B. Blom PhD publications

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Publications PhD B. Blom

Position
Associate Professor
Main activities
Education, Research
Specialisation
Immunology
Focus of research

Development and function of human lymphocytes with a particular focuss on the development and function of T cells, B cells and innate lymphoid cells (ILCs) in patients that undergo allogeneic stem cell transplantations.

2020

  • van Lier Yannouck F., Davids Mark, Haverkate Nienke J. E., de Groot Pieter F., Donker Marjolein L., Meijer Ellen, Heubel-Moenen Floor C. J. I., Nur Erfan, Zeerleder Sacha S., Nieuwdorp Max, Blom Bianca, Hazenberg Mette D. Donor fecal microbiota transplantation ameliorates intestinal graft-versus-host disease in allogeneic hematopoietic cell transplant recipients Science translational medicine 2020;12 (556) [PubMed]
  • Opstelten Rianne, de Kivit Sander, Slot Manon C., van den Biggelaar Maartje, Iwaszkiewicz-Grześ Dorota, Gliwiński Mateusz, Scott Andrew M., Blom Bianca, Trzonkowski Piotr, Borst Jannie, Cuadrado Eloy, Amsen Derk GPA33: A Marker to Identify Stable Human Regulatory T Cells Journal of immunology (Baltimore, Md. 2020;204 (12):3139-3148 [PubMed]
  • Omar Saïd Z., Blom Bianca, Hazenberg Mette D. Innate lymphoid cells in treatment-induced gastrointestinal pathogenesis Current opinion in supportive and palliative care 2020;14 (2):135-141 [PubMed]

2019

  • Hazenberg Mette D., Haverkate Nienke J. E., van Lier Yannouck F., Spits Hergen, Krabbendam Lisette, Bemelman Willem A., Buskens Christianne J., Blom Bianca, Shikhagaie Medya M. Human ectoenzyme-expressing ILC3: Immunosuppressive innate cells that are depleted in graft-versus-host disease Blood advances 2019;3 (22):3650-3660 [PubMed]
  • Blom Bianca, van Hoeven Vera, Hazenberg Mette D. ILCs in hematologic malignancies: Tumor cell killers and tissue healers Seminars in immunology 2019;41:101279 [PubMed]

2018

  • Nagasawa Maho Development of human plasmacytoid dendritic cells and innate lymphoid cells 2018. 249p. ISBN 9789090312224. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Spits H. , Blom B.)
  • van Hoeven Vera, Munneke J. Marius, Cornelissen Anne S., Omar Said Z., Spruit Melchior J., Kleijer Marion, Bernink Jochem H., Blom Bianca, Voermans Carlijn, Hazenberg Mette D. Mesenchymal stromal cells stimulate the proliferation and IL-22 production of group 3 innate lymphoid cells Journal of immunology (Baltimore, Md. 2018;201 (4):1165-1173 [PubMed]

2017

  • Douaisi Marc, Resop Rachel S., Nagasawa Maho, Craft Joshua, Jamieson Beth D., Blom Bianca, Uittenbogaart Christel H. CD31, a Valuable Marker to Identify Early and Late Stages of T Cell Differentiation in the Human Thymus Journal of immunology (Baltimore, Md. 2017;198 (6):2310-2319 [PubMed]
  • Nagasawa Maho, Germar Kristine, Blom Bianca, Spits Hergen Human CD5(+) Innate Lymphoid Cells Are Functionally Immature and Their Development from CD34(+) Progenitor Cells Is Regulated by Id2 Frontiers in immunology 2017;8:1047 [PubMed]
  • Shikhagaie Medya Mara, Björklund Åsa K., Mjösberg Jenny, Erjefält Jonas S., Cornelissen Anne S., Ros Xavier Romero, Bal Suzanne M., Koning Jasper J., Mebius Reina E., Mori Michiko, Bruchard Melanie, Blom Bianca, Spits Hergen Neuropilin-1 Is Expressed on Lymphoid Tissue Residing LTi-like Group 3 Innate Lymphoid Cells and Associated with Ectopic Lymphoid Aggregates Cell reports 2017;18 (7):1761-1773 [PubMed]

2016

  • Flór Thomas B., Blom Bianca Pathogens Use and Abuse MicroRNAs to Deceive the Immune System International journal of molecular sciences 2016;17 (4):538 [PubMed]
  • Resop Rachel S., Douaisi Marc, Craft Joshua, Jachimowski Loes C. M., Blom Bianca, Uittenbogaart Christel H. Sphingosine-1-phosphate/sphingosine-1-phosphate receptor 1 signaling is required for migration of naive human T cells from the thymus to the periphery Journal of allergy and clinical immunology 2016;138 (2):551-557.e8 [PubMed]
  • Bernink Jochem H. The biology of human innate lymphoid cells 2016. 173p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Spits H.; Co-supervisor: Blom B.)

2015

  • Epeldegui Marta, Blom Bianca, Uittenbogaart Christel H. BST2/Tetherin is constitutively expressed on human thymocytes with the phenotype and function of Treg cells European journal of immunology 2015;45 (3):728-737 [PubMed]
  • Bernink Jochem H., Krabbendam Lisette, Germar Kristine, de Jong Esther, Gronke Konrad, Kofoed-Nielsen Michael, Munneke J. Marius, Hazenberg Mette D., Villaudy Julien, Buskens Christianne J., Bemelman Willem A., Diefenbach Andreas, Blom Bianca, Spits Hergen Interleukin-12 and -23 Control Plasticity of CD127(+) Group 1 and Group 3 Innate Lymphoid Cells in the Intestinal Lamina Propria Immunity 2015;43 (1):146-160 [PubMed]
  • Jachimowski Lucia Clara Maria Regulation of the multifaceted functions of human plasmacytoid dendritic cells: a polyphonic policy 2015. 184p. ISBN 9789461825384. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Spits H., Uittenbogaart C. H.; Co-supervisor: Blom B.)

2014

  • Munneke J. Marius, Björklund Andreas T., Mjösberg Jenny M., Garming-Legert Karin, Bernink Jochem H., Blom Bianca, Huisman Cynthia, van Oers Marinus H. J., Spits Hergen, Malmberg Karl-Johan, Hazenberg Mette D. Activated innate lymphoid cells are associated with a reduced susceptibility to graft-versus-host disease Blood 2014;124 (5):812-821 [PubMed]
  • Karrich Julien J., Jachimowski Loes C. M., Uittenbogaart Christel H., Blom Bianca The plasmacytoid dendritic cell as the Swiss army knife of the immune system: molecular regulation of its multifaceted functions Journal of immunology (Baltimore, Md. 2014;193 (12):5772-5778 [PubMed]

2013

  • de Jong V. Martijn, Abreu Joana R. F., Verrijn Stuart Annemarie A., van der Slik Arno R., Verhaeghen Katrijn, Engelse Marten A., Blom Bianca, Staal Frank J. T., Gorus Frans K., Roep Bart O. Alternative splicing and differential expression of the islet autoantigen IGRP between pancreas and thymus contributes to immunogenicity of pancreatic islets but not diabetogenicity in humans Diabetologia 2013;56 (12):2651-2658 [PubMed]
  • Karrich Julien J., Jachimowski Loes C. M., Nagasawa Maho, Kamp Angela, Balzarolo Melania, Wolkers Monika C., Uittenbogaart Christel H., van Ham S. Marieke, Blom Bianca IL-21-stimulated human plasmacytoid dendritic cells secrete granzyme B, which impairs their capacity to induce T-cell proliferation Blood 2013;121 (16):3103-3111 [PubMed]
  • Karrich Julien J., Jachimowski Loes C. M., Libouban Marion, Iyer Anand, Brandwijk Kim, Taanman-Kueter Esther W., Nagasawa Maho, de Jong Esther C., Uittenbogaart Christel H., Blom Bianca MicroRNA-146a regulates survival and maturation of human plasmacytoid dendritic cells Blood 2013;122 (17):3001-3009 [PubMed]
  • Gentek Rebecca, Munneke J. Marius, Helbig Christina, Blom Bianca, Hazenberg Mette D., Spits Hergen, Amsen Derk Modulation of signal strength switches Notch from an inducer of T cells to an inducer of ILC2 Frontiers in immunology 2013;4:UNSP 334 [PubMed]
  • Karrich Julien J. Plasmacytoid dendritic cells: how to control the good, the bad, the ugly at the molecular level 2013. 192p. ISBN 9789461822314. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Spits H.; Co-supervisor: Blom B.)
  • Centlivre Mireille, Legrand Nicolas, Klamer Sofieke, Liu Ying Poi, Eije Karin Jasmijn von, Bohne Martino, Rijnstra Esther Siteur-van, Weijer Kees, Blom Bianca, Voermans Carlijn, Spits Hergen, Berkhout Ben Preclinical In Vivo Evaluation of the Safety of a Multi-shRNA-based Gene Therapy Against HIV-1 Molecular therapy. Nucleic acids 2013;2:e120 [PubMed]

2012

  • Legrand Nicolas, van der Velden Gisela J., Fang Raphaël Ho Tsong, Douaisi Marc, Weijer Kees, Das Atze T., Blom Bianca, Uittenbogaart Christel H., Berkhout Ben, Centlivre Mireille A doxycycline-dependent human immunodeficiency virus type 1 replicates in vivo without inducing CD4(+) T-cell depletion Journal of general virology 2012;93 (9):2017-2027 [PubMed]
  • Diehl Sean A., Schmidlin Heike, Nagasawa Maho, Blom Bianca, Spits Hergen IL-6 Triggers IL-21 production by human CD4(+) T cells to drive STAT3-dependent plasma cell differentiation in B cells Immunology and cell biology 2012;90 (8):802-811 [PubMed]
  • Blom Bianca New Insights in the Development of Human B Lymphocytesin: Dimitra Anagnostou, Estella Matutes, editors. Bone marrow lymphoid infiltrates : Diagnosis and clinical impact. Berlin: Springer; 2012. p. 1-15, ISBN 9781447141747; 9781447141730
  • Balzarolo Melania, Karrich Julien J., Engels Sander, Blom Bianca, Medema Jan Paul, Wolkers Monika C. The transcriptional regulator NAB2 reveals a two-step induction of TRAIL in activated plasmacytoid DCs European journal of immunology 2012;42 (11):3019-3027 [PubMed]
  • Yusuf Dimas, Butland Stefanie L., Swanson Magdalena I., Bolotin Eugene, Ticoll Amy, Cheung Warren A., Zhang Xiao Yu Cindy, Dickman Christopher T. D., Fulton Debra L., Lim Jonathan S., Schnabl Jake M., Ramos Oscar H. P., Vasseur-Cognet Mireille, de Leeuw Charles N., Simpson Elizabeth M., Ryffel Gerhart U., Lam Eric W.-F., Kist Ralf, Wilson Miranda S. C., Marco-Ferreres Raquel, Brosens Jan J., Beccari Leonardo L., Bovolenta Paola, Benayoun Bérénice A., Monteiro Lara J., Schwenen Helma D. C., Grontved Lars, Wederell Elizabeth, Mandrup Susanne, Veitia Reiner A., Chakravarthy Harini, Hoodless Pamela A., Mancarelli M. Michela, Torbett Bruce E., Banham Alison H., Reddy Sekhar P., Cullum Rebecca L., Liedtke Michaela, Tschan Mario P., Vaz Michelle, Rizzino Angie, Zannini Mariastella, Frietze Seth, Farnham Peggy J., Eijkelenboom Astrid, Brown Philip J., Laperrière David, Leprince Dominique, de Cristofaro Tiziana, Prince Kelly L., Putker Marrit, del Peso Luis, Camenisch Gieri, Wenger Roland H., Mikula Michal, Rozendaal Marieke, Mader Sylvie, Ostrowski Jerzy, Rhodes Simon J., van Rechem Capucine, Boulay Gaylor, Olechnowicz Sam W. Z., Breslin Mary B., Lan Michael S., Nanan Kyster K., Wegner Michael, Hou Juan, Mullen Rachel D., Colvin Stephanie C., Noy Peter John, Webb Carol F., Witek Matthew E., Ferrell Scott, Daniel Juliet M., Park Jason, Waldman Scott A., Peet Daniel J., Taggart Michael, Jayaraman Padma-Sheela, Karrich Julien J., Blom Bianca, Vesuna Farhad, O'Geen Henriette, Sun Yunfu, Gronostajski Richard M., Woodcroft Mark W., Hough Margaret R., Chen Edwin, Europe-Finner G. Nicholas, Karolczak-Bayatti Magdalena, Bailey Jarrod, Hankinson Oliver, Raman Venu, Lebrun David P., Biswal Shyam, Harvey Christopher J., Debruyne Jason P., Hogenesch John B., Hevner Robert F., Héligon Christophe, Luo Xin M., Blank Marissa Cathleen, Millen Kathleen Joyce, Sharlin David S., Forrest Douglas, Dahlman-Wright Karin, Zhao Chunyan, Mishima Yuriko, Sinha Satrajit, Chakrabarti Rumela, Portales-Casamar Elodie, Sladek Frances M., Bradley Philip H., Wasserman Wyeth W. The Transcription Factor Encyclopedia Genome biology 2012;13 (3):R24 [PubMed]
  • Mjösberg Jenny, Bernink Jochem, Golebski Korneliusz, Karrich Julien J., Peters Charlotte P., Blom Bianca, te Velde Anje A., Fokkens Wytske J., van Drunen Cornelis M., Spits Hergen The transcription factor GATA3 is essential for the function of human type 2 innate lymphoid cells Immunity 2012;37 (4):649-659 [PubMed]
  • Karrich Julien J., Balzarolo Melania, Schmidlin Heike, Libouban Marion, Nagasawa Maho, Gentek Rebecca, Kamihira Shimeru, Maeda Takahiro, Amsen Derk, Wolkers Monika C., Blom Bianca The transcription factor Spi-B regulates human plasmacytoid dendritic cell survival through direct induction of the antiapoptotic gene BCL2-A1 Blood 2012;119 (22):5191-5200 [PubMed]

2011

  • Colantonio Arnaud D., Epeldegui Marta, Jesiak Maria, Jachimowski Loes, Blom Bianca, Uittenbogaart Christel H. IFN-α is constitutively expressed in the human thymus, but not in peripheral lymphoid organs PLoS ONE 2011;6 (8):e24252 [PubMed]

2010

  • Centlivre M., Zhou X., Pouw S. M., Weijer K., Kleibeuker W., Das A. T., Blom B., Seppen J., Berkhout B., Legrand N. Autoregulatory lentiviral vectors allow multiple cycles of doxycycline-inducible gene expression in human hematopoietic cells in vivo Gene therapy 2010;17 (1):14-25 [PubMed]
  • van Lent Anja U., Centlivre Mireille, Nagasawa Maho, Karrich Julien J., Pouw Stephan M., Weijer Kees, Spits Hergen, Blom Bianca, Legrand Nicolas In vivo modulation of gene expression by lentiviral transduction in "human immune system" Rag2-/- gamma c -/- mice Methods in molecular biology (Clifton, N.J.) 2010;595:87-115 [PubMed]
  • Schotte Remko, Schmidlin Heike, Nagasawa Maho, Dontje Wendy, Karrich Julien J., Uittenbogaart Christel, Spits Hergen, Blom Bianca Isolation and in vitro generation of gene-manipulated human plasmacytoid and conventional dendritic cells Methods in molecular biology (Clifton, N.J.) 2010;595:67-85 [PubMed]
  • Schotte Remko, Dontje Wendy, Nagasawa Maho, Yasuda Yuko, Bakker Arjen Q., Spits Hergen, Blom Bianca Synergy between IL-15 and Id2 Promotes the Expansion of Human NK Progenitor Cells, Which Can Be Counteracted by the E Protein HEB Required To Drive T Cell Development Journal of immunology (Baltimore, Md. 2010;184 (12):6670-6679 [PubMed]
  • Scheeren Ferenc A., van Lent Anja U., Nagasawa Maho, Weijer Kees, Spits Hergen, Legrand Nicolas, Blom Bianca Thymic stromal lymphopoietin induces early human B-cell proliferation and differentiation European journal of immunology 2010;40 (4):955-965 [PubMed]

2009

  • ter Brake O., Legrand N., von Eije K. J., Centlivre M., Spits H., Weijer K., Blom B., Berkhout B. Evaluation of safety and efficacy of RNAi against HIV-1 in the human immune system (Rag-2(-/-)gammac(-/-)) mouse model Gene therapy 2009;16 (1):148-153 [PubMed]
  • van Lent Anja U., Dontje Wendy, Nagasawa Maho, Siamari Rachida, Bakker Arjen Q., Pouw Stephan M., Maijoor Kelly A., Weijer Kees, Cornelissen Jan J., Blom Bianca, Di Santo James P., Spits Hergen, Legrand Nicolas IL-7 Enhances Thymic Human T Cell Development in "Human Immune System" Rag2-/-IL-2R{gamma}c-/- Mice without Affecting Peripheral T Cell Homeostasis Journal of immunology (Baltimore, Md. 2009;183 (12):7645-7655 [PubMed]
  • van Lent Anja U. G., Centlivre Mireille, Nagasawa Maho, Karrich Julien, Pouw Stephan M., Weijer Kees, Spits Hergen, Blom Bianca In Vivo Modulation of gene expression by Lentiviral Transduction in "Human Immune System" Rag2-/-yc-/-Micein: S. H. Naik, editors. Dendritic Cell Protocols. S.l.: Humana Press; 2009. p. 87-115
  • Schmidlin Heike, Diehl Sean A., Blom Bianca New insights into the regulation of human B-cell differentiation Trends in immunology 2009;30 (6):277-285 [PubMed]
  • Yoon Sun-Ok, Zhang Xin, Berner Paul, Blom Bianca, Choi Yong Sung Notch Ligands Expressed by Follicular Dendritic Cells Protect Germinal Center B Cells from Apoptosis Journal of immunology (Baltimore, Md. 2009;183 (1):352-358 [PubMed]

2008

  • Nagasawa Maho, Schmidlin Heike, Hazekamp Mark G., Schotte Remko, Blom Bianca Development of human plasmacytoid dendritic cells depends on the combined action of the basic helix-loop-helix factor E2-2 and the Ets factor Spi-B European journal of immunology 2008;38 (9):2389-2400 [PubMed]
  • Boniface Katia, Blom Bianca, Liu Yong-Jun, de Waal Malefyt René From interleukin-23 to T-helper 17 cells: human T-helper cell differentiation revisited Immunological reviews 2008;226 (1):132-146 [PubMed]
  • Dontje Wendy From progenitor cell to immune cell: Cytokines and transcription factors in human hematopoietic development. 2008. 187p. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Spits H., Blom B.)
  • Scheeren Ferenc A., Diehl Sean A., Smit Laura A., Beaumont Tim, Naspetti Marianne, Bende Richard J., Blom Bianca, Karube Kennosuke, Ohshima Koichi, van Noesel Carel J. M., Spits Hergen IL-21 is expressed in Hodgkin lymphoma and activates STAT5: evidence that activated STAT5 is required for Hodgkin lymphomagenesis Blood 2008;111 (9):4706-4715 [PubMed]
  • Schmidlin Heike, Diehl Sean A., Nagasawa Maho, Scheeren Ferenc A., Schotte Remko, Uittenbogaart Christel H., Spits Hergen, Blom Bianca Spi-B inhibits human plasma cell differentiation by repressing BLIMP1 and XBP-1 expression Blood 2008;112 (5):1804-1812 [PubMed]
  • Schmidlin Heike Transcriptional control of human plasmacytoid dendritic cell and B cell differentiation. 2008. 189p. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Spits H., Uittenbogaart Christel H.; Co-supervisor: Blom B.)

2007

  • Schotte R. Control of early human lymphoid development 2007. 148p. ISBN 9789090212191. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Spits Hergen; Co-supervisor: Blom Bianca)
  • Legrand Nicolas, Dontje Wendy, van Lent Anja U., Spits Hergen, Blom Bianca Human thymus regeneration and T cell reconstitution Seminars in immunology 2007;19 (5):280-288 [PubMed]
  • An Dong Sung, Poon Betty, Tsong Fang Raphael Ho, Weijer Kees, Blom Bianca, Spits Hergen, Chen Irvin S. Y., Uittenbogaart Christel H. Use of a novel chimeric mouse model with a functionally active human immune system to study human immunodeficiency virus type 1 infection Clinical and vaccine immunology 2007;14 (4):391-396 [PubMed]

2006

  • Dontje Wendy, Schotte Remko, Cupedo Tom, Nagasawa Maho, Scheeren Ferenc, Gimeno Ramon, Spits Hergen, Blom Bianca Delta-like1-induced Notch1 signaling regulates the human plasmacytoid dendritic cell versus T-cell lineage decision through control of GATA-3 and Spi-B Blood 2006;107 (6):2446-2452 [PubMed]
  • Blom Bianca, Spits Hergen Development of human lymphoid cells Annual review of immunology 2006;24:287-320 [PubMed]
  • Overwijk Willem W., de Visser Karin E., Tirion Felicia H., de Jong Laurina A., Pols Thijs W. H., van der Velden Yme U., van den Boorn Jasper G., Keller Anna M., Buurman Wim A., Theoret Marc R., Blom Bianca, Restifo Nicholas P., Kruisbeek Ada M., Kastelein Robert A., Haanen John B. A. G. Immunological and antitumor effects of IL-23 as a cancer vaccine adjuvant Journal of immunology (Baltimore, Md. 2006;176 (9):5213-5222 [PubMed]
  • Schmidlin Heike, Dontje Wendy, Groot Fedde, Ligthart Suzanne J., Colantonio Arnaud D., Oud Monique E., Schilder-Tol Esther J., Spaargaren Marcel, Spits Hergen, Uittenbogaart Christel H., Blom Bianca Stimulated plasmacytoid dendritic cells impair human T-cell development Blood 2006;108 (12):3792-3800 [PubMed]

2005

  • Cupedo Tom, Nagasawa Maho, Weijer Kees, Blom Bianca, Spits Hergen Development and activation of regulatory T cells in the human fetus European journal of immunology 2005;35 (2):383-390 [PubMed]
  • Scheeren Ferenc A., Naspetti Marianne, Diehl Sean, Schotte Remko, Nagasawa Maho, Wijnands Erwin, Gimeno Ramon, Vyth-Dreese Florry A., Blom Bianca, Spits Hergen STAT5 regulates the self-renewal capacity and differentiation of human memory B cells and controls Bcl-6 expression Nature immunology 2005;6 (3):303-313 [PubMed]

2004

  • Gurney Kevin B., Colantonio Arnaud D., Blom Bianca, Spits Hergen, Uittenbogaart Christel H. Endogenous IFN-alpha production by plasmacytoid dendritic cells exerts an antiviral effect on thymic HIV-1 infection Journal of immunology (Baltimore, Md. 2004;173 (12):7269-7276 [PubMed]
  • Gimeno Ramon, Weijer Kees, Voordouw Arie, Uittenbogaart Christel H., Legrand Nicolas, Alves Nuno L., Wijnands Erwin, Blom Bianca, Spits Hergen Monitoring the effect of gene silencing by RNA interference in human CD34+ cells injected into newborn RAG2-/- gammac-/- mice: functional inactivation of p53 in developing T cells Blood 2004;104 (13):3886-3893 [PubMed]
  • Schotte Remko, Nagasawa Maho, Weijer Kees, Spits Hergen, Blom Bianca The ETS transcription factor Spi-B is required for human plasmacytoid dendritic cell development Journal of experimental medicine 2004;200 (11):1503-1509 [PubMed]
  • Chen Wei, Antonenko Svetlana, Sederstrom Joel M., Liang Xueqing, Chan Anissa S. H., Kanzler Holger, Blom Bianca, Blazar Bruce R., Liu Yong-Jun Thrombopoietin cooperates with FLT3-ligand in the generation of plasmacytoid dendritic cell precursors from human hematopoietic progenitors Blood 2004;103 (7):2547-2553 [PubMed]

2002

  • Blom Bianca, Ligthart Suzanne J. W. C., Schotte Remko, Spits Hergen Developmental origin of pre-DC2 Human immunology 2002;63 (12):1072-1080 [PubMed]
  • Weijer Kees, Uittenbogaart Christel H., Voordouw Arie, Couwenberg Franka, Seppen Jurgen, Blom Bianca, Vyth-Dreese Florry A., Spits Hergen Intrathymic and extrathymic development of human plasmacytoid dendritic cell precursors in vivo Blood 2002;99 (8):2752-2759 [PubMed]

1999

  • Blom B., Heemskerk M. H., Verschuren M. C., van Dongen J. J., Stegmann A. P., Bakker A. Q., Couwenberg F., Res P. C., Spits H. Disruption of alpha beta but not of gamma delta T cell development by overexpression of the helix-loop-helix protein Id3 in committed T cell progenitors EMBO journal 1999;18 (10):2793-2802 [PubMed]
  • Jacobs H., Krimpenfort P., Haks M., Allen J., Blom B., Démollière C., Kruisbeek A., Spits H., Berns A. PIM1 reconstitutes thymus cellularity in interleukin 7- and common gamma chain-mutant mice and permits thymocyte maturation in Rag- but not CD3gamma-deficient mice Journal of experimental medicine 1999;190 (8):1059-1068 [PubMed]
  • Blom B., Verschuren M. C., Heemskerk M. H., Bakker A. Q., van Gastel-Mol E. J., Wolvers-Tettero I. L., van Dongen J. J., Spits H. TCR gene rearrangements and expression of the pre-T cell receptor complex during human T-cell differentiation Blood 1999;93 (9):3033-3043 [PubMed]

1998

  • Spits H., Blom B., Jaleco A. C., Weijer K., Verschuren M. C., van Dongen J. J., Heemskerk M. H., Res P. C. Early stages in the development of human T, natural killer and thymic dendritic cells Immunological reviews 1998;165:75-86 [PubMed]
  • Verschuren M. C., Blom B., Bogers A. J., Spits H., van Dongen J. J. PJA-BP expression and TCR delta deletion during human T cell differentiation International immunology 1998;10 (12):1873-1880 [PubMed]
  • Blom B., Res P. C., Spits H. T cell precursors in man and mice Critical reviews in immunology 1998;18 (4):371-388 [PubMed]

1997

  • Res P., Blom B., Hori T., Weijer K., Spits H. Downregulation of CD1 marks acquisition of functional maturation of human thymocytes and defines a control point in late stages of human T cell development Journal of experimental medicine 1997;185 (1):141-151 [PubMed]
  • Jaleco A. C., Blom B., Res P., Weijer K., Lanier L. L., Phillips J. H., Spits H. Fetal liver contains committed NK progenitors, but is not a site for development of CD34+ cells into T cells Journal of immunology (Baltimore, Md. 1997;159 (2):694-702 [PubMed]
  • Heemskerk M. H., Blom B., Nolan G., Stegmann A. P., Bakker A. Q., Weijer K., Res P. C., Spits H. Inhibition of T cell and promotion of natural killer cell development by the dominant negative helix loop helix factor Id3 Journal of experimental medicine 1997;186 (9):1597-1602 [PubMed]
  • Blom B., Res P., Noteboom E., Weijer K., Spits H. Prethymic CD34+ progenitors capable of developing into T cells are not committed to the T cell lineage Journal of immunology (Baltimore, Md. 1997;158 (8):3571-3577 [PubMed]