Publications MSc PhD A. Sridhar
- Position
- Research Associate
- Main activities
- Research
- Specialisation
- Bioengineering, in vitro modelling, organoids, virology
- Focus of research
Development of different models along the airway and gut-brain axis:
1) Gut organoids and gut epithelial cultures
2) Human airway epithelial (HAE) cultures
3) Brain organoids
4) Blood-Brain Barrier
5) Immune cell co-culture with above models
Applied for elucidating the pathogenesis of several viruses:
1) Enterovirus D68 (EV-D68)
2) Enterovirus A71 (EV-A71)
3) Parechovirus A (PeV-A1 and PeV-A3)
4) SARS-CoV-2
5) RSV
6) CMV
7) HIV
Amsterdam UMC Research Institutes
AMC departments
All publications
2020
- Roodsant Thomas, Navis Marit, Aknouch Ikrame, Renes Ingrid B., van Elburg Ruurd M., Pajkrt Dasja, Wolthers Katja C., Schultsz Constance, van der Ark Kees C. H., Sridhar Adithya, Muncan Vanesa A Human 2D Primary Organoid-Derived Epithelial Monolayer Model to Study Host-Pathogen Interaction in the Small Intestine Frontiers in cellular and infection microbiology 2020;10 [PubMed]
- Sridhar Adithya, Simmini Salvatore, Ribeiro Carla M. S., Tapparel Caroline, Evers Melvin M., Pajkrt Dasja, Wolthers Katja A Perspective on Organoids for Virology Research Viruses 2020;12 (11) [PubMed]
- Depla Josse A., Sogorb-Gonzalez Marina, Mulder Lance A., Heine Vivi M., Konstantinova Pavlina, van Deventer Sander J., Wolthers Katja C., Pajkrt Dasja, Sridhar Adithya, Evers Melvin M. Cerebral Organoids: A Human Model for AAV Capsid Selection and Therapeutic Transgene Efficacy in the Brain Molecular therapy. Methods & clinical development 2020;18:167-175 [PubMed]
- García-Rodríguez Inés, Sridhar Adithya, Pajkrt Dasja, Wolthers Katja C. Put Some Guts into It: Intestinal Organoid Models to Study Viral Infection Viruses 2020;12 (11) [PubMed]
2019
- Sridhar Adithya, Karelehto Eveliina, Brouwer Lieke, Pajkrt Dasja, Wolthers Katja C. Parechovirus A Pathogenesis and the Enigma of Genotype A-3 Viruses 2019;11 (11) [PubMed]
2018
- Karelehto Eveliina, Cristella Cosimo, Yu Xiao, Sridhar Adithya, Hulsdouw Rens, de Haan Karen, van Eijk Hetty, Koekkoek Sylvie, Pajkrt Dasja, de Jong Menno D., Wolthers Katja C. Polarized entry of human parechoviruses in the airway epithelium Frontiers in cellular and infection microbiology 2018;8 (AUG) [PubMed]
2016
- Priwitaningrum Dwi L., Blondé Jean-Baptiste G., Sridhar Adithya, van Baarlen Joop, Hennink Wim E., Storm Gert, Le Gac Séverine, Prakash Jai Tumor stroma-containing 3D spheroid arrays: A tool to study nanoparticle penetration Journal of controlled release 2016;244 (Part B):257-268 [PubMed]
2014
- Sridhar Adithya, de Boer Hans L., van den Berg Albert, Le Gac Séverine Microstamped Petri dishes for scanning electrochemical microscopy analysis of arrays of microtissues PLoS ONE 2014;9 (4):e93618 [PubMed]