Prof. PhD A.K. Groen publications

foto

Publications Prof. PhD A.K. Groen

Positions
Full Professor, Research Associate
Main activities
Education, Research
Specialisation
Systems Medicine
Focus of research

An integrated approach to study cardiometabolism

2020

  • Roscam Abbing Reinout L. P., Slijepcevic Davor, Donkers Joanne M., Havinga Rick, Duijst Suzanne, Paulusma Coen C., Kuiper Johan, Kuipers Folkert, Groen Albert K., Oude Elferink Ronald P. J., van de Graaf Stan F. J. Blocking Sodium-Taurocholate Cotransporting Polypeptide Stimulates Biliary Cholesterol and Phospholipid Secretion in Mice Hepatology (Baltimore, Md.) 2020;71 (1):247-258 [PubMed]
  • Hartstra Annick V., de Groot Pieter F., Mendes Bastos Diogo, Levin Evgeni, Serlie Mireille J., Soeters Maarten R., Pekmez Ceyda T., Dragsted Lars O., Ackermans Mariette T., Groen Albert K., Nieuwdorp Max Correlation of plasma metabolites with glucose and lipid fluxes in human insulin resistance Obesity Science and Practice 2020
  • Meessen Emma C. E., Sips Fianne L. P., Eggink Hannah M., Koehorst Martijn, Romijn Johannes A., Groen Albert K., van Riel Natal A. W., Soeters Maarten R. Model-based data analysis of individual human postprandial plasma bile acid responses indicates a major role for the gallbladder and intestine Physiological reports 2020;8 (5) [PubMed]

2019

  • Zhang Xiang, van den Munckhof Inge C. L., Rutten Joost H. W., Netea Mihai G., Groen Albert K., Zwinderman Aeilko H. Association of hemoglobin A1C with circulating metabolites in Dutch with European, African Surinamese and Ghanaian background NUTRITION & DIABETES 2019;9 (1) [PubMed]
  • van der Geest Rick, van der Sluis Ronald J., Groen Albert K., van Eck Miranda, Hoekstra Menno Cholestasis-associated glucocorticoid overexposure does not increase atherogenesis Journal of endocrinology 2019;242 (2):1-12 [PubMed]
  • Bogie Jeroen, Hoeks Cindy, Schepers Melissa, Tiane Assia, Cuypers Ann, Leijten Frank, Chintapakorn Yupyn, Suttiyut Thiti, Pornpakakul Surachai, Struik Dicky, Kerksiek Anja, Liu Hong-Bing, Hellings Niels, Martinez-Martinez Pilar, Jonker Johan W., Dewachter Ilse, Sijbrands Eric, Walter Jochen, Hendriks Jerome, Groen Albert, Staels Bart, Lütjohann Dieter, Vanmierlo Tim, Mulder Monique Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer’s disease mouse model Scientific reports 2019;9 (1) [PubMed]
  • de Groot Pieter, Scheithauer Torsten, Bakker Guido J., Prodan Andrei, Levin Evgeni, Khan Muhammad Tanweer, Herrema Hilde, Ackermans Mariette, Serlie Mireille J. M., de Brauw Maurits, Levels Johannes H. M., Sales Amber, Gerdes Victor E., Ståhlman Marcus, Schimmel Alinda W. M., Dallinga-Thie Geesje, Bergman Jacques Jghm, Holleman Frits, Hoekstra Joost B. L., Groen Albert, Bäckhed Fredrik, Nieuwdorp Max Donor metabolic characteristics drive effects of faecal microbiota transplantation on recipient insulin sensitivity, energy expenditure and intestinal transit time Gut 2019 [PubMed]
  • van de Peppel Ivo P., Bertolini Anna, van Dijk Theo H., Groen Albert K., Jonker Johan W., Verkade Henkjan J. Efficient reabsorption of transintestinally excreted cholesterol is a strong determinant for cholesterol disposal in mice Journal of lipid research 2019;60 (9):1562-1572 [PubMed]
  • Saeed Ali, Yang Jing, Heegsma Janette, Groen Albert K., van Mil Saskia W. C., Paulusma Coen C., Zhou Lu, Wang Bangmao, Faber Klaas Nico Farnesoid X receptor and bile acids regulate vitamin A storage Scientific reports 2019;9 (1) [PubMed]
  • van Zutphen Tim, Stroeve Johanna H. M., Yang Jiufang, Bloks Vincent W., Jurdzinski Angelika, Roelofsen Han, Huijkman Nicolette C. A., van Dijk Theo H., Vonk Roel J., van Deursen Jan, Staels Bart, Groen Albert K., Kuipers Folkert FXR overexpression alters adipose tissue architecture in mice and limits its storage capacity leading to metabolic derangements Journal of lipid research 2019;60 (9):1547-1561 [PubMed]
  • Pereira João, Groen Albert K., Stroes Erik S. G., Levin Evgeni Graph space embeddingin: Sarit Kraus, editors. Proceedings of the 28th International Joint Conference on Artificial Intelligence, IJCAI 2019. International Joint Conferences on Artificial Intelligence; 2019. p. 3253-3259
  • Nascimento Emmani B. M., Konings Maurice, Schaart Gert, Groen Albert K., Lütjohann Dieter, van Marken Lichtenbelt Wouter D., Schrauwen Patrick, Plat Jogchum In vitro effects of sitosterol and sitostanol on mitochondrial respiration in human brown adipocytes, myotubes and hepatocytes European journal of nutrition 2019 [PubMed]
  • Bakker Guido J., Schnitzler Johan G., Bekkering Siroon, de Clercq Nicolien C., Koopen Annefleur M., Hartstra Annick V., Meessen Emma C. E., Scheithauer Torsten P., Winkelmeijer Maaike, Dallinga-Thie Geesje M., Cani Patrice D., Kemper Elles Marleen, Soeters Maarten R., Kroon Jeffrey, Groen Albert K., van Raalte Daniël H., Herrema Hilde, Nieuwdorp Max Oral vancomycin treatment does not alter markers of postprandial inflammation in lean and obese subjects Physiological reports 2019;7 (16) [PubMed]
  • Plat J., Baumgartner S., Vanmierlo T., Lütjohann D., Calkins K. L., Burrin D. G., Guthrie G., Thijs C., te Velde A. A., Vreugdenhil A. C. E., Sverdlov R., Garssen J., Wouters K., Trautwein E. A., Wolfs T. G., van Gorp C., Mulder M. T., Riksen N. P., Groen A. K., Mensink R. P. Plant-based sterols and stanols in health & disease: "Consequences of human development in a plant-based environment?" Progress in lipid research 2019;74:87-102 [PubMed]
  • Zhang Xiang, Nieuwdorp Max, Groen Albert K., Zwinderman Aeiko H. Statistical evaluation of diet-microbe associations BMC microbiology 2019;19 (1) [PubMed]
  • Zhang Xiang Studies with high dimensional omics data: Pathways, networks and statistical analysis 2019. 158p. ISBN 9789463754118. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Groen A. K. , Zwinderman A. H.)
  • de Clercq Nicolien C., Frissen Myrthe N., Levin Evgeni, Davids Mark, Hartman Jorn, Prodan Andrei, Herrema H., Groen Albert K., Romijn Johannes A., Nieuwdorp Max The effect of having Christmas dinner with in-laws on gut microbiota composition Human Microbiome Journal 2019;13
  • Grefhorst Aldo, Verkade Henkjan J., Groen Albert K. The TICE Pathway: Mechanisms and Lipid-Lowering Therapies Methodist DeBakey cardiovascular journal 2019;15 (1):70-76 [PubMed]
  • de Clercq Nicolien C., Frissen Myrthe N., Davids Mark, Groen Albert K., Nieuwdorp Max Weight Gain after Fecal Microbiota Transplantation in a Patient with Recurrent Underweight following Clinical Recovery from Anorexia Nervosa Psychotherapy and psychosomatics 2019;88 (1):58-60 [PubMed]

2018

  • van Stee Mariël F., de Graaf Albert A., Groen Albert K. Actions of metformin and statins on lipid and glucose metabolism and possible benefit of combination therapy Cardiovascular diabetology 2018;17 (1) [PubMed]
  • Li Zhuang, Yi Chun-Xia, Katiraei Saeed, Kooijman Sander, Zhou Enchen, Chung Chih Kit, Gao Yuanqing, van den Heuvel José K., Meijer Onno C., Berbée Jimmy F. P., Heijink Marieke, Giera Martin, Willems van Dijk Ko, Groen Albert K., Rensen Patrick C. N., Wang Yanan Butyrate reduces appetite and activates brown adipose tissue via the gut-brain neural circuit Gut 2018;67 (7):1269-1279 [PubMed]
  • de Boer Jan Freark, Kuipers Folkert, Groen Albert K. Cholesterol Transport Revisited: A New Turbo Mechanism to Drive Cholesterol Excretion Trends in endocrinology and metabolism: TEM 2018;29 (2):123-133 [PubMed]
  • Eggink Hannah M., Tambyrajah Lauren L., van den Berg Rosa, Mol Isabel M., van den Heuvel Jose K., Koehorst Martijn, Groen Albert K., Boelen Anita, Kalsbeek Andries, Romijn Johannes A., Rensen Patrick C. N., Kooijman Sander, Soeters Maarten R. Chronic infusion of taurolithocholate into the brain increases fat oxidation in mice Journal of endocrinology 2018;236 (2):85-97 [PubMed]
  • Deschasaux M. lanie, Bouter Kristien E., Prodan Andrei, Levin Evgeni, Groen Albert K., Herrema Hilde, Tremaroli Valentina, Bakker Guido J., Attaye Ilias, Pinto-Sietsma Sara-Joan, van Raalte Daniel H., Snijder Marieke B., Nicolaou Mary, Peters Ron, Zwinderman Aeilko H., Bäckhed Fredrik, Nieuwdorp Max Depicting the composition of gut microbiota in a population with varied ethnic origins but shared geography Nature medicine 2018;24 (10):1526-1531 [PubMed]
  • Bouter K. E. C., Bakker G. J., Levin E., Hartstra A. V., Kootte R. S., Udayappan S. D., Katiraei S., Bahler L., Gilijamse P. W., Tremaroli V., Stahlman M., Holleman F., van Riel N. A. W., Verberne H. J., Romijn J. A., Dallinga-Thie G. M., Serlie M. J., Ackermans M. T., Kemper E. M., Willems van Dijk K., Backhed F., Groen A. K., Nieuwdorp M. Differential metabolic effects of oral butyrate treatment in lean versus metabolic syndrome subjects article Clinical and translational gastroenterology 2018;9 (5) [PubMed]
  • Imangaliyev Sultan, Prodan Andrei, Nieuwdorp Max, Groen Albert K., van Riel Natal A. W., Levin Evgeni Domain intelligible models Methods (San Diego, Calif.) 2018;149:69-73 [PubMed]
  • van Baar Annieke C. G., Prodan Andrei, Wahlgren Camilla D., Poulsen Steen S., Knop Filip K., Groen Albert K., Bergman Jacques J., Nieuwdorp Max, Levin Evgeni Duodenal L cell density correlates with features of metabolic syndrome and plasma metabolites Endocrine connections 2018;7 (5):673-680 [PubMed]
  • Smits Loek P., Kootte Ruud S., Levin Evgeni, Prodan Andrei, Fuentes Susana, Zoetendal Erwin G., Wang Zeneng, Levison Bruce S., Cleophas Maartje C. P., Kemper E. Marleen, Dallinga-Thie Geesje M., Groen Albert K., Joosten Leo A. B., Netea Mihai G., Stroes Erik S. G., de Vos Willem M., Hazen Stanley L., Nieuwdorp Max Effect of vegan fecal microbiota transplantation on carnitine- and choline-derived trimethylamine-N-oxide production and vascular inflammation in patients with metabolic syndrome Journal of the American Heart Association 2018;7 (7) [PubMed]
  • Rau Monika, Rehman Ateequr, Dittrich Marcus, Groen Albert K., Hermanns Heike M., Seyfried Florian, Beyersdorf Niklas, Dandekar Thomas, Rosenstiel Philip, Geier Andreas Fecal SCFAs and SCFA-producing bacteria in gut microbiome of human NAFLD as a putative link to systemic T-cell activation and advanced disease United European gastroenterology journal 2018;6 (10):1496-1507 [PubMed]
  • Groen Robin N., de Clercq Nicolien C., Nieuwdorp Max, Hoenders H. J. Rogier, Groen Albert K. Gut microbiota, metabolism and psychopathology: A critical review and novel perspectives Critical reviews in clinical laboratory sciences 2018;55 (4):283-293 [PubMed]
  • Zhang Xiang, Mardinoglu Adil, Joosten Leo A. B., Kuivenhoven Jan A., Li Yang, Netea Mihai G., Groen Albert K. Identification of discriminating metabolic pathways and metabolites in human PBMCs stimulated by various pathogenic agents Frontiers in physiology 2018;9 (FEB) [PubMed]
  • Sips Fianne L. P., Eggink Hannah M., Hilbers Peter A. J., Soeters Maarten R., Groen Albert K., van Riel Natal A. W. In silico analysis identifies intestinal transit as a key determinant of systemic bile acid metabolism Frontiers in physiology 2018;9 (JUN) [PubMed]
  • Rozendaal Yvonne J. W., Wang Yanan, Paalvast Yared, Tambyrajah Lauren L., Li Zhuang, Willems van Dijk Ko, Rensen Patrick C. N., Kuivenhoven Jan A., Groen Albert K., Hilbers Peter A. J., van Riel Natal A. W. In vivo and in silico dynamics of the development of Metabolic Syndrome PLoS computational biology 2018;14 (6) [PubMed]
  • van der Tuin Sam J. L., Li Zhuang, Berbée Jimmy F. P., Verkouter Inge, Ringnalda Linda E., Neele Annette E., van Klinken Jan B., Rensen Sander S., Fu Jingyuan, de Winther Menno P. J., Groen Albert K., Rensen Patrick C. N., van Dijk Ko Willems, Wang Yanan Lipopolysaccharide lowers cholesteryl ester transfer protein by activating F4/80+Clec4f+Vsig4+Ly6C- Kupffer Cell Subsets Journal of the American Heart Association 2018;7 (6) [PubMed]
  • Stolle Sarah, Ciapaite Jolita, Reijne Aaffien C., Talarovicova Alzbeta, Wolters Justina C., Aguirre-Gamboa Raúl, van der Vlies Pieter, de lange Kim, Neerincx Pieter B., van der Vries Gerben, Deelen Patrick, Swertz Morris A., Li Yang, Bischoff Rainer, Permentier Hjalmar P., Horvatovitch Peter L., Groen Albert K., van Dijk Gertjan, Reijngoud Dirk-Jan, Bakker Barbara M. Running-wheel activity delays mitochondrial respiratory flux decline in aging mouse muscle via a post-transcriptional mechanism Aging cell 2018;17 (1):UNSP e12700 [PubMed]
  • van Baar A. C. G., Nieuwdorp M., Holleman F., Soeters M. R., Groen A. K., Bergman Jacques J. G. H. M. The Duodenum harbors a Broad Untapped Therapeutic Potential Gastroenterology 2018;154 (4):773-777 [PubMed]
  • Chevre Raphael, Trigueros-Motos Laia, Castaño David, Chua Tricia, Corlianò Maria, Patankar Jay V., Sng Lareina, Sim Lauren, Juin Tan Liang, Carissimo Guillaume, Ng Lisa F. P., Yi Cheryl Neo Jia, Eliathamby Chelsea Chandani, Groen Albert K., Hayden Michael R., Singaraja Roshni R. Therapeutic modulation of the bile acid pool by Cyp8b1 knockdown protects against nonalcoholic fatty liver disease in mice FASEB journal 2018;32 (7):3792-3802 [PubMed]
  • Eggink Hannah M., van Nierop F. Samuel, Schooneman Marieke G., Boelen Anita, Kalsbeek Andries, Koehorst Martijn, ten Have Gabriella A. M., de Brauw L. Maurits, Groen Albert K., Romijn Johannes A., Deutz Nicolaas E. P., Soeters Maarten R. Transhepatic bile acid kinetics in pigs and humans Clinical nutrition (Edinburgh, Scotland) 2018;37 (4):1406-1414 [PubMed]
  • Reeskamp Laurens F., Meessen Emma C. E., Groen Albert K. Transintestinal cholesterol excretion in humans Current opinion in lipidology 2018;29 (1):10-17 [PubMed]
  • Zhang Xiang, Rimbert Antoine, Balder Willem, Zwinderman Aeilko Having, Kuivenhoven Jan Albert, Dallinga-Thie Geesje Margaretha, Groen Albert Kornelis Use of plasma metabolomics to analyze phenotype-genotype relationships in young hypercholesterolemic females Journal of lipid research 2018;59 (11):2174-2180 [PubMed]

2017

  • Groen Albert K., Nieuwdorp Max An evaluation of the therapeutic potential of fecal microbiota transplantation to treat infectious and metabolic diseases EMBO molecular medicine 2017;9 (1):1-3 [PubMed]
  • Janssen Aafke W. F., Dijk Wieneke, Boekhorst Jos, Kuipers Folkert, Groen Albert K., Lukovac Sabina, Hooiveld Guido J. E. J., Kersten Sander ANGPTL4 promotes bile acid absorption during taurocholic acid supplementation via a mechanism dependent on the gut microbiota BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS 2017;1862 (10 Part A):1056-1067 [PubMed]
  • Kuipers Folkert, Groen Albert K. An unexpected role for bile acid synthesis in adaptation to low temperature Nature medicine 2017;23 (7):800-802 [PubMed]
  • Hoeke Geerte, Wang Yanan, van Dam Andrea D., Mol Isabel M., Gart Eveline, Klop Henk G., van den Berg Susan M., Pieterman Elsbet H., Princen Hans M. G., Groen Albert K., Rensen Patrick C. N., Berbée Jimmy F. P., Boon Mariëtte R. Atorvastatin accelerates clearance of lipoprotein remnants generated by activated brown fat to further reduce hypercholesterolemia and atherosclerosis Atherosclerosis 2017;267:116-126 [PubMed]
  • Eggink Hannah M., Oosterman Johanneke E., de Goede Paul, de Vries Emmely M., Foppen Ewout, Koehorst Martijn, Groen Albert K., Boelen Anita, Romijn Johannes A., la Fleur Susanne E., Soeters Maarten R., Kalsbeek Andries Complex interaction between circadian rhythm and diet on bile acid homeostasis in male rats Chronobiology international 2017;34 (10):1339-1353 [PubMed]
  • Paalvast Yared, de Boer Jan Freark, Groen Albert K. Developments in intestinal cholesterol transport and triglyceride absorption Current opinion in lipidology 2017;28 (3):248-254 [PubMed]
  • Kuiken Nicoline S. S., Rings Edmond H. H. M., Havinga Rick, van der Aa Stijn A. J., Groen Albert K., Tissing Wim J. E. Effect of Oral Insulin on the Severity and Recovery of Methotrexate-Induced Gastrointestinal Mucositis in the Rat Journal of pediatric gastroenterology and nutrition 2017;64 (2):e27-e32 [PubMed]
  • Hulzebos Christian V., van Zoonen Anne G. J. F., Hulscher Jan B. F., Schat Trijntje E., Kooi Elisabeth M. W., Koehorst Martijn, Boverhof Renze, Krabbe Paul F. M., Groen Albert K., Verkade Henkjan J. Fecal Bile Salts and the Development of Necrotizing Enterocolitis in Preterm Infants PLoS ONE 2017;12 (1):e0168633 [PubMed]
  • de Clercq Nicolien C., Frissen Myrthe N., Groen Albert K., Nieuwdorp Max Gut Microbiota and the Gut-Brain Axis: New Insights in the Pathophysiology of Metabolic Syndrome Psychosomatic medicine 2017;79 (8):874-879 [PubMed]
  • Kootte Ruud S., Levin Evgeni, Salojärvi Jarkko, Smits Loek P., Hartstra Annick V., Udayappan Shanti D., Hermes Gerben, Bouter Kristien E., Koopen Annefleur M., Holst Jens J., Knop Filip K., Blaak Ellen E., Zhao Jing, Smidt Hauke, Harms Amy C., Hankemeijer Thomas, Bergman Jacques J. G. H. M., Romijn Hans A., Schaap Frank G., Olde Damink Steven W. M., Ackermans Mariette T., Dallinga-Thie Geesje M., Zoetendal Erwin, de Vos Willem M., Serlie Mireille J., Stroes Erik S. G., Groen Albert K., Nieuwdorp Max Improvement of Insulin Sensitivity after Lean Donor Feces in Metabolic Syndrome Is Driven by Baseline Intestinal Microbiota Composition Cell metabolism 2017;26 (4):611-+ [PubMed]
  • de Boer Jan Freark, Schonewille Marleen, Boesjes Marije, Wolters Henk, Bloks Vincent W., Bos Trijnie, van Dijk Theo H., Jurdzinski Angelika, Boverhof Renze, Wolters Justina C., Kuivenhoven Jan A., van Deursen Jan M., Oude Elferink Ronald P. J., Moschetta Antonio, Kremoser Claus, Verkade Henkjan J., Kuipers Folkert, Groen Albert K. Intestinal Farnesoid X Receptor Controls Transintestinal Cholesterol Excretion in Mice Gastroenterology 2017;152 (5):1126-1138.e6 [PubMed]
  • Udayappan Shanthadevi D., Kovatcheva-Datchary Petia, Bakker Guido J., Havik Stefan R., Herrema Hilde, Cani Patrice D., Bouter Kristien E., Belzer Clara, Witjes Julia J., Vrieze Anne, de Sonnaville Noor, Chaplin Alice, van Raalte Daniel H., Aalvink Steven, Dallinga-Thie Geesje M., Heilig Hans G. H. J., Bergström Göran, van der Meij Suzan, van Wagensveld Bart A., Hoekstra Joost B. L., Holleman Frits, Stroes Erik S. G., Groen Albert K., Bäckhed Fredrik, de Vos Willem M., Nieuwdorp Max Intestinal Ralstonia pickettii augments glucose intolerance in obesity PLoS ONE 2017;12 (11):e0181693 [PubMed]
  • Paalvast Yared, Gerding Albert, Wang Yanan, Bloks Vincent W., van Dijk Theo H., Havinga Rick, Willems van Dijk Ko, Rensen Patrick C. N., Bakker Barbara M., Kuivenhoven Jan Albert, Groen Albert K. Male apoE*3-Leiden.CETP mice on high-fat high-cholesterol diet exhibit a biphasic dyslipidemic response, mimicking the changes in plasma lipids observed through life in men Physiological reports 2017;5 (19) [PubMed]
  • Hijmans Brenda S. Metabolic adaptations in models of fatty liver disease: Of mice and math 2017. ISBN 9789036795005. [UvA Dissertations Online] University of Groningen: Faculty of Medicine. (Supervisors: Groen A. K., Reijngoud D. J.; Co-supervisor: Oosterveer M. H.)
  • Schnitzler Johan G., Bernelot Moens Sophie J., Tiessens Feiko, Bakker Guido J., Dallinga-Thie Geesje M., Groen Albert K., Nieuwdorp Max, Stroes Erik S. G., Kroon Jeffrey Nile Red Quantifier: a novel and quantitative tool to study lipid accumulation in patient- derived circulating monocytes using confocal microscopy Journal of lipid research 2017;58 (11):2210-2219 [PubMed]
  • Kuiken Nicoline S. S. Prevention and care of chemotherapy-induced gastrointestinal mucositis 2017. ISBN 9789036797504. [UvA Dissertations Online] University of Groningen,: Paediatrics, General Practice-Department. (Supervisors: Rings E. H. H. M., Groen A. K.; Co-supervisor: Tissing W. J. E.)
  • Zweers Serge J., de Vries Elisabeth M., Lenicek Martin, Tolenaars Dagmar, de Waart D. Rudi, Koelfat Kiran V. K., Groen Albert K., Olde Damink Steven W. M., Beuers Ulrich, Ponsioen Cyriel, Jansen Peter L. M., Schaap Frank G. Prolonged fibroblast growth factor 19 response in patients with primary sclerosing cholangitis after an oral chenodeoxycholic acid challenge Hepatology international 2017;11 (1):132-140 [PubMed]
  • Dugardin Camille, Briand Olivier, Touche Véronique, Schonewille Marleen, Moreau François, Le May Cédric, Groen Albert K., Staels Bart, Lestavel Sophie Retrograde cholesterol transport in the human Caco-2/TC7 cell line: a model to study trans-intestinal cholesterol excretion in atherogenic and diabetic dyslipidemia Acta diabetologica 2017;54 (2):191-199 [PubMed]
  • Bouter Kristien E., van Raalte Daniël H., Groen Albert K., Nieuwdorp Max Role of the Gut Microbiome in the Pathogenesis of Obesity and Obesity-Related Metabolic Dysfunction Gastroenterology 2017;152 (7):1671-1678 [PubMed]
  • Kuiken Nicoline S. S., Rings Edmond H. H. M., Alffenaar Jan-Willem C., Havinga Rick, Jurdzinski Angelika, Groen Albert K., Tissing Wim J. E. Tumor Necrosis Factor-Alpha Inhibitor Etanercept Does Not Alter Methotrexate-Induced Gastrointestinal Mucositis in Rats Journal of pediatric gastroenterology and nutrition 2017;65 (2):e28-e34 [PubMed]

2016

  • Schonewille Marleen, de Boer Jan Freark, Groen Albert K. Bile salts in control of lipid metabolism Current opinion in lipidology 2016;27 (3):295-301 [PubMed]
  • Smits Mark M., Tonneijck Lennart, Muskiet Marcel H. A., Hoekstra Trynke, Kramer Mark H. H., Diamant Michaela, Nieuwdorp Max, Groen Albert K., Cahen Djuna L., van Raalte Daniël H. Biliary effects of liraglutide and sitagliptin, a 12-week randomized placebo-controlled trial in type 2 diabetes patients Diabetes, obesity & metabolism 2016;18 (12):1217-1225 [PubMed]
  • Bartuzi Paulina, Billadeau Daniel D., Favier Robert, Rong Shunxing, Dekker Daphne, Fedoseienko Alina, Fieten Hille, Wijers Melinde, Levels Johannes H., Huijkman Nicolette, Kloosterhuis Niels, Van der Molen Henk, Brufau Gemma, Groen Albert K., Elliott Alison M., Kuivenhoven Jan Albert, Plecko Barbara, Grangl Gernot, McGaughran Julie, Horton Jay D., Burstein Ezra, Hofker Marten H., van de Sluis Bart CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL Nature communications 2016;7:10961 [PubMed]
  • Schonewille Marleen Cholesterol, bile acid and triglyceride metabolism intertwined 2016. 147p. ISBN 9789036790055. [UvA Dissertations Online] University of Groningen: UMCG, Department of Pediatrics Center for Liver, Digestive and Metabolic Diseases. (Supervisor: Groen A. K.)
  • Marsch Elke, Demandt Jasper A. F., Theelen Thomas L., Tullemans Bibian M. E., Wouters Kristiaan, Boon Mariëtte R., van Dijk Theo H., Gijbels Marion J., Dubois Ludwig J., Meex Steven J. R., Mazzone Massimiliano, Hung Gene, Fisher Edward A., Biessen Erik A. L., Daemen Mat J. A. P., Rensen Patrick C. N., Carmeliet Peter, Groen Albert K., Sluimer Judith C. Deficiency of the oxygen sensor prolyl hydroxylase 1 attenuates hypercholesterolaemia, atherosclerosis, and hyperglycaemia European heart journal 2016;37 (39):2993-2997 [PubMed]
  • Stöger J. Lauran, Boshuizen Marieke C. S., Brufau Gemma, Gijbels Marion J. J., Wolfs Ine M. J., van der Velden Saskia, Pöttgens Chantal C. H., Vergouwe Monique N., Wijnands Erwin, Beckers Linda, Goossens Pieter, Kerksiek Anja, Havinga Rick, Müller Werner, Lütjohann Dieter, Groen Albert K., de Winther Menno P. J. Deleting myeloid IL-10 receptor signalling attenuates atherosclerosis in LDLR-/- mice by altering intestinal cholesterol fluxes Thrombosis and haemostasis 2016;116 (3):565-577 [PubMed]
  • Kuiken Nicoline S. S., Rings Edmond H. H. M., Havinga Rick, Groen Albert K., Tissing Wim J. E. Effect of minimal enteral feeding on recovery in a methotrexate-induced gastrointestinal mucositis rat model Supportive care in cancer 2016;24 (3):1357-1364 [PubMed]
  • Reijnders Dorien, Goossens Gijs H., Hermes Gerben D. A., Neis Evelien P. J. G., van der Beek Christina M., Most Jasper, Holst Jens J., Lenaerts Kaatje, Kootte Ruud S., Nieuwdorp Max, Groen Albert K., Olde Damink Steven W. M., Boekschoten Mark V., Smidt Hauke, Zoetendal Erwin G., Dejong Cornelis H. C., Blaak Ellen E. Effects of Gut Microbiota Manipulation by Antibiotics on Host Metabolism in Obese Humans: A Randomized Double-Blind Placebo-Controlled Trial Cell metabolism 2016;24 (1):63-74 [PubMed]
  • Reijnders Dorien, Goossens Gijs H., Hermes Gerben D. A., Neis Evelien P. J. G., van der Beek Christina M., Most Jasper, Holst Jens J., Lenaerts Kaatje, Kootte Ruud S., Nieuwdorp Max, Groen Albert K., Olde Damink Steven W. M., Boekschoten Mark V., Smidt Hauke, Zoetendal Erwin G., Dejong Cornelis H. C., Blaak Ellen E. Effects of Gut Microbiota Manipulation by Antibiotics on Host Metabolism in Obese Humans: A Randomized Double-Blind Placebo-Controlled Trial Cell metabolism 2016;24 (2):341 [PubMed]
  • van der Geest Rick, Ouweneel Amber B., van der Sluis Ronald J., Groen Albert K., van Eck Miranda, Hoekstra Menno Endogenous glucocorticoids exacerbate cholestasis-associated liver injury and hypercholesterolemia in mice Toxicology and applied pharmacology 2016;306:1-7 [PubMed]
  • de Clercq Nicolien C., Groen Albert K., Romijn Johannes A., Nieuwdorp Max Gut Microbiota in Obesity and Undernutrition Advances in nutrition 2016;7 (6):1080-1089 [PubMed]
  • Verhaag Esther M., Buist-Homan Manon, Koehorst Martijn, Groen Albert K., Moshage Han, Faber Klaas Nico Hormesis in Cholestatic Liver Disease; Preconditioning with Low Bile Acid Concentrations Protects against Bile Acid-Induced Toxicity PLoS ONE 2016;11 (3):e0149782 [PubMed]
  • Koopen Annefleur M., Groen Albert K., Nieuwdorp Max Human microbiome as therapeutic intervention target to reduce cardiovascular disease risk Current opinion in lipidology 2016;27 (6):615-622 [PubMed]
  • Zhang Ling, Voskuijl Wieger, Mouzaki Marialena, Groen Albert K., Alexander Jennifer, Bourdon Celine, Wang Alice, Versloot Christian J., Di Giovanni Valeria, Wanders Ronald J. A., Bandsma Robert Impaired Bile Acid Homeostasis in Children with Severe Acute Malnutrition PLoS ONE 2016;11 (5):e0155143 [PubMed]
  • Lee Sunjae, Zhang Cheng, Kilicarslan Murat, Piening Brian D., Bjornson Elias, Hallström Björn M., Groen Albert K., Ferrannini Ele, Laakso Markku, Snyder Michael, Blüher Matthias, Uhlen Mathias, Nielsen Jens, Smith Ulf, Serlie Mireille J., Boren Jan, Mardinoglu Adil Integrated Network Analysis Reveals an Association between Plasma Mannose Levels and Insulin Resistance Cell metabolism 2016;24 (1):172-184 [PubMed]
  • Briand Olivier, Touche Véronique, Colin Sophie, Brufau Gemma, Davalos Alberto, Schonewille Marleen, Bovenga Fabiola, Carrière Véronique, de Boer Jan Freark, Dugardin Camille, Riveau Béatrice, Clavey Véronique, Tailleux Anne, Moschetta Antonio, Lasunción Miguel A., Groen Albert K., Staels Bart, Lestavel Sophie Liver X Receptor Regulates Triglyceride Absorption Through Intestinal Down-regulation of Scavenger Receptor Class B, Type 1 Gastroenterology 2016;150 (3):650-658 [PubMed]
  • van Zutphen Tim, Ciapaite Jolita, Bloks Vincent W., Ackereley Cameron, Gerding Albert, Jurdzinski Angelika, de Moraes Roberta Allgayer, Zhang Ling, Wolters Justina C., Bischoff Rainer, Wanders Ronald J., Houten Sander M., Bronte-Tinkew Dana, Shatseva Tatiana, Lewis Gary F., Groen Albert K., Reijngoud Dirk-Jan, Bakker Barbara M., Jonker Johan W., Kim Peter K., Bandsma Robert H. J. Malnutrition-associated liver steatosis and ATP depletion is caused by peroxisomal and mitochondrial dysfunction Journal of hepatology 2016;65 (6):1198-1208 [PubMed]
  • Ronda Onne A. H. O., van Dijk Theo H., Verkade H. J., Groen Albert K. Measurement of Intestinal and Peripheral Cholesterol Fluxes by a Dual-Tracer Balance Method Current protocols in mouse biology 2016;6 (4):408-434 [PubMed]
  • Sachdev Vinay, Leopold Christina, Bauer Raimund, Patankar Jay V., Iqbal Jahangir, Obrowsky Sascha, Boverhof Renze, Doktorova Marcela, Scheicher Bernhard, Goeritzer Madeleine, Kolb Dagmar, Turnbull Andrew V., Zimmer Andreas, Hoefler Gerald, Hussain M. Mahmood, Groen Albert K., Kratky Dagmar Novel role of a triglyceride-synthesizing enzyme: DGAT1 at the crossroad between triglyceride and cholesterol metabolism BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 2016;1861 (9 Part A):1132-1141 [PubMed]
  • Udayappan Shanthadevi, Manneras-Holm Louise, Chaplin-Scott Alice, Belzer Clara, Herrema Hilde, Dallinga-Thie Geesje M., Duncan Silvia H., Stroes Erik S. G., Groen Albert K., Flint Harry J., Backhed Fredrik, de Vos Willem M., Nieuwdorp Max Oral treatment with Eubacterium hallii improves insulin sensitivity in db/db mice NPJ biofilms and microbiomes 2016;2:16009 [PubMed]
  • Schonewille Marleen, de Boer Jan Freark, Mele Laura, Wolters Henk, Bloks Vincent W., Wolters Justina C., Kuivenhoven Jan A., Tietge Uwe J. F., Brufau Gemma, Groen Albert K. Statins increase hepatic cholesterol synthesis and stimulate fecal cholesterol elimination in mice Journal of lipid research 2016;57 (8):1455-1464 [PubMed]
  • Acuña Mariana, González-Hódar Lila, Amigo Ludwig, Castro Juan, Morales M. Gabriela, Cancino Gonzalo I., Groen Albert K., Young Juan, Miquel Juan Francisco, Zanlungo Silvana Transgenic overexpression of Niemann-Pick C2 protein promotes cholesterol gallstone formation in mice Journal of hepatology 2016;64 (2):361-369 [PubMed]
  • Jakulj Lily, van Dijk Theo H., de Boer Jan Freark, Kootte Ruud S., Schonewille Marleen, Paalvast Yared, Boer Theo, Bloks Vincent W., Boverhof Renze, Nieuwdorp Max, Beuers Ulrich H. W., Stroes Erik S. G., Groen Albert K. Transintestinal Cholesterol Transport Is Active in Mice and Humans and Controls Ezetimibe-Induced Fecal Neutral Sterol Excretion Cell metabolism 2016;24 (6):783-794 [PubMed]
  • Groen Albert K. Unexpected cholesterol gallstones Hepatology (Baltimore, Md.) 2016;64 (3):711-713 [PubMed]
  • Robciuc Marius R., Kivelä Riikka, Williams Ian M., de Boer Jan Freark, van Dijk Theo H., Elamaa Harri, Tigistu-Sahle Feven, Molotkov Dmitry, Leppänen Veli-Matti, Käkelä Reijo, Eklund Lauri, Wasserman David H., Groen Albert K., Alitalo Kari VEGFB/VEGFR1-Induced Expansion of Adipose Vasculature Counteracts Obesity and Related Metabolic Complications Cell metabolism 2016;23 (4):712-724 [PubMed]
  • Reijne Aaffien C., Ciapaite Jolita, van Dijk Theo H., Havinga Rick, van der Zee Eddy A., Groen Albert K., Reijngoud Dirk-Jan, Bakker Barbara M., van Dijk Gertjan Whole-Body Vibration Partially Reverses Aging-Induced Increases in Visceral Adiposity and Hepatic Lipid Storage in Mice PLoS ONE 2016;11 (2):e0149419 [PubMed]

2015

  • de Smet Els, Mensink Ronald P., Konings Maurice, Brufau Gemma, Groen Albert K., Havinga Rick, Schonewille Marleen, Kerksiek Anja, Lütjohann Dieter, Plat Jogchum Acute Intake of Plant Stanol Esters Induces Changes in Lipid and Lipoprotein Metabolism-Related Gene Expression in the Liver and Intestines of Mice Lipids 2015;50 (6):529-541 [PubMed]
  • Hijmans Brenda S., Tiemann Christian A., Grefhorst Aldo, Boesjes Marije, van Dijk Theo H., Tietge Uwe J. F., Kuipers Folkert, van Riel Natal A. W., Groen Albert K., Oosterveer Maaike H. A systems biology approach reveals the physiological origin of hepatic steatosis induced by liver X receptor activation FASEB journal 2015;29 (4):1153-1164 [PubMed]
  • Zhang Xiang, Kuivenhoven Jan A., Groen Albert K. Bacterial symbionts, Buchnera, and starvation on wing dimorphism in English grain aphid, Sitobion avenae (F.) (Homoptera: Aphididae) Frontiers in physiology 2015;6:155 [PubMed]
  • Kuivenhoven J. A., Groen A. K. Beyond the genetics of HDL: why is HDL cholesterol inversely related to cardiovascular disease? Handbook of experimental pharmacology 2015;224:285-300 [PubMed]
  • Correia Jorge C., Massart Julie, de Boer Jan Freark, Porsmyr-Palmertz Margareta, Martínez-Redondo Vicente, Agudelo Leandro Z., Sinha Indranil, Meierhofer David, Ribeiro Vera, Björnholm Marie, Sauer Sascha, Dahlman-Wright Karin, Zierath Juleen R., Groen Albert K., Ruas Jorge L. Bioenergetic cues shift FXR splicing towards FXR alpha 2 to modulate hepatic lipolysis and fatty acid metabolism Molecular metabolism 2015;4 (12):891-902 [PubMed]
  • Barrera Francisco, Azócar Lorena, Molina Héctor, Schalper Kurt A., Ocares Marcia, Liberona Jessica, Villarroel Luis, Pimentel Fernando, Pérez-Ayuso Rosa M., Nervi Flavio, Groen Albert K., Miquel Juan F. Effect of cholecystectomy on bile acid synthesis and circulating levels of fibroblast growth factor 19 Annals of hepatology 2015;14 (5):710-721 [PubMed]
  • Kootte Ruud S., Smits Loek P., van der Valk Fleur M., Dasseux Jean-Louis, Keyserling Constance H., Barbaras Ronald, Paolini John F., Santos Raul D., van Dijk Theo H., Dallinga-van Thie Geesje M., Nederveen Aart J., Mulder Willem J. M., Hovingh G. Kees, Kastelein John J. P., Groen Albert K., Stroes Erik S. Effect of open-label infusion of an apoA-I-containing particle (CER-001) on RCT and artery wall thickness in patients with FHA Journal of lipid research 2015;56 (3):703-712 [PubMed]
  • Janssens Sharon, Jonkers Richard A. M., Groen Albert K., Nicolay Klaas, van Loon Luc J. C., Prompers Jeanine J. Effects of acute exercise on lipid content and dietary lipid uptake in liver and skeletal muscle of lean and diabetic rats American journal of physiology. Endocrinology and metabolism 2015;309 (10):E874-E883 [PubMed]
  • Paalvast Yared, Kuivenhoven Jan Albert, Groen Albert K. Evaluating computational models of cholesterol metabolism BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 2015;1851 (10):1360-1376 [PubMed]
  • Out Carolien, Patankar Jay V., Doktorova Marcela, Boesjes Marije, Bos Trijnie, de Boer Sanna, Havinga Rick, Wolters Henk, Boverhof Renze, van Dijk Theo H., Smoczek Anna, Bleich André, Sachdev Vinay, Kratky Dagmar, Kuipers Folkert, Verkade Henkjan J., Groen Albert K. Gut microbiota inhibit Asbt-dependent intestinal bile acid reabsorption via Gata4 Journal of hepatology 2015;63 (3):697-704 [PubMed]
  • Dikkers Arne, de Boer Jan Freark, Groen Albert K., Tietge Uwe J. F. Hepatic ABCG5/G8 overexpression substantially increases biliary cholesterol secretion but does not impact in vivo macrophage-to-feces RCT Atherosclerosis 2015;243 (2):402-406 [PubMed]
  • Kaur Achint, Patankar Jay V., de Haan Willeke, Ruddle Piers, Wijesekara Nadeeja, Groen Albert K., Verchere C. Bruce, Singaraja Roshni R., Hayden Michael R. Loss of Cyp8b1 Improves Glucose Homeostasis by Increasing GLP-1 Diabetes 2015;64 (4):1168-1179 [PubMed]
  • Boesjes Marije Novel insights into FXR actions in liver and intestine 2015. 143p. ISBN 9789036781640. [UvA Dissertations Online] University of Groningen: Department of Pediatrics, Center for Liver, Digestive and Metabolic Diseases. (Supervisors: Groen A. K., Kuipers F.)
  • den Besten Gijs, Gerding Albert, van Dijk Theo H., Ciapaite Jolita, Bleeker Aycha, van Eunen Karen, Havinga Rick, Groen Albert K., Reijngoud Dirk-Jan, Bakker Barbara M. Protection against the Metabolic Syndrome by Guar Gum-Derived Short-Chain Fatty Acids Depends on Peroxisome Proliferator-Activated Receptor. and Glucagon-Like Peptide-1 PLoS ONE 2015;10 (8):e0136364 [PubMed]
  • van Olden Casper, Groen Albert K., Nieuwdorp Max Role of Intestinal Microbiome in Lipid and Glucose Metabolism in Diabetes Mellitus Clinical therapeutics 2015;37 (6):1172-1177 [PubMed]
  • Pruis M. G. M., Gellhaus A., Kühnel E., Lendvai Á, Bloks V. W., Groen A. K., Plösch T. Sex-specific placental differences as a contributor to sex-specific metabolic programming? Acta physiologica (Oxford, England) 2015;215 (3):127-129 [PubMed]
  • den Besten Gijs, Bleeker Aycha, Gerding Albert, van Eunen Karen, Havinga Rick, van Dijk Theo H., Oosterveer Maaike H., Jonker Johan W., Groen Albert K., Reijngoud Dirk-Jan, Bakker Barbara M. Short-Chain Fatty Acids Protect Against High-Fat Diet-Induced Obesity via a PPAR-Dependent Switch From Lipogenesis to Fat Oxidation Diabetes 2015;64 (7):2398-2408 [PubMed]
  • Vaz Frédéric M., Paulusma Coen C., Huidekoper Hidde, de Ru Minke, Lim Cynthia, Koster Janet, Ho-Mok Kam, Bootsma Albert H., Groen Albert K., Schaap Frank G., Oude Elferink Ronald P. J., Waterham Hans R., Wanders Ronald J. A. Sodium taurocholate cotransporting polypeptide (SLC10A1) deficiency: conjugated hypercholanemia without a clear clinical phenotype Hepatology (Baltimore, Md.) 2015;61 (1):260-267 [PubMed]
  • Pruis Genoveva Maurien Mirella Towards the mechanism of early-life programming: Consequences of a maternal western diet 2015. 139p. ISBN 9789462992313. [UvA Dissertations Online] University of Groningen: epartment of Pediatrics, Center for Liver, Digestive, and Metabolic diseases,. (Supervisors: Groen A. K., Verkade H. J.; Co-supervisor: Plösch T.)

2014

  • Sips Fianne L. P., Tiemann Christian A., Oosterveer Maaike H., Groen Albert K., Hilbers Peter A. J., van Riel Natal A. W. A Computational Model for the Analysis of Lipoprotein Distributions in the Mouse: Translating FPLC Profiles to Lipoprotein Metabolism PLoS computational biology 2014;10 (5):e1003579 [PubMed]
  • Mattijssen Frits, Alex Sheril, Swarts Hans J., Groen Albert K., van Schothorst Evert M., Kersten Sander Angptl4 serves as an endogenous inhibitor of intestinal lipid digestion Molecular metabolism 2014;3 (2):135-144 [PubMed]
  • Kuipers Folkert, Bloks Vincent W., Groen Albert K. Beyond intestinal soap-bile acids in metabolic control Nature reviews. Endocrinology 2014;10 (8):488-498 [PubMed]
  • Funke Anouk, Schreurs Marijke, Aparicio-Vergara Marcela, Sheedfar Fareeba, Gruben Nanda, Kloosterhuis Niels J., Shiri-Sverdlov Ronit, Groen Albert K., van de Sluis Bart, Hofker Marten H., Koonen Debby P. Y. Cholesterol-induced hepatic inflammation does not contribute to the development of insulin resistance in male LDL receptor knockout mice Atherosclerosis 2014;232 (2):390-396 [PubMed]
  • Groen Albert K., Bloks Vincent W., Verkade Henkjan, Kuipers Folkert Cross-talk between liver and intestine in control of cholesterol and energy homeostasis Molecular aspects of medicine 2014;37:77-88 [PubMed]
  • Touw C. M. L., Derks T. G. J., Bakker B. M., Groen A. K., Smit G. P. A., Reijngoud D. J. From genome to phenome-Simple inborn errors of metabolism as complex traits BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 2014;1842 (10):2021-2029 [PubMed]
  • Kuipers Folkert, Groen Albert K. FXR: the key to benefits in bariatric surgery? Nature medicine 2014;20 (4):337-338 [PubMed]
  • Toonen Erik J. M., Laskewitz Anke J., van Dijk Theo H., Bleeker Aycha, Grefhorst Aldo, Schouten Annelies E., Bastiaanssen Ellen A. J., Ballak Dov B., Koenders Marije I., van Doorn Cindy, van der Vleuten Monique A. J., van Lierop Marie-Jose C., Groen Albert K., Dokter Wim H. A. Glucose Kinetics in the Collagen-Induced Arthritis Model: An All-in-One Model to Assess Both Efficacy and Metabolic Side Effects of Glucocorticoids PLoS ONE 2014;9 (9):e98684 [PubMed]
  • Out Carolien Gut microbiota and nuclear receptors in bile acid and lipid metabolism: bile acids, more than soaps 2014. 206p. ISBN 9789053359020. [UvA Dissertations Online] University of Groningen: Department of Pediatrics, Center for Liver, Digestive and Metabolic Diseases. (Supervisors: Groen A. K., Verkade H. J.)
  • Boesjes Marije, Bloks Vincent W., Hageman Jurre, Bos Trijnie, van Dijk Theo H., Havinga Rick, Wolters Henk, Jonker Johan W., Kuipers Folkert, Groen Albert K. Hepatic Farnesoid X-Receptor Isoforms alpha 2 and alpha 4 Differentially Modulate Bile Salt and Lipoprotein Metabolism in Mice PLoS ONE 2014;9 (12):e115028 [PubMed]
  • Vrieze Anne, Out Carolien, Fuentes Susana, Jonker Lisanne, Reuling Isaie, Kootte Ruud S., van Nood Els, Holleman Frits, Knaapen Max, Romijn Johannes A., Soeters Maarten R., Blaak Ellen E., Dallinga-Thie Geesje M., Reijnders Dorien, Ackermans Mariette T., Serlie Mireille J., Knop Filip K., Holst Jenst J., van der Ley Claude, Kema Ido P., Zoetendal Erwin G., de Vos Willem M., Hoekstra Joost B. L., Stroes Erik S., Groen Albert K., Nieuwdorp Max Impact of oral vancomycin on gut microbiota, bile acid metabolism, and insulin sensitivity Journal of hepatology 2014;60 (4):824-831 [PubMed]
  • Pruis M. G. M., Lendvai A., Bloks V. W., Zwier M. V., Baller J. F. W., de Bruin A., Groen A. K., Plösch T. Maternal western diet primes non-alcoholic fatty liver disease in adult mouse offspring Acta physiologica (Oxford, England) 2014;210 (1):215-227 [PubMed]
  • Lien Fleur, Berthier Alexandre, Bouchaert Emmanuel, Gheeraert Céline, Alexandre Jeremy, Porez Geoffrey, Prawitt Janne, Dehondt Hélène, Ploton Maheul, Colin Sophie, Lucas Anthony, Patrice Alexandre, Pattou François, Diemer Hélène, van Dorsselaer Alain, Rachez Christophe, Kamilic Jelena, Groen Albert K., Staels Bart, Lefebvre Philippe Metformin interferes with bile acid homeostasis through AMPK-FXR crosstalk Journal of clinical investigation 2014;124 (3):1037-1051 [PubMed]
  • Out Carolien, Dikkers Arne, Laskewitz Anke, Boverhof Renze, van der Ley Claude, Kema Ido P., Wolters Henk, Havinga Rick, Verkade Henkjan J., Kuipers Folkert, Tietge Uwe J. F., Groen Albert K. Prednisolone increases enterohepatic cycling of bile acids by induction of Asbt and promotes reverse cholesterol transport Journal of hepatology 2014;61 (2):351-357 [PubMed]
  • Schonewille Marleen, Brufau Gemma, Shiri-Sverdlov Ronit, Groen Albert K., Plat Jogchum Serum TG-lowering properties of plant sterols and stanols are associated with decreased hepatic VLDL secretion Journal of lipid research 2014;55 (12):2554-2561 [PubMed]
  • den Besten Gijs, Havinga Rick, Bleeker Aycha, Rao Shodhan, Gerding Albert, van Eunen Karen, Groen Albert K., Reijngoud Dirk-Jan, Bakker Barbara M. The Short-Chain Fatty Acid Uptake Fluxes by Mice on a Guar Gum Supplemented Diet Associate with Amelioration of Major Biomarkers of the Metabolic Syndrome PLoS ONE 2014;9 (9):e107392 [PubMed]
  • Hijmans Brenda S., Grefhorst Aldo, Oosterveer Maaike H., Groen Albert K. Zonation of glucose and fatty acid metabolism in the liver: Mechanism and metabolic consequences Biochimie 2014;96:121-129 [PubMed]

2013

  • van Dijk T. H., Laskewitz A. J., Grefhorst A., Boer T. S., Bloks V. W., Kuipers F., Groen A. K., Reijngoud D. J. A novel approach to monitor glucose metabolism using stable isotopically labelled glucose in longitudinal studies in mice Laboratory animals 2013;47 (2):79-88 [PubMed]
  • Groen Albert K., Kuipers Folkert Bile Acid Look-Alike Controls Life Span in C. elegans Cell metabolism 2013;18 (2):151-152 [PubMed]
  • Out Carolien, Kuipers Folkert, Groen Albert K. Bile Acids and Cholestasis Gastroenterology 2013;144 (2):E17-E18 [PubMed]
  • Meissner Maxi, Wolters Henk, de Boer Rudolf A., Havinga Rick, Boverhof Renze, Bloks Vincent W., Kuipers Folkert, Groen Albert K. Bile acid sequestration normalizes plasma cholesterol and reduces atherosclerosis in hypercholesterolemic mice. No additional effect of physical activity Atherosclerosis 2013;228 (1):117-123 [PubMed]
  • van Eunen Karen, Simons Sereh M. J., Gerding Albert, Bleeker Aycha, den Besten Gijs, Touw Catharina M. L., Houten Sander M., Groen Bert K., Krab Klaas, Reijngoud Dirk-Jan, Bakker Barbara M. Biochemical competition makes fatty-acid β-oxidation vulnerable to substrate overload PLoS computational biology 2013;9 (8):e1003186 [PubMed]
  • Sokolović Aleksandar, van Roomen Cindy P. A. A., Ottenhoff Roelof, Scheij Saskia, Hiralall Johan K., Claessen Nike, Aten Jan, Oude Elferink Ronald P. J., Groen Albert K., Sokolović Milka Fasting reduces liver fibrosis in a mouse model for chronic cholangiopathies BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 2013;1832 (10):1482-1491 [PubMed]
  • Lombardo Elisa Glycosphingolipids and atherosclerosis 2013. 223p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Aerts J. M. F. G.; Co-supervisors: Groen A. K., Bietrix F. M. D. F.)
  • den Besten Gijs, Lange Katja, Havinga Rick, van Dijk Theo H., Gerding Albert, van Eunen Karen, Müller Michael, Groen Albert K., Hooiveld Guido J., Bakker Barbara M., Reijngoud Dirk-Jan Gut-derived short-chain fatty acids are vividly assimilated into host carbohydrates and lipids American journal of physiology. Gastrointestinal and liver physiology 2013;305 (12):G900-G910 [PubMed]
  • Houten Sander M., Herrema Hilde, te Brinke Heleen, Denis Simone, Ruiter Jos P. N., van Dijk Theo H., Argmann Carmen A., Ottenhoff Roelof, Müller Michael, Groen Albert K., Kuipers Folkert, Reijngoud Dirk-Jan, Wanders Ronald J. A. Impaired amino acid metabolism contributes to fasting-induced hypoglycemia in fatty acid oxidation defects Human molecular genetics 2013;22 (25):5249-5261 [PubMed]
  • Thedieck Kathrin, Holzwarth Birgit, Prentzell Mirja Tamara, Boehlke Christopher, Kläsener Kathrin, Ruf Stefanie, Sonntag Annika Gwendolin, Maerz Lars, Grellscheid Sushma-Nagaraja, Kremmer Elisabeth, Nitschke Roland, Kuehn E. Wolfgang, Jonker Johan W., Groen Albert K., Reth Michael, Hall Michael N., Baumeister Ralf Inhibition of mTORC1 by Astrin and Stress Granules Prevents Apoptosis in Cancer Cells Cell 2013;154 (4):859-874 [PubMed]
  • Thedieck Kathrin, Holzwarth Birgit, Prentzell Mirja Tamara, Boehlke Christopher, Klaesener Kathrin, Ruf Stefanie, Sonntag Annika Gwendolin, Maerz Lars, Grellscheid Sushma-Nagaraja, Kremmer Elisabeth, Nitschke Roland, Kuehn E. Wolfgang, Jonker Johan W., Groen Albert K., Reth Michael, Hall Michael N., Baumeister Ralf Inhibition of mTORC1 by Astrin and Stress Granules Prevents Apoptosis in Cancer Cells (vol 154, pg 859, 2013) Cell 2013;155 (4):964-966
  • Jakulj L., Besseling J., Stroes E. S. G., Groen A. K. Intestinal cholesterol secretion: future clinical implications Netherlands journal of medicine 2013;71 (9):459-465 [PubMed]
  • Jakulj L. Intestinal cholesterol transport: measuring cholesterol absorption and its reverse 2013. 176p. ISBN 9789082043709. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Groen A. K., Stroes E. S. G.; Co-supervisor: Vissers M. N.)
  • Holleboom Adriaan G., Jakulj Lily, Franssen Remco, Decaris Julie, Vergeer Menno, Koetsveld Joris, Luchoomun Jayraz, Glass Alexander, Hellerstein Marc K., Kastelein John J. P., Hovingh G. Kees, Kuivenhoven Jan Albert, Groen Albert K., Turner Scott M., Stroes Erik S. G. In vivo tissue cholesterol efflux is reduced in carriers of a mutation in APOA1 Journal of lipid research 2013;54 (7):1964-1971 [PubMed]
  • Sondermeijer Brigitte M., Battjes Suzanne, van Dijk Theo H., Ackermans Mariëtte T., Serlie Mireille J., Nieuwdorp Max, Groen Albert K., Dallinga-Thie Geesje M., Stroes Erik S. G. Lactate increases hepatic secretion of VLDL-triglycerides in humans Atherosclerosis 2013;228 (2):443-450 [PubMed]
  • van der Wulp Mariëtte Y. M., Derrien Muriel, Stellaard Frans, Wolters Henk, Kleerebezem Michiel, Dekker Jan, Rings Edmond H. H. M., Groen Albert K., Verkade Henkjan J. Laxative treatment with polyethylene glycol decreases microbial primary bile salt dehydroxylation and lipid metabolism in the intestine of rats American journal of physiology. Gastrointestinal and liver physiology 2013;305 (7):G474-G482 [PubMed]
  • Mischke Mona, Pruis Maurien G. M., Boekschoten Mark V., Groen Albert K., Fitri Aditia R., van de Heijning Bert J. M., Verkade Henkjan J., Müller Michael, Plösch Torsten, Steegenga Wilma T. Maternal Western-Style High Fat Diet Induces Sex-Specific Physiological and Molecular Changes in Two-Week-Old Mouse Offspring PLoS ONE 2013;8 (11):e78623 [PubMed]
  • Tiemann Christian A., Vanlier Joep, Oosterveer Maaike H., Groen Albert K., Hilbers Peter A. J., van Riel Natal A. W. Parameter Trajectory Analysis to Identify Treatment Effects of Pharmacological Interventions PLoS computational biology 2013;9 (8):e1003166 [PubMed]
  • Jakulj Lily, Mohammed Hussein, van Dijk Theo H., Boer Theo, Turner Scott, Groen Albert K., Vissers Maud N., Stroes Erik S. G. Plasma plant sterols serve as poor markers of cholesterol absorption in man Journal of lipid research 2013;54 (4):1144-1150 [PubMed]
  • van der Wulp Mariëtte Y. M., Verkade Henkjan J., Groen Albert K. Regulation of cholesterol homeostasis Molecular and cellular endocrinology 2013;368 (1-2):1-16 [PubMed]
  • Tietge Uwe J. F., Groen Albert K. Role the TICE?: Advancing the Concept of Transintestinal Cholesterol Excretion Arteriosclerosis, thrombosis, and vascular biology 2013;33 (7):1452-1453 [PubMed]
  • Dikkers Arne, Freak de Boer Jan, Annema Wijtske, Groen Albert K., Tietge Uwe J. F. Scavenger Receptor BI and ABCG5/G8 Differentially Impact Biliary Sterol Secretion and Reverse Cholesterol Transport in Mice Hepatology (Baltimore, Md.) 2013;58 (1):293-303 [PubMed]
  • den Besten Gijs, van Eunen Karen, Groen Albert K., Venema Koen, Reijngoud Dirk-Jan, Bakker Barbara M. The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism Journal of lipid research 2013;54 (9):2325-2340 [PubMed]

2012

  • Soler Jean K., Okkes Inge, Oskam Sibo, van Boven Kees, Zivotic Predrag, Jevtic Milan, Dobbs Frank, Lamberts Henk, van Boven C., Dijksterhuis P. H., Groen A., de Haan J., Honselaar-de Groot A. M., Janssen D., Polman T. A. L., Polderman G. O., Stolp K. E. I., Valken N., Veltman M. T. M., Woerdeman M., Calleja Francis Paul, Sammut Carmen, Sammut Mario R., Sammut Daniel, Sammut David, Bonnici Jason, Buhagiar John, Baldacchino Andrew An international comparative family medicine study of the Transition Project data from the Netherlands, Malta and Serbia. Is family medicine an international discipline? Comparing diagnostic odds ratios across populations Family practice 2012;29 (3):299-314 [PubMed]
  • Soler Jean K., Okkes Inge, Oskam Sibo, van Boven Kees, Zivotic Predrag, Jevtic Milan, Dobbs Frank, Lamberts Henk, van Boven C., Dijksterhuis P. H., Groen A., de Haan J., Honselaar-de Groot A. M., Janssen D., Polman T. A. L., Polderman G. O., Stolp K. E. I., Valken N., Veltman M. T. M., Woerdeman M., Calleja Francis Paul, Sammut Carmen, Sammut Mario R., Sammut Daniel, Sammut David, Bonnici Jason, Buhagiar John, Baldacchino Andrew An international comparative family medicine study of the Transition Project data from the Netherlands, Malta and Serbia. Is family medicine an international discipline? Comparing incidence and prevalence rates of reasons for encounter and diagnostic titles of episodes of care across populations Family practice 2012;29 (3):283-298 [PubMed]
  • Soler Jean K., Okkes Inge, Oskam Sibo, van Boven Kees, Zivotic Predrag, Jevtic Milan, Dobbs Frank, Lamberts Henk, van Boven C., Dijksterhuis P. H., Groen A., de Haan J., Honselaar-de Groot A. M., Janssen D., Polman T. A. L., Polderman G. O., Stolp K. E. I., Valken N., Veltman M. T. M., Woerdeman M., Calleja Francis Paul, Sammut Carmen, Sammut Mario R., Sammut Daniel, Sammut David, Bonnici Jason, Buhagiar John, Baldacchino Andrew An international comparative family medicine study of the Transition Project data from the Netherlands, Malta, Japan and Serbia. An analysis of diagnostic odds ratios aggregated across age bands, years of observation and individual practices Family practice 2012;29 (3):315-331 [PubMed]
  • Out Carolien, Groen Albert K., Brufau Gemma Bile acid sequestrants: more than simple resins Current opinion in lipidology 2012;23 (1):43-55 [PubMed]
  • Laskewitz Anke J., van Dijk Theo H., Grefhorst Aldo, van Lierop Marie-José, Schreurs Marijke, Bloks Vincent W., Reijngoud Dirk-Jan, Dokter Wim H., Kuipers Folkert, Groen Albert K. Chronic Prednisolone Treatment Aggravates Hyperglycemia in Mice Fed a High-Fat Diet but Does Not Worsen Dietary Fat-Induced Insulin Resistance Endocrinology 2012;153 (8):3713-3723 [PubMed]
  • Lombardo Elisa, van Roomen Cindy P. A. A., van Puijvelde Gijs H., Ottenhoff Roelof, van Eijk Marco, Aten Jan, Kuiper Johan, Overkleeft Herman S., Groen Albert K., Verhoeven Arthur J., Aerts Johannes M. F. G., Bietrix Florence Correction of Liver Steatosis by a Hydrophobic Iminosugar Modulating Glycosphingolipids Metabolism PLoS ONE 2012;7 (10):e38520-(10 p.) [PubMed]
  • Hoekstra Menno, van der Sluis Ronald J., Li Zhaosha, Oosterveer Maaike H., Groen Albert K., van Berkel Theo J. C. FXR agonist GW4064 increases plasma glucocorticoid levels in C57BL/6 mice Molecular and cellular endocrinology 2012;362 (1-2):69-75 [PubMed]
  • Laskewitz Anke J. Getting grip on glucocorticoid-induced metabolic derangements 2012. 221p. ISBN 9789036753517. [UvA Dissertations Online] University of Groningen: Department of Pediatrics. (Supervisors: Kuipers F., Groen A. K.)
  • van der Wulp Mariëtte Y. M., Cuperus Frans J. C., Stellaard Frans, van Dijk Theo H., Dekker Jan, Rings Edmond H. H. M., Groen Albert K., Verkade Henkjan J. Laxative Treatment With Polyethylene Glycol Does Not Affect Lipid Absorption in Rats Journal of pediatric gastroenterology and nutrition 2012;55 (4):457-462 [PubMed]
  • Oosterveer Maaike H., Mataki Chikage, Yamamoto Hiroyasu, Harach Taoufiq, Moullan Norman, van Dijk Theo H., Ayuso Eduard, Bosch Fatima, Postic Catherine, Groen Albert K., Auwerx Johan, Schoonjans Kristina LRH-1-dependent glucose sensing determines intermediary metabolism in liver Journal of clinical investigation 2012;122 (8):2817-2826 [PubMed]
  • Grefhorst Aldo, Oosterveer Maaike H., Brufau Gemma, Boesjes Marije, Kuipers Folkert, Groen Albert K. Pharmacological LXR activation reduces presence of SR-B1 in liver membranes contributing to LXR-mediated induction of HDL-cholesterol Atherosclerosis 2012;222 (2):382-389 [PubMed]
  • Kootte R. S., Vrieze A., Holleman F., Dallinga-Thie G. M., Zoetendal E. G., de Vos W. M., Groen A. K., Hoekstra J. B. L., Stroes E. S., Nieuwdorp M. The therapeutic potential of manipulating gut microbiota in obesity and type 2 diabetes mellitus Diabetes, obesity & metabolism 2012;14 (2):112-120 [PubMed]
  • van der Wulp Mariëtte Y. M. Towards novel strategies to improve lipid homeostasis - targeting the intestine 2012. 133p. ISBN 9789036757973. [UvA Dissertations Online] University of Groningen: Department of Pediatrics, Beatrix Children's Hospital, Center for Liver, Digestive and Metabolic Diseases. (Supervisors: Verkade H. J., Groen A. K., Rings E. H. H. M.)
  • Vrieze Anne, van Nood Els, Holleman Frits, Salojärvi Jarkko, Kootte Ruud S., Bartelsman Joep F. W. M., Dallinga-Thie Geesje M., Ackermans Mariette T., Serlie Mireille J., Oozeer Raish, Derrien Muriel, Druesne Anne, van Hylckama Vlieg Johan E. T., Bloks Vincent W., Groen Albert K., Heilig Hans G. H. J., Zoetendal Erwin G., Stroes Erik S., de Vos Willem M., Hoekstra Joost B. L., Nieuwdorp Max Transfer of Intestinal Microbiota From Lean Donors Increases Insulin Sensitivity in Individuals With Metabolic Syndrome Gastroenterology 2012;143 (4):913-+ [PubMed]
  • Vrins Carlos L. J., Ottenhoff Roelof, van den Oever Karin, de Waart Dirk R., Kruyt J. Kar, Zhao Ying, van Berkel Theo J. C., Havekes Louis M., Aerts Johannes M., van Eck Miranda, Rensen Patrick C. N., Groen Albert K. Trans-intestinal cholesterol efflux is not mediated through high density lipoprotein Journal of lipid research 2012;53 (10):2017-2023 [PubMed]
  • Langeveld Mirjam, van den Berg Sjoerd A. A., Bijl Nora, Bijland Silvia, van Roomen Cindy P., Houben-Weerts Judith H., Ottenhoff Roelof, Houten Sander M., van Dijk Ko Willems, Romijn Johannes A., Groen Albert K., Aerts Johannes M., Voshol Peter J. Treatment of genetically obese mice with the iminosugar N-(5-adamantane-1-yl-methoxy-pentyl)-deoxynojirimycin reduces body weight by decreasing food intake and increasing fat oxidation Metabolism: clinical and experimental 2012;61 (1):99-107 [PubMed]

2011

  • Brufau Gemma, Kuipers Folkert, Lin Yuguang, Trautwein Elke A., Groen Albert K. A Reappraisal of the Mechanism by Which Plant Sterols Promote Neutral Sterol Loss in Mice PLoS ONE 2011;6 (6):e21576 [PubMed]
  • Meissner Maxi, Herrema Hilde, van Dijk Theo H., Gerding Albert, Havinga Rick, Boer Theo, Müller Michael, Reijngoud Dirk-Jan, Groen Albert K., Kuipers Folkert Bile Acid Sequestration Reduces Plasma Glucose Levels in db/db Mice by Increasing Its Metabolic Clearance Rate PLoS ONE 2011;6 (11):e24564 [PubMed]
  • Brufau Gemma, Groen Albert K. Characterization of Whole Body Cholesterol Fluxes in the Mouse Current protocols in mouse biology 2011;1 (4):413-427 [PubMed]
  • de Vries Rindert, Groen Albert K., Dullaart Robin P. F. Cholesterol Efflux Capacity and Atherosclerosis New England journal of medicine 2011;364 (15):1473-1474 [PubMed]
  • Aerts Johannes M., Boot Rolf G., van Eijk Marco, Groener Johanna, Bijl Nora, Lombardo Elisa, Bietrix Florence M., Dekker Nick, Groen Albert K., Ottenhoff Roelof, van Roomen Cindy, Aten Jan, Serlie Mireille, Langeveld Mirjam, Wennekes Tom, Overkleeft Hermen S. Glycosphingolipids and insulin resistance Advances in experimental medicine and biology 2011;721:99-119 [PubMed]
  • Zhao Ying, Pennings Marieke, Vrins Carlos L. J., Calpe-Berdiel Laura, Hoekstra Menno, Kruijt J. Kar, Ottenhoff Roelof, Hildebrand Reeni B., van der Sluis Ronald, Jessup Wendy, Le Goff Wilfried, Chapman M. John, Huby Thierry, Groen Albert K., van Berkel Theo J. C., van Eck Miranda Hypocholesterolemia, foam cell accumulation, but no atherosclerosis in mice lacking ABC-transporter A1 and scavenger receptor BI Atherosclerosis 2011;218 (2):314-322 [PubMed]
  • Out Carolien, Hageman Jurre, Bloks Vincent W., Gerrits Han, Sollewijn Gelpke Maarten D., Bos Trijnie, Havinga Rick, Smit Martin J., Kuipers Folkert, Groen Albert K. Liver Receptor Homolog-1 Is Critical for Adequate Up-regulation of Cyp7a1 Gene Transcription and Bile Salt Synthesis During Bile Salt Sequestration Hepatology (Baltimore, Md.) 2011;53 (6):2075-2085 [PubMed]
  • Brufau Gemma, Groen Albert K., Kuipers Folkert Reverse Cholesterol Transport Revisited Contribution of Biliary Versus Intestinal Cholesterol Excretion Arteriosclerosis, thrombosis, and vascular biology 2011;31 (8):1726-1733 [PubMed]
  • Brands Myrte, Hoeks Joris, Sauerwein Hans P., Ackermans Mariette T., Ouwens Margriet, Lammers Nicolette M., van der Plas Mart N., Schrauwen Patrick, Groen Albert K., Serlie Mireille J. Short-term increase of plasma free fatty acids does not interfere with intrinsic mitochondrial function in healthy young men Metabolism: clinical and experimental 2011;60 (10):1398-1405 [PubMed]
  • Meissner Maxi, Lombardo Elisa, Havinga Rick, Tietge Uwe J. F., Kuipers Folkert, Groen Albert K. Voluntary wheel running increases bile acid as well as cholesterol excretion and decreases atherosclerosis in hypercholesterolemic mice Atherosclerosis 2011;218 (2):323-329 [PubMed]

2010

  • Hageman Jurre, Herrema Hilde, Groen Albert K., Kuipers Folkert A Role of the Bile Salt Receptor FXR in Atherosclerosis Arteriosclerosis, thrombosis, and vascular biology 2010;30 (8):1519-1528 [PubMed]
  • Jakulj Lily, Vissers Maud N., Groen Albert K., Hutten Barbara A., Lutjohann Dieter, Veltri Enrico P., Kastelein John J. P. Baseline cholesterol absorption and the response to ezetimibe/simvastatin therapy: a post-hoc analysis of the ENHANCE trial Journal of lipid research 2010;51 (4):755-762 [PubMed]
  • Herrema Hilde, Meissner Maxi, van Dijk Theo H., Brufau Gemma, Boverhof Renze, Oosterveer Maaike H., Reijngoud Dirk-Jan, Müller Michael, Stellaard Frans, Groen Albert K., Kuipers Folkert Bile Salt Sequestration Induces Hepatic De Novo Lipogenesis Through Farnesoid X Receptor- and Liver X Receptor alpha-Controlled Metabolic Pathways in Mice Hepatology (Baltimore, Md.) 2010;51 (3):806-816 [PubMed]
  • Grefhorst Aldo, Schreurs Marijke, Oosterveer Maaike H., Cortés Victor A., Havinga Rick, Herling Andreas W., Reijngoud Dirk-Jan, Groen Albert K., Kuipers Folkert Carbohydrate-response-element-binding protein (ChREBP) and not the liver X receptor alpha (LXR alpha) mediates elevated hepatic lipogenic gene expression in a mouse model of glycogen storage disease type 1 Biochemical journal 2010;432 (2):249-254 [PubMed]
  • Laskewitz Anke J., van Dijk Theo H., Bloks Vincent W., Reijngoud Dirk-Jan, van Lierop Marie-José, Dokter Wim H., Kuipers Folkert, Groen Albert K., Grefhorst Aldo Chronic Prednisolone Treatment Reduces Hepatic Insulin Sensitivity while Perturbing the Fed-to-Fasting Transition in Mice Endocrinology 2010;151 (5):2171-2178 [PubMed]
  • van Dijk Taeke H. Computational analysis of carbohydrate metabolism: stable isotop techniques in small laboratory animals 2010. 270p. ISBN 9789036743495. [UvA Dissertations Online] University of Groningen: Faculty of Medical Sciences. (Supervisors: Kuipers F., Groen A. K.; Co-supervisor: Reijngoud D.-J.)
  • Wennekes Tom, Meijer Alfred J., Groen Albert K., Boot Rolf G., Groener Johanna E., van Eijk Marco, Ottenhoff Roelof, Bijl Nora, Ghauharali Karen, Song Hang, O'Shea Tom J., Liu Hanlan, Yew Nelson, Copeland Diane, van den Berg Richard J., van der Marel Gijsbert A., Overkleeft Herman S., Aerts Johannes M. Dual-Action Lipophilic Iminosugar Improves Glycemic Control in Obese Rodents by Reduction of Visceral Glycosphingolipids and Buffering of Carbohydrate Assimilation Journal of medicinal chemistry 2010;53 (2):689-698 [PubMed]
  • Zhao Ying, Pennings Marieke, Hildebrand Reeni B., Ye Dan, Calpe-Berdiel Laura, Out Ruud, Kjerrulf Martin, Hurt-Camejo Eva, Groen Albert K., Hoekstra Menno, Jessup Wendy, Chimini Giovanna, van Berkel Theo J. C., van Eck Miranda Enhanced Foam Cell Formation, Atherosclerotic Lesion Development, and Inflammation by Combined Deletion of ABCA1 and SR-BI in Bone Marrow-Derived Cells in LDL Receptor Knockout Mice on Western-Type Diet Circulation research 2010;107 (12):E20-+ [PubMed]
  • Meissner Maxi, Havinga Rick, Boverhof Renze, Kema Ido, Groen Albert K., Kuipers Folkert Exercise Enhances Whole-Body Cholesterol Turnover in Mice Medicine and science in sports and exercise 2010;42 (8):1460-1468 [PubMed]
  • Jakulj Lily, Vissers Maud N., van Roomen Cindy P., van der Veen Jelske N., Vrins Carlos L. J., Kunne Cindy, Stellaard Frans, Kastelein John J. P., Groen Albert K. Ezetimibe stimulates faecal neutral sterol excretion depending on abcg8 function in mice FEBS letters 2010;584 (16):3625-3628 [PubMed]
  • Aerts J. M., Boot R. G., van Eijk M., Groener J., Bijl N., Lombardo E., Bietrix F. M., Dekker N. [=Nick], Groen A. K., Ottenhoff R., van Roomen C., Aten J., Serlie M., Langeveld M., Wennekes T., Overkleeft H. S. Glycosphingolipids and insulin resistancein: A. Cowart, editors. Sphingolipids and Metabolic Disease. S.l.: Landes Bioscience and Springer Science; 2010. p. 20-41, ISBN 9781461406501
  • Bietrix Florence, Lombardo Elisa, van Roomen Cindy P. A. A., Ottenhoff Roelof, Vos Mariska, Rensen Patrick C. N., Verhoeven Arthur J., Aerts Johannes M., Groen Albert K. Inhibition of Glycosphingolipid Synthesis Induces a Profound Reduction of Plasma Cholesterol and Inhibits Atherosclerosis Development in APOE*3 Leiden and Low-Density Lipoprotein Receptor-/- Mice Arteriosclerosis, thrombosis, and vascular biology 2010;30 (5):931-937 [PubMed]
  • Meissner Maxi Interventions in the metabolic syndrome: bile acid sequestration and exercise 2010. 207p. ISBN 9789036746021. [UvA Dissertations Online] University of Groningen: Department of Pediatrics, Center for Liver, Digestive and Metabolic Diseases. (Supervisors: Kuipers F., Groen A. K.)
  • Petruzzelli Mirco Role of phospholipids in the pathophysiology of the gut-liver axis 2010. 213p. [UvA Dissertations Online] University Utrecht: -. (Supervisor: Siersema P. D.; Co-supervisors: Groen A. K., Portincasa P., van Erpecum K. J., Moschetta A.)
  • Oosterveer Maaike H., Grefhorst Aldo, Groen Albert K., Kuipers Folkert The liver X receptor: Control of cellular lipid homeostasis and beyond Implications for drug design Progress in lipid research 2010;49 (4):343-352 [PubMed]
  • van der Velde Astrid E., Brufau Gemma, Groen Albert K. Transintestinal cholesterol efflux Current opinion in lipidology 2010;21 (3):167-171 [PubMed]
  • Sokolović Milka, Sokolović Aleksandar, van Roomen Cindy P. A. A., Gruber Anna, Ottenhoff Roelof, Scheij Saskia, Hakvoort Theodorus B. M., Lamers Wouter H., Groen Albert K. Unexpected effects of fasting on murine lipid homeostasis - Transcriptomic and lipid profiling Journal of hepatology 2010;52 (5):737-744 [PubMed]

2009

  • van der Veen Jelske N., van Dijk Theo H., Vrins Carlos L. J., van Meer Hester, Havinga Rick, Bijsterveld Klaas, Tietge Uwe J. F., Groen Albert K., Kuipers Folkert Activation of the Liver X Receptor Stimulates Trans-intestinal Excretion of Plasma Cholesterol Journal of biological chemistry 2009;284 (29):19211-19219 [PubMed]
  • Plomgaard P., Dullaart R. P. F., de Vries R., Groen A. K., Dahlbäck B., Nielsen L. B. Apolipoprotein M predicts pre-beta-HDL formation: studies in type 2 diabetic and nondiabetic subjects Journal of internal medicine 2009;266 (3):258-267 [PubMed]
  • Bijl N., van der Velde A. E., Groen A. K. Bile salts and their role in cholesterol homeostasisin: C. Ehnholm, editors. Cellular Lipid Metabolism. S.l.: Springer Verlag; 2009. p. 107-130, ISBN 9783642002991
  • Oosterveer Maaike H., Grefhorst Aldo, van Dijk Theo H., Havinga Rick, Staels Bart, Kuipers Folkert, Groen Albert K., Reijngoud Dirk-Jan Fenofibrate Simultaneously Induces Hepatic Fatty Acid Oxidation, Synthesis, and Elongation in Mice Journal of biological chemistry 2009;284 (49):34036-34044 [PubMed]
  • Oosterveer Maaike H., van Dijk Theo H., Tietge Uwe J. F., Boer Theo, Havinga Rick, Stellaard Frans, Groen Albert K., Kuipers Folkert, Reijngoud Dirk-Jan High Fat Feeding Induces Hepatic Fatty Acid Elongation in Mice PLoS ONE 2009;4 (6):e6066 [PubMed]
  • Petruzzelli Michele, Groen Albert K., van Erpecum Karel J., Vrins Carlos, van der Velde Astrid E., Portincasa Piero, Palasciano Giuseppe, van Berge Henegouwen Gerard P., Sasso Giuseppe Lo, Morgano Annalisa, Moschetta Antonio Micellar lipid composition profoundly affects LXR-dependent cholesterol transport across CaCo2 cells FEBS letters 2009;583 (8):1274-1280 [PubMed]
  • Bijl Nora, Sokolović Milka, Vrins Carlos, Langeveld Mirjam, Moerland Perry D., Ottenhoff Roelof, van Roomen Cindy P. A. A., Claessen Nike, Boot Rolf G., Aten Jan, Groen Albert K., Aerts Johannes M. F. G., van Eijk Marco Modulation of Glycosphingolipid Metabolism Significantly Improves Hepatic Insulin Sensitivity and Reverses Hepatic Steatosis in Mice Hepatology (Baltimore, Md.) 2009;50 (5):1431-1441 [PubMed]
  • van der Velde Astrid E. Novel insights in cholesterol excretion 2009. 151p. ISBN 9789064643248. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Oude Elferink R. P. J., Groen A. K.)
  • Vrins Carlos L. J., van der Velde Astrid E., van den Oever Karin, Levels Johannes H. M., Huet Stephane, Oude Elferink Ronald P. J., Kuipers Folkert, Groen Albert K. Peroxisome proliferator-activated receptor delta activation leads to increased transintestinal cholesterol efflux Journal of lipid research 2009;50 (10):2046-2054 [PubMed]
  • Harchaoui Karim El, Franssen Remco, Hovingh G. Kees, Bisoendial Radjesh J., Stellaard Frans, Kuipers Folkert, Kastelein John J. P., Kuivenhoven Jan Albert, Stroes Erik S. G., Groen Albert K. Reduced fecal sterol excretion in subjects with familial hypoalphalipoproteinemia Atherosclerosis 2009;207 (2):614-616 [PubMed]
  • van Eijk Marco, Aten Jan, Bijl Nora, Ottenhoff Roelof, van Roomen Cindy P. A. A., Dubbelhuis Peter F., Seeman Ingar, Ghauharali-van der Vlugt Karen, Overkleeft Hermen S., Arbeeny Cynthia, Groen Albert K., Aerts Johannes M. F. G. Reducing Glycosphingolipid Content in Adipose Tissue of Obese Mice Restores Insulin Sensitivity, Adipogenesis and Reduces Inflammation PLoS ONE 2009;4 (3):e4723 [PubMed]
  • Bijl Nora, van Roomen Cindy P. A. A., Triantis Vassilis, Sokolovic Milka, Ottenhoff Roelof, Scheij Saskia, van Eijk Marco, Boot Rolf G., Aerts Johannes M., Groen Albert K. Reduction of Glycosphingolipid Biosynthesis Stimulates Biliary Lipid Secretion In Mice Hepatology (Baltimore, Md.) 2009;49 (2):637-645 [PubMed]
  • Bijl Nora The role of glycosphingolipids in insulin signaling and lipid metabolism 2009. 199p. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Aerts J. M. F. G., Groen A. K.; Co-supervisor: Boot R. G.)

2008

  • Gerritsen Gery, van der Hoogt Caroline C., Schaap Frank G., Voshol Peter J., Kypreos Kyriakos E., Maeda Nobuyo, Groen Albert K., Havekes Louis M., Rensen Patrick C. N., van Dijk Ko Willems ApoE2-associated hypertriglyceridemia is ameliorated by increased levels of apoA-V but unaffected by apoC-III deficiency Journal of lipid research 2008;49 (5):1048-1055 [PubMed]
  • Kuipers Folkert, Groen Albert K. Chipping away at gallstones Nature medicine 2008;14 (7):715-716 [PubMed]
  • Dullaart Robin P. F., Groen Albert K., Dallinga-Thie Geesje M., de Vries Rindert, Sluiter Wim J., van Tol Arie Fibroblast cholesterol efflux to plasma from metabolic syndrome subjects is not defective despite low high-density lipoprotein cholesterol European journal of endocrinology / European Federation of Endocrine Societies 2008;158 (1):53-60 [PubMed]
  • de Vries R., Groen A. K., Perton F. G., Dallinga-Thie G. M., van Wijland M. J. A., Dikkeschei L. D., Wolffenbuttel B. H. R., van Tol A., Dullaart R. P. F. Increased cholesterol efflux from cultured fibroblasts to plasma from hypertriglyceridemic type 2 diabetic patients: roles of pre beta-HDL, phospholipid transfer protein and cholesterol esterification Atherosclerosis 2008;196 (2):733-741 [PubMed]
  • Pols Thijs W. H., Ottenhoff Roelof, Vos Mariska, Levels Johannes H. M., Quax Paul H. A., Meijers Joost C. M., Pannekoek Hans, Groen Albert K., de Vries Carlie J. M. Nur77 modulates hepatic lipid metabolism through suppression of SREBP1c activity Biochemical and biophysical research communications 2008;366 (4):910-916 [PubMed]
  • van der Velde Astrid E., Vrins Carlos L. J., van den Oever Karin, Seemann Ingar, Oude Elferink Ronald P. J., van Eck Miranda, Kuipers Folkert, Groen Albert K. Regulation of direct transintestinal cholesterol excretion in mice American journal of physiology. Gastrointestinal and liver physiology 2008;295 (1):G203-G208 [PubMed]
  • Borggreve S. E., de Vries R., Dallinga-Thie G. M., Wolffenbuttel B. H. R., Groen A. K., van Tol A., Dullaart R. P. F. The ability of plasma to stimulate fibroblast cholesterol efflux is associated with the -629C-->A cholesteryl ester transfer protein promoter polymorphism: role of lecithin: cholesterol acyltransferase activity BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 2008;1781 (1-2):10-15 [PubMed]
  • Bijl Nora, Scheij Saskia, Houten Sander, Boot Rolf G., Groen Albert K., Aerts Johannes M. F. G. The glucosylceramide synthase inhibitor N-(5-adamantane-1-yl-methoxy-pentyl)-deoxynojirimycin induces sterol regulatory element-binding protein-regulated gene expression and cholesterol synthesis in HepG2 cells Journal of pharmacology and experimental therapeutics 2008;326 (3):849-855 [PubMed]

2007

  • Pennings Marieke, Hildebrand Reeni B., Ye Dan, Kunne Cindy, van Berkel Theo J. C., Groen Albert K., van Eck Miranda Bone marrow-derived multidrug resistance protein ABCB4 protects against atherosclerotic lesion development in LDL receptor knockout mice Cardiovascular research 2007;76 (1):175-183 [PubMed]
  • van der Veen Jelske N., Havinga Rick, Bloks Vincent W., Groen Albert K., Kuipers Folkert Cholesterol feeding strongly reduces hepatic VLDL-triglyceride production in mice lacking the liver X receptor alpha Journal of lipid research 2007;48 (2):337-347 [PubMed]
  • van der Velde Astrid E., Vrins Carlos L. J., van den Oever Karin, Kunne Cindy, Elferink Ronald P. J. Oude, Kljipers Folkert, Groen Albert K. Direct intestinal cholesterol secretion contributes significantly to total fecal neutral sterol excretion in mice Gastroenterology 2007;133 (3):967-975 [PubMed]
  • Ferreira Valérie, van Dijk Ko Willems, Groen Albert K., Vos Rogier M., van der Kaa Jos, Gijbels Marion J. J., Havekes Louis M., Pannekoek Hans Macrophage-specific inhibition of NF-kappaB activation reduces foam-cell formation Atherosclerosis 2007;192 (2):283-290 [PubMed]
  • van der Veen Jelske N. Nuclear receptors in control of cholesterol transport 2007. 159p. ISBN 9789036731645. [UvA Dissertations Online] University of Groningen: Institute for Drug Exploration (GUIDE) e.a.. (Supervisor: Kuipers F.; Co-supervisor: Groen A. K.)
  • van Erpecum Karel J., Petruzzelli Michele, Groen Albert K., Moschetta Antonio Relevance of interactions between sphingomyelin and cholesterol in biliary and intestinal tract EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY 2007;109 (10):982-986
  • Attie Alan D., Flowers Matthew T., Flowers Jessica B., Groen Albert K., Kuipers Folkert, Ntambi James M. Stearoyl-CoA desaturase deficiency, hypercholesterolaemia, cholestasis and diabetes Novartis Foundation symposium 2007;286:47-53; discussion 54-7, 162-3, 196-203 [PubMed]
  • Attie Alan D., Flowers Matthew T., Flowers Jessica B., Groen Albert K., Kuipers Folkert, Ntambi James M. Stearoyl-CoA desaturase deficiency, hypercholesterolemia, cholestasis, and diabetes Nutrition reviews 2007;65 (6 Part 2):S35-S38 [PubMed]
  • Vrins Carlos, Vink Edwin, Vandenberghe Kristin E., Frijters Raoul, Seppen Jurgen, Groen Albert K. The sterol transporting heterodimer ABCG5/ABCG8 requires bile salts to mediate cholesterol efflux FEBS letters 2007;581 (24):4616-4620 [PubMed]

2006

  • Abildayeva Karlygash, Jansen Paula J., Hirsch-Reinshagen Veronica, Bloks Vincent W., Bakker Arjen H. F., Ramaekers Frans C. S., de Vente Jan, Groen Albert K., Wellington Cheryl L., Kuipers Folkert, Mulder Monique 24(S)-hydroxycholesterol participates in a liver X receptor-controlled pathway in astrocytes that regulates apolipoprotein E-mediated cholesterol efflux Journal of biological chemistry 2006;281 (18):12799-12808 [PubMed]
  • Goldiner Ilana, van der Velde Astrid E., Vandenberghe Kristin E., van Wijland Michel A., Halpern Zamir, Gilat Tuvia, Konikoff Fred M., Veldman Robert Jan, Groen Albert K. ABCA1-dependent but apoA-I-independent cholesterol efflux mediated by fatty acid-bile acid conjugates (FABACs) Biochemical journal 2006;396 (3):529-536 [PubMed]
  • Bietrix Florence, Yan Daoguang, Nauze Michel, Rolland Corinne, Bertrand-Michel Justine, Coméra Christine, Schaak Stephane, Barbaras Ronald, Groen Albert K., Perret Bertrand, Tercé François, Collet Xavier Accelerated lipid absorption in mice overexpressing intestinal SR-BI Journal of biological chemistry 2006;281 (11):7214-7219 [PubMed]
  • Vaessen Stefan F. C., Schaap Frank G., Kuivenhoven Jan-Albert, Groen Albert K., Hutten Barbara A., Boekholdt S. Matthijs, Hattori Hiroaki, Sandhu Manjinder S., Bingham Sheila A., Luben Robert, Palmen Jutta A., Wareham Nicholas J., Humphries Steve E., Kastelein John J. P., Talmud Philippa J., Khaw Kay-Tee Apolipoprotein A-V, triglycerides and risk of coronary artery disease: the prospective Epic-Norfolk Population Study Journal of lipid research 2006;47 (9):2064-2070 [PubMed]
  • Vogt Liffert, Laverman Gozewijn D., van Tol Arie, Groen Albert K., Navis Gerjan, Dullaart Robin P. F. Cellular cholesterol efflux to plasma from proteinuric patients is elevated and remains unaffected by antiproteinuric treatment Nephrology, dialysis, transplantation 2006;21 (1):101-106 [PubMed]
  • Flowers Matthew T., Groen Albert K., Oler Angie Tebon, Keller Mark P., Choi YounJeong, Schueler Kathryn L., Richards Oliver C., Lan Hong, Miyazaki Makoto, Kuipers Folkert, Kendziorski Christina M., Ntambi James M., Attie Alan D. Cholestasis and hypercholesterolemia in SCD1-deficient mice fed a low-fat, high-carbohydrate diet Journal of lipid research 2006;47 (12):2668-2680 [PubMed]
  • Jansen Paula J., Lütjohann Dieter, Abildayeva Karlygash, Vanmierlo Tim, Plösch Torsten, Plat Jogchum, von Bergmann Klaus, Groen Albert K., Ramaekers Frans C. S., Kuipers Folkert, Mulder Monique Dietary plant sterols accumulate in the brain BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS 2006;1761 (4):445-453 [PubMed]
  • Kruit Janine-K., Groen Albert K., van Berkel Theo J., Kuipers Folkert Emerging roles of the intestine in control of cholesterol metabolism World journal of gastroenterology 2006;12 (40):6429-6439 [PubMed]
  • Kruit Janine K. Emerging roles of the intestine in reverse cholestorol transport 2006. 151p. ISBN 9789036726559. [UvA Dissertations Online] University of Groningen: Research Institute for Neurosciences and Healthy Ageing (BCN-BRAIN). (Supervisor: Kuipers F.; Co-supervisor: Groen A. K.)
  • Schaap Frank G., Nierman Melchior C., Berbée Jimmy F. P., Hattori Hiroaki, Talmud Philippa J., Vaessen Stefan F. C., Rensen Patrick C. N., Chamuleau Robert A. F. M., Kuivenhoven Jan Albert, Groen Albert K. Evidence for a complex relationship between apoA-V and apoC-III in patients with severe hypertriglyceridemia Journal of lipid research 2006;47 (10):2333-2339 [PubMed]
  • Oude Elferink Ronald P. J., Paulusma Coen C., Groen Albert K. Hepatocanalicular transport defects: pathophysiologic mechanisms of rare diseases Gastroenterology 2006;130 (3):908-925 [PubMed]
  • Brunham Liam R., Kruit Janine K., Iqbal Jahangir, Fievet Catherine, Timmins Jenelle M., Pape Terry D., Coburn Bryan A., Bissada Nagat, Staels Bart, Groen Albert K., Hussain M. Mahmood, Parks John S., Kuipers Folkert, Hayden Michael R. Intestinal ABCA1 directly contributes to HDL biogenesis in vivo Journal of clinical investigation 2006;116 (4):1052-1062 [PubMed]
  • Jansen P. L. M., Groen A. K. Mechanisms of bile secretionin: T. D. Boyer, T. L. Wright, M. P. Manns, editors. Zakim and Boyer's Hepatology: A textbook of liver disease. Philadelphia, USA: Saunders Elsevier Inc; 2006. p. 67-85, ISBN 9781416032588
  • Gaemers Ingrid C., Groen Albert K. New insights in the pathogenesis of non-alcoholic fatty liver disease Current opinion in lipidology 2006;17 (3):268-273 [PubMed]
  • Groen Albert K. The emerging role of bile acids as integrators of intermediary metabolism Journal of hepatology 2006;45 (2):337-338 [PubMed]
  • Kosters Astrid, Kunne Cindy, Looije Norbert, Patel Shailendra B., Oude Elferink Ronald P. J., Groen Albert K. The mechanism of ABCG5/ABCG8 in biliary cholesterol secretion in mice Journal of lipid research 2006;47 (9):1959-1966 [PubMed]

2005

  • de Vries R., Beusekamp B. J., Kerstens M. N., Groen A. K., van Tol A., Dullaart R. P. F. A low-saturated-fat, low-cholesterol diet decreases plasma CETP activity and pre beta-HDL formation but does not affect cellular cholesterol efflux to plasma from type 1 diabetic patients Scandinavian journal of clinical and laboratory investigation 2005;65 (8):729-737 [PubMed]
  • Hulzebos Christian V., Voshol Peter J., Wolters Henk, Kruit Janine K., Ottenhof Roelof, Groen Albert K., Stellaard Frans, Verkade Henkjan J., Kuipers Folkert Bile duct proliferation associated with bile salt-induced hypercholeresis in Mdr2 P-glycoprotein-deficient mice Liver international 2005;25 (3):604-612 [PubMed]
  • Kosters A. Biliary cholesterol secretion in mice 2005. 171p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Oude Elferink R. P. J.; Co-supervisor: Groen A. K.)
  • de Vries R., Kerstens M. N., Sluiter W. J., Groen A. K., van Tol A., Dullaart R. P. F. Cellular cholesterol efflux to plasma from moderately hypercholesterolaemic type 1 diabetic patients is enhanced, and is unaffected by simvastatin treatment Diabetologia 2005;48 (6):1105-1113 [PubMed]
  • Gustafsson Ulf, Benthin Lisbet, Granström Lars, Groen Albert K., Sahlin Staffan, Einarsson Curt Changes in gallbladder bile composition and crystal detection time in morbidly obese subjects after bariatric surgery Hepatology (Baltimore, Md.) 2005;41 (6):1322-1328 [PubMed]
  • Kosters Astrid, Frijters Raoul J. J. M., Kunne Cindy, Vink Edwin, Schneiders Marit S., Schaap Frank G., Nibbering Catherina P., Patel Shailendra B., Groen Albert K. Diosgenin-induced biliary cholesterol secretion in mice requires Abcg8 Hepatology (Baltimore, Md.) 2005;41 (1):141-150 [PubMed]
  • Kruit Janine K., Plösch Torsten, Havinga Rick, Boverhof Renze, Groot Pieter H. E., Groen Albert K., Kuipers Folkert Increased fecal neutral sterol loss upon liver X receptor activation is independent of biliary sterol secretion in mice Gastroenterology 2005;128 (1):147-156 [PubMed]
  • van Berkel A. M., van Marle J., Groen A. K., Bruno M. J. Mechanisms of biliary stent clogging: Confocal laser scanning and scanning electron microscopy Endoscopy 2005;37 (8):729-734 [PubMed]
  • Hovingh G. K. Molecular defects in the metabolism of the HDL particle and the consequences for atherosclerosis progression 2005. 251p. ISBN 9789090192444. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Kastelein J. J. P.; Co-supervisors: Groen A. K., Kuivenhoven J. A.)
  • van der Veen Jelske N., Kruit Janine K., Havinga Rick, Baller Julius F. W., Chimini Giovanna, Lestavel Sophie, Staels Bart, Groot Pieter H. E., Groen Albert K., Kuipers Folkert Reduced cholesterol absorption upon PPARdelta activation coincides with decreased intestinal expression of NPC1L1 Journal of lipid research 2005;46 (3):526-534 [PubMed]
  • van der Velde Astrid E., Groen Albert K. Shifting gears: liver SR-BI drives reverse cholesterol transport in macrophages Journal of clinical investigation 2005;115 (10):2699-2701 [PubMed]
  • Plösch T., Kosters A., Groen A. K., Kuipers F. The ABC of hepatic and intestinal cholesterol transportin: Handbook Experimental Pharmacology. Berlin, Heidelberg: Springer-Verlag; 2005. p. 465-482
  • Groen Albert K., Oude Elferink Ronald P. J. Treatment modalities for hepatocellular carcinoma Current cancer drug targets 2005;5 (2):131-138 [PubMed]

2004

  • Klett Eric L., Lu Kangmo, Kosters Astrid, Vink Edwin, Lee Mi-Hye, Altenburg Michael, Shefer Sarah, Batta Ashok K., Yu Hongwei, Chen Jianliang, Klein Richard, Looije Norbert, Oude-Elferink Ronald, Groen Albert K., Maeda Nobuyo, Salen Gerald, Patel Shailendra B. A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol BMC medicine 2004;2 (1):5 [PubMed]
  • Schaap Frank G., Rensen Patrick C. N., Voshol Peter J., Vrins Carlos, van der Vliet Hendrik N., Chamuleau Robert A. F. M., Havekes Louis M., Groen Albert K., van Dijk Ko Willems ApoAV reduces plasma triglycerides by inhibiting very low density lipoprotein-triglyceride (VLDL-TG) production and stimulating lipoprotein lipase-mediated VLDL-TG hydrolysis Journal of biological chemistry 2004;279 (27):27941-27947 [PubMed]
  • Bloks V. W., Bakker-van Waarde W. M., Verkade H. J., Kema I. P., Wolters H., Vink E., Groen A. K., Kuipers F. Down-regulation of hepatic and intestinal Abcg5 and Abcg8 expression associated with altered sterol fluxes in rats with streptozotocin-induced diabetes Diabetologia 2004;47 (1):104-112 [PubMed]
  • Hovingh G. K., Kuivenhoven J. A., Bisoendial R. J., Groen A. K., van Dam M., van Tol A., Wellington C., Hayden M. R., Smelt A. H. M., Kastelein J. J. P. HDL deficiency and atherosclerosis: lessons from Tangier disease Journal of internal medicine 2004;255 (2):299-301 [PubMed]
  • vanBerge-Henegouwen G. P., Venneman N. G., Portincasa P., Kosters A., van Erpecum K. J., Groen A. K. Relevance of hereditary defects in lipid transport proteins for the pathogenesis of cholesterol gallstone disease Scandinavian journal of gastroenterology 2004;39 (Suppl. 241):60-69 [PubMed]
  • Plösch Torsten, Bloks Vincent W., Terasawa Yuko, Berdy Sara, Siegler Karen, van der Sluijs Fjodor, Kema Ido P., Groen Albert K., Shan Bei, Kuipers Folkert, Schwarz Margrit, Schwartz Margrit Sitosterolemia in ABC-transporter G5-deficient mice is aggravated on activation of the liver-X receptor Gastroenterology 2004;126 (1):290-300 [PubMed]
  • Plosch T., Bloks V. W., Terasawa Y., Berdy S., Siegler K., van der Sluijs F., Kema I. P., Groen A. K., Shan B., Kuipers F., Schwartz M. Sitosterolemia in ABC-transporter G5-deficient mice is aggravated on activation of the liver-X receptor (Retraction of vol 126, pg 290, 2004) Gastroenterology 2004;126 (3):944
  • Plösch Torsten The ABC of cholesterol transport 2004. 202p. ISBN 9789064641053. [UvA Dissertations Online] University of Groningen: Laboratory of the Department of Pediatrics, Faculty of Medical Sciences. (Supervisor: Kuipers F.; Co-supervisor: Groen A. K.)
  • Groen Albert K., Oude Elferink Ronald P. J., Verkade Henkian J., Kuipers Folkert The ins and outs of reverse cholesterol transport Annals of medicine 2004;36 (2):135-145 [PubMed]

2003

  • Wellington Cheryl L., Brunham Liam R., Zhou Steven, Singaraja Roshni R., Visscher Henk, Gelfer Allison, Ross Colin, James Erick, Liu Guoqing, Huber Mary T., Yang Yu-Zhou, Parks Robin J., Groen Albert, Fruchart-Najib Jamila, Hayden Michael R. Alterations of plasma lipids in mice via adenoviral-mediated hepatic overexpression of human ABCA1 Journal of lipid research 2003;44 (8):1470-1480 [PubMed]
  • Kosters A., Jirsa M., Groen A. K. Genetic background of cholesterol gallstone disease BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 2003;1637 (1):1-19 [PubMed]
  • Goldiner Ilana, Overmars Henk, Groen Albert K., Kulik Willem Method for the quantitative assay of fatty acid-bile acid conjugates by tandem mass spectrometry Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2003;795 (1):35-40 [PubMed]
  • Kosters Astrid, Frijters Raoul J. J. M., Schaap Frank G., Vink Edwin, Plösch Torsten, Ottenhoff Roelof, Jirsa Milan, de Cuyper Iris M., Kuipers Folkert, Groen Albert K. Relation between hepatic expression of ATP-binding cassette transporters G5 and G8 and biliary cholesterol secretion in mice Journal of hepatology 2003;38 (6):710-716 [PubMed]
  • Hovingh G. Kees, van Wijland Michel J. A., Brownlie Alison, Bisoendial Radjesh J., Hayden Michael R., Kastelein John J. P., Groen Albert K. The role of the ABCA1 transporter and cholesterol efflux in familial hypoalphalipoproteinemia Journal of lipid research 2003;44 (6):1251-1255 [PubMed]

2002

  • van der Vliet Hendrik N., Schaap Frank G., Levels Johannes H. M., Ottenhoff Roelof, Looije Norbert, Wesseling John G., Groen Albert K., Chamuleau Robert A. F. M. Adenoviral overexpression of apolipoprotein A-V reduces serum levels of triglycerides and cholesterol in mice Biochemical and biophysical research communications 2002;295 (5):1156-1159 [PubMed]
  • van Dam Marjel J., de Groot Eric, Clee Susanne M., Hovingh G. Kees, Roelants Roosje, Brooks-Wilson Angie, Zwinderman Aeilko H., Smit Andries J., Smelt August H. M., Groen Albert K., Hayden Michael R., Kastelein John J. P. Association between increased arterial-wall thickness and impairment in ABCA1-driven cholesterol efflux: an observational study Lancet 2002;359 (9300):37-41 [PubMed]
  • Elferink R. O., Groen A. K. Genetic defects in hepatobiliary transport BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 2002;1586 (2):129-145 [PubMed]
  • Plōsch Torsten, Kok Tineke, Bloks Vincent W., Smit Martin J., Havinga Rick, Chimini Giovanna, Groen Albert K., Kuipers Folkert Increased hepatobiliary and fecal cholesterol excretion upon activation of the liver X receptor is independent of ABCA1 Journal of biological chemistry 2002;277 (37):33870-33877 [PubMed]
  • Wellington Cheryl L., Yang Yu-Zhou, Zhou Stephen, Clee Susanne M., Tan Bing, Hirano Kenichi, Zwarts Karin, Kwok Anita, Gelfer Allison, Marcil Michel, Newman Scott, Roomp Kirsten, Singaraja Roshni, Collins Jennifer, Zhang Lin-Hua, Groen Albert K., Hovingh Kees, Brownlie Alison, Tafuri Sherrie, Genest Jacques, Kastelein John J. P., Hayden Michael R. Truncation mutations in ABCA1 suppress normal upregulation of full-length ABCA1 by 9-cis-retinoic acid and 22-R-hydroxycholesterol Journal of lipid research 2002;43 (11):1939-1949 [PubMed]

2001

  • Okkes I. M., Groen A., Oskam S. K., Lamberts H. Advantages of long observation in episode-oriented electronic patient records in family practice Methods of information in medicine 2001;40 (3):229-235 [PubMed]
  • van Wijland M. J., de Waart D. R., Groen A. K. Biliary anionic peptide fraction/calcium binding protein inhibits apolipoprotein A-I-mediated cholesterol efflux from cultured cells Biochemical and biophysical research communications 2001;287 (1):1-4 [PubMed]
  • Jirsa M., Muchová L., Dráberová L., Dráber P., Smíd F., Kuroki M., Marecek Z., Groen A. K. Carcinoembryonic antigen-related cell adhesion molecule 1 is the 85-kilodalton pronase-resistant biliary glycoprotein in the cholesterol crystallization promoting low density protein-lipid complex Hepatology (Baltimore, Md.) 2001;34 (6):1075-1082 [PubMed]
  • Voshol P. J., Koopen N. R., de Vree J. M., Havinga R., Princen H. M., Elferink R. P., Groen A. K., Kuipers F. Dietary cholesterol does not normalize low plasma cholesterol levels but induces hyperbilirubinemia and hypercholanemia in Mdr2 P-glycoprotein-deficient mice Journal of hepatology 2001;34 (2):202-209 [PubMed]
  • Voshol P. J., Schwarz M., Rigotti A., Krieger M., Groen A. K., Kuipers F. Down-regulation of intestinal scavenger receptor class B, type I (SR-BI) expression in rodents under conditions of deficient bile delivery to the intestine Biochemical journal 2001;356 (Part 2):317-325 [PubMed]
  • Groen A. K., Bloks V. W., Bandsma R. H., Ottenhoff R., Chimini G., Kuipers F. Hepatobiliary cholesterol transport is not impaired in Abca1-null mice lacking HDL Journal of clinical investigation 2001;108 (6):843-850 [PubMed]
  • Moschetta A., vanBerge-Henegouwen G. P., Portincasa P., Renooij W. L., Groen A. K., van Erpecum K. J. Hydrophilic bile salts enhance differential distribution of sphingomyelin and phosphatidylcholine between micellar and vesicular phases: potential implications for their effects in vivo Journal of hepatology 2001;34 (4):492-499 [PubMed]
  • Miquel J. F., van der Putten J., Pimentel F., Mok K. S., Groen A. K. Increased activity in the biliary Con A-binding fraction accounts for the difference in crystallization behavior in bile from Chilean gallstone patients compared with Dutch gallstone patients Hepatology (Baltimore, Md.) 2001;33 (2):328-332 [PubMed]
  • Nibbering Catherina P. Lipid composition of hepatocyte canalicular membrane: relevance to bile formation 2001. 144p. ISBN 9789039328828. [UvA Dissertations Online] University Utrecht: Department of Gasteoenterology. (Supervisors: van Berge-Henegouwen G. P., Carey M. C.; Co-supervisors: van Erpecum K. J., Groen A. K.)
  • van Erpecum K. J., Wang D. Q., Lammert F., Paigen B., Groen A. K., Carey M. C. Phenotypic characterization of Lith genes that determine susceptibility to cholesterol cholelithiasis in inbred mice: soluble pronucleating proteins in gallbladder and hepatic biles Journal of hepatology 2001;35 (4):444-451 [PubMed]
  • Nibbering C. P., Groen A. K., Ottenhoff R., Brouwers J. F., vanBerge-Henegouwen G. P., van Erpecum K. J. Regulation of biliary cholesterol secretion is independent of hepatocyte canalicular membrane lipid composition: a study in the diosgenin-fed rat model Journal of hepatology 2001;35 (2):164-169 [PubMed]
  • Jirsa M., Groen A. K. Role of biliary proteins and non-protein factors in kinetics of cholesterol crystallisation and gallstone growth Frontiers in bioscience 2001;6:E154-E167 [PubMed]
  • Groen A. K. The pros and cons of gene expression analysis by microarrays Journal of hepatology 2001;35 (2):295-296 [PubMed]

2000

  • A scanning electron microscopic study of biliary stent materials Gastrointestinal endoscopy 2000;51 (1):19-22 [PubMed]
  • Measurement of cholesterol gallstone growth in vitro Journal of lipid research 2000;41 (2):189-194 [PubMed]
  • Mechanisms of biliary lipid secretion and their role in lipid homeostasis Seminars in liver disease 2000;20 (3):293-305 [PubMed]
  • Physiological functions of biliary lipid secretion 2000. 168p. ISBN 9789036711920. [UvA Dissertations Online] University of Groningen: Faculty of Medical Sciences. (Supervisors: Kuipers F., Vonk R. J.; Co-supervisor: Groen A. K.)
  • Postprandial chylomicron formation and fat absorption in multidrug resistance gene 2 P-glycoprotein-deficient mice Gastroenterology 2000;118 (1):173-182 [PubMed]
  • Regulation of biliary lipid secretion 2000. 156p. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Tytgat G. N. J., Borst P.; Co-supervisors: Oude Elferink R. P. J., Groen A. K.)
  • Sphingomyelin exhibits greatly enhanced protection compared with egg yolk phosphatidylcholine against detergent bile salts Journal of lipid research 2000;41 (6):916-924 [PubMed]

1999

  • Concanavalin A-binding cholesterol crystallization inhibiting and promoting activity in bile from patients with Crohn's disease compared to patients with ulcerative colitis Journal of hepatology 1999;31 (4):685-691 [PubMed]
  • Enterohepatic cycling of bilirubin: a putative mechanism for pigment gallstone formation in ileal Crohn's disease Gastroenterology 1999;116 (6):1420-1427 [PubMed]
  • Lack of enteral nutrition during critical illness is associated with profound decrements in biliary lipid concentrations American journal of clinical nutrition 1999;70 (1):70-77 [PubMed]
  • Mucin secretion by the human colon cell line LS174T is regulated by bile salts Glycobiology 1999;9 (1):13-19 [PubMed]
  • Pathogenesis of gallstones in Crohn’s disease 1999. 149p. ISBN 9789090130309. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Tytgat G. N. J., Carey M. C.; Co-supervisor: Groen A. K.)
  • Risk of gallstone disease is associated with serum level of alpha-1-acid glycoprotein Epidemiology (Cambridge, Mass.) 1999;10 (6):764-766 [PubMed]
  • The mechanism of biliary lipid secretion and its defects Gastroenterology clinics of North America 1999;28 (1):59-74, vi [PubMed]
  • The role of different P-glycoproteins in hepatobiliary secretion of fluorescently labeled short-chain phospholipids Journal of lipid research 1999;40 (11):1950-1958 [PubMed]

1998

  • A prospective randomized trial of Teflon versus polyethylene stents for distal malignant biliary obstruction Endoscopy 1998;30 (8):681-686 [PubMed]
  • Cholesterol crystallization in human gallbladder bile: relation to gallstone number, bile composition, and apolipoprotein E4 isoform Hepatology (Baltimore, Md.) 1998;27 (6):1508-1516 [PubMed]
  • Class III P-glycoproteins mediate the formation of lipoprotein X in the mouse Journal of clinical investigation 1998;102 (9):1749-1757 [PubMed]
  • Hepatic bile versus gallbladder bile: a comparison of protein and lipid concentration and composition in cholesterol gallstone patients Hepatology (Baltimore, Md.) 1998;28 (1):11-16 [PubMed]
  • Mucins and calcium phosphate precipitates additively stimulate cholesterol crystallization Journal of lipid research 1998;39 (9):1744-1751 [PubMed]
  • Reduced plasma cholesterol and increased fecal sterol loss in multidrug resistance gene 2 P-glycoprotein-deficient mice Gastroenterology 1998;114 (5):1024-1034 [PubMed]
  • Reversed-phase liquid chromatographic method for the determination of 7-nitrobenz-2-oxa-1,3-diazol-4-yl-labelled lipid analogues Journal of chromatography. B, Biomedical sciences and applications 1998;710 (1-2):9-16 [PubMed]

1997

  • Analysis of occluded pancreatic stents and juices in patients with chronic pancreatitis Gastrointestinal endoscopy 1997;45 (1):52-58 [PubMed]
  • APF/CBP, the small, amphipathic, anionic protein(s) in bile and gallstones, consists of lipid-binding and calcium-binding forms Hepatology (Baltimore, Md.) 1997;25 (5):1054-1063 [PubMed]
  • Biliary manometry, bacterial characteristics, bile composition, and histologic changes fifteen to seventeen years after endoscopic sphincterotomy Gastrointestinal endoscopy 1997;45 (5):400-405 [PubMed]
  • Hepatic canalicular membrane 1: The role of mdr2 P-glycoprotein in hepatobiliary lipid transport FASEB journal 1997;11 (1):19-28 [PubMed]
  • MDR2 P-glycoprotein-mediated lipid secretion and its relevance to biliary drug transport Advanced drug delivery reviews 1997;25 (2-3):201-215
  • Mechanisms and (patho)physiological significance of biliary cholesterol secretion Sub-cellular biochemistry 1997;28 (10):295-318 [PubMed]
  • Mechanistic aspects of cholesterol crystallization in relation to gallstone disease 1997. 97p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Tytgat G. N. J.; Co-supervisor: Groen A. K.)
  • Pathogenesis and treatment of gallstones 1997. 204p. ISBN 9789090106908. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Gouma D. J.; Co-supervisor: Groen A. K.)
  • Regulation of mdr2 P-glycoprotein expression by bile salts Biochemical journal 1997;321 (2):389-395 [PubMed]
  • The role of bile salt composition in liver pathology of mdr2 (-/-) mice: differences between males and females Journal of hepatology 1997;26 (1):138-145 [PubMed]
  • The role of the Concanavalin A-binding fraction in cholesterol crystallization in native human bile Journal of hepatology 1997;27 (6):1041-1050 [PubMed]

1996

  • A novel vesicular assay to study factors affecting cholesterol crystallization in vitro Journal of lipid research 1996;37 (4):877-883 [PubMed]
  • Bile salts and gallbladder mucin secretion - Reply Gastroenterology 1996;110 (1):326
  • Characterization of the cholesterol crystallization-promoting low-density particle isolated from human bile Gastroenterology 1996;110 (6):1936-1944 [PubMed]
  • Control analysis of biliary lipid secretion Journal of theoretical biology 1996;182 (3):427-436 [PubMed]
  • Distinct immuno-localization of mucin and other biliary proteins in human cholesterol gallstones Journal of hepatology 1996;25 (3):339-348 [PubMed]
  • Effects of Ursodeoxycholate and cholate feeding on liver disease in FVB mice with a disrupted mdr2 P-glycoprotein gene Gastroenterology 1996;111 (1):165-171 [PubMed]
  • Gastrointestinal mucins : molecular properties and regulation of secretion 1996. 149p. ISBN 9789090094137. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Tytgat G. N. J.; Co-supervisor: Groen A. K.)
  • Influence of bile salts on hepatic mdr2 P-glycoprotein expression Advances in enzyme regulation 1996;36:351-363 [PubMed]
  • Interactions between organic anions, micelles and vesicles in model bile systems Biochemical journal 1996;320 ( Pt 3):917-923 [PubMed]
  • Mechanism of bile salt-induced mucin secretion by cultured dog gallbladder epithelial cells Biochemical journal 1996;316 (3):873-877 [PubMed]
  • Regulation of canalicular transport activities Journal of hepatology 1996;24 (Suppl. 1):94-99 [PubMed]
  • Relationship between biliary lipid and protoporphyrin secretion; potential role of mdr2 P-glycoprotein in hepatobiliary organic anion transport Journal of hepatology 1996;24 (3):343-352 [PubMed]
  • The pronase resistance of cholesterol-nucleating glycoproteins in human bile Gastroenterology 1996;110 (6):1926-1935 [PubMed]
  • Uncoupling of biliary phospholipid and cholesterol secretion in mice with reduced expression of mdr2 P-glycoprotein Journal of lipid research 1996;37 (5):1065-1075 [PubMed]
  • Ursodeoxycholic acid reduces protein levels and nucleation-promoting activity in human gallbladder bile Gastroenterology 1996;110 (4):1225-1237 [PubMed]

1995

  • Analysis of micellar and vesicular lecithin and cholesterol in model bile using 1H- and 31P-NMR Magma (New York, N.Y.) 1995;3 (2):67-75 [PubMed]
  • Hepatobiliary secretion of organic compounds; molecular mechanisms of membrane transport BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON BIOMEMBRANES 1995;1241 (2):215-268 [PubMed]
  • Interaction of bovine gallbladder mucin and calcium-binding protein: effects on calcium phosphate precipitation Gastroenterology 1995;109 (5):1661-1672 [PubMed]
  • Interaction of cholesterol-crystallization-promoting proteins with vesicles Biochemical journal 1995;305 (1):93-96 [PubMed]
  • Mechanisms of cholesterol gallstone formation Indian journal of gastroenterology 1995;14 (2):59-64 [PubMed]
  • Model bile and bile salts accelerate mucin secretion by cultured dog gallbladder epithelial cells Gastroenterology 1995;109 (1):264-274 [PubMed]
  • New developments in endoscopic biliary and pancreatic drainage 1995. 169p. ISBN 9789090090184. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Tytgat G. N. J.; Co-supervisors: Huibregtse K., Groen A. K.)
  • Quantification of mucin in human gallbladder bile: a fast, specific, and reproducible method Journal of lipid research 1995;36 (11):2450-2458 [PubMed]
  • Rapid association of unconjugated bilirubin with amorphous calcium phosphate Journal of lipid research 1995;36 (8):1697-1707 [PubMed]
  • Regulation of biliary lipid secretion by mdr2 P-glycoprotein in the mouse Journal of clinical investigation 1995;95 (1):31-38 [PubMed]
  • Regulation of protein secretion into bile: studies in mice with a disrupted mdr2 p-glycoprotein gene Gastroenterology 1995;109 (6):1997-2006 [PubMed]
  • The role of mdr2 P-glycoprotein in biliary lipid secretion. Cross-talk between cancer research and biliary physiology Journal of hepatology 1995;23 (5):617-625 [PubMed]

1994

  • Addition of dimethylsulphoxide to methyl-tert-butyl ether and ethyl propionate increases cholesterol dissolving capacity and cholesterol gall stone dissolution in vitro Gut 1994;35 (11):1653-1658 [PubMed]
  • Bile salt-induced cholesterol crystal formation from model bile vesicles: a time course study Journal of lipid research 1994;35 (6):1002-1011 [PubMed]
  • Bile viscosity in patients with biliary drainage. Effect of co-trimoxazole and N-acetylcysteine and role in stent clogging Scandinavian journal of gastroenterology 1994;29 (8):757-763 [PubMed]
  • Crystallization promoting factors in cholesterol gallstone formation 1994. 139p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Tytgat G. N. J.; Co-supervisor: Groen A. K.)
  • Heterogeneity of human biliary mucin: functional implications Clinical science (London, England 1994;86 (1):75-82 [PubMed]
  • Heterogeneity of human gallbladder mucin in bile Clinical science (London, England 1994;86 (1):67-74 [PubMed]
  • Immunoglobulins and alpha 1-acid glycoprotein do not contribute to the cholesterol crystallization-promoting effect of concanavalin A-binding biliary protein Hepatology (Baltimore, Md.) 1994;20 (3):626-632 [PubMed]
  • Mice with homozygous disruption of the mdr2 P-glycoprotein gene. A novel animal model for studies of nonsuppurative inflammatory cholangitis and hepatocarcinogenesis American journal of pathology 1994;145 (5):1237-1245 [PubMed]

1993

  • Biliary endoprostheses: Current indications, limitations and complications 1993. 183p. ISBN 9789090057590. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Tytgat G. N. J.; Co-supervisors: Huibregtse K., Groen A. K.)
  • GALLBLADDER MUCIN AND CHOLESTEROL GALLSTONES European journal of gastroenterology & hepatology 1993;5 (4):226-234
  • Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease Cell 1993;75 (3):451-462 [PubMed]

1992

  • Lytic effects of mixed micelles of fatty acids and bile acids American journal of physiology 1992;263 (3 Part 1):G333-G337 [PubMed]
  • Randomised trial of self-expanding metal stents versus polyethylene stents for distal malignant biliary obstruction Lancet 1992;340 (8834-8835):1488-1492 [PubMed]
  • The validity of the cholesterol nucleation assay BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1992;1138 (1):41-45 [PubMed]

1991

  • Cell type-dependent effect of phospholipid and cholesterol on bile salt cytotoxicity Gastroenterology 1991;101 (2):457-464 [PubMed]

1990

  • ATP-dependent efflux of GSSG and GS-conjugate from isolated rat hepatocytes American journal of physiology 1990;258 (5 Part 1):G699-G706 [PubMed]
  • Clogging of biliary endoprostheses: a new perspective Gut 1990;31 (8):913-917 [PubMed]
  • Endoscopic biliary stenting : mechanisms and possible solutions of the clogging phenomenon 1990. 205p. ISBN 9789052910345. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Tytgat G. N. J.; Co-supervisor: Groen A. K.)
  • Isolation of a potent cholesterol nucleation-promoting activity from human gallbladder bile: role in the pathogenesis of gallstone disease Hepatology (Baltimore, Md.) 1990;11 (4):525-533 [PubMed]
  • Nonmucous glycoproteins as pronucleating agents Hepatology (Baltimore, Md.) 1990;12 (3 Part 2):189S-192S; discussion 192S-194S [PubMed]
  • Use of 1H-NMR to determine the distribution of lecithin between the micellar and vesicular phases in model bile Journal of lipid research 1990;31 (7):1315-1321 [PubMed]

1989

  • An appraisal of the role of biliary phospholipases in the pathogenesis of gallstone disease BIOCHIMICA ET BIOPHYSICA ACTA-LIPIDS AND LIPID METABOLISM 1989;1006 (2):179-182 [PubMed]
  • A placebo-controlled study on the efficacy of aspirin and doxycycline in preventing clogging of biliary endoprostheses Gastrointestinal endoscopy 1989;35 (6):485-489 [PubMed]
  • Effect of cholesterol nucleation-promoting activity on cholesterol solubilization in model bile Journal of lipid research 1989;30 (1):51-58 [PubMed]

1988

  • Cholesterol nucleation and gallstone formation Journal of hepatology 1988;6 (3):383-387 [PubMed]
  • Cholesterol nucleation-influencing activity in T-tube bile Hepatology (Baltimore, Md.) 1988;8 (2):347-352 [PubMed]
  • Control analysis provides a simple means of understanding the control structure of a metabolic pathway Biochemical journal 1988;253 (2):619-621 [PubMed]
  • pH regulation of intracellular membrane flow.in: D. Haussinger, editors. pH homeostatis, mechanisms and control. New York: Academic Press; 1988. p. 123-162, ISBN 9780123330659

1987

  • Characterization of the content of occluded biliary endoprostheses Endoscopy 1987;19 (2):57-59 [PubMed]
  • ENERGY-DEPENDENCE OF AUTOPHAGIC PROTEIN-DEGRADATION IN ISOLATED RAT HEPATOCYTES European Journal of Biochemistry / FEBS 1987;164 (1):197-203 [PubMed]
  • On the origin of the limited control of mitochondrial respiration by the adenine nucleotide translocator Archives of biochemistry and biophysics 1987;257 (1):154-169 [PubMed]
  • Quantification of cholesterol nucleation promoting activity in human gallbladder bile Clinica chimica acta; international journal of clinical chemistry 1987;165 (2-3):295-302 [PubMed]
  • Thermodynamics of the control of metabolism Cell biophysics 1987;11:239-267 [PubMed]

1986

  • CONTROL OF GLUCONEOGENESIS IN RAT-LIVER CELLS - FLUX CONTROL COEFFICIENTS OF THE ENZYMES IN THE GLUCONEOGENIC PATHWAY IN THE ABSENCE AND PRESENCE OF GLUCAGON Biochemical journal 1986;237 (2):379-389 [PubMed]
  • Regulation of mitochondrial respiration in liver Advances in experimental medicine and biology 1986;194:241-254 [PubMed]
  • THE MALATE ASPARTATE SHUTTLE AND PYRUVATE-KINASE AS TARGETS INVOLVED IN THE STIMULATION OF GLUCONEOGENESIS BY PHENYLEPHRINE European Journal of Biochemistry / FEBS 1986;155 (3):551-556 [PubMed]

1985

  • APPLICATION OF CONTROL ANALYSIS IN STUDIES OF REGULATION OF INTERMEDIARY METABOLISM Biomedica biochimica acta 1985;44 (6):943-952 [PubMed]
  • CAN WE AGREE ON METABOLIC CONTROL Trends in biochemical sciences 1985;10 (4):152
  • CONTROL ANALYSIS OF METABOLIC SYSTEMS Trends in biochemical sciences 1985;10 (1):16
  • EFFECTS OF THYROID-HORMONE ON MITOCHONDRIAL OXIDATIVE-PHOSPHORYLATION Biochemical journal 1985;226 (1):183-192 [PubMed]
  • KINETIC-ANALYSIS OF SHORT-TERM EFFECTS OF ALPHA-AGONISTS ON GLUCONEOGENESIS IN ISOLATED RAT HEPATOCYTES FEBS letters 1985;181 (1):43-46 [PubMed]
  • MECHANISM OF THE STIMULATION OF RESPIRATION BY FATTY-ACIDS IN RAT-LIVER FEBS letters 1985;193 (2):243-246 [PubMed]

1984

  • Factors determining the relative contribution of the adenine-nucleotide translocator and the ADP-regenerating system to the control of oxidative phosphorylation in isolated rat-liver mitochondria European Journal of Biochemistry / FEBS 1984;142 (2):417-424 [PubMed]
  • Modern theories of metabolic control and their applications (review) Bioscience reports 1984;4 (1):1-22 [PubMed]

1983

  • Bicarbonate and the pathway of glutamate oxidation in isolated rat-liver mitochondria European Journal of Biochemistry / FEBS 1983;133 (1):245-254 [PubMed]
  • CONTROL OF GLUCONEOGENESIS IN RAT-LIVER CELLS .1. KINETICS OF THE INDIVIDUAL ENZYMES AND THE EFFECT OF GLUCAGON Journal of biological chemistry 1983;258 (23):4346-4353 [PubMed]
  • Control of mitochondrial respiration Biochemical Society transactions 1983;11 (1):40-43 [PubMed]
  • Control of mitochondrial respiration FEBS letters 1983;151 (1):1-9 [PubMed]
  • Measurement of binding of adenine nucleotides and phosphate to cytosolic proteins in permeabilized rat-liver cells European Journal of Biochemistry / FEBS 1983;131 (2):447-451 [PubMed]

1982

  • An evaluation of the metabolite indicator method for determining the cytosolic phosphate potential in rat liver cells BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1982;721 (2):172-177 [PubMed]
  • INTRACELLULAR COMPARTMENTATION AND CONTROL OF ALANINE METABOLISM IN RAT-LIVER PARENCHYMAL-CELLS European Journal of Biochemistry / FEBS 1982;122 (1):87-93 [PubMed]
  • Quantification of the contribution of various steps to the control of mitochondrial respiration Journal of biological chemistry 1982;257 (6):2754-2757 [PubMed]
  • Quantification of the role of the adenine nucleotide translocator in the control of mitochondrial respiration in isolated rat-liver cells FEBS letters 1982;146 (2):262-266 [PubMed]

1981

  • CHARACTERIZATION OF ISOLATED RAT-LIVER CELLS MADE PERMEABLE WITH FILIPIN European Journal of Biochemistry / FEBS 1981;119 (2):409-414 [PubMed]
  • Control mechanisms of energy-dependent metabolic pathways in hepatocytes Acta biologica et medica Germanica 1981;40 (7-8):895-906 [PubMed]
  • Determination of the free-energy difference of the adenine nucleotide translocator reaction in rat-liver mitochondria using intra- and extramitochondrial ATP-utilizing reactions FEBS letters 1981;132 (2):201-206 [PubMed]

1980

  • PLASMA-MEMBRANE TRANSPORT OF ALANINE IS RATE-LIMITING FOR ITS METABOLISM IN RAT-LIVER PARENCHYMAL-CELLS FEBS letters 1980;119 (2):271-274 [PubMed]

1978

  • RELATIONSHIP BETWEEN OXYGEN-UPTAKE OF PERIFUSED RAT-LIVER CELLS AND CYTOSOLIC PHOSPHORYLATION STATE CALCULATED FROM INDICATOR METABOLITES AND A REDETERMINED EQUILIBRIUM-CONSTANT European Journal of Biochemistry / FEBS 1978;84 (2):421-428 [PubMed]