H. Peters Sengers MSc PhD publications

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Publications MSc PhD H. Peters Sengers

Positions
Other Academic Staff, Research Associate
Main activities
Research
Specialisation
Clinical Epidemiology
Focus of research

Since September 2017, I started to work as a postdoctoral clinical epidemiologist in the group of prof. dr. Tom van der Poll. My project will entail data analyses linking clinical and molecular data including validation of already discovered RNA biomarkers for sepsis in independent patient groups, and discovery of new sepsis biomarkers focusing on messenger RNA’s. I intend to use the Molecular Diagnosis and Risk Stratification of Sepsis (MARS) database, a prospective cohort study including 8113 patients admitted to the intensive care units (ICUs) of two Dutch tertiary teaching hospitals. My key projects include:

1) To predict key variables associated with organ dysfunction 24-48 hours ahead of time in critically ill patients admitted to the ICU. Being able to predict organ dysfunction ahead of time will assist physicians in preempting severe organ dysfunction, and thereby aiding in the clinical decision process earlier in the course of ICU treatment.

2) Finding a molecular host response assay for sepsis. This could aid phycisians in tailoring antibiotic treatment to critically ill patients admitted to the ICU.

 

2020

  • Singh Ramandeep, Peters-Sengers Hessel, Remmerswaal Ester B. M., Yapici Unsal, van der Pant Karlijn A. M. I., van der Weerd Neelke C., Roelofs Joris J. T. H., van Lier René A. W., Bemelman Fréderike J., Florquin Sandrine, ten Berge Ineke J. M. Clinical consequences of primary CMV infection after renal transplantation: a case–control study Transplant international 2020;33 (9):1116-1127 [PubMed]
  • Kers Jesper, Peters-Sengers Hessel, Heemskerk Martin B. A., Berger Stefan P., Betjes Michiel G. H., van Zuilen Arjan D., Hilbrands Luuk B., de Fijter Johan W., Nurmohamed Azam S., Christiaans Maarten H., Homan van der Heide Jaap J., Debray Thomas P. A., Bemelman Fréderike J. Erratum: Prediction models for delayed graft function: External validation on the Dutch Prospective Renal Transplantation Registry (Nephrology Dialysis Transplantation (2018) (gfy019) DOI: 10.1093/ndt/gfy019) Nephrology, dialysis, transplantation 2020;35 (7):1277 [PubMed]
  • Olde Engberink Rik H. G., van den Born Bert-Jan H., Peters-Sengers Hessel, Vogt Liffert Long-term potassium intake and associated renal and cardiovascular outcomes in the clinical setting Clinical nutrition (Edinburgh, Scotland) 2020;39 (12):3671-3676 [PubMed]
  • Uhel Fabrice, Peters-Sengers Hessel, Falahi Fahimeh, Scicluna Brendon P., van Vught Lonneke A., Bonten Marc J., Cremer Olaf L., Schultz Marcus J., van der Poll Tom Mortality and host response aberrations associated with transient and persistent acute kidney injury in critically ill patients with sepsis: a prospective cohort study Intensive care medicine 2020;46 (8):1576-1589 [PubMed]
  • Jara-Palomares Luis, Solier-López Aurora, Russo Mariaconcetta, Suñer Marta, González-Roncero Francisco, Peters-Sengers Hessel, Middeldorp Saskia, Bemelman Frederike J., Barco Stefano Thromboprophylaxis after renal transplantation and patient risk stratification: The case of mTOR inhibitors Thrombosis research 2020;195:100-102 [PubMed]

2019

  • Terpstra Matty L., Sinnige Marjan J., Hugenholtz Floor, Peters-Sengers Hessel, Remmerswaal Ester B. M., Geerlings Suzanne E., Bemelman Frederike J. Butyrate production in patients with end-stage renal disease International Journal of Nephrology and Renovascular Disease 2019;12:87-101 [PubMed]
  • Peters-Sengers Hessel, Houtzager Julia H E, Idu Mirza M, Heemskerk Martin B A, van Heurn Ernst L W, Homan van der Heide Jaap J, Kers Jesper, Berger Stefan P, van Gulik Thomas M, Bemelman Frederike J Impact of Cold Ischemia Time on Outcomes of Deceased Donor Kidney Transplantation: An Analysis of a National Registry Transplantation direct 2019;5 (5):e448 [PubMed]
  • Garrelfs Sander F., Rumsby Gill, Peters-Sengers Hessel, Erger Florian, Groothoff Jaap W., Beck Bodo B., Oosterveld Michiel J. S., Pelle Alessandra, Neuhaus Thomas, Adams Brigitte, Cochat Pierre, Salido Eduardo, Lipkin Graham W., Hoppe Bernd, Hulton Sally-Anne Patients with primary hyperoxaluria type 2 have significant morbidity and require careful follow-up Kidney international 2019;96 (6):1389-1399 [PubMed]
  • Olde Engberink Rik H. G., van den Born Bert-Jan H., Peters-Sengers Hessel, Vogt Liffert Urinary sodium excretion measures and health outcomes Lancet 2019;393 (10178):1293-1294

2018

  • Peters Sengers Hessel Challenging frontiers in renal transplantation 2018. 237p. ISBN 9789462999817. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Bemelman F. J. , Homan van der Heide J. J.; Co-supervisors: Berger S. P., Heemskerk M. B. A.)
  • Peters-Sengers H., Houtzager J. H. E., Heemskerk M. B. A., Idu M. M., Minnee R. C., Klaasen R. W., Joor S. E., Hagenaars J. A. M., Rebers P. M., Homan van der Heide J. J., Roodnat J. I., Bemelman F. J. DCD Donor Hemodynamics as Predictor of Outcome After Kidney Transplantation American journal of transplantation 2018;18 (8):1966-1976 [PubMed]
  • Uhel Fabrice, Peters-Sengers Hessel, van der Poll Tom Initiation of renal replacement therapy in patients with sepsis: more to it than meets the eye Annals of translational medicine 2018;6 (Suppl 2):S130 [PubMed]
  • Kers Jesper, Peters-Sengers Hessel, Heemskerk Martin B. A., Berger Stefan P., Betjes Michiel G. H., van Zuilen Arjan D., Hilbrands Luuk B., de Fijter Johan W., Nurmohamed Azam S., Christiaans Maarten H., Homan van der Heide Jaap J., Debray Thomas P. A., Bemelman Fréderike J. Predicition models for delayed graft function: external validation on The Dutch Prospective Renal Transplantation Registry Nephrology, dialysis, transplantation 2018;33 (7):1259-1268 [PubMed]
  • Olde Engberink Rik H. G., van den Born Bert-Jan H., Peters-Sengers Hessel, Vogt Liffert Response by Olde Engberink et al to letter regarding article, "use of a single baseline versus multiyear 24-hour urine collection for estimation of long-term sodium intake and associated cardiovascular and renal risk" Circulation 2018;137 (14):1538-1539 [PubMed]
  • Peters-Sengers Hessel, Heemskerk Martin B. A., Geskus Ronald B., Kers Jesper, Homan van der Heide Jaap J., Berger Stefan P., Bemelman Frederike J. Validation of the Prognostic Kidney Donor Risk Index Scoring System of Deceased Donors for Renal Transplantation in the Netherlands Transplantation 2018;102 (1):162-170 [PubMed]

2017

  • Bemelman F. J., de Fijter J. W., Kers J., Meyer C., Peters-Sengers H., de Maar E. F., van der Pant K. A. M. I., de Vries A. P. J., Sanders J.-S., Zwinderman A., Idu M. M., Berger S., Reinders M. E. J., Krikke C., Bajema I. M., van Dijk M. C., ten Berge I. J. M., Ringers J., Lardy J., Roelen D., Moes D.-J., Florquin S., Homan van der Heide J. J. Early Conversion to Prednisolone/Everolimus as an Alternative Weaning Regimen Associates With Beneficial Renal Transplant Histology and Function: The Randomized-Controlled MECANO Trial American journal of transplantation 2017;17 (4):1020-1030 [PubMed]
  • Dobrowolski Linn C., van Huis Maike, van der Lee Johanna H., Peters Sengers Hessel, Liliën Marc R., Cransberg Karlien, Cornelissen Marlies, Bouts Antonia H., de Fijter Johan W., Berger Stefan P., van Zuilen Arjan, Nurmohamed Shaikh A., Betjes Michiel H. G., Hilbrands Luuk, Hoitsma Andries J., Bemelman Frederike J., Paul Krediet C. T., Groothoff Jaap W. Epidemiology and management of hypertension in paediatric and young adult kidney transplant recipients in The Netherlands : Erratum Nephrology, dialysis, transplantation 2017;32 (2):402 [PubMed]
  • Peters-Sengers Hessel, Homan van der Heide Jaap J., Heemskerk Martin B. A., ten Berge Ineke J. M., Ultee Fred C. W., Idu Mirza M., Betjes Michiel G. H., van Zuilen Arjan D., Christiaans Maarten H. L., Hilbrands Luuk H., de Vries Aiko P. J., Nurmohamed Azam S., Berger Stefan P., Bemelman Frederike J. Similar 5-Year Estimated Glomerular Filtration Rate Between Kidney Transplants From Uncontrolled and Controlled Donors After Circulatory Death-A Dutch Cohort Study Transplantation 2017;101 (6):1144-1151 [PubMed]
  • Peters-Sengers Hessel, Berger Stefan P., Heemskerk Martin B. A., Al Arashi Doaa, Homan van der Heide Jaap J., Hemke Aline C., ten Berge Ineke J. M., Idu Mirza M., Betjes Michiel G. H., van Zuilen Arjan D., Hilbrands Luuk B., de Vries Aiko P. J., Nurmohamed Azam S., Christiaans Maarten H., Ernest van Heurn L. W., de Fijter Johan W., Bemelman Frederike J. Stretching the Limits of Renal Transplantation in Elderly Recipients of Grafts from Elderly Deceased Donors Journal of the American Society of Nephrology 2017;28 (2):621-631 [PubMed]
  • Olde Engberink Rik H. G., van den Hoek Thomas C., van Noordenne Nicky D., van den Born Bert-Jan H., Peters-Sengers Hessel, Vogt Liffert Use of a Single Baseline Versus Multiyear 24-Hour Urine Collection for Estimation of Long-Term Sodium Intake and Associated Cardiovascular and Renal Risk Circulation 2017;136 (10):917-926 [PubMed]

2016

  • Dobrowolski Linn C., van Huis Maike, van der Lee Johanna H., Peters Sengers Hessel, Liliën Marc R., Cransberg Karlien, Cornelissen Marlies, Bouts Antonia H., de Fijter Johan W., Berger Stefan P., van Zuilen Arjan, Nurmohamed Shaikh A., Betjes Michiel H. G., Hilbrands Luuk, Hoitsma Andries J., Bemelman Frederike J., Krediet Paul, Groothoff Jaap W. Epidemiology and management of hypertension in paediatric and young adult kidney transplant recipients in The Netherlands Nephrology, dialysis, transplantation 2016;31 (11):1947-1956 [PubMed]
  • Singh R., Geerlings S. E., Peters-Sengers H., Idu M. M., Hodiamont C. J., ten Berge I. J. M., Bemelman F. J. Incidence, risk factors, and the impact of allograft pyelonephritis on renal allograft function Transplant infectious disease 2016;18 (5):647-660 [PubMed]