Publications MSc G. de Wilde
- Position
- PhD Candidate
- Main activities
- Research
- Specialisation
- B-cell neoplasms, Multiple Myeloma.
- Focus of research
In our lab, we study a diverse range of topics, pertaining to B cell biology, the role of DNA Damage Repair (DDR) systems in lymphomagenesis and Multiple Myeloma. My project specifically focuses on translational research in Multiple Myeloma. Our goal is to unravel key metabolic processes in Myeloma with the eventual aim to exploit the metabolic vulnerabilities in these cells for therapeutic benefit.
Amsterdam UMC Research Institutes
AMC departments
All publications
2021
- Bloedjes Timon A., de Wilde Guus, Guikema Jeroen E. J. Metabolic effects of recurrent genetic aberrations in multiple myeloma Cancers 2021;13 (3):1-36 [PubMed]
2019
- Bahjat Mahnoush, de Wilde Guus, van Dam Tijmen, Maas Chiel, Bloedjes Timon, Bende Richard J, van Noesel Carel J M, Luijks Dieuwertje M, Eldering Eric, Kersten Marie José, Guikema Jeroen E J The NEDD8-activating enzyme inhibitor MLN4924 induces DNA damage in Ph+ leukemia and sensitizes for ABL kinase inhibitors Cell cycle (Georgetown, Tex.) 2019;18 (18):2307-2322 [PubMed]