D.R. de Waart PhD publications

2021

• Shi Xiaoxia, Aronson Sem J., ten Bloemendaal Lysbeth, Duijst Suzanne, Bakker Robert S., de Waart Dirk R., Bortolussi Giulia, Collaud Fanny, Oude Elferink Ronald P., Muro Andrés F., Mingozzi Federico, Ronzitti Giuseppe, Bosma Piter J. Efficacy of AAV8-hUGT1A1 with Rapamycin in neonatal, suckling, and juvenile rats to model treatment in pediatric CNs patients Molecular therapy. Methods & clinical development 2021;20:287-297

2020

• Smith-Cortinez Natalia, Fagundes Raphael R., Gomez Valentina, Kong Defu, de Waart Dirk R., Heegsma Janette, Sydor Svenja, Olinga Peter, de Meijer Vincent E., Taylor Cormac T., Bank Ruud, Paulusma Coen C., Faber Klaas Nico Collagen release by human hepatic stellate cells requires vitamin C and is efficiently blocked by hydroxylase inhibition FASEB journal 2020 [PubMed]
• Diederen Kay, Li Jia V., Donachie Gillian E., de Meij Tim G., de Waart Dirk R., Hakvoort Theodorus B. M., Kindermann Angelika, Wagner Josef, Auyeung Victoria, te Velde Anje A., Heinsbroek Sigrid E. M., Benninga Marc A., Kinross James, Walker Alan W., de Jonge Wouter J., Seppen Jurgen Exclusive enteral nutrition mediates gut microbial and metabolic changes that are associated with remission in children with Crohn’s disease Scientific reports 2020;10 (1) [PubMed]

2019

• Aronson Sem J., Bakker Robert S., Shi Xiaoxia, Duijst Suzanne, ten Bloemendaal Lysbeth, de Waart Dirk R., Verheij Joanne, Ronzitti Giuseppe, Oude Elferink Ronald P., Beuers Ulrich, Paulusma Coen C., Bosma Piter J. Liver-directed gene therapy results in long-term correction of progressive familial intrahepatic cholestasis type 3 in mice Journal of hepatology 2019;71 (1):153-162 [PubMed]
• Donkers Joanne M., Kooijman Sander, Slijepcevic Davor, Kunst Roni F., Roscam Abbing Reinout L. P., Haazen Lizette, de Waart Dirk R., Levels Johannes H. M., Schoonjans Kristina, Rensen Patrick C. N., Oude Elferink Ronald P. J., van de Graaf Stan F. J. NTCP deficiency in mice protects against obesity and hepatosteatosis JCI insight 2019;4 (14) [PubMed]

2018

• van Golen Rowan F., Olthof Pim B., Lionarons Daniël A., Reiniers Megan J., Alles Lindy K., Uz Zehra, de Haan Lianne, Ergin Bulent, de Waart Dirk R., Maas Adrie, Verheij Joanne, Jansen Peter L., Damink Steven W. Olde, Schaap Frank G., van Gulik Thomas M., Heger Michal FXR agonist obeticholic acid induces liver growth but exacerbates biliary injury in rats with obstructive cholestasis Scientific reports 2018;8 (1):16529 [PubMed]
• van de Wiel Sandra M. W., de Waart D. Rudi, Oude Elferink Ronald P. J., van de Graaf Stan F. J. Intestinal Farnesoid X Receptor Activation by Pharmacologic Inhibition of the Organic Solute Transporter α-β Cellular and molecular gastroenterology and hepatology 2018;5 (3):223-237 [PubMed]
• van Golen Rowan F., Olthof Pim B., de Haan Lianne R., Coelen Robert J., Pechlivanis Alexandros, de Keijzer Mark J., Weijer Ruud, de Waart Dirk R., van Kuilenburg André B. P., Roelofsen Jeroen, Gilijamse Pim W., Maas Martinus A., Lewis Matthew R., Nicholson Jeremy K., Verheij Joanne, Heger Michal The pathophysiology of human obstructive cholestasis is mimicked in cholestatic Gold Syrian hamsters BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 2018;1864 (3):942-951 [PubMed]

2017

• van Dijk Remco, Aronson Sem J., de Waart Dirk R., van de Graaf Stan F., Duijst Suzanne, Seppen Jurgen, Oude Elferink Ronald, Beuers Ulrich, Bosma Piter J. Biliverdin Reductase inhibitors did not improve severe unconjugated hyperbilirubinemia in vivo Scientific reports 2017;7 (1):1646 [PubMed]
• Slijepcevic Davor, Roscam Abbing Reinout L. P., Katafuchi Takeshi, Blank Antje, Donkers Joanne M., van Hoppe Stéphanie, de Waart Dirk R., Tolenaars Dagmar, van der Meer Jonathan H. M., Wildenberg Manon, Beuers Ulrich, Oude Elferink Ronald P. J., Schinkel Alfred H., van de Graaf Stan F. J. Hepatic Uptake of Conjugated Bile Acids Is Mediated by Both Sodium Taurocholate Cotransporting Polypeptide and Organic Anion Transporting Polypeptides and Modulated by Intestinal Sensing of Plasma Bile Acid Levels in Mice Hepatology (Baltimore, Md.) 2017;66 (5):1631-1643 [PubMed]
• Zweers Serge J., de Vries Elisabeth M., Lenicek Martin, Tolenaars Dagmar, de Waart D. Rudi, Koelfat Kiran V. K., Groen Albert K., Olde Damink Steven W. M., Beuers Ulrich, Ponsioen Cyriel, Jansen Peter L. M., Schaap Frank G. Prolonged fibroblast growth factor 19 response in patients with primary sclerosing cholangitis after an oral chenodeoxycholic acid challenge Hepatology international 2017;11 (1):132-140 [PubMed]

2016

• de Waart Dirk R., Naik Jyoti, Utsunomiya Karina S., Duijst Suzanne, Ho-Mok Kam, Bolier A. Ruth, Hiralall Johan, Bull Laura N., Bosma Piter J., Oude Elferink Ronald P. J., Paulusma Coen C. ATP11C targets basolateral bile salt transporter proteins in mouse central hepatocytes Hepatology (Baltimore, Md.) 2016;64 (1):161-174 [PubMed]
• de Oliveira Monique C., Gilglioni Eduardo H., de Boer Bouke A., Runge Jurgen H., de Waart Dirk R., Salgueiro Clairce L., Ishii-Iwamoto Emy L., Oude Elferink Ronald P. J., Gaemers Ingrid C. Bile acid receptor agonists. INT747 and INT777 decrease oestrogen deficiency-related postmenopausal obesity and hepatic steatosis in mice BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 2016;1862 (11):2054-2062 [PubMed]
• Zweers Serge J., Shiryaev Alexey, Komuta Mina, Vesterhus Mette, Hov Johannes R., Perugorria Maria J., de Waart D. Rudi, Chang Jung-Chin, Tol Shanna, te Velde Anje A., de Jonge Wouter J., Banales Jesus M., Roskams Tania, Beuers Ulrich, Karlsen Tom H., Jansen Peter L., Schaap Frank G. Elevated interleukin-8 in bile of patients with primary sclerosing cholangitis Liver international 2016;36 (9):1370-1377 [PubMed]
• Vlahu Carmen A., Aten Jan, de Graaff Marijke, van Veen Henk, Everts Vincent, de Waart Dirk R., Struijk Dirk G., Krediet Raymond T. New Insights into the Effects of Chronic Kidney Failure and Dialysate Exposure on the Peritoneum Peritoneal dialysis international 2016;36 (6):614-622 [PubMed]
• Lionarons Daniël A., Heger Michal, van Golen Rowan F., Alles Lindy K., van der Mark Vincent A., Kloek Jaap J., de Waart Dirk R., Marsman Hendrik A., Rusch Henny, Verheij Joanne, Beuers Ulrich, Paulusma Coen C., van Gulik Thomas M. Simple steatosis sensitizes cholestatic rats to liver injury and dysregulates bile salt synthesis and transport Scientific reports 2016;6:31829 [PubMed]
• Chang Jung-Chin, Go Simei, de Waart Dirk R., Munoz-Garrido Patricia, Beuers Ulrich, Paulusma Coen C., Oude Elferink Ronald Soluble Adenylyl Cyclase Regulates Bile Salt-Induced Apoptosis in Human Cholangiocytes Hepatology (Baltimore, Md.) 2016;64 (2):522-534 [PubMed]

2015

• Naik Jyoti, de Waart Dirk R., Utsunomiya Karina, Duijst Suzanne, Mok Kam Ho, Oude Elferink Ronald P. J., Bosma Piter J., Paulusma Coen C. ATP8B1 and ATP11C: Two Lipid Flippases Important for Hepatocyte Function Digestive diseases (Basel, Switzerland) 2015;33 (3):314-318 [PubMed]
• Slijepcevic Davor, Kaufman Christina, Wichers Catharina G. K., Gilglioni Eduardo H., Lempp Florian A., Duijst Suzanne, de Waart Dirk R., Elferink Ronald P. J. Oude, Mier Walter, Stieger Bruno, Beuers Ulrich, Urban Stephan, van de Graaf Stan F. J. Impaired uptake of conjugated bile acids and hepatitis b virus pres1-binding in na(+) -taurocholate cotransporting polypeptide knockout mice Hepatology (Baltimore, Md.) 2015;62 (1):207-219 [PubMed]
• Barreto Deirisa Lopes, Coester Annemieke M., Heijne Annemiek, de Waart Dirk R., Hoek Frans J., Krediet Raymond T. Soluble VCAM-1 and E-selectin in PD patients: the additive value of the free diffusion coefficient in the assessment of local peritoneal production Peritoneal dialysis international 2015;35 (1):90-93 [PubMed]

2014

• Kunne Cindy, Acco Alexandra, Duijst Suzanne, de Waart Dirk R., Paulusma Coen C., Gaemers Ingrid, Oude Elferink Ronald P. J. FXR-dependent reduction of hepatic steatosis in a bile salt deficient mouse model BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 2014;1842 (5):739-746 [PubMed]
• Kunne Cindy, de Graaff Marijke, Duijst Suzanne, de Waart Dirk R., Oude Elferink Ronald P. J., Paulusma Coen C. Hepatic cytochrome P450 deficiency in mouse models for intrahepatic cholestasis predispose to bile salt-induced cholestasis Laboratory investigation; a journal of technical methods and pathology 2014;94 (10):1103-1113 [PubMed]
• Falix Farah A., Weeda Víola B., Labruyere Wilhelmina T., Poncy Alexis, de Waart Dirk R., Hakvoort Theodorus B. M., Lemaigre Frédéric, Gaemers Ingrid C., Aronson Daniël C., Lamers Wouter H. Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning Developmental biology 2014;396 (2):201-213 [PubMed]
• Montenegro-Miranda P. S., Pichard V., Aubert D., ten Bloemendaal L., Duijst S., de Waart D. R., Ferry N., Bosma P. J. In the rat liver, Adenoviral gene transfer efficiency is comparable to AAV Gene therapy 2014;21 (2):168-174 [PubMed]
• van der Mark Vincent A., de Waart D. Rudi, Ho-Mok Kam S., Tabbers Merit M., Voogt Heleen W., Oude Elferink Ronald P. J., Knisely A. S., Paulusma Coen C. The lipid flippase heterodimer ATP8B1-CDC50A is essential for surface expression of the apical sodium-dependent bile acid transporter (SLC10A2/ASBT) in intestinal Caco-2 cells BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 2014;1842 (12 Part A):2378-2386 [PubMed]

2013

• Montenegro-Miranda Paula S., Pañeda Astrid, ten Bloemendaal Lysbeth, Duijst Suzanne, de Waart Dirk R., Aseguinolaza Gloria Gonzalez, Bosma Piter J. Adeno-associated viral vector serotype 5 poorly transduces liver in rat models PLoS ONE 2013;8 (12):e82597 [PubMed]
• Kunne Cindy, Acco Alexandra, Hohenester Simon, Duijst Suzanne, de Waart Dirk R., Zamanbin Alaleh, Oude Elferink Ronald P. J. Defective bile salt biosynthesis and hydroxylation in mice with reduced cytochrome P450 activity Hepatology (Baltimore, Md.) 2013;57 (4):1509-1517 [PubMed]
• van Dijk Remco, Montenegro-Miranda Paula S., Riviere Christel, Schilderink Ronald, ten Bloemendaal Lysbeth, van Gorp Jacqueline, Duijst Suzanne, de Waart Dirk R., Beuers Ulrich, Haisma Hidde J., Bosma Piter J. Polyinosinic acid blocks adeno-associated virus macrophage endocytosis in vitro and enhances adeno-associated virus liver-directed gene therapy in vivo Human gene therapy 2013;24 (9):807-813 [PubMed]

2012

• van de Steeg Evita, Stránecký Viktor, Hartmannová Hana, Nosková Lenka, Hřebíček Martin, Wagenaar Els, van Esch Anita, de Waart Dirk R., Oude Elferink Ronald P. J., Kenworthy Kathryn E., Sticová Eva, Al-Edreesi Mohammad, Knisely A. S., Kmoch Stanislav, Jirsa Milan, Schinkel Alfred H. Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver Journal of clinical investigation 2012;122 (2):519-528 [PubMed]
• Montenegro-Miranda Paula S., Sneitz Nina, de Waart D. Rudi, ten Bloemendaal Lysbeth, Duijst Suzanne, de Knegt Robert J., Beuers Ulrich, Finel Moshe, Bosma Piter J. Ezetimibe: A biomarker for efficacy of liver directed UGT1A1 gene therapy for inherited hyperbilirubinemia BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 2012;1822 (8):1223-1229 [PubMed]
• de Waart Dirk R., van de Wetering Koen, Kunne Cindy, Duijst Suzanne, Paulusma Coen C., Oude Elferink Ronald P. J. Oral Availability of Cefadroxil Depends on ABCC3 and ABCC4 Drug metabolism and disposition: the biological fate of chemicals 2012;40 (3):515-521 [PubMed]
• Sokolović Aleksandar, Montenegro-Miranda Paula S., de Waart Dirk Rudi, Cappai Radha M. N., Duijst Suzanne, Sokolović Milka, Bosma Piter J. Overexpression of insulin like growth factor binding protein 5 reduces liver fibrosis in chronic cholangiopathy BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 2012;1822 (6):996-1003 [PubMed]
• Vrins Carlos L. J., Ottenhoff Roelof, van den Oever Karin, de Waart Dirk R., Kruyt J. Kar, Zhao Ying, van Berkel Theo J. C., Havekes Louis M., Aerts Johannes M., van Eck Miranda, Rensen Patrick C. N., Groen Albert K. Trans-intestinal cholesterol efflux is not mediated through high density lipoprotein Journal of lipid research 2012;53 (10):2017-2023 [PubMed]

2011

• de Waart Dirk Rudi Basolateral and apical ABC transporters in liver and intestineAmsterdam: Ipskamp; 2011. 200p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Oude Elferink Ronald P. J.; Co-supervisor: Paulusma C. C.)
• Nur Erfan, Verwijs Mirjam, de Waart Dirk R., Schnog John-John B., Otten Hans-Martin, Brandjes Dees P., Biemond Bart J., Elferink Ronald P. J. Oude Increased efflux of oxidized glutathione (GSSG) causes glutathione depletion and potentially diminishes antioxidant defense in sickle erythrocytes BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 2011;1812 (11):1412-1417 [PubMed]
• Montenegro-Miranda Paula, ten Bloemendaal Lysbeth, Kunne Cindy, de Waart Dirk R., Bosma Piter J. Mycophenolate Mofetil Impairs Transduction of Single-Stranded Adeno-Associated Viral Vectors Human gene therapy 2011;22 (5):605-612 [PubMed]
• Lopes Barreto Deirisa, Coester Annemieke M., Noordzij Marlies, Smit Watske, Struijk Dirk G., Rogers Susan, de Waart Dirk R., Krediet Raymond T. Variability of effluent cancer antigen 125 and interleukin-6 determination in peritoneal dialysis patients Nephrology, dialysis, transplantation 2011;26 (11):3739-3744 [PubMed]

2010

• Cruchten S. T. J. van, de Waart D. R., Kunne C., Hooiveld G. J. E. J., Boekschoten M. V., Katan M. B., Elferink R. P. J. Oude, Witkamp R. F. Absorption, distribution, and biliary excretion of cafestol, a potent cholesterol-elevating compound in unfiltered coffees, in mice Drug metabolism and disposition: the biological fate of chemicals 2010;38 (4):635-640 [PubMed]
• Sampimon Denise E., Korte Mario R., Lopes Barreto Deirisa, Vlijm Anniek, de Waart Rudy, Struijk Dirk G., Krediet Raymond T. EARLY DIAGNOSTIC MARKERS FOR ENCAPSULATING PERITONEAL SCLEROSIS: A CASE-CONTROL STUDY Peritoneal dialysis international 2010;30 (2):163-169 [PubMed]
• He Youji, Hakvoort Theodorus B. M., Vermeulen Jacqueline L. M., Labruyère Wilhelmina T., de Waart D. Rudi, van der Hel W. Saskia, Ruijter Jan M., Uylings Harry B. M., Lamers Wouter H. Glutamine Synthetase Deficiency in Murine Astrocytes Results in Neonatal Death Glia 2010;58 (6):741-754 [PubMed]
• He Youji, Hakvoort Theodorus B. M., Köhler S. Eleonore, Vermeulen Jacqueline L. M., de Waart D. Rudi, de Theije Chiel, ten Have Gabrie A. M., van Eijk Hans M. H., Kunne Cindy, Labruyere Wilhelmina T., Houten Sander M., Sokolovic Milka, Ruijter Jan M., Deutz Nicolaas E. P., Lamers Wouter H. Glutamine Synthetase in Muscle Is Required for Glutamine Production during Fasting and Extrahepatic Ammonia Detoxification Journal of biological chemistry 2010;285 (13):9516-9524 [PubMed]
• de Waart Dirk R., Hausler Stephanie, Vlaming Maria L., Kunne Cindy, Hanggi Emanuel, Gruss Hans-Jurgen, Oude Elferink R. P. J., Stieger Bruno Hepatic Transport Mechanisms of Cholyl-L-Lysyl-Fluorescein Journal of pharmacology and experimental therapeutics 2010;334 (1):78-86 [PubMed]
• Vrtovsnik François, Coester Annemieke M., Lopes-Barreto Deirisa, de Waart Dirk R., van der Wal Allard C., Struijk Dirk G., Krediet Raymond T., Zweers Machteld M. Induction of chronic kidney failure in a long-term peritoneal exposure model in the rat: effects on functional and structural peritoneal alterations Peritoneal dialysis international 2010;30 (5):558-569 [PubMed]
• van de Steeg Evita, Wagenaar Els, van der Kruijssen Cornelia M. M., Burggraaff Johanna E. C., de Waart Dirk R., Elferink Ronald P. J. Oude, Kenworthy Kathryn E., Schinkel Alfred H. Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs Journal of clinical investigation 2010;120 (8):2942-2952 [PubMed]
• Markusic David M., de Waart Dirk R., Seppen Jurgen Separating lentiviral vector injection and induction of gene expression in time, does not prevent an immune response to rtTA in rats PLoS ONE 2010;5 (4):e9974 [PubMed]
• de Graaff Marijke, Zegwaard Agnes H., Zweers Machteld M., Vlijm Anniek, de Waart Dirk R., Vandemaele Fréderic, Struijk Dirk G., Krediet Raymond T. THE EFFECTS OF A DIALYSIS SOLUTION WITH A COMBINATION OF GLYCEROL/AMINO ACIDS/DEXTROSE ON THE PERITONEAL MEMBRANE IN CHRONIC RENAL FAILURE Peritoneal dialysis international 2010;30 (2):192-200 [PubMed]

2009

• Paulusma Coen C., Dewaart D. Rudi, Kunne Cindy, Mok Kam S., Oude Elferink Ronald P. J. Activity of the Bile Salt Export Pump (ABCB11) Is Critically Dependent on Canalicular Membrane Cholesterol Content Journal of biological chemistry 2009;284 (15):9947-9954 [PubMed]
• De Waart Dirk R., Oude Elferink Ronald P.J. Bile Canalicular Transportersin: Transporters as Drug Carriers. Wiley-VCH Verlag; 2009. p. 299-324, ISBN 9783527316618
• de Waart Dirk R., Vlaming Maria L. H., Kunne Cindy, Schinkel Alfred H., Oude Elferink Ronald P. J. Complex pharmacokinetic behavior of ezetimibe depends on abcc2, abcc3, and abcg2 Drug metabolism and disposition: the biological fate of chemicals 2009;37 (8):1698-1702 [PubMed]
• Vlaming Maria L. H., Pala Zeliha, van Esch Anita, Wagenaar Els, de Waart Dirk R., van de Wetering Koen, van der Kruijssen Cornelia M. M., Oude Elferink Ronald P. J., van Tellingen Olaf, Schinkel Alfred H. Functionally Overlapping Roles of Abcg2 (Bcrp1) and Abcc2 (Mrp2) in the Elimination of Methotrexate and Its Main Toxic Metabolite 7-Hydroxymethotrexate In vivo Clinical cancer research 2009;15 (9):3084-3093 [PubMed]

2008

• van Westrhenen Roos, Zweers Machteld M., Kunne Cindy, de Waart Dirk R., van der Wal Allard C., Krediet Raymond T. A pyruvate-buffered dialysis fluid induces less peritoneal angiogenesis and fibrosis than a conventional solution Peritoneal dialysis international 2008;28 (5):487-496 [PubMed]
• Paulusma Coen C., Folmer Dineke E., Ho-Mok Kam S., de Waart D. Rudi, Hilarius Petra M., Verhoeven Arthur J., Oude Elferink Ronald P. J. ATP8B1 requires an accessory protein for endoplasmic reticulum exit and plasma membrane lipid flippase activity Hepatology (Baltimore, Md.) 2008;47 (1):268-278 [PubMed]
• Poyck Paul P. C., van Wijk Albert C. W. A., van der Hoeven Tessa V., de Waart Dirk R., Chamuleau Robert A. F. M., van Gulik Thomas M., Oude Elferink Ronald P. J., Hoekstra Ruurdtje Evaluation of a new immortalized human fetal liver cell line (cBAL111) for application in bioartificial liver Journal of hepatology 2008;48 (2):266-275 [PubMed]
• Vlaming Maria L. H., Pala Zeliha, van Esch Anita, Wagenaar Els, van Tellingen Olaf, de Waart Dirk R., Oude Elferink Ronald P. J., van de Wetering Koen, Schinkel Alfred H. Impact of Abcc2 (Mrp2) and Abcc3 (Mrp3) on the In vivo Elimination of Methotrexate and its Main Toxic Metabolite 7-hydroxymethotrexate Clinical cancer research 2008;14 (24):8152-8160 [PubMed]
• Coester A. M., Zweers M. M., de Waart D. R., Krediet R. T. The relationship between effluent potassium due to cellular release, free water transport and CA125 in peritoneal dialysis patients NDT Plus 2008;1 (Suppl. 4):41-45
• Sokolović Milka, Sokolović Aleksandar, Wehkamp Diederik, Ver Loren van Themaat Emiel, de Waart Dirk R., Gilhuijs-Pederson Lisa A., Nikolsky Yuri, van Kampen Antoine H. C., Hakvoort Theodorus B. M., Lamers Wouter H. The transcriptomic signature of fasting murine liver BMC genomics 2008;9 (1):528 [PubMed]

2007

• van Westrhenen Roos, Aten Jan, Hajji Najat, de Boer Onno J., Kunne Cindy, de Waart Dirk R., Krediet Raymond T. Cyclosporin A induces peritoneal fibrosis and angiogenesis during chronic peritoneal exposure to a glucose-based, lactate-buffered dialysis solution in the rat Blood purification 2007;25 (5-6):466-472 [PubMed]
• Vlijm Anniek, de Waart Dirk R., Zweers Machteld M., Krediet Raymond T. Effluent hydroxyproline in experimental peritoneal dialysis Peritoneal dialysis international 2007;27 (2):210-213 [PubMed]
• Coester Annemieke M., Struijk Dirk G., Smit Watske, de Waart Dirk R., Krediet Raymond T. The cellular contribution to effluent potassium and its relation to free water transport during peritoneal dialysis Nephrology, dialysis, transplantation 2007;22 (12):3593-3600 [PubMed]
• Elferink R. P. J. Oude, de Waart R. Transporters in the intestine limiting drug and toxin absorption Journal of physiology and biochemistry 2007;63 (1):75-81 [PubMed]

2006

• Seppen Jurgen, Bakker Conny, de Jong Berry, Kunne Cindy, van den Oever Karin, Vandenberghe Kristin, de Waart Rudi, Twisk Jaap, Bosma Piter Adeno-associated virus vector serotypes mediate sustained correction of bilirubin UDP glucuronosyltransferase deficiency in rats Molecular therapy 2006;13 (6):1085-1092 [PubMed]
• Vlaming M. L. H., Mohrmann K., Wagenaar E., de Waart D. R., Elferink R. P. J. Oude, Lagas J. S., van Tellingen O., Vainchtein L. D., Rosing H., Beijnen J. H., Schellens J. H. M., Schinkel A. H. Carcinogen and anticancer drug transport by Mrp2 in vivo: studies using Mrp2 (Abcc2) knockout mice Journal of pharmacology and experimental therapeutics 2006;318 (1):319-327 [PubMed]
• Zelcer Noam, van de Wetering Koen, de Waart Rudi, Scheffer George L., Marschall Hanns-Ulrich, Wielinga Peter R., Kuil Annemieke, Kunne Cindy, Smith Alexander, van der Valk Martin, Wijnholds Jan, Elferink Ronald Oude, Borst Piet Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides Journal of hepatology 2006;44 (4):768-775 [PubMed]
• de Waart Dirk R., Paulusma Coen C., Kunne Cindy, Oude Elferink Ronald P. J. Multidrug resistance associated protein 2 mediates transport of prostaglandin E2 Liver international 2006;26 (3):362-368 [PubMed]

2005

• Manautou José E., de Waart Dirk R., Kunne Cindy, Zelcer Noam, Goedken Michael, Borst Piet, Elferink Ronald Oude Altered disposition of acetaminophen in mice with a disruption of the Mrp3 gene Hepatology (Baltimore, Md.) 2005;42 (5):1091-1098 [PubMed]
• Hekking Liesbeth H. P., Zweers Machteld M., Keuning Eelco D., Driesprong Bas A. J., de Waart Dirk R., Beelen Robert H. J., van den Born Jacob Apparent successful mesothelial cell transplantation hampered by peritoneal activation Kidney international 2005;68 (5):2362-2367 [PubMed]

2004

• van Westrhenen Roos, de Waart Dirk R., Akman Sema, Krediet Raymond T. Assessment of peritoneal fibrosis by conventional light microscopy and hydroxyproline measurements Peritoneal dialysis international 2004;24 (3):290-292 [PubMed]
• van Esch Sadie, Zweers Machteld M., Jansen Maarten A. M., de Waart Dirk R., van Manen Jeannette G., Krediet Raymond T. Determinants of peritoneal solute transport rates in newly started nondiabetic peritoneal dialysis patients Peritoneal dialysis international 2004;24 (6):554-561 [PubMed]
• Korevaar Johanna C., van Manen Jeannette G., Dekker Friedo W., de Waart Dirk R., Boeschoten Elisabeth W., Krediet Raymond T. Effect of an increase in C-reactive protein level during a hemodialysis session on mortality Journal of the American Society of Nephrology 2004;15 (11):2916-2922 [PubMed]
• Dietrich C. G., Geier A., Wasmuth H. E., Matern S., Gartung C., de Waart D. R., Elferink R. P. J. O. Influence of biliary cirrhosis on the detoxification and elimination of a food derived carcinogen Gut 2004;53 (12):1850-1855 [PubMed]

2003

• Akman Sema, van Westrhenen Roos, de Waart Dirk R., Hiralall Johan K., Zweers Machteld M., Krediet Raymond T. The effect of dwell time on dialysate cancer antigen 125 appearance rates in patients on continuous ambulatory peritoneal dialysis Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 2003;19:24-27 [PubMed]

2002

• Aanen Marissa C., de Waart Dirk R., Williams Paul F., Out Theo A., Zweers Machteld M., Krediet Raymond T. Dextran antibodies in peritoneal dialysis patients treated with icodextrin Peritoneal dialysis international 2002;22 (4):513-515 [PubMed]

2001

• Zweers M. M., Douma C. E., de Waart D. R., Korevaar J. C., Krediet R. T., Struijk D. G. Amphotericin B, mercury chloride and peritoneal transport in rabbits Clinical nephrology 2001;56 (1):60-68 [PubMed]
• van Wijland M. J., de Waart D. R., Groen A. K. Biliary anionic peptide fraction/calcium binding protein inhibits apolipoprotein A-I-mediated cholesterol efflux from cultured cells Biochemical and biophysical research communications 2001;287 (1):1-4 [PubMed]
• Sanusi A. A., Zweers M. M., Weening J. J., de Waart D. R., Struijk D. G., Krediet R. T. Expression of cancer antigen 125 by peritoneal mesothelial cells is not influenced by duration of peritoneal dialysis Peritoneal dialysis international 2001;21 (5):495-500 [PubMed]
• de Waart D. R., Zweers M. M., Struijk D. G., Krediet R. T. Icodextrin degradation products in spent dialysate of CAPD patients and the rat, and its relation with dialysate osmolality Peritoneal dialysis international 2001;21 (3):269-274 [PubMed]
• Dietrich C. G., de Waart D. R., Ottenhoff R., Schoots I. G., Elferink R. P. Increased bioavailability of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in MRP2-deficient rats Molecular pharmacology 2001;59 (5):974-980 [PubMed]
• Dietrich C. G., Ottenhoff R., de Waart D. R., Oude-Elferink R. P. Lack of UGT1 isoforms in Gunn rats changes metabolic ratio and facilitates excretion of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo Toxicology and applied pharmacology 2001;170 (2):137-143 [PubMed]
• Dietrich C. G., de Waart D. R., Ottenhoff R., Bootsma A. H., van Gennip A. H., Elferink R. P. Mrp2-deficiency in the rat impairs biliary and intestinal excretion and influences metabolism and disposition of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo Carcinogenesis 2001;22 (5):805-811 [PubMed]
• Douma C. E., de Waart D. R., Zemel D., Struijk D. G., Krediet R. T. Prostaglandin inhibition by intraperitoneal indomethacin has no effect on peritoneal permeability during stable CAPD Nephrology, dialysis, transplantation 2001;16 (4):803-808 [PubMed]
• Dietrich C. G., Ottenhoff R., de Waart D. R., Oude Elferink R. P. Role of MRP2 and GSH in intrahepatic cycling of toxins Toxicology 2001;167 (1):73-81 [PubMed]

2000

• Smit W., de Waart D. R., Struijk D. G., Krediet R. T. Peritoneal transport characteristics with glycerol-based dialysate in peritoneal dialysis Peritoneal dialysis international 2000;20 (5):557-565 [PubMed]

1999

• Ho-Dac-Pannekeet M. M., Weiss M. F., de Waart D. R., Erhard P., Hiralall J. K., Krediet R. T. Analysis of non enzymatic glycosylation in vivo: impact of different dialysis solutions Peritoneal dialysis international 1999;19 (Suppl. 2):S68-S74 [PubMed]
• Brink M. A., Slors J. F., Keulemans Y. C., Mok K. S., de Waart D. R., Carey M. C., Groen A. K., Tytgat G. N. Enterohepatic cycling of bilirubin: a putative mechanism for pigment gallstone formation in ileal Crohn's disease Gastroenterology 1999;116 (6):1420-1427 [PubMed]
• Zweers M. M., de Waart D. R., Smit W., Struijk D. G., Krediet R. T. Growth factors VEGF and TGF-beta1 in peritoneal dialysis Journal of laboratory and clinical medicine 1999;134 (2):124-132 [PubMed]
• Douma C. E., Zweers M. M., de Waart D. R., van der Wardt A. B., Krediet R. T., Struijk D. G. Substrate and inhibitor for nitric oxide synthase during peritoneal dialysis in rabbits Peritoneal dialysis international 1999;19 (Suppl. 2):S358-S364 [PubMed]
• Zweers M. M., Douma C. E., de Waart D. R., van der Wardt A. B., Ho-Dac-Pannekeet M. M., Krediet R. T., Struijk D. G. The standard peritoneal permeability analysis in the rabbit: a longitudinal model for peritoneal dialysis Peritoneal dialysis international 1999;19 (1):56-64 [PubMed]

1998

• Douma C. E., de Waart D. R., Struijk D. G., Krediet R. T. Are phospholipase A2 and nitric oxide involved in the alterations in peritoneal transport during CAPD peritonitis? Journal of laboratory and clinical medicine 1998;132 (4):329-340 [PubMed]
• Douma C. E., Hiralall J. K., de Waart D. R., Struijk D. G., Krediet R. T. Icodextrin with nitroprusside increases ultrafiltration and peritoneal transport during long CAPD dwells Kidney international 1998;53 (4):1014-1021 [PubMed]

1997

• Douma C. E., de Waart D. R., Struijk D. G., Krediet R. T. The nitric oxide donor nitroprusside intraperitoneally affects peritoneal permeability in CAPD Kidney international 1997;51 (6):1885-1892 [PubMed]

1996

• Douma C. E., de Waart D. R., Struijk D. G., Krediet R. T. Effect of amino acid based dialysate on peritoneal blood flow and permeability in stable CAPD patients: a potential role for nitric oxide? Clinical nephrology 1996;45 (5):295-302 [PubMed]
• Ho-Dac-Pannekeet M. M., Schouten N., Langendijk M. J., Hiralall J. K., de Waart D. R., Struijk D. G., Krediet R. T. Peritoneal transport characteristics with glucose polymer based dialysate Kidney international 1996;50 (3):979-986 [PubMed]

1995

• Douma C. E., de Waart D. R., Zemel D., Imholz A. L., Koomen G. C., Struijk D. G., Krediet R. T. Nitrate in stable CAPD patients and during peritonitis Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 1995;11:36-40 [PubMed]
• Pannekeet M. M., Imholz A. L., Struijk D. G., Koomen G. C., Langedijk M. J., Schouten N., de Waart R., Hiralall J., Krediet R. T. The standard peritoneal permeability analysis: a tool for the assessment of peritoneal permeability characteristics in CAPD patients Kidney international 1995;48 (3):866-875 [PubMed]

1994

• Zemel D., Imholz A. L., de Waart D. R., Dinkla C., Struijk D. G., Krediet R. T. Appearance of tumor necrosis factor-alpha and soluble TNF-receptors I and II in peritoneal effluent of CAPD Kidney international 1994;46 (5):1422-1430 [PubMed]
• de Waart D. R., Koomen G. C., Wanders R. J. Studies on the urinary excretion of thromboxane B2 in Zellweger patients and control subjects: evidence for a major role for peroxisomes in the beta-oxidative chain-shortening of thromboxane B2 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1994;1226 (1):44-48 [PubMed]

1993

• van Acker B. A., Koomen G. C., Koopman M. G., de Waart D. R., Arisz L. Creatinine clearance with cimetidine for measurement of GFR Lancet 1993;341 (8852):1089-1090 [PubMed]

1992

• van Acker B. A., Koomen G. C., Koopman M. G., de Waart D. R., Arisz L. Creatinine clearance during cimetidine administration for measurement of glomerular filtration rate Lancet 1992;340 (8831):1326-1329 [PubMed]