Prof. R.O. Schlingemann MD PhD publications

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Publications Prof. MD PhD R.O. Schlingemann

Position
Medical Specialist
Main activities
Patient care, Research
Specialisation
Ophthalmology
Focus of research
  • The role of angiogenic and anti-angiogenic factors in ocular angiogenesis, particularly in AMD and diabetic retinopathy
  • The cellular mechanisms underlying loss of the blood-retinal barrier in diabetic retinopathy
  • Identification of new genes and mechanisms of angiogenesis
  • The role of complement activation and the proteasome in retinal pigment epithelium in the early stages of age-related macular degeneration
  • Prospective clinical trials on the use of anti-angiogenic therapy in AMD, diabetic retinopathy and retinal vein occlusions

See also: www.ocular-angiogenesis.nl/

2021

  • Yetkin-Arik Bahar, Kastelein Arnoud W., Klaassen Ingeborg, Jansen Charlotte H. J. R., Latul Yani P., Vittori Miloš, Biri Aydan, Kahraman Korhan, Griffioen Arjan W., Amant Frederic, Lok Christianne A. R., Schlingemann Reinier O., van Noorden Cornelis J. F. Angiogenesis in gynecological cancers and the options for anti-angiogenesis therapy BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER 2021;1875 (1) [PubMed]
  • Wenstedt Eliane F. E., Beugelink Lisanne, Schrooten Esmee M., Rademaker Emma, Rorije Nienke M. G., Wouda Rosa D., Schlingemann Reinier O., Wong Tien Y., Vogt Liffert High-salt intake affects retinal vascular tortuosity in healthy males: an exploratory randomized cross-over trial Scientific reports 2021;11 (1) [PubMed]
  • Arik-Yetkin Bahar Tip cell: whose side are you on?: Endothelial tip cells and non-tip cells in angiogenesis 2021. 229p. ISBN 9789464162028. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Schlingemann Reinier O., van Noorden Cornelis J. F.; Co-supervisor: Klaassen Ingeborg)

2020

  • Vader Maartje J. C., Schauwvlieghe Ann-Sofie M. E., Verbraak Frank D., Dijkman Greetje, Hooymans Johanna M. M., Los Leonoor I., Zwinderman Aeilko H., Peto Tunde, Hoyng Carel B., van Leeuwen Redmer, Vingerling Johannes R., Moll Annette C., van Lith-Verhoeven Janneke J. C., Dijkgraaf Marcel G. W., Schlingemann Reinier O. Comparing the Efficacy of Bevacizumab and Ranibizumab in Patients with Diabetic Macular Edema (BRDME): The BRDME Study, a Randomized Trial Ophthalmology Retina 2020;4 (8):777-788 [PubMed]
  • Vader Maartje J. C., Schauwvlieghe Ann-Sofie M. E., Verbraak Frank D., Dijkman Greetje, Hooymans Johanna M. M., Los Leonoor I., Zwinderman Aeilko H., Peto Tunde, Hoyng Carel B., van Leeuwen Redmer, Vingerling Johannes R., de Jong-Hesse Yvonne, van Lith-Verhoeven Janneke J. C., Dijkgraaf Marcel G. W., Schlingemann Reinier O. Comparing the Efficacy of Bevacizumab and Ranibizumab in Patients with Retinal Vein Occlusion: The Bevacizumab to Ranibizumab in Retinal Vein Occlusions (BRVO) study, a Randomized Trial Ophthalmology Retina 2020;4 (6):576-587 [PubMed]
  • Dallinga Marchien G. Endothelial tip cells in culture: An in vitro approach for studies of angiogenesis 2020. 285p. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van Noorden Cornelis J. F., Schlingemann Reinier O.; Co-supervisor: Klaassen Ingeborg)
  • Ramos de Carvalho Emanuel E., Hoveling Richelle J. M., van Noorden Cornelis J. F., Schlingemann Reinier O., Aalders Maurice C. G. Functional Imaging of the Ocular Fundus Using an 8-Band Retinal Multispectral Imaging System. Instruments 2020;4 (2)
  • Stehouwer Marilette, Schlingemann Reinier O., Verbraak Frank D. High recurrence rate in patients with choroidal hemangioma treated with limited single spot photodynamic therapy during long-term follow-up Acta ophthalmologica 2020;98 (7):679-686 [PubMed]
  • Dallinga Marchien G., Habani Yasmin I., Kayser Richelle P., van Noorden Cornelis J. F., Klaassen Ingeborg, Schlingemann Reinier O. IGF-binding proteins 3 and 4 are regulators of sprouting angiogenesis Molecular biology reports 2020;47 (4):2561-2572 [PubMed]
  • van Loghem Jani A. J. Improving patient safety during facial filler treatments in aesthetic medicine 2020. 249p. [UvA Dissertations Online] (Supervisor: Schlingemann Reinier O.; Co-supervisor: Saeed Peerooz)
  • Verbraak Frank D., Schmidt-Erfurth Ursula, Grzybowski Andrzej, Abramoff Michael, Schlingemann Reinier Is automated screening for diabetic retinopathy indeed not yet ready as stated by Grauslund et al.? Acta ophthalmologica 2020;98 (2):e257-e258 [PubMed]
  • Friedrich Julian, Steel David H. W., Schlingemann Reinier O., Koss Michael J., Hammes Hans-Peter, Krenning Guido, Klaassen Ingeborg MicroRNA expression profile in the vitreous of proliferative diabetic retinopathy patients and differences from patienttreated with anti-VEGF therapy Translational Vision Science and Technology 2020;9 (6):1-10 [PubMed]
  • Darma Stanley, van den Berg Thomas J. T. P., Kok Pauline H. B., Hulsman Caroline A., Mourits Maarten P., Schlingemann Reinier O., Verbraak Frank D. Quality factor based correction for SD-OCT measurements in cataract patients Acta ophthalmologica 2020;98 (1):43-47 [PubMed]

2019

  • van Rijssen Thomas J., van Dijk Elon H. C., Yzer Suzanne, Ohno-Matsui K., Keunen Jan E. E., Schlingemann Reinier O., Sivaprasad S., Querques Giuseppe, Downes Susan M., Fauser Sascha, Hoyng Carel B., Piccolino Felice Cardillo, Chhablani J. K., Lai Timothy Y. Y., Lotery Andrew J., Larsen Michael, Holz Frank G., Freund K. Bailey, Yannuzzi Lawrence A., Boon Camiel J. F. Central serous chorioretinopathy: Towards an evidence-based treatment guideline Progress in retinal and eye research 2019;73 [PubMed]
  • Verbraak Frank D., Abramoff Michael D., Bausch Gonny C. F., Klaver Caroline, Nijpels Giel, Schlingemann Reinier O., van der Heijden Amber A. Diagnostic accuracy of a device for the automated detection of diabetic retinopathy in a primary care setting Diabetes care 2019;42 (4):651-656 [PubMed]
  • Yetkin-Arik B., Vogels I. M. C., Neyazi N., van Duinen V., Houtkooper R. H., van Noorden C. J. F., Klaassen I., Schlingemann R. O. Endothelial tip cells in vitro are less glycolytic and have a more flexible response to metabolic stress than non-tip cells Scientific reports 2019;9 (1):10414 [PubMed]
  • van der Wijk Anne-Eva, Wisniewska-Kruk Joanna, Vogels Ilse M. C., van Veen Henk A., Ip Wing Fung, van der Wel Nicole N., van Noorden Cornelis J. F., Schlingemann Reinier O., Klaassen Ingeborg Expression patterns of endothelial permeability pathways in the development of the blood-retinal barrier in mice FASEB journal 2019;33 (4):5320-5333 [PubMed]
  • van der Wijk Anne-Eva, Canning Paul, van Heijningen Rutger P., Vogels Ilse M. C., van Noorden Cornelis J. F., Klaassen Ingeborg, Schlingemann Reinier O. Glucocorticoids exert differential effects on the endothelium in an in vitro model of the blood–retinal barrier Acta ophthalmologica 2019;97 (2):214-224 [PubMed]
  • van Noort Baudine C., Keunen Jan E. E., Schlingemann Reinier O., Marinkovic Marina Long Survival and Preservation of Good Visual Acuity in a Patient with Bilateral Diffuse Uveal Melanocytic Proliferation Ocular Oncology and Pathology 2019;5 (1):75-78 [PubMed]
  • Schmid Martin K., Thiel Michael A., Lienhard Kenny, Schlingemann Reinier O., Faes Livia, Bachmann Lucas M. Reliability and diagnostic performance of a novel mobile app for hyperacuity self-monitoring in patients with age-related macular degeneration Eye (London, England) 2019;33:1584-1589 [PubMed]
  • Faes Livia, Bodmer Nicolas S., Locher Silvan, Keane Pearse A., Balaskas Konstantinos, Bachmann Lucas M., Schlingemann Reinier O., Schmid Martin K. Test performance of optical coherence tomography angiography in detecting retinal diseases: a systematic review and meta-analysis Eye (London, England) 2019;33 (8):1327-1338 [PubMed]
  • Yetkin-Arik Bahar, Vogels Ilse M. C., Nowak-Sliwinska Patrycja, Weiss Andrea, Houtkooper Riekelt H., van Noorden Cornelis J. F., Klaassen Ingeborg, Schlingemann Reinier O. The role of glycolysis and mitochondrial respiration in the formation and functioning of endothelial tip cells during angiogenesis Scientific reports 2019;9 (1) [PubMed]
  • van Bergen Tine, Etienne Isabelle, Cunningham Fiona, Moons Lieve, Schlingemann Reinier O., Feyen Jean H. M., Stitt Alan W. The role of placental growth factor (PlGF) and its receptor system in retinal vascular diseases Progress in retinal and eye research 2019;69:116-136 [PubMed]

2018

  • Buitendijk Gabriëlle H. S., Schauwvlieghe Ann-Sofie M. E., Vingerling Johannes R., Schlingemann Reinier O., Klaver Caroline C. W. Antiplatelet and anticoagulant drugs do not affect visual outcome in neovascular age-related macular degeneration in the BRAMD trial American journal of ophthalmology 2018;187:130-137 [PubMed]
  • Lorés-Motta Laura, Riaz Moeen, Grunin Michelle, Corominas Jordi, van Asten Freekje, Pauper Marc, Leenders Mathieu, Richardson Andrea J., Muether Philipp, Cree Angela J., Griffiths Helen L., Pham Connie, Belanger Marie-Claude, Meester-Smoor Magda A., Ali Manir, Heid Iris M., Fritsche Lars G., Chakravarthy Usha, Gale Richard, McKibbin Martin, Inglehearn Chris F., Schlingemann Reinier O., Omar Amer, Chen John, Koenekoop Robert K., Fauser Sascha, Guymer Robyn H., Hoyng Carel B., de Jong Eiko K., Lotery Andrew J., Mitchell Paul, den Hollander Anneke I., Baird Paul N., Chowers Itay Association of genetic variants with response to anti-vascular endothelial growth factor therapy in age-related macular degeneration JAMA ophthalmology 2018;136 (8):875-884 [PubMed]
  • Nowak-Sliwinska Patrycja, Alitalo Kari, Allen Elizabeth, Anisimov Andrey, Aplin Alfred C., Auerbach Robert, Augustin Hellmut G., Bates David O., van Beijnum Judy R., Bender R. Hugh F., Bergers Gabriele, Bikfalvi Andreas, Bischoff Joyce, Böck Barbara C., Brooks Peter C., Bussolino Federico, Cakir Bertan, Carmeliet Peter, Castranova Daniel, Cimpean Anca M., Cleaver Ondine, Coukos George, Davis George E., de Palma Michele, Dimberg Anna, Dings Ruud P. M., Djonov Valentin, Dudley Andrew C., Dufton Neil P., Fendt Sarah-Maria, Ferrara Napoleone, Fruttiger Marcus, Fukumura Dai, Ghesquière Bart, Gong Yan, Griffin Robert J., Harris Adrian L., Hughes Christopher C. W., Hultgren Nan W., Iruela-Arispe M. Luisa, Irving Melita, Jain Rakesh K., Kalluri Raghu, Kalucka Joanna, Kerbel Robert S., Kitajewski Jan, Klaassen Ingeborg, Kleinmann Hynda K., Koolwijk Pieter, Kuczynski Elisabeth, Kwak Brenda R., Marien Koen, Melero-Martin Juan M., Munn Lance L., Nicosia Roberto F., Noel Agnes, Nurro Jussi, Olsson Anna-Karin, Petrova Tatiana V., Pietras Kristian, Pili Roberto, Pollard Jeffrey W., Post Mark J., Quax Paul H. A., Rabinovich Gabriel A., Raica Marius, Randi Anna M., Ribatti Domenico, Ruegg Curzio, Schlingemann Reinier O., Schulte-Merker Stefan, Smith Lois E. H., Song Jonathan W., Stacker Steven A., Stalin Jimmy, Stratman Amber N., van de Velde Maureen, van Hinsbergh Victor W. M., Vermeulen Peter B., Waltenberger Johannes, Weinstein Brant M., Xin Hong, Yetkin-Arik Bahar, Yla-Herttuala Seppo, Yoder Mervin C., Griffioen Arjan W. Consensus guidelines for the use and interpretation of angiogenesis assays Angiogenesis 2018;21 (3):425-532 [PubMed]
  • Dallinga Marchien G., Yetkin-Arik Bahar, Kayser Richelle P., Vogels Ilse M. C., Nowak-Sliwinska Patrycja, Griffioen Arjan W., van Noorden Cornelis J. F., Klaassen Ingeborg, Schlingemann Reinier O. IGF2 and IGF1R identified as novel tip cell genes in primary microvascular endothelial cell monolayers Angiogenesis 2018;21 (4):823-836 [PubMed]
  • Demirkaya Nazli In search of retinal biomarkers for HIV related neurodegeneration: The AGEhIV and NOVICE studies 2018. ISBN 9789463610971. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Schlingemann R. O.; Co-supervisors: Verbraak F. D., Wit F. W. N. M.)
  • Ramos de Carvalho J. Emanuel, Verwoert Milan T., Vogels Ilse M. C., Reits Eric A., van Noorden Cornelis J. F., Klaassen Ingeborg, Schlingemann Reinier O. Involvement of the ubiquitin-proteasome system in the expression of extracellular matrix genes in retinal pigment epithelial cells Biochemistry and biophysics reports 2018;13:83-92 [PubMed]
  • Bosma Esmeralda K., van Noorden Cornelis J. F., Klaassen Ingeborg, Schlingemann Reinier O. Microvascular Complications in the Eye: Diabetic Retinopathyin: Diabetic Nephropathy: Pathophysiology and Clinical Aspects. Springer International Publishing; 2018. p. 305-321, ISBN 9783319935201
  • Ramos de Carvalho J. Emanuel, Verwoert Milan T., Vogels Ilse M. C., Schipper-Krom Sabine, van Noorden Cornelis J. F., Reits Eric A., Klaassen Ingeborg, Schlingemann Reinier O. Modulation of the Proteasome Pathway by Nano-Curcumin and Curcumin in Retinal Pigment Epithelial Cells Ophthalmic research 2018;59 (2):98-109 [PubMed]
  • Ramos de Carvalho J. Emanuel Ophthalmic molecular imaging and the role of the proteasome in retinal diseases 2018. ISBN 9789461829160. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Schlingemann R. O., van Noorden C. J. F.; Co-supervisors: Aalders M. C. G., Klaassen I.)
  • Fickweiler Ward, Schauwvlieghe Ann-Sofie M. E., Schlingemann Reinier O., Maria Hooymans Johanna M., Los Leonoor I., Verbraak Frank D. PREDICTIVE VALUE OF OPTICAL COHERENCE TOMOGRAPHIC FEATURES IN THE BEVACIZUMAB AND RANIBIZUMAB IN PATIENTS WITH DIABETIC MACULAR EDEMA (BRDME) STUDY: 812–819 Retina (Philadelphia, Pa.) 2018;38 (4) [PubMed]
  • Ramos de Carvalho J. E., Schlingemann R. O., Oranje M., Bemelman F. J., van Schooneveld M. J. Reversal of threatening blindness after initiation of eculizumab in Purtscher-like retinopathy secondary to atypical hemolytic uremic syndrome International ophthalmology 2018;38 (1):399-407 [PubMed]
  • van der Wijk Anne-Eva, Vogels Ilse M. C., van Veen Henk A., van Noorden Cornelis J. F., Schlingemann Reinier O., Klaassen Ingeborg Spatial and temporal recruitment of the neurovascular unit during development of the mouse blood-retinal barrier Tissue & cell 2018;52:42-50 [PubMed]
  • Bosma Esmeralda K., van Noorden Cornelis J. F., Schlingemann Reinier O., Klaassen Ingeborg The role of plasmalemma vesicle-associated protein in pathological breakdown of blood-brain and blood-retinal barriers: Potential novel therapeutic target for cerebral edema and diabetic macular edema Fluids and barriers of the CNS 2018;15 (1) [PubMed]
  • van der Wijk Anne-Eva You build me up, you break me down: Molecular mechanisms of blood-retinal barrier development and disruption 2018. ISBN 9789461829177. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Schlingemann R. O., van Noorden C. J. F.; Co-supervisor: Klaassen I.)

2017

  • Hendriks Michelle, Verhoeven Virginie J. M., Buitendijk Gabriëlle H. S., Polling Jan Roelof, Meester-Smoor Magda A., Hofman Albert, Kamermans Maarten, Ingeborgh van den Born L., Klaver Caroline C. W., van Huet Ramon A., Klevering B. Jeroen, Bax Nathalie M., Lambertus Stanley, Hoyng Carel B., Oomen Clasien J., van Zelst-Stams Wendy A., Cremers Frans P., Plomp Astrid S., van Schooneveld Mary J., van Genderen Mies M., Schuil José, Boonstra F. Nienke, Schlingemann Reinier O., Bergen Arthur A., Pierrache Laurence, Meester-Smoor Magda, van den Born L. Ingeborgh, Boon Camiel J., Pott Jan W. R., van Leeuwen Redmer, Kroes Hester Y., de Jong-Hesse Yvonne Development of Refractive Errors-What Can We Learn From Inherited Retinal Dystrophies? American journal of ophthalmology 2017;182:81-89 [PubMed]
  • Klaassen Ingeborg, de Vries Ewout W., Vogels Ilse M. C., van Kampen Antoine H. C., Bosscha Machteld I., Steel David H. W., van Noorden Cornelis J. F., Lesnik-Oberstein Sarit Y., Schlingemann Reinier O. Identification of proteins associated with clinical and pathological features of proliferative diabetic retinopathy in vitreous and fibrovascular membranes PLoS ONE 2017;12 (11):e0187304 [PubMed]
  • van der Wijk Anne-Eva, Hughes John M., Klaassen Ingeborg, van Noorden Cornelis J. F., Schlingemann Reinier O. Is leukostasis a crucial step or epiphenomenon in the pathogenesis of diabetic retinopathy? Journal of leukocyte biology 2017;102 (4):993-1001 [PubMed]
  • Lapid-Gortzak Ruth, Traversari Roberto, van der Linden Jan Willem, Lesnik Oberstein Sarit Y., Lapid Oren, Schlingemann Reinier O. Mobile ultra-clean unidirectional airflow screen reduces air contamination in a simulated setting for intra-vitreal injection International ophthalmology 2017;37 (1):131-137 [PubMed]
  • Chung Wing H., van Dijk Elon H. C., Mohabati Danial, Dijkman Greet, Yzer Suzanne, de Jong Eiko K., Fauser Sascha, Schlingemann Reinier O., Hoyng Carel B., Boon Camiel J. F. Neovascular age-related macular degeneration without drusen in the fellow eye: clinical spectrum and therapeutic outcome Clinical ophthalmology (Auckland, N.Z.) 2017;11:63-70 [PubMed]
  • Bennis A., Jacobs J. G., Catsburg L. A. E., ten Brink J. B., Koster C., Schlingemann R. O., van Meurs J., Gorgels T. G. M. F., Moerland P. D., Heine V. M., Bergen A. A. Stem Cell Derived Retinal Pigment Epithelium: The Role of Pigmentation as Maturation Marker and Gene Expression Profile Comparison with Human Endogenous Retinal Pigment Epithelium STEM CELL REVIEWS AND REPORTS 2017;13 (5):659-669 [PubMed]
  • van der Wijk Anne-Eva, Vogels Ilse M. C., van Noorden Cornelis J. F., Klaassen Ingeborg, Schlingemann Reinier O. TNF alpha-Induced Disruption of the Blood-Retinal Barrier In Vitro Is Regulated by Intracellular 3',5'-Cyclic Adenosine Monophosphate Levels Investigative ophthalmology & visual science 2017;58 (9):3496-3505 [PubMed]

2016

  • Fickweiler Ward, Klaassen Ingeborg, Vogels Ilse M. C., Hooymans Johanna M. M., Wolffenbuttel Bruce H. R., Los Leonoor I., Schlingemann Reinier O. Association of Circulating Markers With Outcome Parameters in the Bevacizumab and Ranibizumab in Diabetic Macular Edema Trial Investigative ophthalmology & visual science 2016;57 (14):6234-6241 [PubMed]
  • Siemerink Martin J., Hughes Michael R., Dallinga Marchien G., Gora Tomek, Cait Jessica, Vogels Ilse M. C., Yetin-Arik Bahar, van Noorden Cornelis J. F., Klaassen Ingeborg, McNagny Kelly M., Schlingemann Reinier O. CD34 Promotes Pathological Epi-Retinal Neovascularization in a Mouse Model of Oxygen-Induced Retinopathy PLoS ONE 2016;11 (6):e0157902 [PubMed]
  • Siemerink Martin J., Hughes Michael R., Dallinga Marchien G., Gora Tomek, Cait Jessica, Vogels Ilse M. C., Yetkin-Arik Bahar, van Noorden Cornelis J. F., Klaassen Ingeborg, McNagny Kelly M., Schlingemann Reinier O. CD34 Promotes Pathological Epi-Retinal Neovascularization in a Mouse Model of Oxygen-Induced Retinopathy (vol 11, e0157902, 2016) PLoS ONE 2016;11 (12):e0169061 [PubMed]
  • Bittner Mario, Faes Livia, Boehni Sophie C., Bachmann Lucas M., Schlingemann Reinier O., Schmid Martin K. Colour Doppler analysis of ophthalmic vessels in the diagnosis of carotic artery and retinal vein occlusion, diabetic retinopathy and glaucoma: systematic review of test accuracy studies BMC ophthalmology 2016;16 (1):214 [PubMed]
  • Schauwvlieghe A. M. E., Dijkman G., Hooymans J. M., Verbraak F. D., Hoyng C. B., Dijkgraaf M. G. W., Peto T., Vingerling J. R., Schlingemann R. O. Comparing the Effectiveness of Bevacizumab to Ranibizumab in Patients with Exudative Age-Related Macular Degeneration. The BRAMD Study PLoS ONE 2016;11 (5):e0153052 [PubMed]
  • Palm Margriet M., Dallinga Marchien G., van Dijk Erik, Klaassen Ingeborg, Schlingemann Reinier O., Merks Roeland M. H. Computational Screening of Tip and Stalk Cell Behavior Proposes a Role for Apelin Signaling in Sprout Progression PLoS ONE 2016;11 (11):e0159478 [PubMed]
  • Stehouwer M., Verbraak F. D., Schlingemann R. O., van Leeuwen T. G. Detecting signs of retinal leakage in exudative AMD using Cirrus OCT versus SL SCAN-1, a novel integrated FD-OCT into a common slit lamp Graefe s archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2016;254 (1):37-41 [PubMed]
  • Demirkaya Nazli, Wit Ferdinand W. N. M., van den Berg Thomas J. T. P., Kooij Katherine W., Prins Maria, Schlingemann Reinier O., Abramoff Michael D., Reiss Peter, Verbraak Frank D., van der Valk M., Schouten J. [=Judith], van Zoest R. A., Elsenga B. C., Martens M., Moll S., Berkel J., Totté M., Visser G. R., Kovalev S., Kootstra N. A., van Leeuwen E., Geerlings S. E., Godfried M. H., Goorhuis A., Hovius J. W. R., van der Meer J. T. M., Nellen F. J. B., van der Poll T., Prins J. M., Wiersinga W. J., Postema P. G., Bisschop P. H. L. T., Serlie M. J. M., Dekker E., de Rooij S. E. J. A., Vogt L., Portegies P., Schmand B. A., Geurtsen G. J., van Eck-Smit B. L. F., de Jong M., Richel D. J., Ruhé H. G., Nieuwkerk P. T., van Steenwijk R. P., Majoie C. B. L. M., Caan M. W. A., van Lunsen H. W., van den Born B. J. H., Stroes E. S. G. HIV-Associated Neuroretinal Disorder in Patients With Well-Suppressed HIV-Infection: A Comparative Cohort Study Investigative ophthalmology & visual science 2016;57 (3):1388-1397 [PubMed]
  • Wisniewska-Kruk Joanna, van der Wijk Anne-Eva, van Veen Henk A., Gorgels Theo G. M. F., Vogels Ilse M. C., Versteeg Danielle, van Noorden Cornelis J. F., Schlingemann Reinier O., Klaassen Ingeborg Plasmalemma Vesicle-Associated Protein Has a Key Role in Blood-Retinal Barrier Loss American journal of pathology 2016;186 (4):1044-1054 [PubMed]
  • Sohn Elliott H., van Dijk Hille W., Jiao Chunhua, Kok Pauline H. B., Jeong Woojin, Demirkaya Nazli, Garmager Allison, Wit Ferdinand, Kucukevcilioglu Murat, van Velthoven Mirjam E. J., DeVries J. Hans, Mullins Robert F., Kuehn Markus H., Schlingemann Reinier Otto, Sonka Milan, Verbraak Frank D., Abràmoff Michael David Retinal neurodegeneration may precede microvascular changes characteristic of diabetic retinopathy in diabetes mellitus Proceedings of the National Academy of Sciences of the United States of America 2016;113 (19):E2655-E2664 [PubMed]

2015

  • Wisniewska-Kruk Joanna, Hoeben Kees A., Vogels Ilse M. C., Gaillard Pieter J., van Noorden Cornelis J. F., Schlingemann Reinier O., Klaassen Ingeborg A novel co-culture model of the blood-retinal barrier based on primary retinal endothelial cells, pericytes and astrocytes (vol 96, pg 181, 2012) Experimental eye research 2015;138:167
  • van Asten Freekje, Evers-Birkenkamp Kim U., van Lith-Verhoeven Janneke J. C., de Jong-Hesse Yvonne, Hoppenreijs Vincent P. T., Hommersom Richard F., Scholten Agnes M., Hoyng Carel B., Klaver Johannes H. J., Klaver J. H. J., Hoyng C. B., Raijmakers A. J., van Lith-Verhoeven J. J. C., Rulo A. H. F., Verbraak F. D., Schlingemann R. O., Hommersom C. F., de Jong-Hesse Y., Bosch-Driessen E. H., Smeets M. H., Gonçalves A., Klomp H. J., Hoppenreijs V. P. T., Dito J. J. A prospective, observational, open-label, multicentre study to investigate the daily treatment practice of ranibizumab in patients with neovascular age-related macular degeneration Acta ophthalmologica 2015;93 (2):126-133 [PubMed]
  • Ribeiro Luisa, Bandello Francesco, Tejerina Amparo Navea, Vujosevic Stela, Varano Monica, Egan Catherine, Sivaprasad Sobha, Menon Geeta, Massin Pascale, Verbraak Frank D., Lund-Andersen Henrik, Martinez Jose P., Jürgens Ignasi, Smets Erica, Coriat Caroline, Wiedemann Peter, Ágoas Victor, Querques Giuseppe, Holz Frank G., Nunes Sandrina, Neves Catarina, Cunha-Vaz José, Ribeiro Luísa, Figueira João, Pires Isabel, Leal Sérgio, Simão Silvia, Santos Ana Rita, Simões Isabel, Souied Eric H., Boston Hayley, Degli Esposti Simona, Rocco Vincent, Mathysen Danny G. P., Erginay Ali, Fleckenstein Monika, Cacciamani Andrea, Parravano Mariacristina, Cosimi Pamela, Mourits M., Schlingemann R. O., Wezel M., Jansen-Kok C., Althoff A., de Vries D., Stam M., Jochmann Claudia, Koch Christian, Vollhardt Daniela, Tilgner Christina Characterization of Retinal Disease Progression in a 1-Year Longitudinal Study of Eyes With Mild Nonproliferative Retinopathy in Diabetes Type 2 Investigative ophthalmology & visual science 2015;56 (9):5698-5705 [PubMed]
  • Schauwvlieghe A. M. E., Dijkman G., Hooymans J. M., Verbraak F. D., Hoyng C. B., Dijkgraaf M. G. W., van Leeuwen R., Vingerling J. R., Moll A. C., Schlingemann Reinier O. Comparing the effectiveness and costs of Bevacizumab to Ranibizumab in patients with Diabetic Macular Edema: a randomized clinical trial (the BRDME study) BMC ophthalmology 2015;15 (1):71 [PubMed]
  • Demirkaya Nazli, Wit Ferdinand, Schlingemann Reinier, Verbraak Franciscus Neuroretinal Degeneration in HIV Patients Without Opportunistic Ocular Infections in the cART Era AIDS patient care and STDs 2015;29 (10):519-532 [PubMed]
  • Darma Stanley, Kok Pauline H. B., van den Berg Thomas J. T. P., Abràmoff Michael D., Faber Dirk J., Hulsman Caroline A., Zantvoord Frank, Mourits Maarten P., Schlingemann Reinier O., Verbraak Frank D. Optical density filters modeling media opacities cause decreased SD-OCT retinal layer thickness measurements with inter- and intra-individual variation Acta ophthalmologica 2015;93 (4):355-361 [PubMed]
  • Weiss Andrea, Ding Xianting, van Beijnum Judy R., Wong Ieong, Wong Tse J., Berndsen Robert H., Dormond Olivier, Dallinga Marchien, Shen Li, Schlingemann Reinier O., Pili Roberto, Ho Chih-Ming, Dyson Paul J., van den Bergh Hubert, Griffioen Arjan W., Nowak-Sliwinska Patrycja Rapid optimization of drug combinations for the optimal angiostatic treatment of cancer Angiogenesis 2015;18 (3):233-244 [PubMed]
  • Demirkaya Nazli, Cohen Sophie, Wit Ferdinand W. N. M., Abramoff Michael D., Schlingemann Reinier O., Kuijpers Taco W., Reiss Peter, Pajkrt Dasja, Verbraak Frank D. Retinal Structure and Function in Perinatally HIV-Infected and cART-Treated Children: A Matched Case-Control Study Investigative ophthalmology & visual science 2015;56 (6):3945-3954 [PubMed]
  • Klaassen Ingeborg, van Geest Rob J., Kuiper Esther J., van Noorden Cornelis J. F., Schlingemann Reinier O. The role of CTGF in diabetic retinopathy Experimental eye research 2015;133:37-48 [PubMed]

2014

  • van Geest Rob J., Leeuwis Jan Willem, Dendooven Amélie, Pfister Frederick, Bosch Klazien, Hoeben Kees A., Vogels Ilse M. C., van der Giezen Dionne M., Dietrich Nadine, Hammes Hans-Peter, Goldschmeding Roel, Klaassen Ingeborg, van Noorden Cornelis J. F., Schlingemann Reinier O. Connective tissue growth factor is involved in structural retinal vascular changes in long-term experimental diabetes journal of histochemistry and cytochemistry 2014;62 (2):109-118 [PubMed]
  • Boyer David S., Goldbaum Mauro, Leys Anita M., Starita Carla, Blumenkranz M., Buyse M., Goldberg M., Gragoudas E. S., Miller J., Schwartz S. D., Singerman L., Yannuzzi L., Adamis A. P., Guyer D. R., O'Shaughnessy D., de Gronckel S., Fesneau G., Quinaux E., Tremolet D., Wang K., Brailey A., Finman J., Ting N., Bressler N. M., Bressler S. B., Denblow R., Schein O. D., Seabrook S., Solomon S., Schachat A. P., Philips D., Altaweel M., Davis M. D., Blodi Ba, Danis R. P., Ip M. S., Hiner C., Elledge J., Webster M., Hannan C., Ficken J., Alexander S., Neider M., Wabers H., Vargo P., Lambert E., Kastorff L., Carr A., Shkiele A., Schlingemann R. O. Effect of pegaptanib sodium 0.3 mg intravitreal injections (Macugen) in intraocular pressure: posthoc analysis from VISION study British journal of ophthalmology 2014;98 (11):1543-1546 [PubMed]
  • Schmidt-Erfurth Ursula, Chong Victor, Loewenstein Anat, Larsen Michael, Souied Eric, Schlingemann Reinier, Eldem Bora, Monés Jordi, Richard Gisbert, Bandello Francesco Guidelines for the management of neovascular age-related macular degeneration by the European Society of Retina Specialists (EURETINA) British journal of ophthalmology 2014;98 (9):1144-1167 [PubMed]
  • Wisniewska-Kruk Joanna, Klaassen Ingeborg, Vogels Ilse M. C., Magno Aaron L., Lai Chooi-May, van Noorden Cornelis J. F., Schlingemann Reinier O., Rakoczy Elizabeth P. Molecular analysis of blood-retinal barrier loss in the Akimba mouse, a model of advanced diabetic retinopathy Experimental eye research 2014;122:123-131 [PubMed]
  • Noort Ae R., van Zoest Katinka P. M., Weijers Ester M., Koolwijk Pieter, Maracle Chrissta X., Novack Deborah V., Siemerink Martin J., Schlingemann Reinier O., Tak Paul P., Tas Sander W. NF-κB-inducing kinase is a key regulator of inflammation-induced and tumour-associated angiogenesis Journal of pathology 2014;234 (3):375-385 [PubMed]
  • Kok Pauline Herma Berthe Optical coherence tomography beware of optical illusions 2014. 136p. ISBN 9789461824820. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Mourits M. P., Schlingemann R. O.; Co-supervisors: Verbraak F. D., van den Berg T. J. T. P.)
  • van Zijderveld Rogier, Ince Can, Schlingemann Reinier O. Orthogonal polarization spectral imaging of conjunctival microcirculation Graefe s archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2014;252 (5):773-779 [PubMed]
  • Wisniewska-Kruk Joanna PLVAP in diabetic retinopathy: a gatekeeper of angiogenesis and vascular permeability 2014. 173p. ISBN 9789461824936. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Schlingemann R. O., van Noorden C. J. F.; Co-supervisor: Klaassen I.)
  • Ramos de Carvalho J. Emanuel, Verbraak Frank D., Aalders Maurice C., van Noorden Cornelis J., Schlingemann Reinier O. Recent advances in ophthalmic molecular imaging Survey of ophthalmology 2014;59 (4):393-413 [PubMed]
  • van Dijk Hille Willemijn Shedding new light on diabetic retinopathy with optical coherence tomography 2014. 143p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Schlingemann R. O.; Co-supervisors: Verbraak F. D., Abràmoff M. D.)
  • van der Meulen Ivanka J. E. Straylight in anterior segment disorders of the eye 2014. 263p. ISBN 9789461919915. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Mourits M. P., Schlingemann R. O.; Co-supervisor: van den Berg T. J. T. P.)
  • van Huet Ramon A. C., Oomen Clasien J., Plomp Astrid S., van Genderen Maria M., Klevering B. Jeroen, Schlingemann Reinier O., Klaver Caroline C. W., van den Born L. Ingeborgh, Cremers Frans P. M., Bax Nathalie M., Hoyng Carel B., van Zelst-Stams Wendy A., Bergen Arthur A. B., Schuil José, van Schooneveld Mary J., Pierrache Laurence, Meester-Smoor Magda A., Boon Camiel J. F., Pott Jan Willem R., van Leeuwen Redmer, Kroes Hester Y., Boonstra F. Nienke The RD5000 Database: Facilitating Clinical, Genetic, and Therapeutic Studies on Inherited Retinal Diseases Investigative ophthalmology & visual science 2014;55 (11):7355-7360 [PubMed]
  • Schmidt-Erfurth Ursula, Lang Gabriele E., Holz Frank G., Schlingemann Reinier O., Lanzetta Paolo, Massin Pascale, Gerstner Ortrud, Bouazza Abdelkader Si, Shen Haige, Osborne Aaron, Mitchell Paul, Papp Andras, Seres Andras, Berta Andras, Pesztenlehrer Norbert, Weber Michel, Creuzot- Garcher Catherine, Emmerich Karl-Heinz, Engelmann Katrin, Hansen Lutz, Kellner Ulrich, Kirchhof Bernd, Mohr Andreas, Spital Georg, Wiedemann Peter, Schrage Norbert, Menchini Ugo, Balestrazzi Emilio, Noci Nicola Delle, Ciriano J. P. Martinez, Kleverling Bert Jeroen, van Calster Joachim, Devriendt Marlene, Kurz-Levin Malaika, Jürgens Inga, Schneider Ulrike, Garweg Justus, Tappeiner Christoph, Gerding Heinrich, Kloos Patrik, Eldem Bora, Sobaci Gungor, Kapran Ziya, Ergin Mehmet, Hasanreisoglu Berati, Arumi Josep Garcia, Ulla Francisco Gomez, Imaz Ramon Torres, Cervera Enrique, Civera Alfredo Adan Three-year outcomes of individualized ranibizumab treatment in patients with diabetic macular edema: the RESTORE extension study Ophthalmology 2014;121 (5):1045-1053 [PubMed]

2013

  • Siemerink Martin J. Angiogenic tip cells endothelial cell structures 2013. 154p. ISBN 9789461085559. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Schlingemann R. O., van Noorden C. J. F.; Co-supervisor: Klaassen I.)
  • Ramos de Carvalho J. Emanuel, Klaassen Ingeborg, Vogels Ilse M. C., Schipper-Krom Sabine, van Noorden Cornelis J. F., Reits Eric, Gorgels Theo G. M. F., Bergen Arthur A. B., Schlingemann Reinier O. Complement factor C3a alters proteasome function in human RPE cells and in an animal model of age-related RPE degeneration Investigative ophthalmology & visual science 2013;54 (10):6489-6501 [PubMed]
  • Demirkaya Nazli, van Dijk Hille W., van Schuppen Sanne M., Abràmoff Michael D., Garvin Mona K., Sonka Milan, Schlingemann Reinier O., Verbraak Frank D. Effect of age on individual retinal layer thickness in normal eyes as measured with spectral-domain optical coherence tomography Investigative ophthalmology & visual science 2013;54 (7):4934-4940 [PubMed]
  • Siemerink Martin J., Klaassen Ingeborg, van Noorden Cornelis J. F., Schlingemann Reinier O. Endothelial Tip Cells in Ocular Angiogenesis: Potential Target for Anti-Angiogenesis Therapy journal of histochemistry and cytochemistry 2013;61 (2):101-115 [PubMed]
  • Klaassen Ingeborg, van Noorden Cornelis J. F., Schlingemann Reinier O. Molecular basis of the inner blood-retinal barrier and its breakdown in diabetic macular edema and other pathological conditions Progress in retinal and eye research 2013;34:19-48 [PubMed]
  • Mitchell Paul, Bressler Neil, Tolley Keith, Gallagher Meghan, Petrillo Jennifer, Ferreira Alberto, Wood Robert, Bandello Francesco, Adan Civera Alfredo, Akkin Cezmi, Bailey Clare, Balestrazzi Emilio, Beare Nicholas, Berecki Arpad, Berta Andras, Boyd Shelley, Brazitikos Periklis, Cervera Enrique, Chen John, Creuzot-Garcher Catherine, Delle Noci Nicola, Devriendt Marlene, Dimitrakos Stavros, Eldem Bora, Emmerich Karl-Heinz, Engelmann Katrin, Ergin Mehmet, Fleischhauer Johannes, Garcia-Arumi Josep, Garweg Justus, Gerding Heinrich, Gillies Mark, Gomez Ulla Francisco, Gonder John, Grisanti Salvatore, Hansen Lutz L., Hasanreisoglu Berati, Hoeh Helmut, Holz Frank G., Ioaanis Vergados, Joussen Antonia, Kabanarou Stamatina, Kampik Anselm, Kapran Ziya, Kellner Ulrich, Kerényi Agnes, Kertes Peter, Kirchhof Bernd, Klevering B. J., Schlingemann R. O. Patient-reported visual function outcomes improve after ranibizumab treatment in patients with vision impairment due to diabetic macular edema: randomized clinical trial JAMA ophthalmology 2013;131 (10):1339-1347 [PubMed]
  • Pennock Steven, Kim David, Mukai Shizuo, Kuhnle Matthew, Chun Dal W., Matsubara Joanne, Cui Jing, Ma Patrick, Maberley David, Samad Arif, van Geest Robert J., Oberstein Sarit L., Schlingemann Reinier O., Kazlauskas Andrius Ranibizumab is a potential prophylaxis for proliferative vitreoretinopathy, a nonangiogenic blinding disease American journal of pathology 2013;182 (5):1659-1670 [PubMed]
  • Kok Pauline H. B., van Dijk Hille W., Stehouwer Marilette, van den Berg Thomas J. T. P., Schlingemann R. O., Verbraak Frank D. Standardised disturbance of the optical coherence tomography signal has varying effects on the scan quality assessment when comparing four devices British journal of ophthalmology 2013;97 (11):1484-1485 [PubMed]
  • Silva Rufino, Axer-Siegel Ruth, Eldem Bora, Guymer Robyn, Kirchhof Bernd, Papp Andras, Seres Andras, Gekkieva Margarita, Nieweg Annette, Pilz Stefan, Leys Anita, Rakic Jean-Marie, Postelmans Laurence, Facsko Andrea, Falcão Reis F., Schlingemann R. O., Hoyng C. P., Casaroli Ricardo, Mateo Carlos, Tejerina Amparo Navea, Cervera Enrique, Moreno Jose Ruiz, Lopez Juan Donate, Ulla Francisco Gomez, Armada Felix, Yang Yit-Chuijn, Bailey Clare, Lotery Andrew, Gibson Jon, Wiedemann Peter, Bartz-Schmidt Karl-Ulrich, Engelmann Katrin, Holz Frank, Kampik Anselm, Kellner Ulrich, Lemmen Klaus, Mennel Stefan, Mohr Andreas, Roider Johann, Guthoff Rainer, Foerster Michael, Moisseiev Joseph, Goldstein Michaela, Ozmert Emin The SECURE study: long-term safety of ranibizumab 0.5 mg in neovascular age-related macular degeneration Ophthalmology 2013;120 (1):130-139 [PubMed]
  • Lang Gabriele E., Berta András, Eldem Bora M., Simader Christian, Sharp Dianne, Holz Frank G., Sutter Florian, Gerstner Ortrud, Mitchell Paul, Adan Civera A., Bailey C., Balestrazzi E., Boyd S., Cervera E., Creuzot-Garcher C., Delle Noci N., Devriendt M., Emmerich K.-H., Ergin M., Garcia-Arumi J., Garweg J., Gerding H., Gillies M., Gonder J., Hansen L., Hasanreisoglu B., Jürgens I., Kapran Z., Kellner U., Kerényi A., Kertes P., Kirchhof B., Kleverling B. J., Kloos P., Kurz-Levin M., Lim L., Lanzetta P., Maberley D., Massin P., Martinez Ciriano J. P., Menchini U., Mohr A., Olivier S., Papp A., Pesztenlehrer N., Ruiz Moreno J., Sborgia C., Schlingemann R. O., Schneider U., Schrage N. Two-year safety and efficacy of ranibizumab 0.5 mg in diabetic macular edema: interim analysis of the RESTORE extension study Ophthalmology 2013;120 (10):2004-2012 [PubMed]
  • van Dijk Hille W., Verbraak Frank D., Kok Pauline H. B., Oberstein Sarit Y. L., Schlingemann Reinier O., Russell Stephen R., Abràmoff Michael D. Variability in photocoagulation treatment of diabetic macular oedema Acta ophthalmologica 2013;91 (8):722-727 [PubMed]
  • Schlingemann Reinier O., van Noorden Cornelis J. F., Diekman Mattheus J. M., Tiller Anna, Meijers Joost C. M., Koolwijk Pieter, Wiersinga Wilmar M. VEGF levels in plasma in relation to platelet activation, glycemic control, and microvascular complications in type 1 diabetes Diabetes care 2013;36 (6):1629-1634 [PubMed]
  • van Geest Rob J., Klaassen Ingeborg, Lesnik-Oberstein Sarit Y., Tan H. Stevie, Mura Marco, Goldschmeding Roel, van Noorden Cornelis J. F., Schlingemann Reinier O. Vitreous TIMP-1 levels associate with neovascularization and TGF-beta 2 levels but not with fibrosis in the clinical course of proliferative diabetic retinopathy Journal of cell communication and signaling 2013;7 (1):1-9 [PubMed]

2012

  • Wisniewska-Kruk Joanna, Hoeben Kees A., Vogels Ilse M. C., Gaillard Pieter J., van Noorden Cornelis J. F., Schlingemann Reinier O., Klaassen Ingeborg A novel co-culture model of the blood-retinal barrier based on primary retinal endothelial cells, pericytes and astrocytes Experimental eye research 2012;96 (1):181-190 [PubMed]
  • van Geest Rob J., Lesnik-Oberstein Sarit Y., Tan H. Stevie, Mura Marco, Goldschmeding Roel, van Noorden Cornelis J. F., Klaassen Ingeborg, Schlingemann Reinier O. A shift in the balance of vascular endothelial growth factor and connective tissue growth factor by bevacizumab causes the angiofibrotic switch in proliferative diabetic retinopathy British journal of ophthalmology 2012;96 (4):587-590 [PubMed]
  • Siemerink Martin J., Klaassen Ingeborg, Vogels Ilse M. C., Griffioen Arjan W., van Noorden Cornelis J. F., Schlingemann Reinier O. CD34 marks angiogenic tip cells in human vascular endothelial cell cultures Angiogenesis 2012;15 (1):151-163 [PubMed]
  • van Dijk Hille W., Verbraak Frank D., Kok Pauline H. B., Stehouwer Marilette, Garvin Mona K., Sonka Milan, DeVries J. Hans, Schlingemann Reinier O., Abràmoff Michael D. Early Neurodegeneration in the Retina of Type 2 Diabetic Patients Investigative ophthalmology & visual science 2012;53 (6):2715-2719 [PubMed]
  • Dell'Omo Roberto, Tan H. Stevie, Schlingemann Reinier O., Bijl Heico M., Lesnik Oberstein Sarit Y., Barca Francesco, Mura Marco Evolution of Outer Retinal Folds Occurring after Vitrectomy for Retinal Detachment Repair Investigative ophthalmology & visual science 2012;53 (13):7928-7935 [PubMed]
  • Falke Lucas L., Dendooven Amélie, Leeuwis Jan Willem, Nguyen Tri Q., van Geest Rob J., van der Giezen Dionne M., Broekhuizen Roel, Lyons Karen, Stoop Reinout, Kemperman Hans, Schlingemann Reinier, Joles Jaap A., Goldschmeding Roel Hemizygous deletion of CTGF/CCN2 does not suffice to prevent fibrosis of the severely injured kidney Matrix biology 2012;31 (7-8):421-431 [PubMed]
  • Reuwer Anne Q., Sondermeijer Brigitte M., Battjes Suzanne, van Zijderveld Rogier, Stuijver Danka J. F., Bisschop Peter H., Twickler Marcel Th B., Meijers Joost C. M., Schlingemann Reinier O., Stroes Erik S. Microcirculation and atherothrombotic parameters in prolactinoma patients: a pilot study Pituitary 2012;15 (4):472-481 [PubMed]
  • Bandello F., Cunha-Vaz J., Chong N. V., Lang G. E., Massin P., Mitchell P., Porta M., Prünte C., Schlingemann R., Schmidt-Erfurth U. New approaches for the treatment of diabetic macular oedema: recommendations by an expert panel Eye (London, England) 2012;26 (4):485-493 [PubMed]
  • Berner A. K., Brouwers O., Pringle R., Klaassen I., Colhoun L., McVicar C., Brockbank S., Curry J. W., Miyata T., Brownlee M., Schlingemann R. O., Schalkwijk C., Stitt A. W. Protection against methylglyoxal-derived AGEs by regulation of glyoxalase 1 prevents retinal neuroglial and vasodegenerative pathology Diabetologia 2012;55 (3):845-854 [PubMed]
  • van der Meulen Ivanka J. E., Gjertsen Jennifer, Kruijt Bastiaan, Witmer Jan Peter, Rulo Alexander, Schlingemann Reinier O., van den Berg Thomas J. T. P. Straylight measurements as an indication for cataract surgery Journal of cataract and refractive surgery 2012;38 (5):840-848 [PubMed]
  • van Geest Robert Jan TGF-beta and CTGF: pro-fibrotic factors in diabetic retinopathy 2012. 123p. ISBN 9789461821669. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van Noorden C. J. F., Schlingemann R. O.; Co-supervisors: Klaassen I., Mourits M. P.)
  • van Geest R. J., Kuiper E. J., Klaassen I., van Noorden C. J. F., Schlingemann R. O. The Role of CTGF in Diabetic Retinopathyin: Joyce Tombran-Tink, Colin J. Barnstable, Thomas W. Gardner, editors. Visual Dysfunction in Diabetes : The Science of Patient Impairment and Health Care. Berlin: Springer; 2012. p. 261-285, ISBN 9781607611493; 9781607611509

2011

  • van Dijk Hille W., Verbraak Frank D., Stehouwer Marilette, Kok Pauline H. B., Garvin Mona K., Sonka Milan, DeVries J. Hans, Schlingemann Reinier O., Abràmoff Michael D. Association of visual function and ganglion cell layer thickness in patients with diabetes mellitus type 1 and no or minimal diabetic retinopathy Vision research 2011;51 (2):224-228 [PubMed]
  • Schmidt-Erfurth Ursula, Eldem Bora, Guymer Robyn, Korobelnik Jean-Franc̦ois, Schlingemann Reinier O., Axer-Siegel Ruth, Wiedemann Peter, Simader Christian, Gekkieva Margarita, Weichselberger Andreas Efficacy and Safety of Monthly versus Quarterly Ranibizumab Treatment in Neovascular Age-related Macular Degeneration: The EXCITE Study Ophthalmology 2011;118 (5):831-839 [PubMed]
  • Holz Frank G., Amoaku Winfried, Donate Juan, Guymer Robyn H., Kellner Ulrich, Schlingemann Reinier O., Weichselberger Andreas, Staurenghi Giovanni Safety and Efficacy of a Flexible Dosing Regimen of Ranibizumab in Neovascular Age-Related Macular Degeneration: The SUSTAIN Study Ophthalmology 2011;118 (4):663-671 [PubMed]
  • Mitchell Paul, Bandello Francesco, Schmidt-Erfurth Ursula, Lang Gabriele E., Massin Pascale, Schlingemann Reinier O., Sutter Florian, Simader Christian, Burian Gabriela, Gerstner Ortrud, Weichselberger Andreas The RESTORE Study Ranibizumab Monotherapy or Combined with Laser versus Laser Monotherapy for Diabetic Macular Edema Ophthalmology 2011;118 (4):615-625 [PubMed]
  • Niers Tatjana M. H., Richel Dick J., Meijers Joost C. M., Schlingemann Reinier O. Vascular endothelial growth factor in the circulation in cancer patients may not be a relevant biomarker PLoS ONE 2011;6 (5):e19873 [PubMed]
  • Gorgels Theo G. M. F., Waarsing Jan H., Herfs Marjolein, Versteeg Daniëlle, Schoensiegel Frank, Sato Toshiro, Schlingemann Reinier O., Ivandic Boris, Vermeer Cees, Schurgers Leon J., Bergen Arthur A. B. Vitamin K supplementation increases vitamin K tissue levels but fails to counteract ectopic calcification in a mouse model for pseudoxanthoma elasticum Journal of molecular medicine (Berlin, Germany) 2011;89 (11):1125-1135 [PubMed]

2010

  • Hughes John M., Groot Arjan J., van der Groep Petra, Sersansie René, Vooijs Marc, van Diest Paul J., van Noorden Cornelis J. F., Schlingemann Reinier O., Klaassen Ingeborg Active HIF-1 in the Normal Human Retina journal of histochemistry and cytochemistry 2010;58 (3):247-254 [PubMed]
  • Missotten Guy S., Schlingemann Reinier O., Jager Martine J. Angiogenesis and Vascular Endothelial Growth Factors in Intraocular Tumors Developments in ophthalmology 2010;46:123-132 [PubMed]
  • van Dijk Hille W., Verbraak Frank D., Kok Pauline H. B., Garvin Mona K., Sonka Milan, Lee Kyungmoo, DeVries J. Hans, Michels Robert P. J., van Velthoven Mirjam E. J., Schlingemann Reinier O., Abràmoff Michael D. Decreased retinal ganglion cell layer thickness in patients with type 1 diabetes Investigative ophthalmology & visual science 2010;51 (7):3660-3665 [PubMed]
  • van Geest Rob J., Klaassen Ingeborg, Vogels Ilse M. C., van Noorden Cornelis J. F., Schlingemann Reinier O. Differential TGF-beta Signaling in Retinal Vascular Cells: A Role in Diabetic Retinopathy? Investigative ophthalmology & visual science 2010;51 (4):1857-1865 [PubMed]
  • Broekhuizen L. N., Lemkes B. A., Mooij H. L., Meuwese M. C., Verberne H., Holleman F., Schlingemann R. O., Nieuwdorp M., Stroes E. S. G., Vink H. Effect of sulodexide on endothelial glycocalyx and vascular permeability in patients with type 2 diabetes mellitus Diabetologia 2010;53 (12):2646-2655 [PubMed]
  • McWilliams Hughes John Endothelial dysfunction in experimental models of preclinical diabetic retinopathy 2010. 151p. ISBN 9789490371111. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van Noorden C. J. F., Schlingemann R. O.; Co-supervisor: Klaassen I.)
  • Siemerink Martin J., Augustin Albert J., Schlingemann Reinier O. Mechanisms of ocular angiogenesis and its molecular mediators Developments in ophthalmology 2010;46:4-20 [PubMed]
  • van der Meulen Ivanka J. E., Engelbrecht Leonore A., van Vliet Johannes M. J., Lapid-Gortzak Ruth, Nieuwendaal Carla P., Mourits Maarten P., Schlingemann Reinier O., van den Berg Thomas J. T. P. Straylight Measurements in Contact Lens Wear Cornea 2010;29 (5):516-522 [PubMed]

2009

  • Klaassen Ingeborg, Hughes John M., Vogels Ilse M. C., Schalkwijk Casper G., van Noorden Cornelis J. F., Schlingemann Reinier O. Altered expression of genes related to blood-retina barrier disruption in streptozotocin-induced diabetes Experimental eye research 2009;89 (1):4-15 [PubMed]
  • Schlingemann R. O. Oogafwijkingen bij diabetes op oudere leeftijd: lang niet altijd retinopathie, maar vaak maculadegeneratie DiabeteSpecialist 2009;2009 (8):18-19
  • Schlingemann R. O. Oogproblemen bij diabetes Patient care 2009;2009 (36):5-8
  • van Dijk Hille W., Kok Pauline H. B., Garvin Mona, Sonka Milan, DeVries J. Hans, Michels Robert P., van Velthoven Mirjam E. J., Schlingemann Reinier O., Verbraak Frank D., Abramoff Michael David Selective Loss of Inner Retinal Layer Thickness in Type 1 Diabetic Patients with Minimal Diabetic Retinopathy Investigative ophthalmology & visual science 2009;50 (7):3404-3409 [PubMed]
  • Schlingemann R. O., Witmer A. N. Treatment of retinal diseases with VEGF antagonists Progress in brain research 2009;175:253-267 [PubMed]

2008

  • Kuiper Esther J., van Zijderveld Rogier, Roestenberg Peggy, Lyons Karen M., Goldschmeding Roel, Klaassen Ingeborg, van Noorden Cornelis J. F., Schlingemann Reinier O. Connective tissue growth factor is necessary for retinal capillary basal lamina thickening in diabetic mice journal of histochemistry and cytochemistry 2008;56 (8):785-792 [PubMed]
  • Santiago Ana R., Hughes John M., Kamphuis Willem, Schlingemann Reinier O., Ambrósio António F. Diabetes changes ionotropic glutamate receptor subunit expression level in the human retina Brain research 2008;1198:153-159 [PubMed]
  • Borst Piet, van de Wetering Koen, Schlingemann Reinier Does the absence of ABCC6 (multidrug resistance protein 6) in patients with Pseudoxanthoma elasticum prevent the liver from providing sufficient vitamin K to the periphery? Cell cycle (Georgetown, Tex.) 2008;7 (11):1575-1579 [PubMed]
  • Walland S. C., Schlingemann R. O. Nieuwe geneesmiddelen voor maculadegeneratiein: A. Anonymous, editors. Geneesmiddelenbulletin. S.l.: s.n.; 2008. p. 31
  • Kuiper Esther J., van Nieuwenhoven Frans A., de Smet Marc D., van Meurs Jan C., Tanck Michael W., Oliver Noelynn, Klaassen Ingeborg, van Noorden Cornelis J. F., Goldschmeding Roel, Schlingemann Reinier O. The Angio-Fibrotic Switch of VEGF and CTGF in Proliferative Diabetic Retinopathy PLoS ONE 2008;3 (7):e2675 [PubMed]

2007

  • Hughes J. M., Kuiper E. J., Klaassen I., Canning P., Stitt A. W., van Bezu J., Schalkwijk C. G., van Noorden C. J. F., Schlingemann R. O. Advanced glycation end products cause increased CCN family and extracellular matrix gene expression in the diabetic rodent retina Diabetologia 2007;50 (5):1089-1098 [PubMed]
  • Kuiper Esther J., Roestenberg Peggy, Ehlken Christoph, Lambert Vincent, van Treslong-de Groot Henny Bloys, Lyons Karen M., Agostini Hans-Jürgen T., Rakic Jean-Marie, Klaassen Ingeborg, van Noorden Cornelis J. F., Goldschmeding Roel, Schlingemann Reinier O. Angiogenesis is not impaired in connective tissue growth factor (CTGF) knock-out mice journal of histochemistry and cytochemistry 2007;55 (11):1139-1147 [PubMed]
  • Biallosterski Carine, van Velthoven Mirjam E. J., Michels Robert P. J., Schlingemann Reinier O., DeVries J. Hans, Verbraak Frank D. Decreased optical coherence tomography-measured pericentral retinal thickness in patients with diabetes mellitus type 1 with minimal diabetic retinopathy British journal of ophthalmology 2007;91 (9):1135-1138 [PubMed]
  • Schlingemann R. O., van der Meulen I. J. E., Nieuwendaal C. P. De standaard 'Het rode oog' (eerste herziening) van het Nederlands Huisartsen Genootschap; reactie vanuit de oogheelkunde Nederlands tijdschrift voor geneeskunde 2007;151 (22):1219-1221 [PubMed]
  • Kuiper Esther J., Hughes John M., van Geest Rob J., Vogels Ilse M. C., Goldschmeding Roel, van Noorden Cornelis J. F., Schlingemann Reinier O., Klaassen Ingeborg Effect of VEGF-A on expression of profibrotic growth factor and extracellular matrix genes in the retina Investigative ophthalmology & visual science 2007;48 (9):4267-4276 [PubMed]
  • van Weel Vincent, Seghers Leonard, de Vries Margreet R., Kuiper Esther J., Schlingemann Reinier O., Bajema Ingeborg M., Lindeman Jan H. N., Diemen Pien M. Delis-van, van Hinsbergh Victor W. M., van Bockel J. Hajo, Quax Paul H. A. Expression of vascular endothelial growth factor, stromal cell-derived factor-1, and CXCR4 in human limb muscle with acute and chronic ischemia Arteriosclerosis, thrombosis, and vascular biology 2007;27 (6):1426-1432 [PubMed]
  • Schmidt-Erfurth Ursula M., Richard Gisbert, Augustin Albert, Aylward William G., Bandello Francesco, Corcòstegui Borja, Cunha-Vaz José, Gaudric Alain, Leys Anita, Schlingemann Rainier O. Guidance for the treatment of neovascular age-related macular degeneration Acta ophthalmologica Scandinavica 2007;85 (5):486-494 [PubMed]
  • Hartstra W. W., Holleman F., Hoekstra J. B. L., Schlingemann R. O. Screening op diabetische retinopathie Nederlands tijdschrift voor geneeskunde 2007;151 (4):228-233 [PubMed]
  • Jaalouk Diana E., Ozawa Nfichael G., Sun Jessica, Lahdenranta Johanna, Schlingemann Reinier O., Pasqualini Renata, Arap Wadih The original Pathologische Anatomie Leiden-Endothelium monoclonal antibody recognizes a vascular endothelial growth factor binding site within neuropilin-1 Cancer research 2007;67 (20):9623-9629 [PubMed]

2006

  • van Velthoven M. E. J., de Smet M. D., Schlingemann R. O., Magnani M., Verbraak F. D. Added value of OCT in evaluating the presence of leakage in patients with age-related macular degeneration treated with PDT Graefe s archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2006;244 (9):1119-1123 [PubMed]
  • Kuiper Esther J., de Smet Marc D., van Meurs Jan C., Tan H. Stevie, Tanck Michael W. T., Oliver Noelynn, van Nieuwenhoven Frans A., Goldschmeding Roel, Schlingemann Reinier O. Association of connective tissue growth factor with fibrosis in vitreoretinal disorders in the human eye Archives of ophthalmology 2006;124 (10):1457-1462 [PubMed]
  • van Velthoven Mirjam E. J., Ongkosuwito Jenny V., Verbraak Frank D., Schlingemann Reinier O., de Smet Marc D. Combined en-face optical coherence tomography and confocal ophthalmoscopy findings in active multifocal and serpiginous chorioretinitis American journal of ophthalmology 2006;141 (5):972-975 [PubMed]
  • D'Amico Donald J., Masonson H. N., Patel Manju, Adamis A. P., Cunningham E. T., Guyer D. R., Katz B., Schlingemann R. O. Pegaptanib sodium for neovascular age-related macular degeneration: two-year safety results of the two prospective, multicenter, controlled clinical trials Ophthalmology 2006;113 (6):992-1001.e6 [PubMed]
  • Verbraak F. D., Schlingemann R. O., de Smet M. D., Keunen J. E. E. Single spot PDT in patients with circumscribed choroidal haemangioma and near normal visual acuity Graefe s archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2006;244 (9):1178-1182 [PubMed]
  • Kuiper E. J. The role of CTFG in diabetic retinopathy 2006. 197p. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van Noorden C. J. F., de Smet M. D.; Co-supervisors: Schlingemann R. O., Goldschmeding R.)
  • Missotten Guy S. O., Notting Irene C., Schlingemann Reinier O., Zijlmans Henry J., Lau Chun, Eilers Paul H. C., Keunen Jan E. E., Jager Martine J. Vascular endothelial growth factor a in eyes with uveal melanoma Archives of ophthalmology 2006;124 (10):1428-1434 [PubMed]
  • Chakravarthy U., Adamis A. P., Cunningham E. T., Goldbaum M., Guyer D. R., Katz B., Patel Manju, Schlingemann R. O. Year 2 efficacy results of 2 randomized controlled clinical trials of pegaptanib for neovascular age-related macular degeneration Ophthalmology 2006;113 (9):1508.e1-1508.25 [PubMed]

2005

  • Gonzales Christine R., Schlingemann R. O. Enhanced efficacy associated with early treatment of neovascular age-related macular degeneration with pegaptanib sodium: an exploratory analysis Retina (Philadelphia, Pa.) 2005;25 (7):815-827 [PubMed]
  • van Velthoven M. E. J., Verbraak F. D., Garcia P. M., Schlingemann R. O., Rosen R. B., de Smet M. D. Evaluation of central serous retinopathy with en face optical coherence tomography British journal of ophthalmology 2005;89 (11):1483-1488 [PubMed]
  • Arden G. B., Sidman R. L., Arap W., Schlingemann R. O. Spare the rod and spoil the eye British journal of ophthalmology 2005;89 (6):764-769 [PubMed]
  • van Royen Niels, Schirmer Stephan H., Atasever Bektas, Behrens Casper Y. H., Ubbink Dirk, Buschmann Eva E., Voskuil Michiel, Bot Pieter, Hoefer Imo, Schlingemann Reinier O., Biemond Bart J., Tijssen J. G., Bode Christoph, Schaper Wolfgang, Oskam Jacques, Legemate Dink A., Piek Jan J., Buschmann Ivo START trial - A pilot study on STimulation of ARTeriogenesis using subcutaneous application of granulocyte-macrophage colony-stimulating factor as a new treatment for peripheral vascular disease Circulation 2005;112 (7):1040-1046 [PubMed]
  • Dallinga Marchien G., Boas Sonja E. M., Klaassen Ingeborg, Merks Roeland H. M., van Noorden Cornelis J. F., Schlingemann Reinier O. Tip Cells in Angiogenesisin: N. N., editors. Encyclopedia of life sciences (eLS). Chichester: John Wiley & Sons Ltd; 2005. p. a0025977
  • van den Born Bert-Jan H., Hulsman Caroline A. A., Hoekstra Joost B. L., Schlingemann Reinier O., van Montfrans Gert A. Value of routine funduscopy in patients with hypertension: systematic review BMJ (Clinical research ed.) 2005;331 (7508):73-76A [PubMed]

2004

  • Marchiò Serena, Lahdenranta Johanna, Schlingemann Reinier O., Valdembri Donatella, Wesseling Pieter, Arap Marco A., Hajitou Amin, Ozawa Michael G., Trepel Martin, Giordano Ricardo J., Nanus David M., Dijkman Henri B. P. M., Oosterwijk Egbert, Sidman Richard L., Cooper Max D., Bussolino Federico, Pasqualini Renata, Arap Wadih Aminopeptidase A is a functional target in angiogenic blood vessels Cancer cell 2004;5 (2):151-162 [PubMed]
  • Verheul H. M. W., Voest E. E., Schlingemann R. O. Are tumours angiogenesis-dependent? Journal of pathology 2004;202 (1):5-13 [PubMed]
  • Roestenberg Peggy, van Nieuwenhoven Frans A., Wieten Lotte, Boer Peter, Diekman Theo, Tiller Anna M., Wiersinga Wilmar M., Oliver Noelynn, Usinger William, Weitz Stephen, Schlingemann Reinier O., Goldschmeding Roel Connective tissue growth factor is increased in plasma of type 1 diabetic patients with nephropathy Diabetes care 2004;27 (5):1164-1170 [PubMed]
  • Kuiper E. J., Witmer A. N., Klaassen I., Oliver N., Goldschmeding R., Schlingemann R. O. Differential expression of connective tissue growth factor in microglia and pericytes in the human diabetic retina British journal of ophthalmology 2004;88 (8):1082-1087 [PubMed]
  • Spliet W. G. M., Aronica E., Ramkema M., Witmer A. N., Schlingemann R. O., de Jong J. M. B. V., Troost D. Immunohistochemical localization of vascular endothelial growth factor receptors-1, -2 and -3 in human spinal cord: altered expression in amyotrophic lateral sclerosis Neuropathology and applied neurobiology 2004;30 (4):351-359 [PubMed]
  • Witmer Antonella N., van Blijswijk Bart C., van Noorden Cornelis J. F., Vrensen Gijs F. J. M., Schlingemann Reinier O. In vivo angiogenic phenotype of endothelial cells and pericytes induced by vascular endothelial growth factor-A journal of histochemistry and cytochemistry 2004;52 (1):39-52 [PubMed]
  • Wakelkamp Iris M. M. J., Tan Hendra, Saeed Peerooz, Schlingemann Reinier O., Verbraak Frank D., Blank Leo E. C. M., Prummel Mark F., Wiersinga Wilmar M. Orbital irradiation for Graves' ophthalmopathy - Is it safe? A long-term follow-up study Ophthalmology 2004;111 (8):1557-1562 [PubMed]
  • Gragoudas Evangelos S., Adamis Anthony P., Cunningham Emmett T., Feinsod Matthew, Guyer David R., Schlingemann R. O. Pegaptanib for neovascular age-related macular degeneration New England journal of medicine 2004;351 (27):2805-2816 [PubMed]
  • Schlingemann Reinier O. Role of growth factors and the wound healing response in age-related macular degeneration Graefe s archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2004;242 (1):91-101 [PubMed]
  • van den Born B. J., Schlingemann R. O., Hoekstra J. B., van Montfrans G. A. Routinematig onderzoek van de retina bij patiënten met hypertensie niet zinvol Nederlands tijdschrift voor geneeskunde 2004;148 (10):464-468 [PubMed]
  • van Weel Vincent, Deckers Martine M. L., Grimbergen Jos M., van Leuven Kees J. M., Lardenoye JanWillem H. P., Schlingemann Reinier O., van Nieuw Amerongen Geerten P., van Bockel J. Hajo, van Hinsbergh Victor W. M., Quax Paul H. A. Vascular endothelial growth factor overexpression in ischemic skeletal muscle enhances myoglobin expression in vivo Circulation research 2004;95 (1):58-66 [PubMed]
  • Hughes J. M., Brink A., Witmer A. N., Hanraads-de Riemer M., Klaassen I., Schlingemann R. O. Vascular leucocyte adhesion molecules unaltered in the human retina in diabetes British journal of ophthalmology 2004;88 (4):566-572 [PubMed]

2003

  • D'Amico Donald J., Goldberg Morton F., Hudson Henry, Jerdan Janice A., Krueger D. Scott, Luna Susan P., Robertson Stella M., Russell Stephen, Singerman Lawrence, Slakter Jason S., Yannuzzi Lawrence, Zilliox Patricia, de Smet M. D., Verbraak F. D., Tan H. Stevie, Schlingemann R. O., Sital O. N., Eveleens A., Kruissel N., Vermeulen M. Anecortave acetate as monotherapy for treatment of subfoveal neovascularization in age-related macular degeneration: twelve-month clinical outcomes Ophthalmology 2003;110 (12):2372-83; discussin 2384-5 [PubMed]
  • Schlingemann R. O. Boekbespreking: Emergency ophtalmology. A rapid treatment guide Nederlands tijdschrift voor geneeskunde 2003;147 (35):1712
  • Schlingemann R. O. Boekbespreking: Practical viewing of the optic disc Nederlands tijdschrift voor geneeskunde 2003;147 (36):1766-1767
  • Schlingemann R. O. Duisternis leidt mogelijk tot verergering van diabetische retinopathie Nederlands tijdschrift voor geneeskunde 2003;147 (4):179-180
  • Missotten Guy S., Journée-de Korver Johanna G., de Wolff-Rouendaal Didi, Keunen Jan E., Schlingemann Reinier O., Jager Martine J. Heat shock protein expression in the eye and in uveal melanoma Investigative ophthalmology & visual science 2003;44 (7):3059-3065 [PubMed]
  • Verbraak F. D., Schlingemann R. O., Keunen J. E. E., de Smet M. D. Longstanding symptomatic choroidal hemangioma managed with limited PDT as initial or salvage therapy Graefe s archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 2003;241 (11):891-898 [PubMed]
  • Witmer A. N., Vrensen G. F. J. M., van Noorden C. J. F., Schlingemann R. O. Vascular endothelial growth factors and angiogenesis in eye disease Progress in retinal and eye research 2003;22 (1):1-29 [PubMed]

2002

  • Witmer Antonella N., Blaauwgeers Harriet G., Weich Herbert A., Alitalo Kari, Vrensen Gijs F. J. M., Schlingemann Reinier O. Altered expression patterns of VEGF receptors in human diabetic retina and in experimental VEGF-induced retinopathy in monkey Investigative ophthalmology & visual science 2002;43 (3):849-857 [PubMed]
  • Dai Jiapei, Vrensen Gijs F. J. M., Schlingemann Reinier O. Blood-brain barrier integrity is unaltered. in human brain cortex with diabetes mellitus Brain research 2002;954 (2):311-316 [PubMed]
  • Schlingemann R. O., Brink H. M. A., Völker-Dieben H. J. M. De standaard "Refractieafwijkingen" van het Nederlands Huisartsen Genootschap: reactie vanuit de oogheelkunde Nederlands tijdschrift voor geneeskunde 2002;146 (38):1771-1774 [PubMed]
  • Witmer Antonella N., Dai Jiapei, Weich Herbert A., Vrensen Gijs F. J. M., Schlingemann Reinier O. Expression of vascular endothelial growth factor receptors 1, 2, and 3 in quiescent endothelia journal of histochemistry and cytochemistry 2002;50 (6):767-777 [PubMed]
  • Marinkovic M., van Lanschot J. J. B., Schlingemann R. O., de Smet M. D., Saeed P. Oogklachten wijzend op een tumor elders in het lichaam Nederlands tijdschrift voor geneeskunde 2002;146 (50):2393-2396 [PubMed]
  • Schlingemann R. O., Nieuwendaal C. P. Oogproblemen door contactlenzen: een advies van de Gezondheidsraad Nederlands tijdschrift voor geneeskunde 2002;146 (35):1616-1619 [PubMed]
  • Witmer A. N. (Patho)physiological role of VEGFs in the eye 2002. 193p. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van Noorden C. J. F., Vrensen G. F. J. M.; Co-supervisor: Schlingemann R. O.)
  • Schlingemann R. O. Vernauwde retinale arteriolen zijn een onafhankelijke voorspeller van diabetes mellitus type 2: referaat Nederlands tijdschrift voor geneeskunde 2002;146 (40):1909

2001

  • Lahdenranta J., Pasqualini R., Schlingemann R. O., Hagedorn M., Stallcup W. B., Bucana C. D., Sidman R. L., Arap W. An anti-angiogenic state in mice and humans with retinal photoreceptor cell degeneration Proceedings of the National Academy of Sciences of the United States of America 2001;98 (18):10368-10373 [PubMed]
  • Hofman P., van Blijswijk B. C., Gaillard P. J., Vrensen G. F., Schlingemann R. O. Endothelial cell hypertrophy induced by vascular endothelial growth factor in the retina: new insights into the pathogenesis of capillary nonperfusion Archives of ophthalmology 2001;119 (6):861-866 [PubMed]
  • Hofman P., Hoyng P., VanderWerf F., Vrensen G. F., Schlingemann R. O. Lack of blood-brain barrier properties in microvessels of the prelaminar optic nerve head Investigative ophthalmology & visual science 2001;42 (5):895-901 [PubMed]
  • Hofman P., Blaauwgeers H. G., Vrensen G. F., Schlingemann R. O. Role of VEGF-A in endothelial phenotypic shift in human diabetic retinopathy and VEGF-A-induced retinopathy in monkeys Ophthalmic research 2001;33 (3):156-162 [PubMed]
  • Witmer A. N., van den Born J., Vrensen G. F., Schlingemann R. O. Vascular localization of heparan sulfate proteoglycans in retinas of patients with diabetes mellitus and in VEGF-induced retinopathy using domain-specific antibodies Current eye research 2001;22 (3):190-197 [PubMed]
  • Witmer A. N., van Blijswijk B. C., Dai J., Hofman P., Partanen T. A., Vrensen G. F., Schlingemann R. O. VEGFR-3 in adult angiogenesis Journal of pathology 2001;195 (4):490-497 [PubMed]

2000

  • Hofman P., Blaauwgeers H. G., Tolentino M. J., Adamis A. P., Nunes Cardozo B. J., Vrensen G. F., Schlingemann R. O. VEGF-A induced hyperpermeability of blood-retinal barrier endothelium in vivo is predominantly associated with pinocytotic vesicular transport and not with formation of fenestrations. Vascular endothelial growth factor-A Current eye research 2000;21 (2):637-645 [PubMed]

1999

  • Schalkwijk C. G., Ligtvoet N., Twaalfhoven H., Jager A., Blaauwgeers H. G., Schlingemann R. O., Tarnow L., Parving H. H., Stehouwer C. D., van Hinsbergh V. W. Amadori albumin in type 1 diabetic patients: correlation with markers of endothelial function, association with diabetic nephropathy, and localization in retinal capillaries Diabetes 1999;48 (12):2446-2453 [PubMed]
  • Schlingemann R. O., Hofman P., Vrensen G. F., Blaauwgeers H. G. Increased expression of endothelial antigen PAL-E in human diabetic retinopathy correlates with microvascular leakage Diabetologia 1999;42 (5):596-602 [PubMed]
  • Blaauwgeers H. G., Holtkamp G. M., Rutten H., Witmer A. N., Koolwijk P., Partanen T. A., Alitalo K., Kroon M. E., Kijlstra A., van Hinsbergh V. W., Schlingemann R. O. Polarized vascular endothelial growth factor secretion by human retinal pigment epithelium and localization of vascular endothelial growth factor receptors on the inner choriocapillaris. Evidence for a trophic paracrine relation American journal of pathology 1999;155 (2):421-428 [PubMed]

1998

  • Schlingemann R. O., Hofman P., Klooster J., Blaauwgeers H. G., van der Gaag R., Vrensen G. F. Ciliary muscle capillaries have blood-tissue barrier characteristics Experimental eye research 1998;66 (6):747-754 [PubMed]

1997

  • Schlingemann R. O., van Hinsbergh V. W. Role of vascular permeability factor/vascular endothelial growth factor in eye disease British journal of ophthalmology 1997;81 (6):501-512 [PubMed]
  • Schlingemann R. O., Hofman P., Anderson L., Troost D., van der Gaag R. Vascular expression of endothelial antigen PAL-E indicates absence of blood-ocular barriers in the normal eye Ophthalmic research 1997;29 (3):130-138 [PubMed]

1996

  • Schlingemann R. O., Smit A. A., Lunel H. F., Hijdra A. Amaurosis fugax on standing and angle-closure glaucoma with clomipramine Lancet 1996;347 (8999):465 [PubMed]
  • Schlingemann R. O., Oosterwijk E., Wesseling P., Rietveld F. J., Ruiter D. J. Aminopeptidase a is a constituent of activated pericytes in angiogenesis Journal of pathology 1996;179 (4):436-442 [PubMed]
  • Mombaerts I., Schlingemann R. O., Goldschmeding R., Koornneef L. Are systemic corticosteroids useful in the management of orbital pseudotumors? Ophthalmology 1996;103 (3):521-528 [PubMed]
  • Schlingemann R. O., Wertheim-van Dillen P., Kijlstra A., Bos P. J., Meenken C., Feron E. J. Bilateral cytomegalovirus retinitis in a patient with systemic lupus erythematosus British journal of ophthalmology 1996;80 (12):1109-1110 [PubMed]
  • Brans J. W., Aramideh M., Schlingemann R. O., Oen V. M., Speelman J. D., Ongerboer de Visser B. W. Corneabescherming door ptosis opgewekt door botuline-injectie Nederlands tijdschrift voor geneeskunde 1996;140 (19):1031-1033 [PubMed]
  • Mombaerts I., Schlingemann R. O., Goldschmeding R., Koornneef L. Idiopathic granulomatous orbital inflammation Ophthalmology 1996;103 (12):2135-2141 [PubMed]
  • Mombaerts I., Schlingemann R. O., Goldschmeding R., Noorduyn L. A., Koornneef L. The surgical management of lacrimal gland pseudotumors Ophthalmology 1996;103 (10):1619-1627 [PubMed]
  • Schlingemann R. O., Bruinenberg M., Wertheim-van Dillen P., Feron E. Twenty years' delay of fellow eye involvement in herpes simplex virus type 2-associated bilateral acute retinal necrosis syndrome American journal of ophthalmology 1996;122 (6):891-892 [PubMed]
  • Mombaerts I., Goldschmeding R., Schlingemann R. O., Koornneef L. What is orbital pseudotumor? Survey of ophthalmology 1996;41 (1):66-78 [PubMed]

1995

  • Wesseling P., Schlingemann R. O., Rietveld F. J., Link M., Burger P. C., Ruiter D. J. Early and extensive contribution of pericytes/vascular smooth muscle cells to microvascular proliferation in glioblastoma multiforme: an immuno-light and immuno-electron microscopic study Journal of neuropathology and experimental neurology 1995;54 (3):304-310 [PubMed]

1993

  • Ruiter D. J., Schlingemann R. O., Westphal J. R., Denijn M., Rietveld F. J., de Waal R. M. Angiogenesis in wound healing and tumor metastasis Behring Institute Mitteilungen 1993;92:258-272 [PubMed]

1991

  • Schlingemann R. O., Rietveld F. J., Kwaspen F., van de Kerkhof P. C., de Waal R. M., Ruiter D. J. Differential expression of markers for endothelial cells, pericytes, and basal lamina in the microvasculature of tumors and granulation tissue American journal of pathology 1991;138 (6):1335-1347 [PubMed]

1990

  • Schlingemann R. O., Rietveld F. J., de Waal R. M., Ferrone S., Ruiter D. J. Expression of the high molecular weight melanoma-associated antigen by pericytes during angiogenesis in tumors and in healing wounds American journal of pathology 1990;136 (6):1393-1405 [PubMed]
  • Schlingemann R. O., Rietveld F. J., de Waal R. M., Bradley N. J., Skene A. I., Davies A. J., Greaves M. F., Denekamp J., Ruiter D. J. Leukocyte antigen CD34 is expressed by a subset of cultured endothelial cells and on endothelial abluminal microprocesses in the tumor stroma Laboratory investigation; a journal of technical methods and pathology 1990;62 (6):690-696 [PubMed]

1989

  • Verheijen R., Kuijpers H. J., Schlingemann R. O., Boehmer A. L., van Driel R., Brakenhoff G. J., Ramaekers F. C. Ki-67 detects a nuclear matrix-associated proliferation-related antigen. I. Intracellular localization during interphase Journal of cell science 1989;92 ( Pt 1):123-130 [PubMed]
  • Ruiter D. J., Schlingemann R. O., Rietveld F. J., de Waal R. M. Monoclonal antibody-defined human endothelial antigens as vascular markers Journal of investigative dermatology 1989;93 (2 Suppl):25S-32S [PubMed]

1988

  • Sarawar S. R., Schlingemann R. O., Kelsey A., Fleming S., Kumar S. A monoclonal antibody stains blastemal but not tubular components of Wilms' tumour Journal of pathology 1988;156 (4):319-324 [PubMed]

1986

  • Hagen E. C., Vennegoor C., Schlingemann R. O., van der Velde E. A., Ruiter D. J. Correlation of histopathological characteristics with staining patterns in human melanoma assessed by (monoclonal) antibodies reactive on paraffin sections Histopathology 1986;10 (7):689-700 [PubMed]

1985

  • Schlingemann R. O., Dingjan G. M., Emeis J. J., Blok J., Warnaar S. O., Ruiter D. J. Monoclonal antibody PAL-E specific for endothelium Laboratory investigation; a journal of technical methods and pathology 1985;52 (1):71-76 [PubMed]