as “Privatdozent”): „Effect of Stellate Ganglion Block on Left Ventricular Function“
• Since 2000 „Leitender Oberarzt“ = “Chef de Clinique”
• 2003 – 2005 Full Professor of Anaesthesiology and Interim Director of the Department
• since 2006 Full Professor and Chair, Department of Anaesthesiology, Academic Medical Center, University of Amsterdam, The Netherlands

Clinical Main Topic:
• Anaesthesia for Cardiac Risk Patients
• Clinical Cardioprotection for Cardiac and Non-Cardiac Surgery

Scientific Main Topic:
• Anaesthetics and Myocardial Function, Anaesthetics and Cardioprotection
• Publications: >100 medline listed papers, several books and bookchapters

Others Commitments
• Congress Organisation: Secretary of the German Congress of Anaesthesiology in 2002, Regional Congress „Airway management“ since 2000, Chair of the Programme Committee “Circulation” of the German Society of Anaesthesiology, 2003 -2006 Chair of the Committee “Circulation“ of the European Society of Anaesthesiology (ESA) and member of the ESAs “Scientific Education“ Committee
• Examiner for the European Diploma of Anaesthesiology, for the National Final Medical Examination in Germany and the Dutch Specialist Examinations in anaesthesiology.

Research programmes

Prof. MD PhD M.W. Hollmann (Organprotection)

Prof. MD PhD W.S. Schlack (Cardiovascular Protection)

Combining the expertise of Profs Schlack, Hollmann, Preckel,  en Drs. Hauck, and Zuurbier makes for one of the world’s leading research groups in this field.  While Schlack was the intiator of this group years ago, the lead is now by the younger generation. Cardioprotective effects of various anesthetic strategies, tested on the cellular level and in animal experiments in L.E.I.C.A, were and will be tested in the clinical setting. Amongst others, the cardioprotective mechanisms of pre- and postconditioning induced by volatile anesthetics and noble gases (Xenon and Helium) will be studied in patients undergoing cardiac surgery, as well as in volunteers subjected to regional forearm ischemia/reperfusion. In collaboration with the Department of Neurology from the AMC and the Tergooi-Ziekenhuis Blaricum we start to evaluate the application of helium in patients with acute stroke. Also, patients with acute myocardial infarction may profit from helium inhalation, which will be investigated together with the Department of Cardiology of the AMC. Whether helium might also be useful after cardiac arrest will be evaluated in collaboration with the Department of Intensive Care of the AMC. In addition, the department of Anesthesiology of the AMC is the leading center for an international multicenter study on the effects of ischemic remote pre- and postconditioning on outcome after coronary artery surgery. In this patient population, molecular mechanisms of remote preconditioning will be determined, allowing translation of basic findings from animal experiments (which are performed in close collaboration with the Department of Anesthesiology, University of Düsseldorf, Germany) to the clinical situation. We also intent to investigate (in collaboration with the Department of Surgery and the Department of Medical Medicine) the phenomenon of remote postconditioning in patients subjected to kidney transplantation.

Prof. MA MD PhD B. Preckel (Patient safety, procedural sedation, cardiovascular protection, optimizing perioperative metabolism, cerebral perfusion, Wireless Monitoring)

MD PhD A.P.J. Vlaar (Transfusion related morbidity and mortality)