Prof. D.J. Richel PhD publications

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Publications Prof. PhD D.J. Richel

Position
Full Professor
Main activities
Patient care, Research
Specialisation
internal medicin / medical oncology
Focus of research

Clinic: Phase I,II,III clinical studies in cancer patients. Focus on gastrointestinal cancers.

Clinic / laboratory:  Translational research targeted therapy , cell signaling

Laboratory: Cancer Stem cells, Hemostasis and cancer,

 

Amsterdam UMC Research Institutes
AMC departments
All publications

2018

  • Molenaar Remco J., van de Venne Tim, Weterman Mariëtte J., Mathot Ron A., Klümpen Heinz-Josef, Richel Dick J., Wilmink Johanna W. A phase Ib study of everolimus combined with metformin for patients with advanced cancer Investigational new drugs 2018;36 (1):53-61 [PubMed]

2017

  • Laquente Berta, Lopez-Martin Jose, Richards Donald, Illerhaus Gerald, Chang David Z., Kim George, Stella Philip, Richel Dirk, Szcylik Cezary, Cascinu Stefano, Frassineti G. L., Ciuleanu Tudor, Hurt Karla, Hynes Scott, Lin Ji, Lin Aimee Bence, Von Hoff Daniel, Calvo Emiliano A phase II study to evaluate LY2603618 in combination with gemcitabine in pancreatic cancer patients BMC cancer 2017;17 (1):137 [PubMed]
  • Shi Kun, Damhofer Helene, Daalhuisen Joost, ten Brink Marieke, Richel Dick J., Spek C. Arnold Dabigatran Potentiates Gemcitabine-Induced Growth Inhibition of Pancreatic Cancer in Mice Molecular medicine (Cambridge, Mass.) 2017;23:13-23 [PubMed]

2016

  • Schouten Judith, Su Tanja, Wit Ferdinand W., Kootstra Neeltje A., Caan Matthan W. A., Geurtsen Gert J., Schmand Ben A., Stolte Ineke G., Prins Maria, Majoie Charles B., Portegies Peter, Reiss Peter, van der Valk M., Kooij K. W., van Zoest R. A., Elsenga B. C., Prins M., Stolte I. G., Martens M., Moll S., Berkel J., Möller L., Visser G. R., Gras L. A. J., van Leeuwen E., Geerlings S. E., Godfried M. H., Goorhuis A., van der Meer J. T. M., Nellen F. J. B., van der Poll T., Prins J. M., Wiersinga W. J., Postema P. G., Bisschop P. H. L. T., Serlie M. J. M., Dekker E., de Rooij S. E. J. A., Vogt L., van Eck-Smit B. L. F., de Jong M., Richel D. J., Verbraak F. D., Demirkaya N., Ruhé H. G., Nieuwkerk P. T., van Steenwijk R. P., van Lunsen H. W., van den Born B. J. H., Stroes E. S. G. Determinants of reduced cognitive performance in HIV-1-infected middle-aged men on combination antiretroviral therapy AIDS (London, England) 2016;30 (7):1027-1038 [PubMed]
  • Demirkaya Nazli, Wit Ferdinand W. N. M., van den Berg Thomas J. T. P., Kooij Katherine W., Prins Maria, Schlingemann Reinier O., Abramoff Michael D., Reiss Peter, Verbraak Frank D., van der Valk M., Schouten J. [=Judith], van Zoest R. A., Elsenga B. C., Martens M., Moll S., Berkel J., Totté M., Visser G. R., Kovalev S., Kootstra N. A., van Leeuwen E., Geerlings S. E., Godfried M. H., Goorhuis A., Hovius J. W. R., van der Meer J. T. M., Nellen F. J. B., van der Poll T., Prins J. M., Wiersinga W. J., Postema P. G., Bisschop P. H. L. T., Serlie M. J. M., Dekker E., de Rooij S. E. J. A., Vogt L., Portegies P., Schmand B. A., Geurtsen G. J., van Eck-Smit B. L. F., de Jong M., Richel D. J., Ruhé H. G., Nieuwkerk P. T., van Steenwijk R. P., Majoie C. B. L. M., Caan M. W. A., van Lunsen H. W., van den Born B. J. H., Stroes E. S. G. HIV-Associated Neuroretinal Disorder in Patients With Well-Suppressed HIV-Infection: A Comparative Cohort Study Investigative ophthalmology & visual science 2016;57 (3):1388-1397 [PubMed]
  • Kordes Sil Targeted therapies in upper gastrointestinal cancer 2016. 159p. ISBN 9789462332041. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Richel D. J.; Co-supervisor: Wilmink J. W.)
  • Cobos Jiménez Viviana, Wit Ferdinand W. N. M., Joerink Maaike, Maurer Irma, Harskamp Agnes M., Schouten Judith, Prins Maria, van Leeuwen Ester M. M., Booiman Thijs, Deeks Steven G., Reiss Peter, Kootstra Neeltje A., van der Valk M., Kooij K. W., van Zoest R. A., Elsenga B. C., Prins M., Martens M., Boeser-Nunnink B., Geerlings S. E., Godfried M. H., Goorhuis A., Hovius J. W. R., Nellen F. J. B., van der Meer J. T. M., van der Poll T., Prins J. M., Wiersinga W. J., Postema P. G., Bisschop P. H. L. T., Serlie M. J. M., Dekker E., de Rooij S. E. J. A., Vogt L., Portegies P., Schmand B. A., Geurtsen G. J., van Eck-Smit B. L. F., de Jong M., Richel D. J., Verbraak F. D., Demirkaya N., Ruhé H. G., Nieuwkerk P. T., van Steenwijk R. P., Majoie C. B. L. M., Caan M. W. A., van Lunsen H. W., van den Born B. J. H., Stroes E. S. G. T-Cell Activation Independently Associates With Immune Senescence in HIV-Infected Recipients of Long-term Antiretroviral Treatment Journal of infectious diseases 2016;214 (2):216-225 [PubMed]

2015

  • van Linde Myra E., Verhoeff Joost J. C., Richel Dirk J., van Furth Wouter R., Reijneveld Jaap C., Verheul Henk M. W., Stalpers Lukas J. A. Bevacizumab in combination with radiotherapy and temozolomide for patients with newly diagnosed glioblastoma multiforme oncologist 2015;20 (2):107-108 [PubMed]
  • Shi Kun Blood coagulation-(in)dependent protease activated receptor signaling in pancreatic cancer 2015. 189p. ISBN 9789462038226. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Richel D. J.; Co-supervisor: Spek C. A.)
  • Bos Monique M. E. M., Verburg Ilona W. M., Dumaij Ineke, Stouthard Jacqueline, Nortier Johannes W. R., Richel Dick, van der Zwan Eric P. A., de Keizer Nicolette F., de Jonge Evert Intensive care admission of cancer patients: a comparative analysis Cancer medicine 2015;4 (7):966-976 [PubMed]
  • Kordes Sil, Pollak Michael N., Zwinderman Aeilko H., Mathôt Ron A., Weterman Mariëtte J., Beeker Aart, Punt Cornelis J., Richel Dick J., Wilmink Johanna W. Metformin in patients with advanced pancreatic cancer: a double-blind, randomised, placebo-controlled phase 2 trial lancet oncology 2015;16 (7):839-847 [PubMed]
  • Kordes S., Klümpen H. J., Weterman M. J., Schellens J. H. M., Richel D. J., Wilmink J. W. Phase II study of capecitabine and the oral mTOR inhibitor everolimus in patients with advanced pancreatic cancer Cancer chemotherapy and pharmacology 2015;75 (6):1135-1141 [PubMed]

2014

  • Schouten Judith, Wit Ferdinand W., Stolte Ineke G., Kootstra Neeltje A., van der Valk Marc, Geerlings Suzanne E., Prins Maria, Reiss Peter, Kooij K. W., van Zoest R. A., Elsenga B. C., Stolte I. G., Martens M., Moll S., Berkel J., Möller L., Visser G. R., Welling C., Zaheri S., Gras L. A. J., van Leeuwen E., Godfried M. H., Goorhuis A., van der Meer J. T. M., Nellen F. J. B., van der Poll T., Prins J. M., Wiersinga W. J., Postema P. G., Bisschop P. H. L. T., Serlie M. J. M., Dekker E., de Rooij S. E. J. A., Vogt L., Portegies P., Schmand B. A., Geurtsen G. J., van Eck-Smit B. L. F., de Jong M., Richel D. J., Verbraak F. D., Demirkaya N., Ruhé H. G., Nieuwkerk P. T., van Steenwijk R. P., Majoie C. B. L. M., Caan M. W. A., van Lunsen H. W., van den Born B. J. H., Stroes E. S. G. Cross-sectional comparison of the prevalence of age-associated comorbidities and their risk factors between HIV-infected and uninfected individuals: the AGEhIV cohort study Clinical infectious diseases 2014;59 (12):1787-1797 [PubMed]
  • Oppedijk Vera, van der Gaast Ate, van Lanschot Jan J. B., van Hagen Pieter, van Os Rob, van Rij Caroline M., van der Sangen Maurice J., Beukema Jannet C., Rütten Heidi, Spruit Patty H., Reinders Janny G., Richel Dick J., van Berge Henegouwen Mark I., Hulshof Maarten C. C. M. Patterns of recurrence after surgery alone versus preoperative chemoradiotherapy and surgery in the CROSS trials Journal of clinical oncology 2014;32 (5):385-391 [PubMed]
  • Kordes Sil, van Berge Henegouwen Mark I., Hulshof Maarten C., Bergman Jacques J. G. H. M., van der Vliet Hans J., Kapiteijn Ellen, van Laarhoven Hanneke W. M., Richel Dick J., Klinkenbijl Jean H. G., Meijer Sybren L., Wilmink Johanna W. Preoperative chemoradiation therapy in combination with panitumumab for patients with resectable esophageal cancer: the PACT study International journal of radiation oncology, biology, physics 2014;90 (1):190-196 [PubMed]
  • Trip Anouk K., Poppema Boelo J., van Berge Henegouwen Mark I., Siemerink Ester, Beukema Jannet C., Verheij Marcel, Plukker John T. M., Richel Dick J., Hulshof Maarten C. C. M., van Sandick Johanna W., Cats Annemieke, Jansen Edwin P. M., Hospers Geke A. P. Preoperative chemoradiotherapy in locally advanced gastric cancer, a phase I/II feasibility and efficacy study Radiotherapy and oncology 2014;112 (2):284-288 [PubMed]
  • Queiroz Karla C. S., Shi Kun, Duitman Janwillem, Aberson Hella L., Wilmink Johanna W., van Noesel Carel J. M., Richel Dick J., Spek C. Arnold Protease-activated receptor-1 drives pancreatic cancer progression and chemoresistance International journal of cancer. Journal international du cancer 2014;135 (10):2294-2304 [PubMed]
  • Shi Kun, Queiroz Karla C. S., Roelofs Joris J. T. H., van Noesel Carel J. M., Richel Dirk J., Spek C. Arnold Protease-activated receptor 2 suppresses lymphangiogenesis and subsequent lymph node metastasis in a murine pancreatic cancer model Journal of pathology 2014;234 (3):398-409 [PubMed]
  • Heinemann V., Reni M., Ychou M., Richel D. J., Macarulla T., Ducreux M. Tumour-stroma interactions in pancreatic ductal adenocarcinoma: Rationale and current evidence for new therapeutic strategies Cancer treatment reviews 2014;40 (1):118-128 [PubMed]

2013

  • Kordes Sil, Richel Dick J., Klümpen Heinz-Josef, Weterman Mariëtte J., Stevens Arnoldus J. W. M., Wilmink Johanna W. A phase I/II, non-randomized, feasibility/safety and efficacy study of the combination of everolimus, cetuximab and capecitabine in patients with advanced pancreatic cancer Investigational new drugs 2013;31 (1):85-91 [PubMed]
  • Blom R. L. G. M., van Heijl M., Klinkenbijl J. H. G., Bergman J. J. G. H. M., Wilmink J. W., Richel D. J., Hulshof M. C. C. M., Reitsma J. B., Busch O. R. C., van Berge Henegouwen M. I. Neoadjuvant chemoradiotherapy followed by esophagectomy does not increase morbidity in patients over 70 Diseases of the esophagus 2013;26 (5):510-516 [PubMed]
  • van Hagen P., Hulshof M. C. C. M., van Lanschot J. J. B., Steyerberg E. W., van Berge Henegouwen M. I., Wijnhoven B. P. L., Richel D. J., Reinders J. G., Tilanus H. W., van der Gaast A. Preoperatieve chemoradiotherapie voor carcinoom van slokdarm of slokdarm-maagovergang* Nederlands tijdschrift voor geneeskunde 2013;157 (6):A5682 [PubMed]
  • Shi K., Queiroz K. C. S., Stap J., Richel D. J., Spek C. A. Protease-activated receptor-2 induces migration of pancreatic cancer cells in an extracellular ATP-dependent manner Journal of thrombosis and haemostasis 2013;11 (10):1892-1902 [PubMed]

2012

  • Baan Bart, Dihal Ashwin A., Hoff Eva, Bos Carina L., Voorneveld Philip W., Koelink Pim J., Wildenberg Manon E., Muncan Vanesa, Heijmans Jarom, Verspaget Hein W., Richel Dick J., Hardwick James C. H., Hommes Daniel W., Peppelenbosch Maikel P., van den Brink Gijs R. 5-aminosalicylic acid inhibits cell cycle progression in a phospholipase D dependent manner in colorectal cancer Gut 2012;61 (12):1708-1715 [PubMed]
  • Rayson D., Suter T. M., Jackisch C., van der Vegt S., Bermejo B., van den Bosch J., Vivanco G. L., van Gent A. M., Wildiers H., Torres A., Provencher L., Temizkan M., Chirgwin J., Canon J. L., Ferrandina G., Srinivasan S., Zhang L., Richel D. J. Cardiac safety of adjuvant pegylated liposomal doxorubicin with concurrent trastuzumab: a randomized phase II trial Annals of oncology 2012;23 (7):1780-1788 [PubMed]
  • van Doormaal Frederiek F., Kleinjan Ankie, Berckmans René J., Mackman Nigel, Manly David, Kamphuisen Pieter W., Richel Dick J., Büller Harry R., Sturk Auguste, Nieuwland Rienk Coagulation activation anc microparticle-associated coagulant activity in cancer patients An exploratory prospective study Thrombosis and haemostasis 2012;108 (1):160-165 [PubMed]
  • de Jong Joan H., Rodermond Hans M., Zimberlin Cheryl D., Lascano Valeria, de Sousa E Melo Felipe, Richel Dick J., Medema Jan Paul, Vermeulen Louis Fusion of intestinal epithelial cells with bone marrow derived cells is dispensable for tissue homeostasis Scientific reports 2012;2:271 [PubMed]
  • Deenen Maarten J., Klümpen Heinz-Josef, Richel Dick J., Sparidans Rolf W., Weterman Mariette J., Beijnen Jos H., Schellens Jan H. M., Wilmink Johanna W. Phase I and pharmacokinetic study of capecitabine and the oral mTOR inhibitor everolimus in patients with advanced solid malignancies Investigational new drugs 2012;30 (4):1557-1565 [PubMed]
  • van Hagen P., Hulshof M. C. C. M., van Lanschot J. J. B., Steyerberg E. W., van Berge Henegouwen M. I., Wijnhoven B. P. L., Richel D. J., Nieuwenhuijzen G. A. P., Hospers G. A. P., Bonenkamp J. J., Cuesta M. A., Blaisse R. J. B., Busch O. R. C., ten Kate F. J. W., Creemers G.-J., Punt C. J. A., Plukker J. T. M., Verheul H. M. W., Spillenaar Bilgen E. J., van Dekken H., van der Sangen M. J. C., Rozema T., Biermann K., Beukema J. C., Piet A. H. M., van Rij C. M., Reinders J. G., Tilanus H. W., van der Gaast A., Bergman J. J. G. H. M., Bartelsman J. F., Bissumbar A., Blom R. L., Geijsen E. D., van Heijl M., Obertop H., Koning C. C. E., Offerhaus G. J., Omloo J. M., Wilmink H., Aparicio Pages M. N., van den Nieuwenhof-Biesheuvel L., Eijkenboom W. M. H., Koppert L. B., Meijer D. A., Siersema P. D., Spaander M. C. V., Verheij C., Vollebregt C., van Krieken J. H. J. M. Preoperative Chemoradiotherapy for Esophageal or Junctional Cancer New England journal of medicine 2012;366 (22):2074-2084 [PubMed]
  • Vermeulen Louis, de Sousa E Melo Felipe, Richel Dick J., Medema Jan Paul The developing cancer stem-cell model: clinical challenges and opportunities lancet oncology 2012;13 (2):E83-E89 [PubMed]
  • Vermaat Joost S., Gerritse Frank L., van der Veldt Astrid A., Roessingh Wijnand M., Niers Tatjana M., Oosting Sjoukje F., Sleijfer Stefan, Roodhart Jeanine M., Beijnen Jos H., Schellens Jan H., Gietema Jourik A., Boven Epie, Richel Dick J., Haanen John B., Voest Emile E. Validation of Serum Amyloid alpha as an Independent Biomarker for Progression-Free and Overall Survival in Metastatic Renal Cell Cancer Patients European urology 2012;62 (4):685-695 [PubMed]

2011

  • van Heijl M., Phoa S. S. K. S., van Berge Henegouwen M. I., Omloo J. M. T., Mearadji B. M., Sloof G. W., Bossuyt P. M. M., Hulshof M. C. C. M., Richel D. J., Bergman J. J. G. H. M., ten Kate F. J. W., Stoker J., van Lanschot J. J. B. Accuracy and reproducibility of 3D-CT measurements for early response assessment of chemoradiotherapy in patients with oesophageal cancer European journal of surgical oncology 2011;37 (12):1064-1071 [PubMed]
  • Kindler Hedy L., Ioka Tatsuya, Richel Dirk J., Bennouna Jaafar, Létourneau Richard, Okusaka Takuji, Funakoshi Akihiro, Furuse Junji, Park Young Suk, Ohkawa Shinichi, Springett Gregory M., Wasan Harpreet S., Trask Peter C., Bycott Paul, Ricart Alejandro D., Kim Sinil, van Cutsem Eric Axitinib plus gemcitabine versus placebo plus gemcitabine in patients with advanced pancreatic adenocarcinoma: a double-blind randomised phase 3 study lancet oncology 2011;12 (3):256-262 [PubMed]
  • Postema Pieter G., Regeer Madelien V., van der Valk Paul R., Stroes Erik S. G., Richel Dick J. Blue toe syndrome and sunitinib International journal of clinical oncology / Japan Society of Clinical Oncology 2011;16 (5):574-576 [PubMed]
  • van Sluis G. L., Brüggemann L. W., Esmon C. T., Kamphuisen P. W., Richel D. J., Büller H. R., van Noorden C. J. F., Spek C. A. Endogenous activated protein C is essential for immune-mediated cancer cell elimination from the circulation Cancer letters 2011;306 (1):106-110 [PubMed]
  • Beck J., Procopio G., Bajetta E., Keilholz U., Negrier S., Szczylik C., Bokemeyer C., Bracarda S., Richel D. J., Staehler M., Strauss U. P., Mersmann S., Burock K., Escudier B. Final results of the European Advanced Renal Cell Carcinoma Sorafenib (EU-ARCCS) expanded-access study: a large open-label study in diverse community settings Annals of oncology 2011;22 (8):1812-1823 [PubMed]
  • Richel D., de Haes H. Helpen keuzehulpen kiezen? De patient is toenemend betrokkenin: D. T. Ubbink, D. A. Legemate, A. B. Schelfhout, editors. Het bespreken van medische kansen en risico’s. Houten: Bohn Stafleu Van Loghum; 2011. p. 54-66, ISBN 9789031382637
  • de Sousa E Melo Felipe, Colak Selcuk, Buikhuisen Joyce, Koster Jan, Cameron Kate, de Jong Joan H., Tuynman Jurriaan B., Prasetyanti Pramudita R., Fessler Evelyn, van den Bergh Saskia P., Rodermond Hans, Dekker Evelien, van der Loos Chris M., Pals Steven T., van de Vijver Marc J., Versteeg Rogier, Richel Dick J., Vermeulen Louis, Medema Jan Paul Methylation of cancer-stem-cell-associated Wnt target genes predicts poor prognosis in colorectal cancer patients Cell stem cell 2011;9 (5):476-485 [PubMed]
  • Lavini Cristina, Verhoeff Joost J. C., Majoie Charles B., Stalpers Lukas J. A., Richel Dick J., Maas Mario Model-based, semiquantitative and time intensity curve shape analysis of dynamic contrast-enhanced MRI: a comparison in patients undergoing antiangiogenic treatment for recurrent glioma Journal of magnetic resonance imaging 2011;34 (6):1303-1312 [PubMed]
  • Klümpen Heinz-Josef, Queiroz Karla C. S., Spek C. Arnold, van Noesel Carel J. M., Brink Helmy C., de Leng Wendy W. J., de Wilde Roeland F., Mathus-Vliegen Elisabeth M. H., Offerhaus G. Johan A., Alleman Maarten A., Westermann Anneke M., Richel Dirk J. mTOR inhibitor treatment of pancreatic cancer in a patient With Peutz-Jeghers syndrome Journal of clinical oncology 2011;29 (6):e150-e153 [PubMed]
  • van Tienhoven Geertjan, Gouma Dirk J., Richel Dick J. Neoadjuvant chemoradiotherapy has a potential role in pancreatic carcinoma Therapeutic advances in medical oncology 2011;3 (1):27-33 [PubMed]
  • Morak Marjolein J. M., Richel Dick J., van Eijck Casper H. J., Nuyttens Joost J. M. E., van der Gaast Ate, Vervenne Walter L., Padmos Esther E., Schaake Eva E., Busch Olivier R. C., van Tienhoven Geertjan Phase II trial of Uracil/Tegafur plus leucovorin and celecoxib combined with radiotherapy in locally advanced pancreatic cancer Radiotherapy and oncology 2011;98 (2):261-264 [PubMed]
  • van Doormaal Frederiek F., Di Nisio Marcello, Otten Hans-Martin, Richel Dick J., Prins Martin, Buller Harry R. Randomized Trial of the Effect of the Low Molecular Weight Heparin Nadroparin on Survival in Patients With Cancer Journal of clinical oncology 2011;29 (15):2071-2076 [PubMed]
  • de Sousa E Melo Felipe, Vermeulen Louis, Richel Dick, Medema Jan Paul Targeting Wnt Signaling in Colon Cancer Stem Cells Clinical cancer research 2011;17 (4):647-653 [PubMed]
  • Niers Tatjana M. H., Richel Dick J., Meijers Joost C. M., Schlingemann Reinier O. Vascular endothelial growth factor in the circulation in cancer patients may not be a relevant biomarker PLoS ONE 2011;6 (5):e19873 [PubMed]

2010

  • Verhoeff J. J. C., Lavini C., van Linde M. E., Stalpers L. J. A., Majoie C. B. L. M., Reijneveld J. C., van Furth W. R., Richel D. J. Bevacizumab and dose-intense temozolomide in recurrent high-grade glioma Annals of oncology 2010;21 (8):1723-1727 [PubMed]
  • van Sluis Geerte L. Cancer, haemostasis and coagulans 2010. 249p. ISBN 9789090252124. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Büller Harry R., van Noorden C. J. F.; Co-supervisors: Spek C. A., Richel D. J.)
  • Vermeulen Louis Cancer stem cells - a numbers game? 2010. 224p. ISBN 9789090257105. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Medema J. P., Richel D. J.)
  • Rensing K. L., Houttuijn Bloemendaal F. M., Weijers E. M., Richel D. J., Büller H. R., Koolwijk P., van der Loos C. M., Twickler Th B., von der Thüsen J. H. Could recombinant insulin compounds contribute to adenocarcinoma progression by stimulating local angiogenesis? Diabetologia 2010;53 (5):966-970 [PubMed]
  • van Steenbergen L. N., Elferink M. A. G., Krijnen P., Lemmens V. E. P. P., Siesling S., Rutten H. J. T., Richel D. J., Karim-Kos H. E., Coebergh J. W. W. Improved survival of colon cancer due to improved treatment and detection: a nationwide population-based study in The Netherlands 1989-2006 Annals of oncology 2010;21 (11):2206-2212 [PubMed]
  • Tuynman Jurriaan B. Molecular pathways and interventions in GI cancer 2010. 207p. ISBN 9789090255156. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Richel D. J., van Lanschot J. B.; Co-supervisor: Peppelenbosch M. P.)
  • Klerk Clara P. W., Niers Tatjana M. H., Brüggemann Lois W., Smorenburg Susanne M., Richel Dick J., Spek C. Arnold, van Noorden Cornelis J. F. Prophylactic plasma levels of the low molecular weight heparin nadroparin does not affect colon cancer tumor development in mouse liver Thrombosis research 2010;125 (3):235-238 [PubMed]
  • de Kort Susanne J., Pols Jeannette, Richel Dick J., Koedoot Nelleke, Willems Dick L. Understanding palliative cancer chemotherapy: about shared decisions and shared trajectories Health care analysis : HCA 2010;18 (2):164-174 [PubMed]
  • Vermeulen Louis, de Sousa E Melo Felipe, van der Heijden Maartje, Cameron Kate, de Jong Joan H., Borovski Tijana, Tuynman Jurriaan B., Todaro Matilde, Merz Christian, Rodermond Hans, Sprick Martin R., Kemper Kristel, Richel Dick J., Stassi Giorgio, Medema Jan Paul Wnt activity defines colon cancer stem cells and is regulated by the microenvironment Nature cell biology 2010;12 (5):468-U121 [PubMed]

2009

  • de Kort Susanne J. Aims and reasons . Ethical questions about palliative systemic anticancer therapy 2009. 144p. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Willems D. L., Richel D. J.; Co-supervisor: Pols A. J.)
  • Verhoeff J. J. C. Angiogenesis inhibition in high grade glioma 2009. 100p. ISBN 9789490371098. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Richel D. J., Koning C. C. E.; Co-supervisors: van Furth W. R., Stalpers L. J.)
  • Verhoeff Joost J. C., Stalpers Lukas J. A., van Noorden Cornelis J. F., Troost Dirk, Ramkema Marja D., van Bree Chris, Song Ji-Ying, Donker Mila, Chekenya Martha, Vandertop W. Peter, Richel Dick J., van Furth Wouter R. Angiogenesis inhibitor DC101 delays growth of intracerebral glioblastoma but induces morbidity when combined with irradiation Cancer letters 2009;285 (1):39-45 [PubMed]
  • Wülfing Christian, Machiels Jean-Pascal H., Richel Dirk J., Grimm Marc-Oliver, Treiber Uwe, de Groot Marco R., Beuzeboc Philippe, Parikh Roma, Pétavy Frank, El-Hariry Iman A. A Single-arm, Multicenter, Open-label Phase 2 Study of Lapatinib as the Second-line Treatment of Patients With Locally Advanced or Metastatic Transitional Cell Carcinoma Cancer 2009;115 (13):2881-2890 [PubMed]
  • Tol Jolien, Koopman Miriam, Cats Annemieke, Rodenburg Cees J., Creemers Geert J. M., Schrama Jolanda G., Erdkamp Frans L. G., Vos Allert H., van Groeningen Cees J., Sinnige Harm A. M., Richel Dirk J., Voest Emile E., Dijkstra Jeroen R., Vink-Börger Marianne E., Antonini Ninja F., Mol Linda, van Krieken Johan H. J. M., Dalesio Otilia, Punt Cornelis J. A. Chemotherapy, Bevacizumab, and Cetuximab in Metastatic Colorectal Cancer New England journal of medicine 2009;360 (6):563-572 [PubMed]
  • Wind J., Tuynman J. B., Tibbe A. G. J., Swennenhuis J. F., Richel D. J., van Berge Henegouwen M. I., Bemelman W. A. Circulating tumour cells during laparoscopic and open surgery for primary colonic cancer in portal and peripheral blood European journal of surgical oncology 2009;35 (9):942-950 [PubMed]
  • Verhoeff Joost J. C., van Tellingen Olaf, Claes An, Stalpers Lukas J. A., van Linde Myra E., Richel Dirk J., Leenders William P. J., van Furth Wouter R. Concerns about anti-angiogenic treatment in patients with glioblastoma multiforme BMC cancer 2009;9 (1):444 [PubMed]
  • Kuiken Sjoerd D., van Delden Otto M., Richel Dick J., Jansen Peter L. M. De behandeling van het hepatocellulair carcinoom. Nieuwe ontwikkelingen Nederlands tijdschrift voor geneeskunde 2009;153 (14):668-672 [PubMed]
  • Niers Tatjana M. H., Brüggemann Lois W., Klerk Clara P. W., Muller Femke J. M., Buckle Tessa, Reitsma Pieter H., Richel Dick J., Spek C. Arnold, van Tellingen Olaf, van Noorden Cornelis J. F. Differential effects of anticoagulants on tumor development of mouse cancer cell lines B16, K1735 and CT26 in lung Clinical & experimental metastasis 2009;26 (3):171-178 [PubMed]
  • van Sluis Geerte L., Niers Tatjana M. H., Esmon Charles T., Tigchelaar Wikky, Richel Dick J., Buller Harry R., van Noorden Cornelis J. F., Spek C. Arnold Endogenous activated protein C limits cancer cell extravasation through sphingosine-1-phosphate receptor 1-mediated vascular endothelial barrier enhancement Blood 2009;114 (9):1968-1973 [PubMed]
  • Cantaert T., de Rycke L., Mavragani C. P., Wijbrandts C. A., Niewold T. B., Niers T., Vandooren B., Veys E. M., Richel D., Tak P. P., Crow M. K., Baeten D. Exposure to nuclear antigens contributes to the induction of humoral autoimmunity during tumour necrosis factor alpha blockade Annals of the rheumatic diseases 2009;68 (6):1022-1029 [PubMed]
  • Vermeulen Louis, Verhoeff Joost J. C., Richel Dick J., Medema Jan Paul Kankerstamcellen Nederlands tijdschrift voor geneeskunde 2009;153 (7):286-290 [PubMed]
  • Niers T. M. H., Brüggemann L. W., van Sluis G. L., Liu R. D., Versteeg H. H., Büller H. R., van Noorden C. J. F., Reitsma P. H., Spek C. A., Richel D. J. Long-term thrombin inhibition promotes cancer cell extravasation in a mouse model of experimental metastasis Journal of thrombosis and haemostasis 2009;7 (9):1595-1597 [PubMed]
  • Hulshof M. C. C. M., van Haaren P. M. A., van Lanschot J. J. B., Richel D. J., Fockens P., Oldenborg S., Geijsen E. D., van Berge Henegouwen M. I., Crezee J. Preoperative chemoradiation combined with regional hyperthermia for patients with resectable esophageal cancer International journal of hyperthermia 2009;25 (1):79-85 [PubMed]
  • Borovski Tijana, Verhoeff Joost J. C., ten Cate Rosemarie, Cameron Kate, de Vries Nienke A., van Tellingen Olaf, Richel Dirk J., van Furth Wouter R., Medema Jan Paul, Sprick Martin R. Tumor microvasculature supports proliferation and expansion of glioma-propagating cells International journal of cancer. Journal international du cancer 2009;125 (5):1222-1230 [PubMed]
  • Verhoeff Joost J. C., Stalpers Lukas J. A., Claes An, Hovinga Koos E., Musters Gijsbert D., Vandertop W. Peter, Richel Dick J., Leenders William P. J., van Furth Wouter R. Tumour control by whole brain irradiation of anti-VEGF-treated mice bearing intracerebral glioma European journal of cancer (Oxford, England 2009;45 (17):3074-3080 [PubMed]
  • van Doormaal Frederiek F. Venous thromboembolism, coagulation and cancer 2009. 229p. ISBN 9789094901224. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Büller Harry R., Richel Dick J.; Co-supervisor: Otten J. M. M. B.)

2008

  • van Kuilenburg André B. P., Klumpen Heinz-Josef, Westermann Anneke M., Zoetekouw Lida, Bakker Piet J. M., Guchelaar Henk-Jan, Richel Dick J. Altered dihydropyrimidine dehydrogenase activity associated with mild toxicity in patients treated with 5-fluorouracil containing chemotherapy Nucleosides, nucleotides & nucleic acids 2008;27 (6):726-732 [PubMed]
  • de Mulder P. H. M., Haanen J. B. A. G., Sleijfer S., Kruit W. H. J., Gietema J. A., Richel D. J., Groenewegen G., Voest E. E., van den Eertwegh A. J. M., Osanto S., Jansen R. L. H., Mulders P. F. A. Angiogeneseremmers voor de systemische behandeling van gemetastaseerd niercelcarcinoom: sunitinib, sorafenib, bevacizumab en temsirolimus Nederlands tijdschrift voor geneeskunde 2008;152 (7):371-375 [PubMed]
  • Rayson D., Richel D., Chia S., Jackisch C., van der Vegt S., Suter T. Anthracycline-trastuzumab regimens for HER2/neu-overexpressing breast cancer: current experience and future strategies Annals of oncology 2008;19 (9):1530-1539 [PubMed]
  • Peters Natascha A. J. B., Richel Dick J., Verhoeff Joost J. C., Stalpers Lukas J. A. Bowel perforation after radiotherapy in a patient receiving sorafenib Journal of clinical oncology 2008;26 (14):2405-2406 [PubMed]
  • Niers Tatjana M. H. Coagulation, angiogenesis and cancer 2008. 199p. ISBN 9789064642579. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Richel D. J., van Noorden C. J.; Co-supervisors: Büller H. R., Spek C. A.)
  • Tuynman Jurriaan B., Vermeulen Louis, Boon Elles M., Kemper Kristel, Zwinderman Aeilko H., Peppelenbosch Maikel P., Richel Dirk J. Cyclooxygenase-2 inhibition inhibits c-Met kinase activity and Wnt activity in colon cancer Cancer research 2008;68 (4):1213-1220 [PubMed]
  • Tuynman J. B., Lagarde S. M., ten Kate F. J. W., Richel D. J., van Lanschot J. J. B. Met expression is an independent prognostic risk factor in patients with oesophageal adenocarcinoma British journal of cancer 2008;98 (6):1102-1108 [PubMed]
  • van Heijl M., van Lanschot J. J. B., Koppert L. B., van Berge Henegouwen M. I., Muller K., Steyerberg E. W., van Dekken H., Wijnhoven B. P. L., Tilanus H. W., Richel D. J., Busch O. R. C., Bartelsman J. F., Koning C. C. E., Offerhaus G. J., van der Gaast A. Neoadjuvant chemoradiation followed by surgery versus surgery alone for patients with adenocarcinoma or squamous cell carcinoma of the esophagus (CROSS) BMC surgery 2008;8 (1):21 [PubMed]
  • Vermeulen L., Todaro M., de Sousa E Melo F., Sprick M. R., Kemper K., Alea M. Perez, Richel D. J., Stassi G., Medema J. P. Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity Proceedings of the National Academy of Sciences of the United States of America 2008;105 (36):13427-13432 [PubMed]
  • Kweekel D. M., Gelderblom H., van der Straaten T., Antonini N. F., Punt C. J. A., Guchelaar H.-J., van der Hoeven J., Richel D., de Valk B., Douma J., Nieboer P., Valster F., Ras G., Loosveld O., Kehrer D., Bos M., Sinnige H., Knibbeler C., van Deijk W., Sleeboom H., Muller E., Balk E., Creemers G., de Jong R., Zoon P., Wals J., Polee M., Tesselaar M., Brouwer R., de Jong P., Slee P., Oosten H., Kuper M., den Boer M., de Jongh F., Veldhuis G., ten Bokkel Huinink D., van Bochove A. UGT1A1*28 genotype and irinotecan dosage in patients with metastatic colorectal cancer: a Dutch Colorectal Cancer Group study British journal of cancer 2008;99 (2):275-282 [PubMed]

2007

  • Hulsman Niels, Medema Jan Paul, Bos Carina, Jongejan Aldo, Leurs Rob, Smit Martine J., de Esch Iwan J. P., Richel Dick, Wijtmans Maikel Chemical insights in the concept of hybrid drugs: the antitumor effect of nitric oxide-donating aspirin involves a quinone methide but not nitric oxide nor aspirin Journal of medicinal chemistry 2007;50 (10):2424-2431 [PubMed]
  • de Kort Susanne J., Kenny Nuala, van Dijk Paul, Gevers Sjef, Richel Dick J., Willems Dick L. Cost issues in new disease-modifying treatments for advanced cancer: in-depth interviews with physicians European journal of cancer (Oxford, England 2007;43 (13):1983-1989 [PubMed]
  • van Kuilenburg André B. P., Klumpen Heinz-Josef, Westermann Anneke M., Zoetekouw Lida, van Lenthe Henk, Bakker Piet J. M., Richel Dick J., Guchelaar Henk-Jan Increased dihydropyrimidine dehydrogenase activity associated with mild toxicity in patients treated with 5-fluorouracil and leucovorin European journal of cancer (Oxford, England 2007;43 (2):459-465 [PubMed]
  • Terheggen F., Troost D., Majoie C. B., Leenstra S., Richel D. J. Local recurrence and distant metastasis of supratentorial primitive neuro-ectodermal tumor in an adult patient successfully treated with intensive induction chemotherapy and maintenance temozolomide Journal of neuro-oncology 2007;82 (1):113-116 [PubMed]
  • Niers T. M. H., Klerk C. P. W., DiNisio M., van Noorden C. J. F., Büller H. R., Reitsma P. H., Richel D. J. Mechanisms of heparin induced anti-cancer activity in experimental cancer models Critical reviews in oncology/hematology 2007;61 (3):195-207 [PubMed]
  • Lagarde S. M., ten Kate F. J. W., Richel D. J., Offerhaus G. J. A., van Lanschot J. J. B. Molecular prognostic factors in adenocarcinoma of the esophagus and gastroesophageal junction Annals of surgical oncology 2007;14 (2):977-991 [PubMed]
  • Siegel-Lakhai Wandena S., Beijnen Jos H., Vervenne Walter L., Boot Henk, Keessen Marianne, Versola Melissa, Koch Kevin M., Smith Deborah A., Pandite Lini, Richel Dirk J., Schellens Jan H. M. Phase I pharmacokinetic study of the safety and tolerability of lapatinib (GW572016) in combination with oxaliplatin/fluorouracil/leucovorin (FOLFOX4) in patients with solid tumors Clinical cancer research 2007;13 (15 Part 1):4495-4502 [PubMed]
  • Joerger Markus, Huitema Alwin D. R., Richel Dick J., Dittrich Christian, Pavlidis Nikolas, Briasoulis Evangelos, Vermorken Jan B., Strocchi Elena, Martoni Andrea, Sorio Roberto, Sleeboom Henk P., Izquierdo Miguel A., Jodrell Duncan I., Féty Régine, de Bruijn Ernst, Hempel Georg, Karlsson Mats, Tranchand Brigitte, Schrijvers Ad H. G. J., Twelves Chris, Beijnen Jos H., Schellens Jan H. M. Population pharmacokinetics and pharmacodynamics of doxorubicin and cyclophosphamide in breast cancer patients: a study by the EORTC-PAMM-NDDG Clinical pharmacokinetics 2007;46 (12):1051-1068 [PubMed]
  • Joerger Markus, Huitema Alwin D. R., Richel Dick J., Dittrich Christian, Pavlidis Nikolas, Briasoulis Evangelos, Vermorken Jan B., Strocchi Elena, Martoni Andrea, Sorio Roberto, Sleeboom Henk P., Izquierdo Miguel A., Jodrell Duncan I., Calvert Hilary, Boddy Alan V., Hollema Harry, Féty Regine, van der Vijgh Wjf J. F., Hempel Georg, Chatelut Etienne, Karlsson Mats, Wilkins Justin, Tranchand Brigitte, Schrijvers Ad H. G. J., Twelves Christian, Beijnen Jos H., Schellens Jan H. M. Population pharmacokinetics and pharmacodynamics of paclitaxel and carboplatin in ovarian cancer patients: a study by the European organization for research and treatment of cancer-pharmacology and molecular mechanisms group and new drug development group Clinical cancer research 2007;13 (21):6410-6418 [PubMed]
  • Di Nisio Marcello Thrombosis and cancer: advances in diagnosis and prognosis 2007. 212p. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Richel Dick J., Buller Harry R.; Co-supervisor: Middeldorp S.)
  • Klerk Clara P. W., Overmeer Renée M., Niers Tatjana M. H., Versteeg Henri H., Richel Dick J., Buckle Tessa, van Noorden Cornelis J. F., van Tellingen Olaf Validity of bioluminescence measurements for noninvasive in vivo imaging of tumor load in small animals BioTechniques 2007;43 (1 Suppl. S):7-+ [PubMed]

2006

  • Bleuming S. A., Kodach L. L., Garcia Leon M. J., Richel D. J., Peppelenbosch M. P., Reitsma P. H., Hardwick J. C., van den Brink G. R. Altered bone morphogenetic protein signalling in the Helicobacter pylori-infected stomach Journal of pathology 2006;209 (2):190-197 [PubMed]
  • Bos C. L., Kodach L. L., van den Brink G. R., Diks S. H., van Santen M. M., Richel D. J., Peppelenbosch M. P., Hardwick J. C. H. Effect of aspirin on the Wnt/beta-catenin pathway is mediated via protein phosphatase 2A Oncogene 2006;25 (49):6447-6456 [PubMed]
  • de Lange J., van den Akker H. P., van den Berg H., Richel D. J., Gortzak R. A. Th Limited regression of central giant cell granuloma by interferon alpha after failed calcitonin therapy: a report of 2 cases International journal of oral and maxillofacial surgery 2006;35 (9):865-869 [PubMed]
  • Janmaat Maarten L., Gallegos-Ruiz Mariëlle I., Rodriguez José A., Meijer Gerrit A., Vervenne Walter L., Richel Dick J., van Groeningen Cees, Giaccone Giuseppe Predictive factors for outcome in a phase II study of gefitinib in second-line treatment of advanced esophageal cancer patients Journal of clinical oncology 2006;24 (10):1612-1619 [PubMed]
  • Bos Carina L., Diks Sander H., Hardwick James C. H., Walburg Kimberley V., Peppelenbosch Maikel P., Richel Dick J. Protein phosphatase 2A is required for mesalazine-dependent inhibition of Wnt/beta-catenin pathway activity Carcinogenesis 2006;27 (12):2371-2382 [PubMed]
  • de Kort Susanne Joëlle, Willemse Pax H. B., Habraken Jolanda M., de Haes Hanneke C. J. M., Willems Dick L., Richel Dick J. Quality of life versus prolongation of life in patients treated with chemotherapy in advanced colorectal cancer: A review of randomized controlled clinical trials European journal of cancer (Oxford, England 2006;42 (7):835-845 [PubMed]
  • Siersema P. D., Rosenbrand C. J. G. M., Bergman J. J. G. H. M., van der Gaast A., Goedhart C., Richel D. J., Stassen L. P. S., Tilanus H. W. Richtlijn 'Diagnostiek en behandeling oesofaguscarcinoom' Nederlands tijdschrift voor geneeskunde 2006;150 (34):1877-1882 [PubMed]
  • Bos C. L. Signal transduction & drug intervention in colon cancer 2006. 237p. ISBN 9789064640230. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Richel D. J., Peppelenbosch M. P.)

2005

  • Rea D. W., Nortier J. W. R., ten Bokkel Huinink W. W., Falk S., Richel D. J., Maughan T., Groenewegen G., Smit J. M., Steven N., Bakker J. M., Semiond D., Kerr D. J., Punt C. J. A. A phase I/II and pharmacokinetic study of irinotecan in combination with capecitabine as first-line therapy for advanced colorectal cancer Annals of oncology 2005;16 (7):1123-1132 [PubMed]
  • Klerk C. P. W. Cancer, coagulation and thrombotics 2005. 232p. ISBN 9789051709872. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van Noorden C. J. F., Büller H. R.; Co-supervisors: Richel D. J., Smorenburg S. M.)
  • Nieboer Peter, Buijs Ciska, Rodenhuis Sjoerd, Seynaeve Caroline, Beex Louk V. A. M., van der Wall Elsken, Richel Dick J., Nooij Marianne A., Voest Emile E., Hupperets Pierre, Mulder Nanno H., van der Graaf Winette T. A., TenVergert Els M., van Tinteren Harm, de Vries Elisabeth G. E. Fatigue and relating factors in high-risk breast cancer patients treated with adjuvant standard or high-dose chemotherapy: a longitudinal study Journal of clinical oncology 2005;23 (33):8296-8304 [PubMed]
  • Tuynman Jurriaan B., Buskens Christianne J., Kemper Kristel, ten Kate Fiebo J. W., Offerhaus G. Johan A., Richel Dirk J., van Lanschot J. Jan B. Neoadjuvant selective COX-2 inhibition down-regulates important oncogenic pathways in patients with esophageal adenocarcinoma Annals of surgery 2005;242 (6):840-9, discussion 849-50 [PubMed]
  • Klerk Clara P. W., Smorenburg Susanne M., Otten Hans-Martin, Lensing Anthonie W. A., Prins Martin H., Piovella Franco, Prandoni Paolo, Bos Monique M. E. M., Richel Dick J., van Tienhoven Geertjan, Büller Harry R. The effect of low molecular weight heparin on survival in patients with advanced malignancy Journal of clinical oncology 2005;23 (10):2130-2135 [PubMed]

2004

  • Albregts M., Hulshof M. C. C. M., Zum Vörde Sive Vörding P. J., van Lanschot J. J. B., Richel D. J., Crezee H., Fockens P., van Dijk J. D. P., González González D. A feasibility study in oesophageal carcinoma using deep loco-regional hyperthermia combined with concurrent chemotherapy followed by surgery International journal of hyperthermia 2004;20 (6):647-659 [PubMed]
  • Di Nisio Marcello, Squizzato Alessandro, Klerk Clara P. W., Richel Dick J., Büller Harry R. Antithrombotic therapy and cancer Current opinion in hematology 2004;11 (3):187-191 [PubMed]
  • Schoemaker N. E., Kuppens I. E. L. M., Moiseyenko V., Glimelius B., Kjaer M., Starkhammer H., Richel D. J., Smaaland R., Bertelsen K., Poulsen J. P., Voznyi E., Norum J., Fennelly D., Tveit K. M., Garin A., Gruia G., Mourier A., Sibaud D., Lefebvre P., Beijnen J. H., Schellens J. H. M., ten Bokkel Huinink W. W. A randomised phase II multicentre trial of irinotecan (CPT-11) using four different schedules in patients with metastatic colorectal cancer British journal of cancer 2004;91 (8):1434-1441 [PubMed]
  • Schimmel Kirsten J. M., Richel Dick J., van den Brink Renée B. A., Guchelaar Henk-Jan Cardiotoxicity of cytotoxic drugs Cancer treatment reviews 2004;30 (2):181-191 [PubMed]
  • Versteeg Henri H., Spek C. Arnold, Richel Dick J., Peppelenbosch Maikel P. Coagulation factors VIIa and Xa inhibit apoptosis and anoikis Oncogene 2004;23 (2):410-417 [PubMed]
  • Versteeg H. H., Richel D. J., Peppelenbosch M. P., Spek C. A. Concerted action of coagulation factors on cell survival Journal of thrombosis and haemostasis 2004;2 (4):673-674 [PubMed]
  • Tuynman J. B., Peppelenbosch M. P., Richel D. J. COX-2 inhibition as a tool to treat and prevent colorectal cancer Critical reviews in oncology/hematology 2004;52 (2):81-101 [PubMed]
  • Graaf Matthijs R., Richel Dick J., van Noorden Cornelis J. F., Guchelaar Henk-Jan Effects of statins and farnesyltransferase inhibitors on the development and progression of cancer Cancer treatment reviews 2004;30 (7):609-641 [PubMed]
  • Versteeg Henri H., Spek C. Arnold, Slofstra Sjoukje H., Diks Sander H., Richel Dick J., Peppelenbosch Maikel P. FVIIa:TF induces cell survival via G12/G13-dependent Jak/STAT activation and BclXL production Circulation research 2004;94 (8):1032-1040 [PubMed]
  • Diks Sander H., Richel Dick J., Peppelenbosch Maikel P. LPS signal transduction: The picture is becoming more complex Current topics in medicinal chemistry 2004;4 (11):1115-1126 [PubMed]
  • Faneyte Ian F., Peterse Johannes L., van Tinteren Harm, Pronk Corina, Bontenbal Marijike, Beex Louk V. A. M., van der Wall Elsken, Richel Dick J., Nooij Marianne A., Voest Emile E., Hupperets Pierre, ten Vergert Elisabeth M., de Vries Elisabeth G. E., Rodenhuis Sjoerd, van de Vijver Marc J. Predicting early failure after adjuvant chemotherapy in high-risk breast cancer patients with extensive lymph node involvement Clinical cancer research 2004;10 (13):4457-4463 [PubMed]
  • Bos Carina L., Richel Dick J., Ritsema Tita, Peppelenbosch Maikel P., Versteeg Henri H. Prostanoids and prostanoid receptors in signal transduction international journal of biochemistry & cell biology 2004;36 (7):1187-1205 [PubMed]
  • Otten Hans-Martin M. B., Mathijssen Joost, ten Cate Hugo, Soesan Marcel, Inghels Marijke, Richel Dick J., Prins Martin H. Symptomatic venous thromboembolism in cancer patients treated with chemotherapy - An underestimated phenomenon Archives of internal medicine 2004;164 (2):190-194 [PubMed]
  • Richel Dirk J., Vervenne Walter L. Systemic treatment of oesophageal cancer European journal of gastroenterology & hepatology 2004;16 (3):249-254 [PubMed]
  • Graaf Matthijs R., Beiderbeck Annette B., Egberts Antoine C. G., Richel Dick J., Guchelaar Henk-Jan The risk of cancer in users of statins Journal of clinical oncology 2004;22 (12):2388-2394 [PubMed]
  • Versteeg Henri H., Spek C. Arnold, Peppelenbosch Maikel P., Richel Dick J. Tissue factor and cancer metastasis: The role of intracellular and extracellular signaling pathways Molecular medicine (Cambridge, Mass.) 2004;10 (1-6):6-11 [PubMed]

2003

  • Diks Sander H., Hardwick James C., Diab Remco M., van Santen Marije M., Versteeg Henri H., van Deventer Sander J. H., Richel Dick J., Peppelenbosch Maikel P. Activation of the canonical beta-catenin pathway by histamine Journal of biological chemistry 2003;278 (52):52491-52496 [PubMed]
  • Tuynman J. B., Hulscher J. B., Steller E. Ph, van Lanschot J. J., Richel D. J. Cyclo-oxygenase(COX)-2-remming bij de preventie en de behandeling van colorectaal carcinoom Nederlands tijdschrift voor geneeskunde 2003;147 (45):2207-2212 [PubMed]
  • Versteeg H. H. Factor VIIa-induced signal transduction; possible explanations for tissue factor-associated events 2003. 185p. ISBN 9789090168128. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van Deventer S. J. H., Richel D. J.; Co-supervisor: Peppelenbosch M. P.)
  • Rodenhuis Sjoerd, Bontenbal Marijke, Beex Louk V. A. M., Wagstaff John, Richel Dick J., Nooij Marianne A., Voest Emile E., Hupperets Pierre, van Tinteren Harm, Peterse Hans L., TenVergert Elisabeth M., de Vries Elisabeth G. E. High-dose chemotherapy with hematopoietic stem-cell rescue for high-risk breast cancer New England journal of medicine 2003;349 (1):7-16 [PubMed]
  • van Lieshout A. P., van Hillegersberg R., Richel D. J., van Slooten H. J., van Lanschot J. J. Primair adenocarcinoom van de dunne darm Nederlands tijdschrift voor geneeskunde 2003;147 (44):2149-2153 [PubMed]
  • Versteeg H. H., Bresser H. L., Spek C. A., Richel D. J., van Deventer S. J. H., Peppelenbosch M. P. Regulation of the p21Ras-MAP kinase pathway by factor VIIa Journal of thrombosis and haemostasis 2003;1 (5):1012-1018 [PubMed]
  • Buskens C. J., Ristimäki A., Offerhaus G. J. A., Richel D. J., van Lanschot J. J. B. Role of cyclooxygenase-2 in the development and treatment of oesophageal adenocarcinoma Scandinavian journal of gastroenterology 2003;38 (Suppl. 239):87-93 [PubMed]

2002

  • van Lanschot J. Jan B., Aleman Berthe M. P., Richel Dick J. Esophageal carcinoma: surgery, radiotherapy, and chemotherapy Current opinion in gastroenterology 2002;18 (4):490-495 [PubMed]
  • Vervenne Walter L., Bos Carina L., Rens Linda S., Peppelenbosch Maikel P., Richel Dick J. Farnesyl protein transferase inhibition interferes with activation of MAP kinase family members in human peripheral blood monocytes Molecular medicine (Cambridge, Mass.) 2002;8 (12):857-862 [PubMed]
  • Schrama J. G., Faneyte I. F., Schornagel J. H., Baars J. W., Peterse J. L., van de Vijver M. J., Dalesio O., van Tinteren H., Rutgers E. J. T., Richel D. J., Rodenhuis S. Randomized trial of high-dose chemotherapy and hematopoietic progenitor-cell support in operable breast cancer with extensive lymph node involvement: final analysis with 7 years of follow-up Annals of oncology 2002;13 (5):689-698 [PubMed]
  • Otten J. M. M. B. Thrombosis and cancer. A two way association 2002. 135p. ISBN 9789051706499. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Büller H. R., Prins M. H.; Co-supervisors: van Noorden C. J. F., Richel D. J.)
  • Versteeg Henri H., Sørensen Brit B., Slofstra Sjoukje H., van den Brande Jan H. M., Stam Jord C., van Bergen en Henegouwen Paul M. P., Richel Dick J., Petersen Lars C., Peppelenbosch Maikel P. VIIa/tissue factor interaction results in a tissue factor cytoplasmic domain-independent activation of protein synthesis, p70, and p90 S6 kinase phosphorylation Journal of biological chemistry 2002;277 (30):27065-27072 [PubMed]

2001

  • van Kuilenburg A. B., Muller E. W., Haasjes J., Meinsma R., Zoetekouw L., Waterham H. R., Baas F., Richel D. J., van Gennip A. H. Lethal outcome of a patient with a complete dihydropyrimidine dehydrogenase (DPD) deficiency after administration of 5-fluorouracil: frequency of the common IVS14+1G>A mutation causing DPD deficiency Clinical cancer research 2001;7 (5):1149-1153 [PubMed]
  • van Lanschot J. J., González González D., Richel D. J. Surgery, radiotherapy, and chemotherapy for esophageal carcinoma Current opinion in gastroenterology 2001;17 (4):400-405 [PubMed]

2000

  • Tinnemans J. G. M., van Tienhoven G., Richel D. J. Behandeling van kankerHouten Diegem: Bohn Stafleu Van Loghum; 2000. ISBN 9789031330249
  • Tinnemans J. G. M., van Tienhoven G., Richel D. J. Borstkankerin: J. G. M. Tinnemans, G. van Tienhoven, D. J. Richel, editors. Behandeling van kanker. Houten Diegem: Bohn Stafleu Van Loghum; 2000. p. 135-148, ISBN 9789031330249
  • van Kuilenburg A. B., Haasjes J., Richel D. J., Zoetekouw L., van Lenthe H., de Abreu R. A., Maring J. G., Vreken P., van Gennip A. H. Clinical implications of dihydropyrimidine dehydrogenase (DPD) deficiency in patients with severe 5-fluorouracil-associated toxicity: identification of new mutations in the DPD gene Clinical cancer research 2000;6 (12):4705-4712 [PubMed]

1999

  • Lokhorst H. M., Sonneveld P., Cornelissen J. J., Joosten P., van Marwijk Kooy M., Meinema J., Nieuwenhuis H. K., van Oers M. H., Richel D. J., Segeren C. N., Veth G., Verdonck L. F., Wijermans P. W. Induction therapy with vincristine, adriamycin, dexamethasone (VAD) and intermediate-dose melphalan (IDM) followed by autologous or allogeneic stem cell transplantation in newly diagnosed multiple myeloma Bone marrow transplantation 1999;23 (4):317-322 [PubMed]
  • Segeren C. M., Sonneveld P., van der Holt B., Baars J. W., Biesma D. H., Cornellissen J. J., Croockewit A. J., Dekker A. W., Fibbe W. E., Löwenberg B., van Marwijk Kooy M., van Oers M. H., Richel D. J., Schouten H. C., Vellenga E., Verhoef G. E., Wijermans P. W., Wittebol S., Lokhorst H. M. Vincristine, doxorubicin and dexamethasone (VAD) administered as rapid intravenous infusion for first-line treatment in untreated multiple myeloma British journal of haematology 1999;105 (1):127-130 [PubMed]

1998

  • Rodenhuis S., Richel D. J., van der Wall E., Schornagel J. H., Baars J. W., Koning C. C., Peterse J. L., Borger J. H., Nooijen W. J., Bakx R., Dalesio O., Rutgers E. Randomised trial of high-dose chemotherapy and haemopoietic progenitor-cell support in operable breast cancer with extensive axillary lymph-node involvement Lancet 1998;352 (9127):515-521 [PubMed]

1996

  • Baars J. W., Holtkamp M. J., Nooyen W. J., Walll E. V., te Velde A., Dalesio O., Slaper-Cortenbach I. C., Schoot E. V., Richel D. J., Gerritsen W. R., Schornagel J. H., Rodenhuis S. Mobilisation of blood progenitor cells with ifosfamide and etoposide (VP-16) in combination with recombinant human G-CSF (Filgrastim) in patients with malignant lymphomas or solid tumours Anticancer research 1996;16 (5B):3089-3095 [PubMed]
  • van der Wall E., Schaake-Koning C. C., van Zandwijk N., Baars J. W., Schornagel J. H., Richel D. J., Rutgers E. J., Borger J. H., Beijnen J. H., Rodenhuis S. The toxicity of radiotherapy following high-dose chemotherapy with peripheral blood stem cell support in high-risk breast cancer: a preliminary analysis European journal of cancer (Oxford, England 1996;32A (9):1490-1497 [PubMed]

1995

  • van der Wall E., Nooijen W. J., Baars J. W., Holtkamp M. J., Schorangel J. H., Richel D. J., Rutgers E. J., Slaper-Cortenbach I. C., van der Schoot C. E., Rodenhuis S. High-dose carboplatin, thiotepa and cyclophosphamide (CTC) with peripheral blood stem cell support in the adjuvant therapy of high-risk breast cancer: a practical approach British journal of cancer 1995;71 (4):857-862 [PubMed]
  • Dercksen M. W., Weimar I. S., Richel D. J., Breton-Gorius J., Vainchenker W., Slaper-Cortenbach C. M., Pinedo H. M., von dem Borne A. E., Gerritsen W. R., van der Schoot C. E. The value of flow cytometric analysis of platelet glycoprotein expression of CD34+ cells measured under conditions that prevent P-selectin-mediated binding of platelets Blood 1995;86 (10):3771-3782 [PubMed]

1994

  • van der Wall E., Richel D. J., Holtkamp M. J., Slaper-Cortenbach I. C., van der Schoot C. E., Dalesio O., Nooijen W. J., Schornagel J. H., Rodenhuis S. Bone marrow reconstitution after high-dose chemotherapy and autologous peripheral blood progenitor cell transplantation: effect of graft size Annals of oncology 1994;5 (9):795-802 [PubMed]

1993

  • van der Wall E., Richel D. J., Kusumanto Y. H., Rutgers E. J., Schornagel J. H., Schaake-Koning C. C., Peterse J. L., Rodenhuis S. Feasibility study of FEC-chemotherapy with dose-intensive epirubicin as initial treatment in high-risk breast cancer Annals of oncology 1993;4 (9):791-792 [PubMed]
  • Richel D. J., Baars J. W., Wijngaarden M. J., van der Schoot C. E., Vlasveld L. T., Rodenhuis S. Gunstig effect van uit het bloed geïsoleerde hematopoëtische stamcellen op het hematologisch herstel na hooggedoseerde chemotherapie Nederlands tijdschrift voor geneeskunde 1993;137 (5):245-250 [PubMed]

1990

  • Richel D. J., Lepoutre J. M., Kapsenberg J. G., Ooms E. C., Boom W. R., Boucher C. A., Kluin P. M. Epstein-Barr virus in a CD8-positive T-cell lymphoma American journal of pathology 1990;136 (5):1093-1099 [PubMed]
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