Prof. W.S. Schlack MD PhD publications

foto

Publications Prof. MD PhD W.S. Schlack

Position
Full Professor
Main activities
Education, Patient care, Other
Specialisation
Anesthesiology
Focus of research

Anesthesia for the cardiac risk patient

Carioprotective effects of anesthetic agents and anesthetic strategies

2020

  • Preckel Benedikt, Schultz Marcus J, Vlaar Alexander P, Hulst Abraham H, Hermanides Jeroen, de Jong Menno D, Schlack Wolfgang S, Stevens Markus F, Hollmann Markus W Update for Anaesthetists on Clinical Features of COVID-19 Patients and Relevant Management Journal of clinical medicine 2020;9 (5) [PubMed]

2019

  • van Dalen A. S. H. M., Legemaate J., Schlack W. S., Legemate D. A., Schijven M. P. Legal perspectives on black box recording devices in the operating environment British journal of surgery 2019;106 (11):1433-1441 [PubMed]

2018

  • Koers Lena, Eberl Suzanne, Cappon Anne, Bouwman Arthur, Schlack Wolfgang, Hermanides Jeroen, Preckel Benedikt Safety of moderate-to-deep sedation performed by sedation practitioners: A national prospective observational study European journal of anaesthesiology 2018;35 (9):659-666 [PubMed]

2017

  • Koers Lena, Schlack Wolfgang S., Hollmann Markus W., de Hert Stefan, Preckel Benedikt European implementation of the "2014 ESC/ESA guideline on non-cardiac surgery: cardiovascular assessment and management" Minerva anestesiologica 2017;83 (5):457-464 [PubMed]
  • Welsink-Karssies M. M., Polderman J. A. W., Nieveen van Dijkum E. J., Preckel B., Schlack W. S., Visser G., Hollak C. E., Hermanides J. Very Long-Chain Acyl-Coenzyme A Dehydrogenase Deficiency and Perioperative Management in Adult Patients JIMD reports 2017;34:49-54 [PubMed]

2016

  • Smit Kirsten F., Brevoord Daniel, de Hert Stefan, de Mol Bas A., Kerindongo Raphaela P., van Dieren Susan, Schlack Wolfgang S., Hollmann Markus W., Weber Nina C., Preckel Benedikt Effect of helium pre- or postconditioning on signal transduction kinases in patients undergoing coronary artery bypass graft surgery Journal of translational medicine 2016;14 (1):294 [PubMed]
  • Koers L., Schlack W. S., Preckel B. Veiligheid op de operatiekamer A&I : Nascholingstijdschrift over perioperatieve geneeskunde 2016;2015 (1)

2015

  • Koers Lena, Eveleens Fiona M., Schlack Wolfgang S., Preckel Benedikt Cognitieve leidraad voor noodgevallen op de OK--AMC-bundel helpt om geen stappen te vergeten Nederlands tijdschrift voor geneeskunde 2015;159:A8325 [PubMed]

2014

  • Kooij F. O., Preckel B., Schlack W. S., Hollmann M. W. CON: Epidural analgesia for major truncal surgery: pain relief but nothing more Nederlands tijdschrift voor anesthesiologie 2014;27 (5):13-20
  • Koers L., Hermanns H., Schlack W. S., Preckel B. De belangrijkste veranderingen in de nieuwe richtlijnen cardiale risicopatiënt (ESC/ESA) Nederlands tijdschrift voor anesthesiologie 2014;27 (5):29-36
  • Kooij Fabian O., Schlack Wolfgang S., Preckel Benedikt, Hollmann Markus W. Does regional analgesia for major surgery improve outcome? Focus on epidural analgesia Anesthesia and analgesia 2014;119 (3):740-744 [PubMed]
  • Dyballa-Rukes Nadine, Schuh Christian, Vogt Hendrik, Toma Octavian, Schlack Wolfgang S., Weber Nina C., Metzger Sabine In vivo desflurane preconditioning evokes dynamic alterations of metabolic proteins in the heart--proteomic insights strengthen the link between bioenergetics and cardioprotection Cellular physiology and biochemistry 2014;33 (4):967-981 [PubMed]

2013

  • Smit Kirsten F., Oei Gezina T. M. L., Brevoord Daniel, Stroes Erik S., Nieuwland Rienk, Schlack Wolfgang S., Hollmann Markus W., Weber Nina C., Preckel Benedikt Helium induces preconditioning in human endothelium in vivo Anesthesiology 2013;118 (1):95-104 [PubMed]

2012

  • Huhn Ragnar, Weber Nina C., Preckel Benedikt, Schlack Wolfgang, Bauer Inge, Hollmann Markus W., Heinen André Age-related loss of cardiac preconditioning: Impact of protein kinase A Experimental gerontology 2012;47 (1):116-121 [PubMed]
  • Frässdorf Jan Anesthetic induced cardioprotection: from bench to bedside and retour 2012. 318p. ISBN 9789088914928. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Hollmann M. W., Schlack W. S.; Co-supervisors: Hauck N. C., Preckel B.)
  • de Kant-Pariama Esther, Preckel Benedikt, Schlack Wolfgang S., van Dijkum Els J. M. Nieveen Cuff Perforation by Dislocated Electrodes of an Electromyogram Tube Anesthesia and analgesia 2012;115 (6):1473 [PubMed]
  • Oei Gezina T. M. L., Huhn Ragnar, Heinen Andre, Hollmann Markus W., Schlack Wolfgang S., Preckel Benedikt, Weber Nina C. Helium-induced cardioprotection of healthy and hypertensive rat myocardium in vivo European journal of pharmacology 2012;684 (1-3):125-131 [PubMed]

2011

  • Brevoord Daniel, Hollmann Markus W., de Hert Stefan G., van Dongen Eric H. P. A., Heijnen Bram G. A. D. H., de Bruin Anton, Tolenaar Noortje, Schlack Wolfgang S., Weber Nina C., Dijkgraaf Marcel G. W., de Groot Joris R., de Mol Bas A. J. M., Driessen Antoine H. G., Momeni Mona, Wouters Patrick, Bouchez Stefaan, Hofland Jan, Luthen Christian, Meijer-Treschan Tanja A., Pannen Benedikt H., Preckel Benedikt Effect of Remote Ischemic Conditioning on atrial fibrillation and Outcome after coronary artery bypass grafting (RICO-trial) BMC anesthesiology 2011;11 (1):11 [PubMed]
  • Schlack Wolfgang S., de Hert Stefan G., Hollmann Markus W. Epidurals and outcome after cardiac surgery: an example of wishful thinking? Journal of cardiothoracic and vascular anesthesia 2011;25 (4):e17-9; author reply e19-20 [PubMed]

2010

  • Huhn R., Heinen A., Hollmann M. W., Schlack W., Preckel B., Weber N. C. Cyclosporine A administered during reperfusion fails to restore cardioprotection in prediabetic Zucker obese rats in vivo Nutrition, metabolism, and cardiovascular diseases 2010;20 (10):706-712 [PubMed]
  • de Vries Eefje N., Prins Hubert A., Crolla Rogier M. P. H., den Outer Adriaan J., van Andel George, van Helden Sven H., Schlack Wolfgang S., van Putten M. Agnès, Gouma Dirk J., Dijkgraaf Marcel G. W., Smorenburg Susanne M., Boermeester Marja A. Effect of a comprehensive surgical safety system on patient outcomes New England journal of medicine 2010;363 (20):1928-1937 [PubMed]
  • Berger Marc M., Huhn Ragnar, Oei Gezina T., Heinen André, Winzer Andreas, Bauer Inge, Preckel Benedikt, Weber Nina C., Schlack Wolfgang, Hollmann Markus W. Hypoxia Induces Late Preconditioning in the Rat Heart In Vivo Anesthesiology 2010;113 (6):1351-1360 [PubMed]
  • Huhn R., Heinen A., Weber N. C., Schlack W., Preckel B., Hollmann M. W. Ischaemic and morphine-induced post-conditioning: impact of mK(Ca) channels British journal of anaesthesia 2010;105 (5):589-595 [PubMed]
  • Fräßdorf Jan, Huhn Ragnar, Niersmann Corinna, Weber Nina C., Schlack Wolfgang, Preckel Benedikt, Hollmann Markus W. Morphine induces preconditioning via activation of mitochondrial K(Ca) channels La morphine provoque le préconditionnement par l'activation des canaux mitochondriaux K(Ca) Canadian journal of anaesthesia = Journal canadien d'anesthésie 2010;57 (8):767-773 [PubMed]
  • Schlack Wolfgang S., Boermeester Marja A. Patient safety during anaesthesia: incorporation of the WHO safe surgery guidelines into clinical practice Current opinion in anaesthesiology 2010;23 (6):754-758 [PubMed]
  • Preckel B., Poels M., Wappler F., Schlack W., Buhre W. Perioperative beta-Rezeptoren-Blockade. Für und Wider Anaesthesist 2010;59 (7):643-651 [PubMed]
  • Schwiebert Christian, Huhn Ragnar, Heinen Andre, Weber Nina C., Hollmann Markus W., Schlack Wolfgang, Preckel Benedikt Postconditioning by xenon and hypothermia in the rat heart in vivo European journal of anaesthesiology 2010;27 (8):734-739 [PubMed]
  • Fräßdorf Jan, Huhn Ragnar, Weber Nina C., Ebel Dirk, Wingert Nadja, Preckel Benedikt, Toma Octavian, Schlack Wolfgang, Hollmann Markus W. Sevoflurane-induced Preconditioning Impact of Protocol and Aprotinin Administration on Infarct Size and Endothelial Nitric-Oxide Synthase Phosphorylation in the Rat Heart In Vivo Anesthesiology 2010;113 (6):1289-1298 [PubMed]

2009

  • Fräßdorf J., de Hert S., Schlack W. Anaesthesia and myocardial ischaemia/reperfusion injury British journal of anaesthesia 2009;103 (1):89-98 [PubMed]
  • Huhn Ragnar Cardioprotection with helium and anesthetics in healthy and diseased myocardium 2009. 187p. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Schlack W. S., Hollmann M. W.; Co-supervisors: Preckel B., Hauck N. C.)
  • de Hert Stefan G., Preckel Benedikt, Hollmann Markus W., Schlack Wolfgang S. Drugs mediating myocardial protection European journal of anaesthesiology 2009;26 (12):985-995 [PubMed]
  • Huhn R., Heinen A., Weber N. C., Kerindongo R. P., Oei G. T. M. L., Hollmann M. W., Schlack W., Preckel B. Helium-induced early preconditioning and postconditioning are abolished in obese Zucker rats in vivo Journal of pharmacology and experimental therapeutics 2009;329 (2):600-607 [PubMed]
  • Huhn R., Heinen A., Weber N. C., Hieber S., Hollmann M. W., Schlack W., Preckel B. Helium-induced late preconditioning in the rat heart in vivo British journal of anaesthesia 2009;102 (5):614-619 [PubMed]
  • Frässdorf Jan, Borowski Andreas, Ebel Dirk, Feindt Peter, Hermes Manuel, Meemann Thomas, Weber René, Müllenheim Jost, Weber Nina C., Preckel Benedikt, Schlack Wolfgang Impact of preconditioning protocol on anesthetic-induced cardioprotection in patients having coronary artery bypass surgery Journal of thoracic and cardiovascular surgery 2009;137 (6):1436-42, 1442.e1-2 [PubMed]
  • Ebel D., Toma O., Appler S., Baumann K., Fräßdorf J., Preckel B., Rösen P., Schlack W., Weber N. C. Ischemic Preconditioning Phosphorylates Mitogen-activated Kinases and Heat Shock Protein 27 in the Diabetic Rat Heart Hormone and metabolic research. Hormon- und Stoffwechselforschung. Hormones et metabolisme 2009;41 (1):10-15 [PubMed]
  • de Hert Stefan G., Preckel Benedikt, Schlack Wolfgang S. Update on inhalational anaesthetics Current opinion in anaesthesiology 2009;22 (4):491-495 [PubMed]

2008

  • Weber Nina C., Goletz Christine, Huhn Ragnar, Grueber Yvonne, Preckel Benedikt, Schlack Wolfgang, Ebel Dirk Blockade of anaesthetic-induced preconditioning in the hyperglycaemic myocardium - The regulation of different mitogen-activated protein kinases European journal of pharmacology 2008;592 (1-3):48-54 [PubMed]
  • Edward G. M., Biervliet J. D., Hollmann M. W., Schlack W. S., Preckel B. Comparing the organisational structure of the preoperative assessment clinic at eight university hospitals Acta anaesthesiologica Belgica 2008;59 (1):33-37 [PubMed]
  • Ley S. C., Freund R., Bössenroth W. A., Scherbaum W. A., Schlack W. S., Preckel B. Datenlage zur perioperativen Diabetesbetreuung in einem Universitätsklinikum DIABETOLOGE 2008;4 (1):13-19
  • Preckel Benedikt, Schlack Wolfgang Drug Eluting Stents und Antikoagulation in der perioperativen Phase - Eine interdisziplinäre Aufgabe Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie 2008;43 (9):596-601 [PubMed]
  • Heinen Andre, Huhn Ragnar, Smeele Kirsten M. A., Zuurbier Coert J., Schlack Wolfgang, Preckel Benedikt, Weber Nina C., Hollmann Markus W. Helium-induced preconditioning in young and old rat heart: impact of mitochondrial Ca(2+) -sensitive potassium channel activation Anesthesiology 2008;109 (5):830-836 [PubMed]
  • Huhn R., Heinen A., Weber N. C., Hollmann M. W., Schlack W., Preckel B. Hyperglycaemia blocks sevoflurane-induced postconditioning in the rat heart in vivo: cardioprotection can be restored by blocking the mitochondrial permeability transition pore British journal of anaesthesia 2008;100 (4):465-471 [PubMed]
  • Weber N. C., Schlack W. Inhalational anaesthetics and cardioprotection Handbook of experimental pharmacology 2008;182 (182):187-207 [PubMed]
  • Weber Nina C., Kandler Jennis, Schlack Wolfgang, Grueber Yvonne, Frädorf Jan, Preckel Benedikt Intermitted pharmacologic pretreatment by xenon, isoflurane, nitrous oxide, and the opioid morphine prevents tumor necrosis factor alpha-induced adhesion molecule expression in human umbilical vein endothelial cells Anesthesiology 2008;108 (2):199-207 [PubMed]
  • Weber Nina C., Schlack Wolfgang, Preckel Benedikt Molecular biology in cardiovascular anaesthesia Current opinion in anaesthesiology 2008;21 (1):71-77 [PubMed]
  • Allison C. E., Aronson D. C., Geukers V. G. M., van den Berg R., Schlack W. S., Hollmann M. W. Paraplegia after thoracotomy under combined general and epidural anesthesia in a child Paediatric anaesthesia 2008;18 (6):539-542 [PubMed]
  • Heinen André, Huhn Ragnar, Hollmann Markus W., Preckel Benedikt, Zuurbier Coert J., Schlack Wolfgang, Frässdorf Jan, Weber Nina C. Physiological levels of glutamine prevent morphine-induced preconditioning in the isolated rat heart European journal of pharmacology 2008;595 (1-3):58-64 [PubMed]
  • Heinen André, Winning Adrian, Schlack Wolfgang, Hollmann Markus W., Preckel Benedikt, Frässdorf Jan, Weber Nina C. The regulation of mitochondrial respiration by opening of mKCa channels is age-dependent European journal of pharmacology 2008;578 (2-3):108-113 [PubMed]
  • Heinen André The role of mitochondria in cardioprotection 2008. 177p. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Hollmann M. W., Schlack W. S.; Co-supervisors: Hauck N. C., Preckel B.)
  • Weber Nina C., Fräβdorf Jan, Ratajczak Christoph, Grueber Yvonne, Schlack Wolfgang, Hollmann Markus W., Preckel Benedikt Xenon Induces Late Cardiac Preconditioning In Vivo: A Role for Cyclooxygenase 2? Anesthesia and analgesia 2008;107 (6):1807-1813 [PubMed]

2007

  • Lombarts M. J. M. H., Bucx M. J. L., Rupp I., Keijzers P. J., Kokke S. I. M., Schlack W. Een instrument voor de evaluatie van opleiderskwaliteiten van stafleden Nederlands tijdschrift voor geneeskunde 2007;151 (36):2004-2008 [PubMed]
  • Barthel Holger, Südkamp Hendrik, Ebel Dirk, Müllenheim Jost, Schlack Wolfgang, Preckel Benedikt Influence of the interleukin-converting enzyme inhibitor HMR-3480 on myocardial stunning in pigs in vivo Experimental and clinical cardiology 2007;12 (3):125-131 [PubMed]
  • Vranken Jan H. The good, the bad, and the ugly: treatment of neuropathic pain 2007. 184p. ISBN 9789789067510. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Hollmann Markus W.; Co-supervisor: Schlack W. S.)

2006

  • Obal D., Dettwiler S., Favoccia C., Rascher K., Preckel B., Schlack W. Effect of sevoflurane preconditioning on ischaemia/reperfusion injury in the rat kidney in vivo European journal of anaesthesiology 2006;23 (4):319-326 [PubMed]
  • Preckel Benedikt, Obal Detlef, Müllenheim Jost, Hennes Juliane, Heiderhoff Marc, Thämer Volker, Schlack Wolfgang Effects of halothane, sevoflurane and desflurane on the force-frequency relation in the dog heart in vivo Canadian journal of anaesthesia = Journal canadien d'anesthésie 2006;53 (11):1118-1125 [PubMed]
  • Frässdorf Jan, Luther Bernd, Müllenheim Jost, Otto Florian, Preckel Benedikt, Schlack Wolfgang, Thämer Volker Influence of groin incision, duration of ischemia, and prostaglandin E1 on ischemia-reperfusion injury of the lower limb Journal of cardiothoracic and vascular anesthesia 2006;20 (2):187-195 [PubMed]
  • Preckel Benedikt, Weber Nina C., Sanders Robert D., Maze Mervyn, Schlack Wolfgang Molecular mechanisms transducing the anesthetic, analgesic, and organ-protective actions of xenon Anesthesiology 2006;105 (1):187-197 [PubMed]
  • Weber Nina C., Preckel Benedikt, Schlack Wolfgang Nitrous oxide and preconditioning - Reply Anesthesiology 2006;105 (3):631
  • Obal D., Rascher K., Favoccia C., Dettwiler S., Schlack W. Post-conditioning by a short administration of desflurane reduced renal reperfusion injury after differing of ischaemia times in rats British journal of anaesthesia 2006;97 (6):783-791 [PubMed]
  • Weber Nina C., Toma Octavian, Damla Halil, Wolter Jessica I., Schlack Wolfgang, Preckel Benedikt Upstream signaling of protein kinase C-epsilon in xenon-induced pharmacological preconditioning. Implication of mitochondrial adenosine triphosphate dependent potassium channels and phosphatidylinositol-dependent kinase-1 European journal of pharmacology 2006;539 (1-2):1-9 [PubMed]
  • Weber N. C., Stursberg J., Wirthle N. M., Toma O., Schlack W., Preckel B. Xenon preconditioning differently regulates p44/42 MAPK (ERK 1/2) and p46/54 MAPK (JNK 1/2 and 3) in vivo British journal of anaesthesia 2006;97 (3):298-306 [PubMed]

2005

  • Obal D., Kindgen-Milles D., Schoebel F., Schlack W. Coronary artery angioplasty for treatment of peri-operative myocardial ischaemia Anaesthesia 2005;60 (2):194-197 [PubMed]
  • Weber Nina C., Toma Octavian, Awan Saqib, Frässdorf Jan, Preckel Benedikt, Schlack Wolfgang Effects of nitrous oxide on the rat heart in vivo: another inhalational anesthetic that preconditions the heart? Anesthesiology 2005;103 (6):1174-1182 [PubMed]
  • Preckel Benedikt, Schlack Wolfgang Inert gases as the future inhalational anaesthetics? Best practice & research. Clinical anaesthesiology 2005;19 (3):365-379 [PubMed]
  • Preckel Benedikt, Weber N. C., Schlack W. Kardioprotektion durch xenon Journal fur Anasthesie und Intensivbehandlung 2005;12 (2):102
  • Weber Nina C., Toma Octavian, Wolter Jessica I., Wirthle Nicole M., Schlack Wolfgang, Preckel Benedikt Mechanisms of xenon- and isoflurane-induced preconditioning - a potential link to the cytoskeleton via the MAPKAPK-2/HSP27 pathway British journal of pharmacology 2005;146 (3):445-455 [PubMed]
  • Ebel D., Redler S., Preckel B., Schlack W., Thämer V. Moderate glucose deprivation preconditions myocardium against infarction Hormone and metabolic research. Hormon- und Stoffwechselforschung. Hormones et metabolisme 2005;37 (8):516-520 [PubMed]
  • Frässdorf Jan, Weber Nina C., Obal Detlef, Toma Octavian, Müllenheim Jost, Kojda Georg, Preckel Benedikt, Schlack Wolfgang Morphine induces late cardioprotection in rat hearts in vivo: the involvement of opioid receptors and nuclear transcription factor kappaB Anesthesia and analgesia 2005;101 (4):934-41, table of contents [PubMed]
  • Ley S. C., Preckel B., Schlack W. Perioperative Behandlung von Patienten mit Diabetes mellitus Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie 2005;40 (4):230-46; quiz 247-9 [PubMed]
  • Obal D., Weber N. C., Zacharowski K., Toma O., Dettwiler S., Wolter J. I., Kratz M., Müllenheim J., Preckel B., Schlack W. Role of protein kinase C-epsilon (PKCepsilon) in isoflurane-induced cardioprotection British journal of anaesthesia 2005;94 (2):166-173 [PubMed]
  • Weber Nina C., Schlack Wolfgang The concept of anaesthetic-induced cardioprotection: mechanisms of action Best practice & research. Clinical anaesthesiology 2005;19 (3):429-443 [PubMed]
  • Weber N. C., Preckel B., Schlack W. The effect of anaesthetics on the myocardium--new insights into myocardial protection European journal of anaesthesiology 2005;22 (9):647-657 [PubMed]
  • Obal Detlef, Dettwiler Saskia, Favoccia Christian, Scharbatke Horst, Preckel Benedikt, Schlack Wolfgang The influence of mitochondrial KATP-channels in the cardioprotection of preconditioning and postconditioning by sevoflurane in the rat in vivo Anesthesia and analgesia 2005;101 (5):1252-1260 [PubMed]
  • Weber Nina C., Toma Octavian, Wolter Jessica I., Obal Detlef, Müllenheim Jost, Preckel Benedikt, Schlack Wolfgang The noble gas xenon induces pharmacological preconditioning in the rat heart in vivo via induction of PKC-epsilon and p38 MAPK British journal of pharmacology 2005;144 (1):123-132 [PubMed]

2004

  • Toma Octavian, Weber Nina C., Wolter Jessica I., Obal Detlef, Preckel Benedikt, Schlack Wolfgang Desflurane preconditioning induces time-dependent activation of protein kinase C epsilon and extracellular signal-regulated kinase 1 and 2 in the rat heart in vivo Anesthesiology 2004;101 (6):1372-1380 [PubMed]
  • Preckel B., Schlack W. Editorial III: xenon--cardiovascularly inert? British journal of anaesthesia 2004;92 (6):786-789 [PubMed]
  • Barthel H., Ebel D., Müllenheim J., Obal D., Preckel B., Schlack W. Effect of lidocaine on ischaemic preconditioning in isolated rat heart British journal of anaesthesia 2004;93 (5):698-704 [PubMed]
  • Preckel B., Müllenheim J., Hoff J., Obal D., Heiderhoff M., Thämer V., Schlack W. Haemodynamic changes during halothane, sevoflurane and desflurane anaesthesia in dogs before and after the induction of severe heart failure European journal of anaesthesiology 2004;21 (10):797-806 [PubMed]
  • Ebel Dirk, Müllenheim Jost, Südkamp Hendrik, Bohlen Thomas, Ferrari Jan, Huhn Ragnar, Preckel Benedikt, Schlack Wolfgang Role of tyrosine kinase in desflurane-induced preconditioning Anesthesiology 2004;100 (3):555-561 [PubMed]
  • Preckel B., Weber N., Schlack W. Xenon - Edelgas mit organprotektiven Eigenschaften Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie 2004;39 (8):456-462 [PubMed]

2003

  • Obal Detlef, Scharbatke Horst, Barthel Holger, Preckel Benedikt, Müllenheim Jost, Schlack Wolfgang Cardioprotection against reperfusion injury is maximal with only two minutes of sevoflurane administration in rats Canadian journal of anaesthesia = Journal canadien d'anesthésie 2003;50 (9):940-945 [PubMed]
  • Ebel Dirk, Müllenheim Jost, Frässdorf Jan, Heinen Andre, Huhn Ragnar, Bohlen Thomas, Ferrari Jan, Südkamp Hendrik, Preckel Benedikt, Schlack Wolfgang, Thämer Volker Effect of acute hyperglycaemia and diabetes mellitus with and without short-term insulin treatment on myocardial ischaemic late preconditioning in the rabbit heart in vivo Pflugers Archiv 2003;446 (2):175-182 [PubMed]
  • Müllenheim Jost, Ebel Dirk, Bauer Mirco, Otto Florian, Heinen André, Frässdorf Jan, Preckel Benedikt, Schlack Wolfgang Sevoflurane confers additional cardioprotection after ischemic late preconditioning in rabbits Anesthesiology 2003;99 (3):624-631 [PubMed]

2002

  • Ebel D., Preckel B., You A., Müllenheim J., Schlack W., Thämer V. Cardioprotection by sevoflurane against reperfusion injury after cardioplegic arrest in the rat is independent of three types of cardioplegia British journal of anaesthesia 2002;88 (6):828-835 [PubMed]
  • Müllenheim Jost, Ebel Dirk, Frässdorf Jan, Preckel Benedikt, Thämer Volker, Schlack Wolfgang Isoflurane preconditions myocardium against infarction via release of free radicals Anesthesiology 2002;96 (4):934-940 [PubMed]
  • Laussmann Tim, Janosi Rolf Alexander, Fingas Christina Dominik, Schlieper Georg Rainier, Schlack Wolfgang, Schrader Jürgen, Decking Ulrich K. M. Myocardial proteome analysis reveals reduced NOS inhibition and enhanced glycolytic capacity in areas of low local blood flow FASEB journal 2002;16 (6):628-630 [PubMed]
  • Preckel B., Müllenheim J., Schlack W. Myokardprotektion durch Inhalationsanästhetika Anaesthesiologie und Reanimation 2002;27 (5):116-123 [PubMed]
  • Preckel Benedikt, Ebel Dirk, Müllenheim Jost, Frässdorf Jan, Thämer Volker, Schlack Wolfgang The direct myocardial effects of xenon in the dog heart in vivo Anesthesia and analgesia 2002;94 (3):545-51; table of contents [PubMed]
  • Picker O., Schindler A. W., Schwarte L. A., Preckel B., Schlack W., Scheeren T. W. L., Thämer V. Xenon increases total body oxygen consumption during isoflurane anaesthesia in dogs British journal of anaesthesia 2002;88 (4):546-554 [PubMed]
  • Preckel B., Schlack W., Heibel T., Rütten H. Xenon produces minimal haemodynamic effects in rabbits with chronically compromised left ventricular function British journal of anaesthesia 2002;88 (2):264-269 [PubMed]

2001

  • Müllenheim J., Schlack W., Frässdorf J., Heinen A., Preckel B., Thämer V. Additive protective effects of late and early ischaemic preconditioning are mediated by the opening of KATP channels in vivo Pflugers Archiv 2001;442 (2):178-187 [PubMed]
  • Heck Z., Stegmann J. U., Lorenz C., Heck M., Schlack W. Akzeptanz der Präoxygenierung in der klinischen routine Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie 2001;36 (8):471-475 [PubMed]
  • Martini N., Preckel B., Thämer V., Schlack W. Can isoflurane mimic ischaemic preconditioning in isolated rat heart? British journal of anaesthesia 2001;86 (2):269-271 [PubMed]
  • Molojavyi A., Preckel B., Comfère T., Müllenheim J., Thämer V., Schlack W. Effects of ketamine and its isomers on ischemic preconditioning in the isolated rat heart Anesthesiology 2001;94 (4):623-9; discussion 5A-6A [PubMed]
  • Schlack W., Heck Z. Is a single vital capacity breath a suitable method for preoxygenation? Canadian journal of anaesthesia = Journal canadien d'anesthésie 2001;48 (4):423-424 [PubMed]
  • Müllenheim J., Frässdorf J., Preckel B., Thämer V., Schlack W. Ketamine, but not S(+)-ketamine, blocks ischemic preconditioning in rabbit hearts in vivo Anesthesiology 2001;94 (4):630-636 [PubMed]
  • Müllenheim J., Rulands R., Wietschorke T., Frässdorf J., Preckel B., Schlack W. Late preconditioning is blocked by racemic ketamine, but not by S(+)-ketamine Anesthesia and analgesia 2001;93 (2):265-70, 1st contents page [PubMed]
  • Ebel D., Lipfert P., Frässdorf J., Preckel B., Müllenheim J., Thämer V., Schlack W. Lidocaine reduces ischaemic but not reperfusion injury in isolated rat heart British journal of anaesthesia 2001;86 (6):846-852 [PubMed]
  • Schlack W., Heck Z., Lorenz C. Mask tolerance and preoxygenation: a problem for anesthesiologists but not for patients Anesthesiology 2001;94 (3):546 [PubMed]
  • Obal D., Preckel B., Scharbatke H., Müllenheim J., Höterkes F., Thämer V., Schlack W. One MAC of sevoflurane provides protection against reperfusion injury in the rat heart in vivo British journal of anaesthesia 2001;87 (6):905-911 [PubMed]
  • Müllenheim J., Molojavyi A., Preckel B., Thämer V., Schlack W. Thiopentone does not block ischemic preconditioning in the isolated rat heart Canadian journal of anaesthesia = Journal canadien d'anesthésie 2001;48 (8):784-789 [PubMed]

2000

  • Preckel B., Schlack W., Comfère T., Thämer V. Effect of dantrolene in an in vivo and in vitro model of myocardial reperfusion injury Acta anaesthesiologica Scandinavica 2000;44 (2):194-201 [PubMed]
  • Loer S. A., Schlack W., Ebel D., Tarnow J. Effects of partial liquid ventilation on regional pulmonary blood flow distribution of isolated rabbit lungs Critical care medicine 2000;28 (5):1522-1525 [PubMed]
  • Schlack W., Dinter W. Haemodynamic effects of a left stellate ganglion block in ASA I patients. An echocardiographic study European journal of anaesthesiology 2000;17 (2):79-84 [PubMed]
  • Preckel B., Schlack W., Gonzàlez M., Obal D., Barthel H., Thämer V. Influence of the angiotensin II AT1 receptor antagonist irbesartan on ischemia/reperfusion injury in the dog heart Basic research in cardiology 2000;95 (5):404-412 [PubMed]
  • Müllenheim J., Preckel B., Obal D., Heiderhoff M., Hoff J., Thämer V., Schlack W. Left stellate ganglion block has only small effects on left ventricular function in awake dogs before and after induction of heart failure Anesthesia and analgesia 2000;91 (4):787-792 [PubMed]
  • Preckel B., Müllenheim J., Moloschavij A., Thämer V., Schlack W. Xenon administration during early reperfusion reduces infarct size after regional ischemia in the rabbit heart in vivo Anesthesia and analgesia 2000;91 (6):1327-1332 [PubMed]

1999

  • Preckel B., Thämer V., Schlack W. Beneficial effects of sevoflurane and desflurane against myocardial reperfusion injury after cardioplegic arrest Canadian journal of anaesthesia = Journal canadien d'anesthésie 1999;46 (11):1076-1081 [PubMed]
  • Ebel D., Schlack W., Comfère T., Preckel B., Thämer V. Effect of propofol on reperfusion injury after regional ischaemia in the isolated rat heart British journal of anaesthesia 1999;83 (6):903-908 [PubMed]
  • Schlack W. Untersuchungen über die Wirkungen zervikothorakaler Sympathikusblockaden auf die Funktion des linken Ventrikels Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie 1999;34 (8):458-462 [PubMed]

1998

  • Schneider T., Drescher W., Becker C., Fink B., Schlack W., Sager M., Assheuer J., Rüther W. Der Einfluss von Bradykinin auf Druckänderungen in der Femurkopfepiphyse--eine experimentelle und kernspintomographische Studie Zeitschrift für Orthopädie und ihre Grenzgebiete 1998;136 (5):439-443 [PubMed]
  • Preckel B., Schlack W., Obal D., Barthel H., Ebel D., Grunert S., Thämer V. Effect of acidotic blood reperfusion on reperfusion injury after coronary artery occlusion in the dog heart Journal of cardiovascular pharmacology 1998;31 (2):179-186 [PubMed]
  • Schlack W., Ebel D., Grunert S., Halilović S., Meyer O., Thämer V. Effect of heart rate reduction by 4-(N-ethyl-N-phenyl-amino)-1,2-dimethyl-6-(methylamino)pyrimidinium chloride on infarct size in dog Arzneimittel-Forschung 1998;48 (1):26-33 [PubMed]
  • Preckel B., Schlack W., Comfère T., Obal D., Barthel H., Thämer V. Effects of enflurane, isoflurane, sevoflurane and desflurane on reperfusion injury after regional myocardial ischaemia in the rabbit heart in vivo British journal of anaesthesia 1998;81 (6):905-912 [PubMed]
  • Schlack W., Preckel B., Stunneck D., Thämer V. Effects of halothane, enflurane, isoflurane, sevoflurane and desflurane on myocardial reperfusion injury in the isolated rat heart British journal of anaesthesia 1998;81 (6):913-919 [PubMed]
  • Preckel B., Schlack W., Thämer V. Enflurane and isoflurane, but not halothane, protect against myocardial reperfusion injury after cardioplegic arrest with HTK solution in the isolated rat heart Anesthesia and analgesia 1998;87 (6):1221-1227 [PubMed]
  • Schneider T., Drescher W., Becker C., Schlack W., Sager M., Assheuer J., Rüther W. The impact of vasoactive substances on intraosseous pressure and blood flow alterations in the femoral head: a study based on magnetic resonance imaging Archives of orthopaedic and trauma surgery 1998;118 (1-2):45-49 [PubMed]

1997

  • Thämer V., Grunert S., Bier F., Schlack W. Einfluss von Magnesium auf die Infarktgrösse nach einer Koronarokklusion. Tierexperimentalle Untersuchungen Herz 1997;22 (Suppl. 1):35-39 [PubMed]
  • Siegmund B., Schlack W., Ladilov Y. V., Balser C., Piper H. M. Halothane protects cardiomyocytes against reoxygenation-induced hypercontracture Circulation 1997;96 (12):4372-4379 [PubMed]
  • Schlack W., Preckel B., Barthel H., Obal D., Thämer V. Halothane reduces reperfusion injury after regional ischaemia in the rabbit heart in vivo British journal of anaesthesia 1997;79 (1):88-96 [PubMed]
  • Preckel B., Kojda G., Schlack W., Ebel D., Kottenberg K., Noack E., Thämer V. Inotropic effects of glyceryl trinitrate and spontaneous NO donors in the dog heart Circulation 1997;96 (8):2675-2682 [PubMed]
  • Schlack W., Thämer V. Thoracic epidural anesthesia reduces the severity of myocardial ischemia in conscious dogs Anesthesia and analgesia 1997;85 (2):465-466 [PubMed]

1996

  • Schäfer S., Schlack W., Kelm M., Deussen A., Strauer B. E. Characterisation of left ventricular relaxation in the isolated guinea pig heart Research in experimental medicine. Zeitschrift für die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie 1996;196 (5):261-273 [PubMed]
  • Schlack W., Hollmann M., Stunneck J., Thämer V. Effect of halothane on myocardial reoxygenation injury in the isolated rat heart British journal of anaesthesia 1996;76 (6):860-867 [PubMed]
  • Schlack W., Ebel D., Thämer V. Effect of inotropic stimulation on the synchrony of left ventricular wall motion in a dog model of myocardial stunning Acta anaesthesiologica Scandinavica 1996;40 (5):621-630 [PubMed]
  • Schlack W., Thämer V. Unilateral changes of sympathetic tone to the heart impair left ventricular function Acta anaesthesiologica Scandinavica 1996;40 (2):262-271 [PubMed]

1995

  • Schlack W., Bier F., Schäfer M., Uebing A., Schäfer S., Borchard U., Thämer V. Intracoronary magnesium is not protective against acute reperfusion injury in the regional ischaemic-reperfused dog heart European journal of clinical investigation 1995;25 (7):501-509 [PubMed]
  • Schlack W., Uebing A., Schäfer M., Bier F., Grunert S., Ebel D., Piper H. M., Thämer V. Intracoronary SIN-1C during reperfusion reduces infarct size in dog Journal of cardiovascular pharmacology 1995;25 (3):424-431 [PubMed]

1994

  • Schlack W., Schäfer S., Thämer V. Left stellate ganglion block impairs left ventricular function Anesthesia and analgesia 1994;79 (6):1082-1088 [PubMed]
  • Schlack W., Schäfer S., Thämer V. Papaverine and regional myocardial function Cardiovascular research 1994;28 (3):434 [PubMed]
  • Schlack W., Uebing A., Schäfer M., Bier F., Schäfer S., Piper H. M., Thämer V. Regional contractile blockade at the onset of reperfusion reduces infarct size in the dog heart Pflugers Archiv 1994;428 (2):134-141 [PubMed]

1993

  • Schlack W., Schäfer M., Uebing A., Schäfer S., Borchard U., Thämer V. Adenosine A2-receptor activation at reperfusion reduces infarct size and improves myocardial wall function in dog heart Journal of cardiovascular pharmacology 1993;22 (1):89-96 [PubMed]

1988

  • Loos U., Oehr P., Genske F., Schlack W. Diagnostische Aussagemöglichkeiten der Tumormarker CEA und TPA in der bronchoalveolären Lavage Praxis und Klinik der Pneumologie 1988;42 (Suppl. 1):235-237 [PubMed]
  • Loos U., Disse B., Eberhardt H., Schlack W. Zelluläre und humorale Komponenten in der bronchoalveolären Lavage aus verschiedenen Lungensegmenten Praxis und Klinik der Pneumologie 1988;42 (3):89-91 [PubMed]