J. Hamann PhD publications

2021

• Hsiao Cheng-Chih, Fransen Nina L., van den Bosch Aletta M. R., Brandwijk Kim I. M., Huitinga Inge, Hamann J. rg, Smolders Joost White matter lesions in multiple sclerosis are enriched for CD20dim CD8+ tissue-resident memory T cells European journal of immunology 2021;51 (2):483-486 [PubMed]

2020

• de Groot Linsey E. S., van de Pol Marianne A., Fens Niki, Dierdorp Barbara S., Dekker Tamara, Kulik Wim, Majoor Christof J., Hamann J. rg, Sterk Peter J., Lutter René Corticosteroid Withdrawal-Induced Loss of Control in Mild to Moderate Asthma Is Independent of Classic Granulocyte Activation Chest 2020;157 (1):16-25 [PubMed]
• van der Poel Marlijn, Hoepel Willianne, Hamann J. rg, Huitinga Inge, Dunnen Jeroen den IgG Immune Complexes Break Immune Tolerance of Human Microglia Journal of immunology (Baltimore, Md. 2020;205 (9):2511-2518 [PubMed]
• Smolders Joost, Fransen Nina L., Hsiao Cheng-Chih, Hamann Jörg, Huitinga Inge Perivascular tissue resident memory T cells as therapeutic target in multiple sclerosis Expert review of neurotherapeutics 2020;20 (8):835-848 [PubMed]
• Fransen Nina L., Crusius Jakob B. A., Smolders Joost, Mizee Mark R., van Eden Corbert G., Luchetti Sabina, Remmerswaal Ester B. M., Hamann J. rg, Mason Matthew R. J., Huitinga Inge Post-mortem multiple sclerosis lesion pathology is influenced by single nucleotide polymorphisms Brain pathology (Zurich, Switzerland) 2020;30 (1):106-119 [PubMed]
• Böttcher Chotima, van der Poel Marlijn, Fernández-Zapata Camila, Schlickeiser Stephan, Leman Julia K. H., Hsiao Cheng-Chih, Mizee Mark R., Vincenten Maria C. J., Kunkel Desiree, Huitinga Inge, Hamann J. rg, Priller Josef Single-cell mass cytometry reveals complex myeloid cell composition in active lesions of progressive multiple sclerosis Acta neuropathologica communications 2020;8 (1):136 [PubMed]
• Fransen Nina L., Hsiao Cheng-Chih, van der Poel Marlijn, Engelenburg Hendrik J., Verdaasdonk Kim, Vincenten Maria C. J., Remmerswaal Ester B. M., Kuhlmann Tanja, Mason Matthew R. J., Hamann J. rg, Smolders Joost, Huitinga Inge Tissue-resident memory T cells invade the brain parenchyma in multiple sclerosis white matter lesions Brain 2020;143 (6):1714-1730 [PubMed]

2019

• Strainic Michael G., Liu Jinbo, An Fengqi, Bailey Erin, Esposito Andrew, Hamann J. rg, Heeger Peter S., Medof M. Edward CD55 Is Essential for CD103+ Dendritic Cell Tolerogenic Responses that Protect against Autoimmunity American journal of pathology 2019;189 (7):1386-1401 [PubMed]
• Martin Gaëlle H., Roy Nainita, Chakraborty Sohini, Desrichard Alexis, Chung Stephen S., Woolthuis Carolien M., Hu Wenhuo, Berezniuk Iryna, Garrett-Bakelman Francine E., Hamann J. rg, Devlin Sean M., Chan Timothy A., Park Christopher Y. CD97 is a critical regulator of acute myeloid leukemia stem cell function Journal of experimental medicine 2019;216 (10):2362-2377 [PubMed]
• de Groot Linsey E. S., Sabogal Piñeros Yanaika S., Bal Suzanne M., van de Pol Marianne A., Hamann Jörg, Sterk Peter J., Kulik Wim, Lutter René Do eosinophils contribute to oxidative stress in mild asthma? Clinical and experimental allergy 2019;49 (6):929-931 [PubMed]
• Hsiao Cheng-Chih, van der Poel Marlijn, van Ham Tjakko J., Hamann J. rg Macrophages Do Not Express the Phagocytic Receptor BAI1/ADGRB1 Frontiers in immunology 2019;10:962 [PubMed]
• de Groot Linsey E.S., van der Veen T. Anienke, Martinez Fernando O., Hamann Jörg, Lutter René, Melgert Barbro N. Oxidative stress and macrophages: Driving forces behind exacerbations of asthma and chronic obstructive pulmonary disease? American journal of physiology. Lung cellular and molecular physiology 2019;316 (2):L369-L384 [PubMed]
• van der Poel Marlijn, Ulas Thomas, Mizee Mark R, Hsiao Cheng-Chih, Miedema Suzanne S M, Adelia N. N., Schuurman Karianne G, Helder Boy, Tas Sander W, Schultze Joachim L, Hamann Jörg, Huitinga Inge Transcriptional profiling of human microglia reveals grey-white matter heterogeneity and multiple sclerosis-associated changes Nature communications 2019;10 (1):1139 [PubMed]
• Melief Jeroen, Orre Marie, Bossers Koen, van Eden Corbert G., Schuurman Karianne G., Mason Matthew R. J., Verhaagen Joost, Hamann J. rg, Huitinga Inge Transcriptome analysis of normal-appearing white matter reveals cortisol- and disease-associated gene expression profiles in multiple sclerosis Acta neuropathologica communications 2019;7 (1):60 [PubMed]

2018

• Hsiao Cheng-Chih, Chu Tai-Ying, Wu Chia-Jung, van den Biggelaar Maartje, Pabst Caroline, Hébert Josée, Kuijpers Taco W., Scicluna Brendon P., I Kuan-Yu, Chen Tse-Ching, Liebscher Ines, Hamann J. rg, Lin Hsi-Hsien The Adhesion G Protein-Coupled Receptor GPR97/ADGRG3 Is Expressed in Human Granulocytes and Triggers Antimicrobial Effector Functions Frontiers in immunology 2018;9:2830 [PubMed]
• Hilbig Doris, Dietrich Norman, Wandel Elke, Gonsior Susann, Sittig Doreen, Hamann J. rg, Aust Gabriela The interaction of CD97/ADGRE5 with β-catenin in adherens junctions is lost during colorectal carcinogenesis Frontiers in oncology 2018;8 (MAY) [PubMed]
• Smolders Joost, Heutinck Kirstin M., Fransen Nina L., Remmerswaal Ester B. M., Hombrink Pleun, ten Berge Ineke J. M., van Lier René A. W., Huitinga Inge, Hamann J. rg Tissue-resident memory T cells populate the human brain Nature communications 2018;9 (1) [PubMed]

2017

• Lin Hsi-Hsien, Hsiao Cheng-Chih, Pabst Caroline, Hébert Josée, Schöneberg Torsten, Hamann Jörg Adhesion GPCRs in Regulating Immune Responses and Inflammation Advances in immunology 2017;136:163-201 [PubMed]
• Hendrickx Debbie A. E., van Scheppingen Jackelien, van der Poel Marlijn, Bossers Koen, Schuurman Karianne G., van Eden Corbert G., Hol Elly M., Hamann Jörg, Huitinga Inge Gene Expression Profiling of Multiple Sclerosis Pathology Identifies Early Patterns of Demyelination Surrounding Chronic Active Lesions Frontiers in immunology 2017;8:1810 [PubMed]
• Mizee Mark R., Miedema Suzanne S. M., van der Poel Marlijn, Adelia N. N., Schuurman Karianne G., van Strien Miriam E., Melief Jeroen, Smolders Joost, Hendrickx Debbie A., Heutinck Kirstin M., Hamann Jorg, Huitinga Inge Isolation of primary microglia from the human post-mortem brain: effects of ante- and post-mortem variables Acta neuropathologica communications 2017;5 (1):16 [PubMed]
• de Kort Hanneke, Heutinck Kirstin M., Ruben Jurjen M., Ede V Silva Alessa, Wolthers Katja C., Hamann Jörg, ten Berge Ineke J. M. Primary Human Renal-Derived Tubular Epithelial Cells Fail to Recognize and Suppress BK Virus Infection Transplantation 2017;101 (8):1820-1829 [PubMed]
• Hendrickx Debbie A. E., van Eden Corbert G., Schuurman Karianne G., Hamann Jörg, Huitinga Inge Staining of HLA-DR, Iba1 and CD68 in human microglia reveals partially overlapping expression depending on cellular morphology and pathology Journal of neuroimmunology 2017;309:12-22 [PubMed]
• Choi Ivy Y., Karpus Olga N., Turner Jason D., Hardie Debbie, Marshall Jennifer L., de Hair Maria J. H., Maijer Karen I., Tak Paul P., Raza Karim, Hamann Jörg, Buckley Christopher D., Gerlag Danielle M., Filer Andrew Stromal cell markers are differentially expressed in the synovial tissue of patients with early arthritis PLoS ONE 2017;12 (8):e0182751 [PubMed]
• Alexander Stephen Ph, Kelly Eamonn, Marrion Neil V., Peters John A., Faccenda Elena, Harding Simon D., Pawson Adam J., Sharman Joanna L., Southan Christopher, Buneman O. Peter, Cidlowski John A., Christopoulos Arthur, Davenport Anthony P., Fabbro Doriano, Spedding Michael, Striessnig Jörg, Davies Jamie A., Abbracchio M.-P., Aldrich R., Al-Hosaini K., Arumugam T. V., Attali B., Bäck M., Barnes N. M., Bathgate R., Beart P. M., Becirovic E., Bettler B., Biel M., Birdsall N. J., Blaho V., Boison D., Bräuner-Osborne H., Bröer S., Bryant C., Burnstock G., Calo G., Catterall W. A., Ceruti S., Chan S. L., Chandy K. G., Chazot P., Chiang N., Chun J. J., Chung J.-J., Clapham D. E., Clapp L., Hamann Jörg, Kemp Stephan, Michel M. C. The concise guide to pharmacology 2017/18: Overview British journal of pharmacology 2017;174 (Suppl. 1):S1-S16 [PubMed]

2016

• Hamann Jörg, Hsiao Cheng-Chih, Lee Chang Sup, Ravichandran Kodi S., Lin Hsi-Hsien Adhesion GPCRs as Modulators of Immune Cell Function Handbook of experimental pharmacology 2016;234:329-350 [PubMed]
• Melief Jeroen, Koper Jan W., Endert Erik, Møller Holger J., Hamann Jörg, Uitdehaag Bernard M., Huitinga Inge Glucocorticoid receptor haplotypes conferring increased sensitivity (BclI and N363S) are associated with faster progression of multiple sclerosis Journal of neuroimmunology 2016;299:84-89 [PubMed]
• Karpus Olga N., Hsiao Cheng-Chih, de Kort Hanneke, Tak Paul P., Hamann Jörg Intracellular delivery of poly(I:C) induces apoptosis of fibroblast-like synoviocytes via an unknown dsRNA sensor Biochemical and biophysical research communications 2016;477 (3):343-349 [PubMed]
• Hamann Jörg, Petrenko Alexander G. Introduction: History of the Adhesion GPCR Field Handbook of experimental pharmacology 2016;234:1-11 [PubMed]
• Chang Gin-Wen, Hsiao Cheng-Chih, Peng Yen-Ming, Vieira Braga Felipe A., Kragten Natasja A. M., Remmerswaal Ester B. M., van de Garde Martijn D. B., Straussberg Rachel, König Gabriele M., Kostenis Evi, Knäuper Vera, Meyaard Linde, van Lier René A. W., van Gisbergen Klaas P. J. M., Lin Hsi-Hsien, Hamann Jörg The Adhesion G Protein-Coupled Receptor GPR56/ADGRG1 Is an Inhibitory Receptor on Human NK Cells Cell reports 2016;15 (8):1757-1770 [PubMed]

2015

• Hsiao Cheng-Chih Adhesion GPCRs CD97 and GPR56: From structural regulation to cellular function 2015. 179p. ISBN 9789461825742. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van Lier R. A. W.; Co-supervisors: Hamann Jörg, Lin H. H.)
• Monk Kelly R., Hamann Jörg, Langenhan Tobias, Nijmeijer Saskia, Schöneberg Torsten, Liebscher Ines Adhesion G Protein-Coupled Receptors: From In Vitro Pharmacology to In Vivo Mechanisms Molecular pharmacology 2015;88 (3):617-623 [PubMed]
• Vieira Braga Felipe A., Hertoghs Kirsten M. L., Kragten Natasja A. M., Doody Gina M., Barnes Nicholas A., Remmerswaal Ester B. M., Hsiao Cheng-Chih, Moerland Perry D., Wouters Diana, Derks Ingrid A. M., van Stijn Amber, Demkes Marc, Hamann Jörg, Eldering Eric, Nolte Martijn A., Tooze Reuben M., ten Berge Ineke J. M., van Gisbergen Klaas P. J. M., van Lier René A. W. Blimp-1 homolog Hobit identifies effector-type lymphocytes in humans European journal of immunology 2015;45 (10):2945-2958 [PubMed]
• Karpus Olga N., Kiener Hans P., Niederreiter Birgit, Yilmaz-Elis A. Seda, van der Kaa Jos, Ramaglia Valeria, Arens Ramon, Smolen Josef S., Botto Marina, Tak Paul P., Verbeek J. Sjef, Hamann Jörg CD55 deposited on synovial collagen fibers protects from immune complex-mediated arthritis Arthritis research & therapy 2015;17 (1):6 [PubMed]
• Hamann Jörg, Aust Gabriela, Araç Demet, Engel Felix B., Formstone Caroline, Fredriksson Robert, Hall Randy A., Harty Breanne L., Kirchhoff Christiane, Knapp Barbara, Krishnan Arunkumar, Liebscher Ines, Lin Hsi-Hsien, Martinelli David C., Monk Kelly R., Peeters Miriam C., Piao Xianhua, Prömel Simone, Schöneberg Torsten, Schwartz Thue W., Singer Kathleen, Stacey Martin, Ushkaryov Yuri A., Vallon Mario, Wolfrum Uwe, Wright Mathew W., Xu Lei, Langenhan Tobias, Schiöth Helgi B. International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors Pharmacological reviews 2015;67 (2):338-367 [PubMed]
• Hsiao Cheng-Chih, Keysselt Kerstin, Chen Hsin-Yi, Sittig Doreen, Hamann Jörg, Lin Hsi-Hsien, Aust Gabriela The Adhesion GPCR CD97/ADGRE5 inhibits apoptosis international journal of biochemistry & cell biology 2015;65:197-208 [PubMed]

2014

• Hsiao Cheng-Chih, Wang Wen-Chih, Kuo Wan-Lin, Chen Hsin-Yi, Chen Tse-Ching, Hamann Jörg, Lin Hsi-Hsien CD97 inhibits cell migration in human fibrosarcoma cells by modulating TIMP-2/MT1- MMP/MMP-2 activity--role of GPS autoproteolysis and functional cooperation between the N- and C-terminal fragments FEBS journal 2014;281 (21):4878-4891 [PubMed]
• van de Garde Martijn D. B., Martinez Fernando O., Melgert Barbro N., Hylkema Machteld N., Jonkers René E., Hamann Jörg Chronic exposure to glucocorticoids shapes gene expression and modulates innate and adaptive activation pathways in macrophages with distinct changes in leukocyte attraction Journal of immunology (Baltimore, Md. 2014;192 (3):1196-1208 [PubMed]
• Hendrickx Debbie A. E., Schuurman Karianne G., van Draanen Michael, Hamann Jörg, Huitinga Inge Enhanced uptake of multiple sclerosis-derived myelin by THP-1 macrophages and primary human microglia Journal of neuroinflammation 2014;11 (1):64 [PubMed]
• Liebscher Ines, Ackley Brian, Araç Demet, Ariestanti Donna M., Aust Gabriela, Bae Byoung-Il, Bista Bigyan R., Bridges James P., Duman Joseph G., Engel Felix B., Giera Stefanie, Goffinet André M., Hall Randy A., Hamann Jörg, Hartmann Nicole, Lin Hsi-Hsien, Liu Mingyao, Luo Rong, Mogha Amit, Monk Kelly R., Peeters Miriam C., Prömel Simone, Ressl Susanne, Schiöth Helgi B., Sigoillot Séverine M., Song Helen, Talbot William S., Tall Gregory G., White James P., Wolfrum Uwe, Xu Lei, Piao Xianhua New functions and signaling mechanisms for the class of adhesion G protein-coupled receptors Annals of the New York Academy of Sciences 2014;1333 (1):43-64 [PubMed]
• Zyryanova Tatiana, Schneider Rick, Adams Volker, Sittig Doreen, Kerner Christiane, Gebhardt Claudia, Ruffert Henrik, Glasmacher Stefan, Hepp Pierre, Punkt Karla, Neuhaus Jochen, Hamann Jörg, Aust Gabriela Skeletal muscle expression of the adhesion-GPCR CD97: CD97 deletion induces an abnormal structure of the sarcoplasmatic reticulum but does not impair skeletal muscle function PLoS ONE 2014;9 (6):e100513 [PubMed]
• Melief Jeroen The stress-axis in multiple sclerosis: Clinical, cellular and molecular aspects 2014. 208p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Swaab D. F.; Co-supervisors: Huitinga I., Hamann J. [=Jörg])
• Karpus Olga Nikolaevna The stromal component in rheumatoid arthritis: CD55 expression, cell death and beyond 2014. 143p. ISBN 9789461824912. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Tak P. P.; Co-supervisor: Hamann J. [=Jörg])
• García Samuel, Krausz Sarah, Ambarus Carmen A., Fernández Beatriz Malvar, Hartkamp Linda M., van Es Inge E., Hamann Jörg, Baeten Dominique L., Tak Paul P., Reedquist Kris A. Tie2 signaling cooperates with TNF to promote the pro-inflammatory activation of human macrophages independently of macrophage functional phenotype PLoS ONE 2014;9 (1):e82088 [PubMed]

2013

• Smolders Joost, Remmerswaal Ester B. M., Schuurman Karianne G., Melief Jeroen, van Eden Corbert G., van Lier René A. W., Huitinga Inge, Hamann Jörg Characteristics of differentiated CD8(+) and CD4 (+) T cells present in the human brain Acta neuropathologica 2013;126 (4):525-535 [PubMed]
• Martinez Fernando O., Helming Laura, Milde Ronny, Varin Audrey, Melgert Barbro N., Draijer Christina, Thomas Benjamin, Fabbri Marco, Crawshaw Anjali, Ho Ling Pei, ten Hacken Nick H., Cobos Jiménez Viviana, Kootstra Neeltje A., Hamann Jörg, Greaves David R., Locati Massimo, Mantovani Alberto, Gordon Siamon Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences Blood 2013;121 (9):E57-E69 [PubMed]
• Melief Jeroen, de Wit Stella J., van Eden Corbert G., Teunissen Charlotte, Hamann Jörg, Uitdehaag Bernard M., Swaab Dick, Huitinga Inge HPA axis activity in multiple sclerosis correlates with disease severity, lesion type and gene expression in normal-appearing white matter Acta neuropathologica 2013;126 (2):237-249 [PubMed]
• Aust Gabriela, Kerner Christiane, Gonsior Susann, Sittig Doreen, Schneider Hartmut, Buske Peter, Scholz Markus, Dietrich Norman, Oldenburg Sindy, Karpus Olga N., Galle Jörg, Amasheh Salah, Hamann Jörg Mice overexpressing CD97 in intestinal epithelial cells provide a unique model for mammalian postnatal intestinal cylindrical growth Molecular biology of the cell 2013;24 (14):2256-2268 [PubMed]
• Melief Jeroen, Schuurman Karianne G., van de Garde Martijn D. B., Smolders Joost, van Eijk Marco, Hamann Jörg, Huitinga Inge Microglia in normal appearing white matter of multiple sclerosis are alerted but immunosuppressed Glia 2013;61 (11):1848-1861 [PubMed]
• Hendrickx Debbie A. E., Koning Nathalie, Schuurman Karianne G., van Strien Miriam E., van Eden Corbert G., Hamann Jörg, Huitinga Inge Selective upregulation of scavenger receptors in and around demyelinating areas in multiple sclerosis Journal of neuropathology and experimental neurology 2013;72 (2):106-118 [PubMed]
• Karpus Olga N., Veninga Henrike, Hoek Robert M., Flierman Dennis, van Buul Jaap D., Vandenakker Corianne C., VanBavel Ed, Medof M. Edward, van Lier René A. W., Reedquist Kris A., Hamann Jörg Shear stress-dependent downregulation of the adhesion-G protein-coupled receptor CD97 on circulating leukocytes upon contact with its ligand CD55 Journal of immunology (Baltimore, Md. 2013;190 (7):3740-3748 [PubMed]
• Langenhan Tobias, Aust Gabriela, Hamann Jörg Sticky signaling--adhesion class G protein-coupled receptors take the stage Science signaling 2013;6 (276):re3 [PubMed]

2012

• Krausz Sarah, Garcia Samuel, Ambarus Carmen A., de Launay Daphne, Foster Martyn, Naiman Brian, Iverson William, Connor Jane R., Sleeman Matthew A., Coyle Anthony J., Hamann Jorg, Baeten Dominique, Tak Paul P., Reedquist Kris A. Angiopoietin-2 promotes inflammatory activation of human macrophages and is essential for murine experimental arthritis Annals of the rheumatic diseases 2012;71 (8):1402-1410 [PubMed]
• Cobos Jiménez Viviana, Booiman Thijs, de Taeye Steven W., van Dort Karel A., Rits Maarten A. N., Hamann Jörg, Kootstra Neeltje A. Differential expression of HIV-1 interfering factors in monocyte-derived macrophages stimulated with polarizing cytokines or interferons Scientific reports 2012;2:763 [PubMed]
• Araç Demet, Aust Gabriela, Calebiro Davide, Engel Felix B., Formstone Caroline, Goffinet André, Hamann Jörg, Kittel Robert J., Liebscher Ines, Lin Hsi-Hsien, Monk Kelly R., Petrenko Alexander, Piao Xianhua, Prömel Simone, Schiöth Helgi B., Schwartz Thue W., Stacey Martin, Ushkaryov Yuri A., Wobus Manja, Wolfrum Uwe, Xu Lei, Langenhan Tobias Dissecting signaling and functions of adhesion G protein-coupled receptors Annals of the New York Academy of Sciences 2012;1276 (1):1-25 [PubMed]
• van Gisbergen Klaas P. J. M., Kragten Natasja A. M., Hertoghs Kirsten M. L., Wensveen Felix M., Jonjic Stipan, Hamann Jörg, Nolte Martijn A., van Lier Rene A. W. Mouse Hobit is a homolog of the transcriptional repressor Blimp-1 that regulates NKT cell effector differentiation Nature immunology 2012;13 (9):864-871 [PubMed]
• Melief Jeroen, Koning Nathalie, Schuurman Karianne G., van de Garde Martijn D. B., Smolders Joost, Hoek Robert M., van Eijk Marco, Hamann Jörg, Huitinga Inge Phenotyping primary human microglia: Tight regulation of LPS responsiveness Glia 2012;60 (10):1506-1517 [PubMed]
• Heutinck Kirstin M., Kassies Jorien, Florquin Sandrine, ten Berge Ineke J. M., Hamann Jörg, Rowshani Ajda T. SerpinB9 expression in human renal tubular epithelial cells is induced by triggering of the viral dsRNA sensors TLR3, MDA5 and RIG-I Nephrology, dialysis, transplantation 2012;27 (7):2746-2754 [PubMed]
• Ambarus C. A., Krausz S., van Eijk M., Hamann J. [=Jörg], Radstake T. R. D. J., Reedquist K. A., Tak P. P., Baeten D. L. P. Systematic validation of specific phenotypic markers for in vitro polarized human macrophages Journal of immunological methods 2012;375 (1-2):196-206 [PubMed]
• Karpus Olga N., Heutinck Kirstin M., Wijnker Paul J. M., Tak Paul P., Hamann Jörg Triggering of the dsRNA Sensors TLR3, MDA5, and RIG-I Induces CD55 Expression in Synovial Fibroblasts PLoS ONE 2012;7 (5):e35606 [PubMed]
• Heutinck Kirstin M., Rowshani Ajda T., Kassies Jorien, Claessen Nike, van Donselaar-van der Pant Karlijn A. M. I., Bemelman Fréderike J., Eldering Eric, van Lier René A. W., Florquin Sandrine, ten Berge Ineke J. M., Hamann Jörg Viral double-stranded RNA sensors induce antiviral, pro-inflammatory, and pro-apoptotic responses in human renal tubular epithelial cells Kidney international 2012;82 (6):664-675 [PubMed]

2011

• Veninga Henrike, Hoek Robert M., de Vos Alex F., de Bruin Alex M., An Feng-Qi, van der Poll Tom, van Lier René A. W., Medof M. Edward, Hamann Jörg A novel role for CD55 in granulocyte homeostasis and anti-bacterial host defense PLoS ONE 2011;6 (10):e24431 [PubMed]
• Veninga Henrike, de Groot Dorien M., McCloskey Natalie, Owens Bronwyn M., Dessing Mark C., Verbeek J. Sjef, Nourshargh Sussan, van Eenennaam Hans, Boots Annemieke M., Hamann Jörg CD97 antibody depletes granulocytes in mice under conditions of acute inflammation via a Fc receptor-dependent mechanism Journal of leukocyte biology 2011;89 (3):413-421 [PubMed]
• Hamann Jörg, Veninga Henrike, de Groot Dorien M., Visser Lizette, Hofstra Claudia L., Tak Paul P., Laman Jon D., Boots Annemieke M., van Eenennaam Hans CD97 in Leukocyte Trafficking Advances in experimental medicine and biology 2011;706:128-137 [PubMed]
• Gordon Siamon, Hamann Jörg, Lin Hsi-Hsien, Stacey Martin Cover picture: eur. J. Immunol. 9/11 European journal of immunology 2011;41 (9):n/a
• Kop Else N. EGF-TM7 receptors in rheumatoid arthritis 2011. 180p. ISBN 9789090262017. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Tak P. P.; Co-supervisor: Hamann Jörg)
• Gordon Siamon, Hamann Jörg, Lin Hsi-Hsien, Stacey Martin F4/80 and the related adhesion-GPCRs European journal of immunology 2011;41 (9):2472-2476 [PubMed]
• Davies John Q., Lin Hsi-Hsien, Stacey Martin, Yona Simon, Chang Gin-Wen, Gordon Siamon, Hamann Jörg, Campo Leticia, Han Cheng, Chan Peter, Fox Stephen B. Leukocyte adhesion-GPCR EMR2 is aberrantly expressed in human breast carcinomas and is associated with patient survival Oncology reports 2011;25 (3):619-627 [PubMed]
• Cobos-Jiménez Viviana, Booiman Thijs, Hamann Jörg, Kootstra Neeltje A. Macrophages and HIV-1 Current opinion in HIV and AIDS 2011;6 (5):385-390 [PubMed]
• Heutinck Kirstin M. Recognition of infection and inflammation in the kidney 2011. 208p. ISBN 9789490371722. [UvA Dissertations Online] University of Amsterdam. (Supervisors: ten Berge R. J. M., van Lier R. A. W.; Co-supervisor: Hamann Jörg)
• Peng Yen-Ming, van de Garde Martijn D. B., Cheng Kai-Fong, Baars Paul A., Remmerswaal Ester B. M., van Lier René A. W., Mackay Charles R., Lin Hsi-Hsien, Hamann Jörg Specific expression of GPR56 by human cytotoxic lymphocytes Journal of leukocyte biology 2011;90 (4):735-740 [PubMed]
• Reuwer Anne, van Eijk Marco, Houttuijn-Bloemendaal Felicia, van der Loos Chris, Claessen Nike, Teeling Peter, Kastelein J. J., Hamann Jörg, Goffin Vincent, von der Thüsen Jan, Twickler Marcel, Aten Jan The prolactin receptor is expressed in macrophages within human carotid atherosclerotic plaques: a role for prolactin in atherogenesis? Journal of endocrinology 2011;208 (2):107-117 [PubMed]

2010

• van Olffen Ronald W., de Bruin Alex M., Vos Mariska, Staniszewska Anna D., Hamann Jörg, van Lier René A. W., de Vries Carlie J. M., Nolte Martijn A. CD70-Driven Chronic Immune Activation Is Protective against Atherosclerosis Journal of innate immunity 2010;2 (4):344-352 [PubMed]
• de Colvenaer Veerle, Taveirne Sylvie, Hamann Jörg, de Bruin Alex M., de Smedt Magda, Taghon Tom, Vandekerckhove Bart, Plum Jean, van Lier René, Leclercq Georges Continuous CD27 triggering in vivo strongly reduces NK cell numbers European journal of immunology 2010;40 (4):1107-1117 [PubMed]
• Hoek Robert M., de Launay Daphne, Kop Else N., Yilmaz-Elis A. Seda, Lin Feng, Reedquist Kris A., Verbeek J. Sjef, Medof M. Edward, Tak Paul P., Hamann Jörg Deletion of either CD55 or CD97 ameliorates arthritis in mouse models Arthritis and rheumatism 2010;62 (4):1036-1042 [PubMed]
• van Eijk Marco, Aust Gabriela, Brouwer Michael S. M., van Meurs Marjan, Voerman Jane S. A., Dijke I. Esmé, Pouwels Walter, Sändig Irene, Wandel Elke, Aerts Johannes M. F. G., Boot Rolf G., Laman Jon D., Hamann Jörg Differential expression of the EGF-TM7 family members CD97 and EMR2 in lipid-laden macrophages in atherosclerosis, multiple sclerosis and Gaucher disease Immunology letters 2010;129 (2):64-71 [PubMed]
• Koning Nathalie, van Eijk Marco, Pouwels Walter, Brouwer Michael S. M., Voehringer David, Huitinga Inge, Hoek Robert M., Raes Geert, Hamann Jörg Expression of the Inhibitory CD200 Receptor Is Associated with Alternative Macrophage Activation Journal of innate immunity 2010;2 (2):195-200 [PubMed]
• Veninga Henrike In vivo studies on the role of adhesion-GPCR CD97 in immunity 2010. 140p. ISBN 9789085706052. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van Lier R. A. W.; Co-supervisor: Hamann Jörg)
• Becker Susann, Wandel Elke, Wobus Manja, Schneider Rick, Amasheh Salah, Sittig Doreen, Kerner Christiane, Naumann Ronald, Hamann Joerg, Aust Gabriela Overexpression of CD97 in Intestinal Epithelial Cells of Transgenic Mice Attenuates Colitis by Strengthening Adherens Junctions PLoS ONE 2010;5 (1):e8507 [PubMed]
• Heutinck Kirstin M., ten Berge Ineke J. M., Hack C. Erik, Hamann Jörg, Rowshani Ajda T. Serine proteases of the human immune system in health and disease Molecular immunology 2010;47 (11-12):1943-1955 [PubMed]
• de Launay Daphne, Vreijling Jeroen, Hartkamp Linda M., Karpus Olga N., Abreu Joana R. F., van Maanen Marjolein A., Sanders Marjolein E., Grabiec Aleksander M., Hamann Jörg, Orum Henrik, Vervoordeldonk Margriet J., Fluiter Kees, Tak Paul P., Reedquist Kris A. Silencing the Expression of Ras Family GTPase Homologues Decreases Inflammation and Joint Destruction in Experimental Arthritis American journal of pathology 2010;177 (6):3010-3024 [PubMed]

2009

• Kop Else N., Matmati Mourad, Pouwels Walter, Leclercq Georges, Tak Paul P., Hamann Jörg Differential expression of CD97 on human lymphocyte subsets and limited effect of CD97 antibodies on allogeneic T-cell stimulation Immunology letters 2009;123 (2):160-168 [PubMed]
• van Olffen Ronald W., Koning Nathalie, van Gisbergen Klaas P. J. M., Wensveen Felix M., Hoek Robert M., Boon Louis, Hamann Jörg, van Lier Rene A. W., Nolte Martijn A. GITR triggering induces expansion of both effector and regulatory CD4+ T cells in vivo Journal of immunology (Baltimore, Md. 2009;182 (12):7490-7500 [PubMed]
• de Groot Dorien M., Vogel Gerard, Dulos John, Teeuwen Leonie, Stebbins Karin, Hamann Jörg, Owens Bronwyn M., van Eenennaam Hans, Bos Ebo, Boots Annemieke M. Therapeutic Antibody Targeting of CD97 in Experimental Arthritis: the Role of Antigen Expression, Shedding, and Internalization on the Pharmacokinetics of Anti-CD97 Monoclonal Antibody 1B2 Journal of immunology (Baltimore, Md. 2009;183 (6):4127-4134 [PubMed]

2008

• Matmati Mourad A diverse and still evolving family of receptors on the leukocyte surface 2008. 134p. [UvA Dissertations Online] University of Amsterdam. (Supervisors: van Lier R. A. W., Leclerq G.; Co-supervisor: Hamann Jörg)
• Veninga Henrike, Becker Susann, Hoek Robert M., Wobus Manja, Wandel Elke, van der Kaa Jos, van der Valk Martin, de Vos Alex F., Haase Hannelore, Owens Bronwyn, van der Poll Tom, van Lier René A. W., Verbeek J. Sjef, Aust Gabriela, Hamann Jörg Analysis of CD97 expression and manipulation: antibody treatment but not gene targeting curtails granulocyte migration Journal of immunology (Baltimore, Md. 2008;181 (9):6574-6583 [PubMed]
• Vossen Mireille T. M., Matmati Mourad, Hertoghs Kirsten M. L., Baars Paul A., Gent Mi-Ran, Leclercq Georges, Hamann Jörg, Kuijpers Taco W., van Lier René A. W. CD27 defines phenotypically and functionally different human NK cell subsets Journal of immunology (Baltimore, Md. 2008;180 (6):3739-3745 [PubMed]
• van Pel Melissa, Hagoort Henny, Hamann Jörg, Fibbe Willem E. CD97 is differentially expressed on murine hematopoietic stem-and progenitor-cells Haematologica 2008;93 (8):1137-1144 [PubMed]
• van Pel Melissa, Hagoort Henny, Kwakkenbos Mark J., Hamann Jörg, Fibbe Willem E. Differential role of CD97 in interleukin-8-induced and granulocyte-colony stimulating factor-induced hematopoietic stem and progenitor cell mobilization Haematologica 2008;93 (4):601-604 [PubMed]
• Yona Simon, Lin Hsi-Hsien, Dri Pietro, Davies John Q., Hayhoe Richard P. G., Lewis Sion M., Heinsbroek Sigrid E. M., Brown K. Alun, Perretti Mauro, Hamann Jörg, Treacher David F., Gordon Siamon, Stacey Martin Ligation of the adhesion-GPCR EMR2 regulates human neutrophil function FASEB journal 2008;22 (3):741-751 [PubMed]

2007

• Chang Gin-Wen, Davies John Q., Stacey Martin, Yona Simon, Bowdish Dawn M. E., Hamann Jörg, Chen Tse-Ching, Lin Chun-Yen, Gordon Siamon, Lin Hsi-Hsien CD312, the human adhesion-GPCR EMR2, is differentially expressed during differentiation, maturation, and activation of myeloid cells Biochemical and biophysical research communications 2007;353 (1):133-138 [PubMed]
• Hamann Jorg, Koning Nathalie, Pouwels Walter, Ulfman Laurien H., van Eijk Marco, Stacey Martin, Lin Hsi-Hsien, Gordon Siamon, Kwakkenbos Mark J. EMR1, the human homolog of F4/80, is an eosinophil-specific receptor European journal of immunology 2007;37 (10):2797-2802 [PubMed]
• Matmati Mourad, Pouwels Walter, van Bruggen Robin, Jansen Machiel, Hoek Robert M., Verhoeven Arthur J., Hamann Jörg The human EGF-TM7 receptor EMR3 is a marker for mature granulocytes Journal of leukocyte biology 2007;81 (2):440-448 [PubMed]

2006

• Boon Elles M. J., Pouwels Walter, Redeker Sandra, Joosten Sander P. J., Hamann Jörg, van der Neut Ronald, Pals Steven T. Activation of Wnt signaling in the intestinal mucosa of Apc +/min mice does not cause overexpression of the receptor tyrosine kinase Met Cancer science 2006;97 (8):710-715 [PubMed]
• Kwakkenbos Mark J., Matmati Mourad, Madsen Ole, Pouwels Walter, Wang YongYi, Bontrop Ronald E., Heidt Peter J., Hoek Robert M., Hamann Jörg An unusual mode of concerted evolution of the EGF-TM7 receptor chimera EMR2 FASEB journal 2006;20 (14):2582-2584 [PubMed]
• Kop Else N., Adriaansen Janik, Smeets Tom J. M., Vervoordeldonk Margriet J., van Lier René A. W., Hamann Jörg, Tak Paul P. CD97 neutralisation increases resistance to collagen-induced arthritis in mice Arthritis research & therapy 2006;8 (5):R155 [PubMed]
• Wobus Manja, Huber Otmar, Hamann Jörg, Aust Gabriela CD97 overexpression in tumor cells at the invasion front in colorectal cancer (CC) is independently regulated of the canonical Wnt pathway Molecular carcinogenesis 2006;45 (11):881-886 [PubMed]

2005

• Bennink Roelof J., Hamann Jörg, de Bruin Kora, ten Kate Fiebo J. W., van Deventer Sander J. H., te Velde Anje A. Dedicated pinhole SPECT of intestinal neutrophil recruitment in a mouse model of dextran sulfate sodium-induced colitis Journal of nuclear medicine 2005;46 (3):526-531 [PubMed]
• Kwakkenbos Mark J., Pouwels Walter, Matmati Mourad, Stacey Martin, Lin Hsi-Hsien, Gordon Siamon, van Lier René A. W., Hamann Jörg Expression of the largest CD97 and EMR2 isoforms on leukocytes facilitates a specific interaction with chondroitin sulfate on B cells Journal of leukocyte biology 2005;77 (1):112-119 [PubMed]
• Kop Else N., Kwakkenbos Mark J., Teske Gwendoline J. D., Kraan Maarten C., Smeets Tom J., Stacey Martin, Lin Hsi-Hsien, Tak Paul P., Hamann Jörg Identification of the epidermal growth factor-TM7 receptor EMR2 and its ligand dermatan sulfate in rheumatoid synovial tissue Arthritis and rheumatism 2005;52 (2):442-450 [PubMed]

2004

• Kwakkenbos M. J. CD97 and EMR2: receptors on the move 2004. 136p. ISBN 9789090182292. [UvA Dissertations Online] University of Amsterdam. (Supervisor: van Lier R. A. W.; Co-supervisor: Hamann Jörg)
• Wobus Manja, Vogel Björn, Schmücking Eike, Hamann Jörg, Aust Gabriela N-glycosylation of CD97 within the EGF domains is crucial for epitope accessibility in normal and malignant cells as well as CD55 ligand binding International journal of cancer. Journal international du cancer 2004;112 (5):815-822 [PubMed]
• Kwakkenbos Mark J., Kop Else N., Stacey Martin, Matmati Mourad, Gordon Siamon, Lin Hsi-Hsien, Hamann Jörg The EGF-TM7 family: a postgenomic view Immunogenetics 2004;55 (10):655-666 [PubMed]
• Hamann Jörg The EGF-TM7 family of the rat Immunogenetics 2004;56 (9):679-681 [PubMed]
• Leemans Jaklien C., te Velde Anje A., Florquin Sandrine, Bennink Roelof J., de Bruin Kora, van Lier René A. W., van der Poll Tom, Hamann Jörg The epidermal growth factor-seven transmembrane (EGF-TM7) receptor CD97 is required for neutrophil migration and host defense Journal of immunology (Baltimore, Md. 2004;172 (2):1125-1131 [PubMed]

2003

• Aust Gabriela, Hamann Jörg, Schilling Nicole, Wobus Manja Detection of alternatively spliced EMR2 mRNAs in colorectal tumor cell lines but rare expression of the molecule in colorectal adenocarcinomas Virchows Archiv 2003;443 (1):32-37 [PubMed]
• Hamann Jörg, Kwakkenbos Mark J., de Jong Esther C., Heus Henk, Olsen Anne S., van Lier René A. W. Inactivation of the EGF-TM7 receptor EMR4 after the Pan-Homo divergence European journal of immunology 2003;33 (5):1365-1371 [PubMed]
• Chang Gin-Wen, Stacey Martin, Kwakkenbos Mark J., Hamann Jörg, Gordon Siamon, Lin Hsi-Hsien Proteolytic cleavage of the EMR2 receptor requires both the extracellular stalk and the GPS motif FEBS letters 2003;547 (1-3):145-150 [PubMed]
• Stacey Martin, Chang Gin-Wen, Davies John Q., Kwakkenbos Mark J., Sanderson Ralph D., Hamann Jörg, Gordon Siamon, Lin Hsi-Hsien The epidermal growth factor-like domains of the human EMR2 receptor mediate cell attachment through chondroitin sulfate glycosaminoglycans Blood 2003;102 (8):2916-2924 [PubMed]

2002

• Aust Gabriela, Steinert Matthias, Schütz Alexander, Boltze Carsten, Wahlbuhl Mandy, Hamann Jörg, Wobus Manja CD97, but not its closely related EGF-TM7 family member EMR2, is expressed on gastric, pancreatic, and esophageal carcinomas American journal of clinical pathology 2002;118 (5):699-707 [PubMed]
• Boulday Gwénola, Hamann Jörg, Soulillou Jean-Paul, Charreau Béatrice CD97-decay-accelerating factor interaction is not involved in leukocyte adhesion to endothelial cells Transplantation 2002;73 (3):429-436 [PubMed]
• Steinert Matthias, Wobus Manja, Boltze Carsten, Schütz Alexander, Wahlbuhl Mandy, Hamann Jörg, Aust Gabriela Expression and regulation of CD97 in colorectal carcinoma cell lines and tumor tissues American journal of pathology 2002;161 (5):1657-1667 [PubMed]
• Visser Lizette, de Vos Alex F., Hamann Jörg, Melief Marie-José, van Meurs Marjan, van Lier René A. W., Laman Jon D., Hintzen Rogier Q. Expression of the EGF-TM7 receptor CD97 and its ligand CD55 (DAF) in multiple sclerosis Journal of neuroimmunology 2002;132 (1-2):156-163 [PubMed]
• Kwakkenbos Mark J., Chang Gin-Wen, Lin Hsi-Hsien, Pouwels Walter, de Jong Esther C., van Lier René A. W., Gordon Siamon, Hamann Jörg The human EGF-TM7 family member EMR2 is a heterodimeric receptor expressed on myeloid cells Journal of leukocyte biology 2002;71 (5):854-862 [PubMed]

2001

• Jaspars L. H., Vos W., Aust G., van Lier R. A., Hamann J. [=Jörg] Tissue distribution of the human CD97 EGF-TM7 receptor Tissue antigens 2001;57 (4):325-331 [PubMed]

2000

• Lin H. H., Stacey M., Hamann J. [=Jörg], Gordon S., McKnight A. J. Human EMR2, a novel EGF-TM7 molecule on chromosome 19p13.1, is closely related to CD97 Genomics 2000;67 (2):188-200 [PubMed]
• Hamann J. [=Jörg], van Zeventer C., Bijl A., Molenaar C., Tesselaar K., van Lier R. A. Molecular cloning and characterization of mouse CD97 International immunology 2000;12 (4):439-448 [PubMed]

1999

• Hamann J. [=Jörg], Wishaupt J. O., van Lier R. A., Smeets T. J., Breedveld F. C., Tak P. P. Expression of the activation antigen CD97 and its ligand CD55 in rheumatoid synovial tissue Arthritis and rheumatism 1999;42 (4):650-658 [PubMed]
• Carver E. A., Hamann J. [=Jörg], Olsen A. S., Stubbs L. Physical mapping of EMR1 and CD97 in human Chromosome 19 and assignment of Cd97 to mouse Chromosome 8 suggest an ancient genomic duplication Mammalian genome 1999;10 (10):1039-1040 [PubMed]

1998

• Hamann J. [=Jörg], Stortelers C., Kiss-Toth E., Vogel B., Eichler W., van Lier R. A. Characterization of the CD55 (DAF)-binding site on the seven-span transmembrane receptor CD97 European journal of immunology 1998;28 (5):1701-1707 [PubMed]

1997

• Hamann J. [=Jörg], Montgomery K. T., Lau S., Kucherlapati R., van Lier R. A. AICL: a new activation-induced antigen encoded by the human NK gene complex Immunogenetics 1997;45 (5):295-300 [PubMed]
• Eichler W., Hamann J. [=Jörg], Aust G. Expression characteristics of the human CD97 antigen Tissue antigens 1997;50 (5):429-438 [PubMed]

1996

• van Lier R. A., Eichler W., Hamann J. [=Jörg] Sevenspan transmembrane molecules: novel receptors involved in leukocyte adhesion Immunology letters 1996;54 (2-3):185-187 [PubMed]
• Hamann J. [=Jörg], Hartmann E., van Lier R. A. Structure of the human CD97 gene: exon shuffling has generated a new type of seven-span transmembrane molecule related to the secretin receptor superfamily Genomics 1996;32 (1):144-147 [PubMed]
• Hamann J. [=Jörg], Vogel B., van Schijndel G. M., van Lier R. A. The seven-span transmembrane receptor CD97 has a cellular ligand (CD55, DAF) Journal of experimental medicine 1996;184 (3):1185-1189 [PubMed]

1995

• Bezouska K., Nepovím A., Horváth O., Pospísil M., Hamann J. [=Jörg], Feizi T. CD 69 antigen of human lymphocytes is a calcium-dependent carbohydrate-binding protein Biochemical and biophysical research communications 1995;208 (1):68-74 [PubMed]
• Hamann J. [=Jörg], Eichler W., Hamann D., Kerstens H. M., Poddighe P. J., Hoovers J. M., Hartmann E., Strauss M., van Lier R. A. Expression cloning and chromosomal mapping of the leukocyte activation antigen CD97, a new seven-span transmembrane molecule of the secretion receptor superfamily with an unusual extracellular domain Journal of immunology (Baltimore, Md. 1995;155 (4):1942-1950 [PubMed]

1994

• Santis A. G., López-Cabrera M., Hamann J. [=Jörg], Strauss M., Sánchez-Madrid F. Structure of the gene coding for the human early lymphocyte activation antigen CD69: a C-type lectin receptor evolutionarily related with the gene families of natural killer cell-specific receptors European journal of immunology 1994;24 (7):1692-1697 [PubMed]

1993

• Hamann J. [=Jörg], Fiebig H., Strauss M. Expression cloning of the early activation antigen CD69, a type II integral membrane protein with a C-type lectin domain Journal of immunology (Baltimore, Md. 1993;150 (11):4920-4927 [PubMed]
• Schnittger S., Hamann J. [=Jörg], Dannenberg C., Fiebig H., Strauss M., Fonatsch C. Regional sublocalization of the human CD69 gene to chromosome bands 12p12.3-p13.2, the predicted region of the human natural killer cell gene complex European journal of immunology 1993;23 (10):2711-2713 [PubMed]