B.D.M. Boeser-Nunnink BEng publications

2020

• Kruize Zita, Maurer Irma, Boeser-Nunnink Brigitte D. M., Booiman Thijs, Kootstra Neeltje A. Genetic variations in the host dependency factors ALCAM and TPST2 impact HIV-1 disease progression AIDS (London, England) 2020;34 (9):1303-1312 [PubMed]

2018

• De Francesco Davide, Verboeket Sebastiaan O, Underwood Jonathan, Bagkeris Emmanouil , Wit Ferdinand W, Mallon Patrick W G, Winston Alan, Reiss Peter, Sabin Caroline A, Study group members AMC , Reiss P. , Wit F. W. N. M., Kooij K. W., van Zoest R. A. , Verheij E. , Verboeket Sebastiaan O., Prins M. , Kootstra N. A., Harskamp-Holwerda A. M. , Maurer Irma, Mangas Ruiz M. M., Boeser-Nunnink B. D. M. , Geerlings S. E. , Goorhuis A. , Hovius J. W. R. , Nellen F. J. B. , van der Poll Tom, Prins J. M. , Wiersinga W. J. , van Vugt M. , de Bree G. J. , Postema P. G. , Bisschop P. H. L. T., Serlie M. J. M. , Dekker E. , van der Velde N. , Willemsen J. M. R., Vogt L. , Portegies P. , Schmand B. A. , Geurtsen G. J. , Verbraak F. D. , Visser I. , Nieuwkerk P. T. , Majoie C. B. L. M. , Caan M. W. A. , van Lunsen H. W. , van den Born B. J. H. , Stroes E. S. G. Patterns of co-occurring comorbidities in people living with HIV Open forum infectious diseases 2018;5 (11):ofy272 [PubMed]
• van Zoest Rosan A., Underwood Jonathan, de Francesco Davide, Sabin Caroline A., Cole James H., Wit Ferdinand W., Caan Matthan W. A., Kootstra Neeltje A., Fuchs Dietmar, Zetterberg Henrik, Majoie Charles B. L. M., Portegies Peter, Winston Alan, Sharp David J., Gisslén Magnus, Reiss Peter, Winston A., Prins M., Schim van der Loeff M. F., Schouten J., Schmand B., Geurtsen G. J., Sharp D. J., Villaudy J., Berkhout B., Gisslén M., Pasternak A., Sabin C. A., Guaraldi G., Bürkle A., Libert C., Franceschi C., Kalsbeek A., Fliers E., Hoeijmakers J., Pothof J., van der Valk M., Bisschop P. H., Zaheri S., Burger D., Cole J. H., Zikkenheiner W., Janssen F. R., Underwood J., Kooij K. W., Doyle N., Verbraak F., Demirkaya N., Weijer K., Boeser-Nunnink B. Structural Brain Abnormalities in Successfully Treated HIV Infection: Associations With Disease and Cerebrospinal Fluid Biomarkers Journal of infectious diseases 2018;217 (1):69-81 [PubMed]

2017

• Booiman Thijs, Wit Ferdinand W., Maurer Irma, de Francesco Davide, Sabin Caroline A., Harskamp Agnes M., Prins Maria, Garagnani Paolo, Pirazzini Chiara, Franceschi Claudio, Fuchs Dietmar, Gisslén Magnus, Winston Alan, Reiss Peter, Kootstra Neeltje A., Schouten J., Kooij K. W., van Zoest R. A., Elsenga B. C., Janssen F. R., Heidenrijk M., Zikkenheiner W., van der Valk M., Booiman T., Harskamp-Holwerda A. M., Boeser-Nunnink B., Maurer I., Mangas Ruiz M. M., Girigorie A. F., Villaudy J., Frankin E., Pasternak A., Berkhout B., van der Kuyl T., Portegies P., Schmand B. A., Geurtsen G. J., ter Stege J. A., Klein Twennaar M., Majoie C. B. L. M., Caan M. W. A., Su T., Weijer K., Bisschop P. H. L. T., Kalsbeek A., Wezel M., Visser I., Ruhé H. G., Franceschi C., Garagnani P. High Cellular Monocyte Activation in People Living With Human Immunodeficiency Virus on Combination Antiretroviral Therapy and Lifestyle-Matched Controls Is Associated With Greater Inflammation in Cerebrospinal Fluid Open forum infectious diseases 2017;4 (3):ofx108 [PubMed]

2016

• Kooij Katherine W., Wit Ferdinand W. N. M., Booiman Thijs, van der Valk Marc, Schim van der Loeff Maarten F., Kootstra Neeltje A., Reiss Peter, Schouten J., van Zoest R. A., Verheij E., Elsenga B. C., Prins M., Martens M., Moll S., Berkel J., Totté M., Visser G. R., May L., Kovalev S., Newsum A., Boeser-Nunnink B., Geerlings S. E., Godfried M. H., Goorhuis A., Hovius J. W. R., van der Meer J. T. M., Nellen F. J. B., van der Poll T., Prins J. M., Wiersinga W. J., van Vugt M., Postema P. G., Bisschop P. H. L. T., Serlie M. J. M., Dekker E., van der Velde N., Vogt L., Portegies P., Schmand B. A., Geurtsen G. J., Verbraak F. D., Demirkaya N., Nieuwkerk P. T., Langebeek N., van Steenwijk R. P., Majoie C. B. L. M., Caan M. W. A., van Lunsen H. W., van den Born B. J. H., Stroes E. S. G. Cigarette Smoking and Inflammation, Monocyte Activation, and Coagulation in HIV-Infected Individuals Receiving Antiretroviral Therapy, Compared With Uninfected Individuals Journal of infectious diseases 2016;214 (12):1817-1821 [PubMed]
• Ploquin Mickaël J., Madec Yoann, Casrouge Armanda, Huot Nicolas, Passaes Caroline, Lécuroux Camille, Essat Asma, Boufassa Faroudy, Jacquelin Béatrice, Jochems Simon P., Petitjean Gaël, Angin Mathieu, Gärtner Kathleen, Garcia-Tellez Thalía, Noël Nicolas, Booiman Thijs, Boeser-Nunnink Brigitte D., Roques Pierre, Saez-Cirion Asier, Vaslin Bruno, Dereudre-Bosquet Nathalie, Barré-Sinoussi Françoise, Ghislain Mathilde, Rouzioux Christine, Lambotte Olivier, Albert Matthew L., Goujard Cécile, Kootstra Neeltje, Meyer Laurence, Müller-Trutwin Michaela C. Elevated Basal Pre-infection CXCL10 in Plasma and in the Small Intestine after Infection Are Associated with More Rapid HIV/SIV Disease Onset PLoS pathogens 2016;12 (8):e1005774 [PubMed]
• van den Kerkhof Tom L. G. M., de Taeye Steven W., Boeser-Nunnink Brigitte D., Burton Dennis R., Kootstra Neeltje A., Schuitemaker Hanneke, Sanders Rogier W., van Gils Marit J. HIV-1 escapes from N332-directed antibody neutralization in an elite neutralizer by envelope glycoprotein elongation and introduction of unusual disulfide bonds Retrovirology 2016;13 (1):48 [PubMed]
• van den Kerkhof Tom L. G. M., van Gils Marit J., Boeser-Nunnink Brigitte D., Burger Judith A., Schuitemaker Hanneke, Sanders Rogier W. Probability of N332 glycan occupancy on HIV-1 gp120 modulates sensitivity to broadly neutralizing antibodies AIDS (London, England) 2016;30 (14):2179-2184 [PubMed]
• Cobos Jiménez Viviana, Wit Ferdinand W. N. M., Joerink Maaike, Maurer Irma, Harskamp Agnes M., Schouten Judith, Prins Maria, van Leeuwen Ester M. M., Booiman Thijs, Deeks Steven G., Reiss Peter, Kootstra Neeltje A., van der Valk M., Kooij K. W., van Zoest R. A., Elsenga B. C., Prins M., Martens M., Boeser-Nunnink B., Geerlings S. E., Godfried M. H., Goorhuis A., Hovius J. W. R., Nellen F. J. B., van der Meer J. T. M., van der Poll T., Prins J. M., Wiersinga W. J., Postema P. G., Bisschop P. H. L. T., Serlie M. J. M., Dekker E., de Rooij S. E. J. A., Vogt L., Portegies P., Schmand B. A., Geurtsen G. J., van Eck-Smit B. L. F., de Jong M., Richel D. J., Verbraak F. D., Demirkaya N., Ruhé H. G., Nieuwkerk P. T., van Steenwijk R. P., Majoie C. B. L. M., Caan M. W. A., van Lunsen H. W., van den Born B. J. H., Stroes E. S. G. T-Cell Activation Independently Associates With Immune Senescence in HIV-Infected Recipients of Long-term Antiretroviral Treatment Journal of infectious diseases 2016;214 (2):216-225 [PubMed]
• Cornelissen Marion, Euler Zelda, van den Kerkhof Tom L. G. M., van Gils Marit J., Boeser-Nunnink Brigitte D. M., Kootstra Neeltje A., Zorgdrager Fokla, Schuitemaker Hanneke, Prins Jan M., Sanders Rogier W., van der Kuyl Antoinette C. The Neutralizing Antibody Response in an Individual with Triple HIV-1 Infection Remains Directed at the First Infecting Subtype AIDS research and human retroviruses 2016;32 (10-11):1135-1142 [PubMed]

2014

• van den Kerkhof Tom L. G. M., Euler Zelda, van Gils Marit J., Boeser-Nunnink Brigitte D., Schuitemaker Hanneke, Sanders Rogier W. Early development of broadly reactive HIV-1 neutralizing activity in elite neutralizers AIDS (London, England) 2014;28 (8):1237-1240 [PubMed]

2013

• Euler Zelda, van Gils Marit J., Boeser-Nunnink Brigitte D., Schuitemaker Hanneke, van Manen Daniëlle Genome-wide association study on the development of cross-reactive neutralizing antibodies in HIV-1 infected individuals PLoS ONE 2013;8 (1):e54684 [PubMed]
• van den Kerkhof Tom L. G. M., Feenstra K. A., Euler Zelda, van Gils Marit J., Rijsdijk Linda W. E., Boeser-Nunnink Brigitte D., Heringa Jaap, Schuitemaker Hanneke, Sanders Rogier W. HIV-1 envelope glycoprotein signatures that correlate with the development of cross-reactive neutralizing activity Retrovirology 2013;10 (1) [PubMed]

2012

• Bol Sebastiaan M., Booiman Thijs, van Manen Daniëlle, Bunnik Evelien M., van Sighem Ard I., Sieberer Margit, Boeser-Nunnink Brigitte, de Wolf Frank, Schuitemaker Hanneke, Portegies Peter, Kootstra Neeltje A., van 't Wout Angélique B. Single Nucleotide Polymorphism in Gene Encoding Transcription Factor Prep1 Is Associated with HIV-1-Associated Dementia PLoS ONE 2012;7 (2):e30990 [PubMed]
• Edo-Matas Diana, Rachinger Andrea, Setiawan Laurentia C., Boeser-Nunnink Brigitte D., van 't Wout Angélique B., Lemey Philippe, Schuitemaker Hanneke The evolution of human immunodeficiency virus type-1 (HIV-1) envelope molecular properties and coreceptor use at all stages of infection in an HIV-1 donor-recipient pair Virology 2012;422 (1):70-80 [PubMed]

2011

• Euler Zelda, Bunnik Evelien M., Burger Judith A., Boeser-Nunnink Brigitte D. M., Grijsen Marlous L., Prins Jan M., Schuitemaker Hanneke Activity of broadly neutralizing antibodies, including PG9, PG16, and VRC01, against recently transmitted subtype B HIV-1 variants from early and late in the epidemic Journal of virology 2011;85 (14):7236-7245 [PubMed]
• van Manen Daniëlle, Delaneau Olivier, Kootstra Neeltje A., Boeser-Nunnink Brigitte D., Limou Sophie, Bol Sebastiaan M., Burger Judith A., Zwinderman Aeilko H., Moerland Perry D., van 't Slot Ruben, Zagury Jean-François, van 't Wout Angélique B., Schuitemaker Hanneke Genome-wide association scan in HIV-1-infected individuals identifying variants influencing disease course PLoS ONE 2011;6 (7):e22208 [PubMed]
• van Gils Marit J., Bunnik Evelien M., Boeser-Nunnink Brigitte D., Burger Judith A., Terlouw-Klein Marijke, Verwer Naomi, Schuitemaker Hanneke Longer V1V2 region with increased number of potential N-linked glycosylation sites in the HIV-1 envelope glycoprotein protects against HIV-specific neutralizing antibodies Journal of virology 2011;85 (14):6986-6995 [PubMed]
• Schellens Ingrid M. M., Navis Marjon, van Deutekom Hanneke W. M., Boeser-Nunnink Brigitte, Berkhout Ben, Kootstra Neeltje, Miedema Frank, Keşmir Can, Schuitemaker Hanneke, van Baarle Debbie, Borghans José A. M. Loss of HIV-1-derived cytotoxic T lymphocyte epitopes restricted by protective HLA-B alleles during the HIV-1 epidemic AIDS (London, England) 2011;25 (14):1691-1700 [PubMed]
• van Manen Daniëlle, Gras Luuk, Boeser-Nunnink Brigitte D., van Sighem Ard I., Maurer Irma, Mangas Ruiz Marga M., Harskamp Agnes M., Steingrover Radjin, Prins Jan M., de Wolf Frank, van 't Wout Angélique B., Schuitemaker Hanneke Rising HIV-1 viral load set point at a population level coincides with a fading impact of host genetic factors on HIV-1 control AIDS (London, England) 2011;25 (18):2217-2226 [PubMed]

2010

• Bunnik Evelien M., Euler Zelda, Welkers Matthijs R. A., Boeser-Nunnink Brigitte D. M., Grijsen Marlous L., Prins Jan M., Schuitemaker Hanneke Adaptation of HIV-1 envelope gp120 to humoral immunity at a population level Nature medicine 2010;16 (9):995-997 [PubMed]
• van Manen Danielle, Kootstra Neeltje A., Boeser-Nunnink Brigitte, Handulle Muna A. M., van 't Wout Angelique B., Schuitemaker Hanneke Association of HLA-C and HCP5 gene regions with the clinical course of HIV-1 infection (vol 23, pg 19, 2009) AIDS (London, England) 2010;24 (6):939
• Edo-Matas Diana, van Gils Marit J., Bowles Emma J., Navis Marjon, Rachinger Andrea, Boeser-Nunnink Brigitte, Stewart-Jones Guillaume B., Kootstra Neeltje A., Wout Angélique B. van 't, Schuitemaker Hanneke Genetic composition of replication competent clonal HIV-1 variants isolated from peripheral blood mononuclear cells (PBMC), HIV-1 proviral DNA from PBMC and HIV-1 RNA in serum in the course of HIV-1 infection Virology 2010;405 (2):492-504 [PubMed]

2009

• van Manen Daniëlle, Kootstra Neeltje A., Boeser-Nunnink Brigitte, Handulle Muna Am, Vanʼt Wout Angélique B., Schuitemaker Hanneke Association of HLA-C and HCP5 gene regions with the clinical course of HIV-1 infection AIDS (London, England) 2009;23 (1):19-28 [PubMed]

2007

• Quakkelaar Esther D., Bunnik Evelien M., van Alphen Floris P. J., Boeser-Nunnink Brigitte D. M., van Nuenen Ad C., Schuitemaker Hanneke Escape of human immunodeficiency virus type 1 from broadly neutralizing antibodies is not associated with a reduction of viral replicative capacity in vitro Virology 2007;363 (2):447-453 [PubMed]
• Bunnik Evelien M., Quakkelaar Esther D., van Nuenen Ad C., Boeser-Nunnink Brigitte, Schuitemaker Hanneke Increased neutralization sensitivity of recently emerged CXCR4-using human immunodeficiency virus type 1 strains compared to coexisting CCR5-using variants from the same patient Journal of virology 2007;81 (2):525-531 [PubMed]
• Quakkelaar Esther D., van Alphen Floris P. J., Boeser-Nunnink Brigitte D. M., van Nuenen Ad C., Pantophlet Ralph, Schuitemaker Hanneke Susceptibility of recently transmitted subtype B human immunodeficiency virus type 1 variants to broadly neutralizing antibodies Journal of virology 2007;81 (16):8533-8542 [PubMed]
• Quakkelaar Esther D., Beaumont Tim, van Nuenen Ad C., van Alphen Floris P. J., Boeser-Nunnink Brigitte D. M., van 't Wout Angélique B., Schuitemaker Hanneke T cell line passage can select for pre-existing neutralization-sensitive variants from the quasispecies of primary human immunodeficiency virus type-1 isolates Virology 2007;359 (1):92-104 [PubMed]

2005

• van der Bij Akke K., Kloosterboer Nico, Prins Maria, Boeser-Nunnink Brigitte, Geskus Ronald B., Lange Joep M. A., Coutinho Roel A., Schuitemaker Hanneke GB virus C coinfection and HIV-1 disease progression: The Amsterdam Cohort Study Journal of infectious diseases 2005;191 (5):678-685 [PubMed]
• van der Bij A. K., Kloosterboer N., Prins Maria, Boeser-Nunnink B., Geskus R. B., Lange J. M. A., Coutinho R. A., Schuitemaker H. GB virus C infection and survival in the Amsterdam Cohort study - Reply to George and to Stapleton et al Journal of infectious diseases 2005;191 (12):2158-2160

2004

• Stalmeijer Evelien H. B., van Rij Ronald P., Boeser-Nunnink Brigitte, Visser Janny A., Naarding Marloes A., Schols Dominique, Schuitemaker Hanneke In vivo evolution of X4 human immunodeficiency virus type 1 variants in the natural course of infection coincides with decreasing sensitivity to CXCR4 antagonists Journal of virology 2004;78 (6):2722-2728 [PubMed]

2003

• Kwa David, van Rij Ronald P., Boeser-Nunnink Brigitte, Vingerhoed Jose, Schuitemaker Hanneke Association between an interleukin-4 promoter polymorphism and the acquisition of CXCR4 using HIV-1 variants AIDS (London, England) 2003;17 (7):981-985 [PubMed]
• Koning Fransje A., Kwa David, Boeser-Nunnink Brigitte, Dekker Jos, Vingerhoed Jose, Hiemstra Harry, Schuitemaker Hanneke Decreasing sensitivity to RANTES (regulated on activation, normally T cell-expressed and -secreted) neutralization of CC chemokine receptor 5-using, non-syncytium-inducing virus variants in the course of human immunodeficiency virus type 1 infection Journal of infectious diseases 2003;188 (6):864-872 [PubMed]
• Kwa David, Vingerhoed Jose, Boeser Brigitte, Schuitemaker Hanneke Increased in vitro cytopathicity of CC chemokine receptor 5-restricted human immunodeficiency virus type 1 primary isolates correlates with a progressive clinical course of infection Journal of infectious diseases 2003;187 (9):1397-1403 [PubMed]
• Kwa David, Boeser-Nunnink Brigitte, Schuitemaker Hanneke Lack of evidence for an association between a polymorphism in CX3CR1 and the clinical course of HIV infection or virus phenotype evolution AIDS (London, England) 2003;17 (5):759-761 [PubMed]

2001

• Kwa D., Vingerhoed J., Boeser-Nunnink B., Broersen S., Schuitemaker H. Cytopathic effects of non-syncytium-inducing and syncytium-inducing human immunodeficiency virus type 1 variants on different CD4(+)-T-cell subsets are determined only by coreceptor expression Journal of virology 2001;75 (21):10455-10459 [PubMed]

1997

• Bruisten S. M., Oudshoorn P., van Swieten P., Boeser-Nunnink B., van Aarle P., Tondreau S. P., Cuypers H. T. Stability of HIV-1 RNA in blood during specimen handling and storage prior to amplification by NASBA-QT Journal of virological methods 1997;67 (2):199-207 [PubMed]

1994

• Bresters D., Schipper M. E., Reesink H. W., Boeser-Nunnink B. D., Cuypers H. T. The duration of fixation influences the yield of HCV cDNA-PCR products from formalin-fixed, paraffin-embedded liver tissue Journal of virological methods 1994;48 (2-3):267-272 [PubMed]

1992

• Schuuring E., Verhoeven E., van Tinteren H., Peterse J. L., Nunnink B., Thunnissen F. B., Devilee P., Cornelisse C. J., van de Vijver M. J., Mooi W. J. Amplification of genes within the chromosome 11q13 region is indicative of poor prognosis in patients with operable breast cancer Cancer research 1992;52 (19):5229-5234 [PubMed]
• Bresters D., Cuypers H. T., Reesink H. W., Chamuleau R. A., Schipper M. E., Boeser-Nunnink B. D., Lelie P. N., Jansen P. L. Detection of hepatitis C viral RNA sequences in fresh and paraffin-embedded liver biopsy specimens of non-A, non-B hepatitis patients Journal of hepatology 1992;15 (3):391-395 [PubMed]