F. Mol MD PhD publications

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Publications MD PhD F. Mol

Position
Medical Specialist
Main activities
Patient care, Research, Other
Specialisation
Gynaecologist, specialist in Reproductive Medicine
Focus of research

Current projects

Medical assisted reproduction
Home-based monitoring of ovulation to time frozen embryo transfer in IVF - the ANTARCTICA-2
Trial registration: NTR27578; toetsing online NL62924.01817; ZonMW 843002807, ‘doelmatigheidsonderzoek 2018

What is the effectiveness of IUI-OH in couples with unexplained or mild male subfertility and a poor prognosis on natural conception? - EXIUI study
Triagregistration NTR5599, toetsingonline ABR NL57383.018.16. SEENEZ project: ZonMW-grantnr 837004023

Fertility preservation
The safety of controlled ovarian stimulation in women with breast cancer: standard stimulation versus alternative stimulation protocols; the STIM-trial.
Trialregistration: Dutch Trial Register: NTR4108. Support: Virtutis Opus, Nuts Ohra

Early pregnancy
Management of ectopic pregnancy [CRD42018102160] IPD SRMA

Past projects

The freeze-all strategy in IVF: who benefits?
Trial registration: NTR5235; Support: The Netherlands Organisation for Health Research and Development (2014 ZonMW Doelmatigheid grant 837002510)

Outcome measures in IVF
Trial registration: not applicable; Support: other

Randomised controlled trial of salpingo(s)tomy versus salpingectomy for tubal pregnancy; impact on future fertility (ESEP-study)
Trial registration: Current controlled trials: ISRCTN37002267 (www.controlled-trials.com) Dutch Trial Register: NTR 115 (www.trialregister.nl)
Support: The Netherlands Organisation for Health Research and Development (ZonMW Agiko grant 920-03-328, Zonmw Clinical fellow grant 40-00703-97-05-154)

Methotrexate versus Expectant management in women with ectopic pregnancy (www.metexstudy.nl). 
Trial registration: Current controlled trials:ISRCTN48210491 (www.controlled-trials.com) Dutch Trial Register: NTR611 (www.trialregister.nl)

Support: The Netherlands Organisation for Health Research and Development (Zonmw Clinical fellow grant 40-00703-97-05-154)

Vrouwen met een buitenbaarmoederlijke zwangerschap (EUG) moeten eileidersparend geopereerd worden om hun vruchtbaarheid te behouden.
Trial registration: not applicable; Support: The Netherlands Organisation for Health Research and Development (Zonmw grant 91501009 Kennisbenutting)

 

2021

  • van Hoogenhuijze N. E., Mol F., Laven J. S. E., Groenewoud E. R., Traas M. A. F., Janssen C. A. H., Teklenburg G., de Bruin J. P., van Oppenraaij R. H. F., Maas J. W. M., Moll E., Fleischer K., van Hooff M. H. A., de Koning C. H., Cantineau A. E. P., Lambalk C. B., Verberg M., van Heusden A. M., Manger A. P., van Rumste M. M. E., van der Voet L. F., Pieterse Q. D., Visser J., Brinkhuis E. A., den Hartog J. E., Glas M. W., Klijn N. F., van der Meer S., Bandell M. L., Boxmeer J. C., van Disseldorp J., Smeenk J., van Wely M., Eijkemans M. J. C., Torrance H. L., Broekmans F. J. M. Endometrial scratching in women with one failed IVF/ICSI cycle-outcomes of a randomised controlled trial (SCRaTCH) Human reproduction (Oxford, England) 2021;36 (1):87-98 [PubMed]

2020

  • van Eekelen R., Eijkemans M. J., Mochtar M., Mol F., Mol B. W., Groen H., van Wely M. Cost-effectiveness of medically assisted reproduction or expectant management for unexplained subfertility: When to start treatment? Human reproduction (Oxford, England) 2020;35 (9):2037-2046 [PubMed]
  • Zaat T. R., de Bruin J. P., Goddijn M., Visser J., Kaaijk E. M., Lambalk C. B., Groenewoud E. R., van Wely M., Mol F. Home- or hospital-based monitoring to time frozen embryo transfer in the natural cycle? Patient-reported outcomes and experiences from the Antarctica-2 randomised controlled trial Human reproduction (Oxford, England) 2020;35 (4):866-875 [PubMed]
  • Wang Rui, van Eekelen Rik, Mochtar Monique H., Mol Femke, van Wely Madelon Treatment Strategies for Unexplained Infertility Seminars in reproductive medicine 2020;38 (1):48-54 [PubMed]

2019

  • Zaat Tjitske, Mol Femke, van Wely Madelon, Wilkinson Jack, Mastenbroek Sebastiaan Fresh versus frozen blastocyst transfer Lancet 2019;394 (10205):1227 [PubMed]
  • van den Berg Merel M. J., Hajenius Petra J., Mol Femke, Hermens Rosella P. M. G., van der Veen Fulco, Goddijn Mariette, van den Boogaard Emmy Guideline-based quality indicators for early pregnancy assessment units Reproductive biomedicine online 2019:7 [PubMed]
  • Van Eekelen R., Van Geloven N., Van Wely M., McLernon D. J., Mol F., Custers I. M., Steures P., Bhattacharya S., Mol B. W., Van Der Veen F., Eijkemans M. J. Is IUI with ovarian stimulation effective in couples with unexplained subfertility? Human reproduction (Oxford, England) 2019;34 (1):84-91 [PubMed]
  • Hendriks Saskia, van Wely Madelon, D'Hooghe Thomas M., Meissner Andreas, Mol Femke, Peeraer Karen, Repping Sjoerd, Dancet Eline A. F. The relative importance of genetic parenthood Reproductive biomedicine online 2019;39 (1):103-110 [PubMed]

2018

  • van Rijswijk Joukje, van Welie Nienke, Dreyer Kim, van Hooff Machiel H. A., de Bruin Jan Peter, Verhoeve Harold R., Mol Femke, Kleiman-Broeze Kimiko A., Traas Maaike A. F., Muijsers Guido J. J. M., Manger Arentje P., Gianotten Judith, de Koning Cornelia H., Koning Aafke M. H., Bayram Neriman, van der Ham David P., Vrouenraets Francisca P. J. M., Kalafusova Michaela, van de Laar Bob I. G., Kaijser Jeroen, van Oostwaard Miriam F., Meijer Wouter J., Broekmans Frank J. M., Valkenburg Olivier, van der Voet Lucy F., van Disseldorp Jeroen, Lambers Marieke J., Peters Henrike E., Lier Marit C. I., Lambalk Cornelis B., van Wely Madelon, Bossuyt Patrick M. M., Stoker Jaap, van der Veen Fulco, Mol Ben W. J., Mijatovic Velja The FOAM study: Is Hysterosalpingo foam sonography (HyFoSy) a cost-effective alternative for hysterosalpingography (HSG) in assessing tubal patency in subfertile women? Study protocol for a randomized controlled trial BMC Women's health 2018;18 (1) [PubMed]

2017

  • Balkenende E. M. E., Dondorp W., Ploem M. C., Lambalk C. B., Goddijn M., Mol F. A mother's gift of life: exploring the concerns and ethical aspects of fertility preservation for mother-to-daughter oocyte donation Human reproduction (Oxford, England) 2017;32 (1):2-6 [PubMed]
  • van Hoogenhuijze N. E., Torrance H. L., Mol F., Laven J. S. E., Scheenjes E., Traas M. A. F., Janssen C., Cohlen B., Teklenburg G., de Bruin J. P., van Oppenraaij R., Maas J. W. M., Moll E., Fleischer K., van Hooff M. H., de Koning C., Cantineau A., Lambalk C. B., Verberg M., Nijs M., Manger A. P., van Rumste M., van der Voet L. F., Preys-Bosman A., Visser J., Brinkhuis E., den Hartog J. E., Sluijmer A., Jansen F. W., Hermes W., Bandell M. L., Pelinck M. J., van Disseldorp J., van Wely M., Smeenk J., Pieterse Q. D., Boxmeer J. C., Groenewoud E. R., Eijkemans M. J. C., Kasius J. C., Broekmans F. J. M. Endometrial scratching in women with implantation failure after a first IVF/ICSI cycle; does it lead to a higher live birth rate? The SCRaTCH study: a randomized controlled trial (NTR 5342) BMC Women's health 2017;17 (1):47 [PubMed]
  • Braakhekke M., Mol F., Mastenbroek S., Mol B. Willem J., van der Veen F. Equipoise and the RCT Human reproduction (Oxford, England) 2017;32 (2):257-260 [PubMed]
  • Wong Kai Mee, van Wely Madelon, Mol Femke, Repping Sjoerd, Mastenbroek Sebastiaan Fresh versus frozen embryo transfers in assisted reproduction Cochrane database of systematic reviews (Online) 2017;2017 (3):CD011184 [PubMed]
  • Braakhekke Miriam Randomized controlled trials in reproductive medicine: Disclosing the caveats 2017. 159p. ISBN 9789462336896. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van der Veen F., Mol B. W. J.; Co-supervisor: Mol F.)
  • Braakhekke M., Scholten I., Mol F., Limpens J., Mol B. W., van der Veen F. Selective outcome reporting and sponsorship in randomized controlled trials in IVF and ICSI Human reproduction (Oxford, England) 2017;32 (10):2117-2122 [PubMed]

2016

  • Smit Janine G., Kasius Jenneke C., Eijkemans Marinus J. C., Koks Carolien A. M., van Golde Ronald, Nap Annemiek W., Scheffer Gabrielle J., Manger Petra A. P., Hoek Annemieke, Schoot Benedictus C., van Heusden Arne M., Kuchenbecker Walter K. H., Perquin Denise A. M., Fleischer Kathrin, Kaaijk Eugenie M., Sluijmer Alexander, Friederich Jaap, Dykgraaf Ramon H. M., van Hooff Marcel, Louwe Leonie A., Kwee Janet, de Koning Corry H., Janssen Ineke C. A. H., Mol Femke, Mol Ben W. J., Broekmans Frank J. M., Torrance Helen L. Hysteroscopy before in-vitro fertilisation (inSIGHT): a multicentre, randomised controlled trial Lancet 2016;387 (10038):2622-2629 [PubMed]
  • Smit Janine G., Kasius Jenneke C., Eijkemans Marinus J. C., Koks Carolien A. M., van Golde Ronald, Nap Annemiek W., Scheffer Gabrielle J., Manger Petra A. P., Hoek Annemieke, Schoot Benedictus C., van Heusden Arne M., Kuchenbecker Walter K. H., Perquin Denise A. M., Fleischer Kathrin, Kaaijk Eugenie M., Sluijmer Alexander, Friederich Jaap, Dykgraaf Ramon H. M., van Hooff Marcel, Louwe Leonie A., Kwee Janet, de Koning Corry H., Janssen Ineke C. A. H., Mol Femke, Mol Ben W. J., Broekmans Frank J. M., Torrance Helen L. Hysteroscopy Before In-Vitro Fertilisation (inSIGHT): A Multicentre, Randomised Controlled Trial EDITORIAL COMMENT Obstetrical & gynecological survey 2016;71 (10):600-601

2015

  • Mol F., van Mello N. M., Strandell A., Jurkovic D., Ross J. A., Yalcinkaya T. M., Barnhart K. T., Verhoeve H. R., Graziosi G. C., Koks C. A., Mol B. W., Ankum W. M., van der Veen F., Hajenius P. J., van Wely M., Janssen Ineke C. A. H., Kragt Harry, Hoek Annemieke, Trimbos-Kemper Trudy C. M., Broekmans Frank J. M., Willemsen Wim N. P., Dijkman A. B., Thurkow A. L., van Dessel H. J. H. M., van der Linden P. J. Q., Bouwmeester F. W., Oosterhuis G. J. E., van Beek J. J., Emanuel M. H., Visser H., Doornbos J. P. R., Pernet P. J. M., Friederich J., Strandell Karin, Hogström Lars, Klinte Ingmar, Pettersson F., Sabetirad Z., Nilsson K., Tegerstedt G., Platz-Christensen J. J. Cost-effectiveness of salpingotomy and salpingectomy in women with tubal pregnancy (a randomized controlled trial) Human reproduction (Oxford, England) 2015;30 (9):2038-2047 [PubMed]
  • Braakhekke M., Kamphuis E. I., Mol F., Norman R. J., Bhattacharya S., van der Veen F., Mol B. W. J. Effectiveness and safety as outcome measures in reproductive medicine Human reproduction (Oxford, England) 2015;30 (10):2249-2251 [PubMed]
  • Dahhan Taghride, Mol Femke, Kenter Gemma G., Balkenende Eva M. E., de Melker Annemieke A., van der Veen Fulco, Dancet Eline A. F., Goddijn Mariëtte Fertility preservation: a challenge for IVF-clinics European journal of obstetrics, gynecology, and reproductive biology 2015;194:78-84 [PubMed]
  • van Mello Norah M., Mol Femke, Hajenius Petra J., Ankum Willem M., Mol Ben Willem, van der Veen Fulco, van Wely Madelon Randomized comparison of health-related quality of life in women with ectopic pregnancy or pregnancy of unknown location treated with systemic methotrexate or expectant management European journal of obstetrics, gynecology, and reproductive biology 2015;192:1-5 [PubMed]

2014

  • Braakhekke M., Kamphuis E. I., van Rumste M. M., Mol F., van der Veen F., Mol B. W. How are neonatal and maternal outcomes reported in randomised controlled trials (RCTs) in reproductive medicine? Human reproduction (Oxford, England) 2014;29 (6):1211-1217 [PubMed]
  • Braakhekke Miriam, Kamphuis Esme I., Dancet Eline A., Mol Femke, van der Veen Fulco, Mol Ben W. Ongoing pregnancy qualifies best as the primary outcome measure of choice in trials in reproductive medicine: an opinion paper Fertility and sterility 2014;101 (5):1203-1204 [PubMed]
  • Mol Femke, van Mello Norah M., Strandell Annika, Strandell Karin, Jurkovic Davor, Ross Jackie, Barnhart Kurt T., Yalcinkaya Tamer M., Verhoeve Harold R., Graziosi Giuseppe C. M., Koks Carolien A. M., Klinte Ingmar, Hogström Lars, Janssen Ineke C. A. H., Kragt Harry, Hoek Annemieke, Trimbos-Kemper Trudy C. M., Broekmans Frank J. M., Willemsen Wim N. P., Ankum Willem M., Mol Ben W., van Wely Madelon, van der Veen Fulco, Hajenius Petra J., Dijkman A. B., Thurkow A. L., van Dessel H. J. H. M., van der Linden P. J. Q., Bouwmeester F. W., Oosterhuis G. J. E., van Beek J. J., Emanuel M. H., Visser H., Doornbos J. P. R., Pernet P. J. M., Friederich J., Pettersson F., Sabetirad Z., Nilsson K., Tegerstedt G., Platz-Christensen J. J. Salpingotomy versus salpingectomy in women with tubal pregnancy (ESEP study): an open-label, multicentre, randomised controlled trial Lancet 2014;383 (9927):1483-1489 [PubMed]
  • Mol Femke, Van Mello Norah M., Strandell Annika, Strandell Karin, Jurkovic Davor, Ross Jackie, Barnhart Kurt T., Yalcinkaya Tamer M., Verhoeve Harold R., Graziosi Giuseppe C.M., Koks Carolien A.M., Klinte Ingmar, Hogström Lars, Janssen Ineke C.A.H., Kragt Harry, Hoek Annemieke, Trimbos-Kemper Trudy C.M., Broekmans Frank J.M., Willemsen Wim N.P., Ankum Willem M., Mol Ben W., Van Wely Madelon, Van Der Veen Fulco, Hajenius Petra J. Salpingotomy versus salpingectomy in women with tubal pregnancy (European surgery in ectopic pregnancy study): An open-label, multicenter, randomized controlled trial Obstetrical & gynecological survey 2014;69 (9):545-547

2013

  • Van Mello Norah M., Mol Femke, Ankum Willem M., Mol Ben Willem, Van Der Veen Fulco, Hajenius Petra J. Ectopic pregnancy: How the diagnostic and therapeutic management has changed Obstetrical & gynecological survey 2013;68 (2):110-112
  • van Mello N. M., Mol F., Verhoeve H. R., van Wely M., Adriaanse A. H., Boss E. A., Dijkman A. B., Bayram N., Emanuel M. H., Friederich J., van der Leeuw-Harmsen L., Lips J. P., van Kessel M. A., Ankum W. M., van der Veen F., Mol B. W., Hajenius P. J. Methotrexate or expectant management in women with an ectopic pregnancy or pregnancy of unknown location and low serum hCG concentrations? A randomized comparison Human reproduction (Oxford, England) 2013;28 (1):60-67 [PubMed]
  • Mol Femke Surgical management of tubal pregnancy 2013. 183p. ISBN 9789461823410. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van der Veen F., Mol B. W. J.; Co-supervisors: Hajenius P. J., Ankum W. M.)

2012

  • van Mello N. M., Mol F., Opmeer B. C., Ankum W. M., Barnhart K., Coomarasamy A., Mol B. W., van der Veen F., Hajenius P. J. Diagnostic value of serum hCG on the outcome of pregnancy of unknown location: a systematic review and meta-analysis Human reproduction update 2012;18 (6):603-617 [PubMed]
  • van Mello Norah M., Mol Femke, Ankum Willem M., Mol Ben Willem, van der Veen Fulco, Hajenius Petra J. Ectopic pregnancy: how the diagnostic and therapeutic management has changed Fertility and sterility 2012;98 (5):1066-1073 [PubMed]
  • van Mello Norah M., Zietse Carlijn S., Mol Femke, Zwart Joost J., van Roosmalen Jos, Bloemenkamp Kitty W., Ankum Willem M., van der Veen Fulco, Mol Ben Willem J., Hajenius Petra J. Severe maternal morbidity in ectopic pregnancy is not associated with maternal factors but may be associated with quality of care Fertility and sterility 2012;97 (3):623-629 [PubMed]
  • Smit Janine G., Kasius Jenneke C., Eijkemans Marinus J. C., Koks Carolien A. M., van Golde Ron, Oosterhuis Jurjen G. E., Nap Annemiek W., Scheffer Gabrielle J., Manger Petra A. P., Hoek Annemiek, Kaplan Mesrure, Schoot Dick B. C., van Heusden Arne M., Kuchenbecker Walter K. H., Perquin Denise A. M., Fleischer Kathrin, Kaaijk Eugenie M., Sluijmer Alexander, Friederich Jaap, Laven Joop S. E., van Hooff Marcel, Louwe Leonie A., Kwee Janet, Boomgaard Jantien J., de Koning Corry H., Janssen Ineke C. A. H., Mol Femke, Mol Ben W. J., Torrance Helen L., Broekmans Frank J. M. The inSIGHT study: costs and effects of routine hysteroscopy prior to a first IVF treatment cycle. A randomised controlled trial BMC Women's health 2012;12 (1):22 [PubMed]

2011

  • Mol F., van den Boogaard E., van Mello N. M., van der Veen F., Mol B. W., Ankum W. M., van Zonneveld P., Dijkman A. B., Verhoeve H. R., Mozes A., Goddijn M., Hajenius P. J. Guideline adherence in ectopic pregnancy management Human reproduction (Oxford, England) 2011;26 (2):307-315 [PubMed]
  • Ankum W. M., Mol F., Jamil A. Surgical management of tubal ectopic pregnancyin: Davor Jurkovic, Roy Farquharson, editors. Acute gynaecology and early pregnancy. Londen: RCOG Press; 2011. p. 145-151, ISBN 9781906985325

2010

  • Mol Femke, van Mello Norah M., Mol Ben W., van der Veen F., Ankum Willem M., Hajenius Petra J. Ectopic pregnancy and pelvic inflammatory disease: a renewed epidemic? European journal of obstetrics, gynecology, and reproductive biology 2010;151 (2):163-167 [PubMed]
  • van Mello N. M., Mol F., Opmeer B. C., de Bekker-Grob E. W., Essink-Bot M. L., Ankum W. M., Mol B. W., van der Veen F., Hajenius P. J. Salpingotomy or salpingectomy in tubal ectopic pregnancy: what do women prefer? Reproductive biomedicine online 2010;21 (5):687-693 [PubMed]

2009

  • van Mello N. M., Mol F., Mol B. W., Hajenius P. J. Conservative management of tubal ectopic pregnancy Best practice & research. Clinical obstetrics & gynaecology 2009;23 (4):509-518 [PubMed]

2008

  • Mol F., Mol B. W., Ankum W. M., van der Veen F., Hajenius P. J. Current evidence on surgery, systemic methotrexate and expectant management in the treatment of tubal ectopic pregnancy: a systematic review and meta-analysis Human reproduction update 2008;14 (4):309-319 [PubMed]
  • Mol Femke, Strandell Annika, Jurkovic Davor, Yalcinkaya Tamer, Verhoeve Harold R., Koks Carolien A. M., van der Linden Paul J. Q., Graziosi Giuseppe C. M., Thurkow Andreas L., Hoek Annemieke, Hogström Lars, Klinte Ingemar, Nilsson Kerstin, van Mello Norah M., Ankum Willem M., van der Veen Fulco, Mol Ben W. M., Hajenius Petra J., Hoek A., Willemsen W. N. P., Trimbos-Kemper G. C. M., van Zonneveld P., Bakkum E. A., Dijkman A. B., Thurkow A. L., van Dessel H. J. H. M., van der Linden P. J. Q., Kragt H., Graziosi C. G. M., Bouwmeester F. W., Oosterhuis G. J. E., Kleiverda G., Spaans W. A., Janssen C. A. H., van Beek J. J., Emanuel M. H., Visser H., Doornbos J. P. R., Pernet P. J. M., Friederich J., Otterlind L., Strandell A., Hogström L., Klinte I., Pettersson F., Sabetirad Z., Nilsson K., Franzén K., Tegerstedt G., Lindahl M. The ESEP study: salpingostomy versus salpingectomy for tubal ectopic pregnancy; the impact on future fertility: a randomised controlled trial BMC Women's health 2008;8 (1):11 [PubMed]
  • van Mello Norah M., Mol Femke, Adriaanse Albert H., Boss Erik A., Dijkman Antonius B., Doornbos Johannes P. R., Emanuel Mark Hans, Friederich Jaap, van der Leeuw-Harmsen Loes, Lips Jos P., van Santbrink Evert J. P., Verhoeve Harold R., Visser Harry, Ankum Willem M., van der Veen Fulco, Mol Ben W., Hajenius Petra J. The METEX study: methotrexate versus expectant management in women with ectopic pregnancy: a randomised controlled trial BMC Women's health 2008;8 (1):10 [PubMed]

2007

  • Hajenius P. J., Mol F., Mol B. W. J., Bossuyt P. M. M., Ankum W. M., van der Veen F. Interventions for tubal ectopic pregnancy Cochrane database of systematic reviews (Online) 2007;2007 (1):CD000324 [PubMed]

2004

  • Mol Femke, Strandell Annika, Mol Ben W. Improved fertility following conservative surgical treatment of ectopic pregnancy BJOG 2004;111 (6):635-636 [PubMed]