L.C. Liebrand MSc publications

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Publications MSc L.C. Liebrand

Positions
PhD Candidate, Research Associate
Main activities
Research
Specialisation
(Diffusion-weighted) Magnetic Resonance Imaging (MRI)
Focus of research

Currently, I am working on neuroimaging for (ischemic) stroke at the Department of Biomedical Engineering and Physics. As a collaborator on the STAIRS (Stroke treatment decision support by Artificial Intelligence for analysis of MR images) project, my aim is to accelerate magnetic resonance imaging (MRI) and to simultaneously enable detection of stroke in the acute setting with aid of deep learning. In our group, we will develop an efficient way to combine different MRI modalities (e.g., diffusion-weighted MRI (dMRI), and fluid-attenuated inversion recovery (FLAIR)) into a useful tool for clinical decision making.

Previously, I investigated deep brain stimulation (DBS) for obsessive-compulsive disorder (OCD) and treatment-resistant depression (TRD) at the Department of Psychiatry. My focus was on finding the optimal target structures in white matter with dMRI (treatment optimization) and imaging-based prediction of individual treatment outcome (improved patient selection). In collaboration with the neurosurgeons, we updated the DBS targeting strategies for psychiatric DBS to include information on individual white matter structures.

My other interests include high-resolution and high-field (7T) dMRI and their application in research or in the clinic.

2020

  • Liebrand Luka C., Natarajan Samuel J., Caan Matthan W. A., Schuurman P. Richard, van den Munckhof Pepijn, de Kwaasteniet Bart, Luigjes Judy, Bergfeld Isidoor O., Denys Damiaan, van Wingen Guido A. Distance to white matter trajectories is associated with treatment response to internal capsule deep brain stimulation in treatment-refractory depression NeuroImage. Clinical 2020;28 [PubMed]
  • van Westen Maarten, Rietveld Erik, Bergfeld Isidoor O., de Koning Pelle, Vullink Nienke, Ooms Pieter, Graat Ilse, Liebrand Luka, van den Munckhof Pepijn, Schuurman Rick, Denys Damiaan Optimizing Deep Brain Stimulation Parameters in Obsessive–Compulsive Disorder Neuromodulation 2020 [PubMed]
  • Liebrand Luka C., van Wingen Guido A., Vos Frans M., Denys Damiaan, Caan Matthan W. A. Spatial versus angular resolution for tractography-assisted planning of deep brain stimulation NeuroImage. Clinical 2020;25 [PubMed]

2019

  • Liebrand L. C., Caan M. W. A., Schuurman P. R., van den Munckhof P., Figee M., Denys D., van Wingen G. A. Individual white matter bundle trajectories are associated with deep brain stimulation response in obsessive-compulsive disorder Brain stimulation 2019;12 (2):353-360 [PubMed]

2017

  • Vos Bart E., Liebrand Luka C., Vahabi Mahsa, Biebricher Andreas, Wuite Gijs J. L., Peterman Erwin J. G., Kurniawan Nicholas A., MacKintosh Fred C., Koenderink Gijsje H. Programming the mechanics of cohesive fiber networks by compression Soft matter 2017;13 (47):8886-8893 [PubMed]