Prof. R. Versteeg PhD publications

2021

• Gartlgruber Moritz, Sharma Ashwini Kumar, Quintero Andrés, Dreidax Daniel, Jansky Selina, Park Young-Gyu, Kreth Sina, Meder Johanna, Doncevic Daria, Saary Paul, Toprak Umut H., Ishaque Naveed, Afanasyeva Elena, Wecht Elisa, Koster Jan, Versteeg Rogier, Grünewald Thomas G. P., Jones David T. W., Pfister Stefan M., Henrich Kai-Oliver, van Nes Johan, Herrmann Carl, Westermann Frank Super enhancers define regulatory subtypes and cell identity in neuroblastoma Nature Cancer 2021;2 (1):114-128

2020

• Narayan Ravi S., Molenaar Piet, Teng Jian, Cornelissen Fleur M. G., Roelofs Irene, Menezes Renee, Dik Rogier, Lagerweij Tonny, Broersma Yoran, Petersen Naomi, Marin Soto Jhon Alexander, Brands Eelke, van Kuiken Philip, Lecca Maria C., Lenos Kristiaan J., in ‘t Veld Sjors G. J. G., van Wieringen Wessel, Lang Frederick F., Sulman Erik, Verhaak Roel, Baumert Brigitta G., Stalpers Lucas J. A., Vermeulen Louis, Watts Colin, Bailey David, Slotman Ben J., Versteeg Rogier, Noske David, Sminia Peter, Tannous Bakhos A., Wurdinger Tom, Koster Jan, Westerman Bart A. A cancer drug atlas enables synergistic targeting of independent drug vulnerabilities Nature communications 2020;11 (1) [PubMed]
• van Groningen Tim Intra-tumor heterogeneity and lineage plasticity in neuroblastoma 2020. 191p. ISBN 9789463756617. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Versteeg R.; Co-supervisor: van Nes W. J.)

2019

• Claeys Shana, Denecker Geertrui, Durinck Kaat, Decaesteker Bieke, Mus Liselot M., Loontiens Siebe, Vanhauwaert Suzanne, Althoff Kristina, Wigerup Caroline, Bexell Daniel, Dolman Emmy, Henrich Kai-Oliver, Wehrmann Lea, Westerhout Ellen M., Demoulin Jean-Baptiste, Kumps Candy, van Maerken Tom, Laureys Genevieve, van Neste Christophe, de Wilde Bram, de Wever Olivier, Westermann Frank, Versteeg Rogier, Molenaar Jan J., Påhlman Sven, Schulte Johannes H., de Preter Katleen, Speleman Frank ALK positively regulates MYCN activity through repression of HBP1 expression Oncogene 2019;38 (15):2690-2705 [PubMed]
• van Groningen Tim, Akogul Nurdan, Westerhout Ellen M., Chan Alvin, Hasselt Nancy E., Zwijnenburg Danny A., Broekmans Marloes, Stroeken Peter, Haneveld Franciska, Hooijer Gerrit K. J., Savci-Heijink C. Dilara, Lakeman Arjan, Volckmann Richard, van Sluis Peter, Valentijn Linda J., Koster Jan, Versteeg Rogier, van Nes Johan A NOTCH feed-forward loop drives reprogramming from adrenergic to mesenchymal state in neuroblastoma Nature communications 2019;10 (1):1530 [PubMed]
• van Wezel Esther M. , van Zogchel Lieke M. J. , van Wijk Jalenka, Timmerman Ilse, Vo Ngoc-Kim, Zappeij-Kannegieter Lily, deCarolis Boris, Simon Thorsten, van Noesel Max, Molenaar Jan J. , van Groningen Tim, Versteeg Rogier, Caron Huib N. , van der Schoot C. Ellen, Koster Jan, van Nes Johan, Tytgat Godelieve Mesenchymal Neuroblastoma Cells Are Undetected by Current mRNA Marker Panels: The Development of a Specific Neuroblastoma Mesenchymal Minimal Residual Disease Panel JCO Precision Oncology 2019
• Herold Steffi, Kalb Jacqueline, Büchel Gabriele, Ade Carsten P., Baluapuri Apoorva, Xu Jiajia, Koster Jan, Solvie Daniel, Carstensen Anne, Klotz Christina, Rodewald Sabrina, Schülein-Völk Christina, Dobbelstein Matthias, Wolf Elmar, Molenaar Jan, Versteeg Rogier, Walz Susanne, Eilers Martin Recruitment of BRCA1 limits MYCN-driven accumulation of stalled RNA polymerase Nature 2019;567 (7749):545-549 [PubMed]
• Eleveld Thomas F. The RAS-MAPK pathway in neuroblastoma 2019. 215p. ISBN 9789463754316. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Versteeg R. , Caron H. N.; Co-supervisor: Molenaar J. J.)

2018

• Rajbhandari Presha, Lopez Gonzalo, Capdevila Claudia, Salvatori Beatrice, Yu Jiyang, Rodriguez-Barrueco Ruth, Martinez Daniel, Yarmarkovich Mark, Weichert-Leahey Nina, Abraham Brian J., Alvarez Mariano J., Iyer Archana, Harenza Jo Lynne, Oldridge Derek, de Preter Katleen, Koster Jan, Asgharzadeh Shahab, Seeger Robert C., Wei Jun S., Khan Javed, Vandesompele Jo, Mestdagh Pieter, Versteeg Rogier, Look A. Thomas, Young Richard A., Iavarone Antonio, Lasorella Anna, Silva Jose M., Maris John M., Califano Andrea Cross-cohort analysis identifies a TEAD4–MYCN positive feedback loop as the core regulatory element of high-risk neuroblastoma Cancer discovery 2018;8 (5):582-599 [PubMed]
• Depuydt Pauline, Boeva Valentina, Hocking Toby D., Cannoodt Robrecht, Ambros Inge M., Ambros Peter F., Asgharzadeh Shahab, Attiyeh Edward F., Combaret Valérie, Defferrari Raffaella, Fischer Matthias, Hero Barbara, Hogarty Michael D., Irwin Meredith S., Koster Jan, Kreissman Susan, Ladenstein Ruth, Lapouble Eve, Laureys Geneviève, London Wendy B., Mazzocco Katia, Nakagawara Akira, Noguera Rosa, Ohira Miki, Park Julie R., Pötschger Ulrike, Theissen Jessica, Tonini Gian Paolo, Valteau-Couanet Dominique, Varesio Luigi, Versteeg Rogier, Speleman Frank, Maris John M., Schleiermacher Gudrun, de Preter Katleen Genomic Amplifications and Distal 6q Loss: Novel Markers for Poor Survival in High-risk Neuroblastoma Patients Journal of the National Cancer Institute 2018;110 (10):1084-1093 [PubMed]
• Westendorp B. Florien, Büller Nikè V. J. A., Karpus Olga N., van Dop Willemijn A., Koster Jan, Versteeg Rogier, Koelink Pim J., Snel Clinton Y., Meisner Sander, Roelofs Joris J. T. H., Uhmann Anja, Ver Loren van Themaat Emiel, Heijmans Jarom, Hahn Heidi, Muncan Vanesa, Wildenberg Manon E., van den Brink Gijs R. Indian Hedgehog Suppresses a Stromal Cell-Driven Intestinal Immune Response Cellular and molecular gastroenterology and hepatology 2018;5 (1):67-82.e1 [PubMed]
• Eleveld Thomas F., Schild Linda, Koster Jan, Zwijnenburg Danny A., Alles Lindy K., Ebus Marli E., Volckmann Richard, Tijtgat Godelieve A., van Sluis Peter, Versteeg Rogier, Molenaar Jan J. RaS–MAPK pathway-driven tumor progression is associated with loss of CIC and other genomic aberrations in neuroblastoma Cancer research 2018;78 (21):6297-6307 [PubMed]
• Decaesteker Bieke, Denecker Geertrui, van Neste Christophe, Dolman Emmy M., van Loocke Wouter, Gartlgruber Moritz, Nunes Carolina, de Vloed Fanny, Depuydt Pauline, Verboom Karen, Rombaut Dries, Loontiens Siebe, de Wyn Jolien, Kholosy Waleed M., Koopmans Bianca, Essing Anke H. W., Herrmann Carl, Dreidax Daniel, Durinck Kaat, Deforce Dieter, van Nieuwerburgh Filip, Henssen Anton, Versteeg Rogier, Boeva Valentina, Schleiermacher Gudrun, van Nes Johan, Mestdagh Pieter, Vanhauwaert Suzanne, Schulte Johannes H., Westermann Frank, Molenaar Jan J., de Preter Katleen, Speleman Frank TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets Nature communications 2018;9 (1):4866 [PubMed]

2017

• Bate-Eya Laurel T., Gierman Hinco J., Ebus Marli E., Koster Jan, Caron Huib N., Versteeg Rogier, Dolman M. Emmy M., Molenaar Jan J. Enhancer of zeste homologue 2 plays an important role in neuroblastoma cell survival independent of its histone methyltransferase activity European journal of cancer (Oxford, England 2017;75:63-72 [PubMed]
• van Groningen Tim, Koster Jan, Valentijn Linda J., Zwijnenburg Danny A., Akogul Nurdan, Hasselt Nancy E., Broekmans Marloes, Haneveld Franciska, Nowakowska Natalia E., Bras Johannes, van Noesel Carel J. M., Jongejan Aldo, van Kampen Antoine H., Koster Linda, Baas Frank, van Dijk-Kerkhoven Lianne, Huizer-Smit Margriet, Lecca Maria C., Chan Alvin, Lakeman Arjan, Molenaar Piet, Volckmann Richard, Westerhout Ellen M., Hamdi Mohamed, van Sluis Peter G., Ebus Marli E., Molenaar Jan J., Tytgat Godelieve A., Westerman Bart A., van Nes Johan, Versteeg Rogier Neuroblastoma is composed of two super-enhancer-associated differentiation states Nature genetics 2017;49 (8):1261-1266 [PubMed]

2016

• Johann Pascal D., Erkek Serap, Zapatka Marc, Kerl Kornelius, Buchhalter Ivo, Hovestadt Volker, Jones David T. W., Sturm Dominik, Hermann Carl, Segura Wang Maia, Korshunov Andrey, Rhyzova Marina, Gröbner Susanne, Brabetz Sebastian, Chavez Lukas, Bens Susanne, Gröschel Stefan, Kratochwil Fabian, Wittmann Andrea, Sieber Laura, Geörg Christina, Wolf Stefan, Beck Katja, Oyen Florian, Capper David, van Sluis Peter, Volckmann Richard, Koster Jan, Versteeg Rogier, von Deimling Andreas, Milde Till, Witt Olaf, Kulozik Andreas E., Ebinger Martin, Shalaby Tarek, Grotzer Michael, Sumerauer David, Zamecnik Josef, Mora Jaume, Jabado Nada, Taylor Michael D., Huang Annie, Aronica Eleonora, Bertoni Anna, Radlwimmer Bernhard, Pietsch Torsten, Schüller Ulrich, Schneppenheim Reinhard, Northcott Paul A., Korbel Jan O., Siebert Reiner, Frühwald Michael C., Lichter Peter, Eils Roland, Gajjar Amar, Hasselblatt Martin, Pfister Stefan M., Kool Marcel Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes Cancer cell 2016;29 (3):379-393 [PubMed]
• Matas-Rico Elisa, van Veen Michiel, Leyton-Puig Daniela, van den Berg Jeroen, Koster Jan, Kedziora Katarzyna M., Molenaar Bas, Weerts Marjolein J. A., de Rink Iris, Medema René H., Giepmans Ben N. G., Perrakis Anastassis, Jalink Kees, Versteeg Rogier, Moolenaar Wouter H. Erratum: Glycerophosphodiesterase GDE2 Promotes Neuroblastoma Differentiation through Glypican Release and Is a Marker of Clinical Outcome Cancer cell 2016;30 (6):986 [PubMed]
• Matas-Rico Elisa, van Veen Michiel, Leyton-Puig Daniela, van den Berg Jeroen, Koster Jan, Kedziora Katarzyna M., Molenaar Bas, Weerts Marjolein J. A., de Rink Iris, Medema René H., Giepmans Ben N. G., Perrakis Anastassis, Jalink Kees, Versteeg Rogier, Moolenaar Wouter H. Glycerophosphodiesterase GDE2 Promotes Neuroblastoma Differentiation through Glypican Release and Is a Marker of Clinical Outcome Cancer cell 2016;30 (4):548-562 [PubMed]
• Bate-Eya Laurel T., den Hartog Ilona J. M., van der Ploeg Ida, Schild Linda, Koster Jan, Santo Evan E., Westerhout Ellen M., Versteeg Rogier, Caron Huib N., Molenaar Jan J., Dolman M. Emmy M. High efficacy of the BCL-2 inhibitor ABT199 (venetoclax) in BCL-2 high-expressing neuroblastoma cell lines and xenografts and rational for combination with MCL-1 inhibition Oncotarget 2016;7 (19):27946-27958 [PubMed]
• Fabian Johannes, Opitz Desirée, Althoff Kristina, Lodrini Marco, Hero Barbara, Volland Ruth, Beckers Anneleen, de Preter Katleen, Decock Anneleen, Patil Nitin, Abba Mohammed, Kopp-Schneider Annette, Astrahantseff Kathy, Wünschel Jasmin, Pfeil Sebastian, Ercu Maria, Künkele Annette, Hu Jamie, Thole Theresa, Schweizer Leonille, Mechtersheimer Gunhild, Carter Daniel, Cheung Belamy B., Popanda Odilia, von Deimling Andreas, Koster Jan, Versteeg Rogier, Schwab Manfred, Marshall Glenn M., Speleman Frank, Erb Ulrike, Zoeller Margot, Allgayer Heike, Simon Thorsten, Fischer Matthias, Kulozik Andreas E., Eggert Angelika, Witt Olaf, Schulte Johannes H., Deubzer Hedwig E. MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma Oncotarget 2016;7 (41):66344-66359 [PubMed]
• Sturm Dominik, Orr Brent A., Toprak Umut H., Hovestadt Volker, Jones David T. W., Capper David, Sill Martin, Buchhalter Ivo, Northcott Paul A., Leis Irina, Ryzhova Marina, Koelsche Christian, Pfaff Elke, Allen Sariah J., Balasubramanian Gnanaprakash, Worst Barbara C., Pajtler Kristian W., Brabetz Sebastian, Johann Pascal D., Sahm Felix, Reimand Jüri, Mackay Alan, Carvalho Diana M., Remke Marc, Phillips Joanna J., Perry Arie, Cowdrey Cynthia, Drissi Rachid, Fouladi Maryam, Giangaspero Felice, Łastowska Maria, Grajkowska Wiesława, Scheurlen Wolfram, Pietsch Torsten, Hagel Christian, Gojo Johannes, Lötsch Daniela, Berger Walter, Slavc Irene, Haberler Christine, Jouvet Anne, Holm Stefan, Hofer Silvia, Prinz Marco, Keohane Catherine, Fried Iris, Mawrin Christian, Scheie David, Mobley Bret C., Schniederjan Matthew J., Santi Mariarita, Buccoliero Anna M., Dahiya Sonika, Kramm Christof M., von Bueren André O., von Hoff Katja, Rutkowski Stefan, Herold-Mende Christel, Frühwald Michael C., Milde Till, Hasselblatt Martin, Wesseling Pieter, Rößler Jochen, Schüller Ulrich, Ebinger Martin, Schittenhelm Jens, Frank Stephan, Grobholz Rainer, Vajtai Istvan, Hans Volkmar, Schneppenheim Reinhard, Zitterbart Karel, Collins V. Peter, Aronica Eleonora, Varlet Pascale, Puget Stephanie, Dufour Christelle, Grill Jacques, Figarella-Branger Dominique, Wolter Marietta, Schuhmann Martin U., Shalaby Tarek, Grotzer Michael, van Meter Timothy, Monoranu Camelia-Maria, Felsberg Jörg, Reifenberger Guido, Snuderl Matija, Forrester Lynn Ann, Koster Jan, Versteeg Rogier, Volckmann Richard, van Sluis Peter, Wolf Stephan, Mikkelsen Tom, Gajjar Amar, Aldape Kenneth, Moore Andrew S., Taylor Michael D., Jones Chris, Jabado Nada, Karajannis Matthias A., Eils Roland, Schlesner Matthias, Lichter Peter, von Deimling Andreas, Pfister Stefan M., Ellison David W., Korshunov Andrey, Kool Marcel New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs Cell 2016;164 (5):1060-1072 [PubMed]
• Versteeg Rogier, George Rani E. Targeting ALK: The Ten Lives of a Tumor Cancer discovery 2016;6 (1):20-21 [PubMed]
• Vella Serena, Tavanti Elisa, Hattinger Claudia Maria, Fanelli Marilù, Versteeg Rogier, Koster Jan, Picci Piero, Serra Massimo Targeting CDKs with Roscovitine Increases Sensitivity to DNA Damaging Drugs of Human Osteosarcoma Cells PLoS ONE 2016;11 (11):e0166233 [PubMed]

2015

• Mandriota Stefano J., Valentijn Linda J., Lesne Laurence, Betts David R., Marino Denis, Boudal-Khoshbeen Mary, London Wendy B., Rougemont Anne-Laure, Attiyeh Edward F., Maris John M., Hogarty Michael D., Koster Jan, Molenaar Jan J., Versteeg Rogier, Ansari Marc, Gumy-Pause Fabienne Ataxia-telangiectasia mutated (ATM) silencing promotes neuroblastoma progression through a MYCN independent mechanism Oncotarget 2015;6 (21):18558-18576 [PubMed]
• Dolman M. Emmy M., Poon Evon, Ebus Marli E., den Hartog Ilona J. M., van Noesel Carel J. M., Jamin Yann, Hallsworth Albert, Robinson Simon P., Petrie Kevin, Sparidans Rolf W., Kok Robbert J., Versteeg Rogier, Caron Huib N., Chesler Louis, Molenaar Jan J. Cyclin-Dependent Kinase Inhibitor AT7519 as a Potential Drug for MYCN-Dependent Neuroblastoma Clinical cancer research 2015;21 (22):5100-5109 [PubMed]
• Dolman M. Emmy M., van der Ploeg Ida, Koster Jan, Bate-Eya Laurel Tabe, Versteeg Rogier, Caron Huib N., Molenaar Jan J. DNA-Dependent Protein Kinase As Molecular Target for Radiosensitization of Neuroblastoma Cells PLoS ONE 2015;10 (12):e0145744 [PubMed]
• Santo Evan Edward Forkheads in neuroblastoma & human longevity: From the womb to the tomb 2015. 222p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Versteeg R.; Co-supervisor: Westerhout E. M.)
• von Stedingk Kristoffer, de Preter Katleen, Vandesompele Jo, Noguera Rosa, Øra Ingrid, Koster Jan, Versteeg Rogier, Påhlman Sven, Lindgren David, Axelson Håkan Individual patient risk stratification of high-risk neuroblastomas using a two-gene score suited for clinical use International journal of cancer. Journal international du cancer 2015;137 (4):868-877 [PubMed]
• Mengelbier Linda Holmquist, Karlsson Jenny, Lindgren David, Valind Anders, Lilljebjörn Henrik, Jansson Caroline, Bexell Daniel, Braekeveldt Noémie, Ameur Adam, Jonson Tord, Kultima Hanna Göransson, Isaksson Anders, Asmundsson Jurate, Versteeg Rogier, Rissler Marianne, Fioretos Thoas, Sandstedt Bengt, Börjesson Anna, Backman Torbjörn, Pal Niklas, Øra Ingrid, Mayrhofer Markus, Gisselsson David Intratumoral genome diversity parallels progression and predicts outcome in pediatric cancer Nature communications 2015;6:6125 [PubMed]
• Bleeker Gitta, van Eck-Smit Berthe L., Zwinderman Koos H., Versteeg Rogier, van Noesel Max M., Kam Boen L., Kaspers Gertjan J., van Schie Annelies, Kreissman Susan G., Yanik Gregory, Hero Barbara, Schmidt Matthias, Laureys Geneviève, Lambert Bieke, Øra Ingrid, Schulte Johannes H., Caron Huib N., Tytgat Godelieve A. MIBG scans in patients with stage 4 neuroblastoma reveal two metastatic patterns, one is associated with MYCN amplification and in MYCN-amplified tumours correlates with a better prognosis European journal of nuclear medicine and molecular imaging 2015;42 (2):222-230 [PubMed]
• Pajtler Kristian W., Witt Hendrik, Sill Martin, Jones David T. W., Hovestadt Volker, Kratochwil Fabian, Wani Khalida, Tatevossian Ruth, Punchihewa Chandanamali, Johann Pascal, Reimand Jüri, Warnatz Hans-Jörg, Ryzhova Marina, Mack Steve, Ramaswamy Vijay, Capper David, Schweizer Leonille, Sieber Laura, Wittmann Andrea, Huang Zhiqin, van Sluis Peter, Volckmann Richard, Koster Jan, Versteeg Rogier, Fults Daniel, Toledano Helen, Avigad Smadar, Hoffman Lindsey M., Donson Andrew M., Foreman Nicholas, Hewer Ekkehard, Zitterbart Karel, Gilbert Mark, Armstrong Terri S., Gupta Nalin, Allen Jeffrey C., Karajannis Matthias A., Zagzag David, Hasselblatt Martin, Kulozik Andreas E., Witt Olaf, Collins V. Peter, von Hoff Katja, Rutkowski Stefan, Pietsch Torsten, Bader Gary, Yaspo Marie-Laure, von Deimling Andreas, Lichter Peter, Taylor Michael D., Gilbertson Richard, Ellison David W., Aldape Kenneth, Korshunov Andrey, Kool Marcel, Pfister Stefan M. Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups Cancer cell 2015;27 (5):728-743 [PubMed]
• Wegert Jenny, Ishaque Naveed, Vardapour Romina, Geörg Christina, Gu Zuguang, Bieg Matthias, Ziegler Barbara, Bausenwein Sabrina, Nourkami Nasenien, Ludwig Nicole, Keller Andreas, Grimm Clemens, Kneitz Susanne, Williams Richard D., Chagtai Tas, Pritchard-Jones Kathy, van Sluis Peter, Volckmann Richard, Koster Jan, Versteeg Rogier, Acha Tomas, O'Sullivan Maureen J., Bode Peter K., Niggli Felix, Tytgat Godelieve A., van Tinteren Harm, van den Heuvel-Eibrink Marry M., Meese Eckart, Vokuhl Christian, Leuschner Ivo, Graf Norbert, Eils Roland, Pfister Stefan M., Kool Marcel, Gessler Manfred Mutations in the SIX1/2 Pathway and the DROSHA/DGCR8 miRNA Microprocessor Complex Underlie High-Risk Blastemal Type Wilms Tumors Cancer cell 2015;27 (2):298-311 [PubMed]
• van de Wetering Marc, Francies Hayley E., Francis Joshua M., Bounova Gergana, Iorio Francesco, Pronk Apollo, van Houdt Winan, van Gorp Joost, Taylor-Weiner Amaro, Kester Lennart, McLaren-Douglas Anne, Blokker Joyce, Jaksani Sridevi, Bartfeld Sina, Volckman Richard, van Sluis Peter, Li Vivian S. W., Seepo Sara, Sekhar Pedamallu Chandra, Cibulskis Kristian, Carter Scott L., McKenna Aaron, Lawrence Michael S., Lichtenstein Lee, Stewart Chip, Koster Jan, Versteeg Rogier, van Oudenaarden Alexander, Saez-Rodriguez Julio, Vries Robert G. J., Getz Gad, Wessels Lodewyk, Stratton Michael R., McDermott Ultan, Meyerson Matthew, Garnett Mathew J., Clevers Hans Prospective derivation of a living organoid biobank of colorectal cancer patients Cell 2015;161 (4):933-945 [PubMed]
• Eleveld Thomas F., Oldridge Derek A., Bernard Virginie, Koster Jan, Daage Leo Colmet, Diskin Sharon J., Schild Linda, Bentahar Nadia Bessoltane, Bellini Angela, Chicard Mathieu, Lapouble Eve, Combaret Valérie, Legoix-Né Patricia, Michon Jean, Pugh Trevor J., Hart Lori S., Rader JulieAnn, Attiyeh Edward F., Wei Jun S., Zhang Shile, Naranjo Arlene, Gastier-Foster Julie M., Hogarty Michael D., Asgharzadeh Shahab, Smith Malcolm A., Guidry Auvil Jaime M., Watkins Thomas B. K., Zwijnenburg Danny A., Ebus Marli E., van Sluis Peter, Hakkert Anne, van Wezel Esther, van der Schoot C. Ellen, Westerhout Ellen M., Schulte Johannes H., Tytgat Godelieve A., Dolman M. Emmy M., Janoueix-Lerosey Isabelle, Gerhard Daniela S., Caron Huib N., Delattre Olivier, Khan Javed, Versteeg Rogier, Schleiermacher Gudrun, Molenaar Jan J., Maris John M. Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations Nature genetics 2015;47 (8):864-871 [PubMed]
• Valentijn Linda J., Koster Jan, Zwijnenburg Danny A., Hasselt Nancy E., van Sluis Peter, Volckmann Richard, van Noesel Max M., George Rani E., Tytgat Godelieve A. M., Molenaar Jan J., Versteeg Rogier TERT rearrangements are frequent in neuroblastoma and identify aggressive tumors Nature genetics 2015;47 (12):1411-+ [PubMed]
• Yang Jun, AlTahan Alaa M., Hu Dongli, Wang Yingdi, Cheng Pei-Hsin, Morton Christopher L., Qu Chunxu, Nathwani Amit C., Shohet Jason M., Fotsis Theodore, Koster Jan, Versteeg Rogier, Okada Hitoshi, Harris Adrian L., Davidoff Andrew M. The Role of Histone Demethylase KDM4B in Myc Signaling in Neuroblastoma Journal of the National Cancer Institute 2015;107 (6):djv080 [PubMed]
• van Wezel Esther M., Zwijnenburg Danny, Zappeij-Kannegieter Lily, Bus Erik, van Noesel Max M., Molenaar Jan J., Versteeg Rogier, Fiocco Marta, Caron Huib N., van der Schoot C. Ellen, Koster Jan, Tytgat Godelieve A. M. Whole-genome sequencing identifies patient-specific DNA minimal residual disease markers in neuroblastoma Journal of molecular diagnostics 2015;17 (1):43-52 [PubMed]

2014

• Versteeg Rogier CANCER Tumours outside the mutation box Nature 2014;506 (7489):438-439 [PubMed]
• Rihani Ali, de Wilde Bram, Zeka Fjoralba, Laureys Geneviève, Francotte Nadine, Tonini Gian Paolo, Coco Simona, Versteeg Rogier, Noguera Rosa, Schulte Johannes H., Eggert Angelika, Stallings Raymond L., Speleman Frank, Vandesompele Jo, van Maerken Tom CASP8 SNP D302H (rs1045485) is associated with worse survival in MYCN-amplified neuroblastoma patients PLoS ONE 2014;9 (12):e114696 [PubMed]
• Hovestadt Volker, Jones David T. W., Picelli Simone, Wang Wei, Kool Marcel, Northcott Paul A., Sultan Marc, Stachurski Katharina, Ryzhova Marina, Warnatz Hans-Jörg, Ralser Meryem, Brun Sonja, Bunt Jens, Jäger Natalie, Kleinheinz Kortine, Erkek Serap, Weber Ursula D., Bartholomae Cynthia C., von Kalle Christof, Lawerenz Chris, Eils Jürgen, Koster Jan, Versteeg Rogier, Milde Till, Witt Olaf, Schmidt Sabine, Wolf Stephan, Pietsch Torsten, Rutkowski Stefan, Scheurlen Wolfram, Taylor Michael D., Brors Benedikt, Felsberg Jörg, Reifenberger Guido, Borkhardt Arndt, Lehrach Hans, Wechsler-Reya Robert J., Eils Roland, Yaspo Marie-Laure, Landgraf Pablo, Korshunov Andrey, Zapatka Marc, Radlwimmer Bernhard, Pfister Stefan M., Lichter Peter Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing Nature 2014;510 (7506):537-541 [PubMed]
• Bryan Kenneth, Terrile Marta, Bray Isabella M., Domingo-Fernandéz Raquel, Watters Karen M., Koster Jan, Versteeg Rogier, Stallings Raymond L. Discovery and visualization of miRNA-mRNA functional modules within integrated data using bicluster analysis Nucleic acids research 2014;42 (3):e17 [PubMed]
• Northcott Paul A., Lee Catherine, Zichner Thomas, Stütz Adrian M., Erkek Serap, Kawauchi Daisuke, Shih David J. H., Hovestadt Volker, Zapatka Marc, Sturm Dominik, Jones David T. W., Kool Marcel, Remke Marc, Cavalli Florence M. G., Zuyderduyn Scott, Bader Gary D., VandenBerg Scott, Esparza Lourdes Adriana, Ryzhova Marina, Wang Wei, Wittmann Andrea, Stark Sebastian, Sieber Laura, Seker-Cin Huriye, Linke Linda, Kratochwil Fabian, Jäger Natalie, Buchhalter Ivo, Imbusch Charles D., Zipprich Gideon, Raeder Benjamin, Schmidt Sabine, Diessl Nicolle, Wolf Stephan, Wiemann Stefan, Brors Benedikt, Lawerenz Chris, Eils Jürgen, Warnatz Hans-Jörg, Risch Thomas, Yaspo Marie-Laure, Weber Ursula D., Bartholomae Cynthia C., von Kalle Christof, Turányi Eszter, Hauser Peter, Sanden Emma, Darabi Anna, Siesjö Peter, Sterba Jaroslav, Zitterbart Karel, Sumerauer David, van Sluis Peter, Versteeg Rogier, Volckmann Richard, Koster Jan, Schuhmann Martin U., Ebinger Martin, Grimes H. Leighton, Robinson Giles W., Gajjar Amar, Mynarek Martin, von Hoff Katja, Rutkowski Stefan, Pietsch Torsten, Scheurlen Wolfram, Felsberg Jörg, Reifenberger Guido, Kulozik Andreas E., von Deimling Andreas, Witt Olaf, Eils Roland, Gilbertson Richard J., Korshunov Andrey, Taylor Michael D., Lichter Peter, Korbel Jan O., Wechsler-Reya Robert J., Pfister Stefan M. Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma Nature 2014;511 (7510):428-434 [PubMed]
• Kool Marcel, Jones David T. W., Jäger Natalie, Northcott Paul A., Pugh Trevor J., Hovestadt Volker, Piro Rosario M., Esparza L. Adriana, Markant Shirley L., Remke Marc, Milde Till, Bourdeaut Franck, Ryzhova Marina, Sturm Dominik, Pfaff Elke, Stark Sebastian, Hutter Sonja, Seker-Cin Huriye, Johann Pascal, Bender Sebastian, Schmidt Christin, Rausch Tobias, Shih David, Reimand Jüri, Sieber Laura, Wittmann Andrea, Linke Linda, Witt Hendrik, Weber Ursula D., Zapatka Marc, König Rainer, Beroukhim Rameen, Bergthold Guillaume, van Sluis Peter, Volckmann Richard, Koster Jan, Versteeg Rogier, Schmidt Sabine, Wolf Stephan, Lawerenz Chris, Bartholomae Cynthia C., von Kalle Christof, Unterberg Andreas, Herold-Mende Christel, Hofer Silvia, Kulozik Andreas E., von Deimling Andreas, Scheurlen Wolfram, Felsberg Jörg, Reifenberger Guido, Hasselblatt Martin, Crawford John R., Grant Gerald A., Jabado Nada, Perry Arie, Cowdrey Cynthia, Croul Sydney, Zadeh Gelareh, Korbel Jan O., Doz Francois, Delattre Olivier, Bader Gary D., McCabe Martin G., Collins V. Peter, Kieran Mark W., Cho Yoon-Jae, Pomeroy Scott L., Witt Olaf, Brors Benedikt, Taylor Michael D., Schüller Ulrich, Korshunov Andrey, Eils Roland, Wechsler-Reya Robert J., Lichter Peter, Pfister Stefan M. Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition Cancer cell 2014;25 (3):393-405 [PubMed]
• Barbieri Eveline, de Preter Katleen, Capasso Mario, Chen Zaowen, Hsu Danielle M., Tonini Gian Paolo, Lefever Steve, Hicks John, Versteeg Rogier, Pession Andrea, Speleman Frank, Kim Eugene S., Shohet Jason M. Histone chaperone CHAF1A inhibits differentiation and promotes aggressive neuroblastoma Cancer research 2014;74 (3):765-774 [PubMed]
• Rihani Ali, van Maerken Tom, de Wilde Bram, Zeka Fjoralba, Laureys Geneviève, Norga Koen, Tonini Gian Paolo, Coco Simona, Versteeg Rogier, Noguera Rosa, Schulte Johannes H., Eggert Angelika, Stallings Raymond L., Speleman Frank, Vandesompele Jo Lack of association between MDM2 promoter SNP309 and clinical outcome in patients with neuroblastoma Pediatric blood & cancer 2014;61 (10):1867-1870 [PubMed]
• Bate-Eya Laurel T., Ebus Marli E., Koster Jan, den Hartog Ilona J. M., Zwijnenburg Danny A., Schild Linda, van der Ploeg Ida, Dolman M. Emmy M., Caron Huib N., Versteeg Rogier, Molenaar Jan J. Newly-derived neuroblastoma cell lines propagated in serum-free media recapitulate the genotype and phenotype of primary neuroblastoma tumours European journal of cancer (Oxford, England 2014;50 (3):628-637 [PubMed]
• Lee Sangkyun, Rahnenführer Jörg, Lang Michel, de Preter Katleen, Mestdagh Pieter, Koster Jan, Versteeg Rogier, Stallings Raymond L., Varesio Luigi, Asgharzadeh Shahab, Schulte Johannes H., Fielitz Kathrin, Schwermer Melanie, Morik Katharina, Schramm Alexander Robust selection of cancer survival signatures from high-throughput genomic data using two-fold subsampling PLoS ONE 2014;9 (10):e108818 [PubMed]
• Verhaegh Wim, van Ooijen Henk, Inda Márcia A., Hatzis Pantelis, Versteeg Rogier, Smid Marcel, Martens John, Foekens John, van de Wiel Paul, Clevers Hans, van de Stolpe Anja Selection of personalized patient therapy through the use of knowledge-based computational models that identify tumor-driving signal transduction pathways Cancer research 2014;74 (11):2936-2945 [PubMed]
• Sero Valeria, Tavanti Elisa, Vella Serena, Hattinger Claudia Maria, Fanelli Marilù, Michelacci Francesca, Versteeg Rogier, Valsasina Barbara, Gudeman Beth, Picci Piero, Serra Massimo Targeting polo-like kinase 1 by NMS-P937 in osteosarcoma cell lines inhibits tumor cell growth and partially overcomes drug resistance Investigational new drugs 2014;32 (6):1167-1180 [PubMed]
• Cangelosi Davide, Muselli Marco, Parodi Stefano, Blengio Fabiola, Becherini Pamela, Versteeg Rogier, Conte Massimo, Varesio Luigi Use of Attribute Driven Incremental Discretization and Logic Learning Machine to build a prognostic classifier for neuroblastoma patients BMC bioinformatics 2014;15 (Suppl. 5):S4 [PubMed]

2013

• van Nes Johan, Chan Alvin, van Groningen Tim, van Sluis Peter, Koster Jan, Versteeg Rogier A NOTCH3 transcriptional module induces cell motility in neuroblastoma Clinical cancer research 2013;19 (13):3485-3494 [PubMed]
• Zeilstra Jurrit, Joosten Sander P. J., Vermeulen Louis, Koster Jan, Medema Jan Paul, Versteeg Rogier, Spaargaren Marcel, Pals Steven T. CD44 expression in intestinal epithelium and colorectal cancer is independent of p53 status PLoS ONE 2013;8 (8):e72849 [PubMed]
• Wilzén Annica, Krona Cecilia, Sveinbjörnsson Baldur, Kristiansson Erik, Dalevi Daniel, Øra Ingrid, de Preter Katleen, Stallings Raymond L., Maris John, Versteeg Rogier, Nilsson Staffan, Kogner Per, Abel Frida ERBB3 is a marker of a ganglioneuroblastoma/ganglioneuroma-like expression profile in neuroblastic tumours Molecular cancer 2013;12 (1):70 [PubMed]
• Santo Evan E., Stroeken Peter, Sluis Peter V., Koster Jan, Versteeg Rogier, Westerhout Ellen M. FOXO3a is a major target of inactivation by PI3K/AKT signaling in aggressive neuroblastoma Cancer research 2013;73 (7):2189-2198 [PubMed]
• Jäger Natalie, Schlesner Matthias, Jones David T. W., Raffel Simon, Mallm Jan-Philipp, Junge Kristin M., Weichenhan Dieter, Bauer Tobias, Ishaque Naveed, Kool Marcel, Northcott Paul A., Korshunov Andrey, Drews Ruben M., Koster Jan, Versteeg Rogier, Richter Julia, Hummel Michael, Mack Stephen C., Taylor Michael D., Witt Hendrik, Swartman Benedict, Schulte-Bockholt Dietrich, Sultan Marc, Yaspo Marie-Laure, Lehrach Hans, Hutter Barbara, Brors Benedikt, Wolf Stephan, Plass Christoph, Siebert Reiner, Trumpp Andreas, Rippe Karsten, Lehmann Irina, Lichter Peter, Pfister Stefan M., Eils Roland Hypermutation of the inactive X chromosome is a frequent event in cancer Cell 2013;155 (3):567-581 [PubMed]
• Lundberg Gisela, Jin Yuesheng, Sehic Daniel, Øra Ingrid, Versteeg Rogier, Gisselsson David Intratumour diversity of chromosome copy numbers in neuroblastoma mediated by on-going chromosome loss from a polyploid state PLoS ONE 2013;8 (3):e59268 [PubMed]
• Cangelosi Davide, Blengio Fabiola, Versteeg Rogier, Eggert Angelika, Garaventa Alberto, Gambini Claudio, Conte Massimo, Eva Alessandra, Muselli Marco, Varesio Luigi Logic Learning Machine creates explicit and stable rules stratifying neuroblastoma patients BMC bioinformatics 2013;14 (Suppl. 7):S12 [PubMed]
• Das S., Bryan K., Buckley P. G., Piskareva O., Bray I. M., Foley N., Ryan J., Lynch J., Creevey L., Fay J., Prenter S., Koster J., van Sluis P., Versteeg R., Eggert A., Schulte J. H., Schramm A., Mestdagh P., Vandesompele J., Speleman F., Stallings R. L. Modulation of neuroblastoma disease pathogenesis by an extensive network of epigenetically regulated microRNAs Oncogene 2013;32 (24):2927-2936 [PubMed]
• Schulte J. H., Lindner S., Bohrer A., Maurer J., de Preter K., Lefever S., Heukamp L., Schulte S., Molenaar J., Versteeg R., Thor T., Künkele A., Vandesompele J., Speleman F., Schorle H., Eggert A., Schramm A. MYCN and ALKF1174L are sufficient to drive neuroblastoma development from neural crest progenitor cells Oncogene 2013;32 (8):1059-1065 [PubMed]
• Bunt Jens, Hasselt Nancy A., Zwijnenburg Danny A., Koster Jan, Versteeg Rogier, Kool Marcel OTX2 sustains a bivalent-like state of OTX2-bound promoters in medulloblastoma by maintaining their H3K27me3 levels Acta neuropathologica 2013;125 (3):385-394 [PubMed]
• Tavanti E., Sero V., Vella S., Fanelli M., Michelacci F., Landuzzi L., Magagnoli G., Versteeg R., Picci P., Hattinger C. M., Serra M. Preclinical validation of Aurora kinases-targeting drugs in osteosarcoma British journal of cancer 2013;109 (10):2607-2618 [PubMed]
• Jones David T. W., Hutter Barbara, Jäger Natalie, Korshunov Andrey, Kool Marcel, Warnatz Hans-Jörg, Zichner Thomas, Lambert Sally R., Ryzhova Marina, Quang Dong Anh Khuong, Fontebasso Adam M., Stütz Adrian M., Hutter Sonja, Zuckermann Marc, Sturm Dominik, Gronych Jan, Lasitschka Bärbel, Schmidt Sabine, Seker-Cin Huriye, Witt Hendrik, Sultan Marc, Ralser Meryem, Northcott Paul A., Hovestadt Volker, Bender Sebastian, Pfaff Elke, Stark Sebastian, Faury Damien, Schwartzentruber Jeremy, Majewski Jacek, Weber Ursula D., Zapatka Marc, Raeder Benjamin, Schlesner Matthias, Worth Catherine L., Bartholomae Cynthia C., von Kalle Christof, Imbusch Charles D., Radomski Sylwester, Lawerenz Chris, van Sluis Peter, Koster Jan, Volckmann Richard, Versteeg Rogier, Lehrach Hans, Monoranu Camelia, Winkler Beate, Unterberg Andreas, Herold-Mende Christel, Milde Till Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma Nature genetics 2013;45 (8):927-932 [PubMed]
• von Stedingk Kristoffer, Koster Jan, Piqueras Marta, Noguera Rosa, Navarro Samuel, Påhlman Sven, Versteeg Rogier, Ora Ingrid, Gisselsson David, Lindgren David, Axelson Håkan snoRNPs Regulate Telomerase Activity in Neuroblastoma and Are Associated with Poor Prognosis Translational oncology 2013;6 (4):447-U142 [PubMed]
• Molenaar J. J., Koster J., Ebus M., Zwijnenburg D. A., van Sluis P., Lamers F., Schild L., van der Ploeg I., Caron H. N., Versteeg R. Targeted Drug Development in Pediatric Cancer Despite a Low Frequency of Tumor Driving Mutations Annals of oncology 2013;24:i7
• Kocemba K. A., van Andel H., de Haan-Kramer A., Mahtouk K., Versteeg R., Kersten M. J., Spaargaren M., Pals S. T. The hypoxia target adrenomedullin is aberrantly expressed in multiple myeloma and promotes angiogenesis Leukemia 2013;27 (8):1729-1737 [PubMed]

2012

• Orlova Darya Yu, Stixová Lenka, Kozubek Stanislav, Gierman Hinco J., Šustáčková Gabriela, Chernyshev Andrei V., Medvedev Ruslan N., Legartová Soňa, Versteeg Rogier, Matula Pavel, Stoklasa Roman, Bártová Eva Arrangement of nuclear structures is not transmitted through mitosis but is identical in sister cells Journal of cellular biochemistry 2012;113 (11):3313-3329 [PubMed]
• Molenaar Jan J., Koster Jan, Ebus Marli E., van Sluis Peter, Westerhout Ellen M., de Preter Katleen, Gisselsson David, Øra Ingrid, Speleman Frank, Caron Huib N., Versteeg Rogier Copy Number Defects of G1-Cell Cycle Genes in Neuroblastoma are Frequent and Correlate with High Expression of E2F Target Genes and a Poor Prognosis Genes, chromosomes & cancer 2012;51 (1):10-19 [PubMed]
• Cornero Andrea, Acquaviva Massimo, Fardin Paolo, Versteeg Rogier, Schramm Alexander, Eva Alessandra, Bosco Maria Carla, Blengio Fabiola, Barzaghi Sara, Varesio Luigi Design of a multi-signature ensemble classifier predicting neuroblastoma patients' outcome BMC bioinformatics 2012;13 (4):S13 [PubMed]
• Schramm A., Schowe B., Fielitz K., Heilmann M., Martin M., Marschall T., Köster J., Vandesompele J., Vermeulen J., de Preter K., Koster J., Versteeg R., Noguera R., Speleman F., Rahmann S., Eggert A., Morik K., Schulte J. H. Exon-level expression analyses identify MYCN and NTRK1 as major determinants of alternative exon usage and robustly predict primary neuroblastoma outcome British journal of cancer 2012;107 (8):1409-1417 [PubMed]
• Valentijn Linda J., Koster Jan, Haneveld Franciska, Aissa Rachida Ait, van Sluis Peter, Broekmans Marloes E. C., Molenaar Jan J., van Nes Johan, Versteeg Rogier Functional MYCN signature predicts outcome of neuroblastoma irrespective of MYCN amplification Proceedings of the National Academy of Sciences of the United States of America 2012;109 (47):19190-19195 [PubMed]
• Rausch Tobias, Jones David T. W., Zapatka Marc, Stütz Adrian M., Zichner Thomas, Weischenfeldt Joachim, Jäger Natalie, Remke Marc, Shih David, Northcott Paul A., Pfaff Elke, Tica Jelena, Wang Qi, Massimi Luca, Witt Hendrik, Bender Sebastian, Pleier Sabrina, Cin Huriye, Hawkins Cynthia, Beck Christian, von Deimling Andreas, Hans Volkmar, Brors Benedikt, Eils Roland, Scheurlen Wolfram, Blake Jonathon, Benes Vladimir, Kulozik Andreas E., Witt Olaf, Martin Dianna, Zhang Cindy, Porat Rinnat, Merino Diana M., Wasserman Jonathan, Jabado Nada, Fontebasso Adam, Bullinger Lars, Rücker Frank G., Döhner Konstanze, Döhner Hartmut, Koster Jan, Molenaar Jan J., Versteeg Rogier, Kool Marcel, Tabori Uri, Malkin David, Korshunov Andrey, Taylor Michael D., Lichter Peter, Pfister Stefan M., Korbel Jan O. Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations Cell 2012;148 (1-2):59-71 [PubMed]
• Sturm Dominik, Witt Hendrik, Hovestadt Volker, Khuong-Quang Dong-Anh, Jones David T. W., Konermann Carolin, Pfaff Elke, Tönjes Martje, Sill Martin, Bender Sebastian, Kool Marcel, Zapatka Marc, Becker Natalia, Zucknick Manuela, Hielscher Thomas, Liu Xiao-Yang, Fontebasso Adam M., Ryzhova Marina, Albrecht Steffen, Jacob Karine, Wolter Marietta, Ebinger Martin, Schuhmann Martin U., van Meter Timothy, Frühwald Michael C., Hauch Holger, Pekrun Arnulf, Radlwimmer Bernhard, Niehues Tim, von Komorowski Gregor, Dürken Matthias, Kulozik Andreas E., Madden Jenny, Donson Andrew, Foreman Nicholas K., Drissi Rachid, Fouladi Maryam, Scheurlen Wolfram, von Deimling Andreas, Monoranu Camelia, Roggendorf Wolfgang, Herold-Mende Christel, Unterberg Andreas, Kramm Christof M., Felsberg Jörg, Hartmann Christian, Wiestler Benedikt, Wick Wolfgang, Milde Till, Witt Olaf, Lindroth Anders M., Schwartzentruber Jeremy, Faury Damien, Fleming Adam, Zakrzewska Magdalena, Liberski Pawel P., Zakrzewski Krzysztof, Hauser Peter, Garami Miklos, Klekner Almos, Bognar Laszlo, Morrissy Sorana, Cavalli Florence, Taylor Michael D., van Sluis Peter, Koster Jan, Versteeg Rogier, Volckmann Richard, Mikkelsen Tom, Aldape Kenneth, Reifenberger Guido, Collins V. Peter, Majewski Jacek, Korshunov Andrey, Lichter Peter, Plass Christoph, Jabado Nada, Pfister Stefan M. Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma Cancer cell 2012;22 (4):425-437 [PubMed]
• Fieuw Annelies, Kumps Candy, Schramm Alexander, Pattyn Filip, Menten Björn, Antonacci Francesca, Sudmant Peter, Schulte Johannes H., van Roy N., Vergult Sarah, Buckley Patrick G., de Paepe A., Noguera Rosa, Versteeg Rogier, Stallings Raymond, Eggert Angelika, Vandesompele Jo, de Preter Katleen, Speleman Frank Identification of a novel recurrent 1q42.2-1qter deletion in high risk MYCN single copy 11q deleted neuroblastomas International journal of cancer. Journal international du cancer 2012;130 (11):2599-2606 [PubMed]
• Lamers Fieke, Schild Linda, Koster Jan, Speleman Frank, Øra Ingrid, Westerhout Ellen M., van Sluis Peter, Versteeg Rogier, Caron Huib N., Molenaar Jan J. Identification of BIRC6 as a novel intervention target for neuroblastoma therapy BMC cancer 2012;12 (1):285 [PubMed]
• Korshunov Andrey, Ryzhova Marina, Jones David T. W., Northcott Paul A., van Sluis Peter, Volckmann Richard, Koster Jan, Versteeg Rogier, Cowdrey Cynthia, Perry Arie, Picard Daniel, Rosenblum Marc, Giangaspero Felice, Aronica Eleonora, Schüller Ulrich, Hasselblatt Martin, Collins V. Peter, von Deimling Andreas, Lichter Peter, Huang Annie, Pfister Stefan M., Kool Marcel LIN28A immunoreactivity is a potent diagnostic marker of embryonal tumor with multilayered rosettes (ETMR) Acta neuropathologica 2012;124 (6):875-881 [PubMed]
• Molenaar Jan J., Domingo-Fernández Raquel, Ebus Marli E., Lindner Sven, Koster Jan, Drabek Ksenija, Mestdagh Pieter, van Sluis Peter, Valentijn Linda J., van Nes Johan, Broekmans Marloes, Haneveld Franciska, Volckmann Richard, Bray Isabella, Heukamp Lukas, Sprüssel Annika, Thor Theresa, Kieckbusch Kristina, Klein-Hitpass Ludger, Fischer Matthias, Vandesompele Jo, Schramm Alexander, van Noesel Max M., Varesio Luigi, Speleman Frank, Eggert Angelika, Stallings Raymond L., Caron Huib N., Versteeg Rogier, Schulte Johannes H. LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression Nature genetics 2012;44 (11):1199-1206 [PubMed]
• Stutterheim Janine, Ichou Fatima Ait, den Ouden Emmy, Versteeg Rogier, Caron Huib N., Tytgat Godelieve A. M., van der Schoot C. Ellen Methylated RASSF1a Is the First Specific DNA Marker for Minimal Residual Disease Testing in Neuroblastoma Clinical cancer research 2012;18 (3):808-814 [PubMed]
• Kemper Kristel, Versloot Miranda, Cameron Katherine, Colak Selçuk, de Sousa E Melo Felipe, de Jong Joan H., Bleackley Joanne, Vermeulen Louis, Versteeg Rogier, Koster Jan, Medema Jan Paul Mutations in the Ras-Raf Axis Underlie the Prognostic Value of CD133 in Colorectal Cancer Clinical cancer research 2012;18 (11):3132-3141 [PubMed]
• Lamers Sophia G. M. New therapeutic targets in the intrinsic apoptotic pathway in neuroblastoma 2012. 135p. ISBN 9789462030404. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Versteeg Rogier, Caron H. N.; Co-supervisor: Molenaar J. J.)
• Santo E. E., Ebus M. E., Koster J., Schulte J. H., Lakeman A., van Sluis P., Vermeulen J., Gisselsson D., Øra I., Lindner S., Buckley P. G., Stallings R. L., Vandesompele J., Eggert A., Caron H. N., Versteeg R., Molenaar J. J. Oncogenic activation of FOXR1 by 11q23 intrachromosomal deletion-fusions in neuroblastoma Oncogene 2012;31 (12):1571-1581 [PubMed]
• Bunt Jens, Hasselt Nancy E., Zwijnenburg Danny A., Hamdi Mohamed, Koster Jan, Versteeg Rogier, Kool Marcel OTX2 directly activates cell cycle genes and inhibits differentiation in medulloblastoma cells International journal of cancer. Journal international du cancer 2012;131 (2):E21-E32 [PubMed]
• Molenaar Jan J., Koster Jan, Zwijnenburg Danny A., van Sluis Peter, Valentijn Linda J., van der Ploeg Ida, Hamdi Mohamed, van Nes Johan, Westerman Bart A., van Arkel Jennemiek, Ebus Marli E., Haneveld Franciska, Lakeman Arjan, Schild Linda, Molenaar Piet, Stroeken Peter, van Noesel Max M., Ora Ingrid, Santo Evan E., Caron Huib N., Westerhout Ellen M., Versteeg Rogier Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes Nature 2012;483 (7391):589-U107 [PubMed]
• Stutterheim Janine, Zappeij-Kannegieter Lily, Ora Ingrid, van Sluis Peter G., Bras Johannes, den Ouden Emmy, Versteeg Rogier, Caron Huib N., van der Schoot C. Ellen, Tytgat Godelieve A. M. Stability of PCR Targets for Monitoring Minimal Residual Disease in Neuroblastoma Journal of molecular diagnostics 2012;14 (2):168-175 [PubMed]
• Lamers Fieke, Schild Linda, den Hartog Ilona J. M., Ebus Marli E., Westerhout Ellen M., Ora Ingrid, Koster Jan, Versteeg Rogier, Caron Huib N., Molenaar Jan J. Targeted BCL2 inhibition effectively inhibits neuroblastoma tumour growth European journal of cancer (Oxford, England 2012;48 (16):3093-3103 [PubMed]
• Lamers Fieke, Schild Linda, Koster Jan, Versteeg Rogier, Caron Huib N., Molenaar Jan J. Targeted BIRC5 silencing using YM155 causes cell death in neuroblastoma cells with low ABCB1 expression European journal of cancer (Oxford, England 2012;48 (5):763-771 [PubMed]
• Muñoz Javier, Stange Daniel E., Schepers Arnout G., van de Wetering Marc, Koo Bon-Kyoung, Itzkovitz Shalev, Volckmann Richard, Kung Kevin S., Koster Jan, Radulescu Sorina, Myant Kevin, Versteeg Rogier, Sansom Owen J., van Es Johan H., Barker Nick, van Oudenaarden Alexander, Mohammed Shabaz, Heck Albert J. R., Clevers Hans The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers EMBO journal 2012;31 (14):3079-3091 [PubMed]
• Bunt Jens The role of OTX2 in medulloblastoma 2012. 167p. ISBN 9789462031586. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Versteeg R.; Co-supervisor: Kool M.)

2011

• Teller Kathrin, Illner Doris, Thamm Stefanie, Casas-Delucchi Corella S., Versteeg Rogier, Indemans Mireille, Cremer Thomas, Cremer Marion A top-down analysis of Xa- and Xi-territories reveals differences of higher order structure at ≥ 20 Mb genomic length scales Nucleus (Austin, Tex.) 2011;2 (5):465-477 [PubMed]
• Murphy Derek M., Buckley Patrick G., Bryan Kenneth, Watters Karen M., Koster Jan, van Sluis Peter, Molenaar Jan, Versteeg Rogier, Stallings Raymond L. Dissection of the Oncogenic MYCN Transcriptional Network Reveals a Large Set of Clinically Relevant Cell Cycle Genes as Drivers of Neuroblastoma Tumorigenesis Molecular carcinogenesis 2011;50 (6):403-411 [PubMed]
• Buckley Patrick G., Das Sudipto, Bryan Kenneth, Watters Karen M., Alcock Leah, Koster Jan, Versteeg Rogier, Stallings Raymond L. Genome-wide DNA methylation analysis of neuroblastic tumors reveals clinically relevant epigenetic events and large-scale epigenomic alterations localized to telomeric regions International journal of cancer. Journal international du cancer 2011;128 (10):2296-2305 [PubMed]
• Bunt Jens, Hasselt Nancy E., Zwijnenburg Danny A., Koster Jan, Versteeg Rogier, Kool Marcel Joint binding of OTX2 and MYC in promotor regions is associated with high gene expression in medulloblastoma PLoS ONE 2011;6 (10):e26058 [PubMed]
• Lamers Fieke, van der Ploeg Ida, Schild Linda, Ebus Marli E., Koster Jan, Hansen Bo R., Koch Troels, Versteeg Rogier, Caron Huib N., Molenaar Jan J. Knockdown of survivin (BIRC5) causes apoptosis in neuroblastoma via mitotic catastrophe Endocrine-related cancer 2011;18 (6):657-668 [PubMed]
• de Sousa E Melo Felipe, Colak Selcuk, Buikhuisen Joyce, Koster Jan, Cameron Kate, de Jong Joan H., Tuynman Jurriaan B., Prasetyanti Pramudita R., Fessler Evelyn, van den Bergh Saskia P., Rodermond Hans, Dekker Evelien, van der Loos Chris M., Pals Steven T., van de Vijver Marc J., Versteeg Rogier, Richel Dick J., Vermeulen Louis, Medema Jan Paul Methylation of cancer-stem-cell-associated Wnt target genes predicts poor prognosis in colorectal cancer patients Cell stem cell 2011;9 (5):476-485 [PubMed]
• de Preter Katleen, Mestdagh Pieter, Vermeulen Joëlle, Zeka Fjoralba, Naranjo Arlene, Bray Isabella, Castel Victoria, Chen Caifu, Drozynska Elzbieta, Eggert Angelika, Hogarty Michael D., Izycka-Swieszewska Ewa, London Wendy B., Noguera Rosa, Piqueras Marta, Bryan Kenneth, Schowe Benjamin, van Sluis Peter, Molenaar Jan J., Schramm Alexander, Schulte Johannes H., Stallings Raymond L., Versteeg Rogier, Laureys Geneviève, van Roy Nadine, Speleman Frank, Vandesompele Jo miRNA expression profiling enables risk stratification in archived and fresh neuroblastoma tumor samples Clinical cancer research 2011;17 (24):7684-7692 [PubMed]
• Stutterheim J., Zappeij-Kannegieter L., Versteeg R., Caron H. N., van der Schoot C. E., Tytgat G. A. M. The prognostic value of fast molecular response of marrow disease in patients aged over 1 year with stage 4 neuroblastoma European journal of cancer (Oxford, England 2011;47 (8):1193-1202 [PubMed]

2010

• Fardin Paolo, Barla Annalisa, Mosci Sofia, Rosasco Lorenzo, Verri Alessandro, Versteeg Rogier, Caron Huib N., Molenaar Jan J., Ora Ingrid, Eva Alessandra, Puppo Maura, Varesio Luigi A biology-driven approach identifies the hypoxia gene signature as a predictor of the outcome of neuroblastoma patients Molecular cancer 2010;9 (1):185 [PubMed]
• Molenaar J. J., Ebus M. E., Koster J., Santo E., Geerts D., Versteeg R., Caron H. N. Cyclin D1 is a direct transcriptional target of GATA3 in neuroblastoma tumor cells Oncogene 2010;29 (18):2739-2745 [PubMed]
• Mokry Michal, Hatzis Pantelis, de Bruijn Ewart, Koster Jan, Versteeg Rogier, Schuijers Jurian, van de Wetering Marc, Guryev Victor, Clevers Hans, Cuppen Edwin Efficient Double Fragmentation ChIP-seq Provides Nucleotide Resolution Protein-DNA Binding Profiles PLoS ONE 2010;5 (11):e15092 [PubMed]
• Gierman H. J. Gene expression in chromosomal ridge domains. Influence on transcription, mRNA stability, codon usage, and evolution 2010. 168p. ISBN 9789090253053. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Versteeg R.)
• Revet Ingrid M. Homeobox genes in neuroblastoma 2010. 175p. ISBN 9789090253114. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Versteeg R.; Co-supervisor: Geerts D.)
• de Brouwer Sara, de Preter Katleen, Kumps Candy, Zabrocki Piotr, Porcu Michaël, Westerhout Ellen M., Lakeman Arjan, Vandesompele Jo, Hoebeeck Jasmien, van Maerken Tom, de Paepe Anne, Laureys Geneviève, Schulte Johannes H., Schramm Alexander, van den Broecke Caroline, Vermeulen Joëlle, van Roy Nadine, Beiske Klaus, Renard Marleen, Noguera Rosa, Delattre Olivier, Janoueix-Lerosey Isabelle, Kogner Per, Martinsson Tommy, Nakagawara Akira, Ohira Miki, Caron Huib N., Eggert Angelika, Cools Jan, Versteeg Rogier, Speleman Frank Meta-analysis of Neuroblastomas Reveals a Skewed ALK Mutation Spectrum in Tumors with MYCN Amplification Clinical cancer research 2010;16 (17):4353-4362 [PubMed]
• Revet Ingrid, Huizenga Gerda, Koster Jan, Volckmann Richard, van Sluis Peter, Versteeg Rogier, Geerts Dirk MSX1 induces the Wnt pathway antagonist genes DKK1, DKK2, DKK3, and SFRP1 in neuroblastoma cells, but does not block Wnt3 and Wnt5A signalling to DVL3 Cancer letters 2010;289 (2):195-207 [PubMed]
• Hölzel Michael, Huang Sidong, Koster Jan, Ora Ingrid, Lakeman Arjan, Caron Huib, Nijkamp Wouter, Xie Jing, Callens Tom, Asgharzadeh Shahab, Seeger Robert C., Messiaen Ludwine, Versteeg Rogier, Bernards René NF1 Is a Tumor Suppressor in Neuroblastoma that Determines Retinoic Acid Response and Disease Outcome Cell 2010;142 (2):218-229 [PubMed]
• Bunt Jens, de Haas Talitha G., Hasselt Nancy E., Zwijnenburg Danny A., Koster Jan, Versteeg Rogier, Kool Marcel Regulation of cell cycle genes and induction of senescence by overexpression of OTX2 in medulloblastoma cell lines Molecular cancer research 2010;8 (10):1344-1357 [PubMed]
• Schaaf Gerben, Hamdi Mohamed, Zwijnenburg Danny, Lakeman Arjan, Geerts Dirk, Versteeg Rogier, Kool Marcel Silencing of SPRY1 Triggers Complete Regression of Rhabdomyosarcoma Tumors Carrying a Mutated RAS Gene Cancer research 2010;70 (2):762-771 [PubMed]
• Verissimo Carla S., Molenaar Jan J., Meerman John, Puigvert Jordi Carreras, Lamers Fieke, Koster Jan, Danen Erik, van de Water Bob, Versteeg Rogier, Fitzsimons Carlos P., Vreugdenhil Erno Silencing of the microtubule-associated proteins doublecortin-like and doublecortin-like kinase-long induces apoptosis in neuroblastoma cells Endocrine-related cancer 2010;17 (2):399-414 [PubMed]
• Geerts Dirk, Koster Jan, Albert David, Koomoa Dana-Lynn T., Feith David J., Pegg Anthony E., Volckmann Richard, Caron Huib, Versteeg Rogier, Bachmann André S. The polyamine metabolism genes ornithine decarboxylase and antizyme 2 predict aggressive behavior in neuroblastomas with and without MYCN amplification International journal of cancer. Journal international du cancer 2010;126 (9):2012-2024 [PubMed]

2009

• Stutterheim Janine, Gerritsen Annemieke, Zappeij-Kannegieter Lily, Yalcin Bilgehan, dee Rob, van Noesel Max M., Berthold Frank, Versteeg Rogier, Caron Huib N., van der Schoot C. Ellen, Tytgat Godelieve A. M. Detecting Minimal Residual Disease in Neuroblastoma: The Superiority of a Panel of Real-Time Quantitative PCR Markers Clinical chemistry 2009;55 (7):1316-1326 [PubMed]
• Cimmino F., Schulte J. H., Zollo M., Koster J., Versteeg R., Iolascon A., Eggert A., Schramm A. Galectin-1 is a major effector of TrkB-mediated neuroblastoma aggressiveness Oncogene 2009;28 (19):2015-2023 [PubMed]
• Missiaglia Edoardo, Selfe Joanna, Hamdi Mohamed, Williamson Daniel, Schaaf Gerben, Fang Cheng, Koster Jan, Summersgill Brenda, Messahel Boo, Versteeg Rogier, Pritchard-Jones Kathy, Kool Marcel, Shipley Janet Genomic Imbalances in Rhabdomyosarcoma Cell Lines Affect Expression of Genes Frequently Altered in Primary Tumors: An Approach to Identify Candidate Genes Involved in Tumor Development Genes, chromosomes & cancer 2009;48 (6):455-467 [PubMed]
• Molenaar Jan J., Ebus Marli E., Geerts Dirk, Koster Jan, Lamers Fieke, Valentijn Linda J., Westerhout Ellen M., Versteeg Rogier, Caron Huib N. Inactivation of CDK2 is synthetically lethal to MYCN over-expressing cancer cells Proceedings of the National Academy of Sciences of the United States of America 2009;106 (31):12968-12973 [PubMed]
• Schulte Johannes H., Lim Soyoung, Schramm Alexander, Friedrichs Nicolaus, Koster Jan, Versteeg Rogier, Ora Ingrid, Pajtler Kristian, Klein-Hitpass Ludger, Kuhfittig-Kulle Steffi, Metzger Eric, Schüle Roland, Eggert Angelika, Buettner Reinhard, Kirfel Jutta Lysine-Specific Demethylase 1 Is Strongly Expressed in Poorly Differentiated Neuroblastoma: Implications for Therapy Cancer research 2009;69 (5):2065-2071 [PubMed]
• van Engelen Klaartje, Merks Johannes H. M., Lam Jan, Kremer Leontien C. M., Backes Manouk, Baars Marieke J. H., van der Pal Heleen J. H., Postma Alex V., Versteeg Rogier, Caron Huib N., Mulder Barbara J. M. Prevalence of congenital heart defects in neuroblastoma patients: a cohort study and systematic review of literature European journal of pediatrics 2009;168 (9):1081-1090 [PubMed]
• Molenaar Jan J. The cell cycle in neuroblastoma. From genomic aberrations to targeted intervention 2009. 132p. ISBN 9789090245003. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Caron H. N., Versteeg R.)
• van Hooff Sander R., Koster Jan, Hulsen Tim, van Schaik Barbera D. C., Roos Marco, van Batenburg Marcel F., Versteeg Rogier, van Kampen Antoine H. C. The Construction of Genome-Based Transcriptional Units Omics 2009;13 (2):105-114 [PubMed]
• Schulte Johannes H., Pentek Falk, Hartmann Wolfgang, Schramm Alexander, Friedrichs Nicolaus, Ora Ingrid, Koster Jan, Versteeg Rogier, Kirfel Jutta, Buettner Reinhard, Eggert Angelika The low-affinity neurotrophin receptor, p75, is upregulated in ganglioneuroblastoma/ganglioneuroma and reduces tumorigenicity of neuroblastoma cells in vivo International journal of cancer. Journal international du cancer 2009;124 (10):2488-2494 [PubMed]
• Huang Sidong, Laoukili Jamila, Epping Mirjam T., Koster Jan, Hölzel Michael, Westerman Bart A., Nijkamp Wouter, Hata Akiko, Asgharzadeh Shahab, Seeger Robert C., Versteeg Rogier, Beijersbergen Roderick L., Bernards René ZNF423 is critically required for retinoic acid-induced differentiation and is a marker of neuroblastoma outcome Cancer cell 2009;15 (4):328-340 [PubMed]

2008

• Molenaar Jan J., Ebus Marli E., Koster Jan, van Sluis Peter, van Noesel Carel J. M., Versteeg Rogier, Caron Huib N. Cyclin D1 and CDK4 activity contribute to the undifferentiated phenotype in neuroblastoma Cancer research 2008;68 (8):2599-2609 [PubMed]
• Koppen Arjen, Ait-Aissa Rachida, Koster Jan, Øra Ingrid, Bras Johannes, van Sluis Peter G., Caron Huib, Versteeg Rogier, Valentijn Linda J. Dickkopf-3 expression is a marker for neuroblastic tumor maturation and is down-regulated by MYCN International journal of cancer. Journal international du cancer 2008;122 (7):1455-1464 [PubMed]
• Koppen Arjen Gene regulation by MYCN in neuroblastoma 2008. 152p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Versteeg R.; Co-supervisor: Valentijn L. J.)
• Hatzis Pantelis, van der Flier Laurens G., van Driel Marc A., Guryev Victor, Nielsen Fiona, Denissov Sergei, Nijman Isaäc J., Koster Jan, Santo Evan E., Welboren Willem, Versteeg Rogier, Cuppen Edwin, van de Wetering Marc, Clevers Hans, Stunnenberg Hendrik G. Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells Molecular and cellular biology 2008;28 (8):2732-2744 [PubMed]
• Kool Marcel, Koster Jan, Bunt Jens, Hasselt Nancy E., Lakeman Arjan, van Sluis Peter, Troost Dirk, Schouten-van Meeteren Netteke A. Y., Caron Huib N., Cloos Jacqueline, Mrsić Alan, Ylstra Bauke, Grajkowska Wieslawa, Hartmann Wolfgang, Pietsch Torsten, Ellison David, Clifford Steven C., Versteeg Rogier Integrated Genomics Identifies Five Medulloblastoma Subtypes with Distinct Genetic Profiles, Pathway Signatures and Clinicopathological Features PLoS ONE 2008;3 (8):e3088 [PubMed]
• de Haas Talitha, Hasselt Nancy, Troost Dirk, Caron Huib, Popovic Mara, Zadravec-Zaletel Lorna, Grajkowska Wieslawa, Perek Marta, Osterheld Maria-Chiara, Ellison David, Baas Frank, Versteeg Rogier, Kool Marcel Molecular risk stratification of medulloblastoma patients based on immunohistochemical analysis of MYC, LDHB, and CCNB1 expression Clinical cancer research 2008;14 (13):4154-4160 [PubMed]
• Stutterheim Janine, Gerritsen Annemieke, Zappeij-Kannegieter Lily, Kleijn Ilona, dee Rob, Hooft Lotty, van Noesel Max M., Bierings Marc, Berthold Frank, Versteeg Rogier, Caron Huib N., van der Schoot C. Ellen, Tytgat Godelieve A. M. PHOX2B Is a Novel and Specific Marker for Minimal Residual Disease Testing in Neuroblastoma Journal of clinical oncology 2008;26 (33):5443-5449 [PubMed]
• Revet Ingrid, Huizenga Gerda, Chan Alvin, Koster Jan, Volckmann Richard, van Sluis Peter, Øra Ingrid, Versteeg Rogier, Geerts Dirk The MSX1 homeobox transcription factor is a downstream target of PHOX2B and activates the Delta-Notch pathway in neuroblastoma Experimental cell research 2008;314 (4):707-719 [PubMed]

2007

• Michels Evi, Vandesompele Jo, de Preter Katleen, Hoebeeck Jasmien, Vermeulen Joëlle, Schramm Alexander, Molenaar Jan J., Menten Björn, Marques Barbara, Stallings Raymond L., Combaret Valérie, Devalck Christine, de Paepe Anne, Versteeg Rogier, Eggert Angelika, Laureys Geneviève, van Roy Nadine, Speleman Frank ArrayCGH-based classification of neuroblastoma into genomic subgroups Genes, chromosomes & cancer 2007;46 (12):1098-1108 [PubMed]
• Zinner Roman, Teller Kathrin, Versteeg Rogier, Cremer Thomas, Cremer Marion Biochemistry meets nuclear architecture: multicolor immuno-FISH for co-localization analysis of chromosome segments and differentially expressed gene loci with various histone methylations Advances in enzyme regulation 2007;47:223-241 [PubMed]
• Henriksen Jorn R., Lokke Cecilie, Hammero Martin, Geerts Dirk, Versteeg Rogier, Flaegstad Trond, Einvik Christer Comparison of RNAi efficiency mediated by tetracycline-responsive H1 and U6 promoter variants in mammalian cell lines Nucleic acids research 2007;35 (9):e67 [PubMed]
• Koppen Arjen, Ait-Aissa Rachida, Hopman Saskia, Koster Jan, Haneveld Franciska, Versteeg Rogier, Valentijn Linda J. Dickkopf-1 is down-regulated by MYCN and inhibits neuroblastoma cell proliferation Cancer letters 2007;256 (2):218-228 [PubMed]
• Koppen Arjen, Ait-Aissa Rachida, Koster Jan, van Sluis Peter G., Ora Ingrid, Caron Huib N., Volckmann Richard, Versteeg Rogier, Valentijn Linda J. Direct regulation of the minichromosome maintenance complex by MYCN in neuroblastoma European journal of cancer (Oxford, England 2007;43 (16):2413-2422 [PubMed]
• Gierman Hinco J., Indemans Mireille H. G., Koster Jan, Goetze Sandra, Seppen Jurgen, Geerts Dirk, van Driel Roel, Versteeg Rogier Domain-wide regulation of gene expression in the human genome Genome research 2007;17 (9):1286-1295 [PubMed]
• Geerts Dirk, Wallick Christopher J., Koomoa Dana-Lynn T., Koster Jan, Versteeg Rogier, Go Ramon Christopher V., Bachmann André S. Expression of prenylated Rab acceptor 1 domain family, member 2 (PRAF2) in neuroblastoma: correlation with clinical features, cellular localization, and cerulenin-mediated apoptosis regulation Clinical cancer research 2007;13 (21):6312-6319 [PubMed]
• Goetze Sandra, Mateos-Langerak Julio, Gierman Hinco J., de Leeuw Wim, Giromus Osdilly, Indemans Mireille H. G., Koster Jan, Ondrej Vladan, Versteeg Rogier, van Driel Roel The three-dimensional structure of human interphase chromosomes is related to the transcriptome map Molecular and cellular biology 2007;27 (12):4475-4487 [PubMed]

2006

• de Haas Talitha, Oussoren Esmeralda, Grajkowska Wieslawa, Perek-Polnik Marta, Popovic Mara, Zadravec-Zaletel Lorna, Perera Marzia, Corte Giorgio, Wirths Oliver, van Sluis Peter, Pietsch Torsten, Troost Dirk, Baas Frank, Versteeg Rogier, Kool Marcel OTX1 and OTX2 expression correlates with the clinicopathologic classification of medulloblastomas Journal of neuropathology and experimental neurology 2006;65 (2):176-186 [PubMed]
• Valentijn Linda J., Koster Jan, Versteeg Rogier Read-through transcript from NM23-H1 into the neighboring NM23-H2 gene encodes a novel protein, NM23-LV Genomics 2006;87 (4):483-489 [PubMed]
• Kester Monique H. A., Kuiper George G. J. M., Versteeg Rogier, Visser Theo J. Regulation of type III iodothyronine deiodinase expression in human cell lines Endocrinology 2006;147 (12):5845-5854 [PubMed]

2005

• Hienonen T., Sammalkorpi H., Isohanni P., Versteeg R., Karikoski R., Aaltonen L. A. A 17p11.2 germline deletion in a patient with Smith-Magenis syndrome and neuroblastoma Journal of medical genetics 2005;42 (1):e3 [PubMed]
• van Noesel M. M. Aberrant DNA hypermethylation and apoptotic defects in pediatric neuroblatomas 2005. 115p. ISBN 9789090190266. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Versteeg R., Voute P. A.)
• Schramm Alexander, Schulte Johannes H., Astrahantseff Kathy, Apostolov Ognjan, Limpt Vera van, Sieverts Hauke, Kuhfittig-Kulle Steffi, Pfeiffer Petra, Versteeg Rogier, Eggert Angelika Biological effects of TrkA and TrkB receptor signaling in neuroblastoma Cancer letters 2005;228 (1-2):143-153 [PubMed]
• Gierman Hinco J., Versteeg Rogier Clustering of highly expressed genes in the human genome.in: N. N., editors. Encyclopedia of life sciences (eLS). Chichester: John Wiley & Sons Ltd; 2005. p. 1-4
• Mathay K. K., Reynolds C. P., Versteeg R. High-risk neuroblastoma: beyond intensification to novel therapyin: M. C. Perry, editors. American society of clinical oncology educational book. S.l.: ASCO 2005; 2005. p. 786-797
• Valentijn Linda J., Koppen Arjen, van Asperen Ronald, Root Heather A., Haneveld Franciska, Versteeg Rogier Inhibition of a new differentiation pathway in neuroblastoma by copy number defects of N-myc, Cdc42, and nm23 genes Cancer research 2005;65 (8):3136-3145 [PubMed]
• Geerts Dirk, Revet Ingrid, Jorritsma Gerda, Schilderink Nathalie, Versteeg Rogier MEIS homeobox genes in neuroblastoma Cancer letters 2005;228 (1-2):43-50 [PubMed]
• Versteeg R. Molecular biology of childhood tumoursin: P. A. Voûte, A. Barrett, M. Stevens, H. Caron, editors. Cancer in children-clinical management. 5th edition. Oxford: Oxford University Press; 2005.
• van Limpt V. A. M. E. Neuroblastoma, developmental control genes and cell fates decisions in the sympathetic nervous system 2005. 155p. ISBN 9789090188782. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Versteeg R.)
• van Limpt Vera, Chan Alvin, Schramm Alexander, Eggert Angelika, Versteeg Rogier Phox2B mutations and the Delta-Notch pathway in neuroblastoma Cancer letters 2005;228 (1-2):59-63 [PubMed]

2004

• van Noesel Max M., Versteeg Rogier Pediatric neuroblastomas: genetic and epigenetic 'Danse Macabre' Gene 2004;325:1-15 [PubMed]
• van Limpt Vera, Schramm Alexander, van Lakeman Arjan, Sluis Peter, Chan Alvin, van Noesel Max, Baas Frank, Caron Huib, Eggert Angelika, Versteeg Rogier The Phox2B homeobox gene is mutated in sporadic neuroblastomas Oncogene 2004;23 (57):9280-9288 [PubMed]

2003

• van Noesel Max M., van Bezouw Saskia, Voûte P. A., Herman James G., Pieters Rob, Versteeg Rogier Clustering of hypermethylated genes in neuroblastoma Genes, chromosomes & cancer 2003;38 (3):226-233 [PubMed]
• van Kampen A. H. C., Ruijter J. M., van Schaik B. D. C., Caron H. N., Versteeg R. Gene expression informatics and analysisin: M. R. Barnes, I. C. Gray, editors. Bioinformatics for geneticists. Chichester: John Wiley & Sons; 2003. p. 319-344, ISBN 9780470843932
• van Limpt Vera A. E., Chan Alvin J., van Sluis Peter G., Caron Huib N., van Noesel Carel J. M., Versteeg Rogier High delta-like 1 expression in a subset of neuroblastoma cell lines corresponds to a differentiated chromaffin cell type International journal of cancer. Journal international du cancer 2003;105 (1):61-69 [PubMed]
• Molenaar Jan J., van Sluis Peter, Boon Kathy, Versteeg Rogier, Caron Huib N. Rearrangements and increased expression of cyclin D1 (CCND1) in neuroblastoma Genes, chromosomes & cancer 2003;36 (3):242-249 [PubMed]
• Godfried M. B. Role of nm23 in neuroblastoma. From genetic aberrations to pathways abnormalities 2003. 114p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Caron H. N.; Co-supervisor: Versteeg R.)
• Versteeg Rogier, van Schaik Barbera D. C., van Batenburg Marinus F., Roos Marco, Monajemi Ramin, Caron Huib, Bussemaker Harmen J., van Kampen Antoine H. C. The human transcriptome map reveals extremes in gene density, intron length, GC content, and repeat pattern for domains of highly and weakly expressed genes Genome research 2003;13 (9):1998-2004 [PubMed]
• van Noesel Max M., Pieters Rob, Voûte P. A., Versteeg Rogier The N-myc paradox: N-myc overexpression in neuroblastomas is associated with sensitivity as well as resistance to apoptosis Cancer letters 2003;197 (1-2):165-172 [PubMed]
• Geerts Dirk, Schilderink Nathalie, Jorritsma Gerda, Versteeg Rogier The role of the MEIS homeobox genes in neuroblastoma Cancer letters 2003;197 (1-2):87-92 [PubMed]

2002

• Godfried M. B., Veenstra M., Valent A., Sluis P. v, Voûte P. A., Versteeg R., Caron H. N. Lack of interstitial chromosome 1p deletions in clinically-detected neuroblastoma European journal of cancer (Oxford, England 2002;38 (11):1513-1519 [PubMed]
• van Roy Nadine, Vandesompele Jo, Berx Geert, Staes Katrien, van Gele Mireille, de Smet Els, de Paepe Anne, Laureys Geneviève, van der Drift Pauline, Versteeg Rogier, van Roy Frans, Speleman Frank Localization of the 17q breakpoint of a constitutional 1;17 translocation in a patient with neuroblastoma within a 25-kb segment located between the ACCN1 and TLK2 genes and near the distal breakpoints of two microdeletions in neurofibromatosis type 1 patients Genes, chromosomes & cancer 2002;35 (2):113-120 [PubMed]
• Godfried Marc B., Veenstra Monique, van Sluis Peter, Boon Kathy, van Asperen Ronald, Hermus Marie Christien, van Schaik Barbara D. C., Voûte Tom P. A., Schwab Manfred, Versteeg Rogier, Caron Huib N. The N-myc and c-myc downstream pathways include the chromosome 17q genes nm23-H1 and nm23-H2 Oncogene 2002;21 (13):2097-2101 [PubMed]
• van Noesel Max M., van Bezouw Saskia, Salomons Gajja S., Voûte P. A., Pieters Rob, Baylin Steve B., Herman James G., Versteeg Rogier Tumor-specific down-regulation of the tumor necrosis factor-related apoptosis-inducing ligand decoy receptors DcR1 and DcR2 is associated with dense promoter hypermethylation Cancer research 2002;62 (7):2157-2161 [PubMed]

2001

• Caron H., Spieker N., Godfried M., Veenstra M., van Sluis P., de Kraker J., Voûte P., Versteeg R. Chromosome bands 1p35-36 contain two distinct neuroblastoma tumor suppressor loci, one of which is imprinted Genes, chromosomes & cancer 2001;30 (2):168-174 [PubMed]
• Boon K., Caron H. N., van Asperen R., Valentijn L., Hermus M. C., van Sluis P., Roobeek I., Weis I., Voûte P. A., Schwab M., Versteeg R. N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis EMBO journal 2001;20 (6):1383-1393 [PubMed]
• Caron H., van Schaik B., van der Mee M., Baas F., Riggins G., van Sluis P., Hermus M. C., van Asperen R., Boon K., Voûte P. A., Heisterkamp S., van Kampen Antoine, Versteeg R. The human transcriptome map: clustering of highly expressed genes in chromosomal domains Science 2001;291 (5507):1289-1292 [PubMed]
• Spieker N., van Sluis P., Beitsma M., Boon K., van Schaik B. D., van Kampen A. H., Caron H., Versteeg R. The MEIS1 oncogene is highly expressed in neuroblastoma and amplified in cell line IMR32 Genomics 2001;71 (2):214-221 [PubMed]
• Spieker N., Beitsma M., van Sluis P., Chan A., Caron H., Versteeg R. Three chromosomal rearrangements in neuroblastoma cluster within a 300-kb region on 1p36.1 Genes, chromosomes & cancer 2001;31 (2):172-181 [PubMed]

2000

• Spieker N., Beitsma M., van Sluis P., Roobeek I., den Dunnen J. T., Speleman F., Caron H., Versteeg R. An integrated 5-Mb physical, genetic, and radiation hybrid map of a 1p36.1 region implicated in neuroblastoma pathogenesis Genes, chromosomes & cancer 2000;27 (2):143-152 [PubMed]
• van Limpt V., Chan A., Caron H., Sluis P. V., Boon K., Hermus M. C., Versteeg R. SAGE analysis of neuroblastoma reveals a high expression of the human homologue of the Drosophila Delta gene Medical and pediatric oncology 2000;35 (6):554-558 [PubMed]
• van Kampen A. H., van Schaik B. D., Pauws E., Michiels E. M., Ruijter J. M., Caron H. N., Versteeg R., Heisterkamp S. H., Leunissen J. A., Baas F., van der Mee M. USAGE: a web-based approach towards the analysis of SAGE data. Serial Analysis of Gene Expression Bioinformatics (Oxford, England) 2000;16 (10):899-905 [PubMed]

1999

• van der Drift P., Chan A., Zehetner G., Westerveld A., Versteeg R. Multiple MSP pseudogenes in a local repeat cluster on 1p36.2: An expanding genomic graveyard? Genomics 1999;62 (1):74-81 [PubMed]
• Wuyts W., Spieker N., van Roy N., de Boulle K., de Paepe A., Willems P. J., van Hul W., Versteeg R., Speleman F. Refined physical mapping and genomic structure of the EXTL1 gene Cytogenetics and cell genetics 1999;86 (3-4):267-270 [PubMed]

1998

• van Gele M., van Roy N., Ronan S. G., Messiaen L., Vandesompele J., Geerts M. L., Naeyaert J. M., Blennow E., Bar-Am I., Das Gupta T. K., van der Drift P., Versteeg R., Leonard J. H., Speleman F. Molecular analysis of 1p36 breakpoints in two Merkel cell carcinomas Genes, chromosomes & cancer 1998;23 (1):67-71 [PubMed]

1997

• Versteeg R. Aberrant methylation in cancer American journal of human genetics 1997;60 (4):751-754 [PubMed]
• van Roy N., Laureys G., van Gele M., Opdenakker G., Miura R., van der Drift P., Chan A., Versteeg R., Speleman F. Analysis of 1;17 translocation breakpoints in neuroblastoma: implications for mapping of neuroblastoma genes European journal of cancer (Oxford, England 1997;33 (12):1974-1978 [PubMed]
• van Roy N., Jauch A., van Gele M., Laureys G., Versteeg R., de Paepe A., Cremer T., Speleman F. Comparative genomic hybridization analysis of human neuroblastomas: detection of distal 1p deletions and further molecular genetic characterization of neuroblastoma cell lines Cancer genetics and cytogenetics 1997;97 (2):135-142 [PubMed]
• van Gele M., van Roy N., Jauch A., Laureys G., Benoit Y., Schelfhout V., de Potter C. R., Brock P., Uyttebroeck A., Sciot R., Schuuring E., Versteeg R., Speleman F. Sensitive and reliable detection of genomic imbalances in human neuroblastomas using comparative genomic hybridisation analysis European journal of cancer (Oxford, England 1997;33 (12):1979-1982 [PubMed]

1996

• Cheng N. C., Chan A. J., Beitsma M. M., Speleman F., Westerveld A., Versteeg R. A human modifier of methylation for class I HLA genes (MEMO-1) maps to chromosomal bands 1p35-36.1 Human molecular genetics 1996;5 (3):309-317 [PubMed]
• Caron H., van Sluis P., de Kraker J., Bökkerink J., Egeler M., Laureys G., Slater R., Westerveld A., Voûte P. A., Versteeg R. Allelic loss of chromosome 1p as a predictor of unfavorable outcome in patients with neuroblastoma New England journal of medicine 1996;334 (4):225-230 [PubMed]
• Caron H. N., Voute P. A., Versteeg R. Allelic loss of chromosome 1p in neuroblastoma - Reply New England journal of medicine 1996;334 (24):1609
• Caron H., van Sluis P., Buschman R., Pereira do Tanque R., Maes P., Beks L., de Kraker J., Voûte P. A., Vergnaud G., Westerveld A., Slater R., Versteeg R. Allelic loss of the short arm of chromosome 4 in neuroblastoma suggests a novel tumour suppressor gene locus Human genetics 1996;97 (6):834-837 [PubMed]
• Paul D. R., Gawlik C., Versteeg R., Arps H., Kleeberg U. R. Correlation between the expression of Ki67 and HLA-DR antigens in fotemustine-treated melanoma cell lines Onkologie 1996;19 (4):334-336
• Cheng N. C., Beitsma M., Chan A., Op den Camp I., Westerveld A., Pronk J., Versteeg R. Lack of class I HLA expression in neuroblastoma is associated with high N-myc expression and hypomethylation due to loss of the MEMO-1 locus Oncogene 1996;13 (8):1737-1744 [PubMed]
• Hofstra R. M., Cheng N. C., Hansen C., Stulp R. P., Stelwagen T., Clausen N., Tommerup N., Caron H., Westerveld A., Versteeg R., Buys C. H. No mutations found by RET mutation scanning in sporadic and hereditary neuroblastoma Human genetics 1996;97 (3):362-364 [PubMed]

1995

• Versteeg R., Caron H., Cheng N. C., van der Drift P., Slater R., Westerveld A., Voûte P. A., Delattre O., Laureys G., van Roy N. 1p36: every subband a suppressor? European journal of cancer (Oxford, England 1995;31A (4):538-541 [PubMed]
• van der Drift P., Chan A., Laureys G., van Roy N., Sickmann G., den Dunnen J. T., Westerveld A., Speleman F., Versteeg R. Balanced translocation in a neuroblastoma patient disrupts a cluster of small nuclear RNA U1 and tRNA genes in chromosomal band 1p36 Genes, chromosomes & cancer 1995;14 (1):35-42 [PubMed]
• Laureys G., Versteeg R., Speleman F., van der Drift P., Francke U., Opdenakker G., van Roy N. Characterisation of the chromosome breakpoints in a patient with a constitutional translocation t(1;17)(p36.31-p36.13;q11.2-q12) and neuroblastoma European journal of cancer (Oxford, England 1995;31A (4):523-526 [PubMed]
• Laureys G., Speleman F., Versteeg R., van der Drift P., Chan A., Leroy J., Francke U., Opdenakker G., van Roy N. Constitutional translocation t(1;17)(p36.31-p36.13;q11.2-q12.1) in a neuroblastoma patient. Establishment of somatic cell hybrids and identification of PND/A12M2 on chromosome 1 and NF1/SCYA7 on chromosome 17 as breakpoint flanking single copy markers Oncogene 1995;10 (6):1087-1093 [PubMed]
• Cheng N. C., van Roy N., Chan A., Beitsma M., Westerveld A., Speleman F., Versteeg R. Deletion mapping in neuroblastoma cell lines suggests two distinct tumor suppressor genes in the 1p35-36 region, only one of which is associated with N-myc amplification Oncogene 1995;10 (2):291-297 [PubMed]
• Caron H., Peter M., van Sluis P., Speleman F., de Kraker J., Laureys G., Michon J., Brugières L., Voûte P. A., Westerveld A., Slater R., Delattre O., Versteeg R. EVIDENCE FOR 2 TUMOR-SUPPRESSOR LOCI ON CHROMOSOMAL BANDS-1P35-36 INVOLVED IN NEUROBLASTOMA - ONE PROBABLY IMPRINTED, ANOTHER ASSOCIATED WITH N-MYC AMPLIFICATION Human molecular genetics 1995;4 (4):535-539 [PubMed]
• van Roy N., Forus A., Myklebost O., Cheng N. C., Versteeg R., Speleman F. Identification of two distinct chromosome 12-derived amplification units in neuroblastoma cell line NGP Cancer genetics and cytogenetics 1995;82 (2):151-154 [PubMed]
• van Roy N., Cheng N. C., Laureys G., Opdenakker G., Versteeg R., Speleman F. Molecular cytogenetic analysis of 1;17 translocations in neuroblastoma European journal of cancer (Oxford, England 1995;31A (4):530-535 [PubMed]

1994

• van Roy N., Laureys G., Cheng N. C., Willem P., Opdenakker G., Versteeg R., Speleman F. 1;17 translocations and other chromosome 17 rearrangements in human primary neuroblastoma tumors and cell lines Genes, chromosomes & cancer 1994;10 (2):103-114 [PubMed]
• van der Drift P., Chan A., van Roy N., Laureys G., Westerveld A., Speleman F., Versteeg R. A multimegabase cluster of snRNA and tRNA genes on chromosome 1p36 harbours an adenovirus/SV40 hybrid virus integration site Human molecular genetics 1994;3 (12):2131-2136 [PubMed]
• Caron H., van Sluis P., van Roy N., de Kraker J., Speleman F., Voûte P. A., Westerveld A., Slater R., Versteeg R. Recurrent 1;17 translocations in human neuroblastoma reveal nonhomologous mitotic recombination during the S/G2 phase as a novel mechanism for loss of heterozygosity American journal of human genetics 1994;55 (2):341-347 [PubMed]

1993

• Caron H., van Sluis P., van Hoeve M., de Kraker J., Bras J., Slater R., Mannens M., Voûte P. A., Westerveld A., Versteeg R. Allelic loss of chromosome 1p36 in neuroblastoma is of preferential maternal origin and correlates with N-myc amplification Nature genetics 1993;4 (2):187-190 [PubMed]
• Caron H., van Sluis P., van Hoeve M., de Kraker J., Bras J., Slater R., Mannens M., Voûte P. A., Westerveld A., Versteeg R. Allelic loss of chromosome 1p36 in neuroblastoma is of preferential maternal origin and correlates with N-myc amplification [Correction] Nature genetics 1993;4 (4):431-431
• van Roy N., Laureys G., Versteeg R., Opdenakker G., Speleman F. High-resolution fluorescence mapping of 46 DNA markers to the short arm of human chromosome 1 Genomics 1993;18 (1):71-78 [PubMed]

1992

• Versteeg R. CORRECTION Immunology today 1992;13 (10):426
• Boschman G. A., Rens W., Manders E. M., Slater R. M., Versteeg R., Aten J. A. Detection of recurrent chromosome abnormalities in Ewing's sarcoma and peripheral neuroectodermal tumor cells using bivariate flow karyotyping Genes, chromosomes & cancer 1992;5 (4):375-384 [PubMed]
• Versteeg R. NK cells and T cells: mirror images? Immunology today 1992;13 (7):244-247 [PubMed]

1989

• Versteeg R., Peltenburg L. T., Plomp A. C., Schrier P. I. High expression of the c-myc oncogene renders melanoma cells prone to lysis by natural killer cells Journal of immunology (Baltimore, Md. 1989;143 (12):4331-4337 [PubMed]
• van 't Veer L. J., Burgering B. M., Versteeg R., Boot A. J., Ruiter D. J., Osanto S., Schrier P. I., Bos J. L. N-ras mutations in human cutaneous melanoma from sun-exposed body sites Molecular and cellular biology 1989;9 (7):3114-3116 [PubMed]
• Versteeg R., Krüse-Wolters K. M., Plomp A. C., van Leeuwen A., Stam N. J., Ploegh H. L., Ruiter D. J., Schrier P. I. Suppression of class I human histocompatibility leukocyte antigen by c-myc is locus specific Journal of experimental medicine 1989;170 (3):621-635 [PubMed]

1988

• Versteeg R., NOORDERMEER I. A., Krüse-Wolters M., Ruiter D. J., Schrier P. I. c-myc down-regulates class I HLA expression in human melanomas EMBO journal 1988;7 (4):1023-1029 [PubMed]

1984

• KONINGS A., HUPKES P., Versteeg R., Grosveld G., Reuser A., Galjaard H. Cloning a cDNA for the lysosomal alpha-glucosidase Biochemical and biophysical research communications 1984;119 (1):252-258 [PubMed]

1983

• van der Avoort H. G., Teertstra R., Versteeg R., Weisbeek P. J. GENES AND REGULATORY SEQUENCES OF BACTERIOPHAGE-PHI-X174 BIOCHIMICA ET BIOPHYSICA ACTA 1983;741 (1):94-102 [PubMed]