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Prof. PhD D.J. Richel

Position
Full Professor
Main activities
Patient care, Research
Specialisation
internal medicin / medical oncology
Focus of research

Clinic: Phase I,II,III clinical studies in cancer patients. Focus on gastrointestinal cancers.

Clinic / laboratory:  Translational research targeted therapy , cell signaling

Laboratory: Cancer Stem cells, Hemostasis and cancer,

 

Key publications
  • Verhoeff J. J. C., Lavini C., van Linde M. E., Stalpers L. J. A., Majoie C. B. L. M., Reijneveld J. C., van Furth W. R., Richel D. J. Bevacizumab and dose-intense temozolomide in recurrent high-grade glioma Annals of oncology 2010;21 (8):1723-1727 [PubMed]
  • Vermeulen Louis, de Sousa E Melo Felipe, van der Heijden Maartje, Cameron Kate, de Jong Joan H., Borovski Tijana, Tuynman Jurriaan B., Todaro Matilde, Merz Christian, Rodermond Hans, Sprick Martin R., Kemper Kristel, Richel Dick J., Stassi Giorgio, Medema Jan Paul Wnt activity defines colon cancer stem cells and is regulated by the microenvironment Nature cell biology 2010;12 (5):468-U121 [PubMed]
  • Tol Jolien, Koopman Miriam, Cats Annemieke, Rodenburg Cees J., Creemers Geert J. M., Schrama Jolanda G., Erdkamp Frans L. G., Vos Allert H., van Groeningen Cees J., Sinnige Harm A. M., Richel Dirk J., Voest Emile E., Dijkstra Jeroen R., Vink-Börger Marianne E., Antonini Ninja F., Mol Linda, van Krieken Johan H. J. M., Dalesio Otilia, Punt Cornelis J. A. Chemotherapy, Bevacizumab, and Cetuximab in Metastatic Colorectal Cancer New England journal of medicine 2009;360 (6):563-572 [PubMed]
  • van Sluis Geerte L., Niers Tatjana M. H., Esmon Charles T., Tigchelaar Wikky, Richel Dick J., Buller Harry R., van Noorden Cornelis J. F., Spek C. Arnold Endogenous activated protein C limits cancer cell extravasation through sphingosine-1-phosphate receptor 1-mediated vascular endothelial barrier enhancement Blood 2009;114 (9):1968-1973 [PubMed]
  • Rodenhuis Sjoerd, Bontenbal Marijke, Beex Louk V. A. M., Wagstaff John, Richel Dick J., Nooij Marianne A., Voest Emile E., Hupperets Pierre, van Tinteren Harm, Peterse Hans L., TenVergert Elisabeth M., de Vries Elisabeth G. E. High-dose chemotherapy with hematopoietic stem-cell rescue for high-risk breast cancer New England journal of medicine 2003;349 (1):7-16 [PubMed]
All Publications