Prof. T.B.H. Geijtenbeek PhD publications

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Publications Prof. PhD T.B.H. Geijtenbeek

Position
Full Professor
Main activities
Research, Other
Specialisation
Immunology
Focus of research

We investigate  how pathogens and in particular viruses (HIV-1, SARS-CoV-2, Zika and Dengue virus) infect humans. We thereby study mucosal dendritic cells that function as sentinels that sense invading pathogens and induce appropriate immune responses. However, specific viruses hijack the dendritic cells to establish dissemination throughout the body. Thus, dendritic cells are important in determining the susceptibility of humans to viruses such as HIV-1 and SARS-CoV-2. We use primary human dendritic cells isolated from skin and mucosal tissues and we have also developed different ex vivo human tissue infection models to investigate virus susceptibility in a physiological relevant model. We aim to identify the molecular mechanisms triggered by the pathogens to infiltrate the body via dendritic cells and this will provide novel targets to counteract infections or induce specific immune responses.

2021

  • van der Donk Lieve E. H., Ates Louis S., van der Spek Jet, Tukker Laura M., Geijtenbeek Teunis B. H., van Heijst Jeroen W. J. Separate signaling events control TCR downregulation and T cell activation in primary human T cells Immunity Inflammation and Disease 2021;9 (1):223-238 [PubMed]

2020

  • Mason Lauren M. K., Koetsveld Joris, Trentelman Jos J. A., Kaptein Tanja M., Hoornstra Dieuwertje, Wagemakers Alex, Fikrig Michelle M., Ersoz Jasmin I., Oei Anneke, Geijtenbeek Teunis B. H., Hovius Joppe W. R. Borrelia miyamotoi Activates Human Dendritic Cells and Elicits T Cell Responses Journal of immunology (Baltimore, Md. 2020;204 (2):386-393 [PubMed]
  • Nijmeijer Bernadien M. Dissemination of HIV-1 and HCV is directed by Langerhans cells: Interplay between receptors 2020. 187p. ISBN 9789493197121. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Geijtenbeek Teunis B. H.; Co-supervisor: Ribeiro Carla M. S.)
  • Hoornenborg Elske, Coyer Liza, Boyd Anders, Achterbergh Roel Christiaan Alfons, Schim van der Loeff Maarten Franciscus, Bruisten Sylvia, de Vries Henry John Christiaan, Koopsen Jelle, van de Laar Thijs J. W., Prins Maria, van Bergen J. E. A. M., de Bree G. J., Brokx P., Deug F., Heidenrijk M., Prins M., Reiss P., van der Valk M., Davidovich U., Geerlings S. E., Hoornenborg E., Oomen A., Sighem A. van, Zuilhof W., Bruinderink M. L. Groot, Achterbergh R. C. A., van Agtmael M., Ananworanich J., van de Beek D., van den Berk G. E. L., Bezemer D., van Bijnen A., Dijkstra M., Geijtenbeek T. B. H., Godfried M. H., Goorhuis A., Hankins C. A., Hogewoning A., Hovius J. W., Kootstra N. A., Lauw F., van der Meer J. T., Mulder B. J., Nellen F. J., van der Poll T., van Rooijen M. S., Sonder G. J., de Vries H. J., Wiersinga W. J., Wit F. W. High incidence of HCV in HIV-negative men who have sex with men using pre-exposure prophylaxis Journal of hepatology 2020;72 (5):855-864 [PubMed]
  • Stunnenberg Melissa, van Pul Lisa, Sprokholt Joris K., van Dort Karel A., Gringhuis Sonja I., Geijtenbeek Teunis B. H., Kootstra Neeltje A. MAVS genetic variation is associated with decreased HIV-1 replication in vitro and reduced cd4+ t cell infection in HIV-1-infected individuals Viruses 2020;12 (7) [PubMed]
  • Laksono Brigitta M., Fortugno Paola, Nijmeijer Bernadien M., de Vries Rory D., Cordisco Sonia, Kuiken Thijs, Geijtenbeek Teunis B. H., Duprex W. Paul, Brancati Francesco, de Swart Rik L. Measles skin rash: Infection of lymphoid and myeloid cells in the dermis precedes viral dissemination to the epidermis PLoS pathogens 2020;16 (10) [PubMed]
  • Nijmeijer Bernadien M., Langedijk Catharina J. M., Geijtenbeek Teunis B. H. Mucosal Dendritic Cell Subsets Control HIV-1's Viral Fitness Annual review of virology 2020;7 (1):385-402 [PubMed]
  • Bermejo-Jambrina Marta, Eder Julia, Kaptein Tanja M., Helgers Leanne C., Brouwer Philip J.M., van Hamme John L., Vlaar Alexander P.J., van Baarle Frank E.H.P., de Bree Godelieve J., Nijmeijer Bernadien M., Koostra Neeltje A., van Gils Marit J., Sanders Rogier W., Geijtenbeek Teunis B. H. SARS-CoV-2 Infection and Transmission Depends on Heparan Sulfates and Is Blocked by Low Molecular Weight Heparins bioRxiv 2020
  • Nijmeijer Bernadien M., Eder Julia, Langedijk Catharina J. M., Kaptein Tanja M., Meeussen Sofie, Zimmermann Pascale, Ribeiro Carla M. S., Geijtenbeek Teunis B. H. Syndecan 4 Upregulation on Activated Langerhans Cells Counteracts Langerin Restriction to Facilitate Hepatitis C Virus Transmission Frontiers in immunology 2020;11 [PubMed]
  • Stunnenberg Melissa, Sprokholt Joris K., van Hamme John L., Kaptein Tanja M., Zijlstra-Willems Esther M., Gringhuis Sonja I., Geijtenbeek Teunis B. H. Synthetic Abortive HIV-1 RNAs Induce Potent Antiviral Immunity Frontiers in immunology 2020;11 [PubMed]
  • van Teijlingen Nienke H., Helgers Leanne C., Zijlstra - Willems Esther M., van Hamme John L., Ribeiro Carla M. S., Strijbis Karin, Geijtenbeek Teunis B. H. Vaginal dysbiosis associated-bacteria Megasphaera elsdenii and Prevotella timonensis induce immune activation via dendritic cells Journal of reproductive immunology 2020;138 [PubMed]
  • Busold Stefanie, Nagy Noémi A., Tas Sander W., van Ree Ronald, de Jong Esther C., Geijtenbeek Teunis B. H. Various Tastes of Sugar: The Potential of Glycosylation in Targeting and Modulating Human Immunity via C-Type Lectin Receptors Frontiers in immunology 2020;11 [PubMed]

2019

  • Mason Lauren M. K. Beyond skin deep: Exploring interactions between Borrelia and the host immune system 2019. 169p. ISBN 9789463612951. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Hovius J. W. R. , Geijtenbeek T. B. H.)
  • Sprokholt Joris K. Dengue virus infection of dendritic cells: Sensing viral replication during inflammation and immunity 2019. 191p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Geijtenbeek T. B. H.; Co-supervisor: Gringhuis S. I.)
  • Nijmeijer Bernadien M, Sarrami-Forooshani Ramin, Steba Gaby S, Schreurs Renée Rce, Koekkoek Sylvie M, Molenkamp Richard, Schinkel Janke, Reiss Peter, Siegenbeek van Heukelom Matthijs L, van der Valk Marc, Ribeiro Carla Ms, Geijtenbeek Teunis Bh HIV-1 exposure and immune activation enhance sexual transmission of Hepatitis C virus by primary Langerhans cells Journal of the International AIDS Society 2019;22 (3):e25268 [PubMed]
  • Schreurs Renée R. C. E., Baumdick Martin E., Sagebiel Adrian F., Kaufmann Max, Mokry Michal, Klarenbeek Paul L., Schaltenberg Nicola, Steinert Fenja L., van Rijn Jorik M., Drewniak Agata, The Sarah-May M. L., Bakx Roel, Derikx Joep P. M., de Vries Niek, Corpeleijn Willemijn E., Pals Steven T., Gagliani Nicola, Friese Manuel A., Middendorp Sabine, Nieuwenhuis Edward E. S., Reinshagen Konrad, Geijtenbeek Teunis B. H., van Goudoever Johannes B., Bunders Madeleine J. Human Fetal TNF-α-Cytokine-Producing CD4 + Effector Memory T Cells Promote Intestinal Development and Mediate Inflammation Early in Life Immunity 2019;50 (2):462-476.e8 [PubMed]
  • van Dalen Rob, Diaz Jacinto S. de la Cruz, Rumpret Matevž, Fuchsberger Felix F., van Teijlingen Nienke H., Hanske Jonas, Rademacher Christoph, Geijtenbeek Teunis B. H., van Strijp Jos A. G., Weidenmaier Christopher, Peschel Andreas, Kaplan Daniel H., van Sorge Nina M. Langerhans cells sense Staphylococcus aureus wall teichoic acid through langerin to induce inflammatory responses mBio 2019;10 (3) [PubMed]
  • Nijmeijer Bernadien M., Geijtenbeek Teunis B. H. Negative and positive selection pressure during sexual transmission of transmitted founder HIV-1 Frontiers in immunology 2019;10 (JULY) [PubMed]
  • Hertoghs Nina, Nijmeijer Bernadien M., van Teijlingen Nienke H., Fenton-May Angharad E., Kaptein Tanja M., van Hamme John L., Kappes John C., Kootstra Neeltje A., Hahn Beatrice H., Borrow Persephone, Ribeiro Carla M. S., Geijtenbeek Teunis B. H. Sexually transmitted founder HIV-1 viruses are relatively resistant to Langerhans cell-mediated restriction PLoS ONE 2019;14 (12) [PubMed]
  • Nijmeijer Bernadien M., Koopsen Jelle, Schinkel Janke, Prins Maria, Geijtenbeek Teunis B. H. Sexually transmitted hepatitis C virus infections: current trends, and recent advances in understanding the spread in men who have sex with men Journal of the International AIDS Society 2019;22 (S6) [PubMed]

2018

  • Bermejo-Jambrina Marta, Eder Julia, Helgers Leanne C., Hertoghs Nina, Nijmeijer Bernadien M., Stunnenberg Melissa, Geijtenbeek Teunis B. H. C-type lectin receptors in antiviral immunity and viral escape Frontiers in immunology 2018;9 (MAR) [PubMed]
  • Stunnenberg Melissa, Geijtenbeek Teunis B. H., Gringhuis Sonja I. DDX3 in HIV-1 infection and sensing: A paradox Cytokine & growth factor reviews 2018;40:32-39 [PubMed]
  • Hähnlein Janine S., Ramwadhdoebe Tamara H., Semmelink Johanna F., Choi Ivy Y., Berger Ferco H., Maas Mario, Gerlag Danielle M., Tak Paul P., Geijtenbeek Teunis B. H., van Baarsen Lisa G. M. Distinctive expression of T cell guiding molecules in human autoimmune lymph node stromal cells upon TLR3 triggering Scientific reports 2018;8 (1):1736 [PubMed]
  • Hähnlein Janine S. Human lymph node stromal cells and their role in rheumatoid arthritis 2018. 196p. ISBN 9789463752060. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Tak P. P. , Geijtenbeek T. B. H.; Co-supervisor: van Baarsen E. G. M.)
  • Hähnlein Janine S., Nadafi Reza, de Jong Tineke, Ramwadhdoebe Tamara H., Semmelink Johanna F., Maijer Karen I., Zijlstra Ijsbrand A., Maas Mario, Gerlag Danielle M., Geijtenbeek Teunis B. H., Tak Paul P., Mebius Reina E., van Baarsen Lisa G. M. Impaired lymph node stromal cell function during the earliest phases of rheumatoid arthritis Arthritis research & therapy 2018;20 (1):35 [PubMed]
  • Sprokholt Joris, Helgers Leanne C., Geijtenbeek Teunis B. H. Innate immune receptors drive dengue virus immune activation and disease Future Virology 2018;13 (4):287-305 [PubMed]
  • Hertoghs Nina Molecular mechanisms controlling dendritic cell functions in HIV-1 and Ebolavirus infection 2018. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Geijtenbeek T. B. H.; Co-supervisor: Gringhuis S. I.)

2017

  • Rodríguez-Carrio Javier, Hähnlein Janine S., Ramwadhdoebe Tamara H., Semmelink Johanna F., Choi Ivy Y., van Lienden Krijn P., Maas Mario, Gerlag Danielle M., Tak Paul P., Geijtenbeek Teunis B. H., van Baarsen Lisa G. M. Brief Report: Altered Innate Lymphoid Cell Subsets in Human Lymph Node Biopsy Specimens Obtained During the At-Risk and Earliest Phases of Rheumatoid Arthritis Arthritis & rheumatology (Hoboken, N.J.) 2017;69 (1):70-76 [PubMed]
  • Sprokholt Joris K., Heineke Marieke H., Kaptein Tanja M., van Hamme John L., Geijtenbeek Teunis B. H. DCs facilitate B cell responses against microbial DNA via DC-SIGN PLoS ONE 2017;12 (10):e0185580 [PubMed]
  • Noguchi Shuhei, Arakawa Takahiro, Fukuda Shiro, Furuno Masaaki, Hasegawa Akira, Hori Fumi, Ishikawa-Kato Sachi, Kaida Kaoru, Kaiho Ai, Kanamori-Katayama Mutsumi, Kawashima Tsugumi, Kojima Miki, Kubosaki Atsutaka, Manabe Ri-ichiroh, Murata Mitsuyoshi, Nagao-Sato Sayaka, Nakazato Kenichi, Ninomiya Noriko, Nishiyori-Sueki Hiromi, Noma Shohei, Saijyo Eri, Saka Akiko, Sakai Mizuho, Simon Christophe, Suzuki Naoko, Tagami Michihira, Watanabe Shoko, Yoshida Shigehiro, Arner Peter, Axton Richard A., Babina Magda, Baillie J. Kenneth, Barnett Timothy C., Beckhouse Anthony G., Blumenthal Antje, Bodega Beatrice, Bonetti Alessandro, Briggs James, Brombacher Frank, Carlisle Ailsa J., Clevers Hans C., Davis Carrie A., Detmar Michael, Dohi Taeko, Edge Albert S. B., Edinger Matthias, Ehrlund Anna, Ekwall Karl, Endoh Mitsuhiro, Enomoto Hideki, Eslami Afsaneh, Fagiolini Michela, Fairbairn Lynsey, Farach-Carson Mary C., Faulkner Geoffrey J., Ferrai Carmelo, Fisher Malcolm E., Forrester Lesley M., Fujita Rie, Furusawa Jun-ichi, Geijtenbeek Teunis B., Gingeras Thomas, Goldowitz Daniel, Guhl Sven, Guler Reto, Gustincich Stefano, Ha Thomas J., Hamaguchi Masahide, Hara Mitsuko, Hasegawa Yuki, Herlyn Meenhard, Heutink Peter, Hitchens Kelly J., Hume David A., Ikawa Tomokatsu, Ishizu Yuri, Kai Chieko, Kawamoto Hiroshi, Kawamura Yuki I., Kempfle Judith S., Kenna Tony J., Kere Juha, Khachigian Levon M., Kitamura Toshio, Klein Sarah, Klinken S. Peter, Knox Alan J., Kojima Soichi, Koseki Haruhiko, Koyasu Shigeo, Lee Weonju, Lennartsson Andreas, Mackay-sim Alan, Mejhert Niklas, Mizuno Yosuke, Morikawa Hiromasa, Morimoto Mitsuru, Moro Kazuyo, Morris Kelly J., Motohashi Hozumi, Mummery Christine L., Nakachi Yutaka, Nakahara Fumio, Nakamura Toshiyuki, Nakamura Yukio, Nozaki Tadasuke, Ogishima Soichi, Ohkura Naganari, Ohno Hiroshi, Ohshima Mitsuhiro, Okada-Hatakeyama Mariko, Okazaki Yasushi, Orlando Valerio, Ovchinnikov Dmitry A., Passier Robert, Patrikakis Margaret, Pombo Ana, Pradhan-Bhatt Swati, Qin Xian-Yang, Rehli Michael, Rizzu Patrizia, Roy Sugata, Sajantila Antti, Sakaguchi Shimon, Sato Hiroki, Satoh Hironori, Savvi Suzana, Saxena Alka, Schmidl Christian, Schneider Claudio, Schulze-Tanzil Gundula G., Schwegmann Anita, Sheng Guojun, Shin Jay W., Sugiyama Daisuke, Sugiyama Takaaki, Summers Kim M., Takahashi Naoko, Takai Jun, Tanaka Hiroshi, Tatsukawa Hideki, Tomoiu Andru, Toyoda Hiroo, van de Wetering Marc, van den Berg Linda M., Verardo Roberto, Vijayan Dipti, Wells Christine A., Winteringham Louise N., Wolvetang Ernst, Yamaguchi Yoko, Yamamoto Masayuki, Yanagi-Mizuochi Chiyo, Yoneda Misako, Yonekura Yohei, Zhang Peter G., Zucchelli Silvia, Abugessaisa Imad, Arner Erik, Harshbarger Jayson, Kondo Atsushi, Lassmann Timo, Lizio Marina, Sahin Serkan, Sengstag Thierry, Severin Jessica, Shimoji Hisashi, Suzuki Masanori, Suzuki Harukazu, Kawai Jun, Kondo Naoto, Itoh Masayoshi, Daub Carsten O., Kasukawa Takeya, Kawaji Hideya, Carninci Piero, Forrest Alistair R. R., Hayashizaki Yoshihide FANTOM5 CAGE profiles of human and mouse samples Scientific data 2017;4:170112 [PubMed]
  • Gringhuis Sonja I., Hertoghs Nina, Kaptein Tanja M., Zijlstra-Willems Esther M., Sarrami-Fooroshani Ramin, Sprokholt Joris K., van Teijlingen Nienke H., Kootstra Neeltje A., Booiman Thijs, van Dort Karel A., Ribeiro Carla M. S., Drewniak Agata, Geijtenbeek Teunis B. H. HIV-1 blocks the signaling adaptor MAVS to evade antiviral host defense after sensing of abortive HIV-1 RNA by the host helicase DDX3 Nature immunology 2017;18 (2):225-235 [PubMed]
  • Gringhuis Sonja I., Hertoghs Nina, Kaptein Tanja M., Zijlstra-Willems Esther M., Sarrami-Fooroshani Ramin, Sprokholt Joris K., van Teijlingen Nienke H., Kootstra Neeltje A., Booiman Thijs, van Dort Karel A., Ribeiro Carla M. S., Drewniak Agata, Geijtenbeek Teunis B. H. HIV-1 blocks the signaling adaptor MAVS to evade antiviral host defense after sensing of abortive HIV-1 RNA by the host helicase DDX3 (vol 18, pg 225, 2017) Nature immunology 2017;18 (4):474 [PubMed]
  • Bartelsman M., Joore I. K., van Bergen J. E., Hogewoning A. A., Zuure F. R., van Veen M. G., Deug F., Heidenrijk M., Prins J. M., Prins M. [= Maria], Smit P. J., van der Valk M., Reiss P., de Bree G. J., Hoornenborg E., Davidovich U., Geerlings S. E., Oomen A., van sighem A., Zuilhof W., Achterbergh R. C. A., van Agtmael M., Ananworanich J., van de Beek D., van den Berk G. E. L., Berkhout B., Berretty B., Bezemer D., Blok W. L., Bomers M., Boucher C. A. B., Brokking W., Burger D., Brinkman K., de Bruin M., Geijtenbeek T. B. H., Godfried M. H., Goorhuis A., van der Helm J. J., Hovius J. W., Kootstra N. A., van der Meer J. T., Nellen F. J., Pasternak A. O., van der Poll T., van Rooijen M. S., de Vries H. J., van Vugt M., Wiersinga W. J., Wit F. W. HIV testing week 2015: lowering barriers for HIV testing among high-risk groups in Amsterdam BMC infectious diseases 2017;17 (1):529 [PubMed]
  • Stelma Femke Immune responses in hepatitis B and C virus infection 2017. 286p. ISBN 9789461828347. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Beuers U. H. W., Geijtenbeek T. B. H.; Co-supervisors: Reesink H. W., Kootstra N. A.)
  • Hertoghs Nina, Geijtenbeek Teunis B. H., Ribeiro Carla M. S. Interplay between HIV-1 innate sensing and restriction in mucosal dendritic cells: balancing defense and viral transmission Current opinion in virology 2017;22:112-119 [PubMed]
  • Hertoghs Nina, van Pul Lisa, Geijtenbeek Teunis B. H. Mucosal dendritic cells in HIV-1 susceptibility: a critical role for C-type lectin receptors Future Virology 2017;12 (7):373-388
  • Schreurs R. R. C. E., Drewniak A., Bakx R., Corpeleijn W. E., Geijtenbeek T. H. B., van Goudoever J. B., Bunders M. J. Quantitative comparison of human intestinal mononuclear leukocyte isolation techniques for flow cytometric analyses Journal of immunological methods 2017;445:45-52 [PubMed]
  • Sprokholt Joris K., Kaptein Tanja M., van Hamme John L., Overmars Ronald J., Gringhuis Sonja I., Geijtenbeek Teunis B. H. RIG-I-like receptor activation by dengue virus drives follicular T helper cell formation and antibody production PLoS pathogens 2017;13 (11):e1006738 [PubMed]
  • Sprokholt Joris K., Kaptein Tanja M., van Hamme John L., Overmars Ronald J., Gringhuis Sonja I., Geijtenbeek Teunis B. H. RIG-I-like Receptor Triggering by Dengue Virus Drives Dendritic Cell Immune Activation and TH1 Differentiation Journal of immunology (Baltimore, Md. 2017;198 (12):4764-4771 [PubMed]

2016

  • Mason Lauren M. K., Wagemakers Alex, van 't Veer Cornelis, Oei Anneke, van der Pot Wouter J., Ahmed Kalam, van der Poll Tom, Geijtenbeek Teunis B. H., Hovius Joppe W. R. Borrelia burgdorferi Induces TLR2-Mediated Migration of Activated Dendritic Cells in an Ex Vivo Human Skin Model PLoS ONE 2016;11 (10):e0164040 [PubMed]
  • Borgdorff H., Gautam R., Armstrong S. D., Xia D., Ndayisaba G. F., van Teijlingen N. H., Geijtenbeek T. B. H., Wastling J. M., van de Wijgert J. H. H. M. Cervicovaginal microbiome dysbiosis is associated with proteome changes related to alterations of the cervicovaginal mucosal barrier Mucosal immunology 2016;9 (3):621-633 [PubMed]
  • Geijtenbeek Teunis B. H., Gringhuis Sonja I. C-type lectin receptors in the control of T helper cell differentiation Nature reviews. Immunology 2016;16 (7):433-448 [PubMed]
  • Sprokholt Joris K., Hertoghs Nina, Geijtenbeek Teunis B. H. Flow Cytometry-Based Bead-Binding Assay for Measuring Receptor Ligand Specificity Methods in molecular biology (Clifton, N.J.) 2016;1390:121-129 [PubMed]
  • Setiawan Laurentia C. HIV-1 adaptation to the host: The viral capsid and host factors 2016. 143p. ISBN 9789462993020. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Geijtenbeek T. B. H.; Co-supervisor: Kootstra N. A.)
  • Tytgat Hanne L. P., van Teijlingen Nienke H., Sullan Ruby May A., Douillard François P., Rasinkangas Pia, Messing Marcel, Reunanen Justus, Satokari Reetta, Vanderleyden Jos, Dufrêne Yves F., Geijtenbeek Teunis B. H., de Vos Willem M., Lebeer Sarah Probiotic Gut Microbiota Isolate Interacts with Dendritic Cells via Glycosylated Heterotrimeric Pili PLoS ONE 2016;11 (3):e0151824 [PubMed]
  • Ribeiro Carla M. S., Sarrami-Forooshani Ramin, Setiawan Laurentia C., Zijlstra-Willems Esther M., van Hamme John L., Tigchelaar Wikky, van der Wel Nicole N., Kootstra Neeltje A., Gringhuis Sonja I., Geijtenbeek Teunis B. H. Receptor usage dictates HIV-1 restriction by human TRIM5α in dendritic cell subsets Nature 2016;540 (7633):448-452 [PubMed]

2015

  • Carbajo Daniel, Magi Shigeyuki, Itoh Masayoshi, Kawaji Hideya, Lassmann Timo, Arner Erik, Forrest Alistair R. R., Carninci Piero, Hayashizaki Yoshihide, Daub Carsten O., Okada-Hatakeyama Mariko, Mar Jessica C., Rehli Michael, Baillie J. Kenneth, de Hoon Michiel J. L., Haberle Vanja, Kulakovskiy Ivan V., Lizio Marina, Andersson Robin, Mungall Christopher J., Meehan Terrence F., Schmeier Sebastian, Bertin Nicolas, Jørgensen Mette, Dimont Emmanuel, Schmidl Christian, Schaefer Ulf, Medvedeva Yulia A., Plessy Charles, Vitezic Morana, Severin Jessica, Semple Colin A., Ishizu Yuri, Francescatto Margherita, Alam Intikhab, Albanese Davide, Altschuler Gabriel M., Archer John A. C., Arner Peter, Babina Magda, Baker Sarah, Balwierz Piotr J., Beckhouse Anthony G., Pradhan-Bhatt Swati, Blake Judith A., Blumenthal Antje, Bodega Beatrice, Bonetti Alessandro, Briggs James, Geijtenbeek Teunis B. Application of Gene Expression Trajectories Initiated from ErbB Receptor Activation Highlights the Dynamics of Divergent Promoter Usage PLoS ONE 2015;10 (12):e0144176 [PubMed]
  • Tjon Angela S. W., van Gent Rogier, Geijtenbeek Teunis B., Kwekkeboom Jaap Differences in anti-inflammatory actions of intravenous immunoglobulin between mice and men: more than meets the eye Frontiers in immunology 2015;6:197 [PubMed]
  • Yoshihara Masahito, Ohmiya Hiroko, Hara Susumu, Kawasaki Satoshi, Hayashizaki Yoshihide, Itoh Masayoshi, Kawaji Hideya, Tsujikawa Motokazu, Nishida Kohji, Forrest Alistair R. R., Rehli Michael, Baillie J. Kenneth, de Hoon Michiel J. L., Haberle Vanja, Lassmann Timo, Kulakovskiy Ivan V., Lizio Marina, Andersson Robin, Mungall Christopher J., Meehan Terrence F., Schmeier Sebastian, Bertin Nicolas, Jørgensen Mette, Dimont Emmanuel, Arner Erik, Schmidl Christian, Schaefer Ulf, Medvedeva Yulia A., Plessy Charles, Vitezic Morana, Severin Jessica, Semple Colin A., Ishizu Yuri, Francescatto Margherita, Alam Intikhab, Albanese Davide, Altschuler Gabriel M., Archer John A. C., Arner Peter, Babina Magda, Baker Sarah, Balwierz Piotr J., Beckhouse Anthony G., Pradhan-Bhatt Swati, Blake Judith A., Blumenthal Antje, Bodega Beatrice, Bonetti Alessandro, Briggs James, Geijtenbeek Teunis B. Discovery of Molecular Markers to Discriminate Corneal Endothelial Cells in the Human Body PLoS ONE 2015;10 (3):e0117581 [PubMed]
  • Cobos Jiménez Viviana, Martinez Fernando O., Booiman Thijs, van Dort Karel A., van de Klundert Maarten A. A., Gordon Siamon, Geijtenbeek Teunis B. H., Kootstra Neeltje A. G3BP1 restricts HIV-1 replication in macrophages and T-cells by sequestering viral RNA Virology 2015;486:94-104 [PubMed]
  • Mirzaee Saeedeh, Drewniak Agata, Sarrami-Forooshani Ramin, Kaptein Tanja M., Gharibdoost Farhad, Geijtenbeek Teunis B. H. Herbal medicine IMOD suppresses LPS-induced production of proinflammatory cytokines in human dendritic cells Frontiers in pharmacology 2015;6:64 [PubMed]
  • Ribeiro Carla M. S., Sarrami-Forooshani Ramin, Geijtenbeek Teunis B. H. HIV-1 border patrols: Langerhans cells control antiviral responses and viral transmission Future Virology 2015;10 (11):1231-1243
  • Booiman Thijs Host factors in HIV-1 replication: The good, the bad and the ugly 2015. 214p. ISBN 9789053359747. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Geijtenbeek T. B. H.; Co-supervisor: Kootstra N. A.)
  • Wilflingseder Doris, Schroll Andrea, Hackl Hubert, Gallasch Ralf, Frampton Dan, Lass-Flörl Cornelia, Pancino Gianfranco, Saez-Cirion Asier, Lambotte Olivier, Weiss Laurence, Kellam Paul, Trajanoski Zlatko, Geijtenbeek Teunis, Weiss Günter, Posch Wilfried Immediate T-Helper 17 Polarization Upon Triggering CD11b/c on HIV-Exposed Dendritic Cells Journal of infectious diseases 2015;212 (1):44-56 [PubMed]
  • van den Berg Linda M., Cardinaud Sylvain, van der Aar Angelic M. G., Sprokholt Joris K., de Jong Marein A. W. P., Zijlstra-Willems Esther M., Moris Arnaud, Geijtenbeek Teunis B. H. Langerhans Cell-Dendritic Cell Cross-Talk via Langerin and Hyaluronic Acid Mediates Antigen Transfer and Cross-Presentation of HIV-1 Journal of immunology (Baltimore, Md. 2015;195 (4):1763-1773 [PubMed]
  • Hertoghs Nina, van der Aar Angelic M. G., Setiawan Laurentia C., Kootstra Neeltje A., Gringhuis Sonja I., Geijtenbeek Teunis B. H. SAMHD1 degradation enhances active suppression of dendritic cell maturation by HIV-1 Journal of immunology (Baltimore, Md. 2015;194 (9):4431-4437 [PubMed]
  • Hurst Laurence D., Ghanbarian Avazeh T., Forrest Alistair R. R., Huminiecki Lukasz, Kawaji Hideya, Rehli Michael, Baillie J. Kenneth, de Hoon Michiel J. L., Haberle Vanja, Lassmann Timo, Kulakovskiy Ivan V., Lizio Marina, Itoh Masayoshi, Andersson Robin, Mungall Christopher J., Meehan Terrence F., Schmeier Sebastian, Bertin Nicolas, Jørgensen Mette, Dimont Emmanuel, Arner Erik, Schmidl Christian, Schaefer Ulf, Medvedeva Yulia A., Plessy Charles, Vitezic Morana, Severin Jessica, Semple Colin A., Ishizu Yuri, Young Robert S., Francescatto Margherita, Alam Intikhab, Albanese Davide, Altschuler Gabriel M., Arakawa Takahiro, Archer John A. C., Arner Peter, Babina Magda, Baker Sarah, Balwierz Piotr J., Beckhouse Anthony G., Pradhan-Bhatt Swati, Blake Judith A., Blumenthal Antje, Bodega Beatrice, Bonetti Alessandro, Briggs James, Brombacher Frank, Burroughs A. Maxwell, Geijtenbeek Teunis B. The Constrained Maximal Expression Level Owing to Haploidy Shapes Gene Content on the Mammalian X Chromosome PLoS biology 2015;13 (12):e1002315 [PubMed]
  • Liang Cong, Forrest Alistair R. R., Wagner Günter P., Alam Intikhab, Albanese Davide, Altschuler Gabriel, Andersson Robin, Arakawa Takahiro, Archer John, Arner Erik, Arner Peter, Babina Magda, Baillie Kenneth, Bajic Vladmir, Baker Sarah, Balic Adam, Balwierz Piotr, Beckhouse Anthony, Bertin Nicolas, Blake Judith A., Blumenthal Antje, Bodega Beatrice, Bonetti Alessandro, Briggs James, Brombacher Frank, Burroughs Max, Califano Andrea, Cannistraci Carlo, Carbajo Daniel, Carninci Piero, Chen Yun, Chierici Marco, Ciani Yari, Clevers Hans, Dalla Emiliano, Daub Carsten, Davis Carrie, de Hoon Michiel, de Lima Morais David, Dermar Michael, Diehl Alexander, Dimont Emmanuel, Dohl Taeko, Drabros Finn, Edge Albert, Edinger Matthias, Ekwall Karl, Endoh Mitsuhiro, Enomoto Hideki, Geijtenbeek Teunis B. H. The statistical geometry of transcriptome divergence in cell-type evolution and cancer Nature communications 2015;6:6066 [PubMed]
  • Joshi Anagha, Pooley Christopher, Freeman Tom C., Lennartsson Andreas, Babina Magda, Schmidl Christian, Geijtenbeek Teunis, Michoel Tom, Severin Jessica, Itoh Masayoshi, Lassmann Timo, Kawaji Hideya, Hayashizaki Yoshihide, Carninci Piero, Forrest Alistair R. R., Rehli Michael, Hume David A. Transcription factor, promoter, and enhancer utilization in human myeloid cells Journal of leukocyte biology 2015;97 (5):985-995 [PubMed]

2014

  • Andersson Robin, Gebhard Claudia, Miguel-Escalada Irene, Hoof Ilka, Bornholdt Jette, Boyd Mette, Chen Yun, Zhao Xiaobei, Schmidl Christian, Suzuki Takahiro, Ntini Evgenia, Arner Erik, Valen Eivind, Li Kang, Schwarzfischer Lucia, Glatz Dagmar, Raithel Johanna, Lilje Berit, Rapin Nicolas, Bagger Frederik Otzen, Jørgensen Mette, Andersen Peter Refsing, Bertin Nicolas, Rackham Owen, Burroughs A. Maxwell, Baillie J. Kenneth, Ishizu Yuri, Shimizu Yuri, Furuhata Erina, Maeda Shiori, Negishi Yutaka, Mungall Christopher J., Meehan Terrence F., Lassmann Timo, Itoh Masayoshi, Kawaji Hideya, Kondo Naoto, Kawai Jun, Lennartsson Andreas, Daub Carsten O., Heutink Peter, Hume David A., Jensen Torben Heick, Suzuki Harukazu, Hayashizaki Yoshihide, Müller Ferenc, Forrest Alistair R. R., Carninci Piero, Geijtenbeek Teunis B., Gibson Andrew P. An atlas of active enhancers across human cell types and tissues Nature 2014;507 (7493):455-461 [PubMed]
  • Davis Meredith E., Wang May K., Rennick Linda J., Full Florian, Gableske Sebastian, Mesman Annelies W., Gringhuis Sonja I., Geijtenbeek Teunis B. H., Duprex W. Paul, Gack Michaela U. Antagonism of the Phosphatase PP1 by the Measles Virus V Protein Is Required for Innate Immune Escape of MDA5 Cell host & microbe 2014;16 (1):19-30 [PubMed]
  • Forrest Alistair R. R., Kawaji Hideya, Rehli Michael, Baillie J. Kenneth, de Hoon Michiel J. L., Haberle Vanja, Lassmann Timo, Kulakovskiy Ivan V., Lizio Marina, Itoh Masayoshi, Andersson Robin, Mungall Christopher J., Meehan Terrence F., Schmeier Sebastian, Bertin Nicolas, Jørgensen Mette, Dimont Emmanuel, Arner Erik, Schmidl Christian, Schaefer Ulf, Medvedeva Yulia A., Plessy Charles, Vitezic Morana, Severin Jessica, Semple Colin A., Ishizu Yuri, Young Robert S., Francescatto Margherita, Alam Intikhab, Albanese Davide, Altschuler Gabriel M., Arakawa Takahiro, Archer John A. C., Arner Peter, Babina Magda, Rennie Sarah, Balwierz Piotr J., Beckhouse Anthony G., Pradhan-Bhatt Swati, Blake Judith A., Blumenthal Antje, Bodega Beatrice, Bonetti Alessandro, Briggs James, Brombacher Frank, Burroughs A. Maxwell, Califano Andrea, Cannistraci Carlo V., Geijtenbeek Teunis B., Gibson Andrew P. A promoter-level mammalian expression atlas Nature 2014;507 (7493):462-+ [PubMed]
  • van den Berg Linda M., Ribeiro Carla M. S., Zijlstra-Willems Esther M., de Witte Lot, Fluitsma Donna, Tigchelaar Wikky, Everts Vincent, Geijtenbeek Teunis B. H. Caveolin-1 mediated uptake via langerin restricts HIV-1 infection in human Langerhans cells Retrovirology 2014;11 (1):123 [PubMed]
  • Hasegawa Yuki, Tang Dave, Takahashi Naoko, Hayashizaki Yoshihide, Forrest Alistair R. R., Suzuki Harukazu, Kawaji Hideya, Rehli Michael, Baillie J. Kenneth, de Hoon Michiel J. L., Haberle Vanja, Lassmann Timo, Kulakovskiy Ivan V., Lizio Marina, Itoh Masayoshi, Andersson Robin, Mungall Christopher J., Meehan Terrence F., Schmeier Sebastian, Bertin Nicolas, Jørgensen Mette, Dimont Emmanuel, Arner Erik, Schmidl Christian, Schaefer Ulf, Medvedeva Yulia A., Plessy Charles, Vitezic Morana, Severin Jessica, Semple Colin A., Ishizu Yuri, Young Robert S., Francescatto Margherita, Alam Intikhab, Albanese Davide, Altschuler Gabriel M., Arakawa Takahiro, Archer John A. C., Arner Peter, Babina Magda, Baker Sarah, Balwierz Piotr J., Beckhouse Anthony G., Pradhan-Bhatt Swati, Blake Judith A., Blumenthal Antje, Bodega Beatrice, Bonetti Alessandro, Briggs James, Geijtenbeek Teunis B. CCL2 enhances pluripotency of human induced pluripotent stem cells by activating hypoxia related genes Scientific reports 2014;4:5228 [PubMed]
  • Arner Erik, Forrest Alistair R. R., Ehrlund Anna, Mejhert Niklas, Itoh Masayoshi, Kawaji Hideya, Lassmann Timo, Laurencikiene Jurga, Rydén Mikael, Arner Peter, Rehli Michael, Baillie J. Kenneth, de Hoon Michiel J. L., Haberle Vanja, Kulakovskiy Ivan V., Lizio Marina, Andersson Robin, Mungall Christopher J., Meehan Terrence F., Schmeier Sebastian, Bertin Nicolas, Jørgensen Mette, Dimont Emmanuel, Schmidl Christian, Schaefer Ulf, Medvedeva Yulia A., Plessy Charles, Vitezic Morana, Severin Jessica, Semple Colin A., Ishizu Yuri, Francescatto Margherita, Alam Intikhab, Albanese Davide, Altschuler Gabriel M., Archer John A. C., Babina Magda, Baker Sarah, Balwierz Piotr J., Beckhouse Anthony G., Pradhan-Bhatt Swati, Blake Judith A., Blumenthal Antje, Bodega Beatrice, Bonetti Alessandro, Briggs James, Brombacher Frank, Burroughs A. Maxwell, Califano Andrea, Geijtenbeek Teunis B. Ceruloplasmin Is a Novel Adipokine Which Is Overexpressed in Adipose Tissue of Obese Subjects and in Obesity-Associated Cancer Cells PLoS ONE 2014;9 (3):e80274 [PubMed]
  • Wevers Brigitte A. C-type lectin signaling in dendritic cells. Molecular control of antifungal inflammation 2014. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Geijtenbeek T. B. H.; Co-supervisor: Gringhuis S. I.)
  • van den Berg Linda M., Zijlstra-Willems Esther M., Richters Cornelia D., Ulrich Magda M. W., Geijtenbeek Teunis B. H. Dectin-1 activation induces proliferation and migration of human keratinocytes enhancing wound re-epithelialization Cellular immunology 2014;289 (1-2):49-54 [PubMed]
  • Morikawa Hiromasa, Ohkura Naganari, Vandenbon Alexis, Itoh Masayoshi, Nagao-Sato Sayaka, Kawaji Hideya, Lassmann Timo, Carninci Piero, Hayashizaki Yoshihide, Forrest Alistair R. R., Standley Daron M., Date Hiroshi, Sakaguchi Shimon, Rehli Michael, Baillie J. Kenneth, de Hoon Michiel J. L., Haberle Vanja, Kulakovskiy Ivan V., Lizio Marina, Andersson Robin, Mungall Christopher J., Meehan Terrence F., Schmeier Sebastian, Bertin Nicolas, Jørgensen Mette, Dimont Emmanuel, Arner Erik, Schmidl Christian, Schaefer Ulf, Medvedeva Yulia A., Plessy Charles, Vitezic Morana, Severin Jessica, Semple Colin A., Ishizu Yuri, Francescatto Margherita, Alam Intikhab, Albanese Davide, Altschuler Gabriel M., Archer John A. C., Arner Peter, Babina Magda, Baker Sarah, Balwierz Piotr J., Beckhouse Anthony G., Pradhan-Bhatt Swati, Blake Judith A., Blumenthal Antje, Bodega Beatrice, Geijtenbeek Teunis B. Differential roles of epigenetic changes and Foxp3 expression in regulatory T cell-specific transcriptional regulation Proceedings of the National Academy of Sciences of the United States of America 2014;111 (14):5289-5294 [PubMed]
  • Pingen Marieke, Sarrami-Forooshani Ramin, Wensing Annemarie M. J., van Ham Petra, Drewniak Agata, Boucher Charles A. B., Geijtenbeek Teunis B. H., Nijhuis Monique Diminished transmission of drug resistant HIV-1 variants with reduced replication capacity in a human transmission model Retrovirology 2014;11 (1):113 [PubMed]
  • Gringhuis Sonja I., Kaptein Tanja M., Wevers Brigitte A., van der Vlist Michiel, Klaver Elsenoor J., van Die Irma, Vriend Lianne E. M., de Jong Marein A. W. P., Geijtenbeek Teunis B. H. Fucose-based PAMPs prime dendritic cells for follicular T helper cell polarization via DC-SIGN-dependent IL-27 production Nature communications 2014;5:5074 [PubMed]
  • Gringhuis Sonja I., Kaptein Tanja M., Wevers Brigitte A., Mesman Annelies W., Geijtenbeek Teunis B. H. Fucose-specific DC-SIGN signalling directs T helper cell type-2 responses via IKKε- and CYLD-dependent Bcl3 activation Nature communications 2014;5:3898 [PubMed]
  • Wevers Brigitte A., Kaptein Tanja M., Zijlstra-Willems Esther M., Theelen Bart, Boekhout Teun, Geijtenbeek Teunis B. H., Gringhuis Sonja I. Fungal engagement of the C-type lectin mincle suppresses dectin-1-induced antifungal immunity Cell host & microbe 2014;15 (4):494-505 [PubMed]
  • Cobos Jiménez Viviana HIV-1 infection in macrophages and genes involved throughout: big eaters versus small invaders 2014. 171p. ISBN 9789461824127. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Geijtenbeek T. B. H.; Co-supervisor: Kootstra N. A.)
  • Mesman Annelies W. Host-pathogen interplay in viral transmission and immune evasion 2014. 163p. ISBN 9789461824165. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Geijtenbeek T. B. H.; Co-supervisor: Gringhuis S. I.)
  • Sarrami-Forooshani Ramin, Mesman Annelies W., van Teijlingen Nienke H., Sprokholt Joris K., van der Vlist Michiel, Ribeiro Carla M. S., Geijtenbeek Teunis B. H. Human immature Langerhans cells restrict CXCR4-using HIV-1 transmission Retrovirology 2014;11 (1):52 [PubMed]
  • Mesman Annelies W., Zijlstra-Willems Esther M., Kaptein Tanja M., de Swart Rik L., Davis Meredith E., Ludlow Martin, Duprex W. Paul, Gack Michaela U., Gringhuis Sonja I., Geijtenbeek Teunis B. H. Measles Virus Suppresses RIG-I-like Receptor Activation in Dendritic Cells via DC-SIGN-Mediated Inhibition of PP1 Phosphatases Cell host & microbe 2014;16 (1):31-42 [PubMed]
  • Mason Lauren M. K., Veerman Christiaan C., Geijtenbeek Teunis B. H., Hovius Joppe W. R. Menage a trois: Borrelia, dendritic cells, and tick saliva interactions Trends in parasitology 2014;30 (2):95-103 [PubMed]

2013

  • Geijtenbeek Teunis B. H., Gringhuis Sonja I. An inside job for antibodies: tagging pathogens for intracellular sensing Nature immunology 2013;14 (4):309-311 [PubMed]
  • van den Berg Linda M., Geijtenbeek Teunis B. H. Antiviral Immune Responses by Human Langerhans Cells and Dendritic Cells in HIV-1 Infection Advances in experimental medicine and biology 2013;762:45-70 [PubMed]
  • Wevers Brigitte A., Geijtenbeek Teunis B. H., Gringhuis Sonja I. C-type lectin receptors orchestrate antifungal immunity Future microbiology 2013;8 (7):839-854 [PubMed]
  • Mayumi Nobuko, Watanabe Eri, Norose Yoshihiko, Watari Eiji, Kawana Seiji, Geijtenbeek Teunis B. H., Takahashi Hidemi E-cadherin interactions are required for Langerhans cell differentiation European journal of immunology 2013;43 (1):270-280 [PubMed]
  • Garcia-Vallejo Juan J., Koning Nathalie, Ambrosini Martino, Kalay Hakan, Vuist Ilona, Sarrami-Forooshani Ramin, Geijtenbeek Teunis B. H., van Kooyk Yvette Glycodendrimers prevent HIV transmission via DC-SIGN on dendritic cells International immunology 2013;25 (4):221-233 [PubMed]
  • Brunen Diede, Mesman Annelies W., Geijtenbeek Teunis B. H. RIG-I-like receptors and intracellular Toll-like receptors in antiviral immunity Future Virology 2013;8 (2):183-194
  • van den Berg Linda M. The role of C-type lectin receptors in human skin immunity. Immunological interactions between dendritic cells, Langerhans cells and keratinocytes 2013. 133p. ISBN 9789462032668. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Geijtenbeek T. B. H.)

2012

  • Geijtenbeek Teunis B. H. Actin' as a Death Signal Immunity 2012;36 (4):557-559 [PubMed]
  • van den Berg Linda M., Gringhuis Sonja I., Geijtenbeek Teunis B. H. An evolutionary perspective on C-type lectins in infection and immunity Annals of the New York Academy of Sciences 2012;1253:149-158 [PubMed]
  • Mesman Annelies W., de Vries Rory D., McQuaid Stephen, Duprex W. Paul, de Swart Rik L., Geijtenbeek Teunis B. H. A Prominent Role for DC-SIGN(+) Dendritic Cells in Initiation and Dissemination of Measles Virus Infection in Non-Human Primates PLoS ONE 2012;7 (12):e49573 [PubMed]
  • van der Vlist Michiel C-type lectins on dendritic cells. Bittersweet interactions with viruses 2012. 151p. ISBN 9789085708308. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Geijtenbeek T. B. H.; Co-supervisor: Gringhuis S. I.)
  • Gringhuis Sonja I., Kaptein Tanja M., Wevers Brigitte A., Theelen Bart, van der Vlist Michiel, Boekhout Teun, Geijtenbeek Teunis B. H. Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1 beta via a noncanonical caspase-8 inflammasome Nature immunology 2012;13 (3):246-U63 [PubMed]
  • Mesman Annelies W., Geijtenbeek Teunis B. Pattern recognition receptors in HIV transmission Frontiers in immunology 2012;3:59 [PubMed]
  • Sorvillo Nicoletta, Pos Wouter, van den Berg Linda M., Fijnheer Rob, Martinez-Pomares Luisa, Geijtenbeek Teunis B., Herczenik Eszter, Voorberg Jan The macrophage mannose receptor promotes uptake of ADAMTS13 by dendritic cells Blood 2012;119 (16):3828-3835 [PubMed]
  • de Vries Rory D., Mesman Annelies W., Geijtenbeek Teunis B. H., Duprex W. Paul, de Swart Rik L. The pathogenesis of measles Current opinion in virology 2012;2 (3):248-255 [PubMed]

2011

  • van den Berg Linda M., de Jong Marein A. W. P., Witte Lot de, Ulrich Magda M. W., Geijtenbeek Teunis B. H. Burn injury suppresses human dermal dendritic cell and Langerhans cell function Cellular immunology 2011;268 (1):29-36 [PubMed]
  • Lemon Ken, de Vries Rory D., Mesman Annelies W., McQuaid Stephen, van Amerongen Geert, Yüksel Selma, Ludlow Martin, Rennick Linda J., Kuiken Thijs, Rima Bertus K., Geijtenbeek Teunis B. H., Osterhaus Albert D. M. E., Duprex W. Paul, de Swart Rik L. Early Target Cells of Measles Virus after Aerosol Infection of Non-Human Primates PLoS pathogens 2011;7 (1):e1001263 [PubMed]
  • de Witte Lot, Bobardt Michael D., Chatterji Udayan, van Loenen Freek B., Verjans Georges M. G. M., Geijtenbeek Teunis B. H., Gallay Philippe A. HSV neutralization by the microbicidal candidate C5A PLoS ONE 2011;6 (5):e18917 [PubMed]
  • van der Vlist Michiel, de Witte Lot, de Vries Rory D., Litjens Manja, de Jong Marein A. W. P., Fluitsma Donna, de Swart Rik L., Geijtenbeek Teunis B. H. Human Langerhans cells capture measles virus through Langerin and present viral antigens to CD4⁺ T cells but are incapable of cross-presentation European journal of immunology 2011;41 (9):2619-2631 [PubMed]
  • van der Vlist Michiel, van der Aar Angelic M. G., Gringhuis Sonja I., Geijtenbeek Teunis B. H. Innate signaling in HIV-1 infection of dendritic cells Current opinion in HIV and AIDS 2011;6 (5):348-352 [PubMed]
  • Gringhuis Sonja I., Wevers Brigitte A., Kaptein Tanja M., van Capel Toni M. M., Theelen Bart, Boekhout Teun, de Jong Esther C., Geijtenbeek Teunis B. H. Selective C-Rel Activation via Malt1 Controls Anti-Fungal T-H-17 Immunity by Dectin-1 and Dectin-2 PLoS pathogens 2011;7 (1):e1001259 [PubMed]

2010

  • Gringhuis Sonja I., Geijtenbeek Teunis B. H. Carbohydrate signaling by C-type lectin DC-SIGN affects NF-kappaB activity Methods in enzymology 2010;480:151-164 [PubMed]
  • de Jong Marein A. W. P., Vriend Lianne E. M., Theelen Bart, Taylor Maureen E., Fluitsma Donna, Boekhout Teun, Geijtenbeek Teunis B. H. C-type lectin Langerin is a beta-glucan receptor on human Langerhans cells that recognizes opportunistic and pathogenic fungi Molecular immunology 2010;47 (6):1216-1225 [PubMed]
  • den Dunnen Jeroen, Gringhuis Sonja I., Geijtenbeek Teunis B. H. Dusting the sugar fingerprint: C-type lectin signaling in adaptive immunity Immunology letters 2010;128 (1):12-16 [PubMed]
  • de Jong Marein A. W. P., de Witte Lot, Taylor Maureen E., Geijtenbeek Teunis B. H. Herpes Simplex Virus Type 2 Enhances HIV-1 Susceptibility by Affecting Langerhans Cell Function Journal of immunology (Baltimore, Md. 2010;185 (3):1633-1641 [PubMed]
  • Gringhuis Sonja I., van der Vlist Michiel, van den Berg Linda M., den Dunnen Jeroen, Litjens Manja, Geijtenbeek Teunis B. H. HIV-1 exploits innate signaling by TLR8 and DC-SIGN for productive infection of dendritic cells Nature immunology 2010;11 (5):419-U81 [PubMed]
  • Geijtenbeek Teunis B. H. Host DNase TREX1 hides HIV from DNA sensors Nature immunology 2010;11 (11):979-980 [PubMed]
  • de Jong Marein A. W. P., de Witte Lot, Geijtenbeek Teunis B. H. Isolation of immature primary Langerhans cells from human epidermal skin Methods in molecular biology (Clifton, N.J.) 2010;595:55-65 [PubMed]
  • de Jong Marein A. W. P. Langerhans cells and dendritic cells in innate defense against pathogensAmsterdam: 2010. 229p. [UvA Dissertations Online] Vrije Universiteit Amsterdam: MCBI. (Supervisors: Geijtenbeek T. B. H., van Kooyk Y.)
  • de Jong Marein A. W. P., Geijtenbeek Teunis B. H. Langerhans cells in innate defense against pathogens Trends in immunology 2010;31 (12):452-459 [PubMed]
  • van der Vlist Michiel, Geijtenbeek Teunis B. H. Langerin functions as an antiviral receptor on Langerhans cells Immunology and cell biology 2010;88 (4):410-415 [PubMed]
  • de Jong Marein A. W. P., de Witte Lot, Santegoets Saskia J. A. M., Fluitsma Donna, Taylor Maureen E., de Gruijl Tanja D., Geijtenbeek Teunis B. H. Mutz-3-derived Langerhans cells are a model to study HIV-1 transmission and potential inhibitors Journal of leukocyte biology 2010;87 (4):637-643 [PubMed]
  • Nguyen D. Tien, de Witte Lot, Ludlow Martin, Yüksel Selma, Wiesmüller Karl-Heinz, Geijtenbeek Teunis B. H., Osterhaus Albert D. M. E., de Swart Rik L. The Synthetic Bacterial Lipopeptide Pam3CSK4 Modulates Respiratory Syncytial Virus Infection Independent of TLR Activation PLoS pathogens 2010;6 (8):e1001049 [PubMed]

2009

  • Gringhuis Sonja I., den Dunnen Jeroen, Litjens Manja, van der Vlist Michiel, Geijtenbeek Teunis B. H. Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori Nature immunology 2009;10 (10):1081-U58 [PubMed]
  • den Dunnen Jeroen C-type lectin signaling in response to pathogens 2009. 194p. ISBN 9789085702863. [UvA Dissertations Online] Vrije Universiteit Amsterdam: MCBI. (Supervisor: van Kooyk Y.; Co-supervisors: Geijtenbeek T. B. H., Gringhuis S. I.)
  • Gringhuis Sonja I., den Dunnen Jeroen, Litjens Manja, van der Vlist Michiel, Wevers Brigitte, Bruijns Sven C. M., Geijtenbeek Teunis B. H. Dectin-1 directs T helper cell differentiation by controlling noncanonical NF-kappaB activation through Raf-1 and Syk Nature immunology 2009;10 (2):203-213 [PubMed]
  • de Jong M. A. W. P., Geijtenbeek T. B. H. Human immunodeficiency virus-1 acquisition in genital mucosa: Langerhans cells as key-players Journal of internal medicine 2009;265 (1):18-28 [PubMed]
  • de Witte Lot, de Jong Marein A. W. P., den Dunnen Jeroen, van Kooyk Yvette, Geijtenbeek Teunis B. H. Identification of pathogen receptors on dendritic cells to understand their function and to identify new drug targets Methods in molecular biology (Clifton, N.J.) 2009;531:267-285 [PubMed]
  • den Dunnen Jeroen, Gringhuis Sonja I., Geijtenbeek Teunis B. H. Innate signaling by the C-type lectin DC-SIGN dictates immune responses Cancer immunology, immunotherapy 2009;58 (7):1149-1157 [PubMed]
  • Saeland Eirikur, de Jong Marein A. W. P., Nabatov Alexey A., Kalay Hakan, Geijtenbeek Teunis B. H., van Kooyk Yvette MUC1 in human milk blocks transmission of human immunodeficiency virus from dendritic cells to T cells Molecular immunology 2009;46 (11-12):2309-2316 [PubMed]
  • Geijtenbeek Teunis B. H., den Dunnen Jeroen, Gringhuis Sonja I. Pathogen recognition by DC-SIGN shapes adaptive immunity Future microbiology 2009;4 (7):879-890 [PubMed]
  • Kooij Gijs, Backer Ronald, Koning Jasper J., Reijerkerk Arie, van Horssen Jack, van der Pol Susanne M. A., Drexhage Joost, Schinkel Alfred, Dijkstra Christine D., den Haan Joke M. M., Geijtenbeek Teunis B. H., de Vries Helga E. P-glycoprotein acts as an immunomodulator during neuroinflammation PLoS ONE 2009;4 (12):e8212 [PubMed]
  • Geijtenbeek Teunis B. H., Gringhuis Sonja I. Signalling through C-type lectin receptors: shaping immune responses Nature reviews. Immunology 2009;9 (7):465-479 [PubMed]
  • Op den Brouw Marjoleine L., Binda Rekha S., Geijtenbeek Teunis B. H., Janssen Harry L. A., Woltman Andrea M. The mannose receptor acts as hepatitis B virus surface antigen receptor mediating interaction with intrahepatic dendritic cells Virology 2009;393 (1):84-90 [PubMed]

2008

  • Op den Brouw M. L., de Jong M. A. W. P., Ludwig I. S., van der Molen R. G., Janssen H. L. A., Geijtenbeek T. B. H., Woltman A. M. Branched oligosaccharide structures on HBV prevent interaction with both DC-SIGN and L-SIGN Journal of viral hepatitis 2008;15 (9):675-683 [PubMed]
  • Nabatov Alexey A., de Jong Marein A. W. P., de Witte Lot, Bulgheresi Silvia, Geijtenbeek Teunis B. H. C-type lectin Mermaid inhibits dendritic cell mediated HIV-1 transmission to CD4+ T cells Virology 2008;378 (2):323-328 [PubMed]
  • de Witte Lot, de Vries Rory D., van der Vlist Michiel, Yüksel Selma, Litjens Manja, de Swart Rik L., Geijtenbeek Teunis B. H. DC-SIGN and CD150 have distinct roles in transmission of measles virus from dendritic cells to T-lymphocytes PLoS pathogens 2008;4 (4):e1000049 [PubMed]
  • García-Vallejo Juan J., van Liempt Ellis, da Costa Martins Paula, Beckers Cora, van het Hof Bert, Gringhuis Sonja I., Zwaginga Jaap-Jan, van Dijk Willem, Geijtenbeek Teunis B. H., van Kooyk Yvette, van Die Irma DC-SIGN mediates adhesion and rolling of dendritic cells on primary human umbilical vein endothelial cells through LewisY antigen expressed on ICAM-2 Molecular immunology 2008;45 (8):2359-2369 [PubMed]
  • de Witte Lot D. Dendritic cells and lymphotropic viruses: Who is fooling whom? 2008. 272p. ISBN 9788086592234. [UvA Dissertations Online] Vrije Universiteit Amsterdam: MCBI. (Supervisor: van Kooyk Y.; Co-supervisor: Geijtenbeek T. B. H.)
  • de Jong Marein A. W. P., de Witte Lot, Bolmstedt Anders, van Kooyk Yvette, Geijtenbeek Teunis B. H. Dendritic cells mediate herpes simplex virus infection and transmission through the C-type lectin DC-SIGN Journal of general virology 2008;89 (Part 10):2398-2409 [PubMed]
  • de Witte Lot, Nabatov Alexey, Geijtenbeek Teunis B. H. Distinct roles for DC-SIGN+-dendritic cells and Langerhans cells in HIV-1 transmission Trends in molecular medicine 2008;14 (1):12-19 [PubMed]
  • Bobardt Michael D., Cheng Guofeng, de Witte Lot, Selvarajah Suganya, Chatterji Udayan, Sanders-Beer Brigitte E., Geijtenbeek Teunis B. H., Chisari Francis V., Gallay Philippe A. Hepatitis C virus NS5A anchor peptide disrupts human immunodeficiency virus Proceedings of the National Academy of Sciences of the United States of America 2008;105 (14):5525-5530 [PubMed]
  • Koppel Estella A., Litjens Manja, van den Berg Venice C., van Kooyk Yvette, Geijtenbeek Teunis B. H. Interaction of SIGNR1 expressed by marginal zone macrophages with marginal zone B cells is essential to early IgM responses against Streptococcus pneumoniae Molecular immunology 2008;45 (10):2881-2887 [PubMed]
  • Cunningham Anthony L., Carbone Francis, Geijtenbeek Teunis B. H. Langerhans cells and viral immunity European journal of immunology 2008;38 (9):2377-2385 [PubMed]
  • Hovius Joppe W. R., de Jong Marein A. W. P., den Dunnen Jeroen, Litjens Manja, Fikrig Erol, van der Poll Tom, Gringhuis Sonja I., Geijtenbeek Teunis B. H. Salp15 binding to DC-SIGN inhibits cytokine expression by impairing both nucleosome remodeling and mRNA stabilization PLoS pathogens 2008;4 (2):e31 [PubMed]
  • van Vliet Sandra J., Paessens Lutz C., Broks-van den Berg Venice C. M., Geijtenbeek Teunis B. H., van Kooyk Yvette The C-type lectin macrophage galactose-type lectin impedes migration of immature APCs Journal of immunology (Baltimore, Md. 2008;181 (5):3148-3155 [PubMed]
  • Appelmelk B. J., den Dunnen J., Driessen N. N., Ummels R., Pak M., Nigou J., Larrouy-Maumus G., Gurcha S. S., Movahedzadeh F., Geurtsen J., Brown E. J., Eysink Smeets M. M., Besra G. S., Willemsen P. T. J., Lowary T. L., van Kooyk Y., Maaskant J. J., Stoker N. G., van der Ley P., Puzo G., Vandenbroucke-Grauls C. M. J. E., Wieland C. W., van der Poll T., Geijtenbeek T. B. H., van der Sar A. M., Bitter W. The mannose cap of mycobacterial lipoarabinomannan does not dominate the Mycobacterium-host interaction Cellular microbiology 2008;10 (4):930-944 [PubMed]
  • de Jong Marein A. W. P., de Witte Lot, Oudhoff Menno J., Gringhuis Sonja I., Gallay Philippe, Geijtenbeek Teunis B. H. TNF-alpha and TLR agonists increase susceptibility to HIV-1 transmission by human Langerhans cells ex vivo Journal of clinical investigation 2008;118 (10):3440-3452 [PubMed]

2007

  • Dasgupta Suryasarathi, Navarrete Ana-Maria, Bayry Jagadeesh, Delignat Sandrine, Wootla Bharath, André Sébastien, Christophe Olivier, Nascimbeni Michelina, Jacquemin Marc, Martinez-Pomares Luisa, Geijtenbeek Teunis B. H., Moris Arnaud, Saint-Remy Jean-Marie, Kazatchkine Michel D., Kaveri Srinivas V., Lacroix-Desmazes Sébastien A role for exposed mannosylations in presentation of human therapeutic self-proteins to CD4+ T lymphocytes Proceedings of the National Academy of Sciences of the United States of America 2007;104 (21):8965-8970 [PubMed]
  • de Witte Lot, Zoughlami Younes, Aengeneyndt Birgit, David Guido, van Kooyk Yvette, Gissmann Lutz, Geijtenbeek Teunis B. H. Binding of human papilloma virus L1 virus-like particles to dendritic cells is mediated through heparan sulfates and induces immune activation Immunobiology 2007;212 (9-10):679-691 [PubMed]
  • Gringhuis Sonja I., den Dunnen Jeroen, Litjens Manja, van het Hof Bert, van Kooyk Yvette, Geijtenbeek Teunis B. H. C-type lectin DC-SIGN modulates Toll-like receptor signaling via Raf-1 kinase-dependent acetylation of transcription factor NF-kappaB Immunity 2007;26 (5):605-616 [PubMed]
  • Ludwig Irene S. C-type lectins L-SIGN and DC-SIGN 2007. 192p. ISBN 9789086591244. [UvA Dissertations Online] Vrije Universiteit Amsterdam: MCBI. (Supervisor: van Kooyk Y.; Co-supervisor: Geijtenbeek T. B. H.)
  • van Montfort Thijs, Nabatov Alexey A., Geijtenbeek Teunis B. H., Pollakis Georgios, Paxton William A. Efficient capture of antibody neutralized HIV-1 by cells expressing DC-SIGN and transfer to CD4+ T lymphocytes Journal of immunology (Baltimore, Md. 2007;178 (5):3177-3185 [PubMed]
  • van Vliet Sandra J., den Dunnen Jeroen, Gringhuis Sonja I., Geijtenbeek Teunis Bh, van Kooyk Yvette Innate signaling and regulation of Dendritic cell immunity Current opinion in immunology 2007;19 (4):435-440 [PubMed]
  • de Witte Lot, Nabatov Alexey, Pion Marjorie, Fluitsma Donna, de Jong Marein A. W. P., de Gruijl Tanja, Piguet Vincent, van Kooyk Yvette, Geijtenbeek Teunis B. H. Langerin is a natural barrier to HIV-1 transmission by Langerhans cells Nature medicine 2007;13 (3):367-371 [PubMed]
  • van Vliet Sandra J., Aarnoudse Corlien A., Broks-van den Berg Venice C. M., Boks Martine, Geijtenbeek Teunis B. H., van Kooyk Yvette MGL-mediated internalization and antigen presentation by dendritic cells: a role for tyrosine-5 European journal of immunology 2007;37 (8):2075-2081 [PubMed]
  • Wieland Catharina W., Koppel Estella A., den Dunnen Jeroen, Florquin Sandrine, McKenzie Andrew N. J., van Kooyk Yvette, van der Poll Tom, Geijtenbeek Teunis B. H. Mice lacking SIGNR1 have stronger T helper 1 responses to Mycobacterium tuberculosis Microbes and infection / Institut Pasteur 2007;9 (2):134-141 [PubMed]
  • van Vliet Sandra J. Novel insights into MGL-glycan interactions in the immune system 2007. 232p. ISBN 9789090215747. [UvA Dissertations Online] Vrije Universiteit Amsterdam: MCBI. (Supervisor: van Kooyk Y.; Co-supervisor: Geijtenbeek T. B. H.)
  • de Swart Rik L., Ludlow Martin, de Witte Lot, Yanagi Yusuke, van Amerongen Geert, McQuaid Stephen, Yüksel Selma, Geijtenbeek Teunis B. H., Duprex W. Paul, Osterhaus Albert D. M. E. Predominant infection of CD150+ lymphocytes and dendritic cells during measles virus infection of macaques PLoS pathogens 2007;3 (11):e178 [PubMed]
  • de Witte Lot, Bobardt Michael, Chatterji Udayan, Degeest Gisèle, David Guido, Geijtenbeek Teunis B. H., Gallay Philippe Syndecan-3 is a dendritic cell-specific attachment receptor for HIV-1 Proceedings of the National Academy of Sciences of the United States of America 2007;104 (49):19464-19469 [PubMed]
  • Saeland Eirikur, van Vliet Sandra J., Bäckström Malin, van den Berg Venice C. M., Geijtenbeek Teunis B. H., Meijer Gerrit A., van Kooyk Yvette The C-type lectin MGL expressed by dendritic cells detects glycan changes on MUC1 in colon carcinoma Cancer immunology, immunotherapy 2007;56 (8):1225-1236 [PubMed]

2006

  • Naarding Marloes A., Dirac Annette M., Ludwig Irene S., Speijer Dave, Lindquist Susanne, Vestman Eva-Lotta, Stax Martijn J., Geijtenbeek Teunis B. H., Pollakis Georgios, Hernell Olle, Paxton William A. Bile salt-stimulated lipase from human milk binds DC-SIGN and inhibits human immunodeficiency virus type 1 transfer to CD4+ T cells Antimicrobial agents and chemotherapy 2006;50 (10):3367-3374 [PubMed]
  • van Gisbergen Klaas P. J. M. DC-SIGN mediates cellular communication of dendritic cells 2006. 212p. ISBN 9789090206172. [UvA Dissertations Online] Vrije Universiteit Amsterdam: MCBI. (Supervisor: van Kooyk Y.; Co-supervisor: Geijtenbeek T. B. H.)
  • van Vliet Sandra J., van Liempt Ellis, Geijtenbeek Teunis B. H., van Kooyk Yvette Differential regulation of C-type lectin expression on tolerogenic dendritic cell subsets Immunobiology 2006;211 (6-8):577-585 [PubMed]
  • Nabatov Alexey A., van Montfort Thijs, Geijtenbeek Teunis B. H., Pollakis Georgios, Paxton William A. Interaction of HIV-1 with dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin-expressing cells is influenced by gp120 envelope modifications associated with disease progression FEBS journal 2006;273 (21):4944-4958 [PubMed]
  • de Witte Lot, Abt Marion, Schneider-Schaulies Sibylle, van Kooyk Yvette, Geijtenbeek Teunis B. H. Measles virus targets DC-SIGN to enhance dendritic cell infection Journal of virology 2006;80 (7):3477-3486 [PubMed]
  • Oosterling Steven J., Mels Anneke K., Geijtenbeek Teunis B. H., van der Bij Gerben J., Tuk Cornelis W., Vuylsteke Ronald J. C. L. M., van Leeuwen Paul A. M., Meijer Gerrit A., Meijer Sybren, Beelen Robert H. J., van Egmond Marjolein Preoperative granulocyte/macrophage colony-stimulating factor (GM-CSF) increases hepatic dendritic cell numbers and clustering with lymphocytes in colorectal cancer patients Immunobiology 2006;211 (6-8):641-649 [PubMed]
  • van Vliet Sandra J., Gringhuis Sonja I., Geijtenbeek Teunis B. H., van Kooyk Yvette Regulation of effector T cells by antigen-presenting cells via interaction of the C-type lectin MGL with CD45 Nature immunology 2006;7 (11):1200-1208 [PubMed]
  • Koppel Estella A. The in vivo function of mSIGNR1, a DC-SIGN homologue 2006. 159p. ISBN 9789086590056. [UvA Dissertations Online] Vrije Universiteit Amsterdam: MCBI. (Supervisor: van Kooyk Y.; Co-supervisor: Geijtenbeek T. B. H.)
  • van Kooyk Yvette, Geijtenbeek Teunis B. H. Toll-like receptors keep antigen sorting on the right track Immunity 2006;25 (4):525-527 [PubMed]
  • Ludwig Irene S., Geijtenbeek Teunis B. H., van Kooyk Yvette Two way communication between neutrophils and dendritic cells Current opinion in pharmacology 2006;6 (4):408-413 [PubMed]
  • Lekkerkerker Annemarie N., van Kooyk Yvette, Geijtenbeek Teunis B. H. Viral piracy: HIV-1 targets dendritic cells for transmission Current HIV research 2006;4 (2):169-176 [PubMed]

2005

  • van Vliet Sandra J., van Liempt Ellis, Saeland Eirikur, Aarnoudse Corlien A., Appelmelk Ben, Irimura Tatsuro, Geijtenbeek Teunis B. H., Blixt Ola, Alvarez Richard, van Die Irma, van Kooyk Yvette Carbohydrate profiling reveals a distinctive role for the C-type lectin MGL in the recognition of helminth parasites and tumor antigens by dendritic cells International immunology 2005;17 (5):661-669 [PubMed]
  • Koppel Estella A., Ludwig Irene S., Appelmelk Ben J., van Kooyk Yvette, Geijtenbeek Teunis B. H. Carbohydrate specificities of the murine DC-SIGN homologue mSIGNR1 Immunobiology 2005;210 (2-4):195-201 [PubMed]
  • van Gisbergen Klaas P. J. M., Geijtenbeek Teunis B. H., van Kooyk Yvette Close encounters of neutrophils and DCs Trends in immunology 2005;26 (12):626-631 [PubMed]
  • Koppel Estella A., Saeland Eirikur, de Cooker Désirée J. M., van Kooyk Yvette, Geijtenbeek Teunis B. H. DC-SIGN specifically recognizes Streptococcus pneumoniae serotypes 3 and 14 Immunobiology 2005;210 (2-4):203-210 [PubMed]
  • van Gisbergen Klaas P. J. M., Aarnoudse Corlien A., Meijer Gerrit A., Geijtenbeek Teunis B. H., van Kooyk Yvette Dendritic cells recognize tumor-specific glycosylation of carcinoembryonic antigen on colorectal cancer cells through dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin Cancer research 2005;65 (13):5935-5944 [PubMed]
  • Koppel Estella A., van Gisbergen Klaas P. J. M., Geijtenbeek Teunis B. H., van Kooyk Yvette Distinct functions of DC-SIGN and its homologues L-SIGN (DC-SIGNR) and mSIGNR1 in pathogen recognition and immune regulation Cellular microbiology 2005;7 (2):157-165 [PubMed]
  • van Gisbergen Klaas P. J. M., Ludwig Irene S., Geijtenbeek Teunis B. H., van Kooyk Yvette Interactions of DC-SIGN with Mac-1 and CEACAM1 regulate contact between dendritic cells and neutrophils FEBS letters 2005;579 (27):6159-6168 [PubMed]
  • Groot Fedde, Geijtenbeek Teunis B. H., Sanders Rogier W., Baldwin Christopher E., Sanchez-Hernandez Marta, Floris René, van Kooyk Yvette, de Jong Esther C., Berkhout Ben Lactoferrin prevents dendritic cell-mediated human immunodeficiency virus type 1 transmission by blocking the DC-SIGN--gp120 interaction Journal of virology 2005;79 (5):3009-3015 [PubMed]
  • Naarding Marloes A., Ludwig Irene S., Groot Fedde, Berkhout Ben, Geijtenbeek Teunis B. H., Pollakis Georgios, Paxton William A. Lewis X component in human milk binds DC-SIGN and inhibits HIV-1 transfer to CD4(+) T lymphocytes Journal of clinical investigation 2005;115 (11):3256-3264 [PubMed]
  • van Gisbergen Klaas P. J. M., Paessens Lutz C., Geijtenbeek Teunis B. H., van Kooyk Yvette Molecular mechanisms that set the stage for DC-T cell engagement Immunology letters 2005;97 (2):199-208 [PubMed]
  • van Gisbergen Klaas P. J. M., Sanchez-Hernandez Marta, Geijtenbeek Teunis B. H., van Kooyk Yvette Neutrophils mediate immune modulation of dendritic cells through glycosylation-dependent interactions between Mac-1 and DC-SIGN Journal of experimental medicine 2005;201 (8):1281-1292 [PubMed]
  • Koppel Estella A., Wieland Catharina W., van den Berg Venice C. M., Litjens Manja, Florquin Sandrine, van Kooyk Yvette, van der Poll Tom, Geijtenbeek Teunis B. H. Specific ICAM-3 grabbing nonintegrin-related 1 (SIGNR1) expressed by marginal zone macrophages is essential for defense against pulmonary Streptococcus pneumoniae infection European journal of immunology 2005;35 (10):2962-2969 [PubMed]

2004

  • Arrighi Jean-François, Pion Marjorie, Garcia Eduardo, Escola Jean-Michel, van Kooyk Yvette, Geijtenbeek Teunis B., Piguet Vincent DC-SIGN-mediated infectious synapse formation enhances X4 HIV-1 transmission from dendritic cells to T cells Journal of experimental medicine 2004;200 (10):1279-1288 [PubMed]
  • Engering Anneke, van Vliet Sandra J., Hebeda Konnie, Jackson David G., Prevo Remko, Singh Satwinder K., Geijtenbeek Teunis B. H., van Krieken Han, van Kooyk Yvette Dynamic populations of dendritic cell-specific ICAM-3 grabbing nonintegrin-positive immature dendritic cells and liver/lymph node-specific ICAM-3 grabbing nonintegrin-positive endothelial cells in the outer zones of the paracortex of human lymph nodes American journal of pathology 2004;164 (5):1587-1595 [PubMed]
  • Ludwig Irene S., Lekkerkerker Annemarie N., Depla Erik, Bosman Fons, Musters René J. P., Depraetere Stany, van Kooyk Yvette, Geijtenbeek Teunis B. H. Hepatitis C virus targets DC-SIGN and L-SIGN to escape lysosomal degradation Journal of virology 2004;78 (15):8322-8332 [PubMed]
  • Koppel Estella A., Ludwig Irene S., Hernandez Marta Sanchez, Lowary Todd L., Gadikota Rajendrakumar R., Tuzikov Alexander B., Vandenbroucke-Grauls Christina M. J. E., van Kooyk Yvette, Appelmelk Ben J., Geijtenbeek Teunis B. H. Identification of the mycobacterial carbohydrate structure that binds the C-type lectins DC-SIGN, L-SIGN and SIGNR1 Immunobiology 2004;209 (1-2):117-127 [PubMed]
  • Arrighi Jean-François, Pion Marjorie, Wiznerowicz Maciej, Geijtenbeek Teunis B., Garcia Eduardo, Abraham Shahnaz, Leuba Florence, Dutoit Valérie, Ducrey-Rundquist Odile, van Kooyk Yvette, Trono Didier, Piguet Vincent Lentivirus-mediated RNA interference of DC-SIGN expression inhibits human immunodeficiency virus transmission from dendritic cells to T cells Journal of virology 2004;78 (20):10848-10855 [PubMed]
  • van Liempt Ellis, Imberty Anne, Bank Christine M. C., van Vliet Sandra J., van Kooyk Yvette, Geijtenbeek Teunis B. H., van Die Irma Molecular basis of the differences in binding properties of the highly related C-type lectins DC-SIGN and L-SIGN to Lewis X trisaccharide and Schistosoma mansoni egg antigens Journal of biological chemistry 2004;279 (32):33161-33167 [PubMed]
  • Lekkerkerker Annemarie N., van Kooyk Yvette, Geijtenbeek Teunis B. H. Mucosal-targeted AIDS vaccines: the next generation? Trends in microbiology 2004;12 (10):447-450 [PubMed]
  • van Kooyk Yvette, Engering Anneke, Lekkerkerker Annemarie N., Ludwig Irene S., Geijtenbeek Teunis B. H. Pathogens use carbohydrates to escape immunity induced by dendritic cells Current opinion in immunology 2004;16 (4):488-493 [PubMed]
  • Lekkerkerker Annemarie N., Ludwig Irene S., van Vliet Sandra J., van Kooyk Yvette, Geijtenbeek Teunis B. H. Potency of HIV-1 envelope glycoprotein gp120 antibodies to inhibit the interaction of DC-SIGN with HIV-1 gp120 Virology 2004;329 (2):465-476 [PubMed]
  • Geijtenbeek Teunis B. H., van Vliet Sandra J., Engering Anneke, 't Hart Bert A., van Kooyk Yvette Self- and nonself-recognition by C-type lectins on dendritic cells Annual review of immunology 2004;22:33-54 [PubMed]

2003

  • van Kooyk Yvette, Appelmelk Ben, Geijtenbeek Teunis B. H. A fatal attraction: Mycobacterium tuberculosis and HIV-1 target DC-SIGN to escape immune surveillance Trends in molecular medicine 2003;9 (4):153-159 [PubMed]
  • Appelmelk Ben J., van Die Irma, van Vliet Sandra J., Vandenbroucke-Grauls Christina M. J. E., Geijtenbeek Teunis B. H., van Kooyk Yvette Cutting edge: carbohydrate profiling identifies new pathogens that interact with dendritic cell-specific ICAM-3-grabbing nonintegrin on dendritic cells Journal of immunology (Baltimore, Md. 2003;170 (4):1635-1639 [PubMed]
  • Geijtenbeek T. B. H., van Kooyk Y. DC-SIGN: a novel HIV receptor on DCs that mediates HIV-1 transmission Current topics in microbiology and immunology 2003;276:31-54 [PubMed]
  • van Kooyk Yvette, Geijtenbeek Teunis B. H. DC-SIGN: escape mechanism for pathogens Nature reviews. Immunology 2003;3 (9):697-709 [PubMed]
  • Geijtenbeek Teunis B. H., van Vliet Sandra J., Koppel Estella A., Sanchez-Hernandez Marta, Vandenbroucke-Grauls Christine M. J. E., Appelmelk Ben, van Kooyk Yvette Mycobacteria target DC-SIGN to suppress dendritic cell function Journal of experimental medicine 2003;197 (1):7-17 [PubMed]
  • Geijtenbeek Teunis B. H., van Kooyk Yvette Pathogens target DC-SIGN to influence their fate DC-SIGN functions as a pathogen receptor with broad specificity APMIS 2003;111 (7-8):698-714 [PubMed]
  • Stuyt Rogier J. L., Netea Mihai G., Geijtenbeek Teunis B. H., Kullberg Bart Jan, Dinarello Charles A., van der Meer Jos W. M. Selective regulation of intercellular adhesion molecule-1 expression by interleukin-18 and interleukin-12 on human monocytes Immunology 2003;110 (3):329-334 [PubMed]
  • van Die Irma, van Vliet Sandra J., Nyame A. Kwame, Cummings Richard D., Bank Christine M. C., Appelmelk Ben, Geijtenbeek Teunis B. H., van Kooyk Yvette The dendritic cell-specific C-type lectin DC-SIGN is a receptor for Schistosoma mansoni egg antigens and recognizes the glycan antigen Lewis x Glycobiology 2003;13 (6):471-478 [PubMed]
  • Kämmerer Ulrike, Eggert Andreas O., Kapp Michaela, McLellan Alexander D., Geijtenbeek Teunis B. H., Dietl Johannes, van Kooyk Yvette, Kämpgen Eckhart Unique appearance of proliferating antigen-presenting cells expressing DC-SIGN (CD209) in the decidua of early human pregnancy American journal of pathology 2003;162 (3):887-896 [PubMed]

2002

  • van Kooyk Yvette, Geijtenbeek Teunis B. H. A novel adhesion pathway that regulates dendritic cell trafficking and T cell interactions Immunological reviews 2002;186:47-56 [PubMed]
  • Geijtenbeek Teunis B. H., Engering Anneke, van Kooyk Yvette DC-SIGN, a C-type lectin on dendritic cells that unveils many aspects of dendritic cell biology Journal of leukocyte biology 2002;71 (6):921-931 [PubMed]
  • Geijtenbeek Teunis B. H., van Duijnhoven Gerard C. F., van Vliet Sandra J., Krieger Elmar, Vriend Gert, Figdor Carl G., van Kooyk Yvette Identification of different binding sites in the dendritic cell-specific receptor DC-SIGN for intercellular adhesion molecule 3 and HIV-1 Journal of biological chemistry 2002;277 (13):11314-11320 [PubMed]
  • Engering Anneke, Geijtenbeek Teunis B. H., van Kooyk Yvette Immune escape through C-type lectins on dendritic cells Trends in immunology 2002;23 (10):480-485 [PubMed]
  • Smits Hermelijn H., de Jong Esther C., Schuitemaker Joost H. N., Geijtenbeek Theo B. H., van Kooyk Yvette, Kapsenberg Martien L., Wierenga Eddy A. Intercellular adhesion molecule-1/LFA-1 ligation favors human Th1 development Journal of immunology (Baltimore, Md. 2002;168 (4):1710-1716 [PubMed]
  • Geijtenbeek Teunis B. H., Groot Peter C., Nolte Martijn A., van Vliet Sandra J., Gangaram-Panday Shanti T., van Duijnhoven Gerard C. F., Kraal Georg, van Oosterhout Antoon J. M., van Kooyk Yvette Marginal zone macrophages express a murine homologue of DC-SIGN that captures blood-borne antigens in vivo Blood 2002;100 (8):2908-2916 [PubMed]
  • Engering Anneke, van Vliet Sandra J., Geijtenbeek Teunis B. H., van Kooyk Yvette Subset of DC-SIGN(+) dendritic cells in human blood transmits HIV-1 to T lymphocytes Blood 2002;100 (5):1780-1786 [PubMed]
  • Engering Anneke, Geijtenbeek Teunis B. H., van Vliet Sandra J., Wijers Mietske, van Liempt Ellis, Demaurex Nicolas, Lanzavecchia Antonio, Fransen Jack, Figdor Carl G., Piguet Vincent, van Kooyk Yvette The dendritic cell-specific adhesion receptor DC-SIGN internalizes antigen for presentation to T cells Journal of immunology (Baltimore, Md. 2002;168 (5):2118-2126 [PubMed]

2001

  • Bashirova A. A., Geijtenbeek T. B., van Duijnhoven G. C., van Vliet S. J., Eilering J. B., Martin M. P., Wu L., Martin T. D., Viebig N., Knolle P. A., KewalRamani V. N., van Kooyk Y., Carrington M. A dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin (DC-SIGN)-related protein is highly expressed on human liver sinusoidal endothelial cells and promotes HIV-1 infection Journal of experimental medicine 2001;193 (6):671-678 [PubMed]
  • Geijtenbeek T. B., van Vliet S. J., van Duijnhoven G. C., Figdor C. G., van Kooyk Y. DC-SIGN, a dentritic cell-specific HIV-1 receptor present in placenta that infects T cells in trans-a review Placenta 2001;22 (Suppl. A):S19-S23 [PubMed]
  • Bleijs D. A., Geijtenbeek T. B., Figdor C. G., van Kooyk Y. DC-SIGN and LFA-1: a battle for ligand Trends in immunology 2001;22 (8):457-463 [PubMed]
  • Geijtenbeek T. B., Koopman G., van Duijnhoven G. C., van Vliet S. J., van Schijndel A. C., Engering A., Heeney J. L., van Kooyk Y. Rhesus macaque and chimpanzee DC-SIGN act as HIV/SIV gp120 trans-receptors, similar to human DC-SIGN Immunology letters 2001;79 (1-2):101-107 [PubMed]

2000

  • Geijtenbeek T. B., Kwon D. S., Torensma R., van Vliet S. J., van Duijnhoven G. C., Middel J., Cornelissen I. L., Nottet H. S., KewalRamani V. N., Littman D. R., Figdor C. G., van Kooyk Y. DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cells Cell 2000;100 (5):587-597 [PubMed]
  • Geijtenbeek T. B., Krooshoop D. J., Bleijs D. A., van Vliet S. J., van Duijnhoven G. C., Grabovsky V., Alon R., Figdor C. G., van Kooyk Y. DC-SIGN-ICAM-2 interaction mediates dendritic cell trafficking Nature immunology 2000;1 (4):353-357 [PubMed]
  • Geijtenbeek T. B., Torensma R., van Vliet S. J., van Duijnhoven G. C., Adema G. J., van Kooyk Y., Figdor C. G. Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses Cell 2000;100 (5):575-585 [PubMed]
  • Wanten G. J., Geijtenbeek T. B., Raymakers R. A., van Kooyk Y., Roos D., Jansen J. B., Naber A. H. Medium-chain, triglyceride-containing lipid emulsions increase human neutrophil beta2 integrin expression, adhesion, and degranulation JPEN. Journal of parenteral and enteral nutrition 2000;24 (4):228-233 [PubMed]

1999

  • Geijtenbeek T. B., van Kooyk Y., van Vliet S. J., Renes M. H., Raymakers R. A., Figdor C. G. High frequency of adhesion defects in B-lineage acute lymphoblastic leukemia Blood 1999;94 (2):754-764 [PubMed]
  • de Bont N., Geijtenbeek T. B., Netea M. G., Smilde T. J., Demacker P. N., Figdor C. G., van der Meer J. W., Stalenhoef A. F. Integrin mediated adhesion of mononuclear cells from patients with familial hypercholesterolemia European journal of clinical investigation 1999;29 (9):749-757 [PubMed]
  • Snoek G. T., Berrie C. P., Geijtenbeek T. B., van der Helm H. A., Cadeé J. A., Iurisci C., Corda D., Wirtz K. W. Overexpression of phosphatidylinositol transfer protein alpha in NIH3T3 cells activates a phospholipase A Journal of biological chemistry 1999;274 (50):35393-35399 [PubMed]

1996

  • Geijtenbeek T. B., Smith A. J., Borst P., Wirtz K. W. cDNA cloning and tissue-specific expression of the phosphatidylcholine transfer protein gene Biochemical journal 1996;316 (1):49-55 [PubMed]
  • Geijtenbeek T. B., Westerman J., Heerma W., Wirtz K. W. Phosphatidylcholine transfer protein from bovine liver contains highly unsaturated phosphatidylcholine species FEBS letters 1996;391 (3):333-335 [PubMed]

1992

  • Hoffmann R. A., Geijtenbeek T., Kamerling J. P., Vliegenthart J. F. 1H-N.m.r. study of enzymically generated wheat-endosperm arabinoxylan oligosaccharides: structures of hepta- to tetradeca-saccharides containing two or three branched xylose residues Carbohydrate research 1992;223:19-44 [PubMed]
  • Ossendorp B. C., Geijtenbeek T. B., Wirtz K. W. The precursor form of the rat liver non-specific lipid-transfer protein, expressed in Escherichia coli, has lipid transfer activity FEBS letters 1992;296 (2):179-183 [PubMed]