N.A. Kootstra PhD publications

2020

• Larsen Mads Delbo, de Graaf Erik L, Sonneveld Myrthe E, Plomp H Rosina, Nouta Jan, Hoepel Willianne, Chen Hung-Jen, Linty Federica, Visser Remco, Brinkhaus Maximilian, Šuštić Tonći, de Taeye Steven W, Bentlage Arthur E H, Toivonen Suvi, Koeleman Carolien A M, Sainio Susanna, Kootstra Neeltje A, Brouwer Philip J M, Geyer Chiara Elisabeth, Derksen Ninotska I L, Wolbink Gertjan, de Winther Menno, Sanders Rogier W, van Gils Marit J, de Bruin Sanne, Vlaar Alexander P J, Rispens Theo, den Dunnen Jeroen, Zaaijer Hans L, Wuhrer Manfred, Ellen van der Schoot C, Vidarsson Gestur Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity Science 2020 [PubMed]
• Darcis Gilles, Kootstra Neeltje A., Hooibrink Berend, van Montfort Thijs, Maurer Irma, Groen Kevin, Jurriaans Suzanne, Bakker Margreet, van Lint Carine, Berkhout Ben, Pasternak Alexander O. CD32+CD4+ T Cells Are Highly Enriched for HIV DNA and Can Support Transcriptional Latency Cell reports 2020;30 (7):2284-2296.e3 [PubMed]
• Merat Sabrina J., Bru Camille, van de Berg Dorien, Molenkamp Richard, Tarr Alexander W., Koekkoek Sylvie, Kootstra Neeltje A., Prins Maria, Ball Jonathan K., Bakker Arjen Q., de Jong Menno D., Spits Hergen, Beaumont Tim, Schinkel Janke Erratum to: ‘Cross-genotype AR3-specific neutralizing antibodies confer long-term protection in injecting drug users after HCV clearance’ (J Hepatol 2019; 71(1): 14-24) (Journal of Hepatology (2019) 71(1) (14–24), (S016882781930128X), (10.1016/j.jhep.2019.02.013)) Journal of hepatology 2020;73 (4):999-1000 [PubMed]
• Kruize Zita, Maurer Irma, Boeser-Nunnink Brigitte D. M., Booiman Thijs, Kootstra Neeltje A. Genetic variations in the host dependency factors ALCAM and TPST2 impact HIV-1 disease progression AIDS (London, England) 2020;34 (9):1303-1312 [PubMed]
• Hoornenborg Elske, Coyer Liza, Boyd Anders, Achterbergh Roel Christiaan Alfons, Schim van der Loeff Maarten Franciscus, Bruisten Sylvia, de Vries Henry John Christiaan, Koopsen Jelle, van de Laar Thijs J. W., Prins Maria, van Bergen J. E. A. M., de Bree G. J., Brokx P., Deug F., Heidenrijk M., Prins M., Reiss P., van der Valk M., Davidovich U., Geerlings S. E., Hoornenborg E., Oomen A., Sighem A. van, Zuilhof W., Bruinderink M. L. Groot, Achterbergh R. C. A., van Agtmael M., Ananworanich J., van de Beek D., van den Berk G. E. L., Bezemer D., van Bijnen A., Dijkstra M., Geijtenbeek T. B. H., Godfried M. H., Goorhuis A., Hankins C. A., Hogewoning A., Hovius J. W., Kootstra N. A., Lauw F., van der Meer J. T., Mulder B. J., Nellen F. J., van der Poll T., van Rooijen M. S., Sonder G. J., de Vries H. J., Wiersinga W. J., Wit F. W. High incidence of HCV in HIV-negative men who have sex with men using pre-exposure prophylaxis Journal of hepatology 2020;72 (5):855-864 [PubMed]
• Vujkovic-Cvijin I., Sortino O., Verheij E., Sklar J., Wit F. W., Kootstra N. A., Sellers B., Brenchley J. M., Ananworanich J., Loeff M. Schim van der, Belkaid Y., Reiss P., Sereti I. HIV-associated gut dysbiosis is independent of sexual practice and correlates with noncommunicable diseases Nature communications 2020;11 (1) [PubMed]
• Verboeket Sebastiaan O, Wit Ferdinand W, Verheij Eveline, van Zoest Rosan A, Kootstra Neeltje A, van der Valk Marc, Prins Jan M, Schim van der Loeff Maarten F, Reiss Peter HIV-negative Men Who Have Sex with Men have higher CD8+ T-cell Counts and Lower CD4+/CD8+ T-cell Ratios compared to HIV-negative Heterosexual Men Journal of infectious diseases 2020 [PubMed]
• Kruize Zita, Maurer Irma, van Dort Karel A., van den Elshout Mark A. M., Hoornenborg Elske, Booiman Thijs, Prins Maria, Kootstra Neeltje A. Human immunodeficiency virus-negative men who have sex with men have an altered T-Cell phenotype and bioenergy metabolism Open forum infectious diseases 2020;7 (8) [PubMed]
• Connell Bridgette J., Hermans Lucas E., Wensing Annemarie M. J., Schellens Ingrid, Schipper Pauline J., van Ham Petra M., de Jong Dorien T. C. M., Otto Sigrid, Mathe Tholakele, Moraba Robert, Borghans José A. M., Papathanasopoulos Maria A., Kruize Zita, Venter Francois W. D., Kootstra Neeltje A., Tempelman Hugo, Tesselaar Kiki, Nijhuis Monique Immune activation correlates with and predicts CXCR4 co-receptor tropism switch in HIV-1 infection Scientific reports 2020;10 (1) [PubMed]
• Stunnenberg Melissa, van Pul Lisa, Sprokholt Joris K., van Dort Karel A., Gringhuis Sonja I., Geijtenbeek Teunis B. H., Kootstra Neeltje A. MAVS genetic variation is associated with decreased HIV-1 replication in vitro and reduced cd4+ t cell infection in HIV-1-infected individuals Viruses 2020;12 (7) [PubMed]
• de Francesco Davide, Sabin Caroline A., Reiss Peter, Kootstra Neeltje A. Monocyte and T Cell Immune Phenotypic Profiles Associated With Age Advancement Differ Between People With HIV, Lifestyle-Comparable Controls and Blood Donors Frontiers in immunology 2020;11 [PubMed]
• Kroeze Stefanie, Rossouw Theresa M, Steel Helen C, Wit Ferdinand W, Kityo Cissy M, Siwale Margaret, Akanmu Sulaimon, Mandaliya Kishor, De Jager Marleen, Ondoa Pascale, Reiss Peter, De Wit Tobias F Rinke, Kootstra Neeltje A, Hamers Raph L Plasma inflammatory biomarkers predict CD4+ T-cell recovery and viral rebound in HIV-1 infected Africans on suppressive antiretroviral therapy Journal of infectious diseases 2020 [PubMed]
• Brouwer Philip J.M., Caniels Tom G., van der Straten Karlijn, Snitselaar Jonne L., Aldon Yoann, Bangaru Sandhya, Torres Jonathan L., Okba Nisreen M.A., Claireaux Mathieu, Kerster Gius, Bentlage Arthur E.H., van Haaren Marlies M., Guerra Denise, Burger Judith A., Schermer Edith E., Verheul Kirsten D., van der Velde Niels, van der Kooi Alex, van Schooten Jelle, van Breemen Mariëlle J., Bijl Tom P.L., Sliepen Kwinten, Aartse Aafke, Derking Ronald, Bontjer Ilja, Kootstra Neeltje A., Joost Wiersinga W., Vidarsson Gestur, Haagmans Bart L., Ward Andrew B., de Bree Godelieve J., Sanders Rogier W., van Gils Marit J. Potent neutralizing antibodies from COVID-19 patients define multiple targets of vulnerability Science 2020;369 (6504):643-650 [PubMed]
• van Bilsen Ward P H, Zimmermann Hanne M L, Boyd Anders, Coyer Liza, van der Hoek Lia, Kootstra Neeltje A, Hoornenborg Elske, Prins Maria, Schim van der Loeff Maarten F, Davidovich Udi, Matser Amy Sexual behavior and its determinants during COVID-19 restrictions among men who have sex with men in Amsterdam JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES 2020 [PubMed]
• Engel Tanja, Raffenberg Marieke, Schoepf Isabella C, Kootstra Neeltje A, Reiss Peter, Thorball Christian W, Hasse Barbara, Hirzel Cédric, Wissel Kerstin, Roth Jan A, Bernasconi Enos, Darling Katharine E A, Calmy Alexandra, Fellay Jacques, Kouyos Roger D, Günthard Huldrych F, Ledergerber Bruno, Tarr Philip E Telomere Length, Traditional Risk Factors, HIV-related Factors and Coronary Artery Disease Events in Swiss Persons Living with HIV Clinical infectious diseases 2020 [PubMed]

2019

• Merat Sabrina J., Bru Camille, van de Berg Dorien, Molenkamp Richard, Tarr Alexander W., Koekkoek Sylvie, Kootstra Neeltje A., Prins Maria, Ball Jonathan K., Bakker Arjen Q., de Jong Menno D., Spits Hergen, Beaumont Tim, Schinkel Janke Cross-genotype AR3-specific neutralizing antibodies confer long-term protection in injecting drug users after HCV clearance Journal of hepatology 2019;71 (1):14-24 [PubMed]
• de Francesco Davide, Wit Ferdinand W., Bürkle Alexander, Oehlke Sebastian, Kootstra Neeltje A., Winston Alan, Franceschi Claudio, Garagnani Paolo, Pirazzini Chiara, Libert Claude, Grune Tilman, Weber Daniela, Jansen Eugène H. J. M., Sabin Caroline A., Reiss Peter, Geurtsen Gerrit Do people living with HIV experience greater age advancement than their HIV-negative counterparts? AIDS (London, England) 2019;33 (2):259-268 [PubMed]
• van den Hof Malon, Haneveld Mirthe J. Klein, Blokhuis Charlotte, Scherpbier Henriette J., Jansen Hans P. G., Kootstra Neeltje A., Dallinga-Thie Geesje M., van Deventer Sander J. H., Tsimikas Sotirios, Pajkrt Dasja, van den Hof M., Blokhuis C., Cohen S., Pajkrt D., Scherpbier H. J., Kuijpers T. W., van der Plas A., Weijsenfeld A., ter Stege J. S., Kootstra N. A., Caan M. W. A., Mutsaerts H. J. M. M., Majoie C. B. L. M., Verbraak F. D., Schmand B., Geurtsen G., Mathot R. A. A., Wit F. W. N. M., Reiss P., Teunissen C. E., Kuhle J., Meijer J. C. M. Elevated Lipoprotein(a) in Perinatally HIV-Infected Children Compared with Healthy Ethnicity-Matched Controls Open forum infectious diseases 2019;6 (9) [PubMed]
• Edridge Arthur W. D., Deijs Martin, Namazzi Ruth, Cristella Cosimo, Jebbink Maarten F., Maurer Irma, Kootstra Neeltje A., Buluma Linda R., van Woensel Job B. M., de Jong Menno D., Idro Richard, Boele van Hensbroek Michael, van der Hoek Lia Novel Orthobunyavirus Identified in the Cerebrospinal Fluid of a Ugandan Child With Severe Encephalopathy Clinical infectious diseases 2019;68 (1):139-142 [PubMed]
• Kroeze Stefanie, Wit Ferdinand W, Rossouw Theresa M, Steel Helen C, Kityo Cissy M, Siwale Margaret, Akanmu Sulaimon, Mandaliya Kishor, de Jager Marleen, Ondoa Pascale, Reiss Peter, Rinke de Wit Tobias F, Kootstra Neeltje, Hamers Raph L Plasma Biomarkers of Human Immunodeficiency Virus-Related Systemic Inflammation and Immune Activation in Sub-Saharan Africa Before and During Suppressive Antiretroviral Therapy Journal of infectious diseases 2019;220 (6):1029-1033 [PubMed]
• Hertoghs Nina, Nijmeijer Bernadien M., van Teijlingen Nienke H., Fenton-May Angharad E., Kaptein Tanja M., van Hamme John L., Kappes John C., Kootstra Neeltje A., Hahn Beatrice H., Borrow Persephone, Ribeiro Carla M. S., Geijtenbeek Teunis B. H. Sexually transmitted founder HIV-1 viruses are relatively resistant to Langerhans cell-mediated restriction PLoS ONE 2019;14 (12) [PubMed]
• Blokhuis C., Peeters C. F. W., Cohen S., Scherpbier H. J., Kuijpers T. W., Reiss P., Kootstra N. A., Teunissen C. E., Pajkrt D. Systemic and intrathecal immune activation in association with cerebral and cognitive outcomes in paediatric HIV Scientific reports 2019;9 (1) [PubMed]
• Kruize Zita, Kootstra Neeltje A. The Role of Macrophages in HIV-1 Persistence and Pathogenesis Frontiers in microbiology 2019;10 [PubMed]

2018

• van den Hof Malon, Blokhuis Charlotte, Cohen Sophie, Scherpbier Henriette J., Wit Ferdinand W. N. M., Pistorius M. C. M., Kootstra Neeltje A., Teunissen Charlotte E., Mathot Ron A. A., Pajkrt Dasja CNS penetration of ART in HIV-infected children Journal of antimicrobial chemotherapy 2018;73 (2):484-489 [PubMed]
• van der Ree Meike H., Jansen Louis, Welkers Matthijs R. A., Reesink Hendrik W., Feenstra K. Anton, Kootstra Neeltje A. Deep sequencing identifies hepatitis B virus core protein signatures in chronic hepatitis B patients Antiviral research 2018;158:213-225 [PubMed]
• Merat Sabrina J., van de Berg Dorien, Bru Camille, Yasuda Etsuko, Breij Esther, Kootstra Neeltje, Prins Maria, Molenkamp Richard, Bakker Arjen Q., de Jong Menno D., Spits Hergen, Schinkel Janke, Beaumont Tim Multiplex flow cytometry-based assay to study the breadth of antibody responses against E1E2 glycoproteins of hepatitis C virus Journal of immunological methods 2018;454:15-26 [PubMed]
• De Francesco Davide, Verboeket Sebastiaan O, Underwood Jonathan, Bagkeris Emmanouil , Wit Ferdinand W, Mallon Patrick W G, Winston Alan, Reiss Peter, Sabin Caroline A, Study group members AMC , Reiss P. , Wit F. W. N. M., Kooij K. W., van Zoest R. A. , Verheij E. , Verboeket Sebastiaan O., Prins M. , Kootstra N. A., Harskamp-Holwerda A. M. , Maurer Irma, Mangas Ruiz M. M., Boeser-Nunnink B. D. M. , Geerlings S. E. , Goorhuis A. , Hovius J. W. R. , Nellen F. J. B. , van der Poll Tom, Prins J. M. , Wiersinga W. J. , van Vugt M. , de Bree G. J. , Postema P. G. , Bisschop P. H. L. T., Serlie M. J. M. , Dekker E. , van der Velde N. , Willemsen J. M. R., Vogt L. , Portegies P. , Schmand B. A. , Geurtsen G. J. , Verbraak F. D. , Visser I. , Nieuwkerk P. T. , Majoie C. B. L. M. , Caan M. W. A. , van Lunsen H. W. , van den Born B. J. H. , Stroes E. S. G. Patterns of co-occurring comorbidities in people living with HIV Open forum infectious diseases 2018;5 (11):ofy272 [PubMed]
• van Zoest Rosan A., Underwood Jonathan, de Francesco Davide, Sabin Caroline A., Cole James H., Wit Ferdinand W., Caan Matthan W. A., Kootstra Neeltje A., Fuchs Dietmar, Zetterberg Henrik, Majoie Charles B. L. M., Portegies Peter, Winston Alan, Sharp David J., Gisslén Magnus, Reiss Peter, Winston A., Prins M., Schim van der Loeff M. F., Schouten J., Schmand B., Geurtsen G. J., Sharp D. J., Villaudy J., Berkhout B., Gisslén M., Pasternak A., Sabin C. A., Guaraldi G., Bürkle A., Libert C., Franceschi C., Kalsbeek A., Fliers E., Hoeijmakers J., Pothof J., van der Valk M., Bisschop P. H., Zaheri S., Burger D., Cole J. H., Zikkenheiner W., Janssen F. R., Underwood J., Kooij K. W., Doyle N., Verbraak F., Demirkaya N., Weijer K., Boeser-Nunnink B. Structural Brain Abnormalities in Successfully Treated HIV Infection: Associations With Disease and Cerebrospinal Fluid Biomarkers Journal of infectious diseases 2018;217 (1):69-81 [PubMed]
• Ploquin Mickaël J., Casrouge Armanda, Madec Yoann, Noël Nicolas, Jacquelin Beatrice, Huot Nicolas, Duffy Darragh, Jochems Simon P., Micci Luca, Lécuroux Camille, Boufassa Faroudy, Booiman Thijs, Garcia-Tellez Thalia, Ghislain Mathilde, Grand Roger Le, Lambotte Olivier, Kootstra Neeltje, Meyer Laurence, Goujard Cecile, Paiardini Mirko, Albert Matthew L., Müller-Trutwin Michaela Systemic DPP4 activity is reduced during primary HIV-1 infection and is associated with intestinal RORC+CD4+ cell levels: a surrogate marker candidate of HIV-induced intestinal damage Journal of the International AIDS Society 2018;21 (7) [PubMed]
• de Francesco Davide, Wit Ferdinand W., Cole James H., Kootstra Neeltje A., Winston Alan, Sabin Caroline A., Underwood Jonathan, van Zoest Rosan A., Schouten Judith, Kooij Katherine W., Prins Maria, Guaraldi Giovanni, Caan Matthan W. A., Burger David, Franceschi Claudio, Libert Claude, Bürkle Alexander, Reiss Peter The ‘COmorBidity in Relation to AIDS’ (COBRA) cohort: Design, methods and participant characteristics PLoS ONE 2018;13 (3) [PubMed]

2017

• Hoornenborg Elske, Prins Maria, Achterbergh Roel C. A., Woittiez Lycke R., Cornelissen Marion, Jurriaans Suzanne, Kootstra Neeltje A., Anderson Peter L., Reiss Peter, de Vries Henry J. C., Prins Jan M., de Bree Godelieve J. Acquisition of wild-type HIV-1 infection in a patient on pre-exposure prophylaxis with high intracellular concentrations of tenofovir diphosphate: a case report Lancet HIV 2017;4 (11):E522-E528 [PubMed]
• Medina-Ramírez Max, Garces Fernando, Escolano Amelia, Skog Patrick, de Taeye Steven W., del Moral-Sanchez Ivan, McGuire Andrew T., Yasmeen Anila, Behrens Anna-Janina, Ozorowski Gabriel, van den Kerkhof Tom L. G. M., Freund Natalia T., Dosenovic Pia, Hua Yuanzi, Gitlin Alexander D., Cupo Albert, van der Woude Patricia, Golabek Michael, Sliepen Kwinten, Blane Tanya, Kootstra Neeltje, van Breemen Mariëlle J., Pritchard Laura K., Stanfield Robyn L., Crispin Max, Ward Andrew B., Stamatatos Leonidas, Klasse Per Johan, Moore John P., Nemazee David, Nussenzweig Michel C., Wilson Ian A., Sanders Rogier W. Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo Journal of experimental medicine 2017;214 (9):2573-2590 [PubMed]
• Stelma Femke, Willemse Sophie B., Erken Robin, de Niet Annikki, Sinnige Marjan J., van Dort Karel, Zaaijer Hans L., van Leeuwen Ester M. M., Kootstra Neeltje A., Reesink Hendrik W. Dynamics of the Immune Response in Acute Hepatitis B Infection Open forum infectious diseases 2017;4 (4):UNSP ofx231 [PubMed]
• Booiman Thijs, Wit Ferdinand W., Maurer Irma, de Francesco Davide, Sabin Caroline A., Harskamp Agnes M., Prins Maria, Garagnani Paolo, Pirazzini Chiara, Franceschi Claudio, Fuchs Dietmar, Gisslén Magnus, Winston Alan, Reiss Peter, Kootstra Neeltje A., Schouten J., Kooij K. W., van Zoest R. A., Elsenga B. C., Janssen F. R., Heidenrijk M., Zikkenheiner W., van der Valk M., Booiman T., Harskamp-Holwerda A. M., Boeser-Nunnink B., Maurer I., Mangas Ruiz M. M., Girigorie A. F., Villaudy J., Frankin E., Pasternak A., Berkhout B., van der Kuyl T., Portegies P., Schmand B. A., Geurtsen G. J., ter Stege J. A., Klein Twennaar M., Majoie C. B. L. M., Caan M. W. A., Su T., Weijer K., Bisschop P. H. L. T., Kalsbeek A., Wezel M., Visser I., Ruhé H. G., Franceschi C., Garagnani P. High Cellular Monocyte Activation in People Living With Human Immunodeficiency Virus on Combination Antiretroviral Therapy and Lifestyle-Matched Controls Is Associated With Greater Inflammation in Cerebrospinal Fluid Open forum infectious diseases 2017;4 (3):ofx108 [PubMed]
• Gringhuis Sonja I., Hertoghs Nina, Kaptein Tanja M., Zijlstra-Willems Esther M., Sarrami-Fooroshani Ramin, Sprokholt Joris K., van Teijlingen Nienke H., Kootstra Neeltje A., Booiman Thijs, van Dort Karel A., Ribeiro Carla M. S., Drewniak Agata, Geijtenbeek Teunis B. H. HIV-1 blocks the signaling adaptor MAVS to evade antiviral host defense after sensing of abortive HIV-1 RNA by the host helicase DDX3 Nature immunology 2017;18 (2):225-235 [PubMed]
• Gringhuis Sonja I., Hertoghs Nina, Kaptein Tanja M., Zijlstra-Willems Esther M., Sarrami-Fooroshani Ramin, Sprokholt Joris K., van Teijlingen Nienke H., Kootstra Neeltje A., Booiman Thijs, van Dort Karel A., Ribeiro Carla M. S., Drewniak Agata, Geijtenbeek Teunis B. H. HIV-1 blocks the signaling adaptor MAVS to evade antiviral host defense after sensing of abortive HIV-1 RNA by the host helicase DDX3 (vol 18, pg 225, 2017) Nature immunology 2017;18 (4):474 [PubMed]
• Bartelsman M., Joore I. K., van Bergen J. E., Hogewoning A. A., Zuure F. R., van Veen M. G., Deug F., Heidenrijk M., Prins J. M., Prins M. [= Maria], Smit P. J., van der Valk M., Reiss P., de Bree G. J., Hoornenborg E., Davidovich U., Geerlings S. E., Oomen A., van sighem A., Zuilhof W., Achterbergh R. C. A., van Agtmael M., Ananworanich J., van de Beek D., van den Berk G. E. L., Berkhout B., Berretty B., Bezemer D., Blok W. L., Bomers M., Boucher C. A. B., Brokking W., Burger D., Brinkman K., de Bruin M., Geijtenbeek T. B. H., Godfried M. H., Goorhuis A., van der Helm J. J., Hovius J. W., Kootstra N. A., van der Meer J. T., Nellen F. J., Pasternak A. O., van der Poll T., van Rooijen M. S., de Vries H. J., van Vugt M., Wiersinga W. J., Wit F. W. HIV testing week 2015: lowering barriers for HIV testing among high-risk groups in Amsterdam BMC infectious diseases 2017;17 (1):529 [PubMed]
• Stelma Femke, de Niet Annikki, Sinnige Marjan J., van Dort Karel A., van Gisbergen Klaas P. J. M., Verheij Joanne, van Leeuwen Ester M. M., Kootstra Neeltje A., Reesink Hendrik W. Human intrahepatic CD69 + CD8+ T cells have a tissue resident memory T cell phenotype with reduced cytolytic capacity Scientific reports 2017;7 (1):6172 [PubMed]
• Stelma Femke, van der Ree Meike H., Sinnige Marjan J., Brown Anthony, Swadling Leo, de Vree J. Marleen L., Willemse Sophie B., van der Valk Marc, Grint Paul, Neben Steven, Klenerman Paul, Barnes Eleanor, Kootstra Neeltje A., Reesink Hendrik W. Immune phenotype and function of natural killer and T cells in chronic hepatitis C patients who received a single dose of anti-MicroRNA-122, RG-101 Hepatology (Baltimore, Md.) 2017;66 (1):57-68 [PubMed]
• van der Ree Meike H., Stelma Femke, Willemse Sophie B., Brown Anthony, Swadling Leo, van der Valk Marc, Sinnige Marjan J., van Nuenen Ad C., de Vree J. Marleen L., Klenerman Paul, Barnes Eleanor, Kootstra Neeltje A., Reesink Hendrik W. Immune responses in DAA treated chronic hepatitis C patients with and without prior RG-101 dosing Antiviral research 2017;146:139-145 [PubMed]
• Stelma Femke Immune responses in hepatitis B and C virus infection 2017. 286p. ISBN 9789461828347. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Beuers U. H. W., Geijtenbeek T. B. H.; Co-supervisors: Reesink H. W., Kootstra N. A.)
• Cole James H., Underwood Jonathan, Caan Matthan W. A., de Francesco Davide, van Zoest Rosan A., Leech Robert, Wit Ferdinand W. N. M., Portegies Peter, Geurtsen Gert J., Schmand Ben A., Schim van der Loeff Maarten F., Franceschi Claudio, Sabin Caroline A., Majoie Charles B. L. M., Winston Alan, Reiss Peter, Sharp David J., Schouten J., Kooij K. W., Elsenga B. C., Janssen F. R., Heidenrijk M., Schrijver J. H. N., Zikkenheiner W., van der Valk M., Henderiks A., Kootstra N. A., Harskamp-Holwerda A. M., Maurer I., Ruiz M. M. Mangas, Booiman T., Girigorie A. F., Villaudy J., Frankin E., Pasternak A., Berkhout B., van der Kuyl T., Stege J. A. ter, Twennaar M. Klein, Su T., Siteur-van Rijnstra E., Weijer K., Bisschop P. H. L. T., Kalsbeek A., Wezel M., Visser I., Ruhé H. G., Tembo L., Stott M., Prins M. [= Maria] Increased brain-predicted aging in treated HIV disease Neurology 2017;88 (14):1349-1357 [PubMed]
• Blokhuis Charlotte, Doeleman Susanne, Cohen Sophie, Demirkaya Nazli, Scherpbier Henriëtte J., Kootstra Neeltje A., Kuhle Jens, Teunissen Charlotte E., Verbraak Frank D., Pajkrt Dasja Inflammatory and Neuronal Biomarkers Associated With Retinal Thinning in Pediatric HIV Investigative ophthalmology & visual science 2017;58 (13):5985-5992 [PubMed]
• van der Ree Meike H. MicroRNA's in chronic hepatitis B and C virus infection 2017. 235p. ISBN 9789461827944. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Beuers U. H. W.; Co-supervisors: Reesink H. W. , Kootstra N. A.)
• de Groen R. A., Groothuismink Z. M. A., van Oord G., Kootstra N. A., Janssen H. L. A., Prins M. [= Maria], Schinkel J., Boonstra A. NK cells in self-limited HCV infection exhibit a more extensively differentiated, but not memory-like, repertoire Journal of viral hepatitis 2017;24 (11):917-926 [PubMed]
• van der Ree Meike H., Jansen Louis, Kruize Zita, van Nuenen Ad C., van Dort Karel A., Takkenberg R. Bart, Reesink Hendrik W., Kootstra Neeltje A. Plasma MicroRNA Levels Are Associated With Hepatitis B e Antigen Status and Treatment Response in Chronic Hepatitis B Patients Journal of infectious diseases 2017;215 (9):1421-1429 [PubMed]
• van der Ree Meike H., de Vree J. Marleen, Stelma Femke, Willemse Sophie, van der Valk Marc, Rietdijk Svend, Molenkamp Richard, Schinkel Janke, van Nuenen Ad C., Beuers Ulrich, Hadi Salah, Harbers Marten, van der Veer Eva, Liu Kai, Grundy John, Patick Amy K., Pavlicek Adam, Blem Jacqueline, Huang Michael, Grint Paul, Neben Steven, Gibson Neil W., Kootstra Neeltje A., Reesink Hendrik W. Safety, tolerability, and antiviral effect of RG-101 in patients with chronic hepatitis C: a phase 1B, double-blind, randomised controlled trial Lancet 2017;389 (10070):709-717 [PubMed]
• Booiman Thijs, Wit Ferdinand W., Girigorie Arginell F., Maurer Irma, de Francesco Davide, Sabin Caroline A., Harskamp Agnes M., Prins Maria, Franceschi Claudio, Deeks Steven G., Winston Alan, Reiss Peter, Kootstra Neeltje A. Terminal differentiation of T cells is strongly associated with CMV infection and increased in HIV-positive individuals on ART and lifestyle matched controls PLoS ONE 2017;12 (8):e0183357 [PubMed]
• Jansen Louis, Welkers Matthijs R. A., van Dort Karel A., Takkenberg R. Bart, Lopatin Uri, Zaaijer Hans L., de Jong Menno D., Reesink Hendrik W., Kootstra Neeltje A. Viral minority variants in the core promoter and precore region identified by deep sequencing are associated with response to peginterferon and adefovir in HBeAg negative chronic hepatitis B patients Antiviral research 2017;145:87-95 [PubMed]

2016

• Kooij Katherine W., Wit Ferdinand W. N. M., Booiman Thijs, van der Valk Marc, Schim van der Loeff Maarten F., Kootstra Neeltje A., Reiss Peter, Schouten J., van Zoest R. A., Verheij E., Elsenga B. C., Prins M., Martens M., Moll S., Berkel J., Totté M., Visser G. R., May L., Kovalev S., Newsum A., Boeser-Nunnink B., Geerlings S. E., Godfried M. H., Goorhuis A., Hovius J. W. R., van der Meer J. T. M., Nellen F. J. B., van der Poll T., Prins J. M., Wiersinga W. J., van Vugt M., Postema P. G., Bisschop P. H. L. T., Serlie M. J. M., Dekker E., van der Velde N., Vogt L., Portegies P., Schmand B. A., Geurtsen G. J., Verbraak F. D., Demirkaya N., Nieuwkerk P. T., Langebeek N., van Steenwijk R. P., Majoie C. B. L. M., Caan M. W. A., van Lunsen H. W., van den Born B. J. H., Stroes E. S. G. Cigarette Smoking and Inflammation, Monocyte Activation, and Coagulation in HIV-Infected Individuals Receiving Antiretroviral Therapy, Compared With Uninfected Individuals Journal of infectious diseases 2016;214 (12):1817-1821 [PubMed]
• Schouten Judith, Su Tanja, Wit Ferdinand W., Kootstra Neeltje A., Caan Matthan W. A., Geurtsen Gert J., Schmand Ben A., Stolte Ineke G., Prins Maria, Majoie Charles B., Portegies Peter, Reiss Peter, van der Valk M., Kooij K. W., van Zoest R. A., Elsenga B. C., Prins M., Stolte I. G., Martens M., Moll S., Berkel J., Möller L., Visser G. R., Gras L. A. J., van Leeuwen E., Geerlings S. E., Godfried M. H., Goorhuis A., van der Meer J. T. M., Nellen F. J. B., van der Poll T., Prins J. M., Wiersinga W. J., Postema P. G., Bisschop P. H. L. T., Serlie M. J. M., Dekker E., de Rooij S. E. J. A., Vogt L., van Eck-Smit B. L. F., de Jong M., Richel D. J., Verbraak F. D., Demirkaya N., Ruhé H. G., Nieuwkerk P. T., van Steenwijk R. P., van Lunsen H. W., van den Born B. J. H., Stroes E. S. G. Determinants of reduced cognitive performance in HIV-1-infected middle-aged men on combination antiretroviral therapy AIDS (London, England) 2016;30 (7):1027-1038 [PubMed]
• Kooij Katherine W., Schouten Judith, Wit Ferdinand W. N. M., van der Valk Marc, Kootstra Neeltje A., Stolte Ineke G., van der Meer Jan T. M., Prins Maria, Grobbee Diederick E., van den Born Bert-Jan H., Reiss Peter Difference in Aortic Stiffness Between Treated Middle-Aged HIV Type 1-Infected and Uninfected Individuals Largely Explained by Traditional Cardiovascular Risk Factors, With an Additional Contribution of Prior Advanced Immunodeficiency JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES 2016;73 (1):55-62 [PubMed]
• Ploquin Mickaël J., Madec Yoann, Casrouge Armanda, Huot Nicolas, Passaes Caroline, Lécuroux Camille, Essat Asma, Boufassa Faroudy, Jacquelin Béatrice, Jochems Simon P., Petitjean Gaël, Angin Mathieu, Gärtner Kathleen, Garcia-Tellez Thalía, Noël Nicolas, Booiman Thijs, Boeser-Nunnink Brigitte D., Roques Pierre, Saez-Cirion Asier, Vaslin Bruno, Dereudre-Bosquet Nathalie, Barré-Sinoussi Françoise, Ghislain Mathilde, Rouzioux Christine, Lambotte Olivier, Albert Matthew L., Goujard Cécile, Kootstra Neeltje, Meyer Laurence, Müller-Trutwin Michaela C. Elevated Basal Pre-infection CXCL10 in Plasma and in the Small Intestine after Infection Are Associated with More Rapid HIV/SIV Disease Onset PLoS pathogens 2016;12 (8):e1005774 [PubMed]
• Jansen L., Kootstra Neeltje A., van Dort Karel A., Takkenberg R. Bart, Reesink Hendrik W., Zaaijer Hans L. Hepatitis B Virus Pregenomic RNA Is Present in Virions in Plasma and Is Associated With a Response to Pegylated Interferon Alfa-2a and Nucleos(t)ide Analogues Journal of infectious diseases 2016;213 (2):224-232 [PubMed]
• van de Klundert Maarten A. A., van den Biggelaar Maartje, Kootstra Neeltje A., Zaaijer Hans L. Hepatitis B Virus Protein X Induces Degradation of Talin-1 Viruses 2016;8 (10):281 [PubMed]
• van Zoest Rosan A., Wit Ferdinand W., Kooij Katherine W., van der Valk Marc, Schouten Judith, Kootstra Neeltje A., Wiersinga W. Joost, Prins Maria, van den Born Bert-Jan H., Reiss Peter Higher Prevalence of Hypertension in HIV-1-Infected Patients on Combination Antiretroviral Therapy Is Associated With Changes in Body Composition and Prior Stavudine Exposure Clinical infectious diseases 2016;63 (2):205-213 [PubMed]
• Setiawan Laurentia C. HIV-1 adaptation to the host: The viral capsid and host factors 2016. 143p. ISBN 9789462993020. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Geijtenbeek T. B. H.; Co-supervisor: Kootstra N. A.)
• van den Kerkhof Tom L. G. M., de Taeye Steven W., Boeser-Nunnink Brigitte D., Burton Dennis R., Kootstra Neeltje A., Schuitemaker Hanneke, Sanders Rogier W., van Gils Marit J. HIV-1 escapes from N332-directed antibody neutralization in an elite neutralizer by envelope glycoprotein elongation and introduction of unusual disulfide bonds Retrovirology 2016;13 (1):48 [PubMed]
• Demirkaya Nazli, Wit Ferdinand W. N. M., van den Berg Thomas J. T. P., Kooij Katherine W., Prins Maria, Schlingemann Reinier O., Abramoff Michael D., Reiss Peter, Verbraak Frank D., van der Valk M., Schouten J. [=Judith], van Zoest R. A., Elsenga B. C., Martens M., Moll S., Berkel J., Totté M., Visser G. R., Kovalev S., Kootstra N. A., van Leeuwen E., Geerlings S. E., Godfried M. H., Goorhuis A., Hovius J. W. R., van der Meer J. T. M., Nellen F. J. B., van der Poll T., Prins J. M., Wiersinga W. J., Postema P. G., Bisschop P. H. L. T., Serlie M. J. M., Dekker E., de Rooij S. E. J. A., Vogt L., Portegies P., Schmand B. A., Geurtsen G. J., van Eck-Smit B. L. F., de Jong M., Richel D. J., Ruhé H. G., Nieuwkerk P. T., van Steenwijk R. P., Majoie C. B. L. M., Caan M. W. A., van Lunsen H. W., van den Born B. J. H., Stroes E. S. G. HIV-Associated Neuroretinal Disorder in Patients With Well-Suppressed HIV-Infection: A Comparative Cohort Study Investigative ophthalmology & visual science 2016;57 (3):1388-1397 [PubMed]
• Kooij Katherine W., Wit Ferdinand W. N. M., Schouten Judith, van der Valk Marc, Godfried Mieke H., Stolte Ineke G., Prins Maria, Falutz Julian, Reiss Peter, van Zoest R. A., Elsenga B. C., Prins M., Stolte I. G., Martens M., Moll S., Berkel J., Möller L., Visser G. R., Welling C., Zaheri S., Hillebregt M. M. J., Gras L. A. J., Ruijs Y. M. C., Benschop D. P., Kootstra N. A., Harskamp-Holwerda A. M., Maurer I., Ruiz M. M. Mangas, Girigorie A. F., van Leeuwen E., Janssen F. R., Heidenrijk M., Schrijver J. H. N., Zikkenheiner W., Wezel M., Jansen-Kok C. S. M., Geerlings S. E., Goorhuis A., Hovius J. W. R., van der Meer J. T. M., Nellen F. J. B., van der Poll T., Prins J. M., Wiersinga W. J., van Eden J., Henderiks A., van Hes A. M. H., Mutschelknauss M., Nobel H. E., Pijnappel F. J. J. HIV infection is independently associated with frailty in middle-aged HIV type 1-infected individuals compared with similar but uninfected controls AIDS (London, England) 2016;30 (2):241-250 [PubMed]
• Stelma F., Jansen L., Sinnige M. J., van Dort K. A., Takkenberg R. B., Janssen H. L. A., Reesink H. W., Kootstra N. A. HLA-C and KIR combined genotype as new response marker for HBeAg-positive chronic hepatitis B patients treated with interferon-based combination therapy Journal of viral hepatitis 2016;23 (8):652-659 [PubMed]
• van de Klundert M. A. A., Zaaijer H. L., Kootstra N. A. Identification of FDA-approved drugs that target hepatitis B virus transcription Journal of viral hepatitis 2016;23 (3):191-201 [PubMed]
• Willemse S. B., Jansen L., de Niet A., Sinnige M. J., Takkenberg R. B., Verheij J., Kootstra N. A., Reesink H. W. Intrahepatic IP-10 mRNA and plasma IP-10 levels as response marker for HBeAg-positive chronic hepatitis B patients treated with peginterferon and adefovir Antiviral research 2016;131:148-155 [PubMed]
• Kooij Katherine W., Wit Ferdinand W. N. M., van Zoest Rosan A., Schouten Judith, Kootstra Neeltje A., van Vugt Michèle, Prins Maria, Reiss Peter, van der Valk Marc Liver fibrosis in HIV-infected individuals on long-term antiretroviral therapy: associated with immune activation, immunodeficiency and prior use of didanosine AIDS (London, England) 2016;30 (11):1771-1780 [PubMed]
• Pasternak Alexander O., DeMaster Laura K., Kootstra Neeltje A., Reiss Peter, O'Doherty Una, Berkhout Ben Minor Contribution of Chimeric Host-HIV Readthrough Transcripts to the Level of HIV Cell-Associated gag RNA Journal of virology 2016;90 (2):1148-1151 [PubMed]
• van der Ree M. H., van der Meer A. J., van Nuenen A. C., de Bruijne J., Ottosen S., Janssen H. L., Kootstra N. A., Reesink H. W. Miravirsen dosing in chronic hepatitis C patients results in decreased microRNA-122 levels without affecting other microRNAs in plasma Alimentary pharmacology & therapeutics 2016;43 (1):102-113 [PubMed]
• Setiawan Laurentia C., van Dort Karel A., Rits Maarten A. N., Kootstra Neeltje A. Mutations in CypA Binding Region of HIV-1 Capsid Affect Capsid Stability and Viral Replication in Primary Macrophages AIDS research and human retroviruses 2016;32 (4):390-398 [PubMed]
• Blokhuis Charlotte, Kootstra Neeltje A., Caan Matthan W. A., Pajkrt Dasja Neurodevelopmental delay in pediatric HIV/AIDS: current perspectives Neurobehavioral HIV medicine 2016;7:1-13
• van Dalen Yvonne W., Blokhuis Charlotte, Cohen Sophie, ter Stege Jacqueline A., Teunissen Charlotte E., Kuhle Jens, Kootstra Neeltje A., Scherpbier Henriette J., Kuijpers Taco W., Reiss Peter, Majoie Charles B. L. M., Caan Matthan W. A., Pajkrt Dasja Neurometabolite Alterations Associated With Cognitive Performance in Perinatally HIV-Infected Children Medicine 2016;95 (12):e3093 [PubMed]
• Ribeiro Carla M. S., Sarrami-Forooshani Ramin, Setiawan Laurentia C., Zijlstra-Willems Esther M., van Hamme John L., Tigchelaar Wikky, van der Wel Nicole N., Kootstra Neeltje A., Gringhuis Sonja I., Geijtenbeek Teunis B. H. Receptor usage dictates HIV-1 restriction by human TRIM5α in dendritic cell subsets Nature 2016;540 (7633):448-452 [PubMed]
• de Niet Annikki, Stelma Femke, Jansen Louis, Sinnige Marjan J., Remmerswaal Ester B. M., Takkenberg R. Bart, Kootstra Neeltje A., Reesink Hendrik W., van Lier Rene A. W., van Leeuwen Ester M. M. Restoration of T cell function in chronic hepatitis B patients upon treatment with interferon based combination therapy Journal of hepatology 2016;64 (3):539-546 [PubMed]
• Cobos Jiménez Viviana, Wit Ferdinand W. N. M., Joerink Maaike, Maurer Irma, Harskamp Agnes M., Schouten Judith, Prins Maria, van Leeuwen Ester M. M., Booiman Thijs, Deeks Steven G., Reiss Peter, Kootstra Neeltje A., van der Valk M., Kooij K. W., van Zoest R. A., Elsenga B. C., Prins M., Martens M., Boeser-Nunnink B., Geerlings S. E., Godfried M. H., Goorhuis A., Hovius J. W. R., Nellen F. J. B., van der Meer J. T. M., van der Poll T., Prins J. M., Wiersinga W. J., Postema P. G., Bisschop P. H. L. T., Serlie M. J. M., Dekker E., de Rooij S. E. J. A., Vogt L., Portegies P., Schmand B. A., Geurtsen G. J., van Eck-Smit B. L. F., de Jong M., Richel D. J., Verbraak F. D., Demirkaya N., Ruhé H. G., Nieuwkerk P. T., van Steenwijk R. P., Majoie C. B. L. M., Caan M. W. A., van Lunsen H. W., van den Born B. J. H., Stroes E. S. G. T-Cell Activation Independently Associates With Immune Senescence in HIV-Infected Recipients of Long-term Antiretroviral Treatment Journal of infectious diseases 2016;214 (2):216-225 [PubMed]
• Cornelissen Marion, Euler Zelda, van den Kerkhof Tom L. G. M., van Gils Marit J., Boeser-Nunnink Brigitte D. M., Kootstra Neeltje A., Zorgdrager Fokla, Schuitemaker Hanneke, Prins Jan M., Sanders Rogier W., van der Kuyl Antoinette C. The Neutralizing Antibody Response in an Individual with Triple HIV-1 Infection Remains Directed at the First Infecting Subtype AIDS research and human retroviruses 2016;32 (10-11):1135-1142 [PubMed]
• Jansen Louis Virus-host interplay in chronic hepatitis B: Predicting response to immunomodulating antiviral therapy 2016. 187p. [UvA Dissertations Online] University of Amsterdam. (Supervisors: Beuers U. H. W., Zaaijer H. L.; Co-supervisors: Reesink H. W., Kootstra N. A.)
• van de Klundert M. A. A. X: On the molecular biology of the hepatitis B virus X protein 2016. 179p. ISBN 9789461698179. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Zaaijer H. L.; Co-supervisor: Kootstra N. A.)

2015

• Setiawan Laurentia C., Kootstra Neeltje A. Adaptation of HIV-1 to rhTrim5α-mediated restriction in vitro Virology 2015;486:239-247 [PubMed]
• Cuadrado Eloy, Booiman Thijs, van Hamme John L., Jansen Machiel H., van Dort Karel A., Vanderver Adeline, Rice Gillian I., Crow Yanick J., Kootstra Neeltje A., Kuijpers Taco W. ADAR1 Facilitates HIV-1 Replication in Primary CD4(+) T Cells PLoS ONE 2015;10 (12):e0143613 [PubMed]
• Spits Hilde B., Grijsen Marlous L., Steingrover Radjin, Nanlohy Nening M., Kootstra Neeltje, Borghans José A. M., van Baarle Debbie, Prins Jan M., Schellens Ingrid M. M. A lower viral set point but little immunological impact after early treatment during primary HIV infection Viral immunology 2015;28 (3):134-144 [PubMed]
• Jansen Louis, de Niet Annikki, Makowska Zuzanna, Dill Michael T., van Dort Karel A., Terpstra Valeska, Bart Takkenberg R., Janssen Harry L. A., Heim Markus H., Kootstra Neeltje A., Reesink Hendrik W. An intrahepatic transcriptional signature of enhanced immune activity predicts response to peginterferon in chronic hepatitis B Liver international 2015;35 (7):1824-1832 [PubMed]
• Booiman Thijs, Loukachov Vladimir V., van Dort Karel A., van 't Wout Angélique B., Kootstra Neeltje A. DYRK1A Controls HIV-1 Replication at a Transcriptional Level in an NFAT Dependent Manner PLoS ONE 2015;10 (12):e0144229 [PubMed]
• Cobos Jiménez Viviana, Martinez Fernando O., Booiman Thijs, van Dort Karel A., van de Klundert Maarten A. A., Gordon Siamon, Geijtenbeek Teunis B. H., Kootstra Neeltje A. G3BP1 restricts HIV-1 replication in macrophages and T-cells by sequestering viral RNA Virology 2015;486:94-104 [PubMed]
• Booiman Thijs Host factors in HIV-1 replication: The good, the bad and the ugly 2015. 214p. ISBN 9789053359747. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Geijtenbeek T. B. H.; Co-supervisor: Kootstra N. A.)
• Letko Michael, Booiman Thijs, Kootstra Neeltje, Simon Viviana, Ooms Marcel Identification of the HIV-1 Vif and Human APOBEC3G Protein Interface Cell reports 2015;13 (9):1789-1799 [PubMed]
• van Aalderen Michiel C., Remmerswaal Ester B. M., Verstegen Niels J. M., Hombrink Pleun, ten Brinke Anja, Pircher Hanspeter, Kootstra Neeltje A., ten Berge Ineke J. M., van Lier René A. W. Infection history determines the differentiation state of human CD8+ T cells Journal of virology 2015;89 (9):5110-5123 [PubMed]
• van de Klundert Maarten A. A., Swart Marjolein, Zaaijer Hans L., Kootstra Neeltje A. Inhibition of histone deacetylases stimulates HBV replication independent of protein X Future Virology 2015;10 (4):351-356
• Stelma Femke, de Niet Annikki, Tempelmans Plat-Sinnige Marjan J., Jansen Louis, Takkenberg R. Bart, Reesink Hendrik W., Kootstra Neeltje A., van Leeuwen Ester M. M. Natural Killer Cell Characteristics in Patients With Chronic Hepatitis B Virus (HBV) Infection Are Associated With HBV Surface Antigen Clearance After Combination Treatment With Pegylated Interferon Alfa-2a and Adefovir Journal of infectious diseases 2015;212 (7):1042-1051 [PubMed]
• Hertoghs Nina, van der Aar Angelic M. G., Setiawan Laurentia C., Kootstra Neeltje A., Gringhuis Sonja I., Geijtenbeek Teunis B. H. SAMHD1 degradation enhances active suppression of dendritic cell maturation by HIV-1 Journal of immunology (Baltimore, Md. 2015;194 (9):4431-4437 [PubMed]
• Ondoa Pascale, Gautam Raju, Rusine John, Lutter Rene, Jurriaans Suzanne, Kootstra Neeltje, Karita Etienne, van de Wijgert Janneke Twelve-Month Antiretroviral Therapy Suppresses Plasma and Genital Viral Loads but Fails to Alter Genital Levels of Cytokines, in a Cohort of HIV-Infected Rwandan Women PLoS ONE 2015;10 (5):e0127201 [PubMed]
• Setiawan Laurentia C., Gijsbers Esther F., van Nuenen Adrianus C., Kootstra Neeltje A. Viral evolution in HLA-B27-restricted CTL epitopes in human immunodeficiency virus type 1-infected individuals Journal of general virology 2015;96 (8):2372-2380 [PubMed]

2014

• Schouten Judith, Wit Ferdinand W., Stolte Ineke G., Kootstra Neeltje A., van der Valk Marc, Geerlings Suzanne E., Prins Maria, Reiss Peter, Kooij K. W., van Zoest R. A., Elsenga B. C., Stolte I. G., Martens M., Moll S., Berkel J., Möller L., Visser G. R., Welling C., Zaheri S., Gras L. A. J., van Leeuwen E., Godfried M. H., Goorhuis A., van der Meer J. T. M., Nellen F. J. B., van der Poll T., Prins J. M., Wiersinga W. J., Postema P. G., Bisschop P. H. L. T., Serlie M. J. M., Dekker E., de Rooij S. E. J. A., Vogt L., Portegies P., Schmand B. A., Geurtsen G. J., van Eck-Smit B. L. F., de Jong M., Richel D. J., Verbraak F. D., Demirkaya N., Ruhé H. G., Nieuwkerk P. T., van Steenwijk R. P., Majoie C. B. L. M., Caan M. W. A., van Lunsen H. W., van den Born B. J. H., Stroes E. S. G. Cross-sectional comparison of the prevalence of age-associated comorbidities and their risk factors between HIV-infected and uninfected individuals: the AGEhIV cohort study Clinical infectious diseases 2014;59 (12):1787-1797 [PubMed]
• Schellens Ingrid M. M., Spits Hilde B., Navis Marjon, Westerlaken Geertje H. A., Nanlohy Nening M., Coffeng Luc E., Kootstra Neeltje, Miedema Frank, Schuitemaker Hanneke, Borghans José A. M., van Baarle Debbie Differential characteristics of cytotoxic T lymphocytes restricted by the protective HLA alleles B*27 and B*57 in HIV-1 infection JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES 2014;67 (3):236-245 [PubMed]
• Bunders Madeleine J., van Hamme John L., Jansen Machiel H., Boer Kees, Kootstra Neeltje A., Kuijpers Taco W. Fetal exposure to HIV-1 alters chemokine receptor expression by CD4+T cells and increases susceptibility to HIV-1 Scientific reports 2014;4:6690 [PubMed]
• Booiman Thijs, Setiawan Laurentia C., Kootstra Neeltje A. Genetic variation in Trex1 affects HIV-1 disease progression AIDS (London, England) 2014;28 (17):2517-2521 [PubMed]
• Jansen Louis, de Niet Annikki, Stelma Femke, van Iperen Erik P. A., van Dort Karel A., Tempelmans Plat-Sinnige Marjan J., Takkenberg R. Bart, Chin Daniel J., Zwinderman A. H. Koos, Lopatin Uri, Kootstra Neeltje A., Reesink Hendrik W. HBsAg loss in patients treated with peginterferon alfa-2a and adefovir is associated with SLC16A9 gene variation and lower plasma carnitine levels Journal of hepatology 2014;61 (4):730-737 [PubMed]
• Cobos Jiménez Viviana HIV-1 infection in macrophages and genes involved throughout: big eaters versus small invaders 2014. 171p. ISBN 9789461824127. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Geijtenbeek T. B. H.; Co-supervisor: Kootstra N. A.)
• Dispinseri Stefania, Saba Elisa, Vicenzi Elisa, Kootstra Neeltje A., Schuitemaker Hanneke, Scarlatti Gabriella HIV-1 isolation from infected peripheral blood mononuclear cells Methods in molecular biology (Clifton, N.J.) 2014;1087:187-196 [PubMed]
• Gijsbers Esther F., van Nuenen Ad C., de la Peňa Alba Torrents, Bowles Emma J., Stewart-Jones Guillaume B., Schuitemaker Hanneke, Kootstra Neeltje A. Low level of HIV-1 evolution after transmission from mother to child Scientific reports 2014;4:5079 [PubMed]
• van der Ree Meike H., de Bruijne Joep, Kootstra Neeltje A., Jansen Peter Lm, Reesink Hendrik W. MicroRNAs: role and therapeutic targets in viral hepatitis Antiviral therapy 2014;19 (6):533-541 [PubMed]
• Cobos Jiménez Viviana, Willemsen Antonius M., Bradley Edward J., Baas Frank, van Kampen Antoine H. C., Kootstra Neeltje A. Next-generation sequencing of microRNAs in primary human polarized macrophages Genomics data 2014;2:181-183 [PubMed]
• Cobos Jiménez Viviana, Bradley Edward J., Willemsen Antonius M., van Kampen Antoine H. C., Baas Frank, Kootstra Neeltje A. Next-generation sequencing of microRNAs uncovers expression signatures in polarized macrophages Physiological genomics 2014;46 (3):91-103 [PubMed]
• Booiman Thijs, Cobos Jiménez Viviana, van Dort Karel A., van 't Wout Angélique B., Kootstra Neeltje A. Phosphodiesterase 8a supports HIV-1 replication in macrophages at the level of reverse transcription PLoS ONE 2014;9 (10):e109673 [PubMed]
• Booiman T., Kootstra N. A. Polymorphism in IFI16 affects CD4(+) T-cell counts in HIV-1 infection International journal of immunogenetics 2014;41 (6):518-520 [PubMed]

2013

• Isik Gözde, van Montfort Thijs, Boot Maikel, Cobos Jiménez Viviana, Kootstra Neeltje A., Sanders Rogier W. Chimeric HIV-1 envelope glycoproteins with potent intrinsic granulocyte-macrophage colony-stimulating factor (GM-CSF) activity PLoS ONE 2013;8 (4):e60126 [PubMed]
• Gijsbers Esther F., van Nuenen Ad C., Schuitemaker Hanneke, Kootstra Neeltje A. Gag sequence variation in a human immunodeficiency virus type 1 transmission cluster influences viral replication fitness Journal of general virology 2013;94 (2):354-359 [PubMed]
• Martinez Fernando O., Helming Laura, Milde Ronny, Varin Audrey, Melgert Barbro N., Draijer Christina, Thomas Benjamin, Fabbri Marco, Crawshaw Anjali, Ho Ling Pei, ten Hacken Nick H., Cobos Jiménez Viviana, Kootstra Neeltje A., Hamann Jörg, Greaves David R., Locati Massimo, Mantovani Alberto, Gordon Siamon Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences Blood 2013;121 (9):E57-E69 [PubMed]
• Gijsbers Esther F. HIV-1 evolution and adaptation to the host during the course of infection 2013. 160p. ISBN 9789461822918. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Schuitemaker H.; Co-supervisor: Kootstra N. A.)
• Gijsbers Esther F., Feenstra K. Anton, van Nuenen Ad C., Navis Marjon, Heringa Jaap, Schuitemaker Hanneke, Kootstra Neeltje A. HIV-1 replication fitness of HLA-B*57/58:01 CTL escape variants is restored by the accumulation of compensatory mutations in gag PLoS ONE 2013;8 (12):e81235 [PubMed]
• Jazaeri Farsani Seyed Mohammad, Jebbink Maarten F., Deijs Martin, Canuti Marta, van Dort Karel A., Bakker Margreet, Grady Bart P. X., Prins Maria, van Hemert Formijn J., Kootstra Neeltje A., van der Hoek Lia Identification of a new genotype of Torque Teno Mini virus Virology journal 2013;10 (1):323 [PubMed]
• Gijsbers Esther F., van Sighem Ard, Harskamp Agnes M., Welkers Matthijs R. A., de Wolf Frank, Brinkman Kees, Prins Jan M., Schuitemaker Hanneke, van 't Wout Angélique B., Kootstra Neeltje A. The presence of CXCR4-using HIV-1 prior to start of antiretroviral therapy is an independent predictor of delayed viral suppression PLoS ONE 2013;8 (10):e76255 [PubMed]

2012

• van de Klundert M. A. A., Cremer J., Kootstra N. A., Boot H. J., Zaaijer H. L. Comparison of the hepatitis B virus core, surface and polymerase gene substitution rates in chronically infected patients Journal of viral hepatitis 2012;19 (2):E34-E40 [PubMed]
• Cobos Jiménez Viviana, Booiman Thijs, de Taeye Steven W., van Dort Karel A., Rits Maarten A. N., Hamann Jörg, Kootstra Neeltje A. Differential expression of HIV-1 interfering factors in monocyte-derived macrophages stimulated with polarizing cytokines or interferons Scientific reports 2012;2:763 [PubMed]
• Stax Martijn J., Kootstra Neeltje A., van 't Wout Angélique B., Tanck Michael W. T., Bakker Margreet, Pollakis Georgios, Paxton William A. HIV-1 Disease Progression Is Associated with Bile-Salt Stimulated Lipase (BSSL) Gene Polymorphism PLoS ONE 2012;7 (3):e32534 [PubMed]
• Rachinger Andrea, Kootstra Neeltje A., Gijsbers Esther F., van den Kerkhof Tom L. G. M., Schuitemaker Hanneke, van 't Wout Angélique B. HIV-1 envelope diversity 1 year after seroconversion predicts subsequent disease progression AIDS (London, England) 2012;26 (12):1517-1522 [PubMed]
• Gijsbers Esther F., Schuitemaker Hanneke, Kootstra Neeltje A. HIV-1 transmission and viral adaptation to the host Future Virology 2012;7 (1):63-71
• Bunders Madeleine J., van der Loos Chris M., Klarenbeek Paul L., van Hamme John L., Boer Kees, Wilde Jim C. H., de Vries Niek, van Lier Rene A. W., Kootstra Neeltje, Pals Steven T., Kuijpers Taco W. Memory CD4(+)CCR5(+) T cells are abundantly present in the gut of newborn infants to facilitate mother-to-child transmission of HIV-1 Blood 2012;120 (22):4383-4390 [PubMed]
• Zoughlami Younes, Voermans Carlijn, Brussen Kim, van Dort Karel A., Kootstra Neeltje A., Maussang David, Smit Martine J., Hordijk Peter L., van Hennik Paula B. Regulation of CXCR4 conformation by the small GTPase Rac1: implications for HIV infection Blood 2012;119 (9):2024-2032 [PubMed]
• Bol Sebastiaan M., Booiman Thijs, van Manen Daniëlle, Bunnik Evelien M., van Sighem Ard I., Sieberer Margit, Boeser-Nunnink Brigitte, de Wolf Frank, Schuitemaker Hanneke, Portegies Peter, Kootstra Neeltje A., van 't Wout Angélique B. Single Nucleotide Polymorphism in Gene Encoding Transcription Factor Prep1 Is Associated with HIV-1-Associated Dementia PLoS ONE 2012;7 (2):e30990 [PubMed]
• van de Klundert Maarten A. A., van Hemert Formijn J., Zaaijer Hans L., Kootstra Neeltje A. The Hepatitis B Virus X Protein Inhibits Thymine DNA Glycosylase Initiated Base Excision Repair PLoS ONE 2012;7 (11):e48940 [PubMed]

2011

• Edo-Matas Diana, van Dort Karel A., Setiawan Laurentia C., Schuitemaker Hanneke, Kootstra Neeltje A. Comparison of in vivo and in vitro evolution of CCR5 to CXCR4 coreceptor use of primary human immunodeficiency virus type 1 variants Virology 2011;412 (2):269-277 [PubMed]
• van Manen Daniëlle, Delaneau Olivier, Kootstra Neeltje A., Boeser-Nunnink Brigitte D., Limou Sophie, Bol Sebastiaan M., Burger Judith A., Zwinderman Aeilko H., Moerland Perry D., van 't Slot Ruben, Zagury Jean-François, van 't Wout Angélique B., Schuitemaker Hanneke Genome-wide association scan in HIV-1-infected individuals identifying variants influencing disease course PLoS ONE 2011;6 (7):e22208 [PubMed]
• Bol Sebastiaan M., Cobos-Jimenez Viviana, Kootstra Neeltje A., van 't Wout Angelique B. HIV-1 and the macrophage Future Virology 2011;6 (2):187-208
• Schellens Ingrid M. M., Navis Marjon, van Deutekom Hanneke W. M., Boeser-Nunnink Brigitte, Berkhout Ben, Kootstra Neeltje, Miedema Frank, Keşmir Can, Schuitemaker Hanneke, van Baarle Debbie, Borghans José A. M. Loss of HIV-1-derived cytotoxic T lymphocyte epitopes restricted by protective HLA-B alleles during the HIV-1 epidemic AIDS (London, England) 2011;25 (14):1691-1700 [PubMed]
• Cobos-Jiménez Viviana, Booiman Thijs, Hamann Jörg, Kootstra Neeltje A. Macrophages and HIV-1 Current opinion in HIV and AIDS 2011;6 (5):385-390 [PubMed]
• Bol Sebastiaan M., Booiman Thijs, Bunnik Evelien M., Moerland Perry D., van Dort Karel, Strauss Jerome F., Sieberer Margit, Schuitemaker Hanneke, Kootstra Neeltje A., van 't Wout Angélique B. Polymorphism in HIV-1 dependency factor PDE8A affects mRNA level and HIV-1 replication in primary macrophages Virology 2011;420 (1):32-42 [PubMed]
• van Hemert Formijn J., van de Klundert Maarten A. A., Lukashov Vladimir V., Kootstra Neeltje A., Berkhout Ben, Zaaijer Hans L. Protein X of hepatitis B virus: origin and structure similarity with the central domain of DNA glycosylase PLoS ONE 2011;6 (8):e23392 [PubMed]

2010

• van Manen Danielle, Kootstra Neeltje A., Boeser-Nunnink Brigitte, Handulle Muna A. M., van 't Wout Angelique B., Schuitemaker Hanneke Association of HLA-C and HCP5 gene regions with the clinical course of HIV-1 infection (vol 23, pg 19, 2009) AIDS (London, England) 2010;24 (6):939
• Edo-Matas Diana, van Gils Marit J., Bowles Emma J., Navis Marjon, Rachinger Andrea, Boeser-Nunnink Brigitte, Stewart-Jones Guillaume B., Kootstra Neeltje A., Wout Angélique B. van 't, Schuitemaker Hanneke Genetic composition of replication competent clonal HIV-1 variants isolated from peripheral blood mononuclear cells (PBMC), HIV-1 proviral DNA from PBMC and HIV-1 RNA in serum in the course of HIV-1 infection Virology 2010;405 (2):492-504 [PubMed]

2009

• van Manen Daniëlle, Kootstra Neeltje A., Boeser-Nunnink Brigitte, Handulle Muna Am, Vanʼt Wout Angélique B., Schuitemaker Hanneke Association of HLA-C and HCP5 gene regions with the clinical course of HIV-1 infection AIDS (London, England) 2009;23 (1):19-28 [PubMed]
• Rits Maarten A. N. Cellular factors involved in HIV-1 replication 2009. 169p. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Schuitemaker H.; Co-supervisor: Kootstra N. A.)
• Navis Marjon Cellular immunity driving HIV-1 evolution 2009. 222p. ISBN 9789090238906. [UvA Dissertations Online] University of Amsterdam. (Supervisor: Schuitemaker H.; Co-supervisor: Kootstra N. A.)
• Bol Sebastiaan M., van Remmerden Yvonne, Sietzema Jantine G., Kootstra Neeltje A., Schuitemaker Hanneke, van 't Wout Angélique B. Donor variation in in vitro HIV-1 susceptibility of monocyte-derived macrophages Virology 2009;390 (2):205-211 [PubMed]
• van den Biggelaar Maartje, Bouwens Eveline A. M., Kootstra Neeltje A., Hebbel Robert P., Voorberg Jan, Mertens Koen Storage and regulated secretion of factor VIII in blood outgrowth endothelial cells Haematologica 2009;94 (5):670-678 [PubMed]

2008

• Navis Marjon, Schellens Ingrid M. M., van Swieten Peter, Borghans José A. M., Miedema Frank, Kootstra Neeltje A., van Baarle Debbie, Schuitemaker Hanneke A nonprogressive clinical course in HIV-infected individuals expressing human leukocyte antigen B57/5801 is associated with preserved CD8+ T lymphocyte responsiveness to the HW9 epitope in Nef Journal of infectious diseases 2008;197 (6):871-879 [PubMed]
• van den Biggelaar Maartje Factor VIII trafficking to Weibel-Palade bodies 2008. [UvA Dissertations Online] Universiteit van Utrecht: Sanquin research. (Supervisors: Mertens K., Storm G.; Co-supervisors: Voorberg J., Kootstra N. A.)
• van 't Wout Angélique B., Schuitemaker Hanneke, Kootstra Neeltje A. Isolation and propagation of HIV-1 on peripheral blood mononuclear cells Nature protocols 2008;3 (3):363-370 [PubMed]
• Navis Marjon, Edo Matas Diana, Rachinger Andrea, Koning Fransje A., van Swieten Peter, Kootstra Neeltje A., Schuitemaker Hanneke Molecular Evolution of Human Immunodeficiency Virus Type 1 upon Transmission between Human Leukocyte Antigen Disparate Donor-Recipient Pairs PLoS ONE 2008;3 (6):e2422 [PubMed]
• Rits Maarten A. N., van Dort Karel A., Kootstra Neeltje A. Polymorphisms in the Regulatory Region of the Cyclophilin A Gene Influence the Susceptibility for HIV-1 Infection PLoS ONE 2008;3 (12):e3975 [PubMed]
• van Manen Daniëlle, Rits Maarten A. N., Beugeling Corrine, van Dort Karel, Schuitemaker Hanneke, Kootstra Neeltje A. The effect of Trim5 polymorphisms on the clinical course of HIV-1 infection PLoS pathogens 2008;4 (2):e18 [PubMed]

2007

• Rits Maarten A. N., van Dort Karel A., Münk Carsten, Meijer Alexander B., Kootstra Neeltje A. Efficient transduction of simian cells by HIV-1-based lentiviral vectors that contain mutations in the capsid protein Molecular therapy 2007;15 (5):930-937 [PubMed]
• Kootstra Neeltje A., Navis Marjon, Beugeling Corrine, van Dort Karel A., Schuitemaker Hanneke The presence of the Trim5alpha escape mutation H87Q in the capsid of late stage HIV-1 variants is preceded by a prolonged asymptomatic infection phase AIDS (London, England) 2007;21 (15):2015-2023 [PubMed]
• Navis Marjon, Schellens Ingrid, van Baarle Debbie, Borghans José, van Swieten Peter, Miedema Frank, Kootstra Neeltje, Schuitemaker Hanneke Viral replication capacity as a correlate of HLA B57/B5801-associated nonprogressive HIV-1 infection Journal of immunology (Baltimore, Md. 2007;179 (5):3133-3143 [PubMed]

2006

• van Thienen Johannes V., Fledderus Joost O., Dekker Rob J., Rohlena Jakub, van IJzendoorn Gerben A., Kootstra Neeltje A., Pannekoek Hans, Horrevoets Anton J. G. Shear stress sustains atheroprotective endothelial KLF2 expression more potently than statins through mRNA stabilization Cardiovascular research 2006;72 (2):231-240 [PubMed]

2005

• Kootstra N. A., Schuitemaker H. Determination of cell tropism of HIV-1in: T. Zhu, editors. Human retrovirus protocols: virology and molecular biology. Totowa, NJ: Humana Press Inc.; 2005. p. 317-325
• Schuitemaker Hanneke, Kootstra Neeltje A. Determination of co-receptor usage of HIV-1 Methods in molecular biology (Clifton, N.J.) 2005;304:327-332 [PubMed]
• Schuitemaker H., Kootstra N. A. Determination of co-receptor usage of HIV-1in: T. Zhu, editors. Human retrovirus protocols: virology and molecular biology. Totowa, NJ: Humana Press Inc.; 2005. p. 327-332
• Schuitemaker Hanneke, Kootstra Neeltje A. Isolation, propagation, and titration of human immunodeficiency virus type 1 from peripheral blood of infected individuals Methods in molecular biology (Clifton, N.J.) 2005;304:17-24 [PubMed]
• Schuitemaker H., Kootstra N. A. Isolations, propagation, and titration of human immunodeficiency virus type 1 from peripheral blood of infected individualsin: T. Zhu, editors. Human retrovirus protocols: virology and molecular biology. Totowa, NJ: Humana Press Inc.; 2005. p. 17-24

2003

• Kootstra Neeltje A., Munk Carsten, Tonnu Nina, Landau Nathaniel R., Verma Inder M. Abrogation of postentry restriction of HIV-1-based lentiviral vector transduction in simian cells Proceedings of the National Academy of Sciences of the United States of America 2003;100 (3):1298-1303 [PubMed]
• Kootstra Neeltje A., Matsumura Ryusuke, Verma Inder M. Efficient production of human FVIII in hemophilic mice using lentiviral vectors Molecular therapy 2003;7 (5 Part 1):623-631 [PubMed]
• Kootstra Neeltje A., Verma Inder M. Gene therapy with viral vectors Annual review of pharmacology and toxicology 2003;43:413-439 [PubMed]

2002

• MacKenzie Tippi C., Kobinger Gary P., Kootstra Neeltje A., Radu Antoneta, Sena-Esteves Miguel, Bouchard Sarah, Wilson James M., Verma Inder M., Flake Alan W. Efficient transduction of liver and muscle after in utero injection of lentiviral vectors with different pseudotypes Molecular therapy 2002;6 (3):349-358 [PubMed]

2001

• Pfeifer A., Brandon E. P., Kootstra N., Gage F. H., Verma I. M. Delivery of the Cre recombinase by a self-deleting lentiviral vector: efficient gene targeting in vivo Proceedings of the National Academy of Sciences of the United States of America 2001;98 (20):11450-11455 [PubMed]
• Pfeifer A., Kessler T., Yang M., Baranov E., Kootstra N., Cheresh D. A., Hoffman R. M., Verma I. M. Transduction of liver cells by lentiviral vectors: analysis in living animals by fluorescence imaging Molecular therapy 2001;3 (3):319-322 [PubMed]

2000

• Kootstra N. A., Zwart B. M., Schuitemaker H. Diminished human immunodeficiency virus type 1 reverse transcription and nuclear transport in primary macrophages arrested in early G(1) phase of the cell cycle Journal of virology 2000;74 (4):1712-1717 [PubMed]

1999

• Kootstra N. A., Schuitemaker H. Phenotype of HIV-1 lacking a functional nuclear localization signal in matrix protein of gag and Vpr is comparable to wild-type HIV-1 in primary macrophages Virology 1999;253 (2):170-180 [PubMed]
• Berkowitz R. D., van't Wout A. B., Kootstra N. A., Moreno M. E., Linquist-Stepps V. D., Bare C., Stoddart C. A., Schuitemaker H., McCune J. M. R5 strains of human immunodeficiency virus type 1 from rapid progressors lacking X4 strains do not possess X4-type pathogenicity in human thymus Journal of virology 1999;73 (9):7817-7822 [PubMed]

1998

• van't Wout A. B., Ran L. J., Kuiken C. L., Kootstra N. A., Pals S. T., Schuitemaker H. Analysis of the temporal relationship between human immunodeficiency virus type 1 quasispecies in sequential blood samples and various organs obtained at autopsy Journal of virology 1998;72 (1):488-496 [PubMed]
• Blaak H., van't Wout A. B., Brouwer M., Cornelissen M., Kootstra N. A., Albrecht-van Lent N., Keet R. P., Goudsmit J., Coutinho R. A., Schuitemaker H. Infectious cellular load in human immunodeficiency virus type 1 (HIV-1)-infected individuals and susceptibility of peripheral blood mononuclear cells from their exposed partners to non-syncytium-inducing HIV-1 as major determinants for HIV-1 transmission in homosexual couples Journal of virology 1998;72 (1):218-224 [PubMed]
• Kootstra N. A., Schuitemaker H. Proliferation-dependent replication in primary macrophages of macrophage-tropic HIV type 1 variants AIDS research and human retroviruses 1998;14 (4):339-345 [PubMed]

1997

• Kootstra N. A., Miedema F., Schuitemaker H. Analysis of CD8+ T lymphocyte-mediated nonlytic suppression of autologous and heterologous primary human immunodeficiency virus type 1 isolates AIDS research and human retroviruses 1997;13 (8):685-693 [PubMed]

1996

• van 't Wout A. B., de Jong M. D., Kootstra N. A., Veenstra J., Lange J. M., Boucher C. A., Schuitemaker H. Changes in cellular virus load and zidovudine resistance of syncytium-inducing and non-syncytium-inducing human immunodeficiency virus populations under zidovudine pressure: a clonal analysis Journal of infectious diseases 1996;174 (4):845-849 [PubMed]
• Koot M., van 't Wout A. B., Kootstra N. A., de Goede R. E., Tersmette M., Schuitemaker H. Relation between changes in cellular load, evolution of viral phenotype, and the clonal composition of virus populations in the course of human immunodeficiency virus type 1 infection Journal of infectious diseases 1996;173 (2):349-354 [PubMed]

1994

• Fouchier R. A., Brouwer M., Kootstra N. A., Huisman H. G., Schuitemaker H. HIV-1 macrophage tropism is determined at multiple levels of the viral replication cycle Journal of clinical investigation 1994;94 (5):1806-1814 [PubMed]
• Kootstra N. A., van 't Wout A., Huisman H. G., Miedema F., Schuitemaker H. Interference of interleukin-10 with human immunodeficiency virus type 1 replication in primary monocyte-derived macrophages Journal of virology 1994;68 (11):6967-6975 [PubMed]
• van't Wout A. B., Kootstra N. A., Mulder-Kampinga G. A., Albrecht-van Lent N., Scherpbier H. J., Veenstra J., Boer K., Coutinho R. A., Miedema F., Schuitemaker H. Macrophage-tropic variants initiate human immunodeficiency virus type 1 infection after sexual, parenteral, and vertical transmission Journal of clinical investigation 1994;94 (5):2060-2067 [PubMed]
• Schuitemaker H., Kootstra N. A., Fouchier R. A., Hooibrink B., Miedema F. Productive HIV-1 infection of macrophages restricted to the cell fraction with proliferative capacity EMBO journal 1994;13 (24):5929-5936 [PubMed]
• Roos M. T., de Leeuw N. A., Claessen F. A., Huisman H. G., Kootstra N. A., Meyaard L., Schellekens P. T., Schuitemaker H., Miedema F. Viro-immunological studies in acute HIV-1 infection AIDS (London, England) 1994;8 (11):1533-1538 [PubMed]

1993

• Schuitemaker H., Groenink M., Meyaard L., Kootstra N. A., Fouchier R. A., Gruters R. A., Huisman H. G., Tersmette M., Miedema F. Early replication steps but not cell type-specific signalling of the viral long terminal repeat determine HIV-1 monocytotropism AIDS research and human retroviruses 1993;9 (7):669-675 [PubMed]
• Schuitemaker H., Meyaard L., Kootstra N. A., Dubbes R., Otto S. A., Tersmette M., Heeney J. L., Miedema F. Lack of T cell dysfunction and programmed cell death in human immunodeficiency virus type 1-infected chimpanzees correlates with absence of monocytotropic variants Journal of infectious diseases 1993;168 (5):1140-1147 [PubMed]

1992

• Schuitemaker H., Koot M., Kootstra N. A., Dercksen M. W., de Goede R. E., van Steenwijk R. P., Lange J. M., Schattenkerk J. K., Miedema F., Tersmette M. Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population Journal of virology 1992;66 (3):1354-1360 [PubMed]
• Schuitemaker H., Kootstra N. A., Groenink M., de Goede R. E., Miedema F., Tersmette M. Differential tropism of clinical HIV-1 isolates for primary monocytes and promonocytic cell lines AIDS research and human retroviruses 1992;8 (9):1679-1682 [PubMed]
• Fouchier R. A., Groenink M., Kootstra N. A., Tersmette M., Huisman H. G., Miedema F., Schuitemaker H. Phenotype-associated sequence variation in the third variable domain of the human immunodeficiency virus type 1 gp120 molecule Journal of virology 1992;66 (5):3183-3187 [PubMed]
• Schuitemaker H., Kootstra N. A., Koppelman M. H., Bruisten S. M., Huisman H. G., Tersmette M., Miedema F. Proliferation-dependent HIV-1 infection of monocytes occurs during differentiation into macrophages Journal of clinical investigation 1992;89 (4):1154-1160 [PubMed]

1991

• Schuitemaker H., Kootstra N. A., de Goede R. E., de Wolf F., Miedema F., Tersmette M. Monocytotropic human immunodeficiency virus type 1 (HIV-1) variants detectable in all stages of HIV-1 infection lack T-cell line tropism and syncytium-inducing ability in primary T-cell culture Journal of virology 1991;65 (1):356-363 [PubMed]

1990

• Schuitemaker H., Kootstra N. A., van Oers M. H., van Lambalgen R., Tersmette M., Miedema F. Induction of monocyte proliferation and HIV expression by IL-3 does not interfere with anti-viral activity of zidovudine Blood 1990;76 (8):1490-1493 [PubMed]