A.T. Das PhD publications

2020

• Binda Caroline S., Klaver Bep, Berkhout Ben, Das Atze T. CRISPR-Cas9 Dual-gRNA Attack Causes Mutation, Excision and Inversion of the HIV-1 Proviral DNA Viruses 2020;12 (3) [PubMed]
• Gao Zongliang, Fan Minghui, Das Atze T., Herrera-Carrillo Elena, Berkhout Ben Extinction of all infectious HIV in cell culture by the CRISPR-Cas12a system with only a single crRNA Nucleic acids research 2020;48 (10):5527-5539 [PubMed]
• Chen Jianbo, Umunnakwe Chijioke, Sun David Q., Nikolaitchik Olga A., Pathak Vinay K., Berkhout Ben, Das Atze T., Hu Wei-Shau Impact of Nuclear Export Pathway on Cytoplasmic HIV-1 RNA Transport Mechanism and Distribution mBio 2020;11 (6):1-18 [PubMed]

2019

• Das Atze T., Binda Caroline S., Berkhout Ben Elimination of infectious HIV DNA by CRISPR–Cas9 Current opinion in virology 2019;38:81-88 [PubMed]
• Turrini Filippo, Saliu Fabio, Forlani Greta, Das Atze T., van Lint Carine, Accolla Roberto S., Berkhout Ben, Poli Guido, Vicenzi Elisa Interferon-inducible TRIM22 contributes to maintenance of HIV-1 proviral latency in T cell lines Virus research 2019;269 [PubMed]
• Das Atze T., Pasternak Alexander O., Berkhout Ben On the generation of the MSD class of defective HIV proviruses Retrovirology 2019;16 (1) [PubMed]
• Darcis Gilles, Binda Caroline S., Klaver Bep, Herrera-Carrillo Elena, Berkhout Ben, Das Atze T. The impact of HIV-1 genetic diversity on CRISPR-Cas9 antiviral activity and viral escape Viruses 2019;11 (3) [PubMed]

2018

• Wang Gang, Zhao Na, Berkhout Ben, Das Atze T. CRISPR-Cas based antiviral strategies against HIV-1 Virus research 2018;244:321-332 [PubMed]
• Wang Gang CRISPR-Cas based strategies against HIV-1 2018. 135p. ISBN 9789462998162. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Berkhout B.; Co-supervisor: Das A. T.)
• Das Atze T., Berkhout Ben How polypurine tract changes in the HIV-1 RNA genome can cause resistance against the integrase inhibitor dolutegravir mBio 2018;9 (2) [PubMed]
• Darcis Gilles, Das Atze T., Berkhout Ben Tackling HIV persistence: pharmacological versus CRISPR-based shock strategies Viruses 2018;10 (4) [PubMed]
• Mueller Nancy, Pasternak Alexander O., Klaver Bep, Cornelissen Marion, Berkhout Ben, Das Atze T. The HIV-1 tat protein enhances splicing at the major splice donor site Journal of virology 2018;92 (14) [PubMed]

2017

• Zhao Na, Wang Gang, Das Atze T., Berkhout Ben Combinatorial CRISPR-Cas9 and RNA Interference Attack on HIV-1 DNA and RNA Can Lead to Cross-Resistance Antimicrobial agents and chemotherapy 2017;61 (12):e01486-17 [PubMed]
• Morin Aurélie, Ruggiero Carmen, Robidel Estelle, Doghman-Bouguerra Mabrouka, Das Atze T., Castellano Rémy, Josselin Emmanuelle, Favier Judith, Lalli Enzo Establishment of a mouse xenograft model of metastatic adrenocortical carcinoma Oncotarget 2017;8 (31):51050-51057 [PubMed]

2016

• Wang Gang, Zhao Na, Berkhout Ben, Das Atze T. A Combinatorial CRISPR-Cas9 Attack on HIV-1 DNA Extinguishes All Infectious Provirus in Infected T Cell Cultures Cell reports 2016;17 (11):2819-2826 [PubMed]
• Mueller Nancy, Das Atze T., Berkhout Ben A Phylogenetic Survey on the Structure of the HIV-1 Leader RNA Domain That Encodes the Splice Donor Signal Viruses 2016;8 (7):200 [PubMed]
• Chtarto Abdelwahed, Humbert-Claude Marie, Bockstael Olivier, Das Atze T., Boutry Sébastien, Breger Ludivine S., Klaver Bep, Melas Catherine, Barroso-Chinea Pedro, Gonzalez-Hernandez Tomas, Muller Robert N., DeWitte Olivier, Levivier Marc, Lundberg Cecilia, Berkhout Ben, Tenenbaum Liliane A regulatable AAV vector mediating GDNF biological effects at clinically-approved sub-antimicrobial doxycycline doses Molecular therapy. Methods & clinical development 2016;5:16027 [PubMed]
• Das Atze T., Berkhout Ben Conditionally replicating HIV and SIV variants Virus research 2016;216:66-75 [PubMed]
• van der Velden Yme U., Kleibeuker Wendy, Harwig Alex, Klaver Bep, Siteur-Van Rijnstra Esther, Frankin Esmay, Berkhout Ben, Das Atze T. Construction of Nef-positive doxycycline-dependent HIV-1 variants using bicistronic expression elements Virology 2016;488:96-107 [PubMed]
• Liang Chen, Wainberg Mark A., Das Atze T., Berkhout Ben CRISPR/Cas9: a double-edged sword when used to combat HIV infection Retrovirology 2016;13 (1):37 [PubMed]
• Wang Gang, Zhao Na, Berkhout Ben, Das Atze T. CRISPR-Cas9 Can Inhibit HIV-1 Replication but NHEJ Repair Facilitates Virus Escape Molecular therapy 2016;24 (3):522-526 [PubMed]
• Müller Nancy Regulation of HIV-1 splicing 2016. 155p. ISBN 9789461826121. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Berkhout B.; Co-supervisor: Das A. T.)
• Berry Neil, Manoussaka Maria, Ham Claire, Ferguson Deborah, Tudor Hannah, Mattiuzzo Giada, Klaver Bep, Page Mark, Stebbings Richard, Das Atze T., Berkhout Ben, Almond Neil, Cranage Martin P. Role of Occult and Post-acute Phase Replication in Protective Immunity Induced with a Novel Live Attenuated SIV Vaccine PLoS pathogens 2016;12 (12):e1006083 [PubMed]
• Das Atze T., Zhou Xue, Metz Stefan W., Vink Monique A., Berkhout Ben Selecting the optimal Tet-On system for doxycycline-inducible gene expression in transiently transfected and stably transduced mammalian cells Biotechnology journal 2016;11 (1):71-79 [PubMed]
• Harwig Alex, Jongejan Aldo, van Kampen Antoine H. C., Berkhout Ben, Das Atze T. Tat-dependent production of an HIV-1 TAR-encoded miRNA-like small RNA Nucleic acids research 2016;44 (9):4340-4353 [PubMed]
• Das Atze T., Tenenbaum Liliane, Berkhout Ben Tet-On Systems For Doxycycline-inducible Gene Expression Current gene therapy 2016;16 (3):156-167 [PubMed]

2015

• Harwig Alex HIV-1 in the RNA world: Transcription regulation, miRNAs and antiviral RNAs 2015. 186p. ISBN 9789461825377. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Berkhout B.; Co-supervisor: Das A. T.)
• Harwig Alex, Das Atze T., Berkhout Ben HIV-1 RNAs: sense and antisense, large mRNAs and small siRNAs and miRNAs Current opinion in HIV and AIDS 2015;10 (2):103-109 [PubMed]
• Mueller Nancy, Berkhout Ben, Das Atze T. HIV-1 splicing is controlled by local RNA structure and binding of splicing regulatory proteins at the major 5' splice site Journal of general virology 2015;96 (Part 7):1906-1917 [PubMed]
• Turrini Filippo, Marelli Sara, Kajaste-Rudnitski Anna, Lusic Marina, van Lint Carine, Das Atze T., Harwig Alex, Berkhout Ben, Vicenzi Elisa HIV-1 transcriptional silencing caused by TRIM22 inhibition of Sp1 binding to the viral promoter Retrovirology 2015;12 (1):104 [PubMed]
• Mueller Nancy, Klaver Bep, Berkhout Ben, Das Atze T. Human immunodeficiency virus type 1 splicing at the major splice donor site is controlled by highly conserved RNA sequence and structural elements Journal of general virology 2015;96 (11):3389-3395 [PubMed]
• Berkhout Ben, Das Atze T. On the primer binding site mutation that appears and disappears during HIV and SIV replication Retrovirology 2015;12:75 [PubMed]
• van Bel Nikki Structure and sequence motifs in the HIV-1 RNA genome 2015. 177p. ISBN 9789461825360. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Berkhout B.; Co-supervisor: Das A. T.)
• van Bel Nikki, Ghabri Anouar, Das Atze T., Berkhout Ben The HIV-1 leader RNA is exquisitely sensitive to structural changes Virology 2015;483:236-252 [PubMed]

2014

• van Bel Nikki, Das Atze T., Cornelissen Marion, Abbink Truus E. M., Berkhout Ben A short sequence motif in the 5' leader of the HIV-1 genome modulates extended RNA dimer formation and virus replication Journal of biological chemistry 2014;289 (51):35061-35074 [PubMed]
• Mueller Nancy, van Bel Nikki, Berkhout Ben, Das Atze T. HIV-1 splicing at the major splice donor site is restricted by RNA structure Virology 2014;468-470:609-620 [PubMed]
• van Bel Nikki, Das Atze T., Berkhout Ben In Vivo SELEX of Single-Stranded Domains in the HIV-1 Leader RNA Journal of virology 2014;88 (4):1870-1880 [PubMed]
• Harwig Alex, Das Atze T., Berkhout Ben Retroviral microRNAs Current opinion in virology 2014;7:47-54 [PubMed]
• de Vree Paula J. P., de Wit Elzo, Yilmaz Mehmet, van de Heijning Monique, Klous Petra, Verstegen Marjon J. A. M., Wan Yi, Teunissen Hans, Krijger Peter H. L., Geeven Geert, Eijk Paul P., Sie Daoud, Ylstra Bauke, Hulsman Lorette O. M., van Dooren Marieke F., van Zutven Laura J. C. M., van den Ouweland Ans, Verbeek Sjef, van Dijk Ko Willems, Cornelissen Marion, Das Atze T., Berkhout Ben, Sikkema-Raddatz Birgit, van den Berg Eva, van der Vlies Pieter, Weening Desiree, den Dunnen Johan T., Matusiak Magdalena, Lamkanfi Mohamed, Ligtenberg Marjolijn J. L., ter Brugge Petra, Jonkers Jos, Foekens John A., Martens John W., van der Luijt Rob, van Amstel Hans Kristian Ploos, van Min Max, Splinter Erik, de Laat Wouter Targeted sequencing by proximity ligation for comprehensive variant detection and local haplotyping Nature biotechnology 2014;32 (10):1019-1025 [PubMed]
• van Bel Nikki, van der Velden Yme, Bonnard Damien, Le Rouzic Erwann, Das Atze T., Benarous Richard, Berkhout Ben The allosteric HIV-1 integrase inhibitor BI-D affects virion maturation but does not influence packaging of a functional RNA genome PLoS ONE 2014;9 (7):e103552 [PubMed]

2013

• van der Velden Gisela J., Vink Monique A., Klaver Bep, Das Atze T., Berkhout Ben An AUG codon upstream of rev and env open reading frames ensures optimal translation of the simian immunodeficiency virus Env protein Virology 2013;436 (1):191-200 [PubMed]
• Manoussaka Maria S., Berry Neil, Ferguson Deborah, Stebbings Richard, Robinson Mark, Ham Claire, Page Mark, Li Bo, Das Atze T., Berkhout Ben, Almond Neil, Cranage Martin P. Conditionally-live attenuated SIV upregulates global T effector memory cell frequency under replication permissive conditions Retrovirology 2013;10 (1):59 [PubMed]
• van der Velden Gisela J. In vitro and in vivo testing of conditionally replicating SIV and HIV-1 strains to study viral gene expression 2013. 160p. ISBN 9789462032699. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Berkhout B.; Co-supervisor: Das A. T.)

2012

• Legrand Nicolas, van der Velden Gisela J., Fang Raphaël Ho Tsong, Douaisi Marc, Weijer Kees, Das Atze T., Blom Bianca, Uittenbogaart Christel H., Berkhout Ben, Centlivre Mireille A doxycycline-dependent human immunodeficiency virus type 1 replicates in vivo without inducing CD4(+) T-cell depletion Journal of general virology 2012;93 (9):2017-2027 [PubMed]
• Berkhout Ben, Das Atze T. HIV-1 Escape From RNAi Antivirals: Yet Another Houdini Action? Molecular therapy. Nucleic acids 2012;1 (6):e26 [PubMed]
• Das Atze T., Vrolijk Martine M., Harwig Alex, Berkhout Ben Opening of the TAR hairpin in the HIV-1 genome causes aberrant RNA dimerization and packaging Retrovirology 2012;9 (1):59 [PubMed]
• van der Velden Gisela J., Vink Monique A., Berkhout Ben, Das Atze T. Tat has a dual role in simian immunodeficiency virus transcription Journal of general virology 2012;93 (10):2279-2289 [PubMed]
• van der Velden Gisela J., Klaver Bep, Das Atze T., Berkhout Ben Upstream AUG Codons in the Simian Immunodeficiency Virus SIVmac239 Genome Regulate Rev and Env Protein Translation Journal of virology 2012;86 (22):12362-12371 [PubMed]

2011

• Das Atze T., Harwig Alex, Berkhout Ben The HIV-1 Tat protein has a versatile role in activating viral transcription Journal of virology 2011;85 (18):9506-9516 [PubMed]

2010

• Centlivre M., Zhou X., Pouw S. M., Weijer K., Kleibeuker W., Das A. T., Blom B., Seppen J., Berkhout B., Legrand N. Autoregulatory lentiviral vectors allow multiple cycles of doxycycline-inducible gene expression in human hematopoietic cells in vivo Gene therapy 2010;17 (1):14-25 [PubMed]
• Das Atze T., Berkhout Ben HIV-1 evolution: frustrating therapies, but disclosing molecular mechanisms Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2010;365 (1548):1965-1973 [PubMed]
• Das Atze T., Jeeninga Rienk E., Berkhout Ben Possible applications for replicating HIV 1 vectors HIV therapy 2010;4 (3):361-369 [PubMed]
• Vrolijk Martine M. Structure and function of the repeat region in the HIV-1 RNA genome 2010. 111p. ISBN 9789090250151. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Berkhout B.; Co-supervisor: Das A. T.)

2009

• Kleibeuker Wendy, Zhou Xue, Centlivre Mireille, Legrand Nicolas, Page Mark, Almond Neil, Berkhout Ben, Das Atze T. A Sensitive Cell-Based Assay to Measure the Doxycycline Concentration in Biological Samples Human gene therapy 2009;20 (5):524-530 [PubMed]
• Vrolijk Martine M., Harwig Alex, Berkhout Ben, Das Atze T. Destabilization of the TAR hairpin leads to extension of the polyA hairpin and inhibition of HIV-1 polyadenylation Retrovirology 2009;6 (1):13 [PubMed]
• Berkhout Ben, Das Atze T. Virus Evolution as a Tool to Study HIV-1 Biology Methods in molecular biology (Clifton, N.J.) 2009;485:436-451 [PubMed]

2008

• Vrolijk Martine M., Ooms Marcel, Harwig Alex, Das Atze T., Berkhout Ben Destabilization of the TAR hairpin affects the structure and function of the HIV-1 leader RNA Nucleic acids research 2008;36 (13):4352-4363 [PubMed]
• Centlivre Mireille, Klaver Bep, Berkhout Ben, Das Atze T. Functional analysis of the complex trans-activating response element RNA structure in simian immunodeficiency virus Journal of virology 2008;82 (18):9171-9178 [PubMed]
• Das Atze T., Klaver Bep, Centlivre Mireille, Harwig Alex, Ooms Marcel, Page Mark, Almond Neil, Yuan Fang, Piatak Mike, Lifson Jeffrey D., Berkhout Ben Optimization of the doxycycline-dependent simian immunodeficiency virus through in vitro evolution Retrovirology 2008;5 (1):44 [PubMed]

2007

• Das Atze T., Klaver Bep, Harwig Alex, Vink Monique, Ooms Marcel, Centlivre Mireille, Berkhout Ben Construction of a doxycycline-dependent simian immunodeficiency virus reveals a nontranscriptional function of tat in viral replication Journal of virology 2007;81 (20):11159-11169 [PubMed]
• Hoogenkamp Maarten, Gaemers Ingrid C., Schoneveld Onard J. L. M., Das Atze T., Grange Thierry, Lamers Wouter H. Hepatocyte-specific interplay of transcription factors at the far-upstream enhancer of the carbamoylphosphate synthetase gene upon glucocorticoid induction FEBS journal 2007;274 (1):37-45 [PubMed]
• Zhou Xue, Symons Jori, Hoppes Rieuwert, Krueger Christel, Berens Christian, Hillen Wolfgang, Berkhout Ben, Das Atze T. Improved single-chain transactivators of the Tet-On gene expression system BMC biotechnology 2007;7:6 [PubMed]
• Zhou Xue Optimization of the conditional-live HIV-1 vaccine strain 2007. 113p. ISBN 9789090214689. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Berkhout Ben; Co-supervisor: Das Atze T.)
• Das Atze T., Harwig Alex, Vrolijk Martine M., Berkhout Ben The TAR hairpin of human immunodeficiency virus type 1 can be deleted when not required for Tat-mediated activation of transcription Journal of virology 2007;81 (14):7742-7748 [PubMed]

2006

• Westerhout Ellen M., Vink Monique, Haasnoot P. C. Joost, Das Atze T., Berkhout Ben A conditionally replicating HIV-based vector that stably expresses an antiviral shRNA against HIV-1 replication Molecular therapy 2006;14 (2):268-275 [PubMed]
• Lützelberger Martin, Reinert Line S., Das Atze T., Berkhout Ben, Kjems Jørgen A novel splice donor site in the gag-pol gene is required for HIV-1 RNA stability Journal of biological chemistry 2006;281 (27):18644-18651 [PubMed]
• Ruijter Jan M., Thygesen Helene H., Schoneveld Onard J. L. M., Das Atze T., Berkhout Ben, Lamers Wouter H. Factor correction as a tool to eliminate between-session variation in replicate experiments: application to molecular biology and retrovirology Retrovirology 2006;3 (jan 6):2 [PubMed]
• Konstantinova Pavlina, de Haan Peter, Das Atze T., Berkhout Ben Hairpin-induced tRNA-mediated (HITME) recombination in HIV-1 Nucleic acids research 2006;34 (8):2206-2218 [PubMed]
• Zhou Xue, Vink Monique, Berkhout Ben, Das Atze T. Modification of the Tet-On regulatory system prevents the conditional-live HIV-1 variant from losing doxycycline-control Retrovirology 2006;3:82 [PubMed]
• Zhou X., Vink M., Klaver B., Berkhout B., Das A. T. Optimization of the Tet-On system for regulated gene expression through viral evolution Gene therapy 2006;13 (19):1382-1390 [PubMed]
• Zhou Xue, Vink Monique, Klaver Bep, Verhoef Koen, Marzio Giuseppe, Das Atze T., Berkhout Ben The genetic stability of a conditional live HIV-1 variant can be improved by mutations in the Tet-On regulatory system that restrain evolution Journal of biological chemistry 2006;281 (25):17084-17091 [PubMed]

2005

• Das Atze T., Vink Monique, Berkhout Ben Alternative tRNA priming of human immunodeficiency virus type 1 reverse transcription explains sequence variation in the primer-binding site that has been attributed to APOBEC3G activity Journal of virology 2005;79 (5):3179-3181 [PubMed]
• Markusic David, Oude-Elferink Ronald, Das Atze T., Berkhout Ben, Seppen Jurgen Comparison of single regulated lentiviral vectors with rtTA expression driven by an autoregulatory loop or a constitutive promoter Nucleic acids research 2005;33 (6):e63 [PubMed]
• Westerhout Ellen M., Ooms Marcel, Vink Monique, Das Atze T., Berkhout Ben HIV-1 can escape from RNA interference by evolving an alternative structure in its RNA genome Nucleic acids research 2005;33 (2):796-804 [PubMed]
• Das Atze T., Baldwin Chris E., Vink Monique, Berkhout Ben Improving the safety of a conditional-live human immunodeficiency virus type 1 vaccine by controlling both gene expression and cell entry Journal of virology 2005;79 (6):3855-3858 [PubMed]

2004

• Das Atze T., Verhoef Koen, Berkhout Ben A conditionally replicating virus as a novel approach toward an HIV vaccine Methods in enzymology 2004;388:359-379 [PubMed]
• Huthoff Hendrik, Das Atze T., Vink Monique, Klaver Bep, Zorgdrager Fokla, Cornelissen Marion, Berkhout Ben A human immunodeficiency virus type 1-infected individual with low viral load harbors a virus variant that exhibits an in vitro RNA dimerization defect Journal of virology 2004;78 (9):4907-4913 [PubMed]
• Kiselyeva Yana, Ito Yoshinori, Lima Rosangela G., Grivel Jean-Charles, Das Atze T., Berkhout Ben, Margolis Leonid B. Depletion of CD4 T lymphocytes in human lymphoid tissue infected ex vivo with doxycycline-dependent HIV-1 Virology 2004;328 (1):1-6 [PubMed]
• Das Atze T., Brummelkamp Thijn R., Westerhout Ellen M., Vink Monique, Madiredjo Mandy, Bernards René, Berkhout Ben Human immunodeficiency virus type 1 escapes from RNA interference-mediated inhibition Journal of virology 2004;78 (5):2601-2605 [PubMed]
• Schoneveld Onard J. L. M., Gaemers Ingrid C., Das Atze T., Hoogenkamp Maarten, Renes Johan, Ruijter Jan M., Lamers Wouter H. Structural requirements of the glucocorticoid-response unit of the carbamoyl-phosphate synthase gene Biochemical journal 2004;382 (Part 2):463-470 [PubMed]
• Das Atze T., Zhou Xue, Vink Monique, Klaver Bep, Verhoef Koen, Marzio Giuseppe, Berkhout Ben Viral evolution as a tool to improve the tetracycline-regulated gene expression system Journal of biological chemistry 2004;279 (18):18776-18782 [PubMed]

2003

• Kulinski Tadeusz, Olejniczak Mikolaj, Huthoff Hendrik, Bielecki Lukasz, Pachulska-Wieczorek Katarzyna, Das Atze T., Berkhout Ben, Adamiak Ryszard W. The apical loop of the HIV-1 TAR RNA hairpin is stabilized by a cross-loop base pair Journal of biological chemistry 2003;278 (40):38892-38901 [PubMed]

2002

• Das Atze T., Zhou Xue, Vink Monique, Klaver Bep, Berkhout Ben Conditional live virus as a novel approach towards a safe live attenuated HIV vaccine Expert review of vaccines 2002;1 (3):293-301 [PubMed]
• Berkhout Ben, Verhoef Koen, Marzio Giuseppe, Klaver Bep, Vink Monique, Zhou Xue, Das Atze T. Conditional virus replication as an approach to a safe live attenuated human immunodeficiency virus vaccine Journal of neurovirology 2002;8 (Suppl. 2):134-137 [PubMed]

2001

• Berkhout B., Das A. T., Beerens N. HIV-1 RNA editing, hypermutation, and error-prone reverse transcription Science 2001;292 (5514):7 [PubMed]

2000

• Christoffels V. M., Habets P. E., Das A. T., Clout D. E., van Roon M. A., Moorman A. F., Lamers W. H. A single regulatory module of the carbamoylphosphate synthetase I gene executes its hepatic program of expression Journal of biological chemistry 2000;275 (51):40020-40027 [PubMed]

1999

• Das A. T., Klaver B., Berkhout B. A hairpin structure in the R region of the human immunodeficiency virus type 1 RNA genome is instrumental in polyadenylation site selection Journal of virology 1999;73 (1):81-91 [PubMed]
• Das A. T., Land A., Braakman I., Klaver B., Berkhout B. HIV-1 evolves into a nonsyncytium-inducing virus upon prolonged culture in vitro Virology 1999;263 (1):55-69 [PubMed]
• Klasens B. I., Huthoff H. T., Das A. T., Jeeninga R. E., Berkhout B. The effect of template RNA structure on elongation by HIV-1 reverse transcriptase BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION 1999;1444 (3):355-370 [PubMed]

1998

• Das A. T., van Dam A. P., Klaver B., Berkhout B. Improved envelope function selected by long-term cultivation of a translation-impaired HIV-1 mutant Virology 1998;244 (2):552-562 [PubMed]
• Klasens B. I., Das A. T., Berkhout B. Inhibition of polyadenylation by stable RNA secondary structure Nucleic acids research 1998;26 (8):1870-1876 [PubMed]
• Berkhout B., Das A. T. Similarity of chemokines charge and the V3 domain of HIV-1 env protein Emerging infectious diseases 1998;4 (2):335-336 [PubMed]
• Das A. T., Klaver B., Berkhout B. The 5' and 3' TAR elements of human immunodeficiency virus exert effects at several points in the virus life cycle Journal of virology 1998;72 (11):9217-9223 [PubMed]
• Berkhout B., Das A. T., van Wamel J. L. The native structure of the human immunodeficiency virus type 1 RNA genome is required for the first strand transfer of reverse transcription Virology 1998;249 (2):211-218 [PubMed]

1997

• Das A. T., Klaver B., Klasens B. I., van Wamel J. L., Berkhout B. A conserved hairpin motif in the R-U5 region of the human immunodeficiency virus type 1 RNA genome is essential for replication Journal of virology 1997;71 (3):2346-2356 [PubMed]
• Helou K., Das A. T., Lamers W. H., Hoovers J. M., Szpirer C., Szpirer J., Klinga-Levan K., Levan G. FISH mapping of three ammonia metabolism genes (Glul, Cps1, Glud1) in rat, and the chromosomal localization of GLUL in human and Cps1 in mouse Mammalian genome 1997;8 (5):362-364 [PubMed]
• Berkhout B., Klaver B., Das A. T. Forced evolution of a regulatory RNA helix in the HIV-1 genome Nucleic acids research 1997;25 (5):940-947 [PubMed]
• Das A. T., Klaver B., Berkhout B. Sequence variation of the human immunodeficiency virus primer-binding site suggests the use of an alternative tRNA(Lys) molecule in reverse transcription Journal of general virology 1997;78 (4):837-840 [PubMed]

1996

• Geerts W. J., Verburg M., Jonker A., Das A. T., Boon L., Charles R., Lamers W. H., van Noorden C. J. Gender-dependent regulation of glutamate dehydrogenase expression in periportal and pericentral zones of rat liver lobules journal of histochemistry and cytochemistry 1996;44 (10):1153-1159 [PubMed]
• Oude Essink B. B., Das A. T., Berkhout B. HIV-1 reverse transcriptase discriminates against non-self tRNA primers Journal of molecular biology 1996;264 (2):243-254 [PubMed]
• Das A. T., Salvadó J., Boon L., Biharie G., Moorman A. F., Lamers W. H. Regulation of glutamate dehydrogenase expression in the developing rat liver: control at different levels in the prenatal period European Journal of Biochemistry / FEBS 1996;235 (3):677-682 [PubMed]

1995

• Berkhout B., Klaver B., Das A. T. A conserved hairpin structure predicted for the poly(A) signal of human and simian immunodeficiency viruses Virology 1995;207 (1):276-281 [PubMed]
• Das A. T., Berkhout B. Efficient extension of a misaligned tRNA-primer during replication of the HIV-1 retrovirus Nucleic acids research 1995;23 (8):1319-1326 [PubMed]
• van den Hoff M. J., van de Zande L. P., Dingemanse M. A., Das A. T., Labruyère W., Moorman A. F., Charles R., Lamers W. H. Isolation and characterization of the rat gene for carbamoylphosphate synthetase I European Journal of Biochemistry / FEBS 1995;228 (2):351-361 [PubMed]
• Das A. T., Klaver B., Berkhout B. Reduced replication of human immunodeficiency virus type 1 mutants that use reverse transcription primers other than the natural tRNA(3Lys) Journal of virology 1995;69 (5):3090-3097 [PubMed]
• Oude Essink B. B., Das A. T., Berkhout B. Structural requirements for the binding of tRNA Lys3 to reverse transcriptase of the human immunodeficiency virus type 1 Journal of biological chemistry 1995;270 (40):23867-23874 [PubMed]

1994

• Das A. T., Koken S. E., Essink B. B., van Wamel J. L., Berkhout B. Human immunodeficiency virus uses tRNA(Lys,3) as primer for reverse transcription in HeLa-CD4+ cells FEBS letters 1994;341 (1):49-53 [PubMed]

1993

• Das A. T., Ludérus M. E., Lamers W. H. Identification and analysis of a matrix-attachment region 5' of the rat glutamate-dehydrogenase-encoding gene European Journal of Biochemistry / FEBS 1993;215 (3):777-785 [PubMed]
• Das A. T., Arnberg A. C., Malingré H., Moerer P., Charles R., Moorman A. F., Lamers W. H. Isolation and characterization of the rat gene encoding glutamate dehydrogenase European Journal of Biochemistry / FEBS 1993;211 (3):795-803 [PubMed]

1991

• van den Hoff M. J., Geerts W. J., Das A. T., Moorman A. F., Lamers W. H. cDNA sequence of the long mRNA for human glutamine synthase BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION 1991;1090 (2):249-251 [PubMed]

1990

• Moorman A. F., de Boer P. A., Das A. T., Labruyère W. T., Charles R., Lamers W. H. Expression patterns of mRNAs for ammonia-metabolizing enzymes in the developing rat: the ontogenesis of hepatocyte heterogeneity Histochemical journal 1990;22 (9):457-468 [PubMed]
• van de Zande L., Labruyère W. T., Arnberg A. C., Wilson R. H., van den Bogaert A. J., Das A. T., van Oorschot D. A., Frijters C., Charles R., Moorman A. F. Isolation and characterization of the rat glutamine synthetase-encoding gene Gene 1990;87 (2):225-232 [PubMed]
• Taanman J. W., Schrage C., Ponne N. J., Das A. T., Bolhuis P. A., de Vries H., Agsteribbe E. Isolation of cDNAs encoding subunit VIb of cytochrome c oxidase and steady-state levels of coxVIb mRNA in different tissues Gene 1990;93 (2):285-291 [PubMed]

1989

• Das A. T., Moerer P., Charles R., Moorman A. F., Lamers W. H. Nucleotide sequence of rat liver glutamate dehydrogenase cDNA Nucleic acids research 1989;17 (6):2355 [PubMed]

1988

• Bakker O., Das A. T., AB G. Protein-DNA interactions in vitro with 5'-flanking DNA fragments from the chicken vitellogenin gene Journal of steroid biochemistry 1988;30 (1-6):209-212 [PubMed]