R.E. Jonkers MD PhD publications

2021

• Sieswerda Elske, de Boer Mark G. J., Bonten Marc M. J., Boersma Wim G., Jonkers René E., Aleva Roel M., Kullberg Bart-Jan, Schouten Jeroen A., van de Garde Ewoudt M. W., Verheij Theo J., van der Eerden Menno M., Prins Jan M., Wiersinga W. Joost Recommendations for antibacterial therapy in adults with COVID-19 – an evidence based guideline Clinical microbiology and infection 2021;27 (1):61-66 [PubMed]

2020

• van Lier Yannouck F., de Bree Godelieve J., Jonkers René E., Roelofs Joris J. T. H., ten Berge Ineke J. M., Rutten Caroline E., Nur Erfan, Kuijpers Taco W., Hazenberg Mette D., Zeerleder Sacha S. Allogeneic hematopoietic cell transplantation in the management of GATA2 deficiency and pulmonary alveolar proteinosis Clinical immunology (Orlando, Fla.) 2020;218 [PubMed]
• van der Bent S. A. S., Engel M. J. C., Nossent E. J., Jonkers R. E., Wolkerstorfer A., Rustemeyer T. Tattoos and self-reported adverse events in sarcoidosis patients Journal of the European Academy of Dermatology and Venereology 2020;34 (4):e167-e169 [PubMed]

2019

• Wijmans Lizzy, Bonta Peter I., Rocha-Pinto Rita, de Bruin Daniel M., Brinkman Paul, Jonkers René E., Roelofs Joris J. T. H., Poletti Venerino, Hetzel J. rgen, Annema Jouke T. Confocal Laser Endomicroscopy as a Guidance Tool for Transbronchial Lung Cryobiopsies in Interstitial Lung Disorder Respiration; international review of thoracic diseases 2019;97 (3):259-263 [PubMed]
• van Velzen P., Brinkman P., Knobel H. H., van den Berg J. W. K., Jonkers R. E., Loijmans R. J., Prins J. M., Sterk P. J. Exhaled Breath Profiles Before, During and After Exacerbation of COPD: A Prospective Follow-Up Study COPD 2019;16 (5-6):330-337 [PubMed]

2018

• Jonkers René E. Een afwijkende thoraxfoto Nederlands tijdschrift voor geneeskunde 2018;162 [PubMed]
• Wiersinga W. J., Bonten M. J., Boersma W. G., Jonkers R. E., Aleva R. M., Kullberg B. J., Schouten J. A., Degener J. E., van de Garde E. M. W., Verheij T. J., Sachs A. P. E., Prins J. M. Management of community-acquired pneumonia in adults: 2016 guideline update from the Dutch Working Party on Antibiotic Policy (SWAB) and Dutch Association of Chest Physicians (NVALT) Netherlands journal of medicine 2018;76 (1):4-13 [PubMed]
• Lim J., van Royen-Kerkhof A., Jonkers R. E., Starink M. V., Voskuyl A. E., van der Kooi A. J. Myositis is meer dan een spierziekte Nederlands tijdschrift voor geneeskunde 2018;162:D2312 [PubMed]
• Wijmans Lizzy, de Bruin Daniel M., Bonta Peter I., Jonkers Rene E., Poletti Venerino, Annema Jouke T. Optical Coherence Tomography: A Valuable Novel Tool for Assessing the Alveolar Compartment in Interstitial Lung Disease? American journal of respiratory and critical care medicine 2018;197 (9):1231-1232 [PubMed]
• Oja A. E., Piet B., Helbig C., Stark R., van der Zwan D., Blaauwgeers H., Remmerswaal E. B. M., Amsen D., Jonkers R. E., Moerland P. D., Nolte M. A., van Lier R. A. W., Hombrink P. Trigger-happy resident memory CD4(+) T cells inhabit the human lungs Mucosal immunology 2018;11:654-667 [PubMed]

2017

• van Velzen Patricia, ter Riet Gerben, Bresser Paul, Baars Jeroen J., van den Berg Bob T. J., van den Berg Jan W. K., Brinkman Paul, Dagelet Jennece W. F., Daniels Johannes M. A., Groeneveld-Tjiong Dewi R. G. L., Jonkers René E., van Kan Coen, Krouwels Frans H., Pool Karin, Rudolphus Arjan, Sterk Peter J., Prins Jan M. Doxycycline for outpatient-treated acute exacerbations of COPD: a randomised double-blind placebo-controlled trial lancet. Respiratory medicine 2017;5 (6):492-499 [PubMed]
• Hombrink Pleun, Helbig Christina, Backer Ronald A., Piet Berber, Oja Anna E., Stark Regina, Brasser Giso, Jongejan Aldo, Jonkers René E., Nota Benjamin, Basak Onur, Clevers Hans C., Moerland Perry D., Amsen Derk, van Lier René A. W. Programs for the persistence, vigilance and control of human CD8(+) lung-resident memory T cells (vol 17, pg 1467, 2016) Nature immunology 2017;18 (2):246 [PubMed]
• Jolink Hetty, de Boer Renate, Hombrink Pleun, Jonkers René E., van Dissel Jaap T., Falkenburg J. H. Frederik, Heemskerk Mirjam H. M. Pulmonary immune responses against Aspergillus fumigatus are characterized by high frequencies of IL-17 producing T-cells Journal of infection 2017;74 (1):81-88 [PubMed]
• de Kruif Martijn D., Gerritsen Marije G., van Haren Eric H., Bel Elisabeth H., Jonkers Rene E. Timing of broncho-alveolar lavage for galactomannan testing in hematological oncology patients clinical respiratory journal 2017;11 (4):534-536 [PubMed]

2016

• Bal Suzanne M., Bernink Jochem H., Nagasawa Maho, Groot Jelle, Shikhagaie Medya M., Golebski Kornel, van Drunen Cornelis M., Lutter Rene, Jonkers Rene E., Hombrink Pleun, Bruchard Melanie, Villaudy Julien, Munneke J. Marius, Fokkens Wytske, Erjefält Jonas S., Spits Hergen, Ros Xavier Romero IL-1β, IL-4 and IL-12 control the fate of group 2 innate lymphoid cells in human airway inflammation in the lungs Nature immunology 2016;17 (6):636-645 [PubMed]
• Hombrink Pleun, Helbig Christina, Backer Ronald A., Piet Berber, Oja Anna E., Stark Regina, Brasser Giso, Jongejan Aldo, Jonkers René E., Nota Benjamin, Basak Onur, Clevers Hans C., Moerland Perry D., Amsen Derk, van Lier René A. W. Programs for the persistence, vigilance and control of human CD8(+) lung-resident memory T cells Nature immunology 2016;17 (12):1467-1478 [PubMed]
• Peters Anna L., van Hezel Maike E., Cortjens Bart, Tuip-de Boer Anita M., van Bruggen Robin, de Korte Dirk, Jonkers René E., Bonta Peter I., Zeerleder Sacha S., Lutter Rene, Juffermans Nicole P., Vlaar Alexander P. J. Transfusion of 35-Day Stored RBCs in the Presence of Endotoxemia Does Not Result in Lung Injury in Humans Critical care medicine 2016;44 (6):e412-e419 [PubMed]

2015

• Postma Douwe F., van Werkhoven Cornelis H., van Elden Leontine J. R., Thijsen Steven F. T., Hoepelman Andy I. M., Kluytmans Jan A. J. W., Boersma Wim G., Compaijen Clara J., van der Wall Eva, Prins Jan M., Oosterheert Jan J., Bonten Marc J. M., Postma D. F., van Werkhoven C. H., van Berkhout F. Teding, Hoepelman A. I. M., Oosterheert J. J., Bonten M. J. M., Thijsen S. F. T., Sankatsing S. U. C., van Elden L. J. R., Kluytmans J. A. J. W., Aerts J. G. J. V., Boersma W. G., Compaijen C. J., Soetekouw R., Veenhoven R. H., van der Wall E., van der Lee I., Jonkers R. E. Antibiotic Treatment Strategies for Community-Acquired Pneumonia in Adults New England journal of medicine 2015;372 (14):1312-1323 [PubMed]

2014

• van de Garde Martijn D. B., Martinez Fernando O., Melgert Barbro N., Hylkema Machteld N., Jonkers René E., Hamann Jörg Chronic exposure to glucocorticoids shapes gene expression and modulates innate and adaptive activation pathways in macrophages with distinct changes in leukocyte attraction Journal of immunology (Baltimore, Md. 2014;192 (3):1196-1208 [PubMed]
• Baas Marije C., Struijk Geertrude H., Moes Dirk-Jan A. R., van den Berk Inge A. H., Jonkers René E., de Fijter Johan W., van der Heide Jaap J. Homan, van Dijk Marja, ten Berge Ineke J. M., Bemelman Frederike J. Interstitial pneumonitis caused by everolimus: a case-cohort study in renal transplant recipients Transplant international 2014;27 (5):428-436 [PubMed]
• Heijmen R., Fattori R., Thompson M., Dai-Do D., Eggebrecht H., Degrieck I., Nienaber C., Cheshire N., Cao P., Rylski B., Roos H., Gasparini D., Ros Die E., Garzon G., Kam S., Deckers S., Jonkers R. Mid-term Outcomes and Aortic Remodelling After Thoracic Endovascular Repair for Acute, Subacute, and Chronic Aortic Dissection: The VIRTUE Registry European journal of vascular and endovascular surgery 2014;48 (4):363-371 [PubMed]

2013

• Dragonieri Silvano, Brinkman Paul, Mouw Evert, Zwinderman Aeilko H., Carratú Pierluigi, Resta Onofrio, Sterk Peter J., Jonkers Rene E. An electronic nose discriminates exhaled breath of patients with untreated pulmonary sarcoidosis from controls Respiratory medicine 2013;107 (7):1073-1078 [PubMed]
• van der Sluijs Koenraad F., van de Pol Marianne A., Kulik Wim, Dijkhuis Annemiek, Smids Barbara S., van Eijk Hetty W., Karlas Jos A., Molenkamp Richard, Wolthers Katja C., Johnston Sebastian L., van der Zee Jaring S., Sterk Peter J., Lutter René, Berger Marieke, Fens Niki, Yick David, Wagener Ariane H., Amelink Marijke, Reesink Herre J., Bresser Paul, Kunst Peter W. A., Venekamp Lisette N., Majoor Christof J., van Steenwijk Reindert P., Jonkers René E. Systemic tryptophan and kynurenine catabolite levels relate to severity of rhinovirus-induced asthma exacerbation: a prospective study with a parallel-group design Thorax 2013;68 (12):1122-1130 [PubMed]

2012

• Havenith Simone H. C., Yong Si La, Henson Sian M., Piet Berber, Idu Mirza M., Koch Sven D., Jonkers René E., Kragten Natasja A. M., Akbar Arne N., van Lier René A. W., ten Berge Ineke J. M. Analysis of stem-cell-like properties of human CD161(++)IL-18R alpha(+) memory CD8(+) T cells International immunology 2012;24 (10):625-636 [PubMed]
• Wiersinga W. J., Bonten M. J., Boersma W. G., Jonkers R. E., Aleva R. M., Kullberg B. J., Schouten J. A., Degener J. E., Janknegt R., Verheij T. J., Sachs A. P. E., Prins J. M. SWAB/NVALT (Dutch Working Party on Antibiotic Policy and Dutch Association of Chest Physicians) Guidelines on the Management of Community-Acquired Pneumonia in Adults Netherlands journal of medicine 2012;70 (2):90-101 [PubMed]

2011

• Piet Berber, de Bree Godelieve J., Smids-Dierdorp Barbara S., van der Loos Chris M., Remmerswaal Ester B. M., von der Thüsen Jan H., van Haarst Jan M. W., Eerenberg Jan P., ten Brinke Anja, van der Bij Wim, Timens Wim, van Lier René A. W., Jonkers René E. CD8(+) T cells with an intraepithelial phenotype upregulate cytotoxic function upon influenza infection in human lung Journal of clinical investigation 2011;121 (6):2254-2263 [PubMed]
• Piet Berber Lymphocytes in the frontline. Local human T cells facing the challenges of the lung environment 2011. 186p. ISBN 9789461820426. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van Lier R. A. W.; Co-supervisor: Jonkers R. E.)

2010

• Peelen Linda, Wells Athol U., Prijs Maurice, Blumenthal Judith P., van Steenwijk Reindert P., Jonkers René E., Peek Niels, Bresser Paul Fibrotic idiopathic interstitial pneumonias: Mortality is linked to a decline in gas transfer Respirology (Carlton, Vic.) 2010;15 (8):1233-1243 [PubMed]
• Boot Rolf G., Hollak Carla E. M., Verhoek Marri, Alberts C., Jonkers René E., Aerts Johannes M. Plasma chitotriosidase and CCL18 as surrogate markers for granulomatous macrophages in sarcoidosis Clinica chimica acta; international journal of clinical chemistry 2010;411 (1-2):31-36 [PubMed]
• Aalbers René, Boorsma Martin, van der Woude Hanneke J., Jonkers René E. Protective effect of budesonide/formoterol compared with formoterol, salbutamol and placebo on repeated provocations with inhaled AMP in patients with asthma: a randomised, double-blind, cross-over study Respiratory research 2010;11:66 [PubMed]

2008

• Boorsma Martin Inflammation in chronic obstructive pulmonary disease: its assessment and the effects of corticosteroids 2008. 215p. ISBN 9789090235998. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Jansen H. M.; Co-supervisors: Jonkers R. E., Lutter R.)
• Boorsma M., Lutter R., van de Pol M. A., Out T. A., Jansen H. M., Jonkers R. E. Long-Term Effects of Budesonide on Inflammatory Status in COPD COPD 2008;5 (2):97-104 [PubMed]
• van Veen Anneke, Weller Frank R., Wierenga Eddy A., Jansen Henk M., Jonkers René E. The influence of the AA 16 beta 2-adrenoceptor polymorphism on systemic and airway responses in asthma Pulmonary pharmacology & therapeutics 2008;21 (1):73-78 [PubMed]

2007

• de Bree Godelieve J., Daniels Hans, Schilfgaarde Muriel van, Jansen Henk M., Out Theo A., van Lier Rene A. W., Jonkers Rene E. Characterization of CD4+ memory T cell responses directed against common respiratory pathogens in peripheral blood and lung Journal of infectious diseases 2007;195 (11):1718-1725 [PubMed]
• Boorsma Martin, Lutter René, van de Pol Marianne A., Out Theo A., Jansen Henk M., Jonkers René E. Repeatability of inflammatory parameters in induced sputum of COPD patients COPD 2007;4 (4):321-329 [PubMed]
• Elkhuizen Sylvia G., Burger Matthe P. M., Jonkers Rene E., Limburg Martien, Klazinga Niek, Bakker Piet J. M. Using business process redesign to reduce wait times at a university hospital in the Netherlands Joint Commission journal on quality and patient safety / Joint Commission Resources 2007;33 (6):332-341 [PubMed]

2006

• van Veen Anneke, Wierenga Eddy A., Westland Robert, Weller Frank R., Hart Guus A. M., Jansen Henk M., Jonkers René E. Limited beta2-adrenoceptor haplotypes display different agonist mediated airway responses in asthmatics Respiratory research 2006;7:19 [PubMed]
• Jonkers René E., Bantje Theo A., Aalbers René Onset of relief of dyspnoea with budesonide/formoterol or salbutamol following methacholine-induced severe bronchoconstriction in adults with asthma: a double-blind, placebo-controlled study Respiratory research 2006;7:141 [PubMed]
• de Bree G. J. Phenotype and function of human T cells specific for respiratory viruses 2006. 176p. ISBN 9789090203065. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Jansen H. M., van Lier R. A. W.; Co-supervisors: Out T. A., Jonkers R. E.)
• van Veen A. Variability in genetics and beta2-adrenoreceptor mediated clinical responses in bronchial asthma 2006. 111p. ISBN 9789090208084. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Jansen H. M.; Co-supervisor: Jonkers R. E.)

2005

• Jonkers R. E., van der Zee J. S. Anti-IgE and other new immunomodulation-based therapies for allergic asthma Netherlands journal of medicine 2005;63 (4):121-128 [PubMed]
• Schouten J. A., Prins J. M., Bonten M., Degener J. E., Janknegt R., Hollander J. M. R., Jonkers R., Wijnands W., Verheij T., Sachs A., Kullberg B. J. Optimaliseren van het antibioticabeleid in Nederland. VIII. Herziene SWAB-richtlijnen voor antimicrobiële therapie bij thuis opgelopen pneumonie Nederlands tijdschrift voor geneeskunde 2005;149 (45):2495-2500 [PubMed]
• de Bree Godelieve J., Heidema Jojanneke, van Leeuwen Ester M. M., van Bleek Grada M., Jonkers René E., Jansen Henk M., van Lier René A. W., Out Theo A. Respiratory syncytial virus-specific CD8+ memory T cell responses in elderly persons Journal of infectious diseases 2005;191 (10):1710-1718 [PubMed]
• Schouten J. A., Prins J. M., Bonten M. J., Degener J., Janknegt R. E., Hollander J. M. R., Jonkers R. E., Wijnands W. J., Verheij T. J., Sachs A. P. E., Kullberg B. J. Revised SWAB guidelines for antimicrobial therapy of community-acquired pneumonia Netherlands journal of medicine 2005;63 (8):323-335 [PubMed]
• de Bree Godelieve J., van Leeuwen Ester M. M., Out Theo A., Jansen Henk M., Jonkers René E., van Lier René A. W. Selective accumulation of differentiated CD8+ T cells specific for respiratory viruses in the human lung Journal of experimental medicine 2005;202 (10):1433-1442 [PubMed]
• Oud K. T. M., Bresser P., ten Berge R. J. M., Jonkers R. E. The shrinking lung syndrome in systemic lupus erythematosus: improvement with corticosteroid therapy Lupus 2005;14 (12):959-963 [PubMed]

2004

• Jonkers R. E., Lettinga K. D., Pels Rijcken T. H., Prins J. M., Roos C. M., van Delden O. M., Verbon A., Bresser P., Jansen H. M. Abnormal radiological findings and a decreased carbon monoxide transfer factor can persist long after the acute phase of Legionella pneumophila pneumonia Clinical infectious diseases 2004;38 (5):605-611 [PubMed]
• van Rietschoten J. G. I., Westland R., van den Bogaard R., Nieste-Otter M. A., van Veen A., Jonkers R. E., van der Pouw Kraan T. C. T. M., den Hartog M. T., Wierenga E. A. A novel polymorphic GATA site in the human IL-12Rbeta2 promoter region affects transcriptional activity Tissue antigens 2004;63 (6):538-546 [PubMed]
• Dongelmans Dave A., Jonkers Rene E., Schultz Marcus J. Case report: A ball valve blood clot in the airways - life-saving whole tube suction Critical care (London, England) 2004;8 (5):R289-R290 [PubMed]
• Vriend Joris W. J., Meijboom Lilian J., Nollen Gijs J., Jonkers René E., de Mol Bas A. J. M., Mulder Barbara J. M. Compression of the left main bronchus and pulmonary artery after entire aortic replacement with Dacron arterial grafts Annals of thoracic surgery 2004;78 (3):e54-e55 [PubMed]
• Westland Robert, van Veen Anneke, Jansen Henk M., Jonkers Rene E., Wierenga Eddy A. Limited impact of multiple 5' single-nucleotide polymorphisms on the transcriptional control of the human beta 2-adrenoceptor gene Immunogenetics 2004;56 (9):625-630 [PubMed]

2003

• van Veen A., Weller F. R., Wierenga E. A., Jansen H. M., Jonkers R. E. A comparison of salmeterol and formoterol in attenuating airway responses to short-acting beta(2)-agonists Pulmonary pharmacology & therapeutics 2003;16 (3):153-161 [PubMed]
• Jonkers R. E., Boersma W. G. Pneumokokkenvaccinatie van volwassenen Nederlands tijdschrift voor geneeskunde 2003;147 (10):437-441 [PubMed]

2002

• Lettinga Kamilla D., Verbon Annelies, Nieuwkerk Pythia T., Jonkers Rene E., Gersons Berthold P. R., Prins Jan M., Speelman Peter Health-related quality of life and posttraumatic stress disorder among survivors of an outbreak of Legionnaires disease Clinical infectious diseases 2002;35 (1):11-17 [PubMed]
• Jonkers R. E. Immuunmodulatie en gentherapie in opmars: nieuwe behandelingen voor astma Pharmaceutisch Weekblad 2002;137 (1):27-31
• McClain Kenneth L., Gonzalez Jorge Mario, Jonkers Rene, de Juli Emanuela, Egeler Maarten Need for a cooperative study: Pulmonary Langerhans cell histiocytosis and its management in adults Medical and pediatric oncology 2002;39 (1):35-39 [PubMed]

1998

• van den Berg B. T., Louwerse R. T., Luiken G. J., Jonkers R. E., van Boxtel C. J. Hypokalaemia in healthy volunteers after single and multiple doses of formoterol or salbutamol Clinical drug investigation 1998;15 (6):523-529 [PubMed]

1997

• Jonkers R. E., Koopmans R. P. Beta 2 adrenoceptor agonist/antagonist activity of formoterol and salmeterol Thorax 1997;52 (3):305 [PubMed]

1995

• Jonkers R. E., Koopmans R. P. Beta 2 agonist/antagonist activity of salbutamol Thorax 1995;50 (11):1227-1228 [PubMed]
• Jonkers R. E., Braat M. C., Koopmans R. P., van Boxtel C. J. Pharmacodynamic modelling of the drug-induced downregulation of a beta 2-adrenoceptor mediated response and lack of restoration of receptor function after a single high dose of prednisone European journal of clinical pharmacology 1995;49 (1-2):37-44 [PubMed]
• Koopmans R. P., Jonkers R. E., Braat M. C., van Boxtel C. J. Pharmacokinetic-pharmacodynamic modelling as applied to bronchial asthma Clinical pharmacokinetics 1995;29 (4):213-220 [PubMed]

1992

• Braat M. C., Jonkers R. E., van Boxtel C. J. Quantification of metoprolol beta 2-adrenoceptor antagonism in asthmatic patients by pharmacokinetic-pharmacodynamic modelling Pulmonary pharmacology 1992;5 (1):31-38 [PubMed]
• Braat M. C., Jonkers R. E., Bel E. H., van Boxtel C. J. Quantification of theophylline-induced eosinopenia and hypokalaemia in healthy volunteers Clinical pharmacokinetics 1992;22 (3):231-237 [PubMed]

1991

• Jonkers R. E., Koopmans R. P., Portier E. J., van Boxtel C. J. Debrisoquine phenotype and the pharmacokinetics and beta-2 receptor pharmacodynamics of metoprolol and its enantiomers Journal of pharmacology and experimental therapeutics 1991;256 (3):959-966 [PubMed]

1989

• Jonkers R., van Boxtel C. J., Koopmans R. P., Oosterhuis B. A nonsteady-state agonist antagonist interaction model using plasma potassium concentrations to quantify the beta-2 selectivity of beta blockers Journal of pharmacology and experimental therapeutics 1989;249 (1):297-302 [PubMed]

1987

• Jonkers R., van Boxtel C. J., Oosterhuis B. Beta-2-adrenoceptor-mediated hypokalemia and its abolishment by oxprenolol Clinical pharmacology and therapeutics 1987;42 (6):627-633 [PubMed]

1982

• Jonkers R. E., Oosterhuis B., ten Berge R. J., van Boxtel C. J. Analysis of 6-mercaptopurine in human plasma with a high-performance liquid chromatographic method including post-column derivatization and fluorimetric detection Journal of chromatography. A 1982;233:249-255 [PubMed]