I.A.M. Derks BEng publications

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Publications BEng I.A.M. Derks

Position
Support Staff
Main activities
Research
Specialisation
Apoptosis signaling in immunity
Focus of research

Apoptosis in the immunesystem

2020

  • Martens Anne W. J., Janssen Susanne R., Derks Ingrid A. M., Adams Iii Homer C., Izhak Liat, van Kampen Roel, Tonino Sanne H., Eldering Eric, van der Windt Gerritje J. W., Kater Arnon P. CD3xCD19 DART molecule treatment induces non-apoptotic killing and is efficient against high-risk chemotherapy and venetoclax-resistant chronic lymphocytic leukemia cells Journal for immunotherapy of cancer 2020;8 (1) [PubMed]

2016

  • Thijssen Rachel, ter Burg Johanna, Garrick Brett, van Bochove Gregor G. W., Brown Jennifer R., Fernandes Stacey M., Rodríguez María Solé, Michot Jean-Marie, Hallek Michael, Eichhorst Barbara, Reinhardt Hans Christian, Bendell Johanna, Derks Ingrid A. M., van Kampen Roel J. W., Hege Kristen, Kersten Marie José, Trowe Torsten, Filvaroff Ellen H., Eldering Eric, Kater Arnon P. Dual TORK/DNA-PK inhibition blocks critical signaling pathways in chronic lymphocytic leukemia Blood 2016;128 (4):574-583 [PubMed]

2015

  • te Raa G. D., Moerland P. D., Leeksma A. C., Derks I. A., Yigittop H., Laddach N., Loden-van Straaten M., Navrkalova V., Trbusek M., Luijks D. M., Zenz T., Skowronska A., Hoogendoorn M., Stankovic T., van Oers M. H., Eldering E., Kater A. P. Assessment of p53 and ATM functionality in chronic lymphocytic leukemia by multiplex ligation-dependent probe amplification Cell death & disease 2015;6:e1852 [PubMed]
  • Vieira Braga Felipe A., Hertoghs Kirsten M. L., Kragten Natasja A. M., Doody Gina M., Barnes Nicholas A., Remmerswaal Ester B. M., Hsiao Cheng-Chih, Moerland Perry D., Wouters Diana, Derks Ingrid A. M., van Stijn Amber, Demkes Marc, Hamann Jörg, Eldering Eric, Nolte Martijn A., Tooze Reuben M., ten Berge Ineke J. M., van Gisbergen Klaas P. J. M., van Lier René A. W. Blimp-1 homolog Hobit identifies effector-type lymphocytes in humans European journal of immunology 2015;45 (10):2945-2958 [PubMed]
  • Tonino Sanne H., Mulkens Chantal E., van Laar Jacoline, Derks Ingrid A. M., Suo Guangli, Croon-de Boer Fransien, van Oers Marinus H. J., Eldering Eric, Wang Jean Y., Kater Arnon P. Induction of TAp73 by platinum-based compounds to overcome drug resistance in p53 dysfunctional chronic lymphocytic leukemia Leukemia & lymphoma 2015;56 (8):2439-2447 [PubMed]
  • te Raa G. D., Derks I. A. M., Navrkalova V., Skowronska A., Moerland P. D., van Laar J., Oldreive C., Monsuur H., Trbusek M., Malcikova J., Lodén M., Geisler C. H., Hüllein J., Jethwa A., Zenz T., Pospisilova S., Stankovic T., van Oers M. H. J., Kater A. P., Eldering E. The impact of SF3B1 mutations in CLL on the DNA-damage response Leukemia 2015;29 (5):1133-1142 [PubMed]

2013

  • Wensveen Felix M., Geest Christian R., Libregts Sten F. W. M., Derks Ingrid A. M., Ekert Paul G., Labi Verena, Villunger Andreas, Nolte Martijn A., Eldering Eric BH3-only protein Noxa contributes to apoptotic control of stress-erythropoiesis Apoptosis 2013;18 (11):1306-1318 [PubMed]
  • Pascutti Maria Fernanda, Jak Margot, Tromp Jacqueline M., Derks Ingrid A. M., Remmerswaal Ester B. M., Thijssen Rachel, van Attekum Martijn H. A., van Bochove Gregor G., Luijks Dieuwertje M., Pals Steven T., van Lier René A. W., Kater Arnon P., van Oers Marinus H. J., Eldering Eric IL-21 and CD40L signals from autologous T cells can induce antigen-independent proliferation of CLL cells Blood 2013;122 (17):3010-3019 [PubMed]
  • Wensveen Felix M., Klarenbeek Paul L., van Gisbergen Klaas P. J. M., Pascutti Maria F., Derks Ingrid A. M., van Schaik Barbera D. C., ten Brinke Anja, de Vries Niek, Cekinovic Durdica, Jonjic Stipan, van Lier René A. W., Eldering Eric Pro-apoptotic protein Noxa regulates memory T cell population size and protects against lethal immunopathology Journal of immunology (Baltimore, Md. 2013;190 (3):1180-1191 [PubMed]

2012

  • Wensveen Felix M., Derks Ingrid A. M., van Gisbergen Klaas P. J. M., de Bruin Alex M., Meijers Joost C. M., Yigittop Haciali, Nolte Martijn A., Eldering Eric, van Lier René A. W. BH3-only protein Noxa regulates apoptosis in activated B cells and controls high-affinity antibody formation Blood 2012;119 (6):1440-1449 [PubMed]
  • Wensveen Felix M., Unger Peter-Paul A., Kragten Natasja A. M., Derks Ingrid A. M., ten Brinke Anja, Arens Ramon, van Lier Rene A. W., Eldering Eric, van Gisbergen Klaas P. J. M. CD70-Driven Costimulation Induces Survival or Fas-Mediated Apoptosis of T Cells Depending on Antigenic Load Journal of immunology (Baltimore, Md. 2012;188 (9):4256-4267 [PubMed]
  • Helbig Christina, Gentek Rebecca, Backer Ronald A., de Souza Yevan, Derks Ingrid A. M., Eldering Eric, Wagner Koen, Jankovic Dragana, Gridley Thomas, Moerland Perry D., Flavell Richard A., Amsen Derk Notch controls the magnitude of T helper cell responses by promoting cellular longevity Proceedings of the National Academy of Sciences of the United States of America 2012;109 (23):9041-9046 [PubMed]

2011

  • Kuijpers Taco W., Baars Paul A., Aan de Kerk Daan J., Jansen Machiel H., Derks Ingrid A. M., Bredius Robbert G. M., Sanders Elisabeth A. M., van der Burg Mirjam, Alders Marielle, van Lier Rene A. W. A novel mutation in CD132 causes X-CID with defective T-cell activation and impaired humoral reactivity Journal of allergy and clinical immunology 2011;128 (6):1360-1363.e4 [PubMed]
  • Wensveen Felix M., Alves Nuno L., Derks Ingrid A. M., Reedquist Kris A., Eldering Eric Apoptosis induced by overall metabolic stress converges on the Bcl-2 family proteins Noxa and Mcl-1 Apoptosis 2011;16 (7):708-721 [PubMed]

2010

  • Wensveen Felix M., van Gisbergen Klaas P. J. M., Derks Ingrid A. M., Gerlach Carmen, Schumacher Ton N., van Lier René A. W., Eldering Eric Apoptosis Threshold Set by Noxa and Mcl-1 after T Cell Activation Regulates Competitive Selection of High-Affinity Clones Immunity 2010;32 (6):754-765 [PubMed]
  • Kuijpers Taco W., Bende Richard J., Baars Paul A., Grummels Annette, Derks Ingrid A. M., Dolman Koert M., Beaumont Tim, Tedder Thomas F., van Noesel Carel J. M., Eldering Eric, van Lier René A. W. CD20 deficiency in humans results in impaired T cell-independent antibody responses Journal of clinical investigation 2010;120 (1):214-222 [PubMed]

2008

  • Alves Nuno L., van Leeuwen Ester M. M., Derks Ingrid A. M., van Lier René A. W. Differential regulation of human IL-7 receptor alpha expression by IL-7 and TCR signaling Journal of immunology (Baltimore, Md. 2008;180 (8):5201-5210 [PubMed]

2007

  • Hallaert D. Y. H., Spijker R., Jak M., Derks I. A. M., Alves N. L., Wensveen F. M., de Boer J. P., de Jong D., Green S. R., van Oers M. H. J., Eldering E. Crosstalk among Bcl-2 family members in B-CLL: seliciclib acts via the Mcl-1/Noxa axis and gradual exhaustion of Bcl-2 protection Cell death and differentiation 2007;14 (11):1958-1967 [PubMed]

2006

  • Alves Nuno L., Derks Ingrid A. M., Berk Erik, Spijker René, van Lier René A. W., Eldering Eric The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells Immunity 2006;24 (6):703-716 [PubMed]

2004

  • Eldering Eric, Mackus Wendelina J. M., Derks Ingrid A. M., Evers Ludo M., Beuling Esther, Teeling Peter, Lens Susanne M. A., van Oers Marinus H. J., van Lier René A. W. Apoptosis via the B cell antigen receptor requires Bax translocation and involves mitochondrial depolarization, cytochrome C release, and caspase-9 activation European journal of immunology 2004;34 (7):1950-1960 [PubMed]

2003

  • Eldering Eric, Spek C. Arnold, Aberson Hella L., Grummels Annette, Derks Ingrid A., de Vos Alex F., McElgunn Cathal J., Schouten Jan P. Expression profiling via novel multiplex assay allows rapid assessment of gene regulation in defined signalling pathways Nucleic acids research 2003;31 (23):e153 [PubMed]