Publications MSc L.H. Bukkems
- Positions
- PhD Candidate, Other Academic Staff
- Main activities
- Research
- Specialisation
- Population Pharmacokinetics and Pharmacodynamics
- Focus of research
PKPD of the novel extended half-life (EHL) coagulation factors used for the prophylactic treatment of hemophilia
Amsterdam UMC Research Institutes
AMC departments
All publications
2021
- Bukkems Laura H., Preijers Tim, van Spengler Max W. F., Leebeek Frank W. G., Cnossen Marjon H., Mathôt Ron A. A. Comparison of the Pharmacokinetic Properties of Extended Half-Life and Recombinant Factor VIII Concentrates by in Silico Simulations Thrombosis and haemostasis 2021 [PubMed]
2020
- Bukkems Laura H., Heijdra Jessica M., Mathias Mary, Collins Peter W., Hay Charles R. M., Tait Robert C., Mangles Sarah, Myers Bethan, Evans G., Bailiff Benjamin, Curry Nicola, Payne Jeanette, Austin Steve, Goedhart Tine M. H. J., Leebeek Frank W. G., Meijer Karina, Fijnvandraat Karin, Chowdary Pratima, Mathôt Ron A. A., Cnossen Marjon H. A Novel, Enriched Population Pharmacokinetic Model for Recombinant Factor VIII-Fc Fusion Protein Concentrate in Hemophilia A Patients Thrombosis and haemostasis 2020;120 (5):747-757 [PubMed]
- de Jager Nico C. B., Bukkems Laura H., Heijdra Jessica M., Hazendonk Carolien H. C. A. M., Fijnvandraat Karin, Meijer Karina, Eikenboom Jeroen, Laros - van Gorkom Britta A. P., Leebeek Frank W. G., Cnossen Marjon H., Mathôt Ron A. A., Collins P. W., Kruip M. J. H. A., Polinder S., Lock J., van Moort I., Goedhart M. C. H. J., Coppens M., Peters M., Preijers T., Brons P., van der Meer F. J. M., Schutgens R. E. G., Fischer K., Driessens M. H. E., Zwaan C. M., van Vliet I., Liesner R., Chowdary P., Keeling D. One piece of the puzzle: Population pharmacokinetics of FVIII during perioperative Haemate P®/Humate P® treatment in von Willebrand disease patients Journal of thrombosis and haemostasis 2020;18 (2):295-305 [PubMed]
- Valke Lars L. F. G., Bukkems Laura H., Barteling Wideke, Laros-van Gorkom Britta A. P., Blijlevens Nicole M. A., Mathôt Ron A. A., van Heerde Waander L., Schols Saskia E. M. Pharmacodynamic monitoring of factor VIII replacement therapy in hemophilia A: Combining thrombin and plasmin generation Journal of thrombosis and haemostasis 2020;18 (12):3222-3231 [PubMed]
- van Moort Iris, Bukkems Laura H., Heijdra Jessica M., Schutgens Roger E. G., Laros-van Gorkom Britta A. P., Nieuwenhuizen Laurens, van der Meer Felix J. M., Fijnvandraat Karin, Ypma Paula, de Maat Moniek P. M., Leebeek Frank W. G., Meijer Karina, Eikenboom Jeroen, Mathôt Ron A. A., Cnossen Marjon H. Von Willebrand Factor and Factor VIII Clearance in Perioperative Hemophilia A Patients Thrombosis and haemostasis 2020;120 (7):1056-1065 [PubMed]
2018
- Bukkems Laura H., Roger Claire, Hodiamont Caspar J., Lefrant Jean-Yves, Juffermans Nicole P., Roberts Jason A., van Hest Reinier M. Predictive performance of a gentamicin population pharmacokinetic model in two western populations of critically ill patients International journal of antimicrobial agents 2018;52 (2):218-225 [PubMed]