M. Lowenberg MD PhD publications

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Publications MD PhD M. Lowenberg

Position
Medical Specialist
Main activities
Patient care, Research
Specialisation
Gastroenterology and hepatology
Focus of research

Inflammatory bowel diseases; T lymphocytes; mucosal immunity; signal transduction;  small molecules; glucocorticoids

2021

  • Stellingwerf M. E., Bemelman W. A., Löwenberg M., Ponsioen C. Y., D'Haens G. R., van Dieren S., Buskens C. J. A nationwide database study on colectomy and colorectal cancer in ulcerative colitis: what is the role of appendectomy? Colorectal disease 2021;23 (1):64-73 [PubMed]
  • Marquès Camí Miquel, Serracarbasa Alba, D'Haens Geert, Löwenberg Mark Characterization of Mucosal Lesions in Crohn's Disease Scored With Capsule Endoscopy: A Systematic Review Frontiers in Medicine 2021;7 [PubMed]
  • Strik Anne S., Löwenberg Mark, Mould Diane R., Berends Sophie E., Ponsioen Cyriel I., van den Brande Jan M. H., Jansen Jeroen M., Hoekman Daniël R., Brandse Johannan F., Duijvestein Marjolijn, Gecse Krisztina B., de Vries Annick, Mathôt Ron A., D’Haens Geert R. Efficacy of dashboard driven dosing of infliximab in inflammatory bowel disease patients; a randomized controlled trial Scandinavian journal of gastroenterology 2021;56 (2):145-154 [PubMed]

2020

  • Löwenberg Mark Anti-TNF Agents in Elderly IBD Patients: Cause for Concern? Journal of Crohn s & colitis 2020;14 (7):881-882 [PubMed]
  • Berends Sophie. E. Anti-TNF therapy in inflammatory bowel disease: Towards personalized medicine 2020. 251p. ISBN 9789090325651. [UvA Dissertations Online] University of Amsterdam. (Supervisors: D'Haens Geert. R. A. M., Mathot Ronald. A A.; Co-supervisor: Lowenberg Mark)
  • Hoekman Daniël R., Löwenberg Mark, van den Brink Gijs R., Ponsioen Cyriel Y., Benninga Marc A., D'Haens Geert R. A prospective study comparing patient-reported outcomes in Crohn's disease European journal of gastroenterology & hepatology 2020;32 (1):38-44 [PubMed]
  • Asscher Vera E. R., Biemans Vince B. C., Pierik Marieke J., Dijkstra Gerard, Löwenberg Mark, van der Marel Sander, de Boer Nanne K. H., Bodelier Alexander G. L., Jansen Jeroen M., West Rachel L., Haans Jeoffrey J. L., van Dop Willemijn A., Weersma Rinse K., Hoentjen Frank, Maljaars P. W. Jeroen Comorbidity, not patient age, is associated with impaired safety outcomes in vedolizumab- and ustekinumab-treated patients with inflammatory bowel disease—a prospective multicentre cohort study Alimentary pharmacology & therapeutics 2020;52 (8):1366-1376 [PubMed]
  • Wasmann Karin A, Study group members AMC , Buskens Christianne J., Bemelman Willem A., Hompes Roel, Tanis Pieter J., D'Haens Geert, Dolmaci Onur B., Groen Jip, van der Bilt Jarmila , Ponsioen Cyriel, Duijvestein Marjolijn, Lowenberg Mark, Wildenberg Manon E., Gecse Krisztina B. Complications While Waiting for IBD Surgery-Short Report Journal of Crohn s & colitis 2020;14 (2):277-280 [PubMed]
  • van Rijn Kyra L., Lansdorp Corine A., Tielbeek Jeroen A. W., Nio C. Yung, Buskens Christianne J., D'Haens Geert R. A. M., Löwenberg Mark, Stoker Jaap Evaluation of the modified Van Assche index for assessing response to anti-TNF therapy with MRI in perianal fistulizing Crohn's disease Clinical imaging 2020;59 (2):179-187 [PubMed]
  • Lansdorp Corine A., Gecse Krisztina B., Buskens Christianne J., Löwenberg Mark, Stoker Jaap, Bemelman Willem A., D’Haens Geert R.A.M., van Hulst Rob A. Hyperbaric oxygen therapy for the treatment of perianal fistulas in 20 patients with Crohn’s disease Alimentary pharmacology & therapeutics 2020 [PubMed]
  • van Aalst Mariëlle, Garcia Garrido Hannah M., van der Leun Josephine, Meek Bob, van Leeuwen Ester M. M., Löwenberg Mark, D'Haens Geert R., Ponsioen Cyriel Y. I., Grobusch Martin P., Goorhuis Abraham Immunogenicity of the Currently Recommended Pneumococcal Vaccination Schedule in Patients With Inflammatory Bowel Disease Clinical infectious diseases 2020;70 (4):595-604 [PubMed]
  • van Gennep Sara, de Boer Nanne K. H., Gielen Marieke E., Rietdijk Svend T., Gecse Krisztina B., Ponsioen Cyriel Y., Duijvestein Marjolijn, D’Haens Geert R., Löwenberg Mark, de Boer Angela G. E. M. Impaired Quality of Working Life in Inflammatory Bowel Disease Patients Digestive diseases and sciences 2020 [PubMed]
  • Berends Sophie E., Bloem Karien, de Vries Annick, Schaap Tiny, Rispens Theo, Strik Anne S., Talwar Rawina, Löwenberg Mark, DʼHaens Geert R., Mathôt Ron A. Monitoring of Adalimumab Concentrations at Home in Patients with Inflammatory Bowel Disease Using Dried Blood Samples Therapeutic drug monitoring 2020;42 (2):289-294 [PubMed]
  • Lie Mitchell R. K. L., Kreijne Joany E., Dijkstra Gerard, Löwenberg Mark, van Assche Gert, West Rachel L., van Noord Desiree, van der Meulen - de Jong Andrea E., Oldenburg Bas, Zaal Rianne J., Hansen Bettina E., de Vries Annemarie C., Janneke van der Woude Christien No Superiority of Tacrolimus Suppositories vs Beclomethasone Suppositories in a Randomized Trial of Patients With Refractory Ulcerative Proctitis Clinical gastroenterology and hepatology 2020;18 (8):1777-1784.e2 [PubMed]
  • Ma Christopher, Gecse Krisztina B., Duijvestein Marjolijn, Sandborn William J., Zou Guangyong, Shackelton Lisa M., Stitt Larry W., Parker Claire E., Bossuyt Peter, Löwenberg Mark, Khanna Reena, Vermeire Severine, Rutgeerts Paul, Feagan Brian G., Jairath Vipul, D'Haens Geert R. Reliability of Endoscopic Evaluation of Postoperative Recurrent Crohn's Disease Clinical gastroenterology and hepatology 2020;18 (9):2139-2141.e2 [PubMed]
  • Biemans Vince B. C., Sleutjes Jasmijn A. M., de Vries Annemarie C., Bodelier Alexander G. L., Dijkstra Gerard, Oldenburg Bas, Löwenberg Mark, van Bodegraven Adriaan A., van der Meulen-de Jong Andrea E., de Boer Nanne K. H., Srivastava Nidhi, West Rachel L., Römkens Tessa E. H., Horjus Talabur Horje Carmen S., Jansen Jeroen M., van der Woude C. Janneke, Hoekstra Jildou, Weersma Rinse K., van Schaik Fiona D. M., Hoentjen Frank, Pierik Marieke J., Fidder H. H., Ponsioen C. Y., Duijvestein M., Romberg-Camps M. J. L., Maljaars P. W. J., Bouma G., van der Marel S., de Jong D. J., Haans J. J. L. Tofacitinib for ulcerative colitis: results of the prospective Dutch Initiative on Crohn and Colitis (ICC) registry Alimentary pharmacology & therapeutics 2020;51 (9):880-888 [PubMed]
  • Biemans Vince B. C., van der Meulen-de Jong Andrea E., van der Woude Christine J., Löwenberg Mark, Dijkstra Gerard, Oldenburg Bas, de Boer Nanne K. H., van der Marel Sander, Bodelier Alexander G. L., Jansen Jeroen M., Haans Jeoffrey J. L., Theeuwen Rosaline, de Jong Dirk, Pierik Marie J., Hoentjen Frank Ustekinumab for Crohn's Disease: Results of the ICC Registry, a Nationwide Prospective Observational Cohort Study Journal of Crohn s & colitis 2020;14 (1):33-45 [PubMed]
  • Biemans Vince B. C., van der Woude C. Janneke, Dijkstra Gerard, van der Meulen-de Jong Andrea E., Löwenberg Mark, de Boer Nanne K., Oldenburg Bas, Srivastava Nidhi, Jansen Jeroen M., Bodelier Alexander G. L., West Rachel L., de Vries Annemarie C., Haans Jeoffrey J. L., de Jong Dirk, Hoentjen Frank, Pierik Marieke J. Ustekinumab is associated with superior effectiveness outcomes compared to vedolizumab in Crohn’s disease patients with prior failure to anti-TNF treatment Alimentary pharmacology & therapeutics 2020;52 (1):123-134 [PubMed]
  • Rouvroye Maxine D., Tack Greetje J., Mom Constantijne H., Lissenberg-Witte Birgit I., Pierik Marieke J., Neefjes-Borst E. Andra, de Boer Nanne K. H., Löwenberg M., Bodelier A., Verbeek W. H., Schoon E., Witteman E. M., Herwaarden M. A., van der Woude C. J., Lutgens M., Kouw E., van der Veek P. J., van der Hulst R. W., Sipkema H., Nissen L. H. C., Bus P. J., van der Meulen A. E., de Bruijne F. H., van der Waaij L. A., Noomen C. G., Jharap B., Schmittgens S., Jansen J. M., Hoentjen F., Lammertink M. H. A., Houben G. M. P., Minderhoud I. M., Dijkstra G., Oldenburg B., Sikkens M. S. G., van Tuyl S. A., van Bodegraven A. A. Vulvar and vaginal neoplasia in women with inflammatory bowel disease Digestive and liver disease 2020;52 (2):149–155 [PubMed]

2019

  • Berends Sophie E., Strik Anne S., Löwenberg Mark, D’Haens Geert R., Mathôt Ron A. A. Clinical Pharmacokinetic and Pharmacodynamic Considerations in the Treatment of Ulcerative Colitis Clinical pharmacokinetics 2019;58 (1):15-37 [PubMed]
  • Strik Anne S., D’Haens Geert R., Löwenberg Mark Hemolytic anemia after switching from infliximab originator to biosimilar CT-P13 in a patient with inflammatory bowel disease: A case report Clinical case reports 2019 [PubMed]
  • Strik Anne S., Löwenberg Mark, Buskens Christianne J., B. Gecse Krisztina, I. Ponsioen Cyriel, Bemelman Willem A., D’Haens Geert R. Higher anti-TNF serum levels are associated with perianal fistula closure in Crohn’s disease patients Scandinavian journal of gastroenterology 2019 [PubMed]
  • Berends Sophie E., Strik Anne S., Jansen Jeroen M., de Boer Nanne K., van Egmond Pleun S., Brandse Johannan F., Mathôt Ron A., D’Haens Geert R., Löwenberg Mark Pharmacokinetics of golimumab in moderate to severe ulcerative colitis: the GO-KINETIC study Scandinavian journal of gastroenterology 2019;54 (6):700-706 [PubMed]
  • Bots Steven J., Kuin Sabine, Ponsioen Cyriel Y., Gecse Krisztina B., Duijvestein Marjolijn, D’Haens Geert R., Löwenberg Mark Relapse rates and predictors for relapse in a real-life cohort of IBD patients after discontinuation of anti-TNF therapy Scandinavian journal of gastroenterology 2019;54 (3):281-288 [PubMed]
  • Löwenberg Mark, van der Vlugt Manon Risk of Progression of Low-Grade Dysplasia to Advanced Neoplasia in Inflammatory Bowel Disease Journal of Crohn s & colitis 2019;13 (12):1483-1484 [PubMed]
  • van Gennep Sara, Konté Kadère, Meijer Berrie, Heymans Martijn W., D’Haens Geert R., Löwenberg Mark, de Boer Nanne K. H. Systematic review with meta-analysis: risk factors for thiopurine-induced leukopenia in IBD Alimentary pharmacology & therapeutics 2019;50 (5):484-506 [PubMed]
  • Strik Anne S., Berends Sophie E., Löwenberg Mark Therapeutic drug monitoring-based dosing of TNF inhibitors in inflammatory bowel disease: the way forward? Expert review of clinical pharmacology 2019;12 (9):885-891 [PubMed]
  • de Jong Djuna C., Löwenberg Mark, Koumoutsos Ioannis, Ray Shuvra, Mawdsley Joel, Anderson Simon, Sanderson Jeremy D., Gecse Krisztina, Ponsioen Cyriel Y., D'Haens Geert R., Irving Peter M., Samaan Mark A. Validation and Investigation of the Operating Characteristics of the Ulcerative Colitis Endoscopic Index of Severity Inflammatory bowel diseases 2019;25 (5):937-944 [PubMed]
  • Biemans Vince B. C., van der Woude C. Janneke, Dijkstra Gerard, van der Meulen-de Jong Andrea E., Oldenburg Bas, de Boer Nanne K., Löwenberg Mark, Srivastava Nidhi, Bodelier Alexander G. L., West Rachel L., Jansen Jeroen M., de Vries Annemarie C., Haans Jeoffrey J. L., de Jong Dirk J., Pierik Marie J., Hoentjen Frank Vedolizumab for Inflammatory Bowel Disease: Two-Year Results of the Initiative on Crohn and Colitis (ICC) Registry, A Nationwide Prospective Observational Cohort Study: ICC Registry – Vedolizumab Clinical pharmacology and therapeutics 2019 [PubMed]
  • Löwenberg Mark, Vermeire Severine, Mostafavi Nahid, Hoentjen Frank, Franchimont Denis, Bossuyt Peter, Hindryckx Pieter, Rispens Theo, de Vries Annick, van der Woude C. Janneke, Berends Sophie, Ambarus Carmen A., Mathot Ron, Clasquin Esme, Baert Filip, D'Haens Geert Vedolizumab Induces Endoscopic and Histologic Remission in Patients With Crohn's Disease Gastroenterology 2019;157 (4):997-1006.e6 [PubMed]

2018

  • Berends Sophie E., Strik Anne S., van Selm Juliet C., Löwenberg Mark, Ponsioen Cyriel Y., D'Haens Geert R., Mathôt Ron A. Explaining Interpatient Variability in Adalimumab Pharmacokinetics in Patients with Crohn's Disease Therapeutic drug monitoring 2018;40 (2):202-211 [PubMed]
  • Visschedijk Marijn C., Spekhorst Lieke M., Cheng Shih-Chin, van Loo Ellen S., Jansen B. H. Dianne, Blokzijl Tjasso, Kil Hyunsuk, de Jong Dirk J., Pierik Marieke, Maljaars Jeroen P. W. J., van der Woude C. Janneke, van Bodegraven Adriaan A., Oldenburg Bas, Löwenberg Mark, Nieuwenhuijs Vincent B., Imhann Floris, van Sommeren Suzanne, Alberts Rudi, Xavier Ramnik J., Dijkstra Gerard, Faber Klaas Nico, Aldaz C. Marcelo, Weersma Rinse K., Festen Eleonora A. M. Genomic and expression analyses identify a disease modifying variant for fibrostenotic Crohn's disease Journal of Crohn s & colitis 2018;12 (5):582-588 [PubMed]
  • Momozawa Yukihide, Dmitrieva Julia, Théâtre Emilie, Deffontaine Valérie, Rahmouni Souad, Charloteaux Benoît, Crins François, Docampo Elisa, Elansary Mahmoud, Gori Ann-Stephan, Lecut Christelle, Mariman Rob, Mni Myriam, Oury C. cile, Altukhov Ilya, Alexeev Dmitry, Aulchenko Yuri, Amininejad Leila, Bouma Gerd, Hoentjen Frank, Löwenberg Mark, Oldenburg Bas, Pierik Marieke J., Vander Meulen-de Jong Andrea E., van der Woude C. Janneke, Visschedijk Marijn C., Lathrop Mark, Hugot Jean-Pierre, Weersma Rinse K., de Vos Martine, Franchimont Denis, Vermeire Severine, Kubo Michiaki, Louis Edouard, Georges Michel, Abraham Clara, Achkar Jean-Paul, Ahmad Tariq, Ananthakrishnan Ashwin N., Andersen Vibeke, Anderson Carl A., Andrews Jane M., Annese Vito, Aumais Guy, Baidoo Leonard, Baldassano Robert N., Bampton Peter A., Barclay Murray, Ponsioen Cyriel Y., van Limbergen Johan E. IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes Nature communications 2018;9 (1) [PubMed]
  • Duijvis Nicolette W. IBD therapy redesigned: From established therapeutic regimens to prospective epigenetic approaches 2018. 192p. ISBN 9789402812756. [UvA Dissertations Online] University of Amsterdam. (Supervisors: de Jonge W. J., D'Haens G. R. A. M. , Löwenberg M.; Co-supervisor: te Velde A. A.)
  • de Bruyn Jessica R., Becker Marte A., Steenkamer Jessica, Wildenberg Manon E., Meijer Sybren L., Buskens Christianne J., Bemelman Willem A., Löwenberg Mark, Ponsioen Cyriel Y., van den Brink Gijs R., D'Haens Geert R. Intestinal fibrosis is associated with lack of response to Infliximab therapy in Crohn's disease PLoS ONE 2018;13 (1):e0190999 [PubMed]
  • Panés Julián, García-Olmo Damián, van Assche Gert, Colombel Jean Frederic, Reinisch Walter, Baumgart Daniel C., Dignass Axel, Nachury Maria, Ferrante Marc, Kazemi-Shirazi Lili, Grimaud Jean C., de la Portilla Fernando, Goldin Eran, Richard Marie Paule, Diez Mary Carmen, Tagarro Ignacio, Leselbaum Anne, Danese Silvio, Stift Anton, Tschmelitsch J. rg, Mrak Karl, Tilg Herbert, Kroberger Irmgard, D'Hoore André, de Looze Danny, Baert Filip, Pattyn Paul, Zerbib Philippe, Zerbib Frank, Viennot Stéphanie, Dupas Jean-Louis, Orsoni Pierre-Charles, Hebuterne Xavier, Rahili Amine, Allez Matthieu, Panis Yves, Reinshagen Max, Scherer Roland, Sturm Andreas, Kruis Wolfgang, Duek Daniel-Simon, Waterman Matti, Lahat-Zok Adi, Zmora Oded, Tulchinsky Hagit, Edden Yair, Spinelli Antonino, Annese Vito, Angriman Imerio, Riegler Gabriele, Selvaggi Francesco, Oldenburg Bas, Gilissen Lennard, van Montfort Gust, Lowenberg Mark, Bemelman Adrianus Willem, Almenara Raúl, Martín Arranz María Dolores, García-Arranz Mariano, Pérez Gisbert Javier, Palasí Rosana, Samsó Carlos Taxonera, Herrera Justiniano Jose Manuel, Rada Ricardo, Butrón M. Teresa, López Daniel Carpio, López-Sanromán Antonio, Hinojosa de Val Joaquín, Solana Amparo, González Argenté F. Xavier, Pastor Carlos, Guadalajara Hector Long-term Efficacy and Safety of Stem Cell Therapy (Cx601) for Complex Perianal Fistulas in Patients With Crohn's Disease Gastroenterology 2018;154 (5):1334-1342.e4 [PubMed]
  • Severs Mirjam, Spekhorst Lieke M., Mangen Marie-Josée J., Dijkstra Gerard, Löwenberg Mark, Hoentjen Frank, van der Meulen-de Jong Andrea E., Pierik Marieke, Ponsioen Cyriel Y., Bouma Gerd, van der Woude Janneke C., van der Valk Mirthe E., Romberg-Camps Marielle J. L., Clemens Cees H. M., van de Meeberg Paul, Mahmmod Nofel, Jansen Jeroen, Jharap Bindia, Weersma Rinse K., Oldenburg Bas, Festen Eleonora A. M., Fidder Herma H. Sex-Related Differences in Patients with Inflammatory Bowel Disease: Results of 2 Prospective Cohort Studies Inflammatory bowel diseases 2018;24 (6):1298-1306 [PubMed]
  • van Gennep Sara, de Boer Nanne K., D'Haens Geert R., Löwenberg Mark Thiopurine Treatment in Ulcerative Colitis: A Critical Review of the Evidence for Current Clinical Practice Inflammatory bowel diseases 2018;24 (1):67-77 [PubMed]
  • Bots S., Nylund K., Löwenberg M., Gecse K., Gilja O. H., D’Haens G. Ultrasound for assessing disease activity in IBD patients: A systematic review of activity scores Journal of Crohn s & colitis 2018;12 (8):920-929 [PubMed]

2017

  • Boxhoorn Lotte, Stoof Tom J., de Meij Tim, Hoentjen Frank, Oldenburg Bas, Bouma Gerd, Löwenberg Mark, van Bodegraven Adriaan A., de Boer Nanne K. H. Clinical experience and diagnostic algorithm of vulval Crohn's disease European journal of gastroenterology & hepatology 2017;29 (7):838-843 [PubMed]
  • Spekhorst Lieke M., Imhann Floris, Festen Eleonora A. M., van Bodegraven Ad A., de Boer Nanne K. H., Bouma Gerd, Fidder Herma H., D'Haens Geert, Hoentjen Frank, Hommes Daan W., de Jong Dirk J., Löwenberg Mark, Maljaars P. W. Jeroen, van der Meulen-de Jong Andrea E., Oldenburg Bas, Pierik Marieke J., Ponsioen Cyriel Y., Stokkers Pieter C., Verspaget Hein W., Visschedijk Marijn C., van der Woude C. Janneke, Dijkstra Gerard, Weersma Rinse K. Cohort profile: design and first results of the Dutch IBD Biobank: a prospective, nationwide biobank of patients with inflammatory bowel disease BMJ open 2017;7 (11):e016695 [PubMed]
  • van Gennep Sara, Sahami Saloomeh, Buskens Christianne J., van den Brink Gijs R., Ponsioen Cyriel Y., D'Hoore André, de Buck van Overstraeten Anthony, van Assche Gert, Ferrante Marc, Vermeire Séverine, Bemelman Willem A., D'Haens Geert R. A. M., Löwenberg Mark Comparison of health-related quality of life and disability in ulcerative colitis patients following restorative proctocolectomy with ileal pouch-anal anastomosis versus anti-tumor necrosis factor therapy European journal of gastroenterology & hepatology 2017;29 (3):338-344 [PubMed]
  • Strik Anne S., Berends Sophie E., Mathôt Ron A., D'Haens Geert R., Löwenberg Mark Golimumab for moderate to severe ulcerative colitis Expert review of gastroenterology & hepatology 2017;11 (5):401-406 [PubMed]
  • Bots S. J. A., Hoekman D. R., Benninga M. A., Ponsioen C. Y., D'Haens G. R., Löwenberg M. Patterns of anti-TNF use and associated treatment outcomes in inflammatory bowel disease patients: results from an analysis of Dutch health insurance claims data Netherlands journal of medicine 2017;75 (10):432-442 [PubMed]
  • Spekhorst Lieke M., Oldenburg Bas, van Bodegraven Ad A., de Jong Dirk J., Imhann Floris, van der Meulen-de Jong Andrea E., Pierik Marieke J., van der Woude Janneke C., Dijkstra Gerard, D'Haens Geert, Löwenberg Mark, Weersma Rinse K., Festen Eleonora A. M. Prevalence of- and risk factors for work disability in Dutch patients with inflammatory bowel disease World journal of gastroenterology 2017;23 (46):8182-8192 [PubMed]
  • Sahami S., Konté K., Buskens C. J., Tanis P. J., Löwenberg M., Ponsioen C. J., van den Brink G. R., Bemelman W. A., D'Haens G. R. Risk factors for proximal disease extension and colectomy in left-sided ulcerative colitis United European gastroenterology journal 2017;5 (4):554-562 [PubMed]
  • Strik A. S., van den Brink G. R., Ponsioen C., Mathot R., Löwenberg M., D'Haens G. R. Suppression of anti-drug antibodies to infliximab or adalimumab with the addition of an immunomodulator in patients with inflammatory bowel disease Alimentary pharmacology & therapeutics 2017;45 (8):1128-1134 [PubMed]
  • Spekhorst L. M., Severs M., de Boer N. K. H., Festen E. A. M., Fidder H. H., Hoentjen F., Imhann F., de Jong D. J., van der Meulen-de Jong A. E., Pierik M. J., van der Woude C. J., Dijkstra G., Ponsioen C. Y., Lowenberg M., Oldenburg B., Weersma R. K. The Impact of Ethnicity and Country of Birth on Inflammatory Bowel Disease Phenotype: a Prospective Cohort Study Journal of Crohn s & colitis 2017;11 (12):1463-1470 [PubMed]

2016

  • Gardenbroek Tjibbe J., Pinkney Thomas D., Sahami Saloomeh, Morton Dion G., Buskens Christianne J., Ponsioen Cyriel Y., Tanis Pieter J., Löwenberg Mark, van den Brink Gijs R., Broeders Ivo A. M. J., Pullens Hendrikus J. M., Seerden Tom, Boom Maarten J., Mallant-Hent Rosalie C., Pierik Robert E. G. J. M., Vecht Juda, Sosef Meindert N., van Nunen Annick B., van Wagensveld Bart A., Stokkers Pieter C. F., Gerhards Michael F., Jansen Jeroen M., Acherman Yair, Depla Annekatrien C. T. M., Mannaerts Guido H. H., West Rachel, Iqbal Tariq, Pathmakanthan Shrikanth, Howard Rebecca, Magill Laura, Singh Baljit, Oo Ye H., Negpodiev Dmitri, Dijkgraaf Marcel G. W., D'Haens Geert R. A. M., Bemelman Willem A. Erratum to: The ACCURE-trial: the effect of appendectomy on the clinical course of ulcerative colitis, a randomised international multicenter trial (NTR2883) and the ACCURE-UK trial: a randomised external pilot trial (ISRCTN56523019) BMC surgery 2016;16 (1):1 [PubMed]
  • Jansen Laura, Vos Xander G., Löwenberg Mark Herpes simplex induced necrotizing tonsillitis in an immunocompromised patient with ulcerative colitis World journal of clinical cases 2016;4 (2):60-62 [PubMed]
  • Samaan Mark A., de Jong Djuna, Sahami Saloomeh, Morgan Samantha, Fragkos Konstantinos, Subramaniam Sharmila, Kok Klaartje, Makanyanga Jesica, Barnova Ivana, Saravanapavan Hajeena, Parisi Ioanna, Di Caro Simona, Vega Roser, Rahman Farooq, McCartney Sara, Bloom Stuart L., van den Brink Gijs R., Löwenberg Mark, Ponsioen Cyriel Y., Buskens Christianne J., Tanis Pieter J., de Buck van Overstraeten Anthony, DʼHoore Andre, Bemelman Willem A., Dʼhaens Geert R. Incidence and Severity of Prepouch Ileitis: A Distinct Disease Entity or a Manifestation of Refractory Pouchitis? Inflammatory bowel diseases 2016;22 (3):662-668 [PubMed]
  • Vuitton L., Marteau P., Sandborn W. J., Levesque B. G., Feagan B., Vermeire S., Danese S., D'Haens G., Lowenberg M., Khanna R., Fiorino G., Travis S., Mary J. Y., Peyrin-Biroulet L. IOIBD technical review on endoscopic indices for Crohn's disease clinical trials Gut 2016;65 (9):1447-1455 [PubMed]
  • Strik A. S., Bots S. J. A., D'Haens G., Löwenberg M. Optimization of anti-TNF therapy in patients with Inflammatory Bowel Disease Expert review of clinical pharmacology 2016;9 (3):429-439 [PubMed]
  • Brandse Johannan F., Bennink Roel J., van Eeden Susanne, Löwenberg Mark, van den Brink Gijs R., Dʼhaens Geert R. Performance of Common Disease Activity Markers as a Reflection of Inflammatory Burden in Ulcerative Colitis Inflammatory bowel diseases 2016;22 (6):1384-1390 [PubMed]
  • Brandse Johannan F., Mathôt Ron A., van der Kleij Desiree, Rispens Theo, Ashruf Yaël, Jansen Jeroen M., Rietdijk Svend, Löwenberg Mark, Ponsioen Cyriel Y., Singh Sharat, van den Brink Gijs R., D'Haens Geert R. Pharmacokinetic Features and Presence of Antidrug Antibodies Associate With Response to Infliximab Induction Therapy in Patients With Moderate to Severe Ulcerative Colitis Clinical gastroenterology and hepatology 2016;14 (2):251-8.e1-2 [PubMed]
  • Visschedijk Marijn C., Alberts Rudi, Mucha Soren, Deelen Patrick, de Jong Dirk J., Pierik Marieke, Spekhorst Lieke M., Imhann Floris, van der Meulen-de Jong Andrea E., van der Woude C. Janneke, van Bodegraven Adriaan A., Oldenburg Bas, Löwenberg Mark, Dijkstra Gerard, Ellinghaus David, Schreiber Stefan, Wijmenga Cisca, Rivas Manuel A., Franke Andre, van Diemen Cleo C., Weersma Rinse K. Pooled Resequencing of 122 Ulcerative Colitis Genes in a Large Dutch Cohort Suggests Population-Specific Associations of Rare Variants in MUC2 PLoS ONE 2016;11 (8):e0159609 [PubMed]
  • Kuin Sabine, Stolte Suzan B., van den Brink Gijs R., Ponsioen Cyriel Y., Fockens Paul, D'Haens Geert R., Löwenberg Mark Short article: Remicade infusions at home: an alternative setting of infliximab therapy for patients with Crohn's disease European journal of gastroenterology & hepatology 2016;28 (2):222-225 [PubMed]
  • Duijvis Nicolette W., ten Hove Anne S., Ponsioen Cyriel I. J., van den Brink Gijs R., Buskens Christianne J., Bemelman Willem A., te Velde Anje A., D'Haens Geert R. A. M., Löwenberg Mark Similar Short- and Long-term Colectomy Rates with Ciclosporin and Infliximab Treatment in Hospitalised Ulcerative Colitis Patients Journal of Crohn s & colitis 2016;10 (7):821-827 [PubMed]
  • Hoekman Daniël R. Studies on inflammatory bowel disease and functional gastrointestinal disorders in children and adults 2016. 310p. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Benninga M. A., D'Haens G. R. A. M.; Co-supervisors: Löwenberg M., Vlieger A. M.)
  • Dujardin Romein W. G., Meijer Berrie, de Boer Nanne K. H., D'Haens Geert R., Löwenberg Mark Usefulness of mean corpuscular volume as a surrogate marker for monitoring thiopurine treatment in inflammatory bowel disease European journal of gastroenterology & hepatology 2016;28 (9):991-996 [PubMed]

2015

  • Kuiper Teaco, Alderlieste Yasser A., Tytgat Kristien M. A. J., Vlug Marije S., Nabuurs Joyce A., Bastiaansen Barbara A. J., Löwenberg Mark, Fockens Paul, Dekker Evelien Automatic optical diagnosis of small colorectal lesions by laser-induced autofluorescence Endoscopy 2015;47 (1):56-62 [PubMed]
  • Rossen Noortje G., Fuentes Susana, van der Spek Mirjam J., Tijssen Jan G., Hartman Jorn H. A., Duflou Ann, Löwenberg Mark, van den Brink Gijs R., Mathus-Vliegen Elisabeth M. H., de Vos Willem M., Zoetendal Erwin G., D'Haens Geert R., Ponsioen Cyriel Y. Findings From a Randomized Controlled Trial of Fecal Transplantation for Patients With Ulcerative Colitis Gastroenterology 2015;149 (1):110-118.e4 [PubMed]
  • Gecse Krisztina B., Brandse Johannan F., van Wilpe Sandra, Löwenberg Mark, Ponsioen Cyriel, van den Brink Gijs, D'Haens Geert Impact of disease location on fecal calprotectin levels in Crohn's disease Scandinavian journal of gastroenterology 2015;50 (7):841-847 [PubMed]
  • Brandse Johannan F., van den Brink Gijs R., Wildenberg Manon E., van der Kleij Desiree, Rispens Theo, Jansen Jeroen M., Mathôt Ron A., Ponsioen Cyriel Y., Löwenberg Mark, D'Haens Geert R. A. M. Loss of Infliximab Into Feces Is Associated With Lack of Response to Therapy in Patients With Severe Ulcerative Colitis Gastroenterology 2015;149 (2):350-5.e2 [PubMed]
  • Löwenberg Mark, D'Haens Geert Next-Generation Therapeutics for IBD Current gastroenterology reports 2015;17 (6):21 [PubMed]
  • D'Haens Geert, Löwenberg Mark, Samaan Mark A., Franchimont Denis, Ponsioen Cyriel, van den Brink Gijs R., Fockens Paul, Bossuyt Peter, Amininejad Leila, Rajamannar Gopalan, Lensink Elsemieke M., van Gossum Andre M. Safety and Feasibility of Using the Second-Generation Pillcam Colon Capsule to Assess Active Colonic Crohn's Disease Clinical gastroenterology and hepatology 2015;13 (8):1480-6.e3 [PubMed]
  • Brandse Johannan F., Vos Laura M. C., Jansen Jeroen, Schakel Toos, Ponsioen Cyriel I. J., van den Brink Gijs R., D'Haens Geert R., Löwenberg Mark Serum Concentration of Anti-TNF Antibodies, Adverse Effects and Quality of Life in Patients with Inflammatory Bowel Disease in Remission on Maintenance Treatment Journal of Crohn s & colitis 2015;9 (11):973-981 [PubMed]
  • Gardenbroek Tjibbe J., Pinkney Thomas D., Sahami Saloomeh, Morton Dion G., Buskens Christianne J., Ponsioen Cyriel Y., Tanis Pieter J., Löwenberg Mark, van den Brink Gijs R., Broeders Ivo A. M. J., Pullens Hendrikus J. M., Pullens Paul H. J. M., Seerden Tom, Boom Maarten J., Mallant-Hent Rosalie C., Pierik Robert E. G. J. M., Vecht Juda, Sosef Meindert N., van Nunen Annick B., van Wagensveld Bart A., Stokkers Pieter C. F., Gerhards Michael F., Jansen Jeroen M., Acherman Yair, Depla Annekatrien C. T. M., Mannaerts Guido H. H., West Rachel, Iqbal Tariq, Pathmakanthan Shrikanth, Howard Rebecca, Magill Laura, Singh Baljit, Oo Ye H., Htun Oo Ye, Negpodiev Dmitri, Dijkgraaf Marcel G. W., D'Haens Geert R. A. M., Bemelman Willem A. The ACCURE-trial: the effect of appendectomy on the clinical course of ulcerative colitis, a randomised international multicenter trial (NTR2883) and the ACCURE-UK trial: a randomised external pilot trial (ISRCTN56523019) BMC surgery 2015;15 (1):30 [PubMed]
  • Hoekman Daniël R., Brandse Johannan F., de Meij Tim G., Hummel Thalia Z., Löwenberg Mark, Benninga Marc A., D'Haens Geert R., Kindermann Angelika The association of infliximab trough levels with disease activity in pediatric inflammatory bowel disease Scandinavian journal of gastroenterology 2015;50 (9):1110-1117 [PubMed]

2014

  • Brandse Johannan F., Peters Charlotte P., Gecse Krisztina B., Eshuis Emma J., Jansen Jeroen M., Tuynman Hans A., Löwenberg Mark, Ponsioen Cyriel Y., van den Brink Gijs R., Dʼhaens Geert R. Effects of infliximab retreatment after consecutive discontinuation of infliximab and adalimumab in refractory Crohn's disease Inflammatory bowel diseases 2014;20 (2):251-258 [PubMed]
  • Jansen L. A. W., Knauff E. A. H., Tan S. S., Löwenberg M. Estimated hospital health costs of chronic abdominal pain in the Netherlands Netherlands journal of medicine 2014;72 (2):102-106 [PubMed]
  • Löwenberg Mark, de Boer Nanne K. H., Hoentjen Frank Golimumab for the treatment of ulcerative colitis Clinical and experimental gastroenterology 2014;7:53-59 [PubMed]
  • Meijs Simone, Gardenbroek Tjibbe J., Sprangers Mirjam A. G., Bemelman Willem A., Buskens Christianne J., D'Haens Geert R. A. M., Löwenberg Mark Health-related quality of life and disability in patients with ulcerative colitis and proctocolectomy with ileoanal pouch versus treatment with anti-TNF agents Journal of Crohn s & colitis 2014;8 (7):686-692 [PubMed]
  • Löwenberg Mark, Duijvis Nicolette W., Ponsioen Cyriel, van den Brink Gijs R., Fockens Paul, D'Haens Geert R. A. M. Length of hospital stay and associated hospital costs with infliximab versus cyclosporine in severe ulcerative colitis European journal of gastroenterology & hepatology 2014;26 (11):1240-1246 [PubMed]
  • de Boer Nanne K. H., Löwenberg Mark, Hoentjen Frank Management of Crohn's disease in poor responders to adalimumab Clinical and experimental gastroenterology 2014;7:83-92 [PubMed]
  • de Bruyn Jessica R., van Heeckeren Rosanne, Ponsioen Cyriel Y., van den Brink Gijs R., Löwenberg Mark, Bredenoord Albert J., Frijstein Gerard, D'Haens Geert R. Vitamin D deficiency in Crohn's disease and healthy controls: a prospective case-control study in the Netherlands Journal of Crohn s & colitis 2014;8 (10):1267-1273 [PubMed]

2013

  • Jansen Jos C., van Dop Willemijn A., Fockens Paul, Löwenberg Mark Acute pijn in de bovenbuik na veelvuldig braken: Het Boerhaave-syndroom Nederlands tijdschrift voor geneeskunde 2013;157 (35):A6374 [PubMed]
  • Löwenberg Mark, de Boer Nanne K. H., Dewint Pieter, Hoentjen Frank Behandeling van patiënten met ernstige glucocorticoïd-refractaire colitis ulcerosa: ciclosporine of infliximab? Nederlands tijdschrift voor geneeskunde 2013;157 (38):A6130 [PubMed]
  • Gecse Krisztina B., Khanna Reena, van den Brink Gijs R., Ponsioen Cyriel Y., Löwenberg Mark, Jairath Vipul, Travis Simon P. L., Sandborn William J., Feagan Brian G., D'Haens Geert R. A. M. Biosimilars in IBD: hope or expectation? Gut 2013;62 (6):803-807 [PubMed]
  • Löwenberg Mark, D'Haens Geert Novel targets for inflammatory bowel disease therapeutics Current gastroenterology reports 2013;15 (2):311 [PubMed]
  • Tielbeek Jeroen A. W., Löwenberg Mark, Bipat Shandra, Horsthuis Karin, Ponsioen Cyriel Y., D'Haens Geert R., Stoker Jaap Serial magnetic resonance imaging for monitoring medical therapy effects in Crohn's disease Inflammatory bowel diseases 2013;19 (9):1943-1950 [PubMed]
  • Verhaar Auke P., Wildenberg Manon E., Duijvestein Marjolijn, Vos Anne Christine W., Peppelenbosch Maikel P., Löwenberg Mark, Hommes Daniel W., van den Brink Gijs R. Superantigen-induced steroid resistance depends on activation of phospholipase cβ2 Journal of immunology (Baltimore, Md. 2013;190 (12):6589-6595 [PubMed]

2012

  • Löwenberg Mark, D'Haens Geert Mucosal Healing in Crohn's Disease: Relevance for Clinical Outcomes Current drug targets 2012;13 (10):1248-1251 [PubMed]

2011

  • Strehl Cindy, Gaber Timo, Löwenberg Mark, Hommes Daniel W., Verhaar Auke P., Schellmann Saskia, Hahne Martin, Fangradt Monique, Wagegg Markus, Hoff Paula, Scheffold Alexander, Spies Cornelia M., Burmester Gerd-Rüdiger, Buttgereit Frank Origin and functional activity of the membrane-bound glucocorticoid receptor Arthritis and rheumatism 2011;63 (12):3779-3788 [PubMed]

2009

  • de Jonge Wouter J., The Frans O., Löwenberg Mark, Boeckxstaens Guy E. P38 MAPK Inhibitor Semapimod Reduces Postoperative Ileus Via Peripheral and Central Mechanisms Gastroenterology 2009;136 (5):1841-1842 [PubMed]

2008

  • Löwenberg Mark, Stahn Cindy, Hommes Daniel W., Buttgereit Frank Novel insights into mechanisms of glucocorticoid action and the development of new glucocorticoid receptor ligands Steroids 2008;73 (9-10):1025-1029 [PubMed]

2007

  • Lowenberg Mark, Verhaar Auke P., van den Brink Gijs R., Hommes Daniel W. Glucocorticoid signaling: a nongenomic mechanism for T-cell immunosuppression Trends in molecular medicine 2007;13 (4):158-163 [PubMed]
  • Stahn Cindy, Löwenberg Mark, Hommes Daniel W., Buttgereit Frank Molecular mechanisms of glucocorticoid action and selective glucocorticoid receptor agonists Molecular and cellular endocrinology 2007;275 (1-2):71-78 [PubMed]
  • Lowenberg Mark Proximal signaling molecules as potential targets for anti-inflammatory therapy Current opinion in drug discovery & development 2007;10 (5):560-564 [PubMed]

2006

  • Löwenberg Mark, Scheffer Meike, Verhaar Auke, Peppelenbosch Maikel, Hommes Daniel A role for STAT5 in steroid-resistant UC? Inflammatory bowel diseases 2006;12 (7):665 [PubMed]
  • Löwenberg Mark, Peppelenbosch Maikel, Hommes Daniel Biological therapy in the management of recent-onset Crohn's disease: why, when and how? Drugs 2006;66 (11):1431-1439 [PubMed]
  • Löwenberg Mark, Verhaar Auke P., Bilderbeek Joyce, Marle Jan van, Buttgereit Frank, Peppelenbosch Maikel P., van Deventer Sander J., Hommes Daniel W. Glucocorticoids cause rapid dissociation of a T-cell-receptor-associated protein complex containing LCK and FYN EMBO reports 2006;7 (10):1023-1029 [PubMed]
  • Löwenberg Mark, Tuynman Jurriaan, Scheffer Meike, Verhaar Auke, Vermeulen Louis, van Deventer Sander, Hommes Daniel, Peppelenbosch Maikel Kinome analysis reveals nongenomic glucocorticoid receptor-dependent inhibition of insulin signaling Endocrinology 2006;147 (7):3555-3562 [PubMed]
  • Löwenberg M. Therapeutic agents and signal reduction in inflammatory bowel diseases 2006. 166p. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van Deventer S. J. H., Peppelenbosch M. P.; Co-supervisor: Hommes D. W.)

2005

  • Febbo Phillip G., Lowenberg Mark, Thorner Aaron R., Brown Myles, Loda Massimo, Golub Todd R. Androgen mediated regulation and functional implications of fkbp51 expression in prostate cancer Journal of urology 2005;173 (5):1772-1777 [PubMed]
  • Löwenberg Mark, Tuynman Jurriaan, Bilderbeek Joyce, Gaber Timo, Buttgereit Frank, van Deventer Sander, Peppelenbosch Maikel, Hommes Daniel Rapid immunosuppressive effects of glucocorticoids mediated through Lck and Fyn Blood 2005;106 (5):1703-1710 [PubMed]
  • Löwenberg Mark, Verhaar Auke, van den Blink Bernt, ten Kate Fibo, van Deventer Sander, Peppelenbosch Maikel, Hommes Daniel Specific inhibition of c-Raf activity by semapimod induces clinical remission in severe Crohn's disease Journal of immunology (Baltimore, Md. 2005;175 (4):2293-2300 [PubMed]

2004

  • Löwenberg M., Peppelenbosch M. P., Hommes D. W. Therapeutic modulation of signal transduction pathways Inflammatory bowel diseases 2004;10 (Suppl. 1):S52-S57 [PubMed]