J. Aten PhD publications

foto

Publications PhD J. Aten

Position
Assistant Professor
Main activities
Education, Research
Specialisation
pathology, immunology
Focus of research
  • Pathobiology of the glomerular visceral epithelial cell in development of nephrotic syndrome.
  • Pathogenesis of renal fibrosis.

2021

  • Wenstedt Eliane F.E., Oppelaar Jetta J., Besseling Stijn, Rorije Nienke M.G., Olde Engberink Rik H.G., Oosterhof Arie, van Kuppevelt Toin H., van den Born Bert Jan H., Aten Jan, Vogt Liffert Distinct osmoregulatory responses to sodium loading in patients with altered glycosaminoglycan structure: a randomized cross-over trial Journal of translational medicine 2021;19 (1) [PubMed]

2020

  • Leandro João, Dodatko Tetyana, Aten Jan, Nemeria Natalia S., Zhang Xu, Jordan Frank, Hendrickson Ronald C., Sanchez Roberto, Yu Chunli, DeVita Robert J., Houten Sander M. DHTKD1 and OGDH display substrate overlap in cultured cells and form a hybrid 2-oxo acid dehydrogenase complex in vivo Human molecular genetics 2020;29 (7):1168-1179 [PubMed]
  • Wenstedt Eliane F. E., Engberink Rik H. G. Olde, Rorije Nienke M. G., van den Born Bert-Jan H., Claessen Nike, Aten Jan, Vogt Liffert Salt-sensitive blood pressure rise in type 1 diabetes patients is accompanied by disturbed skin macrophage influx and lymphatic dilation—a proof-of-concept study Translational research 2020;217:23-32 [PubMed]

2019

  • Kinashi Hiroshi, Toda Naohiro, Sun Ting, Nguyen Tri Q., Suzuki Yasuhiro, Katsuno Takayuki, Yokoi Hideki, Aten Jan, Mizuno Masashi, Maruyama Shoichi, Yanagita Motoko, Goldschmeding Roel, Ito Yasuhiko Connective tissue growth factor is correlated with peritoneal lymphangiogenesis Scientific reports 2019;9 (1) [PubMed]
  • Wenstedt Eliane F. E., Verberk Sanne G. S., Kroon Jeffrey, Neele Annette E., Baardman Jeroen, Claessen Nike, Pasaoglu Ozge T., Rademaker Emma, Schrooten Esmee M., Wouda Rosa D., de Winther Menno P. J., Aten Jan, Vogt Liffert, van den Bossche Jan Salt increases monocyte CCR2 expression and inflammatory responses in humans JCI insight 2019;4 (21) [PubMed]

2018

  • Rampanelli Elena, Ochodnicky Peter, Vissers Johannes P. C., Butter Loes M., Claessen Nike, Calcagni Alessia, Kors Lotte, Gethings Lee A., Bakker Stephan J. L., de Borst Martin H., Navis Gerjan J., Liebisch Gerhard, Speijer Dave, van den Bergh Weerman Marius A., Jung Bettina, Aten Jan, Steenbergen Eric, Schmitz Gerd, Ballabio Andrea, Florquin Sandrine, Aerts Johannes M. FG, Leemans Jaklien C. Excessive dietary lipid intake provokes an acquired form of lysosomal lipid storage disease in the kidney Journal of pathology 2018;246 (4):470-484 [PubMed]

2017

  • Kinashi Hiroshi, Falke Lucas L., Nguyen Tri Q., Bovenschen Niels, Aten Jan, Leask Andrew, Ito Yasuhiko, Goldschmeding Roel Connective tissue growth factor regulates fibrosis-associated renal lymphangiogenesis Kidney international 2017;92 (4):850-863 [PubMed]

2016

  • Tol Marc J., Ottenhoff Roelof, van Eijk Marco, Zelcer Noam, Aten Jan, Houten Sander M., Geerts Dirk, van Roomen Cindy, Bierlaagh Marlou C., Scheij Saskia, Hoeksema Marten A., Aerts Johannes M., Bogan Jonathan S., Dorn Gerald W., Argmann Carmen A., Verhoeven Arthur J. A PPARγ-Bnip3 Axis Couples Adipose Mitochondrial Fusion-Fission Balance to Systemic Insulin Sensitivity Diabetes 2016;65 (9):2591-2605 [PubMed]
  • Marques André R. A., Gabriel Tanit L., Aten Jan, van Roomen Cindy P. A. A., Ottenhoff Roelof, Claessen Nike, Alfonso Pilar, Irún Pilar, Giraldo Pilar, Aerts Johannes M. F. G., van Eijk Marco Gpnmb Is a Potential Marker for the Visceral Pathology in Niemann-Pick Type C Disease PLoS ONE 2016;11 (1):e0147208 [PubMed]
  • Vlahu Carmen A., Aten Jan, de Graaff Marijke, van Veen Henk, Everts Vincent, de Waart Dirk R., Struijk Dirk G., Krediet Raymond T. New Insights into the Effects of Chronic Kidney Failure and Dialysate Exposure on the Peritoneum Peritoneal dialysis international 2016;36 (6):614-622 [PubMed]

2015

  • Gerritsen Karin G. F., Leeuwis Jan Willem, Koeners Maarten P., Bakker Stephan J. L., van Oeveren Willem, Aten Jan, Tarnow Lise, Rossing Peter, Wetzels Jack F. M., Joles Jaap A., Kok Robbert Jan, Goldschmeding Roel, Nguyen Tri Q. Elevated Urinary Connective Tissue Growth Factor in Diabetic Nephropathy Is Caused by Local Production and Tubular Dysfunction Journal of diabetes research 2015;2015:539787 [PubMed]
  • Jebbink J. M., Boot R. G., Keijser R., Moerland P. D., Aten J., Veenboer G. J. M., van Wely M., Buimer M., Ver Loren van Themaat E., Aerts J. M. F. G., van der Post J. A. M., Afink G. B., Ris-Stalpers C. Increased glucocerebrosidase expression and activity in preeclamptic placenta Placenta 2015;36 (2):160-169 [PubMed]
  • Vlahu Carmen A., de Graaff Marijke, Aten Jan, Struijk Dirk G., Krediet Raymond T. Lymphangiogenesis and Lymphatic Absorption Are Related and Increased in Chronic Kidney Failure, Independent of Exposure to Dialysis Solutions Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 2015;31:21-25 [PubMed]
  • Marques André R. A., Aten Jan, Ottenhoff Roelof, van Roomen Cindy P. A. A., Herrera Moro Daniela, Claessen Nike, Vinueza Veloz María Fernanda, Zhou Kuikui, Lin Zhanmin, Mirzaian Mina, Boot Rolf G., de Zeeuw Chris I., Overkleeft Herman S., Yildiz Yildiz, Aerts Johannes M. F. G. Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice PLoS ONE 2015;10 (8):e0135889 [PubMed]
  • Arai Haruna, Hayashi Hiroki, Takahashi Kazuo, Koide Shigehisa, Sato Waichi, Hasegawa Midori, Yamaguchi Yutaka, Aten Jan, Ito Yasuhiko, Yuzawa Yukio Tubulointerstitial fibrosis in patients with IgG4-related kidney disease: pathological findings on repeat renal biopsy Rheumatology international 2015;35 (6):1093-1101 [PubMed]
  • Herrera Moro Chao Daniela, Kallemeijn Wouter W., Marques Andre R. A., Orre Marie, Ottenhoff Roelof, van Roomen Cindy, Foppen Ewout, Renner Maria C., Moeton Martina, van Eijk Marco, Boot Rolf G., Kamphuis Willem, Hol Elly M., Aten Jan, Overkleeft Hermen S., Kalsbeek Andries, Aerts Johannes M. F. G. Visualization of Active Glucocerebrosidase in Rodent Brain with High Spatial Resolution following In Situ Labeling with Fluorescent Activity Based Probes PLoS ONE 2015;10 (9):e0138107 [PubMed]

2014

  • Gaspar Paulo, Kallemeijn Wouter W., Strijland Anneke, Scheij Saskia, van Eijk Marco, Aten Jan, Overkleeft Herman S., Balreira Andrea, Zunke Friederike, Schwake Michael, Sá Miranda Clara, Aerts Johannes M. F. G. Action myoclonus-renal failure syndrome: diagnostic applications of activity-based probes and lipid analysis Journal of lipid research 2014;55 (1):138-145 [PubMed]
  • van Weeghel Michel, Ofman Rob, Argmann Carmen A., Ruiter Jos P. N., Claessen Nike, Oussoren Saskia V., Wanders Ronald J. A., Aten Jan, Houten Sander M. Identification and characterization of Eci3, a murine kidney-specific Δ3,Δ2-enoyl-CoA isomerase FASEB journal 2014;28 (3):1365-1374 [PubMed]
  • Gabriel Tanit L., Tol Marc J., Ottenhof Roelof, van Roomen Cindy, Aten Jan, Claessen Nike, Hooibrink Berend, de Weijer Barbara, Serlie Mireille J., Argmann Carmen, van Elsenburg Leonie, Aerts Johannes M. F. G., van Eijk Marco Lysosomal stress in obese adipose tissue macrophages contributes to MITF-dependent Gpnmb induction Diabetes 2014;63 (10):3310-3323 [PubMed]
  • Bakker Pieter J., Butter Loes M., Kors Lotte, Teske Gwendoline J. D., Aten Jan, Sutterwala Fayyaz S., Florquin Sandrine, Leemans Jaklien C. Nlrp3 is a key modulator of diet-induced nephropathy and renal cholesterol accumulation Kidney international 2014;85 (5):1112-1122 [PubMed]

2013

  • Sokolović Aleksandar, van Roomen Cindy P. A. A., Ottenhoff Roelof, Scheij Saskia, Hiralall Johan K., Claessen Nike, Aten Jan, Oude Elferink Ronald P. J., Groen Albert K., Sokolović Milka Fasting reduces liver fibrosis in a mouse model for chronic cholangiopathies BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 2013;1832 (10):1482-1491 [PubMed]

2012

  • Sachs Norman, Claessen Nike, Aten Jan, Kreft Maaike, Teske Gwendoline J. D., Koeman Anneke, Zuurbier Coert J., Janssen Hans, Sonnenberg Arnoud Blood pressure influences end-stage renal disease of Cd151 knockout mice Journal of clinical investigation 2012;122 (1):348-358 [PubMed]
  • van Maldegem F., Wormhoudt T. A. M., Mulder M. M. S., Oud M. E. C. M., Schilder-Tol E., Musler A. R., Aten J., Saeed P., Kersten M. J., Pals S. T., van Noesel C. J. M., Bende R. J. Chlamydia psittaci-negative ocular adnexal marginal zone B-cell lymphomas have biased V(H)4-34 immunoglobulin gene expression and proliferate in a distinct inflammatory environment Leukemia 2012;26 (7):1647-1653 [PubMed]
  • Lombardo Elisa, van Roomen Cindy P. A. A., van Puijvelde Gijs H., Ottenhoff Roelof, van Eijk Marco, Aten Jan, Kuiper Johan, Overkleeft Herman S., Groen Albert K., Verhoeven Arthur J., Aerts Johannes M. F. G., Bietrix Florence Correction of Liver Steatosis by a Hydrophobic Iminosugar Modulating Glycosphingolipids Metabolism PLoS ONE 2012;7 (10):e38520-(10 p.) [PubMed]
  • Kallemeijn Wouter W., Li Kah-Yee, Witte Martin D., Marques André R. A., Aten Jan, Scheij Saskia, Jiang Jianbing, Willems Lianne I., Voorn-Brouwer Tineke M., van Roomen Cindy P. A. A., Ottenhoff Roelof, Boot Rolf G., van den Elst Hans, Walvoort Marthe T. C., Florea Bogdan I., Codée Jeroen D. C., van der Marel Gijsbert A., Aerts Johannes M. F. G., Overkleeft Herman S. Novel Activity-Based Probes for Broad-Spectrum Profiling of Retaining beta-Exoglucosidases In Situ and In Vivo Angewandte Chemie (International ed. in English) 2012;51 (50):12529-12533 [PubMed]
  • Rops Angelique L. W. M. M., van den Hoven Mabel J., Veldman Bart A., Salemink Simone, Vervoort Gerald, Elving Lammy D., Aten Jan, Wetzels Jack F., van der Vlag Johan, Berden Jo H. M. Urinary heparanase activity in patients with Type 1 and Type 2 diabetes Nephrology, dialysis, transplantation 2012;27 (7):2853-2861 [PubMed]

2011

  • Ito Yasuhiko Connective tissue growth factor in renal development and injury 2011. 227p. ISBN 9789090262949. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Matsuo S., Weening J. J.; Co-supervisors: Goldschmeding R., Aten J.)
  • Bakermans Adrianus J., Geraedts Tom R., van Weeghel Michel, Denis Simone, João Ferraz Maria, Aerts Johannes M. F. G., Aten Jan, Nicolay Klaas, Houten Sander M., Prompers Jeanine J. Fasting-induced myocardial lipid accumulation in long-chain acyl-CoA dehydrogenase knockout mice is accompanied by impaired left ventricular function Circulation. Cardiovascular imaging 2011;4 (5):558-565 [PubMed]
  • Aerts Johannes M., Boot Rolf G., van Eijk Marco, Groener Johanna, Bijl Nora, Lombardo Elisa, Bietrix Florence M., Dekker Nick, Groen Albert K., Ottenhoff Roelof, van Roomen Cindy, Aten Jan, Serlie Mireille, Langeveld Mirjam, Wennekes Tom, Overkleeft Hermen S. Glycosphingolipids and insulin resistance Advances in experimental medicine and biology 2011;721:99-119 [PubMed]
  • Ito Yasuhiko, Aten Jan, Nguyen Tri Q., Joles Jaap A., Matsuo Seiichi, Weening Jan J., Goldschmeding Roel Involvement of Connective Tissue Growth Factor in Human and Experimental Hypertensive Nephrosclerosis Nephron. Experimental nephrology 2011;117 (1):e9-e20 [PubMed]
  • Reuwer Anne, van Eijk Marco, Houttuijn-Bloemendaal Felicia, van der Loos Chris, Claessen Nike, Teeling Peter, Kastelein J. J., Hamann Jörg, Goffin Vincent, von der Thüsen Jan, Twickler Marcel, Aten Jan The prolactin receptor is expressed in macrophages within human carotid atherosclerotic plaques: a role for prolactin in atherogenesis? Journal of endocrinology 2011;208 (2):107-117 [PubMed]

2010

  • Kroening Sven, Neubauer Emily, Wullich Bernd, Aten Jan, Goppelt-Struebe Margarete Characterization of connective tissue growth factor expression in primary cultures of human tubular epithelial cells: modulation by hypoxia American journal of physiology. Renal physiology 2010;298 (3):F796-F806 [PubMed]
  • Mizutani Makoto, Ito Yasuhiko, Mizuno Masashi, Nishimura Hayato, Suzuki Yasuhiro, Hattori Ryohei, Matsukawa Yoshihisa, Imai Masaki, Oliver Noelynn, Goldschmeding Roel, Aten Jan, Krediet Raymond T., Yuzawa Yukio, Matsuo Seiichi Connective tissue growth factor (CTGF/CCN2) is increased in peritoneal dialysis patients with high peritoneal solute transport rate American journal of physiology. Renal physiology 2010;298 (3):F721-F733 [PubMed]
  • de Boer Onno J., van der Meer Jelger J., Teeling Peter, van der Loos Chris M., Idu Mirza M., van Maldegem Febe, Aten Jan, van der Wal Allard C. Differential expression of interleukin-17 family cytokines in intact and complicated human atherosclerotic plaques Journal of pathology 2010;220 (4):499-508 [PubMed]
  • Ito Yasuhiko, Goldschmeding Roel, Kasuga Hirotake, Claessen Nike, Nakayama Masahiro, Yuzawa Yukio, Sawai Akiho, Matsuo Seiichi, Weening Jan J., Aten Jan Expression patterns of connective tissue growth factor and of TGF-beta isoforms during glomerular injury recapitulate glomerulogenesis American journal of physiology. Renal physiology 2010;299 (3):F545-F558 [PubMed]
  • Aerts J. M., Boot R. G., van Eijk M., Groener J., Bijl N., Lombardo E., Bietrix F. M., Dekker N. [=Nick], Groen A. K., Ottenhoff R., van Roomen C., Aten J., Serlie M., Langeveld M., Wennekes T., Overkleeft H. S. Glycosphingolipids and insulin resistancein: A. Cowart, editors. Sphingolipids and Metabolic Disease. S.l.: Landes Bioscience and Springer Science; 2010. p. 20-41, ISBN 9781461406501
  • Witte Martin D., Kallemeijn Wouter W., Aten Jan, Li Kah-Yee, Strijland Anneke, Donker-Koopman Wilma E., van den Nieuwendijk Adrianus M. C. H., Bleijlevens Boris, Kramer Gertjan, Florea Bogdan I., Hooibrink Berend, Hollak Carla E. M., Ottenhoff Roelof, Boot Rolf G., van der Marel Gijsbert A., Overkleeft Herman S., Aerts Johannes M. F. G. Ultrasensitive in situ visualization of active glucocerebrosidase molecules Nature chemical biology 2010;6 (12):907-913 [PubMed]

2009

  • Bijl Nora, Sokolović Milka, Vrins Carlos, Langeveld Mirjam, Moerland Perry D., Ottenhoff Roelof, van Roomen Cindy P. A. A., Claessen Nike, Boot Rolf G., Aten Jan, Groen Albert K., Aerts Johannes M. F. G., van Eijk Marco Modulation of Glycosphingolipid Metabolism Significantly Improves Hepatic Insulin Sensitivity and Reverses Hepatic Steatosis in Mice Hepatology (Baltimore, Md.) 2009;50 (5):1431-1441 [PubMed]
  • van Eijk Marco, Aten Jan, Bijl Nora, Ottenhoff Roelof, van Roomen Cindy P. A. A., Dubbelhuis Peter F., Seeman Ingar, Ghauharali-van der Vlugt Karen, Overkleeft Hermen S., Arbeeny Cynthia, Groen Albert K., Aerts Johannes M. F. G. Reducing Glycosphingolipid Content in Adipose Tissue of Obese Mice Restores Insulin Sensitivity, Adipogenesis and Reduces Inflammation PLoS ONE 2009;4 (3):e4723 [PubMed]

2008

  • Nguyen Tri Q., Roestenberg Peggy, van Nieuwenhoven Frans A., Bovenschen Niels, Li Zeke, Xu Leon, Oliver Noelynn, Aten Jan, Joles Jaap A., Vial Cecilia, Brandan Enrique, Lyons Karen M., Goldschmeding Roel CTGF Inhibits BMP-7 Signaling in Diabetic Nephropathy Journal of the American Society of Nephrology 2008;19 (11):2098-2107 [PubMed]

2007

  • van Westrhenen Roos, Aten Jan, Hajji Najat, de Boer Onno J., Kunne Cindy, de Waart Dirk R., Krediet Raymond T. Cyclosporin A induces peritoneal fibrosis and angiogenesis during chronic peritoneal exposure to a glucose-based, lactate-buffered dialysis solution in the rat Blood purification 2007;25 (5-6):466-472 [PubMed]
  • Aerts Johannes M., Ottenhoff Roelof, Powlson Andrew S., Grefhorst Aldo, van Eijk Marco, Dubbelhuis Peter F., Aten Jan, Kuipers Folkert, Serlie Mireille J., Wennekes Tom, Sethi Jaswinder K., O'Rahilly Stephen, Overkleeft Hermen S. Pharmacological inhibition of glucosylceramide synthase enhances insulin sensitivity Diabetes 2007;56 (5):1341-1349 [PubMed]
  • Celie Johanna W. A. M., Rutjes Niels W. P., Keuning Eelco D., Soininen Raija, Heljasvaara Ritva, Pihlajaniemi Taina, Dräger Angelika M., Zweegman Sonja, Kessler Floortje L., Beelen Robert H. J., Florquin Sandrine, Aten Jan, van den Born Jacob Subendothelial heparan sulfate proteoglycans become major L-selectin and monocyte chemoattractant protein-1 ligands upon renal ischemia/reperfusion American journal of pathology 2007;170 (6):1865-1878 [PubMed]

2006

  • Smeets Bart, Steenbergen Mark L. M., Dijkman Henry B. P. M., Verrijp Kiek N., te Loeke Nathalie A. J. M., Aten Jan, Steenbergen Eric J., Wetzels Jack F. M. Angiotensin converting enzyme inhibition prevents development of collapsing focal segmental glomerulosclerosis in Thy-1.1 transgenic mice Nephrology, dialysis, transplantation 2006;21 (11):3087-3097 [PubMed]
  • van den Hoven M. J., Rops A. L., Bakker M. A., Aten J., Rutjes N., Roestenberg P., Goldschmeding R., Zcharia E., Vlodavsky I., van der Vlag J., Berden J. H. Increased expression of heparanase in overt diabetic nephropathy Kidney international 2006;70 (12):2100-2108 [PubMed]
  • Roestenberg Peggy, van Nieuwenhoven Frans A., Joles Jaap A., Trischberger Claudia, Martens Paula P., Oliver Noelynn, Aten Jan, Höppener Jo W., Goldschmeding Roel Temporal expression profile and distribution pattern indicate a role of connective tissue growth factor (CTGF/CCN-2) in diabetic nephropathy in mice American journal of physiology. Renal physiology 2006;290 (6):F1344-F1354 [PubMed]

2005

  • van Westrhenen Roos, Aten Jan, Aberra Medhanit, Dragt Cindy A. M., Deira Gregory, Krediet Raymond T. Effects of inhibition of the polyol pathway during chronic peritoneal exposure to a dialysis solution Peritoneal dialysis international 2005;25 (Suppl. 3):S18-S21 [PubMed]
  • Nauta Alma J., de Haij Simone, Bottazzi Barbara, Mantovani Alberto, Borrias Maria C., Aten Jan, Rastaldi Maria Pia, Daha Mohamed R., van Kooten Cees, Roos Anja Human renal epithelial cells produce the long pentraxin PTX3 Kidney international 2005;67 (2):543-553 [PubMed]
  • Brinkman J., Wijburg F. A., Hollak C. E., Groener J. E., Verhoek M., Scheij S., Aten J., Boot R. G., Aerts J. M. Plasma chitotriosidase and CCL18: Early biochemical surrogate markers in type B Niemann-Pick disease Journal of inherited metabolic disease 2005;28 (1):13-20 [PubMed]

2004

  • Rouschop Kasper M. A., Sewnath Miguel E., Claessen Nike, Roelofs Joris J. T. H., Hoedemaeker Inge, van der Neut Ronald, Aten Jan, Pals Steven T., Weening Jan J., Florquin Sandrine CD44 deficiency increases tubular damage but reduces renal fibrosis in obstructive nephropathy Journal of the American Society of Nephrology 2004;15 (3):674-686 [PubMed]
  • van der Straaten Hanneke M., Canninga-van Dijk Marijke R., Verdonck Leo F., Castigliego Domenico, Borst H. P. Eric, Aten Jan, Fijnheer Rob Extra-domain-A fibronectin: a new marker of fibrosis in cutaneous graft-versus-host disease Journal of investigative dermatology 2004;123 (6):1057-1062 [PubMed]
  • van den Berg J. G. Immune-mediated podocyte injury and the idiopathic nephrotic syndrome 2004. 97p. ISBN 9789090185248. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Weening J. J.; Co-supervisor: Aten J.)
  • Kanemoto Katsuyoshi, Usui Joichi, Nitta Kosaku, Horita Shigeru, Harada Atsumi, Koyama Akio, Aten Jan, Nagata Michio In situ expression of connective tissue growth factor in human crescentic glomerulonephritis Virchows Archiv 2004;444 (3):257-263 [PubMed]

2003

  • Lam Suzanne, van der Geest Reinier N., Verhagen Nicole A. M., van Nieuwenhoven Frans A., Blom Ingrid E., Aten Jan, Goldschmeding Roel, Daha Mohamed R., van Kooten Cees Connective tissue growth factor and IGF-I are produced by human renal fibroblasts and cooperate in the induction of collagen production by high glucose Diabetes 2003;52 (12):2975-2983 [PubMed]
  • Kanemoto Katsuyoshi, Usui Joichi, Tomari Shinsuke, Yokoi Hideki, Mukoyama Masashi, Aten Jan, Weening Jan J., Nagata Michio Connective tissue growth factor participates in scar formation of crescentic glomerulonephritis Laboratory investigation; a journal of technical methods and pathology 2003;83 (11):1615-1625 [PubMed]
  • Smit Laura A., Bende Richard J., Aten Jan, Guikema Jeroen E. J., Aarts Wilhelmina M., van Noesel Carel J. M. Expression of activation-induced cytidine deaminase is confined to B-cell non-Hodgkin's lymphomas of germinal-center phenotype Cancer research 2003;63 (14):3894-3898 [PubMed]
  • Roelofs Joris J. T. H., Rowshani Ajda T., van den Berg José G., Claessen Nike, Aten Jan, ten Berge Ineke J. M., Weening Jan J., Florquin Sandrine Expression of urokinase plasminogen activator and its receptor during acute renal allograft rejection Kidney international 2003;64 (5):1845-1853 [PubMed]
  • Spliet Wim G. M., Aronica Eleonora, Ramkema Marja, Aten Jan, Troost Dirk Increased expression of connective tissue growth factor in amyotrophic lateral sclerosis human spinal cord Acta neuropathologica 2003;106 (5):449-457 [PubMed]

2002

  • Bijl M., Dijstelbloem H. M., Oost W. W., Bootsma H., Derksen R. H. W. M., Aten J., Limburg P. C., Kallenberg C. G. M. IgG subclass distribution of autoantibodies differs between renal and extra-renal relapses in patients with systemic lupus erythematosus Rheumatology (Oxford, England) 2002;41 (1):62-67 [PubMed]
  • van den Berg José G., Aten Jan, Annink Carla, Ravesloot Jan H., Weber Ekkehard, Weening Jan J. Interleukin-4 and -13 promote basolateral secretion of H(+) and cathepsin L by glomerular epithelial cells American journal of physiology. Renal physiology 2002;282 (1):F26-F33 [PubMed]

2001

  • van Kooij M., de Groot K., van Vugt H., Aten J., Snoek M. Genotype versus phenotype: conflicting results in mapping a lung tumor susceptibility locus to the G7c recombination interval in the mouse MHC class III region Immunogenetics 2001;53 (8):656-661 [PubMed]
  • Dammers P. M., Bun J. C., Bellon B., Kroese F. G., Aten J., Bos N. A. Immunoglobulin VH-gene usage of autoantibodies in mercuric chloride-induced membranous glomerulopathy in the rat Immunology 2001;103 (2):199-209 [PubMed]
  • Blom I. E., van Dijk A. J., Wieten L., Duran K., Ito Y., Kleij L., deNichilo M., Rabelink T. J., Weening J. J., Aten J., Goldschmeding R. In vitro evidence for differential involvement of CTGF, TGFbeta, and PDGF-BB in mesangial response to injury Nephrology, dialysis, transplantation 2001;16 (6):1139-1148 [PubMed]
  • Ito Y., Goldschmeding R., Bende R., Claessen N., Chand M., Kleij L., Rabelink T., Weening J., Aten J. Kinetics of connective tissue growth factor expression during experimental proliferative glomerulonephritis Journal of the American Society of Nephrology 2001;12 (3):472-484 [PubMed]
  • Florquin S., Roos A., Groothoff J. W., Claessen N., van Gijlswijk-Janssen D. J., Aten J., Davin J. C., Weening J. J. Severe non-proliferative lupus nephritis with predominant sub-endothelial IgA deposits Nephrology, dialysis, transplantation 2001;16 (7):1479-1482 [PubMed]
  • Roos A., Neeft M., Engelen L., Schilder-Tol E. J., Kunzendorf U., Weening J. J., Aten J. The immune dysregulatory compound mercuric chloride induces integrin-mediated T-lymphocyte adhesion Immunology 2001;102 (1):31-38 [PubMed]

2000

  • Goldschmeding R., Aten J., Ito Y., Blom I., Rabelink T., Weening J. J. Connective tissue growth factor: just another factor in renal fibrosis? Nephrology, dialysis, transplantation 2000;15 (3):296-299 [PubMed]
  • de Vree J. M., Ottenhoff R., Bosma P. J., Smith A. J., Aten J., Oude Elferink R. P. Correction of liver disease by hepatocyte transplantation in a mouse model of progressive familial intrahepatic cholestasis Gastroenterology 2000;119 (6):1720-1730 [PubMed]
  • van den Wijngaard R. M., Aten J., Scheepmaker A., Le Poole I. C., Tigges A. J., Westerhof W., Das P. K. Expression and modulation of apoptosis regulatory molecules in human melanocytes: significance in vitiligo British journal of dermatology 2000;143 (3):573-581 [PubMed]
  • van den Berg J. G., Aten J., Chand M. A., Claessen N., Dijkink L., Wijdenes J., Lakkis F. G., Weening J. J. Interleukin-4 and interleukin-13 act on glomerular visceral epithelial cells Journal of the American Society of Nephrology 2000;11 (3):413-422 [PubMed]
  • Aten J., Roos A., Claessen N., Schilder-Tol E. J., ten Berge I. J., Weening J. J. Strong and selective glomerular localization of CD134 ligand and TNF receptor-1 in proliferative lupus nephritis Journal of the American Society of Nephrology 2000;11 (8):1426-1438 [PubMed]

1998

  • Wever P. C., Aten J., Rentenaar R. J., Hack C. E., Koopman G., Weening J. J., ten Berge I. J. Apoptotic tubular cell death during acute renal allograft rejection Clinical nephrology 1998;49 (1):28-34 [PubMed]
  • Roos A., Claessen N., Schilder-Tol E. J., Weening J. J., Aten J. Differential expression of T-cell adhesion molecules and LFA-1-dependent intercellular adhesion in HgCl2-induced autoimmunity and immune suppression Scandinavian journal of immunology 1998;48 (4):389-396 [PubMed]
  • Roos A., Schilder-Tol E. J., Chand M. A., Claessen N., Lakkis F. G., Pascual D. W., Weening J. J., Aten J. Differential regulation of expression of the MHC class II molecules RT1.B and RT1.D on rat B lymphocytes: effects of interleukin-4, interleukin-13 and interferon-gamma Immunology 1998;93 (1):33-40 [PubMed]
  • Ito Y., Aten J., Bende R. J., Oemar B. S., Rabelink T. J., Weening J. J., Goldschmeding R. Expression of connective tissue growth factor in human renal fibrosis Kidney international 1998;53 (4):853-861 [PubMed]
  • de Vree J. M., Jacquemin E., Sturm E., Cresteil D., Bosma P. J., Aten J., Deleuze J. F., Desrochers M., Burdelski M., Bernard O., Oude Elferink R. P., Hadchouel M. Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis Proceedings of the National Academy of Sciences of the United States of America 1998;95 (1):282-287 [PubMed]
  • Roos A., Schilder-Tol E. J., Weening J. J., Aten J. Strong expression of CD134 (OX40), a member of the TNF receptor family, in a T helper 2-type cytokine environment Journal of leukocyte biology 1998;64 (4):503-510 [PubMed]

1997

  • Roos A., Schilder-Tol E. J., Chand M. A., Weening J. J., Aten J. HgCl2 and IL4 differentially modify expression of major histocompatibility complex class II molecules RT1.B and RT1.D in B lymphocytes from brown Norway and Lewis rats Transplantation proceedings 1997;29 (3):1675-1676 [PubMed]
  • Roos A., Claessen N., Schilder-Tol E. J., Chand M. A., Weening J. J., Aten J. Thiol levels in CD134-defined subsets of rat T lymphocytes: possible implications for HgCl2-induced immune dysregulation Biochemical and biophysical research communications 1997;240 (2):452-457 [PubMed]

1996

  • Roos A., Claessen N., Weening J. J., Aten J. Enhanced T lymphocyte expression of LFA-1, ICAM-1, and the TNF receptor family member OX40 in HgCl2-induced systemic autoimmunity Scandinavian journal of immunology 1996;43 (5):507-518 [PubMed]

1995

  • Troost D., Aten J., Morsink F., de Jong J. M. Apoptosis in ALS is not restricted to motoneurons: Bcl-2 expression is increased in post-central cortex, adjacent to the affected motor cortex Journal of the neurological sciences 1995;129 (Suppl):79-80 [PubMed]
  • Troost D., Aten J., Morsink F., de Jong J. M. Apoptosis in amyotrophic lateral sclerosis is not restricted to motor neurons. Bcl-2 expression is increased in unaffected post-central gyrus Neuropathology and applied neurobiology 1995;21 (6):498-504 [PubMed]
  • Aten J., Veninga A., Coers W., Sonnenberg A., Timpl R., Claessen N., van Eendenburg J. D., de Heer E., Weening J. J. Autoantibodies to the laminin P1 fragment in HgCl2-induced membranous glomerulopathy American journal of pathology 1995;146 (6):1467-1480 [PubMed]
  • Aten J., Prigent P., Poncet P., Blanpied C., Claessen N., Druet P., Hirsch F. Mercuric chloride-induced programmed cell death of a murine T cell hybridoma. I. Effect of the proto-oncogene Bcl-2 Cellular immunology 1995;161 (1):98-106 [PubMed]
  • Prigent P., Poncet P., Aten J., Blanpied C., Chand A., Février M., Druet P., Hirsch F. Mercuric chloride-induced programmed cell death of a murine T cell hybridoma. II. Opposite effect of interleukin-2 and interleukin-4 Cellular immunology 1995;161 (1):107-111 [PubMed]
  • van der Meide P. H., de Labie M. C., Botman C. A., Aten J., Weening J. J. Nitric oxide suppresses IFN-gamma production in the spleen of mercuric chloride-exposed brown Norway rats Cellular immunology 1995;161 (2):195-206 [PubMed]
  • van der Meide P. H., Groenestein R. J., de Labie M. C., Aten J., Weening J. J. Susceptibility to mercuric chloride-induced glomerulonephritis is age-dependent: study of the role of IFN-gamma Cellular immunology 1995;162 (1):131-137 [PubMed]

1993

  • Prigent P., Blanpied C., Aten J., Hirsch F. A safe and rapid method for analyzing apoptosis-induced fragmentation of DNA extracted from tissues or cultured cells Journal of immunological methods 1993;160 (1):139-140 [PubMed]
  • van der Meide P. H., de Labie M. C., Botman C. A., van Bennekom W. P., Olsson T., Aten J., Weening J. J. Mercuric chloride down-regulates T cell interferon-gamma production in brown Norway but not in Lewis rats; role of glutathione European journal of immunology 1993;23 (3):675-681 [PubMed]

1992

  • Aten J., Veninga A., Bruijn J. A., Prins F. A., de Heer E., Weening J. J. Antigenic specificities of glomerular-bound autoantibodies in membranous glomerulopathy induced by mercuric chloride Clinical immunology and immunopathology 1992;63 (1):89-102 [PubMed]
  • Aten J., Stet R. J., Wagenaar-Hilbers J. P., Weening J. J., Fleuren G. J., Nieuwenhuis P. Glomerulopathy induced by graft-versus-host reaction in the rat. Requirement of donor CD4+ T lymphocytes and MHC class II incompatibility at the lymphoid compartment Scandinavian journal of immunology 1992;35 (1):93-105 [PubMed]

1991

  • Hoedemaeker P. J., Aten J., Hogendoorn P. C., Kawasaki K., van Leer E. H., de Heer E., Fleuren G. J. Pathogenesis of glomerulonephritis: experimental models revisited Advances in nephrology from the Necker Hospital 1991;20:73-90 [PubMed]
  • Aten J., Veninga A., de Heer E., Rozing J., Nieuwenhuis P., Hoedemaeker P. J., Weening J. J. Susceptibility to the induction of either autoimmunity or immunosuppression by mercuric chloride is related to the major histocompatibility complex class II haplotype European journal of immunology 1991;21 (3):611-616 [PubMed]

1988

  • Aten J., Bosman C. B., de Heer E., Hoedemaeker P. J., Weening J. J. Cyclosporin A induces long-term unresponsiveness in mercuric chloride-induced autoimmune glomerulonephritis Clinical and experimental immunology 1988;73 (2):307-311 [PubMed]
  • Aten J., Bosman C. B., Rozing J., Stijnen T., Hoedemaeker P. J., Weening J. J. Mercuric chloride-induced autoimmunity in the brown Norway rat. Cellular kinetics and major histocompatibility complex antigen expression American journal of pathology 1988;133 (1):127-138 [PubMed]

1985

  • Kroese F. G., Opstelten D., Wubbena A. S., Deenen G. J., Aten J., Schwander E. H., de Leij L., Nieuwenhuis P. Monoclonal antibodies to rat B lymphocyte (sub-)populations Advances in experimental medicine and biology 1985;186:81-89 [PubMed]