Publications C.J. Aalbers
- Position
- Assistant Professor
- Main activities
- Research
- Specialisation
- Clinical immunology and rheumatology
- Focus of research
Local gene therapy for rheumatoid arthritis
Amsterdam UMC Research Institutes
AMC departments
All publications
2017
- Aalbers Caroline J., Broekstra Niels, van Geldorp Mariska, Kramer Emiel, Ramiro Sofia, Tak Paul P., Vervoordeldonk Margriet J., Finn Jonathan D. Empty Capsids and Macrophage Inhibition/Depletion Increase rAAV Transgene Expression in Joints of Both Healthy and Arthritic Mice Human gene therapy 2017;28 (2):168-178 [PubMed]
2015
- Aalbers Caroline Josephine Gene therapy for arthritis: progress towards a clinical trial 2015. 196p. ISBN 9789461826053. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Tak P. P.; Co-supervisor: Vervoordeldonk M. J. B. M.)
- Aalbers Caroline, Gerlag Danielle, Vos Koen, Vervoordeldonk Margriet, Landewé Robert, Tak Paul Peter Intra-articular etanercept treatment in inflammatory arthritis: A randomized double-blind placebo-controlled proof of mechanism clinical trial validating TNF as a potential therapeutic target for local treatment Joint, bone, spine 2015;82 (5):338-344 [PubMed]
- Aalbers Caroline J., Bevaart Lisette, Loiler Scott, de Cortie Karin, Wright J. Fraser, Mingozzi Federico, Tak Paul P., Vervoordeldonk Margriet J. Preclinical Potency and Biodistribution Studies of an AAV 5 Vector Expressing Human Interferon-β (ART-I02) for Local Treatment of Patients with Rheumatoid Arthritis PLoS ONE 2015;10 (6):e0130612 [PubMed]
- Bevaart Lisette, Aalbers Caroline J., Vierboom Michel P. M., Broekstra Niels, Kondova Ivanela, Breedveld Elia, Hauck Bernd, Wright J. Fraser, Tak Paul Peter, Vervoordeldonk Margriet J. Safety, Biodistribution, and Efficacy of an AAV-5 Vector Encoding Human Interferon-Beta (ART-I02) Delivered via Intra-Articular Injection in Rhesus Monkeys with Collagen-Induced Arthritis Human gene therapy. Clinical development 2015;26 (2):103-112 [PubMed]
- Aalbers Caroline J., Gerlag Danielle M., Vervoordeldonk Margriet J., Tak Paul P., Landewé Robert B. Single-joint Assessment for the Evaluation of Intraarticular Treatment: Responsiveness and Discrimination of the Composite Change Index Journal of rheumatology 2015;42 (9):1672-1676 [PubMed]
2011
- Aalbers Caroline J., Tak Paul P., Vervoordeldonk Margriet J. Advancements in adeno-associated viral gene therapy approaches: exploring a new horizon F1000 medicine reports 2011;3:17 [PubMed]
2010
- Aalbers Caroline J., Groen Justus L., Sivapalaratnam Suthesh More outreach for young scientists Nature 2010;467 (7314):401 [PubMed]
2009
- Vervoordeldonk Margriet J., Aalbers Caroline J., Tak Paul P. Interferon beta for rheumatoid arthritis: new clothes for an old kid on the block Annals of the rheumatic diseases 2009;68 (2):157-158 [PubMed]
2008
- Vervoordeldonk M. J. B. M., Aalbers Caroline J., Tak P. P. Advances in local targeted gene therapy for arthritis: towards clinical reality. Future rheumatology 2008;3 (4):307-309