Publications MSc J.A.C. van Bruggen
- Position
- PhD Candidate
- Main activities
- Research
- Specialisation
- T cell metabolism
- Focus of research
Investigating whether improving T cell metabolism in CLL can improve efficacy of Chimeric Antigen Receptor therapy.
Amsterdam UMC Research Institutes
AMC departments
All publications
2020
- Hofland Tom, Martens Anne W. J., van Bruggen Jaco A. C., de Boer Renate, Schetters Sjoerd, Remmerswaal Ester B. M., Bemelman Frederike J., Levin Mark-David, Bins Adriaan D., Eldering Eric, Kater Arnon P., Tonino Sanne H. Human CXCR5+PD-1+ CD8 T cells in healthy individuals and patients with hematologic malignancies European journal of immunology 2020 [PubMed]
- van Bruggen Jaco A. C., Martens Anne W. J., Tonino Sanne H., Kater Arnon P. Overcoming the hurdles of autologous t‐cell‐based therapies in b‐cell non‐hodgkin lymphoma Cancers 2020;12 (12):1-31 [PubMed]
2019
- van Bruggen Jaco A. C., Martens Anne W. J., Fraietta Joseph A., Hofland Tom, Tonino Sanne H., Eldering Eric, Levin Mark-David, Siska Peter J., Endstra Sanne, Rathmell Jeffrey C., June Carl H., Porter David L., Melenhorst J. Joseph, Kater Arnon P., van der Windt Gerritje J. W. Chronic lymphocytic leukemia cells impair mitochondrial fitness in CD8+ T cells and impede CAR T-cell efficacy Blood 2019;134 (1):44-58 [PubMed]
- van der Schoot Johan M. S., Fennemann Felix L., Valente Michael, Dolen Yusuf, Hagemans Iris M., Becker Anouk M. D., le Gall Camille M., van Dalen Duco, Cevirgel Alper, van Bruggen Jaco A. C., Engelfriet Melanie, Caval Tomislav, Bentlage Arthur E. H., Fransen Marieke F., Nederend Maaike, Leusen Jeanette H. W., Heck Albert J. R., Vidarsson Gestur, Figdor Carl G., Verdoes Martijn, Scheeren Ferenc A. Functional diversification of hybridoma-produced antibodies by CRISPR/HDR genomic engineering Science advances 2019;5 (8) [PubMed]
2017
- van Attekum Martijn H. A., van Bruggen Jaco A. C., Slinger Erik, Lebre M. Cristina, Reinen Emilie, Kersting Sabina, Eldering Eric, Kater Arnon P. CD40 signaling instructs chronic lymphocytic leukemia cells to attract monocytes via the CCR2 axis Haematologica 2017;102 (12):2069-2076 [PubMed]
2016
- van der Schaar H. M., Melia C. E., van Bruggen J. A. C., Strating J. R. P. M., van Geenen M. E. D., Koster A. J., Bárcena M., van Kuppeveld F. J. M. Illuminating the Sites of Enterovirus Replication in Living Cells by Using a Split-GFP-Tagged Viral Protein mSphere 2016;1 (4):e00104-16 [PubMed]