C. van der Werf PhD publications

2020

• Ng Kevin, Titus Erron W., Lieve Krystien V., Roston Thomas M., Mazzanti Andrea, Deiter Frederick H., Denjoy Isabelle, Ingles Jodie, Till Jan, Robyns Tomas, Connors Sean P., Steinberg Christian, Abrams Dominic J., Pang Benjamin, Scheinman Melvin M., Bos J. Martijn, Duffett Stephen A., van der Werf Christian, Maltret Alice, Green Martin S., Rutberg Julie, Balaji Seshadri, Cadrin-Tourigny Julia, Orland Kate M., Knight Linda M., Brateng Caitlin, Wu Jeremy, Tang Anthony S., Skanes Allan C., Manlucu Jaimie, Healey Jeff S., January Craig T., Krahn Andrew D., Collins Kathryn K., Maginot Kathleen R., Fischbach Peter, Etheridge Susan P., Eckhardt Lee L., Hamilton Robert M., Ackerman Michael J., Noguer Ferran Rosés I., Semsarian Christopher, Jura Natalia, Leenhardt Antoine, Gollob Michael H., Priori Silvia G., Sanatani Shubhayan, Wilde Arthur A. M., Deo Rahul C., Roberts Jason D. An International Multicenter Evaluation of Inheritance Patterns, Arrhythmic Risks, and Underlying Mechanisms of CASQ2-Catecholaminergic Polymorphic Ventricular Tachycardia Circulation 2020;142 (10):932-947 [PubMed]
• Wilde A. A. M., Nannenberg E., van der Werf C. Cardiogenetics, 25 years a growing subspecialism Netherlands heart journal 2020;28:39-43 [PubMed]
• Roston Thomas M., van der Werf Christian, Cheung Christopher C., Grewal Jasmine, Davies Brianna, Wilde Arthur A. M., Krahn Andrew D. Caring for the pregnant woman with an inherited arrhythmia syndrome Heart rhythm 2020;17 (2):341–348 [PubMed]
• Lieve Krystien V. V., Dusi Veronica, van der Werf Christian, Bos J. Martijn, Lane Conor M., Stokke Mathis Korseberg, Roston Thomas M., Djupsjöbacka Aurora, Wada Yuko, Denjoy Isabelle, Bundgaard Henning, Noguer Ferran Roses I., Semsarian Christopher, Robyns Tomas, Hofman Nynke, Tanck Michael W., van den Berg Maarten P., Kammeraad Janneke A. E., Krahn Andrew D., Clur Sally-Ann B., Sacher Frederic, Till Jan, Skinner Jonathan R., Tfelt-Hansen Jacob, Probst Vincent, Leenhardt Antoine, Horie Minoru, Swan Heikki, Roberts Jason D., Sanatani Shubhayan, Haugaa Kristina H., Schwartz Peter J., Ackerman Michael J., Wilde Arthur A. M. Heart Rate Recovery After Exercise Is Associated With Arrhythmic Events in Patients With Catecholaminergic Polymorphic Ventricular Tachycardia Circulation. Arrhythmia and electrophysiology 2020;13 (3):e007471 [PubMed]
• Goudswaard Maartje L., Berns Daan, van Kleffens Titia, van den Hondel Karen E., van der Werf Christian, Reijnen Guido, Vis Jeroen, Reijnders Udo J. L., Koppen Hille Medische gevolgen van de inzet van stroomstootwapens Nederlands tijdschrift voor geneeskunde 2020;164 (25)
• Lahrouchi Najim, Raju Hariharan, Lodder Elisabeth M., Papatheodorou Stathis, Miles Chris, Ware James S., Papadakis Michael, Tadros Rafik, Cole Della, Skinner Jonathan R., Crawford Jackie, Love Donald R., Pua Chee J., Soh Bee Y., Bhalshankar Jaydutt D., Govind Risha, Tfelt-Hansen Jacob, Winkel Bo G., van der Werf Christian, Wijeyeratne Yanushi D., Mellor Greg, Till Janice, Cohen Marta, Tome-Esteban Maria, Sharma Sanjay, Wilde Arthur A. M., Cook Stuart A., Sheppard Mary N., Bezzina Connie R., Behr Elijah R. The yield of postmortem genetic testing in sudden death cases with structural findings at autopsy European journal of human genetics 2020;28 (1):17-22 [PubMed]
• van de Poll S. W. E., van der Werf C. Two patients with COVID-19 and a fever-induced Brugada-like electrocardiographic pattern Netherlands heart journal 2020;28 (7-8):431-436 [PubMed]

2019

• Giudicessi John R., Lieve Krystien V. V., Rohatgi Ram K., Koca Faruk, Tester David J., van der Werf Christian, Martijn Bos J., Wilde Arthur A. M., Ackerman Michael J. Assessment and Validation of a Phenotype-Enhanced Variant Classification Framework to Promote or Demote RYR2 Missense Variants of Uncertain Significance Circulation. Genomic and precision medicine 2019;12 (5):e002510 [PubMed]
• van der Werf Christian, Lieve Krystien V, Bos J Martijn, Lane Conor M, Denjoy Isabelle, Roses-Noguer Ferran, Aiba Takeshi, Wada Yuko, Ingles Jodie, Leren Ida S, Rudic Boris, Schwartz Peter J, Maltret Alice, Sacher Frederic, Skinner Jonathan R, Krahn Andrew D, Roston Thomas M, Tfelt-Hansen Jacob, Swan Heikki, Robyns Tomas, Ohno Seiko, Roberts Jason D, van den Berg Maarten P, Kammeraad Janneke A, Probst Vincent, Kannankeril Prince J, Blom Nico A, Behr Elijah R, Borggrefe Martin, Haugaa Kristina H, Semsarian Christopher, Horie Minoru, Shimizu Wataru, Till Janice A, Leenhardt Antoine, Ackerman Michael J, Wilde Arthur A Implantable cardioverter-defibrillators in previously undiagnosed patients with catecholaminergic polymorphic ventricular tachycardia resuscitated from sudden cardiac arrest European heart journal 2019;40 (35):2953-2961 [PubMed]
• Lieve Krystien V.V., Verhagen Judith M.A., Wei Jinhong, Bos J. Martijn, van der Werf Christian, Rosés i Noguer Ferran, Mancini Grazia M.S., Guo Wenting, Wang Ruiwu, van den Heuvel Freek, Frohn-Mulder Ingrid M.E., Shimizu Wataru, Nogami Akihiko, Horigome Hitoshi, Roberts Jason D., Leenhardt Antoine, Crijns Harry J.G., Blank Andreas C., Aiba Takeshi, Wiesfeld Ans C.P., Blom Nico A., Sumitomo Naokata, Till Jan, Ackerman Michael J., Chen S. R.Wayne, van de Laar Ingrid M.B.H., Wilde Arthur A.M. Linking the heart and the brain: Neurodevelopmental disorders in patients with catecholaminergic polymorphic ventricular tachycardia Heart rhythm 2019;16 (2):220-228 [PubMed]
• Raju Hariharan, Ware James S., Skinner Jonathan R., Hedley Paula L., Arno Gavin, Love Donald R., van der Werf Christian, Tfelt-Hansen Jacob, Winkel Bo Gregers, Cohen Marta C., Li Xinzhong, John Shibu, Sharma Sanjay, Jeffery Steve, Wilde Arthur A. M., Christiansen Michael, Sheppard Mary N., Behr Elijah R. Next-generation sequencing using microfluidic PCR enrichment for molecular autopsy BMC cardiovascular disorders 2019;19 (1) [PubMed]
• van der Werf Christian, Wilde Arthur A. M. Why did this patient experience a sudden cardiac arrest? Follow your curiosity! Heart rhythm 2019;16 (8):1240-1241 [PubMed]

2017

• Lieve Krystien V., Verkerk Arie O., Podliesna Svitlana, van der Werf Christian, Tanck Michael W., Hofman Nynke, van Bergen Paul F., Beekman Leander, Bezzina Connie R., Wilde Arthur A. M., Lodder Elisabeth M. Gain-of-function mutation in SCN5A causes ventricular arrhythmias and early onset atrial fibrillation International journal of cardiology 2017;236:187-193 [PubMed]
• Lahrouchi Najim, Raju Hariharan, Lodder Elisabeth M., Papatheodorou Efstathios, Ware James S., Papadakis Michael, Tadros Rafik, Cole Della, Skinner Jonathan R., Crawford Jackie, Love Donald R., Pua Chee J., Soh Bee Y., Bhalshankar Jaydutt D., Govind Risha, Tfelt-Hansen Jacob, Winkel Bo G., van der Werf Christian, Wijeyeratne Yanushi D., Mellor Greg, Till Jan, Cohen Marta C., Tome-Esteban Maria, Sharma Sanjay, Wilde Arthur A. M., Cook Stuart A., Bezzina Connie R., Sheppard Mary N., Behr Elijah R. Utility of Post-Mortem Genetic Testing in Cases of Sudden Arrhythmic Death Syndrome Journal of the American College of Cardiology 2017;69 (17):2134-2145 [PubMed]

2016

• van der Werf Christian, Lieve Krystien V. Beta-blockers in the treatment of catecholaminergic polymorphic ventricular tachycardia Heart rhythm 2016;13 (2):441-442 [PubMed]
• Lieve Krystien V., van der Werf Christian, Wilde Arthur A. Catecholaminergic Polymorphic Ventricular Tachycardia Circulation journal 2016;80 (6):1285-1291 [PubMed]
• van der Werf Christian, Hendrix Anneke, Birnie Erwin, Bots Michiel L., Vink Aryan, Bardai Abdennasser, Blom Marieke T., Bosch Jan, Bruins Wendy, Das C. Kees, Koster Rudolph W., Naujocks Tatjana, Schaap Balthasar, Tan Hanno L., de Vos Ronald, de Vries Philip, Woonink Frits, Doevendans Pieter A., van Weert Henk C., Wilde Arthur A. M., Mosterd Arend, van Langen Irene M. Improving usual care after sudden death in the young with focus on inherited cardiac diseases (the CAREFUL study): a community-based intervention study Europace : European pacing, arrhythmias, and cardiac electrophysiology 2016;18 (4):592-601 [PubMed]
• Lieve Krystien V. V., Wilde Arthur A., van der Werf Christian The Role of Flecainide in the Management of Catecholaminergic Polymorphic Ventricular Tachycardia Arrhythmia & electrophysiology review 2016;5 (1):45-49 [PubMed]

2015

• van der Werf Christian, Wilde Arthur A. M. Catecholaminergic polymorphic ventricular tachycardia: disease with different faces Circulation. Arrhythmia and electrophysiology 2015;8 (3):523-525 [PubMed]
• Chorin Ehud, Havakuk Ofer, Adler Arnon, Steinvil Arie, Rozovski Uri, van der Werf Christian, Postema Pieter G., Topaz Guy, Wilde Arthur A. M., Viskin Sami, Rosso Raphael Diagnostic value of T-wave morphology changes during "QT stretching" in patients with long QT syndrome Heart rhythm 2015;12 (11):2263-2271 [PubMed]
• Lieve Krystien V. V., Wilde Arthur A. M., van der Werf Christian Plotse dood en wegrakingen door een erfelijke hartritmestoornis; mogelijke diagnose bij wegrakingen en plots overlijden van familieleden Nederlands tijdschrift voor geneeskunde 2015;159:A8205 [PubMed]
• Ceelen Manon, van der Werf Christian, Hendrix Anneke, Naujocks Tatjana, Woonink Frits, de Vries Philip, van der Wal Allard, Das Kees Sudden death victims <45 years: Agreement between cause of death established by the forensic physician and autopsy results Journal of forensic and legal medicine 2015;34:62-66 [PubMed]

2014

• van der Werf Christian, Onderwater Astrid T., van Langen Irene M., Smets Ellen M. A. Experiences, considerations and emotions relating to cardiogenetic evaluation in relatives of young sudden cardiac death victims European journal of human genetics 2014;22 (2):192-196 [PubMed]
• van der Werf Christian, Stiekema Lotte, Tan Hanno L., Hofman Nynke, Alders Marielle, van der Wal Allard C., van Langen Irene M., Wilde Arthur A. M. Low rate of cardiac events in first-degree relatives of diagnosis-negative young sudden unexplained death syndrome victims during follow-up Heart rhythm 2014;11 (10):1728-1732 [PubMed]
• Faggioni Michela, van der Werf Christian, Knollmann Bjorn C. Sinus node dysfunction in catecholaminergic polymorphic ventricular tachycardia: risk factor and potential therapeutic target? Trends in cardiovascular medicine 2014;24 (7):273-278 [PubMed]
• van der Werf Christian, Postema Pieter G. Using the electrocardiogram as a crystal ball for cardiovascular and all-cause mortality European heart journal 2014;35 (20):1303-1305 [PubMed]

2013

• Faggioni Michela, Hwang Hyun Seok, van der Werf Christian, Nederend Ineke, Kannankeril Prince J., Wilde Arthur A. M., Knollmann Björn C. Accelerated sinus rhythm prevents catecholaminergic polymorphic ventricular tachycardia in mice and in patients Circulation research 2013;112 (4):689-697 [PubMed]
• van der Werf Christian, Wilde Arthur A. M. Catecholaminergic polymorphic ventricular tachycardia: from bench to bedside Heart (British Cardiac Society) 2013;99 (7):497-504 [PubMed]
• Watanabe Hiroshi, van der Werf Christian, Roses-Noguer Ferran, Adler Arnon, Sumitomo Naokata, Veltmann Christian, Rosso Raphael, Bhuiyan Zahurul A., Bikker Hennie, Kannankeril Prince J., Horie Minoru, Minamino Tohru, Viskin Sami, Knollmann Björn C., Till Jan, Wilde Arthur A. M. Effects of flecainide on exercise-induced ventricular arrhythmias and recurrences in genotype-negative patients with catecholaminergic polymorphic ventricular tachycardia Heart rhythm 2013;10 (4):542-547 [PubMed]
• van der Werf Christian Epidemiology and clinical aspects of sudden cardiac death in the young 2013. 27p. ISBN 9789461822604. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Wilde A. A. M., van Langen I. M.)
• Bakker Roel, van der Werf Christian, van Weert Henk, Das Kees, Dijkstra Geke J., Birnie Erwin, van Langen Irene Erfelijkheidsonderzoek bij plotselinge dood Huisarts en wetenschap 2013;56 (8):370-375
• Nederend Ineke, van der Werf Christian, Wilde Arthur A. M. RyR2 in Cardiac Disordersin: Norbert Weiss, Alexandra Koschak, editors. Pathologies of Calcium Channels. Heidelberg: Springer; 2013. p. 601-614, ISBN 9783642402814
• van der Werf Christian, Wilde Arthur A. M. VTs in Catecholaminergic Cardiomyopathy (Catecholaminergic Polymorphic Ventricular Tachycardia)in: Douglas P. Zipes, José Jalife, editors. Cardiac Electrophysiology: From Cell to Bedside. Philadelphia: Elsevier Saunders; 2013. p. 895-902, ISBN 9781455728565

2012

• van der Werf Christian, Nederend Ineke, Hofman Nynke, van Geloven Nan, Ebink Corné, Frohn-Mulder Ingrid M. E., Alings A. Marco W., Bosker Hans A., Bracke Frank A., van den Heuvel Freek, Waalewijn Reinier A., Bikker Hennie, van Tintelen J. Peter, Bhuiyan Zahurul A., van den Berg Maarten P., Wilde Arthur A. M. Familial Evaluation in Catecholaminergic Polymorphic Ventricular Tachycardia Disease Penetrance and Expression in Cardiac Ryanodine Receptor Mutation-Carrying Relatives Circulation. Arrhythmia and electrophysiology 2012;5 (4):748-756 [PubMed]
• Adler Arnon, van der Werf Christian, Postema Pieter G., Rosso Raphael, Bhuiyan Zahir A., Kalman Jonathan M., Vohra Jitendra K., Guevara-Valdivia Milton E., Marquez Manlio F., Halkin Amir, Benhorin Jesaia, Antzelevitch Charles, Wilde Arthur A. M., Viskin Sami The phenomenon of "QT stunning": The abnormal QT prolongation provoked by standing persists even as the heart rate returns to normal in patients with long QT syndrome Heart rhythm 2012;9 (6):901-908 [PubMed]
• van der Werf Christian, Wilde Arthur A. M. Therapeutic approach for patients with catecholaminergic polymorphic ventricular tachycardia: state of the art and future developments (vol 14, pg 175, 2012) Europace : European pacing, arrhythmias, and cardiac electrophysiology 2012;14 (12):1810
• Wilde Arthur A. M., van der Werf Christian Treatment for patients with catecholaminergic polymorphic ventricular tachycardia: are we in need of randomized trials? Journal of electrocardiology 2012;45 (6):739-740 [PubMed]

2011

• Cox Moniek G. P. J., van der Zwaag Paul A., van der Werf Christian, van der Smagt Jasper J., Noorman Maartje, Bhuiyan Zahir A., Wiesfeld Ans C. P., Volders Paul G. A., van Langen Irene M., Atsma Douwe E., Dooijes Dennis, van den Wijngaard Arthur, Houweling Arjan C., Jongbloed Jan D. H., Jordaens Luc, Cramer Maarten J., Doevendans Pieter A., de Bakker Jacques M. T., Wilde Arthur A. M., van Tintelen J. Peter, Hauer Richard N. W. Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Pathogenic Desmosome Mutations in Index-Patients Predict Outcome of Family Screening: Dutch Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy Genotype-Phenotype Follow-Up Study Circulation 2011;123 (23):2690-U87 [PubMed]
• van der Werf C., Postema P. G. A young man with near-syncope Netherlands heart journal 2011;19 (7-8):361-363 [PubMed]
• van der Werf Christian, Wilde Arthur A. M. Catecholaminergic polymorphic ventricular tachycardiain: H. F. Baars, J. J. van der Smagt, P. A. F. M. Doevendans, editors. Clinical Cardiogenetics. London: Springer-Verlag; 2011. p. 197-206, ISBN 9781849964708
• van der Werf Christian, Wilde Arthur A. M. Catecholaminergic polymorphic ventricular tachycardia: important messages from case reports Europace : European pacing, arrhythmias, and cardiac electrophysiology 2011;13 (1):11-13 [PubMed]
• Sy Raymond W., van der Werf Christian, Chattha Ishvinder S., Chockalingam Priya, Adler Arnon, Healey Jeffrey S., Perrin Mark, Gollob Michael H., Skanes Allan C., Yee Raymond, Gula Lorne J., Leong-Sit Peter, Viskin Sami, Klein George J., Wilde Arthur A., Krahn Andrew D. Derivation and validation of a simple exercise-based algorithm for prediction of genetic testing in relatives of LQTS probands Circulation 2011;124 (20):2187-2194 [PubMed]
• van der Werf Christian, Kannankeril Prince J., Sacher Frederic, Krahn Andrew D., Viskin Sami, Leenhardt Antoine, Shimizu Wataru, Sumitomo Naokata, Fish Frank A., Bhuiyan Zahurul A., Willems Albert R., van der Veen Maurits J., Watanabe Hiroshi, Laborderie Julien, Haïssaguerre Michel, Knollmann Björn C., Wilde Arthur A. M. Flecainide Therapy Reduces Exercise-Induced Ventricular Arrhythmias in Patients With Catecholaminergic Polymorphic Ventricular Tachycardia Journal of the American College of Cardiology 2011;57 (22):2244-2254 [PubMed]
• Postema Pieter G., van der Werf Christian, Wilde Arthur A. M. Idiopathic ventricular fibrillationin: H. F. Baars, J. J. van der Smagt, P. A. F. M. Doevendans, editors. Clinical Cardiogenetics. London: Springer-Verlag; 2011. p. 229-238, ISBN 9781849964708
• Bardai Abdennasser, Berdowski Jocelyn, van der Werf Christian, Blom Marieke T., Ceelen Manon, van Langen Irene M., Tijssen Jan G. P., Wilde Arthur A. M., Koster Rudolph W., Tan Hanno L. Incidence, Causes, and Outcomes of Out-of-Hospital Cardiac Arrest in Children A Comprehensive, Prospective, Population-Based Study in the Netherlands Journal of the American College of Cardiology 2011;57 (18):1822-1828 [PubMed]

2010

• van der Werf Christian, Hofman Nynke, Tan Hanno L., van Dessel Pascal F., Alders Marielle, van der Wal Allard C., van Langen Irene M., Wilde Arthur A. M. Diagnostic yield in sudden unexplained death and aborted cardiac arrest in the young: The experience of a tertiary referral center in The Netherlands Heart rhythm 2010;7 (10):1383-1389 [PubMed]
• Hendrix A., van der Werf C., Bots M. L., Birnie E., van der Smagt J. J., Borleffs C. J. W., Vink A., van Weert H. C., Doevendans P. A. F. M., Wilde A. A. M., Mosterd A., van Langen I. M. Rationale and design of the CAREFUL study : The yield of CARdiogenetic scrEening in First degree relatives of sudden cardiac and UnexpLained death victims <45 years Netherlands heart journal 2010;18 (6):286-290 [PubMed]
• van der Zwaag P. A., Cox M. G. P. J., van der Werf C., Wiesfeld A. C. P., Jongbloed J. D. H., Dooijes D., Bikker H., Jongbloed R., Suurmeijer A. J. H., van den Berg M. P., Hofstra R. M. W., Hauer R. N. W., Wilde A. A. M., van Tintelen J. P. Recurrent and founder mutations in the Netherlands : Plakophilin-2 p.Arg79X mutation causing arrhythmogenic right ventricular cardiomyopathy/dysplasia Netherlands heart journal 2010;18 (12):583-591 [PubMed]
• van der Werf Christian, van Langen Irene M., Wilde Arthur A. M. Sudden Death in the Young What Do We Know About It and How to Prevent? Circulation. Arrhythmia and electrophysiology 2010;3 (1):96-104 [PubMed]

2009

• van der Werf Christian, Oppewal Feike, van der Wal Allard C. De huisarts en obductie Huisarts en wetenschap 2009;52 (3):154
• van der Werf Christian, van Langen Irene M., Wilde Arthur A. M. The Relationship Between Pre-Participation Screening of Young Competitive Athletes and Family Screening Journal of the American College of Cardiology 2009;53 (24):2309-2309; author reply 2310 [PubMed]