- Tummers W. S., Groen J. V., Sibinga Mulder B. G., Farina-Sarasqueta A., Morreau J., Putter H., van de Velde C. J., Vahrmeijer A. L., Bonsing B. A., Mieog J. S., Swijnenburg R. J. Impact of resection margin status on recurrence and survival in pancreatic cancer surgery British journal of surgery 2019;106 (8):1055-1065 [PubMed]
- Tummers Willemieke S., Kimura Richard H., Abou-Elkacem Lotfi, Beinat C., Vahrmeijer Alexander L., Swijnenburg Rutger-Jan, Willmann Juergen K., Gambhir Sanjiv S. Development and preclinical validation of a cysteine knottin peptide targeting integrin avb6 for near-infrared fluorescent-guided surgery in pancreatic cancer Clinical cancer research 2018;24 (7):1667-1676 [PubMed]
- Charehbili A., Koek M. B. G., de Mol van Otterloo J. C. A., Bronkhorst M. W. G. A., van der Zwaal P., Thomassen B., Waasdorp E. J., Govaert J. A., Bosman A., van den Bremer J., Ploeg A. J., Putter H., Meijs A. P., van de Velde C. J. H., van Gijn W., Swijnenburg R. J. Cluster-randomized crossover trial of chlorhexidine-alcohol versus iodine-alcohol for prevention of surgical-site infection (SKINFECT trial) BJS Open 2019;3 (5):617-622 [PubMed]
- Tummers Willemieke S, Farina-Sarasqueta Arantza, Boonstra Martin C, Prevoo Hendrica A, Sier Cornelis F, Mieog Jan S, Morreau Johannes, van Eijck Casper H, Kuppen Peter J, Bonsing Bert A, Vahrmeijer Alexander L, Swijnenburg Rutger-Jan Selection of optimal molecular targets for tumor-specific imaging in pancreatic ductal adenocarcinoma Oncotarget 2017;8 (34):56816-56828 [PubMed]
- Swijnenburg Rutger-Jan, Schrepfer Sonja, Govaert Johannes A, Cao Feng, Ransohoff Katie, Sheikh Ahmad Y, Haddad Munif, Connolly Andrew J, Davis Mark M, Robbins Robert C, Wu Joseph C Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenografts Proceedings of the National Academy of Sciences of the United States of America 2008;105 (35):12991-12996 [PubMed]
Education
2015 – 2018 Fellowship HPB Surgical Oncology, Leiden University Medical Center (LUMC)
Focus: Hepatobiliary, pancreas and endocrine surgery
2015 – 2017 Training Abdominal Organ Donor Procurement Surgery, LUMC
2016 (Feb) Clinical Observership HPB Surgical Oncology, Stanford University, Stanford (CA, USA)
2008 – 2015 Surgery Resident, LUMC and Haaglanden Medical Center; Specialization: GI Surgery - Surgical Oncology
2009 (Apr) Ph.D. thesis defense; Characterization of embryonic stem cell transplantation immunobiology using molecular imaging, Leiden University
Promotors: Prof. dr. J.F. Hamming, Prof. dr. R.C. Robbins (Cardiothoracic Surgery, Stanford)
2004 – 2006 Internships, LUMC; M.D. since June 2006
1997 – 2003 Medical School, Leiden University
1990 – 1996 Pre-university level high school, Meridiaan College, Amersfoort
Positions and employment
2018 – present Staff member, Hepatobiliary and Pancreatic Surgery, Amsterdam UMC, locations AMC and VUmc
2018 Board Certified in abdominal organ donor procurement surgery, LUMC
2017 – present Member, Committee Continues Professional Education, NVVH
2016 – 2018 Course Coordinator Image-Guided Interventions, Masters Clinical Technology, Leiden-Delft-Erasmus Alliance
2016 – present Member, Scientific Committee, Dutch Hepatobiliary Audit
2016 – present Board Certified Surgical Oncologist and Gastro-intestinal Surgeon
2014 – 2015 Board member, Foundation for Scientific Research in Surgical Specialties (SWOAHS)
2010 – present Co-founder, Medical and Scientific Advisor of the Lisa Waller Hayes Pancreatic Cancer Foundation / Living With Hope
1999 – 2003 Organ allocation coordinator, Eurotransplant International Foundation, Leiden (NL)
Research Experience
2019 – present PhD Supervisor (co-promotor) of Burak Gorgec, MD
Clinical value of MRI in colorectal liver metastases
2018 – present PhD Supervisor (co-promotor) of Karen Bolhuis, MD
Treatment strategies of in colorectal cancer patients with initially unresectable liver-only metastases (CAIRO-V study)
2018 – present PhD Supervisor (co-promotor) of Maurice Zwart, MSc
Implementation of robotic hepatobiliary and pancreatic surgery
2017 – present PhD Supervisor (co-promotor) of Friso Achterberg, MD.
Molecular imaging of liver and pancreatic tumors
2015 – present PhD Supervisor (co-promotor) of Willemieke Tummers, MD, PhD.
Thesis: Diagnostic and Intraoperative Targeted Molecular Imaging for Pancreatic Cancer (Defense 13th Nov 2018)
2011 – 2012 Postdoc, Department of Surgical Oncology, Leiden University Medical Center
Multimodality molecular image-guided surgical oncology
2012 – 2017 Principle investigator SKINFECT trial: Chlorhexidine-alcohol versus Iodine-alcohol for preoperative antisepsis, Multicenter study in region South-West
2006 – 2008 PhD Research Fellow, Stanford University School of Medicine, Department of Cardiothoracic Surgery and Molecular Imaging Program at Stanford, Stanford (CA, USA)
Molecular imaging of human embryonic stem cell transplantation immunobiology
2003 – 2004 Visiting Researcher, Stanford University School of Medicine, Department of Cardiothoracic Surgery, Stanford (CA, USA) Embryonic stem cell transplantation for myocardial repair
Grants and Honors
2019 Cancer Center Amsterdam Grant, €150.000,- (Principle Investigator)
2017 – 2021 Dutch Cancer Society (KWF) Young Investigator Grant, €650.000,- (Principle Investigator)
2016 Stanford Cancer Institute Research grant, $150.000,- (Co-investigator)
2015 Surgical Intuitive Research Grant, $50.000,- (Principle investigator)
2013 ESSO Fellowship Grant to attend the Films Workshop for Clinical Cancer Research
2013 European Research Council Advanced Grant Prof. C.J.H. van de Velde, €2.5 mln (Writing committee)
2006 European Society for Organ Transplantation-Astellas Study and Research Grant, €25.000
2006 Fulbright Scholarship, $12.500
2005 Hippocrates Foundation Research Prize, €2.500
2003 VSB Foundation study grant, €5.000
2003 and 2006 Professor Michaël-van Vloten research grant, €10.000
2003 Leiden University Foundation study grant, €2.500
Extracurricular activities
2000 – 2002 Treasurer of the 125th anniversary congress of the Medical Society Hippocrates, Kos (EL)
1999 – 2000 Vice-President of the Minerva Student Union
Publications (H-index 20)
Cluster‐randomized crossover trial of chlorhexidine–alcohol versus iodine–alcohol for prevention of surgical‐site infection (SKINFECT trial). Charehbili A, Koek MB, de Mol van Otterloo JC, Bronkhorst MW, van der Zwaal P, Thomassen B, Waasdorp EJ, Govaert JA, Bosman A, van den Bremer J, Ploeg AJ, Putter H, Meijs AP, van de Velde CJ, van Gijn W, Swijnenburg RJ. BJS Open 2019. Published online 20 May 2019
van der Poel MJ, Fichtinger RS, Bemelmans M, Bosscha K, Braat AE, de Boer MT, Dejong CHC, Doornebosch PG, Draaisma WA, Gerhards MF, Gobardhan PD, Gorgec B, Hagendoorn J, Kazemier G, Klaase J, Leclercq WKG, Liem MS, Lips DJ, Marsman HA, Mieog JSD, Molenaar QI, Nieuwenhuijs VB, Nota CL, Patijn GA, Rijken AM, Slooter GD, Stommel MWJ, Swijnenburg RJ, Tanis PJ, Te Riele WW, Terkivatan T, van den Tol PM, van den Boezem PB, van der Hoeven JA, Vermaas M, Hilal MA, van Dam RM, Besselink MG; Dutch Liver Collaborative Group. Implementation and outcome of minor and major minimally invasive liver surgery in the Netherlands. HPB (Oxford). 2019 Jun 21.
Suker M, Koerkamp BG, Coene PP, van der Harst E, Bonsing BA, Vahrmeijer AL, Mieog JSD, Swijnenburg RJ, Dwarkasing RS, Roos D, van Eijck CHJ. Yield of staging laparoscopy before treatment of locally advanced pancreatic cancer to detect occult metastases. Eur J Surg Oncol. 2019 Jun 3.
Caballero C, Burock S, Carrion-Alvarez L, Nilsson H, Ruers T, Senellart P, Rivoire M, Stattner S, Primavesi F, Troisi R, Gruenberger T, Heil J, Schnitzbauer AA, Rahbari NN, Swijnenburg RJ, Malik H, Protic M, Kataoka K, Mauer M, Ducreux M, Poston G, Evrard S. Building a collaboration to improve surgical research through. EORTC/ESSO 1409-CLIMB study: A prospective liver metastasis database with an integrated quality assurance program. Eur J Surg Oncol. 2019 May 30
Sibinga Mulder BG, Feshtali S, Fariña Sarasqueta A, Vahrmeijer AL, Swijnenburg RJ, Bonsing BA, Mieog JSD. A Prospective Clinical Trial to Determine the Effect of Intraoperative Ultrasound on Surgical Strategy and Resection Outcome in Patients with Pancreatic Cancer. Ultrasound Med Biol. 2019 Aug;45(8):2019-2026.
Buisman FE, Homs MYV, Grünhagen DJ, Filipe WF, Bennink RJ, Besselink MGH, Borel Rinkes IHM, Bruijnen RCG, Cercek A, D'Angelica MI, van Delden OM, Donswijk ML, van Doorn L, Doornebosch PG, Emmering J, Erdmann JI, IJzerman NS, Grootscholten C, Hagendoorn J, Kemeny NE, Kingham TP, Klompenhouwer EG, Kok NFM, Koolen S, Kuhlmann KFD, Kuiper MC, Lam MGE, Mathijssen RHJ, Moelker A, Oomen-de Hoop E, Punt CJA, Te Riele WW, Roodhart JML, Swijnenburg RJ, Prevoo W, Tanis PJ, Vermaas M, Versleijen MWJ, Veuger FP, Weterman MJ, Verhoef C, Groot Koerkamp B. Adjuvant hepatic arterial infusion pump chemotherapy and resection versus resection alone in patients with low-risk resectable colorectal liver metastases - the multicenter randomized controlled PUMP trial. BMC Cancer. 2019 Apr 5;19(1):327.
van der Werf LR, Kok NFM, Buis CI, Grünhagen DJ, Hoogwater FJH, Swijnenburg RJ, Dulk MD, Dejong KCHC, Klaase JM; Dutch Hepato Biliary Audit Group. Implementation and first results of a mandatory, nationwide audit on liver surgery. HPB (Oxford). 2019 Mar 26. pii: S1365-182X(19)30107-8.
Tummers WS, Groen JV, Sibinga Mulder BG, Farina-Sarasqueta A, Morreau J, Putter H, van de Velde CJ, Vahrmeijer AL, Bonsing BA, Mieog JS, Swijnenburg RJ. Impact of resection margin status on recurrence and survival in pancreatic cancer surgery. Br J Surg 2019 Jul;106(8):1055-1065.
Hanna-Sawires RG, Groen JV, Klok FA, Tollenaar RAEM, Mesker WE, Swijnenburg RJ, Vahrmeijer AL, Bonsing BA, Mieog JSD. Outcomes following pancreatic surgery using three different thromboprophylaxis regimens. Br J Surg. 2019 May;106(6):765-773.
Tummers WS, Miller SE, Teraphongphom NT, van den Berg NS, Hasan A, Longacre TA, Fisher GA, Bonsing BA, Vahrmeijer AL, Gambhir SS, Swijnenburg RJ, Rosenthal EL, Poultsides GA. Detection of visually occult metastatic lymph nodes using molecularly targeted fluorescent imaging during surgical resection of pancreatic cancer. HPB (Oxford). 2019 Jul;21(7):883-890.
Tummers WS, Warram JM, van den Berg NS, Miller SE, Swijnenburg RJ, Vahrmeijer AL, Rosenthal EL. Recommendations for reporting on emerging optical imaging agents to promote clinical approval. Theranostics. 2018 Oct 22;8(19):5336-5347.
Sibinga Mulder BG, Visser K, Feshtali S, Vahrmeijer AL, Swijnenburg RJ, Hartgrink HH, van den Boom R, Burgmans MC, Mieog JSD. Gadoxetic acid-enhanced magnetic resonance imaging significantly influences the clinical course in patients with colorectal liver metastases. BMC Med Imaging. 2018 Nov 15;18(1):44.
Handgraaf HJM, Sibinga Mulder BG, Shahbazi Feshtali S, Boogerd LSF, van der Valk MJM, Fariña Sarasqueta A, Swijnenburg RJ, Bonsing BA, Vahrmeijer AL, Mieog JSD. Staging laparoscopy with ultrasound and near-infrared fluorescence imaging to detect occult metastases of pancreatic and periampullary cancer. PLoS One. 2018 Nov 1;13(11)
Hoogstins CES, Boogerd LSF, Sibinga Mulder BG, Mieog JSD, Swijnenburg RJ, van de Velde CJH, Farina Sarasqueta A, Bonsing BA, Framery B, Pèlegrin A, Gutowski M, Cailler F, Burggraaf J, Vahrmeijer AL. Image-Guided Surgery in Patients with Pancreatic Cancer: First Results of a Clinical Trial Using SGM-101, a Novel Carcinoembryonic Antigen-Targeting, Near-Infrared Fluorescent Agent. Ann Surg Oncol. 2018 Oct;25(11):3350-3357.
Tummers WS, Willmann JK, Bonsing BA, Vahrmeijer AL, Gambhir SS, Swijnenburg RJ. Advances in Diagnostic and Intraoperative Molecular Imaging of Pancreatic Cancer. Pancreas. 2018 Jul;47(6):675-689.
Achterberg FB, Burgmans MC, Kapitein E, Ceha H, Hartgrink HH, Swijnenburg RJ. Ontwikkelingen in lokale behandeling van colorectale levermetastasen. Ned Tijdschr Oncol 2018.
Tummers WS, Miller SE, Teraphongphom NT, Gomez A, Steinberg I, Huland DM, Hong S, Kothapalli SR, Hasan A, Ertsey R, Bonsing BA, Vahrmeijer AL, Swijnenburg RJ, Longacre TA, Fisher GA, Gambhir SS, Poultsides GA, Rosenthal EL. Intraoperative Pancreatic Cancer Detection using Tumor-Specific Multimodality Molecular Imaging. Ann Surg Oncol. 2018 Jul;25(7):1880-1888.
Tummers WS, Kimura RH, Abou-Elkacem L, Vahrmeijer AL, Swijnenburg RJ, Willmann JK, Gambhir SS. Development and preclinical validation of a cysteine knottin peptide targeting Integrin αvβ6 for near-infrared fluorescent-guided surgery in pancreatic cancer. Clin Cancer Res. 2018 Apr 1;24(7):1667-1676.
Handgraaf HJM, Boogerd LSF, Shahbazi Feshtali S, Fariña Sarasqueta A, Snel M, Swijnenburg RJ, Vahrmeijer AL, Bonsing BA, Mieog JSD. Intraoperative Near-Infrared Fluorescence Imaging of Multiple Pancreatic Neuroendocrine Tumors: A Case Report. Pancreas. 2018 Jan;47(1):130-133.
Kooreman NG, de Almeida PE, Stack JP, Nelakanti RV, Diecke S, Shao NY, Swijnenburg RJ, Sanchez-Freire V, Matsa E, Liu C, Connolly AJ, Hamming JF, Quax PHA, Brehm MA, Greiner DL, Shultz LD, Wu JC. Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics. Cell Rep. 2017 Aug 22;20(8):1978-1990.
Sibinga Mulder BG, Mieog JSD, Farina Sarasqueta A, Handgraaf HJ, Vasen HFA, Swijnenburg RJ, Luelmo SAC, Feshtali S, Inderson A, Vahrmeijer AL, Bonsing BA, Wezel TV, Morreau H. Diagnostic value of targeted next-generation sequencing in patients with suspected pancreatic or periampullary cancer. J Clin Pathol. 2017. Aug 3.
Handgraaf HJM, Boogerd LSF, Höppener DJ, Peloso A, Sibinga Mulder BG, Hoogstins CES, Hartgrink HH, van de Velde CJH, Mieog JSD, Swijnenburg RJ, Putter H, Maestri M, Braat AE, Frangioni JV, Vahrmeijer AL. Long-term follow-up after near-infrared fluorescence-guided resection of colorectal liver metastases: A retrospective multicenter analysis. Eur J Surg Oncol. 2017 Aug;43(8):1463-1471.
Tummers WS, Farina-Sarasqueta A, Boonstra MC, Prevoo HA, Sier CF, Mieog JS, Morreau J, van Eijck CH, Kuppen PJ, van de Velde CJ, Bonsing BA, Vahrmeijer AL, Swijnenburg RJ. Selection of optimal molecular targets for tumor-specific imaging in pancreatic ductal adenocarcinoma. Oncotarget. 2017 May 26;8(34):56816-56828.
de Rooij T, van Hilst J, Vogel JA, van Santvoort HC, de Boer MT, Boerma D, van den Boezem PB, Bonsing BA, Bosscha K, Coene PP, Daams F, van Dam RM, Dijkgraaf MG, van Eijck CH, Festen S, Gerhards MF, Groot Koerkamp B, Hagendoorn J, van der Harst E, de Hingh IH, Dejong CH, Kazemier G, Klaase J, de Kleine RH, van Laarhoven CJ, Lips DJ, Luyer MD, Molenaar IQ, Nieuwenhuijs VB, Patijn GA, Roos D, Scheepers JJ, van der Schelling GP, Steenvoorde P, Swijnenburg RJ, Wijsman JH, Abu Hilal M, Busch OR, Besselink MG; Dutch Pancreatic Cancer Group. Minimally invasive versus open distal pancreatectomy (LEOPARD): study protocol for a randomized controlled trial. Trials. 2017 Apr 8;18(1):166.
Sibinga Mulder BG, Mieog JS, Handgraaf HJ, Farina Sarasqueta A, Vasen HF, Potjer TP, Swijnenburg RJ, Luelmo SA, Feshtali S, Inderson A, Vahrmeijer AL, Bonsing BA, van Wezel T, Morreau H. Targeted next-generation sequencing of FNA-derived DNA in pancreatic cancer. J Clin Pathol. 2016 Sep 26.
Ibrahim IS, Bonsing BA, Swijnenburg RJ, Welling L, Veenendaal RA, Wasser MN, Morreau H, Inderson A, Vasen HF. Dilemmas in the management of screen-detected lesions in patients at high risk for pancreatic cancer. Fam Cancer. 2016 Jul 12.
Boogerd LS, Handgraaf HJ, Lam HD, Braat AE, Baranski AG, Swijnenburg RJ, Frangioni JV, Vahrmeijer AL, Ringers J. Application of near-infrared fluorescence imaging during modified associating liver partition and portal vein ligation for staged hepatectomy. Surgery. 2016 May;159(5):1481-2.
de Geus SW, Boogerd LS, Swijnenburg RJ, Mieog JS, Tummers WS, Prevoo HA, Sier CF, Morreau H, Bonsing BA, van de Velde CJ, Vahrmeijer AL, Kuppen PJ. Selecting Tumor-Specific Molecular Targets in Pancreatic Adenocarcinoma: Paving the Way for Image-Guided Pancreatic Surgery. Mol Imaging Biol. 2016 Apr 29.
Charehbili A , Swijnenburg RJ, van de Velde CJ, van den Bremer J, van Gijn W. A retrospective analysis of surgical-site infections in a center that instantly switched from iodine-alcohol to chlorhexidine-alcohol for preoperative antisepsis. Surg Inf 2014 Jun;15(3):310-3
Verbeek FP, Schaafsma BE, Tummers QR, van der Vorst JR, van der Made WJ, Baeten CI, Bonsing BE, Frangioni JV, van der Velde CJ, Vahrmeijer AL, Swijnenburg RJ. Optimization of near-infrared fluorescence cholangiography for open and laparoscopic surgery. Surg Endos 2014 Apr;28(4):1076-82
van der Vorst JR, Schaafsma BE, Verbeek FP, Swijnenburg RJ, Tummers QR, Hutteman M, Hamming JF, Kievit J, Frangioni JV, van de Velde CJ, Vahrmeijer AL. Intraoperative near-infrared fluorescence imaging of parathryoid adenomas with use of low-dose methylene blue. Head Neck 2014 Jun;36(6):853-8.
Verbeek FP, van der Vorst JR, Schaafsma BE, Swijnenburg RJ, Gaarenstroom KN, Elzevier HW, van de Velde CJ, Frangioni JV, Vahrmeijer AL. Intraoperative near infrared fluorescence-guided identification of the ureters using low-dose methylene blue. J Urol. 2013 Aug;190(2):574-9.
van der Vorst JR, Schaafsma BE, Verbeek FP, Swijnenburg RJ, Hutteman M, Liefers GJ, van de Velde CJ, Frangioni JV, Vahrmeijer AL. Dose optimization for near-infrared fluorescence sentinel lymph node mapping in melanoma patients. Br J Dermatol. 2013 Jan;168(1):93-8
Verbeek FP, van der Vorst JR, Schaafsma BE, Hutteman M, Bonsing BA, van Leeuwen FW, Frangioni JV, van de Velde CJ, Swijnenburg RJ, Vahrmeijer AL. Image-guided hepatopancreatobiliary surgery using near-infrared fluorescent light. J Hepatobiliary Pancreat Sci. 2012
Swijnenburg RJ, Crane LM, Buddingh KT, van de Velde CJ, Vahrmeijer AL, van Dam GM. Intraoperatieve beeldvorming met fluorescentie. Ned Tijdschr Geneeskd. 2012; 156(11):A4316.
Swijnenburg RJ, Keizer J, Heslinga JM. Acute mesenteric venous thrombosis. Br J Surg 2010;97:1837
Swijnenburg RJ, Govaert JA, van der Bogt KE, Pearl JI, Huang M, Stein W, Hoyt G, Vogel H, Contag CH, Robbins RC, Wu JC. Timing of bone marrow cells has minimal effects on cell viability and cardiac recovery after myocardial infarction. Circulation Cardiovasc Imaging. 2010 Jan;3(1):77-85.
Govaert JA, Swijnenburg RJ, Schrepfer S, Xie X, van der Bogt KE, Hoyt G, Stein W, Ransohoff KJ, Robbins RC, Wu JC. Poor functional recovery after transplantation of diabetic bone marrow stem cells in ischemic myocardium. J Heart Lung Transplant. 2009 Nov;28(11):1158-1165.e1.
Van der Bogt KE, Sheik AY, Schrepfer S, Hoyt G, Cao F, Ransohoff K, Swijnenburg RJ, Pearl JI, Lee A, Fischbein M, Contag CH, Robbins RC, Wu JC. Comparison of different adult stem cell types for treatment of myocardial ischemia. Circulation 2008;118[14 suppl]:S121-9
Swijnenburg RJ, Schrepfer S, Govaert JA, Cao F, Ransohoff K, Sheikh AY, Haddad M, Connolly AJ, Davis MM, Robbins RC, Wu JC. Immunosuppressive therapy mitigates immunological rejection of human embryonic stem cell xenographs. PNAS 2008 Sep 2;105(35):12991-6
Swijnenburg RJ, Schrepfer S, Cao F, Pearl JI, Xie X, Connolly AJ, Robbins RC, Wu JC. In vivo imaging of embryonic stem cells reveals patterns of survival and immunological rejection following transplantation. Stem Cells and Development 2008. Dec;17(6):1023-9.
Swijnenburg RJ, Van der Bogt KE, Sheikh AY, Cao F, Wu JC. Clinical hurdles for transplantation of cardiomyocytes derived from human embryonic stem cells: Role of molecular imaging. Curr Opin Biotechnol. 2007 Feb;18(1):38-45
Van der Bogt KE, Swijnenburg RJ, Cao F, Wu JC. Molecular Imaging of Human Embryonic Stem Cells: Keeping an Eye on Differentiation, Tumorigenicity and Immunogenicity. Cell Cycle 2006 Dec;5(23):2748-52.
Kofidis T, Lebl DR, Swijnenburg RJ, Greve JM, Klima U, Gold J, Xu C, Robbins RC. Allopurinol/uricase and ibuprofen enhance engraftment of cardiomyocyte-enriched human embryonic stem cells and improve cardiac function following myocardial injury. Eur J Cardiothorac Surg. 2006 Jan;29(1):50-5.
Swijnenburg RJ, Tanaka M, Vogel H, Baker J, Kofidis T, Gunwan F, Lebl DR, Caffarelli AD, de Bruin JL, Fedoseyeva EV and Robbins RC. Embryonic Stem Cell Immunogenicity Increases upon Differentiation Following Transplantation into Ischemic Myocardium. Circulation 2005;112[suppl I]:I-166-I-172.
Tanaka M, Swijnenburg RJ, Gunawan F, Cao YA, de Bruin JL, Kofidis T, Fedoseyeva EV, Contag CH and Robbins RC. In Vivo Visualization of Cardiac Allograft Rejection and Trafficking Passenger Leucocytes Using Bioluminescence Imaging. Circulation 2005;112[suppl I]:I-105-I-110.
Coa YA, Bachmann MH, Beilhack A, Yang Y, Tanaka M, Swijnenburg RJ, Reeves R, Taylor-Edwards C, Schulz S, Doyle TC, Fathman CG, Robbins RC, Herzenberg LA, Negrin RS, Contag CH. Molecular Imaging Using Labeled Donor Tissues Reveals Patterns of Engraftment, Rejection, and Survival in Transplantation. Transplantation 2005;80(1):134-139.
Kofidis T, de Bruin JL, Yamane T, Tanaka M, Lebl DR, Swijnenburg RJ, Weissman IL and Robbins RC. Stimulation of Paracrine Pathways with Growth Factors Enhances Embryonic Stem cell Engraftment and Host Specific Differentiation in the Heart Following Ischemic Myocardial Injury. Circulation 2005;111(19):2486-93.
Kofidis T, de Bruin JL, Yamane T, Balsam LB, Lebl DR, Swijnenburg RJ, Tanaka M, Weissman IL, Robbins RC. Insulin-like growth factor promotes engraftment, differentiation, and functional improvement after transfer of embryonic stem cells for myocardial restoration. Stem Cells. 2004;22(7):1239-45.
Swijnenburg RJ, Lange CP, Salm LP. Non-invasieve visualisatie van coronairarteriele stenosen; ontwikkeling van Coronary Magnetic Resonance Angiography. Ned Tijdschr Geneesk Studenten Ed 2004 maart; 7(1)
Selection of presentations
Swijnenburg RJ. Strategies for Radiology and Surgery to Work Together to Optimize Fluorescence-guided Surgery (Invited).
International society for strategic studies on radiology (IS3R) symposium – August 2019
Swijnenburg RJ. Molecular Imaging to guide Hepatobiliary and Pancreatic Surgery (Invited)
MIPS seminar Stanford University – Feb 2019
Tummers WS, Swijnenburg RJ, Kimura RH, Abou-Elkacem L, Vahrmeijer AL, Willmann JK, Gambhir SS. Development and preclinical validation of a cysteine knottin peptide targeting Integrin αvβ6 for near-infrared fluorescent-guided surgery in pancreatic cancer.
EAHPBA 2017, Mainz (GE) and Dutch Surgical Society Annual Meeting 2017, Veldhoven (NL)
Charehbili A , Koek M, van de Velde CJ, van Gijn W, Swijnenburg RJ. Chlorhexidine-alcohol versus iodine-alcohol for preoperative antisepsis: the SKINFECT trial.
29th European Congress on Surgical Infections, Amsterdam (NL)
Charehbili A , Swijnenburg RJ, van de Velde CJ, van den Bremer J, van Gijn W. A retrospective analysis of surgical-site infections in a center that instantly switched from iodine-alcohol to chlorhexidine-alcohol for preoperative antisepsis.
29th European Congress on Surgical Infections, Amsterdam (NL)
Tummers WS, Farina-Sarasqueta A, Boonstra MC, Prevoo HA, Sier CF, Mieog JS, Morreau H, vd Velde CJ, van Eijck CH, Bonsing BA, Vahrmeijer AL, Swijnenburg RJ. Patterns of biomarker expression on pancreatic ductal adenocarcinoma following neoadjuvant radiochemotherapy: Implications for tumor-specific molecular imaging.
Dutch Surgical Society Annual Meeting 2016, Veldhoven (NL)
Tummers WS, Farina-Sarasqueta A, Boonstra MC, Cohen D, Prevoo HA, Sier CF, Mazar AP, Mieog JS, Morreau H, vd Velde CJ, Bonsing BA, Vahrmeijer AL, Swijnenburg RJ. Identification of biomarkers for tumor-specific molecular imaging in pancreatic ductal adenocarcinoma.
IHPBA World Congress, Sao Paolo(Brazil) 2016
de Geus SW, Swijnenburg RJ, Prevoo HA, Sier CF, Bonsing BA, Morreau H, van de Velde CJ, Vahrmeijer AL, Kuppen PJ. Selecting tumor-specific biomarkers in pancreatic and periampullary cancer: paving the way for image-guided surgery
European Society for Surgical Oncology Meeting, Liverpool (GB) 2014
Swijnenburg RJ, Pearl J, Cao F, Vogel H, Hamming JF, Robbins RC, Wu JC. Characterization of human embryonic stem cell immunogenicity in allogeneic humanized mice.
European Society for Surgical Research Annual Congress, Geneva (Switzerland) 2010
Swijnenburg RJ, Govaert JA, Stein W, van der Bogt KE, Pearl JI, Hoyt G, Vogel H, Robbins RC, Wu JC. Effect of Timing of Bone Marrow Cell Delivery on Cell Viability and Cardiac Recovery Following Myocardial Infarction. Circulation 2008;118(18 Supll 2):S790
American Heart Association’s Scientific Sessions, New Orleans (LA, USA) 2008
Swijnenburg RJ, Schrepfer S, Govaert JA, Cao F, Sheikh AY, Fischbein MP, Robbins RC, Wu JC. Immunosuppressive Therapy Mitigates Murine T-Cell Mediated Rejection of Human Embryonic Stem Cells following Transplantation.
The International Society for Heart and Lung Transplantation Scientific Sessions, Boston (MA, USA) 2008
Swijnenburg RJ, Tanaka M, Vogel H, Baker J, Gunawan F, Lebl DR, Caffarelli AD, Kofidis T and Robbins RC. Embryonic Stem Cell Immunogenicity Increases upon Differentiation in Ischemic Myocardium. Circulation 2004 Oct 26;110(17 Suppl 3):III-507
American Heart Association’s Scientific Sessions, New Orleans (LA, USA) 2004
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