R.M.J.G.J. van den Wijngaard PhD publications

2020

• Antonioli Luca, D'Antongiovanni Vanessa, Pellegrini Carolina, Fornai Matteo, Benvenuti Laura, di Carlo Alma, van den Wijngaard Renè, Caputi Valentina, Cerantola Silvia, Giron Maria Cecilia, Németh Zoltán H., Haskó György, Blandizzi Corrado, Colucci Rocchina Colonic dysmotility associated with high-fat diet-induced obesity: Role of enteric glia FASEB journal 2020;34 (4):5512-5524 [PubMed]
• D'Antongiovanni Vanessa, Benvenuti Laura, Fornai Matteo, Pellegrini Carolina, van den Wijngaard Renè, Cerantola Silvia, Giron Maria Cecilia, Caputi Valentina, Colucci Rocchina, Haskó Gyorgy, Németh Zoltán H., Blandizzi Corrado, Antonioli Luca Glial A2B Adenosine Receptors Modulate Abnormal Tachykininergic Responses and Prevent Enteric Inflammation Associated with High Fat Diet-Induced Obesity Cells 2020;9 (5) [PubMed]
• Botschuijver Sara Gut fungi in irritable bowel syndrome: A painful recognition 2020. 236p. ISBN 9789402818871. [UvA Dissertations Online] University of Amsterdam. (Supervisors: de Jonge Wouter .J,; Co-supervisors: Seppen Jurgen.E., van den Wijngaard Renoldus M. J. G. J.)
• van Thiel Isabelle A. M., de Jonge Wouter J., Chiu Isaac M., van den Wijngaard Rene M. Microbiota-neuroimmune cross talk in stress-induced visceral hypersensitivity of the bowel American journal of physiology. Gastrointestinal and liver physiology 2020;318 (6):G1034-G1041 [PubMed]

2019

• Botschuijver Sara, van Diest Sophie A., van Thiel Isabelle A. M., Saia Rafael S., Strik Anne S., Yu Zhumei, Maria-Ferreira Daniele, Welting Olaf, Keszthelyi Daniel, Jennings Gary, Heinsbroek Sigrid E. M., Elferink Ronald P. Oude, Schuren Frank H. J., de Jonge Wouter J., van den Wijngaard René M. Miltefosine treatment reduces visceral hypersensitivity in a rat model for irritable bowel syndrome via multiple mechanisms Scientific reports 2019;9 (1) [PubMed]
• van Diest Sophie A. The pain behind visceral hypersensitivity in IBS 2019. 147p. ISBN 9789402815498. [UvA Dissertations Online] University of Amsterdam. (Supervisor: de Jonge W. J.; Co-supervisor: van den Wijngaard R. M. J. G. J.)

2018

• Warners Marijn J., Terreehorst Ingrid, van den Wijngaard René M., Akkerdaas Jaap, van Esch Betty C. A. M., van Ree Ronald, Versteeg Serge A., Smout Andreas J. P. M., Bredenoord Albert J. Abnormal Responses to Local Esophageal Food Allergen Injections in Adult Patients With Eosinophilic Esophagitis Gastroenterology 2018;154 (1):57-+ [PubMed]
• Fornai M., van den Wijngaard R. M., Antonioli L., Pellegrini C., Blandizzi C., de Jonge W. J. Neuronal regulation of intestinal immune functions in health and disease Neurogastroenterology and motility 2018;30 (12):e13406 [PubMed]
• Botschuijver S., Welting O., Levin E., Maria-Ferreira D., Koch E., Montijn R. C., Seppen J., Hakvoort T. B. M., Schuren F. H. J., de Jonge W. J., van den Wijngaard R. M. Reversal of visceral hypersensitivity in rat by Menthacarin , a proprietary combination of essential oils from peppermint and caraway, coincides with mycobiome modulation Neurogastroenterology and motility 2018;30 (6):e13299 [PubMed]
• Maria-Ferreira Daniele, Nascimento Adamara Machado, Cipriani Thales Ricardo, Santana-Filho Arquimedes Paixão, Watanabe Paulo da Silva, Sant´Ana Debora de Mello Gonçales, Luciano Fernando Bittencourt, Bocate Karla Carolina Paiva, van den Wijngaard René M., Werner Maria Fernanda de Paula, Baggio Cristiane Hatsuko Rhamnogalacturonan, a chemically-defined polysaccharide, improves intestinal barrier function in DSS-induced colitis in mice and human Caco-2 cells Scientific reports 2018;8 (1) [PubMed]

2017

• Botschuijver Sara, Roeselers Guus, Levin Evgeni, Jonkers Daisy M., Welting Olaf, Heinsbroek Sigrid E. M., de Weerd Heleen H., Boekhout Teun, Fornai Matteo, Masclee Ad A., Schuren Frank H. J., de Jonge Wouter J., Seppen Jurgen, van den Wijngaard René M. Intestinal Fungal Dysbiosis Is Associated With Visceral Hypersensitivity in Patients With Irritable Bowel Syndrome and Rats Gastroenterology 2017;153 (4):1026-1039 [PubMed]
• Dhawan Shobhit Neural regulation of innate and adaptive immunity in the gut 2017. 189p. ISBN 9789462955462. [UvA Dissertations Online] University of Amsterdam. (Supervisor: de Jonge W. J.; Co-supervisor: van den Wijngaard R. M. J. G. J.)

2016

• Botschuijver Sara, Yu Zhumei, Welting Olaf, Cailotto Cathy, Kalsbeek Andries, van den Wijngaard Rene Absence of diurnal variation in visceromotor response to colorectal distention in normal Long Evans rats F1000Research 2016;5:98 [PubMed]
• Dhawan Shobhit, de Palma Giada, Willemze Rose A., Hilbers Francisca W., Verseijden Caroline, Luyer Misha D., Nuding Sabine, Wehkamp Jan, Souwer Yuri, de Jong Esther C., Seppen J., van den Wijngaard René M., Wehner Sven, Verdu Elena, Bercik Premek, de Jonge Wouter J. Acetylcholine-producing T cells in the intestine regulate antimicrobial peptide expression and microbial diversity American journal of physiology. Gastrointestinal and liver physiology 2016;311 (5):G920-G933 [PubMed]
• van Hoeij Froukje B., Weijenborg Pim W., van den Bergh Weerman Marius A., van den Wijngaard René M. J. G. J., Verheij J., Smout André J. P. M., Bredenoord Albert J. Mucosal integrity and sensitivity to acid in the proximal esophagus in patients with gastroesophageal reflux disease American journal of physiology. Gastrointestinal and liver physiology 2016;311 (1):G117-G122 [PubMed]

2015

• van Diest Sophie A., van den Elsen Lieke W. J., Klok Allison J., Welting Olaf, Hilbers Francisca W., van de Heijning Bert J., Gaemers Ingrid C., Boeckxstaens Guy E., Werner Maria F., Willemsen Linette E. M., de Jonge Wouter J., van den Wijngaard René M. Dietary Marine n-3 PUFAs Do Not Affect Stress-Induced Visceral Hypersensitivity in a Rat Maternal Separation Model Journal of nutrition 2015;145 (5):915-922 [PubMed]
• van Rhijn Bram D., Verheij Joanne, van den Bergh Weerman Marius A., Verseijden Caroline, van den Wijngaard René M. J. G. J., de Jonge Wouter J., Smout Andreas J. P. M., Bredenoord Albert J. Histological Response to Fluticasone Propionate in Patients With Eosinophilic Esophagitis Is Associated With Improved Functional Esophageal Mucosal Integrity American journal of gastroenterology 2015;110 (9):1289-1297 [PubMed]

2014

• Stănişor Oana I. Pathophysiology of stress-induced visceral hypersensitivity 2014. 113p. ISBN 9789789462035. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Boeckxstaens G. E. E.; Co-supervisor: van den Wijngaard R. M. J. G. J.)
• van Rhijn Bram D., Weijenborg Pim W., Verheij Joanne, van den Bergh Weerman Marius A., Verseijden Caroline, van den Wijngaard René M. J. G. J., de Jonge Wouter J., Smout Andreas J. P. M., Bredenoord Albert J. Proton pump inhibitors partially restore mucosal integrity in patients with proton pump inhibitor-responsive esophageal eosinophilia but not eosinophilic esophagitis Clinical gastroenterology and hepatology 2014;12 (11):1815-23.e2 [PubMed]

2013

• Stanisor Oana I., van Diest Sophie A., Yu Zhumei, Welting Olaf, Bekkali Noor, Shi Jing, de Jonge Wouter J., Boeckxstaens Guy E., van den Wijngaard Rene M. Stress-induced visceral hypersensitivity in maternally separated rats can be reversed by peripherally restricted histamine-1-receptor antagonists PLoS ONE 2013;8 (6):e66884 [PubMed]
• van den Wijngaard R. M., Stanisor O. I., van Diest S. A., Welting O., Wouters M. M., Cailotto C., de Jonge W. J., Boeckxstaens G. E. Susceptibility to stress induced visceral hypersensitivity in maternally separated rats is transferred across generations Neurogastroenterology and motility 2013;25 (12):e780-e790 [PubMed]

2012

• Wouters M. M., van Wanrooy S., Casteels C., Nemethova A., de Vries A., van Oudenhove L., van den Wijngaard R. M., van Laere K., Boeckxstaens G. Altered brain activation to colorectal distention in visceral hypersensitive maternal-separated rats Neurogastroenterology and motility 2012;24 (7):678-e297 [PubMed]
• Braak Breg How stress affects the digestive tract. Unravelling the pathofysiology of functional bowel disorders 2012. 167p. ISBN 9789461908209. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Boeckxstaens G. E.; Co-supervisor: van den Wijngaard R. M. J. G. J.)
• de Winter Benedicte Y., van den Wijngaard Rene M., de Jonge Wouter J. Intestinal mast cells in gut inflammation and motility disturbances BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 2012;1822 (1):66-73 [PubMed]
• Snoek S. A., Dhawan S., van Bree S. H., Cailotto C., van Diest S. A., Duarte J. M., Stanisor O. I., Hilbers F. W., Nijhuis L., Koeman A., van den Wijngaard R. M., Zuurbier C. J., Boeckxstaens G. E., de Jonge W. J. Mast cells trigger epithelial barrier dysfunction, bacterial translocation and postoperative ileus in a mouse model Neurogastroenterology and motility 2012;24 (2):172-E91 [PubMed]
• Braak Breg, Klooker Tamira K., Wouters Mira M., Welting Olaf, van der Loos Chris M., Stanisor Oana I., van Diest Sophie, van den Wijngaard Rene M., Boeckxstaens Guy E. Mucosal Immune Cell Numbers and Visceral Sensitivity in Patients With Irritable Bowel Syndrome: Is There Any Relationship American journal of gastroenterology 2012;107 (5):715-726 [PubMed]
• van der Zanden Esmerij P., Hilbers Francisca W., Verseijden Caroline, van den Wijngaard Rene M., Skynner Mike, Lee Kevin, Ulloa Luis, Boeckxstaens Guy E., de Jonge Wouter J. Nicotinic Acetylcholine Receptor Expression and Susceptibility to Cholinergic Immunomodulation in Human Monocytes of Smoking Individuals Neuroimmunomodulation 2012;19 (4):255-265 [PubMed]
• van den Wijngaard R. M., Stanisor O. I., van Diest S. A., Welting O., Wouters M. M., de Jonge W. J., Boeckxstaens G. E. Peripheral a-helical CRF (9-41) does not reverse stress-induced mast cell dependent visceral hypersensitivity in maternally separated rats Neurogastroenterology and motility 2012;24 (3):274-E111 [PubMed]
• van Diest Sophie A., Stanisor Oana I., Boeckxstaens Guy E., de Jonge Wouter J., van den Wijngaard René M. Relevance of mast cell-nerve interactions in intestinal nociception BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 2012;1822 (1):74-84 [PubMed]
• de Jonge Wouter J., van den Wijngaard René M. Special issue on mast cells in inflammation Preface BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 2012;1822 (1):1 [PubMed]
• Braak Breg, Booij Jan, Klooker Tamira K., van den Wijngaard Rene M. J., Boeckxstaens Guy E. E. The dopaminergic system in patients with functional dyspepsia analysed by single photon emission computed tomography (SPECT) and an alpha-methyl-para-tyrosine (AMPT) challenge test European journal of nuclear medicine and molecular imaging 2012;39 (4):642-650 [PubMed]

2011

• Braak B., Klooker T. K., Wouters M. M., Lei A., van den Wijngaard R. M., Boeckxstaens G. E. Randomised clinical trial: the effects of amitriptyline on drinking capacity and symptoms in patients with functional dyspepsia, a double-blind placebo-controlled study Alimentary pharmacology & therapeutics 2011;34 (6):638-648 [PubMed]
• Wouters Mira M., Klooker Tamira K., van den Wijngaard Rene M., Boeckxstaens Guy E. Reply Gastroenterology 2011;140 (7):2136
• Klooker T. K., Leliefeld K. E. M., van den Wijngaard R. M., Boeckxstaens G. E. E. The cannabinoid receptor agonist delta-9-tetrahydrocannabinol does not affect visceral sensitivity to rectal distension in healthy volunteers and IBS patients Neurogastroenterology and motility 2011;23 (1):30-E2 [PubMed]
• Bekkali N., de Jonge H. R., van den Wijngaard R. M. J. G. J., van der Steeg A. F. W., Bijlsma P. B., Taminiau J. A. J. M., Desjeux J. F., Benninga M. A. The role of rectal chloride secretion in childhood constipation Neurogastroenterology and motility 2011;23 (11):1007-1012 [PubMed]
• van Diest Sophie A., Stanisor Oana I., de Jonge Wouter J., Boeckxstaens Guy E., van den Wijngaard René M. Visceral hypersensitivity in IBS: from bench to bedside Journal of pediatric gastroenterology and nutrition 2011;53 (Suppl. 2):S34-S35 [PubMed]

2010

• Snoek Susanne A., Borensztajn Keren S., van den Wijngaard René M., de Jonge Wouter J. Neuropeptide Receptors in Intestinal Disease: Physiology and Therapeutic Potential Current pharmaceutical design 2010;16 (9):1091-1105 [PubMed]
• van den Wijngaard René M., Klooker Tamira K., de Jonge Wouter J., Boeckxstaens Guy E. Peripheral relays in stress-induced activation of visceral afferents in the gut Autonomic neuroscience 2010;153 (1-2):99-105 [PubMed]
• Snoek Susanne A., Verstege Marleen I., Boeckxstaens Guy E., van den Wijngaard René M., de Jonge Wouter J. The enteric nervous system as a regulator of intestinal epithelial barrier function in health and disease Expert review of gastroenterology & hepatology 2010;4 (5):637-651 [PubMed]
• Klooker Tamira K., Braak Breg, Koopman Karin E., Welting Olaf, Wouters Mira M., van der Heide Sicco, Schemann Michael, Bischoff Stephan C., van den Wijngaard Rene M., Boeckxstaens Guy E. The mast cell stabiliser ketotifen decreases visceral hypersensitivity and improves intestinal symptoms in patients with irritable bowel syndrome Gut 2010;59 (9):1213-1221 [PubMed]

2009

• van den Wijngaard R. M., Klooker T. K., Welting O., Stanisor O. I., Wouters M. M., van der Coelen D., Bulmer D. C., Peeters P. J., Aerssens J., de Hoogt R., Lee K., de Jonge W. J., Boeckxstaens G. E. Essential role for TRPV1 in stress-induced (mast cell-dependent) colonic hypersensitivity in maternally separated rats Neurogastroenterology and motility 2009;21 (10):1107-1e94 [PubMed]
• Klooker Tamira K., Braak Breg, Painter Rebecca C., de Rooij Susanne R., van Elburg Ruurd M., van den Wijngaard Rene M., Roseboom Tessa J., Boeckxstaens Guy E. Exposure to Severe Wartime Conditions in Early Life Is Associated With an Increased Risk of Irritable Bowel Syndrome: A Population-Based Cohort Study American journal of gastroenterology 2009;104 (9):2250-2256 [PubMed]
• van den Wijngaard R. M., Welting O., Bulmer D. C., Wouters M. M., Lee K., de Jonge W. J., Boeckxstaens G. E. Possible role for TRPV1 in neomycin-induced inhibition of visceral hypersensitivity in rat Neurogastroenterology and motility 2009;21 (8):863-e60 [PubMed]
• The Frans O., Buist Marrije R., Lei Aaltje, Bennink Roelof J., Hofland Jan, van den Wijngaard René M., de Jonge Wouter J., Boeckxstaens Guy E. The role of mast cell stabilization in treatment of postoperative ileus: a pilot study American journal of gastroenterology 2009;104 (9):2257-2266 [PubMed]
• Klooker Tamira K. Visceral hypersensitivity in the irritable bowel syndrome. Exploring the stress - mast cell - iinflammation hypothesis 2009. 184p. ISBN 9789090245805. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Boeckxstaens G. E. E.; Co-supervisor: van den Wijngaard R. M. J. G. J.)

2008

• Ivanova Krassimira, Lambers Britta, van den Wijngaard Rene, Le Poole I. Caroline, Grigorieva Olga, Gerzer Rupert, Das Pranab K. Immortalization of human melanocytes does not alter the de novo properties of nitric oxide to induce cell detachment from extracellular matrix components via cGMP In vitro cellular & developmental biology. Animal 2008;44 (8-9):385-395 [PubMed]
• The F. O., Bennink R. J., Ankum W. M., Buist M. R., Busch O. R. C., Gouma D. J., van der Heide S., van den Wijngaard R. M., de Jonge W. J., Boeckxstaens G. E. Intestinal handling-induced mast cell activation and inflammation in human postoperative ileus Gut 2008;57 (1):33-40 [PubMed]

2007

• The Frans O., Boeckxstaens Guy E., Snoek Susanne A., Cash Jenna L., Bennink Roel, Larosa Gregory J., van den Wijngaard Rene M., Greaves David R., de Jonge Wouter J. Activation of the cholinergic anti-inflammatory pathway ameliorates postoperative ileus in mice Gastroenterology 2007;133 (4):1219-1228 [PubMed]
• van den Elzen Bram D., van den Wijngaard Rene M., Tytgat Guido N., Boeckxstaens Guy E. E. Influence of corticotropin-releasing hormone on gastric sensitivity and motor function in healthy volunteers European journal of gastroenterology & hepatology 2007;19 (5):401-407 [PubMed]

2005

• Boeckxstaens Guy E., de Jonge Wouter, van den Wijngaard René M., Benninga Marc A. Achalasia: From new insights in pathophysiology to treatment Journal of pediatric gastroenterology and nutrition 2005;41 (Suppl. 1):S36-S37 [PubMed]
• Welting O., van den Wijngaard R. M., de Jonge W. J., Holman R., Boeckxstaens G. E. Assessment of visceral sensitivity using radio telemetry in a rat model of maternal separation Neurogastroenterology and motility 2005;17 (6):838-845 [PubMed]
• de Jonge Wouter J., The Frans O., van der Zanden Esmerij P., van den Wijngaard René M., Boeckxstaens Guy E. Inflammation and gut motility; Neural control of intestinal immune cell activation Journal of pediatric gastroenterology and nutrition 2005;41 (Suppl. 1):S10-S11 [PubMed]
• Ivanova Krassimira, van den Wijngaard Rene, Gerzer Rupert, Lamers Wouter H., Das Pranab K. Non-lesional vitiliginous melanocytes are not characterized by an increased proneness to nitric oxide-induced apoptosis Experimental dermatology 2005;14 (6):445-453 [PubMed]
• van den Wijngaard René, Welting Olaf, de Jonge Wouter, Boeckxstaens Guy Parental care, mast cells and visceral hypersensitivity Journal of pediatric gastroenterology and nutrition 2005;41 (Suppl. 1):S12-S13 [PubMed]
• de Jonge Wouter J., van der Zanden Esmerij P., The Frans O., Bijlsma Maarten F., van Westerloo David J., Bennink Roelof J., Berthoud Hans-Rudolf, Uematsu Satoshi, Akira Shizuo, van den Wijngaard Rene M., Boeckxstaens Guy E. Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway Nature immunology 2005;6 (8):844-851 [PubMed]
• de Jonge W. J., van der Zanden E. P., O The F., Bijlsma M. F., van Westerloo D. J., Bennink R. J., Berthoud H. R., Uematsu S., Akira S., van den Wijngaard R. M., Boeckxstaens G. E. Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway (vol 6, pg 844, 2005) Nature immunology 2005;6 (9):954
• The Frans O., de Jonge Wouter J., Bennink Roel J., van den Wijngaard Rene M., Boeckxstaens Guy E. The ICAM-1 antisense oligonucleotide ISIS-3082 prevents the development of postoperative ileus in mice British journal of pharmacology 2005;146 (2):252-258 [PubMed]

2004

• Le Poole I. Caroline, Wañkowicz-Kaliñska Anna, van den Wijngaard René M. J. G. J., Nickoloff Brian J., Das Pranab K. Autoimmune aspects of depigmentation in vitiligo journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2004;9 (1):68-72 [PubMed]
• de Jonge Wouter J., The Frans O., van der Coelen Dennis, Bennink Roelof J., Reitsma Pieter H., van Deventer Sander J., van den Wijngaard René M., Boeckxstaens Guy E. Mast cell degranulation during abdominal surgery initiates postoperative ileus in mice Gastroenterology 2004;127 (2):535-545 [PubMed]

2003

• Wańkowicz-Kalińska Anna, van den Wijngaard René M. J. G. J., Tigges Bert J., Westerhof Wiete, Ogg Graham S., Cerundolo Vincenzo, Storkus Walter J., Das Pranab K. Immunopolarization of CD4(+) and CD8(+) T cells to type-1-like is associated with melanocyte loss in human vitiligo Laboratory investigation; a journal of technical methods and pathology 2003;83 (5):683-695 [PubMed]
• Wankowicz-Kalinska Anna, Le Poole Caroline, van den Wijngaard Rene, Storkus Walter J., Das Pranab K. Melanocyte-specific immune response in melanoma and vitiligo: two faces of the same coin? Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2003;16 (3):254-260 [PubMed]
• de Jonge Wouter J., van den Wijngaard René M., The Frans O., ter Beek Merel-Linde, Bennink Roel J., Tytgat Guido N. J., Buijs Ruud M., Reitsma Pieter H., van Deventer Sander J., Boeckxstaens Guy E. Postoperative ileus is maintained by intestinal immune infiltrates that activate inhibitory neural pathways in mice Gastroenterology 2003;125 (4):1137-1147 [PubMed]
• Bennink Roelof J., de Jonge Wouter J., Symonds Erin L., van den Wijngaard Rene M., Spijkerboer Astrid L., Benninga Marc A., Boeckxstaens Guy E. Validation of gastric-emptying scintigraphy of solids and liquids in mice using dedicated animal pinhole scintigraphy Journal of nuclear medicine 2003;44 (7):1099-1104 [PubMed]

2002

• van den Wijngaard R. M. J. G. J., Asghar S. S., Pijnenborg A. C. L. M., Tigges A. J., Westerhof W., Das P. K. Aberrant expression of complement regulatory proteins, membrane cofactor protein and decay accelerating factor, in the involved epidermis of patients with vitiligo British journal of dermatology 2002;146 (1):80-87 [PubMed]

2001

• Das P. K., van den Wijngaard R. M., Wankowicz-Kalinska A., Le Poole I. C. A symbiotic concept of autoimmunity and tumour immunity: lessons from vitiligo Trends in immunology 2001;22 (3):130-136 [PubMed]
• van den Wijngaard R., Wankowicz-Kalinska A., Pals S., Weening J., Das P. Autoimmune melanocyte destruction in vitiligo Laboratory investigation; a journal of technical methods and pathology 2001;81 (8):1061-1067 [PubMed]
• Ivanova K., Das P. K., van den Wijngaard R. M., Lenz W., Klockenbring T., Malcharzyk V., Drummer C., Gerzer R. Differential expression of functional guanylyl cyclases in melanocytes: absence of nitric-oxide-sensitive isoform in metastatic cells Journal of investigative dermatology 2001;116 (3):409-416 [PubMed]

2000

• Boeckxstaens G. E., Hollmann M., Heisterkamp S. H., Robberecht P., de Jonge W. J., van den Wijngaard R. M., Tytgat G. N., Blommaart P. J. Evidence for VIP(1)/PACAP receptors in the afferent pathway mediating surgery-induced fundic relaxation in the rat British journal of pharmacology 2000;131 (4):705-710 [PubMed]
• van den Wijngaard R. M., Aten J., Scheepmaker A., Le Poole I. C., Tigges A. J., Westerhof W., Das P. K. Expression and modulation of apoptosis regulatory molecules in human melanocytes: significance in vitiligo British journal of dermatology 2000;143 (3):573-581 [PubMed]
• van den Wijngaard R., Wankowicz-Kalinska A., Le poole C., Tigges B., Westerhof W., Das P. Local immune response in skin of generalized vitiligo patients. Destruction of melanocytes is associated with the prominent presence of CLA+ T cells at the perilesional site Laboratory investigation; a journal of technical methods and pathology 2000;80 (8):1299-1309 [PubMed]

1997

• Le Poole I. C., van den Berg F. M., van den Wijngaard R. M., Galloway D. A., van Amstel P. J., Buffing A. A., Smits H. L., Westerhof W., Das P. K. Generation of a human melanocyte cell line by introduction of HPV16 E6 and E7 genes In vitro cellular & developmental biology. Animal 1997;33 (1):42-49 [PubMed]
• Teunissen M. B., Koomen C. W., Jansen J., de Waal Malefyt R., Schmitt E., van den Wijngaard R. M., Das P. K., Bos J. D. In contrast to their murine counterparts, normal human keratinocytes and human epidermoid cell lines A431 and HaCaT fail to express IL-10 mRNA and protein Clinical and experimental immunology 1997;107 (1):213-223 [PubMed]
• Le Poole I. C., van den Wijngaard R. M., Westerhof W., Das P. K. Tenascin is overexpressed in vitiligo lesional skin and inhibits melanocyte adhesion British journal of dermatology 1997;137 (2):171-178 [PubMed]

1996

• Le Poole I. C., van den Wijngaard R. M., Verkruisen R. P., Lamers W. H., Troost D., Westerhof W., Das P. K. Foetal human melanocytes: in situ detection, in vitro culture and differentiation characteristics at 6-11 weeks EGA Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 1996;9 (3):126-133 [PubMed]
• Le Poole I. C., van den Wijngaard R. M., Westerhof W., Das P. K. Presence of T cells and macrophages in inflammatory vitiligo skin parallels melanocyte disappearance American journal of pathology 1996;148 (4):1219-1228 [PubMed]

1994

• Le Poole I. C., van den Wijngaard R. M., Smit N. P., Oosting J., Westerhof W., Pavel S. Catechol-O-methyltransferase in vitiligo Archives of dermatological research 1994;286 (2):81-86 [PubMed]
• Le Poole I. C., van den Wijngaard R. M., Westerhof W., Dormans J. A., van den Berg F. M., Verkruisen R. P., Dingemans K. P., Das P. K. Organotypic culture of human skin to study melanocyte migration Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 1994;7 (1):33-43 [PubMed]

1993

• Le Poole I. C., Mutis T., van den Wijngaard R. M., Westerhof W., Ottenhoff T., de Vries R. R., Das P. K. A novel, antigen-presenting function of melanocytes and its possible relationship to hypopigmentary disorders Journal of immunology (Baltimore, Md. 1993;151 (12):7284-7292 [PubMed]
• Smit N., Le Poole I., van den Wijngaard R., Tigges A., Westerhof W., Das P. Expression of different immunological markers by cultured human melanocytes Archives of dermatological research 1993;285 (6):356-365 [PubMed]
• Le Poole I. C., van den Wijngaard R. M., Westerhof W., Verkruisen R. P., Dutrieux R. P., Dingemans K. P., Das P. K. Phagocytosis by normal human melanocytes in vitro Experimental cell research 1993;205 (2):388-395 [PubMed]
• Le Poole I. C., van den Wijngaard R. M., Westerhof W., Dutrieux R. P., Das P. K. Presence or absence of melanocytes in vitiligo lesions: an immunohistochemical investigation Journal of investigative dermatology 1993;100 (6):816-822 [PubMed]
• Le Poole I. C., Das P. K., van den Wijngaard R. M., Bos J. D., Westerhof W. Review of the etiopathomechanism of vitiligo: a convergence theory Experimental dermatology 1993;2 (4):145-153 [PubMed]