A.C. van Nuenen BEng publications

2017

• van der Ree Meike H., Stelma Femke, Willemse Sophie B., Brown Anthony, Swadling Leo, van der Valk Marc, Sinnige Marjan J., van Nuenen Ad C., de Vree J. Marleen L., Klenerman Paul, Barnes Eleanor, Kootstra Neeltje A., Reesink Hendrik W. Immune responses in DAA treated chronic hepatitis C patients with and without prior RG-101 dosing Antiviral research 2017;146:139-145 [PubMed]
• van der Ree Meike H., Jansen Louis, Kruize Zita, van Nuenen Ad C., van Dort Karel A., Takkenberg R. Bart, Reesink Hendrik W., Kootstra Neeltje A. Plasma MicroRNA Levels Are Associated With Hepatitis B e Antigen Status and Treatment Response in Chronic Hepatitis B Patients Journal of infectious diseases 2017;215 (9):1421-1429 [PubMed]
• van der Ree Meike H., de Vree J. Marleen, Stelma Femke, Willemse Sophie, van der Valk Marc, Rietdijk Svend, Molenkamp Richard, Schinkel Janke, van Nuenen Ad C., Beuers Ulrich, Hadi Salah, Harbers Marten, van der Veer Eva, Liu Kai, Grundy John, Patick Amy K., Pavlicek Adam, Blem Jacqueline, Huang Michael, Grint Paul, Neben Steven, Gibson Neil W., Kootstra Neeltje A., Reesink Hendrik W. Safety, tolerability, and antiviral effect of RG-101 in patients with chronic hepatitis C: a phase 1B, double-blind, randomised controlled trial Lancet 2017;389 (10070):709-717 [PubMed]

2015

• Setiawan Laurentia C., Gijsbers Esther F., van Nuenen Adrianus C., Kootstra Neeltje A. Viral evolution in HLA-B27-restricted CTL epitopes in human immunodeficiency virus type 1-infected individuals Journal of general virology 2015;96 (8):2372-2380 [PubMed]

2014

• Gijsbers Esther F., van Nuenen Ad C., de la Peňa Alba Torrents, Bowles Emma J., Stewart-Jones Guillaume B., Schuitemaker Hanneke, Kootstra Neeltje A. Low level of HIV-1 evolution after transmission from mother to child Scientific reports 2014;4:5079 [PubMed]

2013

• Gijsbers Esther F., van Nuenen Ad C., Schuitemaker Hanneke, Kootstra Neeltje A. Gag sequence variation in a human immunodeficiency virus type 1 transmission cluster influences viral replication fitness Journal of general virology 2013;94 (2):354-359 [PubMed]
• Gijsbers Esther F., Feenstra K. Anton, van Nuenen Ad C., Navis Marjon, Heringa Jaap, Schuitemaker Hanneke, Kootstra Neeltje A. HIV-1 replication fitness of HLA-B*57/58:01 CTL escape variants is restored by the accumulation of compensatory mutations in gag PLoS ONE 2013;8 (12):e81235 [PubMed]

2010

• Bunnik Evelien M., van Gils Marit J., Lobbrecht Marilie S. D., Pisas Linaida, Nanlohy Nening M., van Baarle Debbie, van Nuenen Ad C., Hessell Ann J., Schuitemaker Hanneke Emergence of monoclonal antibody b12-resistant human immunodeficiency virus type 1 variants during natural infection in the absence of humoral or cellular immune pressure Journal of general virology 2010;91 (Part 5):1354-1364 [PubMed]
• Bunnik Evelien M., Lobbrecht Marilie S. D., van Nuenen Ad C., Schuitemaker Hanneke Escape from autologous humoral immunity of HIV-1 is not associated with a decrease in replicative capacity Virology 2010;397 (1):224-230 [PubMed]

2009

• Bunnik Evelien M., van Gils Marit J., Lobbrecht Marilie S. D., Pisas Linaida, van Nuenen Ad C., Schuitemaker Hanneke Changing sensitivity to broadly neutralizing antibodies b12, 2G12, 2F5, and 4E10 of primary subtype B human immunodeficiency virus type 1 variants in the natural course of infection Virology 2009;390 (2):348-355 [PubMed]

2008

• Bunnik Evelien M., Pisas Linaida, van Nuenen Ad C., Schuitemaker Hanneke Autologous neutralizing humoral immunity and evolution of the viral envelope in the course of subtype B human immunodeficiency virus type 1 infection Journal of virology 2008;82 (16):7932-7941 [PubMed]

2007

• Quakkelaar Esther D., Bunnik Evelien M., van Alphen Floris P. J., Boeser-Nunnink Brigitte D. M., van Nuenen Ad C., Schuitemaker Hanneke Escape of human immunodeficiency virus type 1 from broadly neutralizing antibodies is not associated with a reduction of viral replicative capacity in vitro Virology 2007;363 (2):447-453 [PubMed]
• Bunnik Evelien M., Quakkelaar Esther D., van Nuenen Ad C., Boeser-Nunnink Brigitte, Schuitemaker Hanneke Increased neutralization sensitivity of recently emerged CXCR4-using human immunodeficiency virus type 1 strains compared to coexisting CCR5-using variants from the same patient Journal of virology 2007;81 (2):525-531 [PubMed]
• Quakkelaar Esther D., van Alphen Floris P. J., Boeser-Nunnink Brigitte D. M., van Nuenen Ad C., Pantophlet Ralph, Schuitemaker Hanneke Susceptibility of recently transmitted subtype B human immunodeficiency virus type 1 variants to broadly neutralizing antibodies Journal of virology 2007;81 (16):8533-8542 [PubMed]
• Quakkelaar Esther D., Beaumont Tim, van Nuenen Ad C., van Alphen Floris P. J., Boeser-Nunnink Brigitte D. M., van 't Wout Angélique B., Schuitemaker Hanneke T cell line passage can select for pre-existing neutralization-sensitive variants from the quasispecies of primary human immunodeficiency virus type-1 isolates Virology 2007;359 (1):92-104 [PubMed]

2004

• Beaumont Tim, Quakkelaar Esther, van Nuenen Ad, Pantophlet Ralph, Schuitemaker Hanneke Increased sensitivity to CD4 binding site-directed neutralization following in vitro propagation on primary lymphocytes of a neutralization-resistant human immunodeficiency virus IIIB strain isolated from an accidentally infected laboratory worker Journal of virology 2004;78 (11):5651-5657 [PubMed]

2001

• Beaumont T., van Nuenen A., Broersen S., Blattner W. A., Lukashov V. V., Schuitemaker H. Reversal of human immunodeficiency virus type 1 IIIB to a neutralization-resistant phenotype in an accidentally infected laboratory worker with a progressive clinical course Journal of virology 2001;75 (5):2246-2252 [PubMed]

2000

• Beaumont T., Broersen S., van Nuenen A., Huisman H. G., de Roda Husman A. M., Heeney J. L., Schuitemaker H. Increased neutralization sensitivity and reduced replicative capacity of human immunodeficiency virus type 1 after short-term in vivo or in vitro passage through chimpanzees Journal of virology 2000;74 (17):7699-7707 [PubMed]