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PhD V. de Waard

Position
Assistant Professor
Main activities
Education, Research
Specialisation
aneurysm development
Focus of research

Develop therapeutics that can reduce vessel wall degradation and thus decrease the growth (rate) of aortic aneurysms.

Key publications
  • Hibender Stijntje, Franken Romy, van Roomen Cindy, ter Braake Anique, van der Made Ingeborg, Schermer Edith E., Gunst Quinn, van den Hoff Maurice J., Lutgens Esther, Pinto Yigal M., Groenink Maarten, Zwinderman Aeilko H., Mulder Barbara J. M., de Vries Carlie J. M., de Waard Vivian Resveratrol Inhibits Aortic Root Dilatation in the Fbn1C1039G/+ Marfan Mouse Model Arteriosclerosis, thrombosis, and vascular biology 2016;36 (8):1618-1626 [PubMed]
  • Medzikovic Lejla, Schumacher Cees A., Verkerk Arie O., van Deel Elza D., Wolswinkel Rianne, van der Made Ingeborg, Bleeker Natascha, Cakici Daniella, van den Hoogenhof Maarten M. G., Meggouh Farid, Creemers Esther E., Remme Carol Ann, Baartscheer Antonius, de Winter Robbert J., de Vries Carlie J. M., Arkenbout E. Karin, de Waard Vivian Orphan nuclear receptor Nur77 affects cardiomyocyte calcium homeostasis and adverse cardiac remodelling Scientific reports 2015;5:15404 [PubMed]
  • Franken Romy, den Hartog Alexander W., Radonic Teodora, Micha Dimitra, Maugeri Alessandra, van Dijk Fleur S., Meijers-Heijboer Hanne E., Timmermans Janneke, Scholte Arthur J., van den Berg Maarten P., Groenink Maarten, Mulder Barbara J. M., Zwinderman Aeilko H., de Waard Vivian, Pals Gerard Beneficial Outcome of Losartan Therapy Depends on Type of FBN1 Mutation in Marfan Syndrome Circulation. Cardiovascular genetics 2015;8 (2):383-388 [PubMed]
  • Groenink Maarten, den Hartog Alexander W., Franken Romy, Radonic Teodora, de Waard Vivian, Timmermans Janneke, Scholte Arthur J., van den Berg Maarten P., Spijkerboer Anje M., Marquering Henk A., Zwinderman Aeilko H., Mulder Barbara J. M. Losartan reduces aortic dilatation rate in adults with Marfan syndrome: a randomized controlled trial European heart journal 2013;34 (45):3491-3500 [PubMed]
  • Marinkovic Goran, Hibender Stijntje, Hoogenboezem Mark, van Broekhoven Amber, Girigorie Arginell F., Bleeker Natascha, Hamers Anouk A. J., Stap Jan, van Buul Jaap D., de Vries Carlie J. M., de Waard Vivian Immunosuppressive drug azathioprine reduces aneurysm progression through inhibition of Rac1 and c-Jun-terminal-N-kinase in endothelial cells Arteriosclerosis, thrombosis, and vascular biology 2013;33 (10):2380-2388 [PubMed]
All Publications
Curriculum Vitae
1989-1995 Studying Medical Biology, Biology Faculty, University of Amsterdam

1996-1997 Research Scientist at Dept Vascular Biology of The Scripps Research Institute, La Jolla, CA, USA

1997-2002 PhD Student at the Medical Biochemistry Dept, AMC, University of Amsterdam

2002-2004 Post doc at the Medical Biochemistry Dept, AMC, University of Amsterdam

2004-2008 Post doc at the Div. of Biopharmaceutics, Leiden/ Amsterdam Center for Drug Research, Leiden University

2008-present Assistant Professor at the Medical Biochemistry Dept, AMC, University of Amsterdam

Research programmes

PhD V. de Waard (Understanding aortic aneurysm progression)

Prof. PhD C.J.M. de Vries (Regulation of Vascular Homeostasis and Metabolism)

Current research funding
  • Life Sciences Health TKI
  • Stichting AMC Foundation (Vrijgesteld)
  • ZonMw