H.P. Kok PhD publications

foto

Publications PhD H.P. Kok

Position
Research Associate
Main activities
Research
Specialisation
Hyperthermia
Focus of research

Petra Kok is responsible for developing the clinical hyperthermia treatment planning at Amsterdam UMC. Her research on hyperthermia has resulted in a research line focusing on clinical hyperthermia treatment planning using on-line adaptive strategies. Furthermore, she explores biological modelling to predict the hyperthermic radiosensitization in terms of effective enhanced radiation dose. Her multidisciplinary research also aims to improve the quality of hyperthermia treatment planning by including patient-specific dielectric tissue properties reconstructed using MR techniques and using advanced thermal modelling techniques including discrete vasculature. Aim of this effort is gaining optimal treatment quality and synergy with radiotherapy and chemotherapy both in terms of tumor temperatures achieved, as well as optimal clinical sequence and time interval with other modalities.

The impact of her research is enhanced by ongoing translation of the developed planning modules into a commercially available clinical hyperthermia treatment planning package for use by clinical hyperthermia professionals worldwide.

Ongoing granted research projects:

  • UVA 2017-10873: Clinical evaluation of the benefit of planning based steering to improve effectiveness of hyperthermia in cervical cancer patients. Project leaders H.P. Kok, J. Crezee, L.J.A. Stalpers. Funding €326.486,-; 1 Postdoc.
  • UVA 2017-10595: Development of treatment planning to optimize clinical effectiveness of hyperthermic intraperitoneal chemotherapy in colorectal cancer patients. Project leaders J. Crezee, N.A.P. Franken, H.P. Kok, P.J. Tanis. Funding € 563.765,-; 2 PhD students

Previous granted research projects:

  • UVA 2012-5540: Towards biological treatment planning in radiotherapy combined with hyperthermia to improve clinical outcome. Project leaders H.P. Kok, N.A.P. Franken, L.J.A. Stalpers. € 553.300,-; 2 PhD students
  • UVA 2012-5393: Active hot spot suppression to improve thermal dose and clinical outcome of locoregional hyperthermia treatment. Project leaders J. Crezee, H.P. Kok, L.J.A. Stalpers.
    € 339.300,-; 1 Postdoc.

Petra Kok has been co-promotor of three PhD students:

  • G. Schooneveldt (UvA, 22 October 2019),
  • C.M. van Leeuwen (UvA, 3 July 2018),
  • A.L. Oei (UvA, 24 March 2017).

Current supervision of PhD students:

  • D.R. Löke (UvA, expected 2021),
  • Two PhD students (vacancies) in the framework of H2020-MSCA-ITN-2020-955625 “HYPERBOOST” (UvA, expected 2024).

Selected other activities:

  • Invited lectures at several conferences and other meetings: MyWave 2020, Lisbon; EuCAP 2020, Copenhagen; PIERS 2019, Rome; STM 2019, St. Pete Beach; Kantonsspital Aarau 2019; San Giovanni Hospital- Oncologic Institute Bellinzona 2017; ESHO 2014, Turin.
  • 2020: Invited guest editor for special issue "Hyperthermia in Cancer" in ‘Cancers’ (impact factor 6.162).
  • Host prof Peter Wust (Berlin), Spinoza chair at University of Amsterdam 3-4 July 2018
  • Regular visits as guest researcher at Chalmers University, Göteborg, Sep 2013 – May 2017.
  • Discussion leader/ opponent during PhD licentiate thesis defense of P. Takook (Gothenburg; 2016 May 18, Towards a microwave hyperthermia system for head and neck tumors)

2021

  • Löke Daan R., Helderman Roxan F. C. P. A., Rodermond Hans M., Tanis Pieter J., Streekstra Geert J., Franken Nicolaas A. P., Oei Arlene L., Crezee Johannes, Kok H. Petra Demonstration of treatment planning software for hyperthermic intraperitoneal chemotherapy in a rat model International journal of hyperthermia 2021;38 (1):38-54 [PubMed]
  • Löke Daan R., Helderman Roxan F. C. P. A., Franken Nicolaas A. P., Oei Arlene L., Tanis Pieter J., Crezee Johannes, Kok H. Petra Simulating drug penetration during hyperthermic intraperitoneal chemotherapy Drug delivery 2021;28 (1):145-161 [PubMed]

2020

  • Gavazzi Soraya, van Lier Astrid L. H. M. W., Zachiu Cornel, Jansen Eric, Lagendijk Jan J. W., Stalpers Lukas J. A., Crezee Hans, Kok H. Petra Advanced patient-specific hyperthermia treatment planning International journal of hyperthermia 2020;37 (1):992-1007 [PubMed]
  • Löke Daan R., Helderman Roxan F. C. P. A., Sijbrands Jan, Rodermond Hans M., Tanis Pieter J., Franken Nicolaas A. P., Oei Arlene L., Kok H. Petra, Crezee Johannes A four-inflow construction to ensure thermal stability and uniformity during hyperthermic intraperitoneal chemotherapy (HIPEC) in rats Cancers 2020;12 (12):1-14 [PubMed]
  • Bakker Akke, Zweije Remko, Kok Henny Petra, Kolff Merel Willemijn, Desiree van den Bongard H. J. G., Schmidt Manfred, van Tienhoven Geertjan, Crezee Hans Clinical feasibility of a high-resolution thermal monitoring sheet for superficial hyperthermia in breast cancer patients Cancers 2020;12 (12):1-18 [PubMed]
  • Crezee Johannes, Zweije Remko, Sijbrands Jan, Kok H. Petra Dedicated 70 MHz RF systems for hyperthermia of challenging tumor locations INTERNATIONAL JOURNAL OF MICROWAVE AND WIRELESS TECHNOLOGIES 2020;12 (9):839-847
  • Gavazzi Soraya, van den Berg Cornelis A. T., Savenije Mark H. F., Kok H. Petra, de Boer Peter, Stalpers Lukas J. A., Lagendijk Jan J. W., Crezee Hans, van Lier Astrid L. H. M. W. Deep learning-based reconstruction of in vivo pelvis conductivity with a 3D patch-based convolutional neural network trained on simulated MR data Magnetic resonance in medicine 2020;84 (5):2772-2787 [PubMed]
  • Schooneveldt Gerben, Löke Daan R., Zweije Remko, Helderman Roxan F. C. P. A., Kok H. Petra, Crezee Hans Experimental validation of a thermophysical fluid model for use in a hyperthermia treatment planning system International journal of heat and mass transfer 2020;152
  • Kok H. Petra, Cressman Erik N. K., Ceelen Wim, Brace Christopher L., Ivkov Robert, Grüll Holger, ter Haar Gail, Wust Peter, Crezee Johannes Heating technology for malignant tumors: a review International journal of hyperthermia 2020;37 (1):711-741 [PubMed]
  • Agnass Pierre, Rodermond Hans M., Zweije Remko, Sijbrands Jan, Vogel Jantien A., van Lienden Krijn P., van Gulik Thomas M., van Veldhuisen Eran, Franken Nicolaas A. P., Oei Arlene L., Kok H. Petra, Besselink Marc G., Crezee Johannes Hycheed system for maintaining stable temperature control during preclinical irreversible electroporation experiments at clinically relevant temperature and pulse settings Sensors (Basel, Switzerland) 2020;20 (21):1-24 [PubMed]
  • Kok H. P., Crezee J. Hyperthermia treatment planning: Clinical application and ongoing researchin: 14th European Conference on Antennas and Propagation, EuCAP 2020. Institute of Electrical and Electronics Engineers Inc.; 2020.
  • Datta Niloy R., Kok H. Petra, Crezee Hans, Gaipl Udo S., Bodis Stephan Integrating Loco-Regional Hyperthermia Into the Current Oncology Practice: SWOT and TOWS Analyses Frontiers in oncology 2020;10 [PubMed]
  • Crezee J., Zweije R., Kok H. P. Loco-regional Hyperthermia Delivery: Patient-specific set-up Procedures for Treatment Optimisationin: 14th European Conference on Antennas and Propagation, EuCAP 2020. Institute of Electrical and Electronics Engineers Inc.; 2020.
  • Kok H. Petra, Beck Marcus, Löke Daan R., Helderman Roxan F. C. P. A., van Tienhoven Geertjan, Ghadjar Pirus, Wust Peter, Crezee Hans Locoregional peritoneal hyperthermia to enhance the effectiveness of chemotherapy in patients with peritoneal carcinomatosis: a simulation study comparing different locoregional heating systems International journal of hyperthermia 2020;37 (1):76-88 [PubMed]
  • Agnass Pierre, van Veldhuisen Eran, van Gemert Martin J. C., van der Geld Cees W. M., van Lienden Krijn P., van Gulik Thomas M., Meijerink Martijn R., Besselink Marc G., Kok H. Petra, Crezee Johannes Mathematical modeling of the thermal effects of irreversible electroporation for in vitro, in vivo, and clinical use: a systematic review International journal of hyperthermia 2020;37 (1):486-505 [PubMed]
  • Petra Kok H., Groen Jort, Bakker Akke, Crezee Johannes Modelling curved contact flexible microstrip applicators for patient-specific superficial hyperthermia treatment planning Cancers 2020;12 (3) [PubMed]
  • Oei A. L., Kok H. P., Oei S. B., Horsman M. R., Stalpers L. J. A., Franken N. A. P., Crezee J. Molecular and biological rationale of hyperthermia as radio- and chemosensitizer Advanced drug delivery reviews 2020;163-164:84-97 [PubMed]
  • Mei Xionge, Cate Rosemarie Ten, van Leeuwen Caspar M., Rodermond Hans M., de Leeuw Lidewij, Dimitrakopoulou Dionysia, Stalpers Lukas J. A., Crezee Johannes, Kok H. Petra, Franken Nicolaas A. P., Oei Arlene L. Radiosensitization by hyperthermia: The effects of temperature, sequence, and time interval in cervical cell lines Cancers 2020;12 (3) [PubMed]
  • Crezee Johannes, Oei Arlene L., Franken Nicolaas A. P., Stalpers Lukas J. A., Kok H. Petra Response: Commentary: The Impact of the Time Interval Between Radiation and Hyperthermia on Clinical Outcome in Patients With Locally Advanced Cervical Cancer Frontiers in oncology 2020;10 [PubMed]
  • Agnass Pierre, van Veldhuisen Eran, Vogel Jantien A, Kok H Petra, de Keijzer Mark J, Schooneveldt Gerben, de Haan Lianne R, Klaessens John H, Scheffer Hester J, Meijerink Martijn R, van Lienden Krijn P, van Gulik Thomas M, Heger Michal, Crezee Johannes, Besselink Marc G Thermodynamic profiling during irreversible electroporation in porcine liver and pancreas: a case study series Journal of clinical and translational research 2020;5 (3):109-132 [PubMed]
  • Helderman Roxan F. C. P. A., Löke Daan R., Verhoeff Jan, Rodermond Hans M., van Bochove Gregor G. W., Boon Menno, van Kesteren Sanne, Garcia Vallejo Juan J., Kok H. Petra, Tanis Pieter J., Franken Nicolaas A. P., Crezee Johannes, Oei Arlene L. The Temperature-Dependent Effectiveness of Platinum-Based Drugs Mitomycin-C and 5-FU during Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Colorectal Cancer Cell Lines Cells 2020;9 (8) [PubMed]
  • Bakker Akke, Zweije Remko, van Tienhoven Geertjan, Kok H. Petra, Sijbrands Jan, van den Bongard H. J. G. Desireé, Rasch Coen R. N., Crezee Hans Two high-resolution thermal monitoring sheets for clinical superficial hyperthermia Physics in medicine and biology 2020;65 (17) [PubMed]

2019

  • Gavazzi Soraya, van den Berg Cornelis A. T., Sbrizzi Alessandro, Kok H. Petra, Stalpers Lukas J. A., Lagendijk Jan J. W., Crezee Hans, van Lier Astrid L. H. M. W. Accuracy and precision of electrical permittivity mapping at 3T: the impact of three B1+ mapping techniques Magnetic resonance in medicine 2019;81 (6):3628-3642 [PubMed]
  • Crezee J., Zweije R., Bakker A., van Tienhoven G., Kok H. P. Combining 70MHz and 434MHz or wIRA Hyperthermia Applicators for Optimal Coverage of Semi-Deep Tumour Sitesin: 2019 49th European Microwave Conference, EuMC 2019. Institute of Electrical and Electronics Engineers Inc.; 2019. p. 164-167
  • Schooneveldt Gerben Computational fluid dynamics powered treatment planning to improve temperature predictions for bladder hyperthermia 2019. 304p. ISBN 9789402817164. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Rasch C. R. N. , de Reijke Theodorus M.; Co-supervisors: Crezee Johannes, Kok H. P.)
  • Kok H. P., Crezee J. Effective electromagnetic coupling and skin cooling during RF heating of pelvic tumoursin: Jan Vrba, Milan Svanda, Ondrej Fiser, David Vrba, editors. Proceedings of European Microwave Conference in Central Europe, EuMCE 2019. Institute of Electrical and Electronics Engineers Inc.; 2019. p. 436-439
  • Oei Arlene L., Korangath Preethi, Mulka Kathleen, Helenius Mikko, Coulter Jonathan B., Stewart Jacqueline, Velarde Esteban, Crezee Johannes, Simons Brian, Stalpers Lukas J. A., Kok H. Petra, Gabrielson Kathleen, Franken Nicolaas A. P., Ivkov Robert Enhancing the abscopal effect of radiation and immune checkpoint inhibitor therapies with magnetic nanoparticle hyperthermia in a model of metastatic breast cancer International journal of hyperthermia 2019;36:47-63 [PubMed]
  • Schooneveldt Gerben, Trefná Hana Dobšíček, Persson Mikael, de Reijke Theo, Blomgren Klas, Kok Petra, Crezee Hans Hyperthermia treatment planning including convective flow in cerebrospinal fluid for brain tumour hyperthermia treatment using a novel dedicated paediatric brain applicator Cancers 2019;11 (8) [PubMed]
  • Dobšíček Trefná H., Schmidt M., van Rhoon G. C., Kok H. P., Gordeyev S. S., Lamprecht U., Marder D., Nadobny J., Ghadjar P., Abdel-Rahman S., Kukiełka A. M., Strnad V., Hurwitz M. D., Vujaskovic Z., Diederich C. J., Stauffer P. R., Crezee J. Quality assurance guidelines for interstitial hyperthermia International journal of hyperthermia 2019;36 (1):277-294 [PubMed]
  • Kok H. Petra, van Dijk Irma W. E. M., Crama Koen F., Franken Nicolaas A. P., Rasch Coen R. N., Merks Johannes H. M., Crezee Johannes, Balgobind Brian V., Bel Arjan Re‑irradiation plus hyperthermia for recurrent pediatric sarcoma; a simulation study to investigate feasibility International journal of oncology 2019;54 (1):209-218 [PubMed]
  • Crezee J., Zweije R., Sijbrands J., Kok H. P. RF and MW systems for hyperthermia of challenging tumour locationsin: Jan Vrba, Milan Svanda, Ondrej Fiser, David Vrba, editors. Proceedings of European Microwave Conference in Central Europe, EuMCE 2019. Institute of Electrical and Electronics Engineers Inc.; 2019. p. 432-435
  • Bakker Akke, van der Zee Jacoba, van Tienhoven Geertjan, Kok H. Petra, Rasch Coen R. N., Crezee Hans Temperature and thermal dose during radiotherapy and hyperthermia for recurrent breast cancer are related to clinical outcome and thermal toxicity: a systematic review International journal of hyperthermia 2019;36 (1):1024-1039 [PubMed]
  • Crezee Hans, Kok H. P., Oei Arlene L., Franken Nicolaas A. P., Stalpers Lukas J. A. The impact of the time interval between radiation and hyperthermia on clinical outcome in patients with locally advanced cervical cancer Frontiers in oncology 2019;9 (MAY) [PubMed]
  • Helderman Roxan F.C.P.A., Löke Daan R., Kok H. Petra, Oei Arlene L., Tanis Pieter J., Franken Nicolaas A.P.Klaas, Crezee Johannes Variation in clinical application of hyperthermic intraperitoneal chemotherapy: A review Cancers 2019;11 (1) [PubMed]

2018

  • Kok H. Petra, Crezee Johannes Adaptive Treatment Planning for Locoregional Hyperthermia: A Necessary Tool for Optimizing Treatment Qualityin: EMF-Med 2018 - 1st EMF-Med World Conference on Biomedical Applications of Electromagnetic Fields and COST EMF-MED Final Event with 6th MCM. Institute of Electrical and Electronics Engineers Inc.; 2018.
  • van Leeuwen Caspar M. Biological modeling of thermoradiotherapy 2018. ISBN 9789402810561. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Rasch C. R. N., Stalpers L. J. A.; Co-supervisors: Crezee J., Kok H. P.)
  • Schooneveldt Gerben, Kok H. Petra, Bakker Akke, Geijsen Elisabeth D., Rasch Coen R. N., de la Rosette Jean J. M. C. H., Hulshof Maarten C. C. M., Reijke Theo M. de, Crezee Hans Clinical validation of a novel thermophysical bladder model designed to improve the accuracy of hyperthermia treatment planning in the pelvic region International journal of hyperthermia 2018;35 (1):383-397 [PubMed]
  • Crezee Johannes, Zweije Remko, Kok H. Petra Design and use of phased array RF systems for loco-regional hyperthermia of deep seated tumorsin: EMF-Med 2018 - 1st EMF-Med World Conference on Biomedical Applications of Electromagnetic Fields and COST EMF-MED Final Event with 6th MCM. Institute of Electrical and Electronics Engineers Inc.; 2018.
  • Ijff Marloes, van Oorschot Bregje, Oei Arlene L., Krawczyk Przemek M., Rodermond Hans M., Stalpers Lukas J. A., Kok H. Petra, Crezee Johannes, Franken Nicolaas A. P. Enhancement of radiation effectiveness in cervical cancer cells by combining ionizing radiation with hyperthermia and molecular targeting agents International journal of molecular sciences 2018;19 (8) [PubMed]
  • Oei Arlene L., Ahire Vidhula R., van Leeuwen C. M., ten Cate Rosemarie, Stalpers Lukas J. A., Crezee Johannes, Kok H. Petra, Franken Nicolaas A. P. Enhancing radiosensitisation of BRCA2-proficient and BRCA2-deficient cell lines with hyperthermia and PARP1-i International journal of hyperthermia 2018;34 (1):39-48 [PubMed]
  • Kok H. P., Korshuize-van Straten L., Bakker A., de Kroon–Oldenhof R., Westerveld G. H., Versteijne E., Stalpers L. J. A., Crezee J. Feasibility of on-line temperature-based hyperthermia treatment planning to improve tumour temperatures during locoregional hyperthermia International journal of hyperthermia 2018;34 (7):1082-1091 [PubMed]
  • Kok H. P., Navarro F., Strigari L., Cavagnaro M., Crezee J. Locoregional hyperthermia of deep-seated tumours applied with capacitive and radiative systems: a simulation study International journal of hyperthermia 2018;34 (6):714-730 [PubMed]
  • van Leeuwen C. M., Oei A. L., ten Cate R., Franken N. A. P., Bel A., Stalpers L. J. A., Crezee J., Kok H. P. Measurement and analysis of the impact of time-interval, temperature and radiation dose on tumour cell survival and its application in thermoradiotherapy plan evaluation International journal of hyperthermia 2018;34 (1):30-38 [PubMed]
  • Kok H. P., Schooneveldt G., Bakker A., de Kroon-Oldenhof R., Korshuize-van Straten L., de Jong C. E., Steggerda-Carvalho E., Geijsen E. D., Stalpers L. J. A., Crezee J. Predictive value of simulated SAR and temperature for changes in measured temperature after phase-amplitude steering during locoregional hyperthermia treatments International journal of hyperthermia 2018;35 (1):330-339 [PubMed]
  • Kok H. P., de Kroon-Oldenhof R., van Straten L. Korshuize, de Jong C. E., Bakker A., Zweije R., Sijbrands J., van Tienhoven G., Crezee J. RF Heating of Pancreatic Tumours Guided by Hyperthermia Treatment Planning and Limited Thermometryin: 2018 48th European Microwave Conference, EuMC 2018. Institute of Electrical and Electronics Engineers Inc.; 2018. p. 332-335
  • Zweije Remko, Kok H. Petra, Bakker Akke, Bel Arjan, Crezee Johannes Technical and Clinical Evaluation of the ALBA-4D 70MHz Loco-Regional Hyperthermia Systemin: 2018 48th European Microwave Conference, EuMC 2018. Institute of Electrical and Electronics Engineers Inc.; 2018. p. 328-331
  • van Leeuwen C. M., Oei A. L., Crezee J., Bel A., Franken N. A. P., Stalpers L. J. A., Kok H. P. The alfa and beta of tumours: A review of parameters of the linear-quadratic model, derived from clinical radiotherapy studies Radiation oncology (London, England) 2018;13 (1) [PubMed]
  • Schooneveldt G., Kok H. P., Bakker A., Geijsen E. D., Hulshof M. C. C. M., Reijke T. M. de, Crezee J. The effect of air pockets in the urinary bladder on the temperature distribution during loco-regional hyperthermia treatment of bladder cancer patients International journal of hyperthermia 2018;35 (1):441-449 [PubMed]
  • van Leeuwen C. M., Crezee J., Oei A. L., Franken N. A. P., Stalpers L. J. A., Bel A., Kok H. P. The effect of time interval between radiotherapy and hyperthermia on planned equivalent radiation dose International journal of hyperthermia 2018;34 (7):901-909 [PubMed]

2017

  • van Leeuwen C. M., Crezee J., Oei A. L., Franken N. A. P., Stalpers L. J. A., Bel A., Kok H. P. 3D radiobiological evaluation of combined radiotherapy and hyperthermia treatments International journal of hyperthermia 2017;33 (2):160-169 [PubMed]
  • Kok H. P., Crezee J. A comparison of the heating characteristics of capacitive and radiative superficial hyperthermia International journal of hyperthermia 2017;33 (4):378-386 [PubMed]
  • van Stam Gerard, Kok H. Petra, Hulshof Maarten C. C. M., Kolff M. Willemijn, van Tienhoven Geertjan, Sijbrands Jan, Bakker Akke, Zum Vörde Sive Vörding Paul J., Oldenborg Sabine, de Greef Martijn, Rasch Coen R. N., Crezee Hans A flexible 70 MHz phase-controlled double waveguide system for hyperthermia treatment of superficial tumours with deep infiltration International journal of hyperthermia 2017;33 (7):796-809 [PubMed]
  • van Leeuwen Caspar M., Oei Arlene L., Chin Kenneth W. T. K., Crezee Johannes, Bel Arjan, Westermann Anneke M., Buist Marrije R., Franken Nicolaas A. P., Stalpers Lukas J. A., Kok H. Petra A short time interval between radiotherapy and hyperthermia reduces in-field recurrence and mortality in women with advanced cervical cancer Radiation oncology (London, England) 2017;12 (1):75 [PubMed]
  • Kok H. P., Van Stam G., Sijbrands J., Bakker A., Kolff M. W., Van Tienhoven G., Hulshof M. C.C.M., Crezee J. Clinical use of a waveguide hyperthermia system for superficial tumors with deep infiltrationin: European Microwave Week 2017. Institute of Electrical and Electronics Engineers Inc.; 2017. p. 868-871
  • Crezee J. , Bennis M. , Gavazzi S. , Stalpers L. J. A., van Lier A. L. H. M. W., Kok H. P. Development of electrical properties tomography for hyperthermia treatment planningin: Microwave Bio Conference (IMBIOC), 2017 First IEEE MTT-S International. IEEE; 2017. p. 112-115, ISBN 9781538617144
  • Oei Arlene L., van Leeuwen Caspar M., Ahire Vidhula R., Rodermond Hans M., ten Cate Rosemarie, Westermann Anneke M., Stalpers Lukas J. A., Crezee Johannes, Kok H. Petra, Krawczyk Przemek M., Kanaar Roland, Franken Nicolaas A. P. Enhancing synthetic lethality of PARP-inhibitor and cisplatin in BRCA-proficient tumour cells with hyperthermia Oncotarget 2017;8 (17):28116-28124 [PubMed]
  • Kok H. Petra, Korshuize-van Straten Linda, Bakker Akke, de Kroon-Oldenhof Rianne, Geijsen Elisabeth D., Stalpers Lukas J. A., Crezee Johannes Online Adaptive Hyperthermia Treatment Planning During Locoregional Heating to Suppress Treatment-Limiting Hot Spots International journal of radiation oncology, biology, physics 2017;99 (4):1039-1047 [PubMed]
  • Kok H. P., Kotte A. N. T. J., Crezee J. Planning, optimisation and evaluation of hyperthermia treatments International journal of hyperthermia 2017;33 (6):593-607 [PubMed]
  • Kok H. P., Crezee J. Progress and future directions in hyperthermia treatment planningin: Microwave Bio Conference (IMBIOC), 2017 First IEEE MTT-S International. IEEE; 2017. p. 116-119, ISBN 9781538617144
  • Oei Arlene L., Vriend Lianne E. M., van Leeuwen Caspar M., Rodermond Hans M., ten Cate Rosemarie, Westermann Anneke M., Stalpers Lukas J. A., Crezee Johannes, Kanaar Roland, Kok H. Petra, Krawczyk Przemek M., Franken Nicolaas A. P. Sensitizing thermochemotherapy with a PARP1-inhibitor Oncotarget 2017;8 (10):16303-16312 [PubMed]
  • Oei Arlene L. Tumor cells can’t stand the heat: Boosting the effectiveness of hyperthermia in cervical carcinoma 2017. 299p. ISBN 9789462955103. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Medema J. P., Stalpers L. J. A.; Co-supervisors: Franken N. A. P., Kok H. P.)

2016

  • Kok H. P., Bakker A., Kolff M. W., Van Tienhoven G., Hulshof M. C.C.M., Van Stam G., Crezee J. A 70 MHz double waveguide set-up for hyperthermia of deep superficial tumorsin: European Microwave Week 2016. Institute of Electrical and Electronics Engineers Inc.; 2016. p. 1219-1222
  • Franken Nicolaas A. P., Kok H. Petra, Crezee Johannes, Barendsen Gerrit W. Analysis of enhancement at small and large radiation doses for effectiveness of inactivation in cultured cells by combining two agents with radiation International journal of radiation biology 2016;92 (9):521-526 [PubMed]
  • Crezee J., van Leeuwen C. M., Oei A. L., van Heerden L. E., Bel A., Stalpers L. J. A., Ghadjar P., Franken N. A. P., Kok H. P. Biological modelling of the radiation dose escalation effect of regional hyperthermia in cervical cancer Radiation oncology (London, England) 2016;11 (1):14 [PubMed]
  • Schooneveldt G., Kok H. P., Balidemaj E., Geijsen E. D., van Ommen F., Sijbrands J., Bakker A., de la Rosette J. J. M. C. H., Hulshof M. C. C. M., de Reijke T. M., Crezee J. Improving hyperthermia treatment planning for the pelvis by accurate fluid modeling Medical physics 2016;43 (10):5442 [PubMed]
  • Schooneveldt Gerben, Bakker Akke, Balidemaj Edmond, Chopra Rajiv, Crezee Johannes, Geijsen Elisabeth D., Hartmann Josefin, Hulshof Maarten C. C. M., Kok H. Petra, Paulides Margarethus M., Sousa-Escandon Alejandro, Stauffer Paul R., Maccarini Paolo F. Thermal dosimetry for bladder hyperthermia treatment. An overview International journal of hyperthermia 2016;32 (4):417-433 [PubMed]
  • Crezee Hans, van Leeuwen Caspar M., Oei Arlene L., Stalpers Lukas J. A., Bel Arjan, Franken Nicolaas A., Kok H. Petra Thermoradiotherapy planning: Integration in routine clinical practice International journal of hyperthermia 2016;32 (1):41-49 [PubMed]

2015

  • Kok H. P., Wust P., Stauffer P. R., Bardati F., van Rhoon G. C., Crezee J. Current state of the art of regional hyperthermia treatment planning: a review Radiation oncology (London, England) 2015;10 (1):196 [PubMed]
  • Oei Arlene L., van Leeuwen Caspar M., ten Cate Rosemarie, Rodermond Hans M., Buist Marrije R., Stalpers Lukas J. A., Crezee Johannes, Kok H. Petra, Medema Jan Paul, Franken Nicolaas A. P. Hyperthermia Selectively Targets Human Papillomavirus in Cervical Tumors via p53-Dependent Apoptosis Cancer research 2015;75 (23):5120-5129 [PubMed]

2014

  • Kok H. Petra, Crezee Johannes, Franken Nicolaas A. P., Stalpers Lukas J. A., Barendsen Gerrit W., Bel Arjan Quantifying the combined effect of radiation therapy and hyperthermia in terms of equivalent dose distributions International journal of radiation oncology, biology, physics 2014;88 (3):739-745 [PubMed]
  • Roelfsema Ferdinand, Pijl Hanno, Kok Petra, Endert Erik, Fliers Eric, Biermasz Nienke R., Pereira Alberto M., Veldhuis Johannes D. Thyrotropin Secretion in Healthy Subjects Is Robust and Independent of Age and Gender, and Only Weakly Dependent on Body Mass Index Journal of clinical endocrinology and metabolism 2014;99 (2):570-578 [PubMed]
  • Kok H. Petra, Ciampa Silvia, de Kroon-Oldenhof Rianne, Steggerda-Carvalho Eva J., van Stam Gerard, Zum Vörde Sive Vörding Paul J., Stalpers Lukas J. A., Geijsen Elisabeth D., Bardati Fernando, Bel Arjan, Crezee Johannes Toward online adaptive hyperthermia treatment planning: correlation between measured and simulated specific absorption rate changes caused by phase steering in patients International journal of radiation oncology, biology, physics 2014;90 (2):438-445 [PubMed]

2013

  • Franken Nicolaas A. P., Oei Arlene L., Kok H. Petra, Rodermond Hans M., Sminia Peter, Crezee Johannes, Stalpers Lukas J. A., Barendsen Gerrit W. Cell survival and radiosensitisation: modulation of the linear and quadratic parameters of the LQ model (Review) International journal of oncology 2013;42 (5):1501-1515 [PubMed]
  • Kok H. P., van den Berg C. A. T., Bel A., Crezee J. Fast thermal simulations and temperature optimization for hyperthermia treatment planning, including realistic 3D vessel networks Medical physics 2013;40 (10):103303 [PubMed]
  • Kok H. Petra, Gellermann Johanna, van den Berg Cornelis A. T., Stauffer Paul R., Hand Jeffrey W., Crezee Johannes Thermal modelling using discrete vasculature for thermal therapy: A review International journal of hyperthermia 2013;29 (4):336-345 [PubMed]

2011

  • de Greef M., Kok H. P., Bel A., Crezee J. 3D versus 2D steering in patient anatomies: A comparison using hyperthermia treatment planning International journal of hyperthermia 2011;27 (1):74-85 [PubMed]
  • Kok H. P., de Greef M., Borsboom P. P., Bel A., Crezee J. Improved power steering with double and triple ring waveguide systems: The impact of the operating frequency International journal of hyperthermia 2011;27 (3):224-239 [PubMed]
  • de Greef M., Kok H. P., Correia D., Borsboom P.-P., Bel A., Crezee J. Uncertainty in hyperthermia treatment planning: the need for robust system design Physics in medicine and biology 2011;56 (11):3233-3250 [PubMed]

2010

  • de Greef M., Kok H. P., Correia D., Bel A., Crezee J. Optimization in hyperthermia treatment planning: the impact of tissue perfusion uncertainty Medical physics 2010;37 (9):4540-4550 [PubMed]
  • Kok H. P., de Greef M., Wiersma J., Bel A., Crezee J. The impact of the waveguide aperture size of the 3D 70 MHz AMC-8 locoregional hyperthermia system on tumour coverage Physics in medicine and biology 2010;55 (17):4899-4916 [PubMed]

2009

  • Kok H. P., de Greef M., Bel A., Crezee J. Acceleration of high resolution temperature based optimization for hyperthermia treatment planning using element grouping Medical physics 2009;36 (8):3795-3805 [PubMed]
  • Correia Davi, Kok H. Petra, de Greef Martijn, Bel Arjan, van Wieringen Niek, Crezee Johannes Body conformal antennas for superficial hyperthermia: the impact of bending contact flexible microstrip applicators on their electromagnetic behavior IEEE transactions on bio-medical engineering 2009;56 (12):2917-2926 [PubMed]
  • Kok H. Petra, de Greef Martijn, Correia Davi, Zum Vorde Sive Vording Paul J., van Stam Gerard, Gelvich Edward A., Bel Arjan, Crezee Johannes FDTD simulations to assess the performance of CFMA-434 applicators for superficial hyperthermia International journal of hyperthermia 2009;25 (6):462-476 [PubMed]
  • Crezee J., van Haaren P. M. A., Westendorp H., de Greef M., Kok H. P., Wiersma J., van Stam G., Sijbrands J., Zum Vörde Sive Vörding P., van Dijk J. D. P., Hulshof M. C. C. M., Bel A. Improving locoregional hyperthermia delivery using the 3-D controlled AMC-8 phased array hyperthermia system: A preclinical study International journal of hyperthermia 2009;25 (7):581-592 [PubMed]
  • Roelfsema Ferdinand, Kok Simon, Kok Petra, Pereira Alberto M., Biermasz Nienke R., Smit Jan W., Frolich Marijke, Keenan Daniel M., Veldhuis Johannes D., Romijn Johannes A. Pituitary-hormone secretion by thyrotropinomas Pituitary 2009;12 (3):200-210 [PubMed]

2008

  • van Haaren P. M. A., Hulshof M. C. C. M., Kok H. P., Oldenborg S., Geijsen E. D., van Lanschot J. J. B., Crezee J. Relation between body size and temperatures during locoregional hyperthermia of oesophageal cancer patients International journal of hyperthermia 2008;24 (8):663-674 [PubMed]

2007

  • Kok H. P., van den Berg C. A. T., van Haaren P. M. A., Crezee J. Artefacts in intracavitary temperature measurements during regional hyperthermia Physics in medicine and biology 2007;52 (17):5157-5171 [PubMed]
  • van Haaren P. M. A., Kok H. P., van den Berg C. A. T., Zum Vorde Sive Vording P. J., Oldenborg S., Stalpers L. J. A., Schilthuis M. S., de Leeuw A. A. C., Crezee J. On verification of hyperthermia treatment planning for cervical carcinoma patients International journal of hyperthermia 2007;23 (3):303-314 [PubMed]
  • Kok H. P., van Haaren P. M. A., van de Kamer J. B., Crezee J. Theoretical comparison of intraluminal heating techniques International journal of hyperthermia 2007;23 (4):395-411 [PubMed]
  • Kok H. P. Treatment planning for locoregional and intraluminal hyperthermia 2007. 189p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Koning Caro C. E.; Co-supervisor: Crezee J.)

2006

  • Kok H. P., van Haaren P. M. A., van de Kamer J. B., Zum Vörde Sive Vörding P. J., Wiersma J., Hulshof M. C. C. M., Geijsen E. D., van Lanschot J. J. B., Crezee J. Prospective treatment planning to improve locoregional hyperthermia for oesophageal cancer International journal of hyperthermia 2006;22 (5):375-389 [PubMed]
  • van Haaren P. M. A., Kok H. P., Zum Vörde Sive Vörding P. J., van Dijk J. D. P., Hulshof M. C. C. M., Fockens P., van Lanschot J. J. B., Crezee J. Reliability of temperature and SAR measurements at oesophageal tumour locations International journal of hyperthermia 2006;22 (7):545-561 [PubMed]
  • van Haaren P. M. A., Kok H. P., Zum Vorde Sive Vording P. J. Reliability of temperature and SAR measurements at oesophageal tumour locations (vol 22, pg 545, 2006) International journal of hyperthermia 2006;22 (8):737

2005

  • Kok H. P., van Haaren P. M. A., van de Kamer J. B., Wiersma J., van Dijk J. D. P., Crezee J. High-resolution temperature-based optimization for hyperthermia treatment planning Physics in medicine and biology 2005;50 (13):3127-3141 [PubMed]
  • Kok H. P., van Haaren P. M. A., van Dijk J. D. P., Crezee J. On estimation of the temperature maximum in intraluminal or intracavitary hyperthermia International journal of hyperthermia 2005;21 (4):287-304 [PubMed]