J.G.M. van Scheppingen PhD publications

2020

• Bongaarts Anika, de Jong Jody M., Broekaart Diede W. M., van Scheppingen Jackelien, Anink Jasper J., Mijnsbergen Caroline, Jansen Floor E., Spliet Wim G. M., den Dunnen Wilfred F. A., Gruber Victoria E., Scholl Theresa, Hainfellner Johannes A., Feucht Martha, Borkowska Julita, Kotulska Katarzyna, Jozwiak Sergiusz, Grajkowska Wieslawa, Buccoliero Anna Maria, Caporalini Chiara, Giordano Flavio, Genitori Lorenzo, Scicluna Brendon P., Schouten-van Meeteren Antoinette Y. N., van Vliet Erwin A., Mühlebner Angelika, Mills James D., Aronica Eleonora Dysregulation of the MMP/TIMP Proteolytic System in Subependymal Giant Cell Astrocytomas in Patients With Tuberous Sclerosis Complex: Modulation of MMP by MicroRNA-320d In Vitro Journal of neuropathology and experimental neurology 2020;79 (7):777-790 [PubMed]
• Korotkov Anatoly, Puhakka Noora, Gupta Shalini Das, Vuokila Niina, Broekaart Diede W. M., Anink Jasper J., Heiskanen Mette, Karttunen Jenni, van Scheppingen Jackelien, Huitinga Inge, Mills James D., van Vliet Erwin A., Pitkänen Asla, Aronica Eleonora Increased expression of miR142 and miR155 in glial and immune cells after traumatic brain injury may contribute to neuroinflammation via astrocyte activation Brain pathology (Zurich, Switzerland) 2020;30 (5):897-912 [PubMed]
• Broekaart D. W. M., van Scheppingen J., Anink J. J., Wierts L., van het Hof B., Jansen F. E., Spliet W. G., van Rijen P. C., Kamphuis W. W., de Vries H. E., Aronica E., van Vliet E. A. Increased matrix metalloproteinases expression in tuberous sclerosis complex: modulation by microRNA 146a and 147b in vitro Neuropathology and applied neurobiology 2020;46 (2):142-159 [PubMed]
• Korotkov Anatoly, Broekaart Diede W. M., Banchaewa Leyla, Pustjens Ben, van Scheppingen Jackelien, Anink Jasper J., Baayen Johannes C., Idema Sander, Gorter Jan A., van Vliet Erwin A., Aronica Eleonora microRNA-132 is overexpressed in glia in temporal lobe epilepsy and reduces the expression of pro-epileptogenic factors in human cultured astrocytes Glia 2020;68 (1):60-75 [PubMed]
• Mühlebner Angelika, van Scheppingen Jackelien, de Neef Andrew, Bongaarts Anika, Zimmer Till S., Mills James D., Jansen Floor E., Spliet Wim G. M., Krsek Pavel, Zamecnik Josef, Coras Roland, Blumcke Ingmar, Feucht Martha, Scholl Theresa, Gruber Victoria-Elisabeth, Hainfellner Johannes A., Söylemezoğlu Figen, Kotulska Katarzyna, Lagae Lieven, Jansen Anna C., Kwiatkowski David J., Jozwiak Sergiusz, Curatolo Paolo, Aronica Eleonora Myelin Pathology Beyond White Matter in Tuberous Sclerosis Complex (TSC) Cortical Tubers Journal of neuropathology and experimental neurology 2020;79 (10):1054-1064 [PubMed]

2019

• Veersema Tim J., de Neef Andrew, van Scheppingen Jackelien, Ferrier Cyrille H., van Eijsden Pieter, Gosselaar Peter H., van Rijen Peter C., Spliet Wim G. M., Braun Kees P. J., Mühlebner Angelika, Aronica Eleonora Changes in vascular density in resected tissue of 97 patients with mild malformation of cortical development, focal cortical dysplasia or TSC-related cortical tubers International journal of developmental neuroscience 2019;79:96-104 [PubMed]
• Arena Andrea, Zimmer Till S., van Scheppingen Jackelien, Korotkov Anatoly, Anink Jasper J., Mühlebner Angelika, Jansen Floor E., van Hecke Wim, Spliet Wim G., van Rijen Peter C., Vezzani Annamaria, Baayen Johannes C., Idema Sander, Iyer Anand M., Perluigi Marzia, Mills James D., van Vliet Erwin A., Aronica Eleonora Oxidative stress and inflammation in a spectrum of epileptogenic cortical malformations: molecular insights into their interdependence Brain pathology (Zurich, Switzerland) 2019;29 (3):351-365 [PubMed]
• Bongaarts Anika, van Scheppingen Jackelien, Korotkov Anatoly, Mijnsbergen Caroline, Anink Jasper J., Jansen Floor E., Spliet Wim G. M., den Dunnen Wilfred F. A., Gruber Victoria E., Scholl Theresa, Samueli Sharon, Hainfellner Johannes A., Feucht Martha, Kotulska Katarzyna, Jozwiak Sergiusz, Grajkowska Wieslawa, Buccoliero Anna Maria, Caporalini Chiara, Giordano Flavio, Genitori Lorenzo, Coras Roland, Blümcke Ingmar, Krsek Pavel, Zamecnik Josef, Meijer Lisethe, Scicluna Brendon P., Schouten-van Meeteren Antoinette Y. N., Mühlebner Angelika, Mills James D., Aronica Eleonora The coding and non-coding transcriptional landscape of subependymal giant cell astrocytomas Brain 2019;143 (1):131-149 [PubMed]

2018

• van Scheppingen Jackelien Astrocytes as mediators of inflammation in epilepsy: focus on tuberous sclerosis complex 2018. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Aronica E. M. A.; Co-supervisor: van Vliet E. A.)
• Drion C. M., van Scheppingen J., Arena A., Geijtenbeek K. W., Kooijman L., van Vliet E. A., Aronica E., Gorter J. A. Effects of rapamycin and curcumin on inflammation and oxidative stress in vitro and in vivo - in search of potential anti-epileptogenic strategies for temporal lobe epilepsy Journal of neuroinflammation 2018;15 (1) [PubMed]
• Korotkov Anatoly, Broekaart Diede W. M., van Scheppingen Jackelien, Anink Jasper J., Baayen Johannes C., Idema Sander, Gorter Jan A., Aronica Eleonora, van Vliet Erwin A. Increased expression of matrix metalloproteinase 3 can be attenuated by inhibition of microRNA-155 in cultured human astrocytes Journal of neuroinflammation 2018;15 (1) [PubMed]
• van Scheppingen Jackelien, Mills James D., Zimmer Till S., Broekaart Diede W. M., Iori Valentina, Bongaarts Anika, Anink Jasper J., Iyer Anand M., Korotkov Anatoly, Jansen Floor E., van Hecke Wim, Spliet Wim G., van Rijen Peter C., Baayen Johannes C., Vezzani Annamaria, van Vliet Erwin A., Aronica Eleonora miR147b: A novel key regulator of interleukin 1 beta-mediated inflammation in human astrocytes Glia 2018;66 (5):1082-1097 [PubMed]
• Curatolo Paolo, Moavero Romina, van Scheppingen Jackelien, Aronica Eleonora mTOR dysregulation and tuberous sclerosis-related epilepsy Expert review of neurotherapeutics 2018;18 (3):185-201 [PubMed]

2017

• Mills James D., Iyer Anand M., van Scheppingen Jackelien, Bongaarts Anika, Anink Jasper J., Janssen Bart, Zimmer Till S., Spliet Wim G., van Rijen Peter C., Jansen Floor E., Feucht Martha, Hainfellner Johannes A., Krsek Pavel, Zamecnik Josef, Kotulska Katarzyna, Jozwiak Sergiusz, Jansen Anna, Lagae Lieven, Curatolo Paolo, Kwiatkowski David J., Pasterkamp R. Jeroen, Senthilkumar Ketharini, von Oerthel Lars, Hoekman Marco F., Gorter Jan A., Crino Peter B., Mühlebner Angelika, Scicluna Brendon P., Aronica Eleonora Coding and small non-coding transcriptional landscape of tuberous sclerosis complex cortical tubers: implications for pathophysiology and treatment Scientific reports 2017;7 (1):8089 [PubMed]
• Hendrickx Debbie A. E., van Scheppingen Jackelien, van der Poel Marlijn, Bossers Koen, Schuurman Karianne G., van Eden Corbert G., Hol Elly M., Hamann Jörg, Huitinga Inge Gene Expression Profiling of Multiple Sclerosis Pathology Identifies Early Patterns of Demyelination Surrounding Chronic Active Lesions Frontiers in immunology 2017;8:1810 [PubMed]
• Broekaart Diede W. M., van Scheppingen Jackelien, Geijtenbeek Karlijne W., Zuidberg Mark R. J., Anink Jasper J., Baayen Johannes C., Mühlebner Angelika, Aronica Eleonora, Gorter Jan A., van Vliet Erwin A. Increased expression of (immuno) proteasome subunits during epileptogenesis is attenuated by inhibition of the mammalian target of rapamycin pathway Epilepsia 2017;58 (8):1462-1472 [PubMed]

2016

• van Scheppingen J., Broekaart D. W. M., Scholl T., Zuidberg M. R. J., Anink J. J., Spliet W. G., van Rijen P. C., Czech T., Hainfellner J. A., Feucht M., Mühlebner A., van Vliet E. A., Aronica E. Dysregulation of the (immuno)proteasome pathway in malformations of cortical development Journal of neuroinflammation 2016;13 (1):202 [PubMed]
• van Scheppingen J., Iyer A. M., Prabowo A. S., Mühlebner A., Anink J. J., Scholl T., Feucht M., Jansen F. E., Spliet W. G., Krsek P., Zamecnik J., Buccoliero A. M., Giordano F., Genitori L., Kotulska K., Jozwiak S., Jaworski J., Liszewska E., van Vliet E. A., Aronica E. Expression of microRNAs miR21, miR146a, and miR155 in tuberous sclerosis complex cortical tubers and their regulation in human astrocytes and SEGA-derived cell cultures Glia 2016;64 (6):1066-1082 [PubMed]
• Ruffolo Gabriele, Iyer Anand, Cifelli Pierangelo, Roseti Cristina, Mühlebner Angelika, van Scheppingen Jackelien, Scholl Theresa, Hainfellner Johannes A., Feucht Martha, Krsek Pavel, Zamecnik Josef, Jansen Floor E., Spliet Wim G. M., Limatola Cristina, Aronica Eleonora, Palma Eleonora Functional aspects of early brain development are preserved in tuberous sclerosis complex (TSC) epileptogenic lesions Neurobiology of disease 2016;95:93-101 [PubMed]
• Mühlebner Angelika, van Scheppingen Jackelien, Hulshof Hanna M., Scholl Theresa, Iyer Anand M., Anink Jasper J., van den Ouweland Ans M. W., Nellist Mark D., Jansen Floor E., Spliet Wim G. M., Krsek Pavel, Benova Barbora, Zamecnik Josef, Crino Peter B., Prayer Daniela, Czech Thomas, Wöhrer Adelheid, Rahimi Jasmin, Höftberger Romana, Hainfellner Johannes A., Feucht Martha, Aronica Eleonora Novel Histopathological Patterns in Cortical Tubers of Epilepsy Surgery Patients with Tuberous Sclerosis Complex PLoS ONE 2016;11 (6):e0157396 [PubMed]
• Fuso A., Iyer A. M., van Scheppingen J., Maccarrone M., Scholl T., Hainfellner J. A., Feucht M., Jansen F. E., Spliet W. G., Krsek P., Zamecnik J., Mühlebner A., Aronica E. Promoter-Specific Hypomethylation Correlates with IL-1β Overexpression in Tuberous Sclerosis Complex (TSC) Journal of molecular neuroscience 2016;59 (4):464-470 [PubMed]
• Mühlebner Angelika, Iyer Anand M., van Scheppingen Jackelien, Anink Jasper J., Jansen Floor E., Veersema Tim J., Braun Kees P., Spliet Wim G. M., van Hecke Wim, Söylemezoğlu Figen, Feucht Martha, Krsek Pavel, Zamecnik Josef, Bien Christian G., Polster Tilman, Coras Roland, Blümcke Ingmar, Aronica Eleonora Specific pattern of maturation and differentiation in the formation of cortical tubers in tuberous sclerosis omplex (TSC): evidence from layer-specific marker expression Journal of neurodevelopmental disorders 2016;8:9 [PubMed]

2015

• Prabowo A. S., van Scheppingen J., Iyer A. M., Anink J. J., Spliet W. G. M., van Rijen P. C., Schouten-van Meeteren A. Y. N., Aronica E. Differential expression and clinical significance of three inflammation-related microRNAs in gangliogliomas Journal of neuroinflammation 2015;12 (1):97 [PubMed]

2014

• Kovacs G. G., Adle-Biassette H., Milenkovic I., Cipriani S., van Scheppingen J., Aronica E. Linking pathways in the developing and aging brain with neurodegeneration Neuroscience 2014;269:152-172 [PubMed]
• Iyer A. M., van Scheppingen J., Milenkovic I., Anink J. J., Lim D., Genazzani A. A., Adle-Biassette H., Kovacs G. G., Aronica E. Metabotropic glutamate receptor 5 in Down's syndrome hippocampus during development: increased expression in astrocytes Current Alzheimer research 2014;11 (7):694-705 [PubMed]
• Iyer Anand M., van Scheppingen Jackelien, Milenkovic Ivan, Anink Jasper J., Adle-Biassette Homa, Kovacs Gabor G., Aronica Eleonora mTOR Hyperactivation in down syndrome hippocampus appears early during development Journal of neuropathology and experimental neurology 2014;73 (7):671-683 [PubMed]

2013

• Iyer Anand, van Scheppingen Jackelien, Anink Jasper, Milenkovic Ivan, Kovács Gabor G., Aronica Eleonora Developmental patterns of DR6 in normal human hippocampus and in Down syndrome Journal of neurodevelopmental disorders 2013;5 (1):10 [PubMed]