R.H.A. Verhoeven PhD

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PhD R.H.A. Verhoeven

Position
Research Associate
Main activities
Research
Specialisation
Epidemiology of gastro-intestinal cancers
Focus of research

Although randomized-controlled trials should be regarded as the highest grade of evidence, clinical trials are also very costly, time-consuming and answer only one very specific question with often a limited external validity due to their strict inclusion criteria.

Real-world data (RWD) provide a much more realistic representation of the actual patient population and utilization and outcome of treatments in daily clinical practice. I therefore strongly believe that RCTs and RWD should be seen as complementary to each other.

My vision and focus of research is to optimize the utilization of RWD, with a special focus on application in esophageal and gastric cancer. By using innovative (and more standard) methodologies to analyze RWD I intend to contribute to the academic knowledge of these innovative methodologies. But at the same time try to create potential societal impact by presenting the output in such way that it can be used by physicians and patients to improve decision making and outcome in the daily clinical oncology practice.

Key publications
  • van Putten M., de Vos-Geelen J., Nieuwenhuijzen G. A. P., Siersema P. D., Lemmens V. E. P. P., Rosman C., van der Sangen M. J. C., Verhoeven R. H. A. Long-term survival improvement in oesophageal cancer in the Netherlands European journal of cancer (Oxford, England 2018;94:138-147 [PubMed]
  • Mokadem I., Dijksterhuis W. P. M., van Putten M., Heuthorst L., de Vos-Geelen J. M., Haj Mohammad N., Nieuwenhuijzen G. A. P., van Laarhoven H. W. M., Verhoeven R. H. A. Recurrence after preoperative chemotherapy and surgery for gastric adenocarcinoma: a multicenter study Gastric cancer 2019;22 (6):1263-1273 [PubMed]
  • Nelen S. D., van Putten M., Lemmens V. E. P. P., Bosscha K., de Wilt J. H. W., Verhoeven R. H. A. Effect of age on rates of palliative surgery and chemotherapy use in patients with locally advanced or metastatic gastric cancer British journal of surgery 2017;104 (13):1837-1846 [PubMed]
  • van Putten Margreet, Lemmens Valery E. P. P., van Laarhoven Hanneke W. M., Pruijt Hans F. M., Nieuwenhuijzen Grard A. P., Verhoeven Rob H. A. Poor compliance with perioperative chemotherapy for resectable gastric cancer and its impact on survival European journal of surgical oncology 2019;45 (10):1926-1933 [PubMed]
  • Brouwer Nelleke P. M., Bos Amanda C. R. K., Lemmens Valery E. P. P., Tanis Pieter J., Hugen Niek, Nagtegaal Iris D., de Wilt Johannes H. W., Verhoeven Rob H. A. An overview of 25 years of incidence, treatment and outcome of colorectal cancer patients International journal of cancer. Journal international du cancer 2018;143 (11):2758-2766 [PubMed]
All Publications
Research programmes

Prof. PhD H.W.M. van Laarhoven (Translational research in medical oncology)