A.L.M.A. ten Asbroek MEng PhD publications

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Publications MEng PhD A.L.M.A. ten Asbroek

Position
Assistant Professor
Main activities
Education, Research
Specialisation
molecular biology, stem cell biology
Focus of research

Modelling of complex genetic retinal disorders with the use of (induced) pluripotent stem cells

2021

  • Wagstaff Philip E., ten Asbroek Anneloor L. M. A., ten Brink Jacoline B., Jansonius Nomdo M., Bergen Arthur A. B. An alternative approach to produce versatile retinal organoids with accelerated ganglion cell development Scientific reports 2021;11 (1) [PubMed]

2020

  • Milićević Nemanja, Ten Brink Jacoline B, Ten Asbroek Anneloor L M A, Bergen Arthur A, Felder-Schmittbuhl Marie-Paule The circadian clock regulates RPE-mediated lactate transport via SLC16A1 (MCT1) Experimental eye research 2020;190:107861 [PubMed]

2019

  • Milićević Nemanja, Duursma Angelica, ten Asbroek Anneloor L. M. A., Felder-Schmittbuhl Marie-Paule, Bergen Arthur A. Does the circadian clock make RPE-mediated ion transport “tick” via SLC12A2 (NKCC1)? Chronobiology international 2019;36 (11):1592-1598 [PubMed]

2018

  • de Majo Martina, Topp Simon D., Smith Bradley N., Nishimura Agnes L., Chen Han-Jou, Gkazi Athina Soragia, Miller Jack, Wong Chun Hao, Vance Caroline, Baas Frank, ten Asbroek Anneloor L. M. A., Kenna Kevin P., Ticozzi Nicola, Redondo Alberto Garcia, Esteban-Pérez Jesús, Tiloca Cinzia, Verde Federico, Duga Stefano, Morrison Karen E., Shaw Pamela J., Kirby Janine, Turner Martin R., Talbot Kevin, Hardiman Orla, Glass Jonathan D., de Belleroche Jacqueline, Gellera Cinzia, Ratti Antonia, Al-Chalabi Ammar, Brown Robert H., Silani Vincenzo, Landers John E., Shaw Christopher E. ALS-associated missense and nonsense TBK1 mutations can both cause loss of kinase function Neurobiology of aging 2018;71:266.e1-266.e10 [PubMed]
  • Nicolas Aude, Kenna Kevin P., Renton Alan E., Ticozzi Nicola, Faghri Faraz, Chia Ruth, Dominov Janice A., Kenna Brendan J., Nalls Mike A., Keagle Pamela, Rivera Alberto M., van Rheenen Wouter, Murphy Natalie A., van Vugt Joke J. F. A., Geiger Joshua T., van der Spek Rick A., Pliner Hannah A., Smith Bradley N., Marangi Giuseppe, Topp Simon D., Abramzon Yevgeniya, Gkazi Athina Soragia, Eicher John D., Kenna Aoife, Logullo Francesco O., Simone Isabella L., Logroscino Giancarlo, Salvi Fabrizio, Bartolomei Ilaria, Borghero Giuseppe, Murru Maria Rita, Costantino Emanuela, Pani Carla, Puddu Roberta, Caredda Carla, Piras Valeria, Tranquilli Stefania, Cuccu Stefania, Corongiu Daniela, Melis Maurizio, Milia Antonio, Marrosu Francesco, Marrosu Maria Giovanna, Floris Gianluca, Cannas Antonino, Capasso Margherita, Baas Frank, ten Asbroek Anneloor L. M. A., Weber Markus Genome-wide Analyses Identify KIF5A as a Novel ALS Gene Neuron 2018;97 (6):1268-1283.e6 [PubMed]

2017

  • Smith Bradley N., Topp Simon D., Fallini Claudia, Shibata Hideki, Chen Han-Jou, Troakes Claire, King Andrew, Ticozzi Nicola, Kenna Kevin P., Soragia-Gkazi Athina, Miller Jack W., Sato Akane, Dias Diana Marques, Jeon Maryangel, Vance Caroline, Wong Chun Hao, de Majo Martina, Kattuah Wejdan, Mitchell Jacqueline C., Scotter Emma L., Parkin Nicholas W., Sapp Peter C., Nolan Matthew, Nestor Peter J., Simpson Michael, Weale Michael, Lek Monkel, Baas Frank, Vianney de Jong J. M., ten Asbroek Anneloor L. M. A., Redondo Alberto Garcia, Esteban-Pérez Jesús, Tiloca Cinzia, Verde Federico, Duga Stefano, Leigh Nigel, Pall Hardev, Morrison Karen E., Al-Chalabi Ammar, Shaw Pamela J., Kirby Janine, Turner Martin R., Talbot Kevin, Hardiman Orla, Glass Jonathan D., de Belleroche Jacqueline, Maki Masatoshi, Moss Stephen E., Miller Christopher, Gellera Cinzia, Ratti Antonia, Al-Sarraj Safa, Brown Robert H., Silani Vincenzo, Landers John E., Shaw Christopher E. Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis Science translational medicine 2017;9 (388):eaad9157 [PubMed]

2016

  • Kenna Kevin P., van Doormaal Perry T. C., Dekker Annelot M., Ticozzi Nicola, Kenna Brendan J., Diekstra Frank P., van Rheenen Wouter, van Eijk Kristel R., Jones Ashley R., Keagle Pamela, Shatunov Aleksey, Sproviero William, Smith Bradley N., van Es Michael A., Topp Simon D., Kenna Aoife, Miller Jack W., Fallini Claudia, Tiloca Cinzia, McLaughlin Russell L., Vance Caroline, Troakes Claire, Colombrita Claudia, Mora Gabriele, Calvo Andrea, Verde Federico, Al-Sarraj Safa, King Andrew, Calini Daniela, de Belleroche Jacqueline, Baas Frank, van der Kooi Anneke J., de Visser Marianne, ten Asbroek Anneloor L. M. A., Sapp Peter C., McKenna-Yasek Diane, Polak Meraida, Asress Seneshaw, Muñoz-Blanco José Luis, Strom Tim M., Meitinger Thomas, Morrison Karen E., Lauria Giuseppe, Williams Kelly L., Leigh P. Nigel, Nicholson Garth A., Blair Ian P., Leblond Claire S., Dion Patrick A., Rouleau Guy A. NEK1 variants confer susceptibility to amyotrophic lateral sclerosis Nature genetics 2016;48 (9):1037-1042 [PubMed]
  • Both Joeri, Wu Thijs, ten Asbroek Anneloor L. M. A., Baas Frank, Hulsebos Theo J. M. Oncogenic Properties of Candidate Oncogenes in Chromosome Region 17p11.2p12 in Human Osteosarcoma Cytogenetic and genome research 2016;150 (1):52-59 [PubMed]

2015

  • Cirulli Elizabeth T., Lasseigne Brittany N., Petrovski Slavé, Sapp Peter C., Dion Patrick A., Leblond Claire S., Couthouis Julien, Lu Yi-Fan, Wang Quanli, Krueger Brian J., Ren Zhong, Keebler Jonathan, Han Yujun, Levy Shawn E., Boone Braden E., Wimbish Jack R., Waite Lindsay L., Jones Angela L., Carulli John P., Day-Williams Aaron G., Staropoli John F., Xin Winnie W., Chesi Alessandra, Raphael Alya R., McKenna-Yasek Diane, Cady Janet, de Jong J. M. B. Vianney, Kenna Kevin P., Smith Bradley N., Topp Simon, Miller Jack, Gkazi Athina, Al-Chalabi Ammar, van den Berg Leonard H., Veldink Jan, Silani Vincenzo, Ticozzi Nicola, Shaw Christopher E., Baloh Robert H., Appel Stanley, Simpson Ericka, Lagier-Tourenne Clotilde, Pulst Stefan M., Gibson Summer, Trojanowski John Q., Elman Lauren, McCluskey Leo, Grossman Murray, Baas Frank, ten Asbroek Anneloor L. M. A. Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways Science 2015;347 (6229):1436-1441 [PubMed]
  • Aronica Eleonora, Baas Frank, Iyer Anand, ten Asbroek Anneloor L. M. A., Morello Giovanna, Cavallaro Sebastiano Molecular classification of amyotrophic lateral sclerosis by unsupervised clustering of gene expression in motor cortex Neurobiology of disease 2015;74:359-376 [PubMed]

2014

  • Smith Bradley N., Ticozzi Nicola, Fallini Claudia, Gkazi Athina Soragia, Topp Simon, Kenna Kevin P., Scotter Emma L., Kost Jason, Keagle Pamela, Miller Jack W., Calini Daniela, Vance Caroline, Danielson Eric W., Troakes Claire, Tiloca Cinzia, Al-Sarraj Safa, Lewis Elizabeth A., King Andrew, Colombrita Claudia, Pensato Viviana, Castellotti Barbara, de Belleroche Jacqueline, Baas Frank, ten Asbroek Anneloor L. M. A., Sapp Peter C., McKenna-Yasek Diane, McLaughlin Russell L., Polak Meraida, Asress Seneshaw, Esteban-Pérez Jesús, Muñoz-Blanco José Luis, Simpson Michael, van Rheenen Wouter, Diekstra Frank P., Lauria Giuseppe, Duga Stefano, Corti Stefania, Cereda Cristina, Corrado Lucia, Sorarù Gianni, Morrison Karen E., Williams Kelly L., Nicholson Garth A., Blair Ian P., Dion Patrick A., Leblond Claire S., Rouleau Guy A., Hardiman Orla, Veldink Jan H., van den Berg Leonard H. Exome-wide rare variant analysis identifies TUBA4A mutations associated with familial ALS Neuron 2014;84 (2):324-331 [PubMed]

2013

  • Smith Bradley N., Newhouse Stephen, Shatunov Aleksey, Vance Caroline, Topp Simon, Johnson Lauren, Miller Jack, Lee Younbok, Troakes Claire, Scott Kirsten M., Jones Ashley, Gray Ian, Wright Jamie, Hortobágyi Tibor, Al-Sarraj Safa, Rogelj Boris, Powell John, Lupton Michelle, Lovestone Simon, Sapp Peter C., Weber Markus, Nestor Peter J., Schelhaas Helenius J., ten Asbroek A. A., Silani Vincenzo, Gellera Cinzia, Taroni Franco, Ticozzi Nicola, van den Berg Leonard, Veldink Jan, van Damme Phillip, Robberecht Wim, Shaw Pamela J., Kirby Janine, Pall Hardev, Morrison Karen E., Morris Alex, de Belleroche Jacqueline, de Jong J. M. B. Vianney, Baas Frank, Andersen Peter M., Landers John, Brown Robert H., Weale Michael E., Al-Chalabi Ammar, Shaw Christopher E. The C9ORF72 expansion mutation is a common cause of ALS+/-FTD in Europe and has a single founder European journal of human genetics 2013;21 (1):102-108 [PubMed]

2011

  • Verhamme Camiel, King Rosalind H. M., ten Asbroek Anneloor L. M. A., Muddle John R., Nourallah Michelle, Wolterman Ruud, Baas Frank, van Schaik Ivo N. Myelin and Axon Pathology in a Long-Term Study of PMP22-Overexpressing Mice Journal of neuropathology and experimental neurology 2011;70 (5):386-398 [PubMed]

2010

  • Meyer Zu Hörste Gerd, Heidenreich Holger, Mausberg Anne K., Lehmann Helmar C., ten Asbroek Anneloor L. M. A., Saavedra José T., Baas Frank, Hartung Hans-Peter, Wiendl Heinz, Kieseier Bernd C. Mouse Schwann cells activate MHC class I and II restricted T-cell responses, but require external peptide processing for MHC class II presentation Neurobiology of disease 2010;37 (2):483-490 [PubMed]

2008

  • Saavedra José T., Wolterman Ruud A., Baas Frank, ten Asbroek Anneloor L. M. A. Myelination competent conditionally immortalized mouse Schwann cells Journal of neuroscience methods 2008;174 (1):25-30 [PubMed]

2006

  • ten Asbroek Anneloor L. M. A., van Ruissen Fred, Ruijter Jan M., Baas Frank Comparison of Schwann cell and sciatic nerve transcriptomes indicates that mouse is a valid model for the human peripheral nervous system Journal of neuroscience research 2006;84 (3):542-552 [PubMed]

2005

  • ten Asbroek Anneloor L. M. A., Verhamme Camiel, van Groenigen Marjon, Wolterman Ruud, de Kok-Nazaruk Maryla M., Baas Frank Expression profiling of sciatic nerve in a Charcot-Marie-Tooth disease type 1a mouse model Journal of neuroscience research 2005;79 (6):825-835 [PubMed]

2003

  • Fluiter Kees, ten Asbroek Anneloor L. M. A., de Wissel Marit B., Jakobs Marja E., Wissenbach Margit, Olsson Håkan, Olsen Otto, Oerum Henrik, Baas Frank In vivo tumor growth inhibition and biodistribution studies of locked nucleic acid (LNA) antisense oligonucleotides Nucleic acids research 2003;31 (3):953-962 [PubMed]
  • Fluiter K., Housman D., ten Asbroek A. L. M. A., Baas F. Killing cancer by targeting genes that cancer cells have lost: Allele-specific inhibition, a novel approach to the treatment of genetic disorders Cellular and molecular life sciences 2003;60 (5):834-843 [PubMed]

2002

  • ten Asbroek A. L. M. A. Allele specific inhibition. A novel approach to cancer therapy 2002. 143p. ISBN 9789090157856. [UvA Dissertations Online] University of Amsterdam. (Supervisor: de Jong J. M. B. V.; Co-supervisor: Baas F.)
  • ten Asbroek Anneloor L. M. A., van Groenigen Marjon, Jakobs Marja E., Koevoets Cindy, Janssen Bert, Baas Frank Ribonuclease H1 maps to chromosome 2 and has at least three pseudogene loci in the human genome Genomics 2002;79 (6):818-823 [PubMed]
  • ten Asbroek Anneloor L. M. A., van Groenigen Marjon, Nooij Marleen, Baas Frank The involvement of human ribonucleases H1 and H2 in the variation of response of cells to antisense phosphorothioate oligonucleotides European Journal of Biochemistry / FEBS 2002;269 (2):583-592 [PubMed]
  • Fluiter Kees, ten Asbroek Anneloor L. M. A., van Groenigen Marjon, Nooij Marleen, Aalders Maurice C. G., Baas Frank Tumor genotype-specific growth inhibition in vivo by antisense oligonucleotides against a polymorphic site of the large subunit of human RNA polymerase II Cancer research 2002;62 (7):2024-2028 [PubMed]

2001

  • ten Asbroek A. L., Olsen J., Housman D., Baas F., Stanton V. Genetic variation in mRNA coding sequences of highly conserved genes Physiological genomics 2001;5 (3):113-118 [PubMed]

2000

  • ten Asbroek A. L., Fluiter K., van Groenigen M., Nooij M., Baas F. Polymorphisms in the large subunit of human RNA polymerase II as target for allele-specific inhibition Nucleic acids research 2000;28 (5):1133-1138 [PubMed]

1999

  • Hafezparast M., Witherden A., Nicholson S., Bermingham N., Mackin J., ten Asbroek A., Ball S., Peters J., Baas F., Martin J. E., Fisher E. M. The kinesin light chain gene: its mapping and exclusion in mouse and human forms of inherited motor neuron degeneration Neuroscience letters 1999;273 (1):49-52 [PubMed]

1997

  • Motley A. M., Hettema E. H., Hogenhout E. M., Brites P., ten Asbroek A. L., Wijburg F. A., Baas F., Heijmans H. S., Tabak H. F., Wanders R. J., Distel B. Rhizomelic chondrodysplasia punctata is a peroxisomal protein targeting disease caused by a non-functional PTS2 receptor Nature genetics 1997;15 (4):377-380 [PubMed]

1993

  • ten Asbroek A. L., Mol C. A., Kieft R., Borst P. Stable transformation of Trypanosoma brucei Molecular and biochemical parasitology 1993;59 (1):133-142 [PubMed]

1990

  • Borst P., Gommers-Ampt J. H., Lutgerink J., Ouellette M., ten Asbroek A. L., Zomerdijk J. C. Control of surface antigen genes in African trypanosomes Biochemical Society transactions 1990;18 (5):741-742 [PubMed]
  • ten Asbroek A. L., Ouellette M., Borst P. Targeted insertion of the neomycin phosphotransferase gene into the tubulin gene cluster of Trypanosoma brucei Nature 1990;348 (6297):174-175 [PubMed]
  • Zomerdijk J. C., Ouellette M., ten Asbroek A. L., Kieft R., Bommer A. M., Clayton C. E., Borst P. The promoter for a variant surface glycoprotein gene expression site in Trypanosoma brucei EMBO journal 1990;9 (9):2791-2801 [PubMed]

1987

  • Cordewener J., ten Asbroek A., Wassink H., Eady R., Haaker H., Veeger C. Binding of ADP and orthophosphate during the ATPase reaction of nitrogenase European Journal of Biochemistry / FEBS 1987;162 (2):265-270 [PubMed]
  • Laird P. W., ten Asbroek A. L., Borst P. Controlled turnover and 3' trimming of the trans splicing precursor of Trypanosoma brucei Nucleic acids research 1987;15 (24):10087-10103 [PubMed]