F. Hugenholtz PhD

Research Associate
Main activities
Microbiota, Microbiology, Infectious diseases
Focus of research

The role of microbiota in both local and systemic immune function plays an important role in immunity and health. The microbiota can aid in resistance to pathogenic species, when depleted by antibiotics mice become more susceptible to a range of pathogens.
There is an increasing realization, however, that most pathogens do not act in isolation. Little is known in these infections about the onset and progression of the disease in relation to the status of gut microbiota. Monitoring gut microbiota over time and looking at the interaction of the microbial members will result in insights in disease development.

Key publications
  • Hugenholtz Floor, de Vos Willem M. Mouse models for human intestinal microbiota research: a critical evaluation Cellular and molecular life sciences 2018;75 (1):149-160 [PubMed]
All Publications
Research programmes

Prof. W.J. Wiersinga MD PhD (Translational research in infectious diseases from microbes to man)