C.M. van Tiel PhD publications

2020

• Shami Annelie, Atzler Dorothee, Bosmans Laura A., Winkels Holger, Meiler Svenja, Lacy Michael, van Tiel Claudia, Ta Megens Remco, Nitz Katrin, Baardman Jeroen, Kusters Pascal, Seijkens Tom, Buerger Christina, Janjic Aleksandar, Riccardi Carlo, Edsfeldt Andreas, Monaco Claudia, Daemen Mat, de Winther Menno P. J., Nilsson Jan, Weber Christian, Gerdes Norbert, Gonçalves Isabel, Lutgens Esther Glucocorticoid-induced tumour necrosis factor receptor family-related protein (GITR) drives atherosclerosis in mice and is associated with an unstable plaque phenotype and cerebrovascular events in humans European heart journal 2020;41 (31):2938-2948 [PubMed]
• Bosch Lena, de Haan Judith J., Seijkens Tom T. P., van Tiel Claudia M., Brans Maike A. D., Pasterkamp Gerard, Lutgens Esther, de Jager Saskia C. A. The therapeutic potential of targeting CD40-TRAF6 pathway in cardiovascular Diseases International journal of cardiology 2020;300:220 [PubMed]

2019

• Bosch Lena, de Haan Judith J., Seijkens Tom T. P., van Tiel Claudia M., Brans Maike A. D., Pasterkamp Gerard, Lutgens Esther, de Jager Saskia C. A. Corrigendum to ‘Small molecule-mediated inhibition of CD40-TRAF6 reduces adverse cardiac remodelling in pressure overload induced heart failure’ [Int. J. Cardiol., Volume 279, 15 March 2019, Pages 141-144](S0167527318325531)(10.1016/j.ijcard.2018.12.076) International journal of cardiology 2019;293:297 [PubMed]
• Seijkens Tom T. P., Poels Kikkie, Meiler Svenja, van Tiel Claudia M., Kusters Pascal J. H., Reiche Myrthe, Atzler Dorothee, Winkels Holger, Tjwa Marc, Poelman Hessel, Slütter Bram, Kuiper Johan, Gijbels Marion, Kuivenhoven Jan Albert, Matic Ljubica Perisic, Paulsson-Berne Gabrielle, Hedin Ulf, Hansson G. ran K., Nicolaes Gerry A. F., Daemen Mat J. A. P., Weber Christian, Gerdes Norbert, de Winther Menno P. J., Lutgens Esther Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8 + T cell-mediated macrophage death European heart journal 2019;40 (4):372-382 [PubMed]
• Aarts Suzanne A. BM, Seijkens Tom T. P., Kusters Pascal J. H., van Tiel Claudia M., Reiche Myrthe E., den Toom Myrthe, Beckers Linda, van Roomen Cindy P. AA, de Winther Menno P. J., Kooij Gijs, Lutgens Esther Macrophage CD40 signaling drives experimental autoimmune encephalomyelitis Journal of pathology 2019;247 (4):471-480 [PubMed]
• Bosch Lena, de Haan Judith, Seijkens Tom, van Tiel Claudia, Brans Maike, Pasterkamp Gerard, Lutgens Esther, de Jager Saskia Small molecule-mediated inhibition of CD40-TRAF6 reduces adverse cardiac remodelling in pressure overload induced heart failure International journal of cardiology 2019;279:141-144 [PubMed]

2018

• Koenis Duco S., Medzikovic Lejla, Vos Mariska, Beldman Thijs J., van Loenen Pieter B., van Tiel Claudia M., Hamers Anouk A. J., Rubio Iker Otermin, de Waard Vivian, de Vries Carlie J. M. Nur77 variants solely comprising the amino-terminal domain activate hypoxia-inducible factor-1 α and affect bone marrow homeostasis in mice and humans Journal of biological chemistry 2018;293 (39):15070-15083 [PubMed]
• Seijkens Tom T. P., van Tiel Claudia M., Kusters Pascal J. H., Atzler Dorothee, Soehnlein Oliver, Zarzycka Barbara, Aarts Suzanne A. B. M., Lameijer Marnix, Gijbels Marion J., Beckers Linda, den Toom Myrthe, Slütter Bram, Kuiper Johan, Duchene Johan, Aslani Maria, Megens Remco T. A., van 't Veer Cornelis, Kooij Gijs, Schrijver Roy, Hoeksema Marten A., Boon Louis, Fay Francois, Tang Jun, Baxter Samantha, Jongejan Aldo, Moerland Perry D., Vriend Gert, Bleijlevens Boris, Fisher Edward A., Duivenvoorden Raphael, Gerdes Norbert, de Winther Menno P. J., Nicolaes Gerry A., Mulder Willem J. M., Weber Christian, Lutgens Esther Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis Journal of the American College of Cardiology 2018;71 (5):527-542 [PubMed]

2016

• Hamers Anouk A. J., Argmann Carmen, Moerland Perry D., Koenis Duco S., Marinković Goran, Sokolović Milka, de Vos Alex F., de Vries Carlie J. M., van Tiel Claudia M. Nur77-deficiency in bone marrow-derived macrophages modulates inflammatory responses, extracellular matrix homeostasis, phagocytosis and tolerance BMC genomics 2016;17 (1):162 [PubMed]

2015

• Hamers Anouk A. J., van Dam Laura, Teixeira Duarte José M., Vos Mariska, Marinković Goran, van Tiel Claudia M., Meijer Sybren L., van Stalborch Anne-Marieke, Huveneers Stephan, te Velde Anje A., de Jonge Wouter J., de Vries Carlie J. M. Deficiency of Nuclear Receptor Nur77 Aggravates Mouse Experimental Colitis by Increased NFκB Activity in Macrophages PLoS ONE 2015;10 (8):e0133598 [PubMed]
• Zarzycka Barbara, Seijkens Tom, Nabuurs Sander B., Ritschel Tina, Grommes Jochen, Soehnlein Oliver, Schrijver Roy, van Tiel Claudia M., Hackeng Tilman M., Weber Christian, Giehler Fabian, Kieser Arnd, Lutgens Esther, Vriend Gert, Nicolaes Gerry A. F. Discovery of Small Molecule CD40-TRAF6 Inhibitors Journal of chemical information and modeling 2015;55 (2):294-307 [PubMed]
• Kurakula Kondababu, Sommer Daniela, Sokolovic Milka, Moerland Perry D., Scheij Saskia, van Loenen Pieter B., Koenis Duco S., Zelcer Noam, van Tiel Claudia M., de Vries Carlie J. M. LIM-Only Protein FHL2 Is a Positive Regulator of Liver X Receptors in Smooth Muscle Cells Involved in Lipid Homeostasis Molecular and cellular biology 2015;35 (1):52-62 [PubMed]
• Kurakula Konda Babu Nur77 and FHL2: Novel players in vascular and immune disease 2015. 313p. ISBN 9789462330122. [UvA Dissertations Online] University of Amsterdam. (Supervisor: de Vries C. J. M.; Co-supervisors: van Tiel C. M., de Waard V.)
• Ruiter Matthijs S., van Tiel Claudia M., Doornbos Albert, Marinković Goran, Strang Aart C., Attevelt Nico J. M., de Waard Vivian, de Winter Robbert J., Steendam Rob, de Vries Carlie J. M. Stents Eluting 6-Mercaptopurine Reduce Neointima Formation and Inflammation while Enhancing Strut Coverage in Rabbits PLoS ONE 2015;10 (9):e0138459 [PubMed]

2014

• Silvestre-Roig Carlos, Fernández Patricia, Mansego María L., van Tiel Claudia M., Viana Rosa, Anselmi Chiara Viviani, Condorelli Gianluigi, de Winter Robbert J., Martín-Fuentes Paula, Solanas-Barca María, Civeira Fernando, Focaccio Amelia, de Vries Carlie J. M., Chaves Felipe Javier, Andrés Vicente Genetic variants in CCNB1 associated with differential gene transcription and risk of coronary in-stent restenosis Circulation. Cardiovascular genetics 2014;7 (1):59-70 [PubMed]
• Hamers Anouk A. J., Uleman Sven, van Tiel Claudia M., Kruijswijk Daniëlle, van Stalborch Anne-Marieke, Huveneers Stephan, de Vries Carlie J. M., van 't Veer Cornelis Limited role of nuclear receptor Nur77 in Escherichia coli-induced peritonitis Infection and immunity 2014;82 (1):253-264 [PubMed]
• Kurakula Kondababu, Koenis Duco S., van Tiel Claudia M., de Vries Carlie J. M. NR4A nuclear receptors are orphans but not lonesome BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 2014;1843 (11):2543-2555 [PubMed]
• Kurakula Kondababu, Vos Mariska, Otermin Rubio Iker, Marinković Goran, Buettner Reinhard, Heukamp Lukas C., Stap Jan, de Waard Vivian, van Tiel Claudia M., de Vries Carlie J. M. The LIM-only protein FHL2 reduces vascular lesion formation involving inhibition of proliferation and migration of smooth muscle cells PLoS ONE 2014;9 (4):e94931-(9 p.) [PubMed]

2012

• van Tiel Claudia M., Kurakula Kondababu, Koenis Duco S., van der Wal Erik, de Vries Carlie J. M. Dual function of Pin1 in NR4A nuclear receptor activation: Enhanced activity of NR4As and increased Nur77 protein stability BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 2012;1823 (10):1894-1904 [PubMed]
• van Tiel Claudia M., de Vries Carlie J. M. NR4All in the vessel wall Journal of steroid biochemistry and molecular biology 2012;130 (3-5):186-193 [PubMed]
• Maijenburg Marijke W., Gilissen Christian, Melief Sara M., Kleijer Marion, Weijer Kees, ten Brinke Anja, Roelofs Helene, van Tiel Claudia M., Veltman Joris A., de Vries Carlie J. M., van der Schoot C. Ellen, Voermans Carlijn Nuclear Receptors Nur77 and Nurr1 Modulate Mesenchymal Stromal Cell Migration Stem cells and development 2012;21 (2):228-238 [PubMed]

2011

• Kurakula Kondababu, van der Wal Erik, Geerts Dirk, van Tiel Claudia M., de Vries Carlie J. M. FHL2 protein is a novel co-repressor of nuclear receptor Nur77 Journal of biological chemistry 2011;286 (52):44336-44343 [PubMed]

2010

• Bonta Peter I., Pols Thijs W. H., van Tiel Claudia M., Vos Mariska, Arkenbout E. Karin, Rohlena Jakub, Koch Karel T., de Maat Moniek P. M., Tanck Michael W. T., de Winter Robbert J., Pannekoek Hans, Biessen Erik A. L., Bot Ilze, de Vries Carlie J. M. Nuclear Receptor Nurr1 Is Expressed In and Is Associated With Human Restenosis and Inhibits Vascular Lesion Formation In Mice Involving Inhibition of Smooth Muscle Cell Proliferation and Inflammation Circulation 2010;121 (18):2023-2032 [PubMed]

2009

• Kardys Isabella, van Tiel Claudia M., de Vries Carlie J. M., Pannekoek Hans, Uitterlinden André G., Hofman Albert, Witteman Jacqueline C. M., de Maat Moniek P. M. Haplotypes of the NR4A2/NURR1 Gene and Cardiovascular Disease. The Rotterdam Study Human mutation 2009;30 (3):417-423 [PubMed]
• van Tiel Claudia M., Bonta Peter I., Rittersma Saskia Z. H., Beijk Marcel A. M., Bradley Edward J., Klous Anita M., Koch Karel T., Baas Frank, Jukema J. Wouter, Pons Douwe, Sampietro M. Lourdes, Pannekoek Hans, de Winter Robbert J., de Vries Carlie J. M. p27kip1-838C>A Single Nucleotide Polymorphism Is Associated With Restenosis Risk After Coronary Stenting and Modulates p27kip1 Promoter Activity Circulation 2009;120 (8):669-676 [PubMed]
• Reuwer Anne Q., Nieuwland Rienk, Fernandez Isabelle, Goffin Vincent, van Tiel Claudia M., Schaap Marianne C. L., Berckmans René J., Kastelein John J. P., Twickler Marcel Th B. Prolactin does not affect human platelet aggregation or secretion Thrombosis and haemostasis 2009;101 (6):1119-1127 [PubMed]

2008

• van Tiel Claudia M., de Vries Carlie J. M. NR4A Nuclear Receptors in the Vessel Wallin: J. L. Junien, B. Staels, editors. Nuclear receptors as molecular targets for cardiometabolic and central nervous system diseases. Amsterdam: IOS Press; 2008. p. 75-83, ISBN 9781586038571

2007

• Pires Nuno M. M., Pols Thijs W. H., de Vries Margreet R., van Tiel Claudia M., Bonta Peter I., Vos Mariska, Arkenbout E. Karin, Pannekoek Hans, Jukema J. Wouter, Quax Paul H. A., de Vries Carlie J. M. Activation of nuclear receptor Nur77 by 6-mercaptopurine protects against neointima formation Circulation 2007;115 (4):493-500 [PubMed]
• Schenning Martijn, van Tiel Claudia M., Wirtz Karel W. A., Snoek Gerry T. The anti-apoptotic MAP kinase pathway is inhibited in NIH3T3 fibroblasts with increased expression of phosphatidylinositol transfer protein beta BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 2007;1773 (11):1664-1671 [PubMed]

2006

• Bonta Peter I., van Tiel Claudia M., Vos Mariska, Pols Thijs W. H., van Thienen Johannes V., Ferreira Valérie, Arkenbout E. Karin, Seppen Jurgen, Spek C. Arnold, van der Poll Tom, Pannekoek Hans, de Vries Carlie J. M. Nuclear receptors Nur77, Nurr1, and NOR-1 expressed in atherosclerotic lesion macrophages reduce lipid loading and inflammatory responses Arteriosclerosis, thrombosis, and vascular biology 2006;26 (10):2288-2294 [PubMed]

2004

• Schenning Martijn, van Tiel Claudia M., van Manen Daniëlle, Stam Jord C., Gadella Barend M., Wirtz Karel W. A., Snoek Gerry T. Phosphatidylinositol transfer protein alpha regulates growth and apoptosis of NIH3T3 cells: involvement of a cannabinoid 1-like receptor Journal of lipid research 2004;45 (8):1555-1564 [PubMed]
• Snoek Gerry T., van Tiel Claudia M., Egmond Maarten R. Structure-function relationships of phosphatidylinositol transfer proteins: involvement of phosphorylation sites Biochimie 2004;86 (11):857-864 [PubMed]

2002

• van Tiel Claudia M., Westerman Jan, Paasman Marten A., Hoebens Martha M., Wirtz Karel W. A., Snoek Gerry T. The Golgi localization of phosphatidylinositol transfer protein beta requires the protein kinase C-dependent phosphorylation of serine 262 and is essential for maintaining plasma membrane sphingomyelin levels Journal of biological chemistry 2002;277 (25):22447-22452 [PubMed]
• van Tiel Claudia M., Schouten Arie, Snoek Gerry T., Gros Piet, Wirtz Karel W. A. The structure of phosphatidylinositol transfer protein alpha reveals sites for phospholipid binding and membrane association with major implications for its function FEBS letters 2002;531 (1):69-73 [PubMed]

2001

• de Brouwer A. P., Bouma B., van Tiel C. M., Heerma W., Brouwers J. F., Bevers L. E., Westerman J., Roelofsen B., Wirtz K. W. The binding of phosphatidylcholine to the phosphatidylcholine transfer protein: affinity and role in folding Chemistry and physics of lipids 2001;112 (2):109-119 [PubMed]

2000

• van Tiel C. M., Luberto C., Snoek G. T., Hannun Y. A., Wirtz K. W. Rapid replenishment of sphingomyelin in the plasma membrane upon degradation by sphingomyelinase in NIH3T3 cells overexpressing the phosphatidylinositol transfer protein beta Biochemical journal 2000;346 Pt 2:537-543 [PubMed]
• van Tiel C. M., Westerman J., Paasman M., Wirtz K. W., Snoek G. T. The protein kinase C-dependent phosphorylation of serine 166 is controlled by the phospholipid species bound to the phosphatidylinositol transfer protein alpha Journal of biological chemistry 2000;275 (28):21532-21538 [PubMed]