E.E.J.M. Creemers PhD publications

2021

• Man Joyce C. K., van Duijvenboden Karel, Krijger Peter H. L., Hooijkaas Ingeborg B., van der Made Ingeborg, de Gier-de Vries Corrie, Wakker Vincent, Creemers Esther E., de Laat Wouter, Boukens Bastiaan J., Christoffels Vincent M. Genetic Dissection of a Super Enhancer Controlling the Nppa-Nppb Cluster in the Heart Circulation research 2021;128 (1):115-129 [PubMed]
• Singh Sandeep, de Ronde Maurice W. J., Creemers Esther E., van der Made Ingeborg, Meijering Roelien, Chan Mark Y., Hwee Tan Sock, Tang Chin Chee, Mark Richards A., Troughton Richard W., Yean Yip Fong Alan, Yan Bryan P., Pinto-Sietsma Sara-Joan Low miR-19b-1-5p Expression Is Related to Aspirin Resistance and Major Adverse Cardio- Cerebrovascular Events in Patients With Acute Coronary Syndrome Journal of the American Heart Association 2021;10 (2):e017120 [PubMed]
• Medzikovic Lejla, Heese Hylja, van Loenen Pieter B., van Roomen Cindy P. A. A., Hooijkaas Ingeborg B., Christoffels Vincent M., Creemers Esther E., de Vries Carlie J. M., de Waard Vivian Nuclear receptor nur77 controls cardiac fibrosis through distinct actions on fibroblasts and cardiomyocytes International journal of molecular sciences 2021;22 (4):1-16 [PubMed]

2020

• Aufiero Simona Characterization of the circRNome in the heart: A bioinformatic approach 2020. 159p. ISBN 9789402819205. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Pinto Yigal, Zwinderman A. H.; Co-supervisor: Creemers Esther E. J. M.)
• Aufiero Simona, Reckman Yolan J., Tijsen Anke J., Pinto Yigal M., Creemers Esther E. circRNAprofiler: an R-based computational framework for the downstream analysis of circular RNAs BMC bioinformatics 2020;21 (1):164 [PubMed]
• Rivaud Mathilde R., Marchal Gerard A., Wolswinkel Rianne, Jansen John A., van der Made Ingeborg, Beekman Leander, Ruiz-Villalba Adrián, Baartscheer Antonius, Rajamani Sridharan, Belardinelli Luiz, van Veen Toon A. B., Basso Cristina, Thiene Gaetano, Creemers Esther E., Bezzina Connie R., Remme Carol Ann Functional modulation of atrio-ventricular conduction by enhanced late sodium current and calcium-dependent mechanisms in Scn5a1798insD/+ mice EP Europace 2020;22 (10):1579-1589 [PubMed]
• de Groot N. E., van den Hoogenhof M. M. G., Najafi A., van der Made I., van der Velden J., Beqqali A., Pinto Y. M., Creemers E. E. Heterozygous loss of Rbm24 in the adult mouse heart increases sarcomere slack length but does not affect function Scientific reports 2020;10 (1):7687 [PubMed]
• Singh Sandeep, de Ronde Maurice W J, Kok Maayke G M, Beijk Marcel Am, De Winter Robbert J, van der Wal Allard C, Sondermeijer Brigitte M, Meijers Joost C M, Creemers Esther E, Pinto-Sietsma Sara-Joan MiR-223-3p and miR-122-5p as circulating biomarkers for plaque instability Open heart 2020;7 (1) [PubMed]

2019

• Aufiero Simona, Reckman Yolan J., Pinto Yigal M., Creemers Esther E. Circular RNAs open a new chapter in cardiovascular biology Nature reviews. Cardiology 2019;16 (8):503–514 [PubMed]
• van Duijvenboden Karel, de Bakker Dennis E. M., Man Joyce C. K., Janssen Rob, Günthel Marie, Hill Matthew C., Hooijkaas Ingeborg B., van der Made Ingeborg, van der Kraak Petra H., Vink Aryan, Creemers Esther E., Martin James F., Barnett Phil, Bakkers Jeroen, Christoffels Vincent M. Conserved NPPB+ Border Zone Switches From MEF2- to AP-1-Driven Gene Program Circulation 2019;140 (10):864-879 [PubMed]
• Houweling Arjan C., Beaman Glenda M., Postma Alex V., Blair Gainous T., Lichtenbelt Klaske D., Brancati Francesco, Lopes Filipa M., van der Made Ingeborg, Polstra Abeltje M., Robinson Michael L., Wright Kevin D., Ellingford Jamie M., Jackson Ashley R., Overwater Eline, Genesio Rita, Romano Silvio, Camerota Letizia, D'Angelo Emanuela, Meijers-Heijboer Elizabeth J., Christoffels Vincent M., McHugh Kirk M., Black Brian L., Newman William G., Woolf Adrian S., Creemers Esther E. Loss-of-function variants in myocardin cause congenital megabladder in humans and mice Journal of clinical investigation 2019;129 (12):5374-5380 [PubMed]

2018

• van den Hoogenhof Maarten M. G., van der Made Ingeborg, de Groot Nina E., Damanafshan Amin, van Amersfoorth Shirley C. M., Zentilin Lorena, Giacca Mauro, Pinto Yigal M., Creemers Esther E. AAV9-mediated Rbm24 overexpression induces fibrosis in the mouse heart Scientific reports 2018;8 (1) [PubMed]
• Rivaud Mathilde R., Jansen John A., Postema Pieter G., Nannenberg Eline A., Mizusawa Yuka, van der Nagel Roel, Wolswinkel Rianne, van der Made Ingeborg, Marchal Gerard A., Rajamani Sridharan, Belardinelli Luiz, van Tintelen J. Peter, Tanck Michael W. T., van DerWal Allard C., de Bakker Jacques M. T., van Rijen Harold V., Creemers Esther E., Wilde Arthur A. M., van den Berg Maarten P., van Veen Toon A. B., Bezzina Connie R., Remme Carol Ann A common co-morbiditymodulates disease expression and treatment efficacy in inherited cardiac sodiumchannelopathy European heart journal 2018;39 (31):2898-2907 [PubMed]
• Aufiero Simona, van den Hoogenhof Maarten M. G., Reckman Yolan J., Beqqali Abdelaziz, van der Made Ingeborg, Kluin Jolanda, Khan Mohsin A. F., Pinto Yigal M., Creemers Esther E. Cardiac circRNAs arise mainly from constitutive exons rather than alternatively spliced exons RNA (New York, N.Y.) 2018;24 (6):815-827 [PubMed]
• Gomes Clarissa P C, Salgado-Somoza Antonio, Creemers Esther E, Dieterich Christoph, Lustrek Mitja, Devaux Yvan Circular RNAs in the cardiovascular system Non-coding RNA research 2018;3 (1):1-11 [PubMed]
• Reckman Yolan J., Creemers Esther E. Circulating Circles Predict Postoperative Atrial Fibrillation Journal of the American Heart Association 2018;7 (2) [PubMed]
• de Ronde Maurice W. J. Circulating microRNAs: Methodological solutions to identify biomarkers for cardiovascular disease 2018. ISBN 9789462998476. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Meijers J. C. M.; Co-supervisors: Pinto-Sietsma S. J., Creemers E. E. J. M.)
• Rivaud Mathilde Diversity and complexity of cardiac sodium channel (dys)function: Relevance for arrhythmias in inherited and acquired diseases 2018. ISBN 9789402810233. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Bezzina C. R.; Co-supervisors: Remme C. A., Creemers E. E. J. M.)
• Medzikovic Lejla, van Roomen Cindy, Baartscheer Antonius, van Loenen Pieter B, de Vos Judith, Bakker Erik N T P, Koenis Duco S, Damanafshan Amin, Creemers Esther E, Arkenbout E Karin, de Vries Carlie J M, de Waard Vivian Nur77 protects against adverse cardiac remodelling by limiting neuropeptide Y signalling in the sympathoadrenal-cardiac axis Cardiovascular research 2018;114 (12):1617-1628 [PubMed]
• van den Hoogenhof Maarten M. G., Beqqali Abdelaziz, Amin Ahmad S., van der Made Ingeborg, Aufiero Simona, Khan Mohsin A. F., Schumacher Cees A., Jansweijer Joeri A., van Spaendonck-Zwarts Karin Y., Remme Carol Ann, Backs Johannes, Verkerk Arie O., Baartscheer Antonius, Pinto Yigal M., Creemers Esther E. RBM20 Mutations Induce an Arrhythmogenic Dilated Cardiomyopathy Related to Disturbed Calcium Handling Circulation 2018;138 (13):1330-1342 [PubMed]
• van den Hoogenhof Maarten M. G. RNA splicing in the heart: Changing parts and performance 2018. ISBN 9789402809534. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Pinto Y. M.; Co-supervisor: Creemers E. E. J. M.)
• Kok M. G. M., de Ronde M. W. J., Moerland P. D., Ruijter J. M., Creemers E. E., Pinto-Sietsma S. J. Small sample sizes in high-throughput miRNA screens: A common pitfall for the identification of miRNA biomarkers Biomolecular Detection and Quantification 2018;15:1-5 [PubMed]
• de Ronde Maurice W. J., Ruijter Jan M., Moerland Perry D., Creemers Esther E., Pinto-Sietsma Sara-Joan Study design and qPCR data analysis guidelines for reliable circulating miRNA biomarker experiments: A review Clinical chemistry 2018;64 (9):1308-1318 [PubMed]

2017

• Devaux Yvan, Creemers Esther E., Boon Reinier A., Werfel Stanislas, Thum Thomas, Engelhardt Stefan, Dimmeler Stefanie, Squire Iain Circular RNAs in heart failure European journal of heart failure 2017;19 (6):701-709 [PubMed]
• de Ronde Maurice W. J., Kok Maayke G. M., Moerland Perry D., van den Bossche Jan, Neele Annette E., Halliani Amalia, van der Made Ingeborg, de Winther Menno P. J., Meijers Joost C. M., Creemers Esther E., Pinto-Sietsma Sara-Joan High miR-124-3p expression identifies smoking individuals susceptible to atherosclerosis Atherosclerosis 2017;263:377-384 [PubMed]
• Nakagawa Yasuaki, Nishikimi Toshio, Kuwahara Koichiro, Fujishima Aoi, Oka Shogo, Tsutamoto Takayoshi, Kinoshita Hideyuki, Nakao Kazuhiro, Cho Kosai, Inazumi Hideaki, Okamoto Hiroyuki, Nishida Motohiro, Kato Takao, Fukushima Hiroyuki, Yamashita Jun K., Wijnen Wino J., Creemers Esther E., Kangawa Kenji, Minamino Naoto, Nakao Kazuwa, Kimura Takeshi MiR30-GALNT1/2 Axis-Mediated Glycosylation Contributes to the Increased Secretion of Inactive Human Prohormone for Brain Natriuretic Peptide (proBNP) From Failing Hearts Journal of the American Heart Association 2017;6 (2) [PubMed]
• Heinig Matthias, Adriaens Michiel E., Schafer Sebastian, van Deutekom Hanneke W. M., Lodder Elisabeth M., Ware James S., Schneider Valentin, Felkin Leanne E., Creemers Esther E., Meder Benjamin, Katus Hugo A., Rühle Frank, Stoll Monika, Cambien François, Villard Eric, Charron Philippe, Varro Andras, Bishopric Nanette H., George Alfred L., Dos Remedios Cristobal, Moreno-Moral Aida, Pesce Francesco, Bauerfeind Anja, Rüschendorf Franz, Rintisch Carola, Petretto Enrico, Barton Paul J., Cook Stuart A., Pinto Yigal M., Bezzina Connie R., Hubner Norbert Natural genetic variation of the cardiac transcriptome in non-diseased donors and patients with dilated cardiomyopathy Genome biology 2017;18 (1) [PubMed]
• de Ronde Maurice W. J., Ruijter Jan M., Lanfear David, Bayes-Genis Antoni, Kok Maayke G. M., Creemers Esther E., Pinto Yigal M., Pinto-Sietsma Sara-Joan Practical data handling pipeline improves performance of qPCR-based circulating miRNA measurements RNA (New York, N.Y.) 2017;23 (5):811-821 [PubMed]
• Tijsen A. J., Pinto Y. M., Creemers E. E. The Clinical Potential of Heart Failure-Related miRNAsin: Translating MicroRNAs to the Clinic. Elsevier Inc.; 2017. p. 283-328, ISBN 9780128005538
• van den Hoogenhof Maarten M. G., van der Made Ingeborg, Beqqali Abdelaziz, de Groot Nina E., Damanafshan Amin, van Oort Ralph J., Pinto Yigal M., Creemers Esther E. The RNA-binding protein Rbm38 is dispensable during pressure overload-induced cardiac remodeling in mice PLoS ONE 2017;12 (8) [PubMed]
• McDermott-Roe Chris, Leleu Marion, Rowe Glenn C., Palygin Oleg, Bukowy John D., Kuo Judy, Rech Monika, Hermans-Beijnsberger Steffie, Schaefer Sebastian, Adami Eleonora, Creemers Esther E., Heinig Matthias, Schroen Blanche, Arany Zoltan, Petretto Enrico, Geurts Aron M. Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function PLoS ONE 2017;12 (2) [PubMed]
• van Eldik Willemijn, den Adel Brigit, Monshouwer-Kloots Jantine, Salvatori Daniela, Maas Saskia, van der Made Ingeborg, Creemers Esther E., Frank Derk, Frey Norbert, Boontje Nicky, van der Velden Jolanda, Steendijk Paul, Mummery Christine, Passier Robert, Beqqali Abdelaziz Z-disc protein CHAPb induces cardiomyopathy and contractile dysfunction in the postnatal heart PLoS ONE 2017;12 (12) [PubMed]

2016

• Beqqali Abdelaziz, Bollen Ilse A. E., Rasmussen Torsten B., van den Hoogenhof Maarten M., van Deutekom Hanneke W. M., Schafer Sebastian, Haas Jan, Meder Benjamin, Sørensen Keld E., van Oort Ralph J., Mogensen Jens, Hubner Norbert, Creemers Esther E., van der Velden Jolanda, Pinto Yigal M. A mutation in the glutamate-rich region of RNA-binding motif protein 20 causes dilated cardiomyopathy through missplicing of titin and impaired Frank-Starling mechanism Cardiovascular research 2016;112 (1):452-463 [PubMed]
• Creemers Esther E., van Rooij Eva Function and Therapeutic Potential of Noncoding RNAs in Cardiac Fibrosis Circulation research 2016;118 (1):108-118 [PubMed]
• Creemers Esther E., Bawazeer Amira, Ugalde Alejandro P., van Deutekom Hanneke W. M., van der Made Ingeborg, de Groot Nina E., Adriaens Michiel E., Cook Stuart A., Bezzina Connie R., Hubner Norbert, van der Velden Jolanda, Elkon Ran, Agami Reuven, Pinto Yigal M. Genome-Wide Polyadenylation Maps Reveal Dynamic mRNA 3'-End Formation in the Failing Human Heart Circulation research 2016;118 (3):433-438 [PubMed]
• Sergeeva Irina A., Hooijkaas Ingeborg B., Ruijter Jan M., van der Made Ingeborg, de Groot Nina E., van de Werken Harmen J. G., Creemers Esther E., Christoffels Vincent M. Identification of a regulatory domain controlling the Nppa-Nppb gene cluster during heart development and stress Development (Cambridge, England) 2016;143 (12):2135-2146 [PubMed]
• Kok M. G. M., Mandolini C., Moerland P. D., de Ronde M. W. J., Sondermeijer B. M., Halliani A., Nieuwland R., Cipollone F., Creemers E. E., Meijers J. C. M., Pinto-Sietsma S. J. Low miR-19b-1-5p expression in isolated platelets after aspirin use is related to aspirin insensitivity International journal of cardiology 2016;203:262-263 [PubMed]
• Khan Mohsin A. F., Reckman Yolan J., Aufiero Simona, van den Hoogenhof Maarten M. G., van der Made Ingeborg, Beqqali Abdelaziz, Koolbergen Dave R., Rasmussen Torsten B., van der Velden Jolanda, Creemers Esther E., Pinto Yigal M. RBM20 Regulates Circular RNA Production From the Titin Gene Circulation research 2016;119 (9):996-1003 [PubMed]
• van den Hoogenhof Maarten M. G., Pinto Yigal M., Creemers Esther E. RNA Splicing: Regulation and Dysregulation in the Heart Circulation research 2016;118 (3):454-468 [PubMed]

2015

• Kok Maayke Guda Maria Circulating microRNAs and other biomarkers for premature atherosclerosis 2015. 141p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Meijers J. C. M.; Co-supervisors: Pinto-Sietsma S. J., Creemers E. E.)
• Weeland Cornelis J., van den Hoogenhof Maarten M., Beqqali Abdelaziz, Creemers Esther E. Insights into alternative splicing of sarcomeric genes in the heart Journal of molecular and cellular cardiology 2015;81:107-113 [PubMed]
• Devaux Yvan, Zangrando Jennifer, Schroen Blanche, Creemers Esther E., Pedrazzini Thierry, Chang Ching-Pin, Dorn Gerald W., Thum Thomas, Heymans Stephane Long noncoding RNAs in cardiac development and ageing Nature reviews. Cardiology 2015;12 (7):415-425 [PubMed]
• Kok Maayke G. M., Halliani Amalia, Moerland Perry D., Meijers Joost C. M., Creemers Esther E., Pinto-Sietsma Sara-Joan Normalization panels for the reliable quantification of circulating microRNAs by RT-qPCR FASEB journal 2015;29 (9):3853-3862 [PubMed]
• Medzikovic Lejla, Schumacher Cees A., Verkerk Arie O., van Deel Elza D., Wolswinkel Rianne, van der Made Ingeborg, Bleeker Natascha, Cakici Daniella, van den Hoogenhof Maarten M. G., Meggouh Farid, Creemers Esther E., Remme Carol Ann, Baartscheer Antonius, de Winter Robbert J., de Vries Carlie J. M., Arkenbout E. Karin, de Waard Vivian Orphan nuclear receptor Nur77 affects cardiomyocyte calcium homeostasis and adverse cardiac remodelling Scientific reports 2015;5:15404 [PubMed]
• Wijnen Winandus Johannes Regulation of cardiac form and function: small RNAs and large hearts 2015. 138p. ISBN 9789462596672. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Pinto Y. M.; Co-supervisor: Creemers E. E. J. M.)

2014

• Sergeeva Irina A., Hooijkaas Ingeborg B., van der Made Ingeborg, Jong Willeke M. C., Creemers Esther E., Christoffels Vincent M. A transgenic mouse model for the simultaneous monitoring of ANF and BNP gene activity during heart development and disease Cardiovascular research 2014;101 (1):78-86 [PubMed]
• Wijnen Wino J., van der Made Ingeborg, van den Oever Stephanie, Hiller Monika, de Boer Bouke A., Picavet Daisy I., Chatzispyrou Iliana A., Houtkooper Riekelt H., Tijsen Anke J., Hagoort Jaco, van Veen Henk, Everts Vincent, Ruijter Jan M., Pinto Yigal M., Creemers Esther E. Cardiomyocyte-specific miRNA-30c over-expression causes dilated cardiomyopathy PLoS ONE 2014;9 (5):e96290 [PubMed]
• Martin-Ramirez Javier, Kok Maayke G. M., Hofman Menno, Bierings Ruben, Creemers Esther E., Meijers Joost C. M., Voorberg Jan, Pinto-Sietsma Sara-Joan Individual with subclinical atherosclerosis have impaired proliferation of blood outgrowth endothelial cells, which can be restored by statin therapy PLoS ONE 2014;9 (6):e99890 [PubMed]
• Fan Dong, Creemers Esther E., Kassiri Zamaneh Matrix as an Interstitial Transport System Circulation research 2014;114 (5):889-902 [PubMed]
• Tijsen Anke J., van der Made Ingeborg, van den Hoogenhof Maarten M., Wijnen Wino J., van Deel Elza D., de Groot Nina E., Alekseev Sergey, Fluiter Kees, Schroen Blanche, Goumans Marie-José, van der Velden Jolanda, Duncker Dirk J., Pinto Yigal M., Creemers Esther E. The microRNA-15 family inhibits the TGFβ-pathway in the heart Cardiovascular research 2014;104 (1):61-71 [PubMed]

2013

• Heymans Stephane, Corsten Maarten F., Verhesen Wouter, Carai Paolo, van Leeuwen Rick E. W., Custers Kevin, Peters Tim, Hazebroek Mark, Stöger Lauran, Wijnands Erwin, Janssen Ben J., Creemers Esther E., Pinto Yigal M., Grimm Dirk, Schürmann Nina, Vigorito Elena, Thum Thomas, Stassen Frank, Yin Xiaoke, Mayr Manuel, de Windt Leon J., Lutgens Esther, Wouters Kristiaan, de Winther Menno P. J., Zacchigna Serena, Giacca Mauro, van Bilsen Marc, Papageorgiou Anna-Pia, Schroen Blanche Macrophage microRNA-155 promotes cardiac hypertrophy and failure Circulation 2013;128 (13):1420-1432 [PubMed]
• Tijsen Anke J. M. MicroRNAs in cardiac diseases. The devil is in the details 2013. 291p. ISBN 9789461918581. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Pinto Y. M.; Co-supervisor: Creemers E. E. J. M.)
• Wijnen Wino J., Pinto Yigal M., Creemers Esther E. The therapeutic potential of miRNAs in cardiac fibrosis: where do we stand? Journal of cardiovascular translational research 2013;6 (6):899-908 [PubMed]

2012

• Tijsen Anke J., Pinto Yigal M., Creemers Esther E. Circulating microRNAs as diagnostic biomarkers for cardiovascular diseases American journal of physiology. Heart and circulatory physiology 2012;303 (9):H1085-H1095 [PubMed]
• Creemers Esther E., Tijsen Anke J., Pinto Yigal M. Circulating MicroRNAs Novel Biomarkers and Extracellular Communicators in Cardiovascular Disease? Circulation research 2012;110 (3):483-495 [PubMed]
• Mokalled Mayssa H., Johnson Aaron N., Creemers Esther E., Olson Eric N. MASTR directs MyoD-dependent satellite cell differentiation during skeletal muscle regeneration Genes & development 2012;26 (2):190-202 [PubMed]
• Sivapalaratnam Suthesh, Basart Hanneke, Watkins Nicholas A., Maiwald Stepanie, Rendon Augusto, Krishnan Unni, Sondermeijer Brigitte M., Creemers Esther E., Pinto-Sietsma Sara J., Hovingh Kees, Ouwehand Willem H., Kastelein John J. P., Goodall Alison H., Trip Mieke D. Monocyte Gene Expression Signature of Patients with Early Onset Coronary Artery Disease PLoS ONE 2012;7 (2):e32166 [PubMed]
• Tijsen Anke J., Pinto Yigal M., Creemers Esther E. Non-cardiomyocyte microRNAs in heart failure Cardiovascular research 2012;93 (4):573-582 [PubMed]
• Leenders Joost J., Wijnen Wino J., van der Made Ingeborg, Hiller Monika, Swinnen Melissa, VandenDriessche Thierry, Chuah Marinee, Pinto Yigal M., Creemers Esther E. Repression of Cardiac Hypertrophy by KLF15: Underlying Mechanisms and Therapeutic Implications PLoS ONE 2012;7 (5):e36754 [PubMed]
• Leenders Joost J. G. Three fingers on the brake. Kruppel-like factor 15, a repressor of cardiac gene expression 2012. 189p. ISBN 9789461912718. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Pinto Y. M.; Co-supervisor: Creemers E. E. J. M.)
• Amin Ahmad S., Giudicessi John R., Tijsen Anke J., Spanjaart Anne M., Reckman Yolan J., Klemens Christine A., Tanck Michael W., Kapplinger Jamie D., Hofman Nynke, Sinner Moritz F., Müller Martina, Wijnen Wino J., Tan Hanno L., Bezzina Connie R., Creemers Esther E., Wilde Arthur A. M., Ackerman Michael J., Pinto Yigal M. Variants in the 3 untranslated region of the KCNQ1-encoded K(v)7.1 potassium channel modify disease severity in patients with type 1 long QT syndrome in an allele-specific manner European heart journal 2012;33 (6):714-723 [PubMed]

2011

• Creemers Esther E., Wilde Arthur A., Pinto Yigal M. Heart failure: advances through genomics Nature reviews. Genetics 2011;12 (5):357-362 [PubMed]
• Creemers Esther E., Pinto Yigal M. Molecular mechanisms that control interstitial fibrosis in the pressure-overloaded heart Cardiovascular research 2011;89 (2):265-272 [PubMed]
• Sondermeijer Brigitte M., Bakker Annemieke, Halliani Amalia, de Ronde Maurice W. J., Marquart Arnoud A., Tijsen Anke J., Mulders Ties A., Kok Maayke G. M., Battjes Suzanne, Maiwald Steffi, Sivapalaratnam Suthesh, Trip Mieke D., Moerland Perry D., Meijers Joost C. M., Creemers Esther E., Pinto-Sietsma Sara-Joan Platelets in patients with premature coronary artery disease exhibit upregulation of miRNA340* and miRNA624* PLoS ONE 2011;6 (10):e25946 [PubMed]
• Leenders Joost J., Pinto Yigal M., Creemers Esther E. Tapping the brake on cardiac growth-endogenous repressors of hypertrophic signaling Journal of molecular and cellular cardiology 2011;51 (2):156-167 [PubMed]

2010

• Tijsen Anke J., Creemers Esther E., Moerland Perry D., Pinto Yigal M. MicroRNAs As Circulating Biomarkers for Heart Failure: Questions About MiR-423-5p Response Circulation research 2010;106 (9):E9
• Tijsen Anke J., Creemers Esther E., Moerland Perry D., de Windt Leon J., van der Wal Allard C., Kok Wouter E., Pinto Yigal M. MiR423-5p As a Circulating Biomarker for Heart Failure Circulation research 2010;106 (6):1035-U63 [PubMed]
• Leenders Joost J., Wijnen Wino J., Hiller Monika, van der Made Inge, Lentink Viola, van Leeuwen Rick E., Herias Veronica, Pokharel Saraswati, Heymans Stephane, de Windt Leon J., Hoydal Morten A., Pinto Yigal M., Creemers Esther E. Regulation of Cardiac Gene Expression by KLF15, a Repressor of Myocardin Activity Journal of biological chemistry 2010;285 (35):27449-27456 [PubMed]

2009

• van den Borne Susanne W. M., Cleutjens Jack P. M., Hanemaaijer Roeland, Creemers Esther E., Smits Jos F. M., Daemen Mat J. A. P., Blankesteijn W. Matthijs Increased matrix metalloproteinase-8 and -9 activity in patients with infarct rupture after myocardial infarction Cardiovascular pathology 2009;18 (1):37-43 [PubMed]
• Duisters Rudy F., Tijsen Anke J., Schroen Blanche, Leenders Joost J., Lentink Viola, van der Made Ingeborg, Herias Veronica, van Leeuwen Rick E., Schellings Mark W., Barenbrug Paul, Maessen Jos G., Heymans Stephane, Pinto Yigal M., Creemers Esther E. miR-133 and miR-30 Regulate Connective Tissue Growth Factor Implications for a Role of MicroRNAs in Myocardial Matrix Remodeling Circulation research 2009;104 (2):170-U61 [PubMed]

2008

• French Wendy J., Creemers Esther E., Tallquist Michelle D. Platelet-derived growth factor receptors direct vascular development independent of vascular smooth muscle cell function Molecular and cellular biology 2008;28 (18):5646-5657 [PubMed]

2007

• Long Xiaochun, Creemers Esther E., Wang Da-Zhi, Olson Eric N., Miano Joseph M. Myocardin is a bifunctional switch for smooth versus skeletal muscle differentiation Proceedings of the National Academy of Sciences of the United States of America 2007;104 (42):16570-16575 [PubMed]

2006

• Creemers Esther E., Sutherland Lillian B., Oh Jiyeon, Barbosa Ana C., Olson Eric N. Coactivation of MEF2 by the SAP domain proteins myocardin and MASTR Molecular cell 2006;23 (1):83-96 [PubMed]
• Creemers Esther E., Sutherland Lillian B., McAnally John, Richardson James A., Olson Eric N. Myocardin is a direct transcriptional target of Mef2, Tead and Foxo proteins during cardiovascular development Development (Cambridge, England) 2006;133 (21):4245-4256 [PubMed]
• Pipes G. C. Teg, Creemers Esther E., Olson Eric N. The myocardin family of transcriptional coactivators: versatile regulators of cell growth, migration, and myogenesis Genes & development 2006;20 (12):1545-1556 [PubMed]

2005

• Pipes G. C. Teg, Sinha Sanjay, Qi Xiaoxia, Zhu Chun-Hong, Gallardo Teresa D., Shelton John, Creemers Esther E., Sutherland Lillian, Richardson James A., Garry Daniel J., Wright Woodring E., Owens Gary K., Olson Eric N. Stem cells and their derivatives can bypass the requirement of myocardin for smooth muscle gene expression Developmental biology 2005;288 (2):502-513 [PubMed]

2003

• Creemers Esther E. J. M., Davis Jeniffer N., Parkhurst Andrea M., Leenders Peter, Dowdy Kathryn B., Hapke Elizabeth, Hauet Anne M., Escobar Patricia G., Cleutjens Jack P. M., Smits Jos F. M., Daemen Mat J. A. P., Zile Michael R., Spinale Francis G. Deficiency of TIMP-1 exacerbates LV remodeling after myocardial infarction in mice American journal of physiology. Heart and circulatory physiology 2003;284 (1):H364-H371 [PubMed]
• Heeneman Sylvia, Cleutjens Jack P., Faber Birgit C., Creemers Esther E., van Suylen Robert-Jan, Lutgens Esther, Cleutjens Kitty B., Daemen Mat J. The dynamic extracellular matrix: intervention strategies during heart failure and atherosclerosis Journal of pathology 2003;200 (4):516-525 [PubMed]

2002

• Cleutjens Jack P. M., Creemers Esther E. J. M. Integration of concepts: cardiac extracellular matrix remodeling after myocardial infarction Journal of cardiac failure 2002;8 (6 Suppl):S344-S348 [PubMed]

2001

• Blankesteijn W. M., Creemers E., Lutgens E., Cleutjens J. P., Daemen M. J., Smits J. F. Dynamics of cardiac wound healing following myocardial infarction: observations in genetically altered mice Acta physiologica Scandinavica 2001;173 (1):75-82 [PubMed]
• Creemers E. E., Cleutjens J. P., Smits J. F., Daemen M. J. Matrix metalloproteinase inhibition after myocardial infarction: a new approach to prevent heart failure? Circulation research 2001;89 (3):201-210 [PubMed]

2000

• Creemers E., Cleutjens J., Smits J., Heymans S., Moons L., Collen D., Daemen M., Carmeliet P. Disruption of the plasminogen gene in mice abolishes wound healing after myocardial infarction American journal of pathology 2000;156 (6):1865-1873 [PubMed]

1999

• Heymans S., Luttun A., Nuyens D., Theilmeier G., Creemers E., Moons L., Dyspersin G. D., Cleutjens J. P., Shipley M., Angellilo A., Levi M. [=Marcel M.], Nübe O., Baker A., Keshet E., Lupu F., Herbert J. M., Smits J. F., Shapiro S. D., Baes M., Borgers M., Collen D., Daemen M. J., Carmeliet P. Inhibition of plasminogen activators or matrix metalloproteinases prevents cardiac rupture but impairs therapeutic angiogenesis and causes cardiac failure Nature medicine 1999;5 (10):1135-1142 [PubMed]